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The viral main proteinase (M pro , also called 3CL pro ), which controls the activities of the coronavirus replication complex. It functions as a cysteine protease engaging in the proteolytic cleavage of the viral precursor polyprotein to a series of functional proteins required for coronavirus replication and is considered as an appealing target for designing anti-SARS agents. 3CLpro/3C-like Protease Protein, SARS-CoV-2, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 30 kDa and the accession number is P0DTC1.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
10 μg | ¥ 1,470 | 5日内发货 | |
50 μg | ¥ 3,250 | 5日内发货 | |
500 μg | ¥ 23,700 | 5日内发货 | |
1 mg | ¥ 35,600 | 5日内发货 |
生物活性 | Measured by its ability to cleave a fluorogenic peptide substrate, Dabcyl-KTSAVLQSGFRKME-Edans (Synthetic). The specific activity is 136.6pmol/min/μg. (Regularly tested) |
产品描述 | The viral main proteinase (M pro , also called 3CL pro ), which controls the activities of the coronavirus replication complex. It functions as a cysteine protease engaging in the proteolytic cleavage of the viral precursor polyprotein to a series of functional proteins required for coronavirus replication and is considered as an appealing target for designing anti-SARS agents. 3CLpro/3C-like Protease Protein, SARS-CoV-2, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 30 kDa and the accession number is P0DTC1. |
种属 | SARS-CoV-2 |
表达系统 | E. coli |
标签 | Tag Free |
蛋白编号 | P0DTC1 |
别名 | M Proteinase,3C-like Proteinase,3CL Proteinase |
氨基酸序列 | Ser3264-Gln3569 |
蛋白构建 | Ser3264-Gln3569 |
蛋白纯度 | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) |
分子量 | 30 kDa (reducing condition) |
内毒素 | < 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
缓冲液 | Supplied as a 0.2 μm filtered solution of 50 mM Tris-HCl, 1 mM EDTA, pH7.3. |
存储 | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
运输方式 | In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
研究背景 | The viral main proteinase (M pro , also called 3CL pro ), which controls the activities of the coronavirus replication complex. It functions as a cysteine protease engaging in the proteolytic cleavage of the viral precursor polyprotein to a series of functional proteins required for coronavirus replication and is considered as an appealing target for designing anti-SARS agents. |
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