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LDL

The carbonic anhydrases (or carbonate dehydratases) form a family of enzymes that catalyze the interconversion between carbon dioxide and water and the dissociated ions of carbonic acid (i.e. bicarbonate and hydrogen ions). The active site of most carbonic anhydrases contains a zinc ion. They are therefore classified as metalloenzymes. The enzyme maintains acid-base balance and helps transport carbon dioxide.

  • Imanixil
    T1556175689-93-9In house
    Imanixil (HOE-402 free base) 是 LDL 受体 (LDLR) 的诱导剂,是一种降血脂降胆固醇化合物,具有抗动脉粥样硬化活性,可抑制极低密度脂蛋白 (VLDL) 的产生。Imanixil通过刺激 LDL 受体途径发挥作用。
    • ¥ 1820
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  • Atorvastatin Sodium
    T20887134523-01-6In house
    Atorvastatin Sodium (Lipitor) 是一种HMG-CoA 还原酶的竞争性抑制剂,增加肝细胞上低密度脂蛋白(LDL)受体的表达。Atorvastatin sodium 处理抑制水汽蛋白4来减轻缺血性脑水肿。
    • ¥ 167 TargetMol
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  • Carvedilol phosphate hemihydrate
    T0342610309-89-2
    Carvedilol phosphate hemihydrate (BM 14190 phosphate hemihydrate) 是一种外消旋混合物,是一种非选择性β α-1受体阻断剂,具有抗高血压活性且缺乏内在拟交感神经活性。
    • ¥ 148
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  • Procyanidin A1
    TN1136103883-03-0
    Procyanidin A1 (Proanthocyanidin A1) 是一种原花青素二聚体,具有抗过敏作用,可抑制蛋白激酶 C 激活下游脱粒或 RBL-213 细胞内部储存的 Ca2+流入。
    • ¥ 828
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    TargetMol | Inhibitor Sale
  • Kudinoside D
    TN1836173792-61-5
    Kudinoside D 是 Ilex kudingcha 中三萜皂苷的主要天然成分之一。它能够调节 3T3-L1 脂肪细胞中 AMPK 途径,并可抑制脂肪形成。
    • ¥ 2150
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    TargetMol | Inhibitor Sale
  • Levosemotiadil
    T25701116476-16-5In house
    Levosemotiadil(SA 3212) 是一种新型钙拮抗剂,是一种非常有效的低密度脂蛋白氧化抑制剂。Levosemotiadil 可用于预防致死性心律失常。
    • ¥ 4960
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  • Probucol disuccinate
    T4179216168-45-5
    Probucol disucinate 是一种 Probucol 的衍生物。其中 Probucol 是脂质调节的化合物,它能降低 LDL-cholesterol 水平。
    • ¥ 162
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    TargetMol | Inhibitor Sale
  • Siamenoside I
    TN2208126105-12-2
    Siamenoside I 是一种罗汉果甜甙,具有多种生物学功能。
    • ¥ 443
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    TargetMol | Inhibitor Sale
  • Cleomiscosin C
    TN367584575-10-0
    Cleomiscosin C has antioxidant activity, it protects against the oxidative modification of apoB-100 induced by either Cu2+ or HOCl ( IC50s of 23.6 and 3.9 microM, respectively), suggests that it could be beneficial in preventing LDL oxidation in atheroscl
    • ¥ 2435
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  • Stachybotramide
    TN5057149598-71-0
    Stachybotramide preferentially stimulate the plasma cholesteryl ester transfer protein (CETP)-mediated transfer of cholesteryl esters (CE) from high density lipoprotein (HDL) to both very low density lipoprotein (VLDL) and low density lipoprotein (LDL).
    • ¥ 4420
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  • Isosalvianolic acid C
    TN1801142115-17-1
    Isosalvianolic acid C exhibits more potent activity than probucol except for salvianolic acid F .
    • ¥ 10360
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  • Erycibelline
    TN3989107633-95-4
    Erycibelline has antiobesity activity, it may be a useful therapeutic agent for body weight control by downregulating adipogenesis and lipogenesis.
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  • Ligupurpuroside B
    TN1869147396-02-9
    Ligupurpuroside B has antioxidant activity.
    • ¥ 3800
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  • Trichosanatine
    TN5174169626-16-8
    Trichosanatine and squamosamide, as potential candidates as lead compounds for further study in drug development process with the PP2A- α protein. Trichosanatine can alleviate oxidized low-density lipoprotein induced endothelial cells injury via inhibiting the LOX-1/p38 MAPK pathway.
    • ¥ 5700
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  • Alpinumisoflavone
    TN339734086-50-5
    Alpinumisoflavone has atheroprotective effects, may result from their ability to upregulate mechanisms promoting HDL-cholesterol and bile acid formation, it is endowed with estrogenic properties accounting, at least in part, for E. lysistemon effects. Alp
      询价
    • Ligupurpuroside A
      TN1868147396-01-8
      Ligupurpuroside A has antioxidant,and hypolipidemic effects, it can significantly inhibit lipid accumulation in HepG2 cell at the concentration of 50 μMol L.
      • ¥ 3330
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    • Tanshindiol C
      TN509797465-71-9
      Tanshindiol C protects macrophages from oxLDL induced foam cell formation via activation of Prdx1/ABCA1 signaling and that Prdx1 may be a novel target for therapeutic intervention of atherosclerosis.It possesses a unique anti-cancer activity whose mechani
      • ¥ 9980
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