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(S,R,S)-AHPC-C2-amide-benzofuranylmethyl-pyridine 是一种能同时靶向Smad3的泛素化和降解并提高HIF-α蛋白水平的双靶点PROTAC,展现出对肾性贫血的多途径抗纤维化和肾脏保护作用。
(S,R,S)-AHPC-C2-amide-benzofuranylmethyl-pyridine 是一种能同时靶向Smad3的泛素化和降解并提高HIF-α蛋白水平的双靶点PROTAC,展现出对肾性贫血的多途径抗纤维化和肾脏保护作用。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
5 mg | 询价 | 期货 | |
50 mg | 询价 | 期货 |
产品描述 | (S,R,S)-AHPC-C2-amide-benzofuranylmethyl-pyridine is a dual-target PROTAC capable of directing ubiquitination and degradation of Smad3 while also elevating HIF-α protein levels. This compound exhibits both multipath anti-fibrotic and renal protective functions, making it valuable for renal anemia research [1]. |
分子量 | 750.91 |
分子式 | C41H46N6O6S |
CAS No. | 2347517-69-3 |
存储 | Shipping with blue ice. |
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