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Search Results for " protease "

Targets Recommended: Protease-activated Receptor HCV Protease HIV Protease Virus Protease Cysteine Protease Protease Serine Protease Protease-activated Receptor

598

抑制剂 & 化合物

68

天然产物

2

化合物库

7

TargetMol 试剂盒

304

重组蛋白

5

同位素标记化合物

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Cat. No.	Product Name
L1100	蛋白酶抑制剂库		343 compounds
	343 种已知的小分子蛋白酶抑制剂的特有集合，可用于高通量筛选和高内涵筛选；
L1710	抗COVID-19化合物库		1133 compounds
	1133 种对SARS-CoV-2有抑制作用或潜在抑制作用的化合物集合，可用于高通量和高内涵筛选；

化合物库

蛋白酶抑制剂库

Cat.No: L1100

Compounds: 343

抗COVID-19化合物库

Cat.No: L1710

Compounds: 1133

Cat. No.	Product Name	Form	Specificity Of Inhibition
C0001	Protease Inhibitor Cocktail (EDTA-Free, 100× in DMSO) 蛋白酶抑制剂 Cocktail (EDTA-Free, 100× in DMSO)	Solution (EDTA-Free,100× in DMSO)	Serine <em>protease</em>s, Aminopeptidases, Cysteine <em>protease</em>s, Aspartic <em>protease</em>s
C0047	RIPA Lysis Buffer (Weak) RIPA裂解液(弱)	Solution in bottle
C0045	RIPA Lysis Buffer (Strong) RIPA裂解液(强)	Solution in bottle
C0046	RIPA Lysis Buffer (Medium) RIPA裂解液(中)	Solution in bottle
C0004	Phosphatase Inhibitor Cocktail III (2 Tubes, 100x) 磷酸酶抑制剂 Cocktail III (2 Tubes, 100x)	2 Tube Solution (100×)	Each Tube has different specificity of inhibition
C0002	Phosphatase Inhibitor Cocktail I (100× ddH2O) 磷酸酶抑制剂 Cocktail I (100× ddH2O)	Solution (100× in ddH2O)	Acid Phosphatase, Alkaline phosphatase, PTPs, ATPases
C0003	Phosphatase Inhibitor Cocktail II (100× DMSO) 磷酸酶抑制剂 Cocktail II (100× DMSO)	Solution (100× in DMSO)	Alkaline phosphatases, Ser/Thr phosphatases, Acid and PP1 and PP2A

TargetMol 试剂盒

蛋白酶抑制剂 Cocktail (EDTA-Free, 100× in DMSO)

Cat.No: C0001

RIPA裂解液(弱)

Cat.No: C0047

RIPA裂解液(强)

Cat.No: C0045

RIPA裂解液(中)

Cat.No: C0046

磷酸酶抑制剂 Cocktail III (2 Tubes, 100x)

Cat.No: C0004

磷酸酶抑制剂 Cocktail I (100× ddH2O)

Cat.No: C0002

磷酸酶抑制剂 Cocktail II (100× DMSO)

Cat.No: C0003

Cat. No.	Product Name	Target	Signaling Pathways
T7740	Protease-Activated Receptor-4 diTFA Protease-Activated Receptor-4 diTFA(245443-52-1(free base))	Protease-activated Receptor	GPCR/G Protein
	Protease-Activated Receptor-4 diTFA 是蛋白酶激活受体 4 (PAR4) 激动剂。
T7513	Protease-Activated Receptor-2, amide 蛋白酶活化的受体-2，酰胺,SLIGKV-NH2,H-丝氨酰亮氨酰异亮氨酰甘氨酰赖氨酰缬氨酰NH2	Protease-activated Receptor	GPCR/G Protein
	Protease-Activated Receptor-2, amide (SLIGKV-NH2) 是 PAR2 的激动剂，IC50为 10.4 M。
T38836L	Protease-Activated Receptor-1, PAR-1 Agonist acetate	Protease-activated Receptor	GPCR/G Protein
	Protease-Activated Receptor-1, PAR-1 Agonist acetate 是一种选择性蛋白酶激活受体 1 (PAR-1) 激动剂肽。它对应于 PAR1 栓系配体，可以选择性地模拟凝血酶通过该受体的作用。
TP1046	SLIGRL-NH2 Protease-Activated Receptor-2 Activating Peptide	Protease-activated Receptor	GPCR/G Protein
	SLIGRL-NH2 (Protease-Activated Receptor-2 Activating Peptide) 为一种蛋白酶激活受体-2 (PAR-2) 激动剂，具有诱导非组胺能性瘙痒的功能。
T39729	HIV Protease Substrate 1
	HIV Protease Substrate 1 is a fluorogenic compound that offers insights into the enzymatic activity of HIV protease, making it a valuable tool for studying this aspect.
T10925L	Cysteine Protease inhibitor hydrochloride Cysteine Protease inhibitor hydrochloride (921625-62-9 free base)	Others	Others
	Cysteine Protease inhibitor hydrochloride 是一种半胱氨酸蛋白酶(cysteine protease)抑制剂。
T10924	Cysteine protease inhibitor-2	Cysteine Protease	Proteases/Proteasome
	Cysteine protease inhibitor-2 是半胱氨酸蛋白酶抑制剂。
T10925	Cysteine Protease inhibitor	Others	Others
	Cysteine protease inhibitors are inhibitors of cysteine proteases. Target: Cysteine Protease
T8936	Proteinase K proteinase K for tritirachium album,Protease K,蛋白酶 K	Others	Others
	Proteinase K (proteinase K for tritirachium album) 是一种非特异性丝氨酸蛋白酶，可用于蛋白消化。它在有 SDS 或尿素存在的情况下，在很大 pH 值 (4-12)、盐浓度和温度单位内均有活性。
T39503	Hepatitis Virus C NS3 Protease Inhibitor 2
	Hepatitis Virus C NS3 Protease Inhibitor 2 is a peptide inhibitor derived from a product that targets the NS3 protease of the hepatitis C virus (HCV). Its inhibitory activity against the NS3 protease is characterized by a Ki value of 41 nM.
T7380	Protease-Activated Receptor-4 蛋白酶活化的受体-4	Protease-activated Receptor	GPCR/G Protein
	Protease-Activated Receptor-4 是蛋白酶激活受体 4 激动剂，具有抗血小板治疗。
T38836	Protease-Activated Receptor-1, PAR-1 Agonist
	Protease-Activated Receptor-1 (PAR-1) Agonist, a selective peptide, activates the PAR-1 receptor by mimicking the specific actions of thrombin. It corresponds to the PAR1 tethered ligand, facilitating selective activation of this receptor.
TQ0129	TNF Protease Inhibitor 2 TAPI-2	MMP	Proteases/Proteasome
	TAPI-2 is a broad-spectrum inhibitor of MMP (IC50: 20 μM), tumour necrosis factorα-converting enzyme (TACE) and a disintegrin and metalloproteinase (ADAM).
T23486	ubiquitin specific protease 3 fragment	Others	Others
	The ubiquitin speci c protease 3 USP3 is a deubiquitinating enzyme for uH2A and uH2B.
T36288	Protease-Activated Receptor-1, PAR-1 Agonist TFA
	Protease-Activated Receptor-1 (PAR-1) Agonist TFA is a selective peptide that acts as an agonist for the proteinase-activated receptor-1 (PAR-1). Corresponding to the tethered ligand of PAR-1, this compound mimics the actions of thrombin through the PAR-1 receptor[1][2].
T76155	Glutamic acid protease	Others	Others
	谷氨酸蛋白酶仅存在于真菌中，为一种含谷氨酸残基的蛋白水解酶。
T36289	Protease-Activated Receptor-3 (PAR-3) (1-6), human TFA
	Protease-Activated Receptor-3 (PAR-3) (1-6), human TFA is a peptide that acts as an agonist for the proteinase-activated receptor (PAR-3)[1].
T76511	HIV Protease Substrate IV
	HIV ProteaseSubstrate IV 是 HIV 蛋白酶的底物。HIV ProteaseSubstrate IV 可用于检测 HIV(人类免疫缺陷病毒)-1 蛋白酶的活性。
T78363	Aspergillopepsin I Aspergillus acid protease	Others	Others
	Aspergillopepsin I (Aspergillus acid protease) 是一种属于天冬氨酸内肽酶类，能广泛特异性催化水解蛋白质中的肽键。
T79277	Cysteine protease inhibitor-3	Parasite	Microbiology/Virology
	Cysteine protease Inhibitor-3 (Compound 15) 是抗疟作用的半胱氨酸蛋白酶抑制剂，能够有效地抑制 Pf3D7、PfW2、PfFP2 和 PfFP3，其 IC50 分别为 0.74 μM、1.05 μM、3.5 μM 和 4.9 μM。该化合物对药物敏感性和耐药性寄生虫均有效。
T76485	HIV Protease Substrate I
	HIV ProteaseSubstrate I 是HIV-1蛋白酶的显色底物。HIV ProteaseSubstrate I 具有HIV 蛋白酶的裂解位点。
T74939	HIV protease-IN-1	Others	Others
	HIVprotease-IN-1 (compound 1·succinate) 是一种有效的HIV 蛋白酶 (HIV protease) 非肽抑制剂，可用于艾滋病的研究。
T36286	Protease-Activated Receptor-3 (PAR-3) (1-6), human
	TFRGAP-amide, human PAR-3-derived tethered ligand sequence which does not activate PAR-3 but rather activates PAR-1 and PAR-2, either in Jurkat or in other PAR-expressing cells.
TP1046L	PAR-2 Activating Peptide acetate SLIGRL-NH2 acetate,PAR-2 Activating Peptide acetate(171436-38-7 free base),Protease-Activated Receptor-2 Activating Peptide acetate	Protease-activated Receptor	GPCR/G Protein
	PAR-2 Activating Peptide acetate (SLIGRL-NH2 acetate)(171436-38-7 free base) 是 Protease-Activated Receptor-2 (PAR-2) 的激动剂。
T80691	β-Herpesvirus protease-IN-1	Virus Protease	Microbiology/Virology
	β-Herpesvirus protease-IN-1 (compound 19)为一种针对β-herpesvirus蛋白酶的抑制剂，其对HCMVPro的IC50值为2.5 μM，而对HHV6Pro的IC50值则为0.33 μM。
T79493	HIV-1 protease-IN-10	PKC	Chromatin/Epigenetic; Cytoskeletal Signaling
	HIV-1protease-IN-10（化合物2）显示出对HIV-1潜伏期的逆转活性，IC50值为0.22 μM。该化合物通过与PKCδC1b结构域结合展现活性，IC50值为0.69 μM。此外，HIV-1protease-IN-10对于酯酶介导的水解表现出稳定性。
T76074	HIV Protease Substrate 1 TFA
	HIV ProteaseSubstrate 1 TFA 是一种外源性 HIV 蛋白酶底物，可用于研究 HIV 蛋白酶的酶活性。
T64112	HIV-1 protease-IN-5	Others	Others
	HIV-1 protease-IN-5 是一种 HIV-1 protease 抑制剂 (IC50: 1.64 nM)。HIV-1 protease-IN-5 对野生型和 DRV 耐药型 HIV-1 表现出明显的作用。
T63949	HIV-1 protease-IN-2	Others	Others
	HIV-1 protease-IN-2 是 HIV-1 protease 的有效抑制剂 (IC50: 2.53 nM)。HIV-1 protease-IN-2 对 DRV (达芦那韦)敏感或耐药性 HIV-1 突变体均表现出抗病毒效果。
T63453	HIV-1 protease-IN-1	Others	Others
	HIV-1 protease-IN-1 是 HIV-1 蛋白酶的有效抑制剂 (IC50: 90 pM)。HIV-1 protease-IN-1 对 B-HIV 具有抗病毒活性 (EC50: 89 nM)。HIV-1 protease-IN-1 能够作用于 C-HIV 毒株 ZM246 (EC50: 13.59 nM) 以及 C-HIV 株 Indie (EC50: 8.23 nM)。
T63733	HIV-1 protease-IN-6	Others	Others
	HIV-1 protease-IN-6 (compound 17d) 是 HIV-1 蛋白酶 (HIV-1 protease) 的有效抑制剂 (IC50: 21 pM, Ki: 4.7 pM)。HIV-1 protease-IN-6 对 DRV (darunavir) 耐药病毒突变体具有显著的抗病毒效果 (antiviral activity)，抑制强度甚至超过对野生型病毒。
T78950	HIV-1 protease-IN-8	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	HIV-1protease-IN-8（compound 34b）是一款高效的HIV-1蛋白酶抑制剂，其IC50为0.32 nM。该化合物对野生型HIV-1（HIV-1NL4-3）及耐药变体（HIV-1MDR）的IC50分别为0.29 μM与1.90 μM，表明其对这两种型别均展现出显著的抗病毒效果。
T74488	HIV-1 protease-IN-4	Others	Others
	HIV-1protease-IN-4 (Compound II-22) 是一种有效的HIV-1蛋白酶抑制剂。HIV-1protease-IN-4 是阿扎那韦的前体。HIV-1蛋白酶-IN-4 作为前体，与口服母体活性分子相比，将母体 1 输送到大鼠血浆中的 AUC 高 5 倍，C24 高 67 倍[1]。
T79536	HIV-1 protease-IN-11	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	HIV-1protease-IN-11 (compound 34a) 为一抗HIV-1蛋白酶抑制剂，其IC50值为0.41 nM，并对抗耐药变异表现出显著活性。
T74942	HIV-1 protease-IN-7	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	HIV-1protease-IN-7（化合物 16）作为一种HIV-1蛋白酶抑制剂，具有良好的口服活性，表现出优异的抑制效能（IC50=3.52 nM，EC50=37 nM）。
T79295	HIV-1 protease-IN-9	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	HIV-1protease-IN-9 (compound 5b)为HIV-1蛋白酶抑制剂，具有0.028 nM的Ki值和66.8 nM的IC50，表现出显著的抗病毒活性。
T79537	HIV-1 protease-IN-12	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	HIV-1protease-IN-12 (compound 35b)为HIV-1蛋白酶抑制剂，具有0.51 nM的IC50值，同时对HIV耐药变体也具有抑制作用。
T62507	Protease-Activated Receptor-1 antagonist 1	Others	Others
	Protease-Activated Receptor-1 antagonist 1 (Compound 13) 是一种蛋白酶激活受体 1 (PAR-1) 拮抗剂，通过 FLIPR 技术得到的 IC50 为 3 nM。Protease-Activated Receptor-1 antagonist 1 能够用于研究血栓性心血管、心肌梗塞和外周动脉疾病。
T64285	Protease-Activated Receptor-1 antagonist 2	Others	Others
	Protease-Activated Receptor-1 antagonist 2 是一种选择性的、口服具有活力的蛋白酶激活受体-1 (PAR-1) 拮抗剂 (IC50: 7 nM)。Protease-Activated Receptor-1 antagonist 2 显示出良好的药代动力学特性，能够用于进行心血管疾病 (CVD) 的相关研究（如动脉粥样硬化和再狭窄）。
T63382	Protease-Activated Receptor-1 antagonist 3	Others	Others
	Protease-Activated Receptor-1 antagonist 3 是蛋白酶激活受体 1protease-activated receptor-1 的有效拮抗剂 (IC50: 7 nM)。Protease-Activated Receptor-1 antagonist 3 与 hERG K+通道表现出结合亲和力 (IC50: 9 μM)。
T74266	Protease-Activated Receptor-1 antagonist 2	Others	Others
	Protease-Activated Receptor-1 antagonist 2 是一种选择性蛋白酶激活受体-1 (PAR-1) 拮抗剂，口服活性，IC50值为7 nM。该化合物具有优良的药代动力学特性，适用于心血管疾病 (CVD) 如动脉粥样硬化和再狭窄的研究。
T76502	HIV-1, HIV-2 Protease Substrate
	HIV-1,HIV-2Protease Substrate 是HIV-1，HIV-2蛋白酶的底物。HIV-1和HIV-2蛋白酶底物结合残基有 4 个保守取代残基。
T1307	Carmofur HCFU,卡莫氟	Nucleoside Antimetabolite/Analog; Virus Protease; SARS-CoV; DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology
	Carmofur (HCFU) 是 5-氟尿嘧啶的衍生物，是一种抗肿瘤药物。它是一种酸性神经酰胺酶抑制剂，用于治疗乳腺癌和结直肠癌。它抑制 SARS-CoV-2主要蛋白酶，还抑制 Vero E6 细胞 SARS-CoV-2，EC50为 24.3 μM。
T6327	Tubacin	Virus Protease; HDAC	Chromatin/Epigenetic; DNA Damage/DNA Repair; Microbiology/Virology
	Tubacin 是一种高效、选择性、可逆、可渗透细胞的 HDAC6 抑制剂，IC50 为 4 nM，选择性是 HDAC1 的约 350 倍。
T75902	SLIGRL-NH2 TFA Protease-Activated Receptor-2 Activating Peptide TFA	Others	Others
	SLIGRL-NH2 TFA（Protease-Activated Receptor-2 Activating Peptide TFA）作为PAR-2（蛋白酶激活受体-2）的激动剂，具有高度特异性。
T8350	TPCK	Proteasome	Proteases/Proteasome; Ubiquitination
	TPCK 是丝氨酸蛋白酶抑制剂，通过与 HPV-18 E7 蛋白的视网膜母细胞瘤蛋白 (RB) 结合核心发生反应，并能够消除其 RB 结合能力。将它添加到培养基内，可修饰活角质形成细胞中的 E7 蛋白。
T1883	Des(benzylpyridyl) Atazanavi	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	Des(benzylpyridyl) Atazanavi 是 Atazanavir 的 N-脱烷基代谢物 (M1)，一种 HIV 蛋白酶抑制剂。
T13397	ZINC03129319	Virus Protease	Microbiology/Virology
	ZINC03129319 是有效的登革病毒 NS2B-NS3蛋白酶抑制剂，抑制常数 Ki1和 Ki3分别为 92 μM 和 20 μM。
T13408	ZK824190	Others; Serine Protease	Others; Proteases/Proteasome
	ZK824190 是具有口服活性尿激酶型纤溶酶原激活剂 (uPA) 选择性抑制剂，对 uPA，tPA 和 Plasmin 的IC50分别为 237，1600 和 1850 nM。ZK824190在多发性硬化症中有研究价值。
T2244	ESI-09	cAMP; Virus Protease	GPCR/G Protein; Microbiology/Virology
	ESI-09是一种新型非环状核苷酸EPAC 的拮抗剂，对EPAC1和EPAC2的IC50值分别为3.2和1.4 μM。

化合物

Protease-Activated Receptor-4 diTFA

Cat.No: T7740

Synonym: Protease-Activated Receptor-4 diTFA(245443-52-1(free base))

Target: Protease-activated Receptor

Protease-Activated Receptor-2, amide

Cat.No: T7513

Synonym: 蛋白酶活化的受体-2，酰胺,SLIGKV-NH2,H-丝氨酰亮氨酰异亮氨酰甘氨酰赖氨酰缬氨酰NH2

Target: Protease-activated Receptor

Protease-Activated Receptor-1, PAR-1 Agonist acetate

Cat.No: T38836L

Target: Protease-activated Receptor

Cat.No: TP1046

Synonym: Protease-Activated Receptor-2 Activating Peptide

Target: Protease-activated Receptor

HIV Protease Substrate 1

Cat.No: T39729

Cysteine Protease inhibitor hydrochloride

Cat.No: T10925L

Synonym: Cysteine Protease inhibitor hydrochloride (921625-62-9 free base)

Target: Others

Cysteine protease inhibitor-2

Cat.No: T10924

Target: Cysteine Protease

Cysteine Protease inhibitor

Cat.No: T10925

Target: Others

Cat.No: T8936

Synonym: proteinase K for tritirachium album,Protease K,蛋白酶 K

Target: Others

Hepatitis Virus C NS3 Protease Inhibitor 2

Cat.No: T39503

Protease-Activated Receptor-4

Cat.No: T7380

Synonym: 蛋白酶活化的受体-4

Target: Protease-activated Receptor

Protease-Activated Receptor-1, PAR-1 Agonist

Cat.No: T38836

TNF Protease Inhibitor 2

Cat.No: TQ0129

Synonym: TAPI-2

Target: MMP

ubiquitin specific protease 3 fragment

Cat.No: T23486

Target: Others

Protease-Activated Receptor-1, PAR-1 Agonist TFA

Cat.No: T36288

Glutamic acid protease

Cat.No: T76155

Target: Others

Protease-Activated Receptor-3 (PAR-3) (1-6), human TFA

Cat.No: T36289

HIV Protease Substrate IV

Cat.No: T76511

Aspergillopepsin I

Cat.No: T78363

Synonym: Aspergillus acid protease

Target: Others

Cysteine protease inhibitor-3

Cat.No: T79277

Target: Parasite

HIV Protease Substrate I

Cat.No: T76485

HIV protease-IN-1

Cat.No: T74939

Target: Others

Protease-Activated Receptor-3 (PAR-3) (1-6), human

Cat.No: T36286

PAR-2 Activating Peptide acetate

Cat.No: TP1046L

Synonym: SLIGRL-NH2 acetate,PAR-2 Activating Peptide acetate(171436-38-7 free base),Protease-Activated Receptor-2 Activating Peptide acetate

Target: Protease-activated Receptor

β-Herpesvirus protease-IN-1

Cat.No: T80691

Target: Virus Protease

HIV-1 protease-IN-10

Cat.No: T79493

Target: PKC

HIV Protease Substrate 1 TFA

Cat.No: T76074

HIV-1 protease-IN-5

Cat.No: T64112

Target: Others

HIV-1 protease-IN-2

Cat.No: T63949

Target: Others

HIV-1 protease-IN-1

Cat.No: T63453

Target: Others

HIV-1 protease-IN-6

Cat.No: T63733

Target: Others

HIV-1 protease-IN-8

Cat.No: T78950

Target: HIV Protease

HIV-1 protease-IN-4

Cat.No: T74488

Target: Others

HIV-1 protease-IN-11

Cat.No: T79536

Target: HIV Protease

HIV-1 protease-IN-7

Cat.No: T74942

Target: HIV Protease

HIV-1 protease-IN-9

Cat.No: T79295

Target: HIV Protease

HIV-1 protease-IN-12

Cat.No: T79537

Target: HIV Protease

Protease-Activated Receptor-1 antagonist 1

Cat.No: T62507

Target: Others

Protease-Activated Receptor-1 antagonist 2

Cat.No: T64285

Target: Others

Protease-Activated Receptor-1 antagonist 3

Cat.No: T63382

Target: Others

Protease-Activated Receptor-1 antagonist 2

Cat.No: T74266

Target: Others

HIV-1, HIV-2 Protease Substrate

Cat.No: T76502

Cat.No: T1307

Synonym: HCFU,卡莫氟

Target: Nucleoside Antimetabolite/Analog, Virus Protease, SARS-CoV, DNA/RNA Synthesis

Cat.No: T6327

Target: Virus Protease, HDAC

Cat.No: T75902

Synonym: Protease-Activated Receptor-2 Activating Peptide TFA

Target: Others

Cat.No: T8350

Target: Proteasome

Des(benzylpyridyl) Atazanavi

Cat.No: T1883

Target: HIV Protease

Cat.No: T13397

Target: Virus Protease

Cat.No: T13408

Target: Others, Serine Protease

Cat.No: T2244

Target: cAMP, Virus Protease

Cat. No.	Product Name	Target	Signaling Pathways
T5783	Rosamultin 野蔷薇苷,罗莎白素	Antioxidant; HIV Protease	Microbiology/Virology; oxidation-reduction; Proteases/Proteasome
	Rosamultin 是从Potentilla anserina L 分离的 19 α-羟基型三萜。它抑制 HIV-1 蛋白酶，具有抗氧化、抗炎和镇痛作用。
TN1059	Ganoderic acid B	IL Receptor; HIV Protease; JAK; STAT	Angiogenesis; Chromatin/Epigenetic; Immunology/Inflammation; JAK/STAT signaling; Microbiology/Virology; Proteases/Proteasome; Stem Cells
	Ganoderic acid B 是从灵芝中分离的一种三萜类天然产物。它是端粒酶抑制剂，抑制 Epstein-Barr 病毒抗原的活化。它是 HIV-1 蛋白酶抑制剂。
TMO2787	Anthraquinone dioxoanthracene,Anthradione,anthracenedione,蒽醌	Virus Protease	Microbiology/Virology
	Anthraquinone (Anthradione) 是常用于缓解便秘的草药中的主要活性成分，可用作染料形成前体。
T5666	Dipotassium glycyrrhizinate	Virus Protease	Microbiology/Virology
	Dipotassium glycyrrhizinate 是一种具有抗过敏和抗炎活性的阴离子表面活性剂。
T2741	Glycyrrhizic acid Glycyrrhizin,甘草酸	Virus Protease; Dehydrogenase; MAO	Metabolism; Microbiology/Virology; Neuroscience
	Glycyrrhizic acid (Glycyrrhizin) 是甘草里面的活性成分三萜皂苷，为 HMGB1的拮抗剂，有用于肿瘤、糖尿病等研究的潜力。
T4S1383	Escin IA Aescin IA,Escin IA;Aescin IA,Escin IA	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	Escin IA (Escin IA;Aescin IA);Aescin IA 是从马蹄中七叶树分离出的一种三萜皂苷，抑制HIV-1蛋白酶，IC50值为 35 μM。它具有抗 TNBC 转移活性，其作用机制涉及通过下调 LOXL2 表达抑制上皮-间质转化过程。
T2875	Angelicin Isopsoralen,异补骨脂素	Apoptosis; Virus Protease; Antiviral	Apoptosis; Immunology/Inflammation; Microbiology/Virology
	Angelicin (Isopsoralen) 是一种三环芳烃天然产物，结构上跟补骨脂素有关，具有抗癌、抗炎、抗病毒等活性。
T4S1387	Isoescin IA 七叶皂苷C,异七叶皂苷 IA	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	Isoescin IA 是一种从七叶树种子中分离出来的三萜皂苷。它具有抗HIV-1蛋白酶活性。
T2926	Schizandrin A	P450; Virus Protease; Autophagy	Autophagy; Metabolism; Microbiology/Virology
	Schisandrin A 是一种从东方药物五味子中提取的主要有效成分，抑制 CYP3A 活性，IC50 分别为 6.60 μM 和 Ki 为 5.83 μM。
T0122	Bergenin Cuscutin,Bengenin,岩白菜素	Apoptosis; IL Receptor; Virus Protease; TNF; NF-κB; Antibacterial; NOD; Autophagy; Antifungal	Apoptosis; Autophagy; Immunology/Inflammation; Microbiology/Virology; NF-κB
	Bergenin (Bengenin) 是一种在许多药用植物中发现的多酚，有细胞保护和抗氧化作用。它还具有广泛的保肝、抗炎、抗肿瘤、抗病毒、抗真菌以及免疫调节作用。
T0254	Probucol DH-581,普罗布考	Virus Protease; ABC; Lipid	Membrane transporter/Ion channel; Metabolism; Microbiology/Virology
	Probucol (DH-581) 是一种抗高脂血症药物，可通过增加 LDL 分解代谢率来降低血液中的胆固醇水平。
T0433	Artesunate WR-256283,青蒿琥酯	Virus Protease; Ferroptosis; STAT; Parasite	Apoptosis; JAK/STAT signaling; Microbiology/Virology; Stem Cells
	Artesunate (WR-256283) 是治疗疟疾的青蒿素组药物的一部分。它是青蒿素的半合成衍生物，具有水溶性。
TN2082	Pinostrobin	Beta Amyloid; IL Receptor; Serine/threonin kinase; TNF	Apoptosis; Cell Cycle/Checkpoint; Immunology/Inflammation; Metabolism; Neuroscience
	Pinostrobin 是一种 PCSK9抑制剂，可抑制 PCSK9 的催化活性。它是能够在多种植物中发现的黄酮类化合物，并具有抗氧化，抗炎，抗癌和神经保护作用。它是有前景的胆固醇调节和脂质管理剂。
T5S0689	Demethylwedelolactone 去甲蟛蜞菊内酯,去甲基蟛蜞内酯	Serine Protease	Proteases/Proteasome
	Demethylwedelolactone 是一种分离自 Eclipta alba 中的 coumestan 天然产物。它能抑制乳腺癌细胞的移动和侵袭，是一种有效的trypsin 抑制剂(IC50:3.0 μM)。
T4850	PCL 016 2-吡啶甲酸,2-Picolinic acid	Virus Protease; Endogenous Metabolite	Metabolism; Microbiology/Virology
	PCL 016 (2-Picolinic acid) 是一种局部抗病毒剂，可抑制兔体内的腺病毒复制。
T1717	alpha-Mangostin α-倒捻子素,α-Mangostin,Mangostin	Apoptosis; Virus Protease; Dehydrogenase; Reactive Oxygen Species; Antibacterial; Antifungal	Apoptosis; Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB
	alpha-Mangostin (Mangostin) 是有多种生物活性的膳食呫吨酮。它是一种IDH1突变体的抑制剂，Ki 值为 2.85 μM。
T2A2498	L-Lysine Aminutrin,Lysine Acid,lysine,L-赖氨酸,赖氨酸	Virus Protease; Endogenous Metabolite; Antifection	Metabolism; Microbiology/Virology
	L-Lysine (Aminutrin) 是一种人类必需氨基酸，能增加钙吸收，减少糖尿病相关疾病和改善肠道健康，可用于疱疹的研究。
T6S0095	Genkwanin 7-O-Methylapigenin,Puddumetin,Apigenin 7-methyl ether,芫花素	Virus Protease	Microbiology/Virology
	Genkwanin (Apigenin 7-methyl ether) 是一种O-甲基化黄酮，有抗炎活性，通过被动扩散和多药耐药蛋白介导的外排机制转运。
T8071	L-Lysine hydrochloride 赖氨酸盐酸盐,Lysine hydrochloride,L-赖氨酸盐酸盐	Virus Protease	Microbiology/Virology
	L-Lysine hydrochloride 是一种人类必需氨基酸，能增加钙吸收，减少糖尿病相关疾病和改善肠道健康，可用于疱疹的研究。
T3717	Hinokitiol 4-Isopropyltropolone,桧木醇,β-thujaplicin,β-桧木醇	DNA Methyltransferase; Virus Protease; Estrogen/progestogen Receptor; Nrf2	Chromatin/Epigenetic; Endocrinology/Hormones; Immunology/Inflammation; Microbiology/Virology
	Hinokitiol (4-Isopropyltropolone) 是从日本扁柏中分离到的一种挥发油成分，可抑制紫外线 B 诱导的角质形成细胞凋亡，可调节雌激素受体信号传导并抑制人乳腺癌细胞的增殖。它具有抗感染、抗氧化及抗肿瘤等活性。
T5S1923	Schisandrin C 五味子丙素,Schizandrin-C,Wuweizisu-C	Apoptosis; Others; Virus Protease	Apoptosis; Microbiology/Virology; Others
	Schisandrin C (Wuweizisu-C) 是从五味子中分离得到的一种植物化学木脂素。它具有抗癌、抗炎和抗氧化等多种生物活性，可研究癌症、阿尔茨海默病、肝病。
T2718	Palmatine chloride	Others; Indoleamine 2,3-Dioxygenase (IDO); Aurora Kinase	Cell Cycle/Checkpoint; Chromatin/Epigenetic; Metabolism; Others
	Palmatine chloride 是口服具有活力的不可逆 IDO-1抑制剂。它能够减轻结肠损伤，预防肠道菌群失调和调节色氨酸分解代谢，并改善 DSS 诱发的结肠炎。
T0800	Danthron Dantron,1,8-Dihydroxyanthraquinone,1,8-二羟基蒽醌,丹蒽醌,Chrysazin,Antrapurol	Virus Protease; Antibacterial; AMPK; Autophagy	Autophagy; Chromatin/Epigenetic; Microbiology/Virology; PI3K/Akt/mTOR signaling
	Danthron (Antrapurol) 是一种从中药 rhubarb 中提取的天然产物，可通过激活 AMPK 来调节葡萄糖和脂质代谢。
T6S1315	Oroxylin A 千层纸素A,6-Methoxybaicalein,Baicalein 6-methyl ether	Virus Protease; HIF/HIF Prolyl-Hydroxylase; Autophagy	Autophagy; Chromatin/Epigenetic; Metabolism; Microbiology/Virology
	Oroxylin A (Baicalein 6-methyl ether) 是一种有活性的黄酮，具有较强的抗癌作用。
T5S0802	Palmatine 巴马汀,Berbericinine,Burasaine	Indoleamine 2,3-Dioxygenase (IDO); AChR; AChE; Aurora Kinase	Cell Cycle/Checkpoint; Chromatin/Epigenetic; Metabolism; Neuroscience
	Palmatine (Burasaine) 是口服具有活力的、不可逆IDO-1抑制剂。它可以减轻结肠损伤，预防肠道菌群失调和调节色氨酸分解代谢，从而改善DSS (Dextran Sulphate Sodium Salt) 诱发的结肠炎。它有用于结肠炎的研究潜力。
TN1202	(-)-α-Pinene 左旋-α-蒎烯,左旋-alpha-蒎烯,(1S)-(-)-Alpha-Pinene	Virus Protease; GABA Receptor; Endogenous Metabolite; Antibacterial	Membrane transporter/Ion channel; Metabolism; Microbiology/Virology; Neuroscience
	(-)-α-Pinene ((1S)-(-)-Alpha-Pinene) 是一种单萜类化合物，通过延长 GABAergic 突触传递、作为 GABAA-BZD 受体的部分调节剂并直接与 GABAA 受体的 BZD 结合位点结合来增强 NREMS 的数量而不影响 NREMS 的强度。
T0011	2-Phenylethanol 苯乙醇,Phenethyl alcohol,2-Phenylethyl alcohol,Benzyl carbinol,Phenylethanol,Benzeneethanol	Others; Virus Protease; Antibacterial; Antibiotic	Microbiology/Virology; Others
	2-Phenylethanol (Phenylethanol) 是从玫瑰、风笛、阿勒颇松、桔子花等多种物种中提取得到的一种无色液体。它有一种使人感到愉悦的气味，也是一种从真菌Candida albicans 产生的自体抗生素。它可用作香皂中的防腐剂，也用作香烟添加剂。
T2774	Lycorine hydrochloride 石蒜碱,Licorine hydrochloride,Galanthidine hydrochloride,Narcissine hydrochloride,Lycorine chloride,Amarylline hydrochloride,盐酸石蒜碱	Virus Protease; HCV Protease; Antibacterial; Autophagy	Autophagy; Microbiology/Virology; Proteases/Proteasome
	Lycorine hydrochloride (Narcissine hydrochloride) 是黑色素瘤血管生成抑制剂，是一种来自石蒜的主要活性成分，抑制 Hey1B 细胞的有丝分裂增殖，IC50值为 1.2 μM，具有抗肿瘤活性。
T3759	3,4-Dimethoxycinnamic acid Dimethylcaffeic acid,3,4-二甲氧基肉桂酸,Caffeic acid dimethyl ether,O-Methylferulic acid	Apoptosis; Virus Protease; Reactive Oxygen Species	Apoptosis; Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB
	3,4-Dimethoxycinnamic acid (O-Methylferulic acid) 是从 Securidaca inappendiculata Hassk 中提取和纯化的单体。 3,4-Dimethoxycinnamic acid 通过 ROS 介导的信号通路对 L-02 细胞发挥抗凋亡作用。抗凋亡作用。
T3324	Lycorine Galanthidine,Narcissine,石蒜碱,Amarylline,Belamarine,Licorine,番石榴碱	Apoptosis; Virus Protease; Antibacterial; AChR; Fatty Acid Synthase	Apoptosis; Metabolism; Microbiology/Virology; Neuroscience
	Lycorine (Narcissine) 是从金眼科植物科中提取的一种天然生物碱。它是一种具有口服活性的SCAP 抑制剂，Kd 值 15.24 nM。它也是黑色素瘤血管生成抑制剂，有用于前列腺癌和代谢疾病的研究潜力。
T2732	(-)-Epicatechin gallate 表儿茶素没食子酸酯,(−)-Epicatechin 3-gallate,Epicatechin gallate,(-)-Epicatechin 3-gallate,(-)-Epicatechin 3-O-gallate,ECG	Virus Protease; COX; Autophagy	Autophagy; Immunology/Inflammation; Microbiology/Virology; Neuroscience
	(-)-Epicatechin gallate ((-)-Epicatechin 3-O-gallate) 抑制环加氧酶-1 的IC50值为 7.5 μM。
T5429	Theaflavin 3,3'-digallate 茶黄素-3,3'-双没食子酸,8-Gingerol,TFDG	Virus Protease; Antioxidant; HIV Protease; HSV	Microbiology/Virology; oxidation-reduction; Proteases/Proteasome
	Theaflavin 3,3'-digallate (8-Gingerol) 是一种寨卡病毒蛋白酶抑制剂，IC50为 2.3 μM。它直接与 ZIKVpro 结合并抑制 ZIKV 复制，可抑制 gp41 和 NS2B-3 蛋白酶的活性，并具有抗 HSV 和 HIV-1病毒活性。它是红茶中的主要多酚，有抗肿瘤作用。
TN1262	3-Feruloylquinic acid 3-O-阿魏酰奎尼酸,3-O-Feruloylquinic acid	Proteasome; Antifection	Microbiology/Virology; Proteases/Proteasome; Ubiquitination
	3-O-Feruloylquinic acid is a protease inhibitor, it exerts moderate inhibitory effect against AIV (H5N1) in vitro.
T2S0223	Isosinensetin 异橙黄酮,6-Demethoxynobiletin	Antioxidant; HIV Protease; Antibacterial; P-gp	Membrane transporter/Ion channel; Microbiology/Virology; Neuroscience; oxidation-reduction; Proteases/Proteasome
	Isosinensetin (6-Demethoxynobiletin) 是从青皮中提取的一种甲氧基黄酮，具有抗氧化和抑制 HIV-1 蛋白酶的活性。
T4S0181	Hinokiflavone 日本扁柏黄酮,扁柏双黄酮	MMP; BCL; E1/E2/E3 Enzyme	Apoptosis; Proteases/Proteasome; Ubiquitination
	Hinokiflavone 是pre-mRNA 剪接活性的新型调节剂，通过抑制剪接体装配来阻止pre-mRNA 底物的剪接，特别是阻止 B complex 的形成。它是SUMO protease 蛋白酶抑制剂，能够抑制前哨蛋白特异性蛋白酶 1 的活性。
T19503	Papain	Others; Cysteine Protease	Others; Proteases/Proteasome
	Papain 是一种半胱氨酸蛋白酶，是肽酶 C1 家族中一员，在食品、医药、化妆品、纺织等具有广泛的应用。
T3323	Ursonic Acid CCRIS 7123,NSC4060,熊果酮酸,Prunol,3-Ketoursolic acid,Malol,TOS-BB-0966	Apoptosis; HIV Protease; Endogenous Metabolite	Apoptosis; Metabolism; Microbiology/Virology; Proteases/Proteasome
	Ursonic Acid (TOS-BB-0966) 是一种天然三萜酸，属于熊果烷三萜类，其结构基于五环熊果烷骨架。它具有作为 HIV-1 蛋白酶抑制剂的潜力。
T3S0136	4'-O-Methylbavachalcone O-Methylbroussochalcone B,4'-O-甲基补骨脂查尔酮	SARS-CoV	Microbiology/Virology
	4'-O-Methylbavachalcone (O-Methylbroussochalcone B) 是从补骨脂中分离得到的一种查尔酮，可抑制严重急性呼吸综合征冠状病毒木瓜样蛋白酶的活性，IC50值为 10.1 μM。
T4915	β-Glycerophosphate disodium salt hydrate	Phosphatase; Endogenous Metabolite	Metabolism
	β-Glycerophosphate disodium salt hydrate 是一种磷酸酶抑制剂，是内源性代谢产物的一种。
T2O2730	L-Serine (S)-Serine,L-丝氨酸,丝氨酸,serine,(-)-Serine,(S)-2-Amino-3-hydroxypropanoic acid	Endogenous Metabolite	Metabolism
	L-Serine (serine) 是一种人体非必需氨基酸，它存在于许多蛋白质中，并且在功能上很重要。L-Serine 也存在于丝氨酸蛋白酶类的活性位点，包括胰蛋白酶和凝乳胰蛋白酶。
T6564	Leupeptin Hemisulfate 亮肽素	Serine Protease; Cysteine Protease	Proteases/Proteasome
	Leupeptin hemisulfate 是一种蛋白酶抑制剂，具有细胞膜渗透性、可逆性、竞争性和口服活性。Leupeptin hemisulfate 可以抑制 Cathepsin B、Cathepsin H、Cathepsin L 的活性，阻断两性溶酶体的融合。Leupeptin hemisulfate 还具有抗炎活性。
T2768	Saikosaponin A 柴胡皂苷A,柴胡皂苷 A	NF-κB; Antibacterial; Liver X Receptor	Metabolism; Microbiology/Virology; NF-κB
	Saikosaponin A 是银柴胡中的主要活性成分，有抗炎活性，可上调 LXRα的表达。
T6S0071	Fraxinellone	HIF/HIF Prolyl-Hydroxylase; STAT; PD-1/PD-L1	Apoptosis; Cell Cycle/Checkpoint; Chromatin/Epigenetic; Immunology/Inflammation; JAK/STAT signaling; Metabolism; Stem Cells
	Fraxinellone 是从白鲜的根皮中分离出来的一种天然产物，是PD-L1抑制剂，可抑制HIF-1α蛋白质合成。它通过靶向 PD-L1，有用于癌症免疫的潜力。
TN6872	Trypsin	Protease-activated Receptor	GPCR/G Protein
	Trypsin 是一种可从鱼类分离出的丝氨酸蛋白酶，可水解赖氨酸或精氨酸羧基侧蛋白质。Trypsin 具有抗炎活性，可通过 PDCoV 的 S 糖蛋白与 pAPN 的相互作用诱导 PDCoV 感染的细胞膜融合，可激活 PAR2 和 PAR4，促进细胞增殖和分化。Trypsin 可用于促进伤口愈合和研究神经源性炎症。
TQ0217	Gomisin G 戈米辛G,戈米辛 G	P450; HIV Protease	Metabolism; Microbiology/Virology; Proteases/Proteasome
	Gomisin G 是一种有抗HIV 活性的天然产物。
TN5171	Tricetin	Apoptosis; Others; Nrf2	Apoptosis; Immunology/Inflammation; Others
	Tricetin 是一种从石榴中分离出的类黄酮。Tricetin 是 Keap1-Nrf2 蛋白相互作用（PPI）的强效竞争性抑制剂，通过激活 Nrf2/HO-1 信号通路和阻止线粒体依赖性细胞凋亡通路，保护帕金森病患免受 6-OHDA 诱导的神经毒性的影响。Tricetin 通过 Akt/GSK-1β途径抑制鼻咽癌的迁移和指示性蛋白酶早老素-1（PS-1）表达。Tricetin 抑制由Egr-1介导的氧化LDL 诱导的内皮炎症，保护大鼠软骨细胞免受IL-1β诱导的炎症和细胞凋亡。
T75705	Pepstatin Trifluoroacetate	Others	Others
	Pepstatin (Pepstatin A) Trifluoroacetate 是一种由放线菌产生的特异性天冬氨酸蛋白酶(aspartic proteases)抑制剂，口服活性强。该化合物能有效抑制hemoglobin-pepsin、hemoglobin-proctase、casein-pepsin、casein-proctase、casein-acid protease和hemoglobin-acid protease的活性，其IC50值分别为4.5 nM、6.2 nM、150 nM、290 nM、520 nM和260 nM。此外，对HIV protease也有抑制作用。
TN5675	Ganomycin I
	Ganomycin I inhibits the activity of HIV-1 protease.
TN7388	Ganoderic acid GS-2	Others	Others
	Ganoderic acid GS-2 inhibits the activity of the human immunodeficiency virus-1 (HIV-1) protease.
T5S0983	Absinthin Absinthiin,Absynthin,洋艾素	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	Absinthin (Absynthin) 是结构独特的三萜类化合物，是艾草苦味高的原因。它是苦味受体hTAS2R46的激动剂，它利用 hTAS2R46 介导的受体特异性机制抑制组胺诱导的细胞内 Ca2+升高。
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天然产物

Cat.No: T5783

Synonym: 野蔷薇苷,罗莎白素

Target: Antioxidant, HIV Protease

Ganoderic acid B

Cat.No: TN1059

Target: IL Receptor, HIV Protease, JAK, STAT

Cat.No: TMO2787

Synonym: dioxoanthracene,Anthradione,anthracenedione,蒽醌

Target: Virus Protease

Dipotassium glycyrrhizinate

Cat.No: T5666

Target: Virus Protease

Glycyrrhizic acid

Cat.No: T2741

Synonym: Glycyrrhizin,甘草酸

Target: Virus Protease, Dehydrogenase, MAO

Cat.No: T4S1383

Synonym: Aescin IA,Escin IA;Aescin IA,Escin IA

Target: HIV Protease

Cat.No: T2875

Synonym: Isopsoralen,异补骨脂素

Target: Apoptosis, Virus Protease, Antiviral

Cat.No: T4S1387

Synonym: 七叶皂苷C,异七叶皂苷 IA

Target: HIV Protease

Cat.No: T2926

Target: P450, Virus Protease, Autophagy

Cat.No: T0122

Synonym: Cuscutin,Bengenin,岩白菜素

Target: Apoptosis, IL Receptor, Virus Protease, TNF, NF-κB, Antibacterial, NOD, Autophagy, Antifungal

Cat.No: T0254

Synonym: DH-581,普罗布考

Target: Virus Protease, ABC, Lipid

Cat.No: T0433

Synonym: WR-256283,青蒿琥酯

Target: Virus Protease, Ferroptosis, STAT, Parasite

Cat.No: TN2082

Target: Beta Amyloid, IL Receptor, Serine/threonin kinase, TNF

Demethylwedelolactone

Cat.No: T5S0689

Synonym: 去甲蟛蜞菊内酯,去甲基蟛蜞内酯

Target: Serine Protease

Cat.No: T4850

Synonym: 2-吡啶甲酸,2-Picolinic acid

Target: Virus Protease, Endogenous Metabolite

alpha-Mangostin

Cat.No: T1717

Synonym: α-倒捻子素,α-Mangostin,Mangostin

Target: Apoptosis, Virus Protease, Dehydrogenase, Reactive Oxygen Species, Antibacterial, Antifungal

Cat.No: T2A2498

Synonym: Aminutrin,Lysine Acid,lysine,L-赖氨酸,赖氨酸

Target: Virus Protease, Endogenous Metabolite, Antifection

Cat.No: T6S0095

Synonym: 7-O-Methylapigenin,Puddumetin,Apigenin 7-methyl ether,芫花素

Target: Virus Protease

L-Lysine hydrochloride

Cat.No: T8071

Synonym: 赖氨酸盐酸盐,Lysine hydrochloride,L-赖氨酸盐酸盐

Target: Virus Protease

Cat.No: T3717

Synonym: 4-Isopropyltropolone,桧木醇,β-thujaplicin,β-桧木醇

Target: DNA Methyltransferase, Virus Protease, Estrogen/progestogen Receptor, Nrf2

Cat.No: T5S1923

Synonym: 五味子丙素,Schizandrin-C,Wuweizisu-C

Target: Apoptosis, Others, Virus Protease

Palmatine chloride

Cat.No: T2718

Target: Others, Indoleamine 2,3-Dioxygenase (IDO), Aurora Kinase

Cat.No: T0800

Synonym: Dantron,1,8-Dihydroxyanthraquinone,1,8-二羟基蒽醌,丹蒽醌,Chrysazin,Antrapurol

Target: Virus Protease, Antibacterial, AMPK, Autophagy

Cat.No: T6S1315

Synonym: 千层纸素A,6-Methoxybaicalein,Baicalein 6-methyl ether

Target: Virus Protease, HIF/HIF Prolyl-Hydroxylase, Autophagy

Cat.No: T5S0802

Synonym: 巴马汀,Berbericinine,Burasaine

Target: Indoleamine 2,3-Dioxygenase (IDO), AChR, AChE, Aurora Kinase

Cat.No: TN1202

Synonym: 左旋-α-蒎烯,左旋-alpha-蒎烯,(1S)-(-)-Alpha-Pinene

Target: Virus Protease, GABA Receptor, Endogenous Metabolite, Antibacterial

2-Phenylethanol

Cat.No: T0011

Synonym: 苯乙醇,Phenethyl alcohol,2-Phenylethyl alcohol,Benzyl carbinol,Phenylethanol,Benzeneethanol

Target: Others, Virus Protease, Antibacterial, Antibiotic

Lycorine hydrochloride

Cat.No: T2774

Synonym: 石蒜碱,Licorine hydrochloride,Galanthidine hydrochloride,Narcissine hydrochloride,Lycorine chloride,Amarylline hydrochloride,盐酸石蒜碱

Target: Virus Protease, HCV Protease, Antibacterial, Autophagy

3,4-Dimethoxycinnamic acid

Cat.No: T3759

Synonym: Dimethylcaffeic acid,3,4-二甲氧基肉桂酸,Caffeic acid dimethyl ether,O-Methylferulic acid

Target: Apoptosis, Virus Protease, Reactive Oxygen Species

Cat.No: T3324

Synonym: Galanthidine,Narcissine,石蒜碱,Amarylline,Belamarine,Licorine,番石榴碱

Target: Apoptosis, Virus Protease, Antibacterial, AChR, Fatty Acid Synthase

(-)-Epicatechin gallate

Cat.No: T2732

Synonym: 表儿茶素没食子酸酯,(−)-Epicatechin 3-gallate,Epicatechin gallate,(-)-Epicatechin 3-gallate,(-)-Epicatechin 3-O-gallate,ECG

Target: Virus Protease, COX, Autophagy

Theaflavin 3,3'-digallate

Cat.No: T5429

Synonym: 茶黄素-3,3'-双没食子酸,8-Gingerol,TFDG

Target: Virus Protease, Antioxidant, HIV Protease, HSV

3-Feruloylquinic acid

Cat.No: TN1262

Synonym: 3-O-阿魏酰奎尼酸,3-O-Feruloylquinic acid

Target: Proteasome, Antifection

Cat.No: T2S0223

Synonym: 异橙黄酮,6-Demethoxynobiletin

Target: Antioxidant, HIV Protease, Antibacterial, P-gp

Cat.No: T4S0181

Synonym: 日本扁柏黄酮,扁柏双黄酮

Target: MMP, BCL, E1/E2/E3 Enzyme

Cat.No: T19503

Target: Others, Cysteine Protease

Cat.No: T3323

Synonym: CCRIS 7123,NSC4060,熊果酮酸,Prunol,3-Ketoursolic acid,Malol,TOS-BB-0966

Target: Apoptosis, HIV Protease, Endogenous Metabolite

4'-O-Methylbavachalcone

Cat.No: T3S0136

Synonym: O-Methylbroussochalcone B,4'-O-甲基补骨脂查尔酮

Target: SARS-CoV

β-Glycerophosphate disodium salt hydrate

Cat.No: T4915

Target: Phosphatase, Endogenous Metabolite

Cat.No: T2O2730

Synonym: (S)-Serine,L-丝氨酸,丝氨酸,serine,(-)-Serine,(S)-2-Amino-3-hydroxypropanoic acid

Target: Endogenous Metabolite

Leupeptin Hemisulfate

Cat.No: T6564

Synonym: 亮肽素

Target: Serine Protease, Cysteine Protease

Cat.No: T2768

Synonym: 柴胡皂苷A,柴胡皂苷 A

Target: NF-κB, Antibacterial, Liver X Receptor

Cat.No: T6S0071

Target: HIF/HIF Prolyl-Hydroxylase, STAT, PD-1/PD-L1

Cat.No: TN6872

Target: Protease-activated Receptor

Cat.No: TQ0217

Synonym: 戈米辛G,戈米辛 G

Target: P450, HIV Protease

Cat.No: TN5171

Target: Apoptosis, Others, Nrf2

Pepstatin Trifluoroacetate

Cat.No: T75705

Target: Others

Cat.No: TN5675

Ganoderic acid GS-2

Cat.No: TN7388

Target: Others

Cat.No: T5S0983

Synonym: Absinthiin,Absynthin,洋艾素

Target: HIV Protease

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Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-00717	Protease 7 Protein, E. coli, Recombinant (His) Protease VII,ompT,Omptin,Protease A,Pr...	E. coli	E. coli
	Protease that can cleave T7 RNA polymerase, ferric enterobactin receptor protein (FEP), antimicrobial peptide protamine and other proteins. This protease has a specificity for paired basic residues.
TMPH-03056	Vacuolar protease A Protein, Neosartorya fumigata, Recombinant (His) Vacuolar protease A,Aspartic protease pep2...	Neosartorya fumigata	E. coli
	Vacuolar aspartic endopeptidase which is probably also secreted and contributes to virulence.
TMPY-00541	LON PROTEASE Protein, E. coli, Recombinant (His)	E. coli	E. coli
	Lon protease, an ATP-dependent mitochondrial protease, is important in mitochondrial protein maintenance. Lon protease is a multifunctional enzyme, and its functions include the degradation of damaged proteins and naturally short-lived proteins, ATPase and chaperone-like activities, as well as DNA binding. Lon protease plays a major role in the protein quality control system in mammalian cell mitochondria. It is present in the mitochondrial matrix and degrades oxidized and misfolded proteins, th...
TMPH-00902	Human adenovirus C serotype 5 Protease (His & Myc) Protease,Adenain,Endoprotease,Adenovirus p...	HAdV-5	E. coli
	Human adenovirus C serotype 5 Protease (His & Myc) is expressed in E. coli.
TMPH-00781	IGA1 protease Protein, Haemophilus influenzae, Recombinant (His & Myc) Immunoglobulin A1 protease autotransporter,iga	Haemophilus influenzae	E. coli
	Virulence factor; cleaves host immunoglobulin A producing intact Fc and Fab fragments. IGA1 protease Protein, Haemophilus influenzae, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 43.2 kDa and the accession number is P45385.
TMPH-00680	Protease 7 Protein, E. coli O157:H7, Recombinant (G236K K237G, His & SUMO) Protease A,Omptin,Outer membrane protein 3B,Pro...	E. coli	E. coli
	Protease that can cleave T7 RNA polymerase, ferric enterobactin receptor protein (FEP), antimicrobial peptide protamine and other proteins. This protease has a specificity for paired basic residues.
TMPJ-01431	SARS-CoV-2 Papain-Like Protease Protein PLpro,PL-PRO,pp1a,Replicase polyprotein 1a,Papain-like P...	SARS-CoV-2	E. coli
	Replication of severe acute respiratory syndrome (SARS) coronavirus (SARS-CoV) requires proteolytic processing of the replicase polyprotein by two viral cysteine proteases, a chymotrypsin-like protease (3CLpro) and a papain-like protease (PLpro). These proteases are important targets for development of antiviral drugs that would inhibit viral replication and reduce mortality associated with outbreaks of SARS-CoV. PLpro is a cysteine protease located within the non-structural protein 3 (NS3) sect...
TMPK-01339	3CLpro/3C-like Protease Protein (S144A), SARS-COV-2, Recombinant 3CL-Mpro,M Proteinase,3CL Protease,Mpro	SARS-CoV-2	E. coli
	3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and also releases the key replicative functions of polymerase and helicase. 3CLpro/3C-like Protease Protein (S144A), SARS-COV-2, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 33.78 kDa and the accession number is YP_009725301.1.
TMPK-01346	3CLpro/3C-like Protease Protein (L50F), SARS-COV-2, Recombinant 3CL-Mpro,Mpro,M Proteinase,3CL Protease	SARS-CoV-2	E. coli
	3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and also releases the key replicative functions of polymerase and helicase. 3CLpro/3C-like Protease Protein (L50F), SARS-COV-2, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 33.8kDa and the accession number is YP_009725301.1.
TMPK-01343	3CLpro/3C-like Protease Protein (A191T), SARS-COV-2, Recombinant 3CL-Mpro,M Proteinase,Mpro,3CL Protease	SARS-CoV-2	E. coli
	3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and also releases the key replicative functions of polymerase and helicase. 3CLpro/3C-like Protease Protein (A191T), SARS-COV-2, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 33.8 kDa and the accession number is YP_009725301.1.
TMPH-02895	Serpin A3K Protein, Mouse, Recombinant (His) Contrapsin,SPI-2,Serpina3k,Serine protease inhibito...	Mouse	P. pastoris (Yeast)
	Contrapsin inhibits trypsin-like proteases. Serpin A3K Protein, Mouse, Recombinant (His) is expressed in yeast with C-6xHis tag. The predicted molecular weight is 45.7 kDa and the accession number is P07759.
TMPK-01384	SARS PLpro/papain-like protease Protein (His) Papain-like Protease,PL-PRO,Replicase polyprotein 1...	SARS	E. coli
	The coronaviral proteases, papain-like protease (PLpro) and 3C-like protease (3CLpro), are attractive antiviral drug targets because they are essential for coronaviral replication. Although the primary function of PLpro and 3CLpro are to process the viral polyprotein in a coordinated manner, PLpro has the additional function of stripping ubiquitin and ISG15 from host-cell proteins to aid coronaviruses in their evasion of the host innate immune responses. SARS PLpro/papain-like protease Protein (...
TMPK-01335	3CLpro/3C-like Protease Protein (E166V), SARS-COV-2, Recombinant M Proteinase,Mpro,3CL Protease,3CL-Mpro	SARS-CoV-2	E. coli
	3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and also releases the key replicative functions of polymerase and helicase. 3CLpro/3C-like Protease Protein (E166V), SARS-COV-2, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 33.80 kDa and the accession number is YP_009725301.1.
TMPK-01348	3CLpro/3C-like Protease Protein, SARS-COV-2, Recombinant (aa 1-306) COVID-19,3CL Protease,M Proteinase,3CL Pro,3CL-Mpro...	SARS-CoV-2	E. coli
	3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and also releases the key replicative functions of polymerase and helicase. 3CLpro/3C-like Protease Protein, SARS-COV-2, Recombinant (aa 1-306) is expressed in E. coli expression system. The predicted molecular weight is 33.8 kDa and the accession number is YP_009725301.1.
TMPK-01342	3CLpro/3C-like Protease Protein (A191V), SARS-COV-2, Recombinant Mpro,3CL-Mpro,3CL Protease,M Proteinase	SARS-CoV-2	E. coli
	3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and also releases the key replicative functions of polymerase and helicase. 3CLpro/3C-like Protease Protein (A191V), SARS-COV-2, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 34.8kDa and the accession number is YP_009725301.1.
TMPK-01347	3CLpro/3C-like Protease Protein (E166A), SARS-COV-2, Recombinant 3CL-Mpro,3CL Protease,M Proteinase,Mpro	SARS-CoV-2	E. coli
	3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and also releases the key replicative functions of polymerase and helicase. 3CLpro/3C-like Protease Protein (E166A), SARS-COV-2, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 34.4kDa and the accession number is YP_009725301.1.
TMPK-01336	3CLpro/3C-like Protease Protein (L50F, E166V), SARS-COV-2, Recombinant 3CL-Mpro,3CL Protease,M Proteinase,Mpro	SARS-CoV-2	E. coli
	3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and also releases the key replicative functions of polymerase and helicase. 3CLpro/3C-like Protease Protein (L50F, E166V), SARS-COV-2, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 33.80 kDa and the accession number is YP_009725301.1.
TMPK-01344	3CLpro/3C-like Protease Protein (L167F), SARS-COV-2, Recombinant M Proteinase,Mpro,3CL-Mpro,3CL Protease	SARS-CoV-2	E. coli
	3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and also releases the key replicative functions of polymerase and helicase. 3CLpro/3C-like Protease Protein (L167F), SARS-COV-2, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 34.5kDa and the accession number is YP_009725301.1.
TMPK-01340	3CLpro/3C-like Protease Protein (F140A), SARS-COV-2, Recombinant 3CL-Mpro,3CL Protease,M Proteinase,Mpro	SARS-CoV-2	E. coli
	3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and also releases the key replicative functions of polymerase and helicase. 3CLpro/3C-like Protease Protein (F140A), SARS-COV-2, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 33.72 kDa and the accession number is YP_009725301.1.
TMPK-01337	3CLpro/3C-like Protease Protein (Q189K), SARS-COV-2, Recombinant Mpro,3CL-Mpro,3CL Protease,M Proteinase	SARS-CoV-2	E. coli
	3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and also releases the key replicative functions of polymerase and helicase. 3CLpro/3C-like Protease Protein (Q189K), SARS-COV-2, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 33.79 kDa and the accession number is YP_009725301.1.
TMPK-01338	3CLpro/3C-like Protease Protein (H172Y), SARS-COV-2, Recombinant M Proteinase,3CL-Mpro,Mpro,3CL Protease	SARS-CoV-2	E. coli
	3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and also releases the key replicative functions of polymerase and helicase. 3CLpro/3C-like Protease Protein (H172Y), SARS-COV-2, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 33.82 kDa and the accession number is YP_009725301.1.
TMPK-01341	3CLpro/3C-like Protease Protein (P132H), SARS-COV-2, Recombinant 3CL Protease,3CL-Mpro,Mpro,M Proteinase	SARS-CoV-2	E. coli
	3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and also releases the key replicative functions of polymerase and helicase. 3CLpro/3C-like Protease Protein (P132H), SARS-COV-2, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 33.8 kDa and the accession number is YP_009725301.1.
TMPK-01345	3CLpro/3C-like Protease Protein (L50F, E166A, L167F), SARS-COV-2, Recombinant 3CL-Mpro,Mpro,M Proteinase,3CL Protease	SARS-CoV-2	E. coli
	3CL protease, a viral cysteine proteinase, plays an important role in co-translational proteolytic processing of Coronavirus polyproteins. The 3CL protease cleaves as much as 11 sites in the replicase polyproteins and also releases the key replicative functions of polymerase and helicase. 3CLpro/3C-like Protease Protein (L50F, E166A, L167F), SARS-COV-2, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 34.5 kDa and the accession number is YP_009725301.1.
TMPH-00581	ATP-dependent Clp protease adapter protein ClpS Protein, E. coli, Recombinant (His) yljA,ATP-dependent Clp protease adapter protein Clp...	E. coli	E. coli
	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation. ATP-dependent Clp protease adapter protein ClpS Protein, E. coli, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 16.2?kDa and the accession number is P0A8Q6.
TMPY-01897	PRSS3 Protein, Human, Recombinant (His) PRSS4,TRY4,TRY3,RP11-176F3.3,T9,MTG,protease, serin...	Human	HEK293 Cells
	Trypsin-3, also known as Trypsin III, brain trypsinogen, Serine protease 3 and PRSS3, is a secreted protein that belongs to the peptidase S1 family. Trypsin-3 / PRSS3 is expressed is in pancreas and brain. It contains one peptidase S1 domain. Trypsin-3 / PRSS3 can degrade intrapancreatic trypsin inhibitors that protect against CP. Genetic variants that cause higher mesotrypsin activity might increase the risk for chronic pancreatitis (CP). A sustained imbalance of pancreatic proteases and their ...
TMPK-01352	SARS-CoV-2 PLpro/papain-like protease Protein (His & Avi) Plpro,PL2-PRO,pp1a,nsp1,Replicase polyprotein 1a,Papain-like...	SARS	E. coli
	The coronaviral proteases, papain-like protease (PLpro) and 3C-like protease (3CLpro), are attractive antiviral drug targets because they are essential for coronaviral replication. Although the primary function of PLpro and 3CLpro are to process the viral polyprotein in a coordinated manner, PLpro has the additional function of stripping ubiquitin and ISG15 from host-cell proteins to aid coronaviruses in their evasion of the host innate immune responses. SARS-CoV-2 PLpro/papain-like protease Pro...
TMPH-03329	Mcpt2 Protein, Rat, Recombinant (His & Myc) Mast cell protease 2,Mcpt2,Mast cell protease	Rat	E. coli
	This enzyme, isolated from small intestine, specifically inactivates the apo forms of a certain group of intracellular pyridoxal phosphate-requiring enzymes. It has chymotrypsin-like specificity towards small substrates. Mcpt2 Protein, Rat, Recombinant (His & Myc) is expressed in E. coli expression system with N-6xHis and C-Myc tag. The predicted molecular weight is 30.5 kDa and the accession number is P00770.
TMPH-03176	LasA Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO) lasA,Staphylolytic protease,Protease LasA	Pseudomonas aeruginosa	E. coli
	LasA Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 36.0 kDa and the accession number is P14789.
TMPY-04997	Prostasin/PRSS8 Protein, Rat, Recombinant (His) protease, serine, 8	Rat	HEK293 Cells
	Prostasin/PRSS8 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 32.9 kDa and the accession number is Q9ES87.
TMPH-02236	TMPRSS2 Protein, Human, Recombinant (E. coli, His) Transmembrane protease serine 2,TMPRSS2,Serine ...	Human	E. coli
	Plasma membrane-anchored serine protease that participates in proteolytic cascades of relevance for the normal physiologic function of the prostate. Androgen-induced TMPRSS2 activates several substrates that include pro-hepatocyte growth factor/HGF, the protease activated receptor-2/F2RL1 or matriptase/ST14 leading to extracellular matrix disruption and metastasis of prostate cancer cells. In addition, activates trigeminal neurons and contribute to both spontaneous pain and mechanical allodynia....
TMPH-02237	TMPRSS2 Protein, Human, Recombinant (His & Myc) Serine protease 10,Transmembrane protease ...	Human	HEK293 Cells
	Plasma membrane-anchored serine protease that participates in proteolytic cascades of relevance for the normal physiologic function of the prostate. Androgen-induced TMPRSS2 activates several substrates that include pro-hepatocyte growth factor/HGF, the protease activated receptor-2/F2RL1 or matriptase/ST14 leading to extracellular matrix disruption and metastasis of prostate cancer cells. In addition, activates trigeminal neurons and contribute to both spontaneous pain and mechanical allodynia....
TMPJ-00851	IDE Protein, Human, Recombinant (His) Insulysin,Insulinase,Insulin-Degrading Enzyme,IDE,Abeta-Degr...	Human	HEK293 Cells
	Insulin-Degrading Enzyme (IDE) is a secreted enzyme that belongs to the peptidase M16 family. IDE is a large zinc-binding protease and cleaves multiple short polypeptides that vary considerably in sequence. IDE plays a role in the cellular breakdown of insulin, IAPP, glucagon, bradykinin, kallidin, and other peptides, and thereby plays a role in intercellular peptide signaling. IDE degrades amyloid formed by APP and IAPP. IDE may participate in the degradation and clearance of naturally secreted...
TMPH-03328	Mcpt1 Protein, Rat, Recombinant (Myc) Mast cell protease I,Mcpt1,Chymase,Mast cell pr...	Rat	E. coli
	Major secreted protease of mast cells with suspected roles in vasoactive peptide generation, extracellular matrix degradation, and regulation of gland secretion. May participate in generating perivascular beta-protein which ultimately aggregates into amyloid-beta deposits. Mcpt1 Protein, Rat, Recombinant (Myc) is expressed in E. coli expression system with N-Myc tag. The predicted molecular weight is 28.6 kDa and the accession number is P09650.
TMPH-02239	TMPRSS4 Protein, Human, Recombinant (His & Myc) Channel-activating protease 2,TMPRSS4,Transmembrane...	Human	E. coli
	Plasma membrane-anchored serine protease that directly induces processing of pro-uPA/PLAU into the active form through proteolytic activity. Seems to be capable of activating ENaC.; (Microbial infection) In gut epithelial cells, facilitates human coronavirus SARS-CoV-2 infection through, at least, the cleavage of coronavirus spike glycoproteins which activates the glycoprotein for host cell entry. TMPRSS4 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10...
TMPH-02238	TMPRSS2 Protein, Human, Recombinant (Avi & His & MBP), Biotinylated TMPRSS2,Transmembrane protease serine 2,Serine ...	Human	E. coli
	TMPRSS2 Protein, Human, Recombinant (Avi & His & MBP), Biotinylated is expressed in E. coli expression system with N-MBP and C-6xHis-Avi tag. The predicted molecular weight is 90.6 kDa and the accession number is O15393.
TMPH-02235	TMPRSS2 Protein, Human, Recombinant (Cell-Free, His) Transmembrane protease serine 2,Serine protease...	Human	E. coli
	TMPRSS2 Protein, Human, Recombinant (Cell-Free, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 46.9 kDa and the accession number is O15393.
TMPJ-01295	SENP7 Protein, Human, Recombinant SSP2,KIAA1707,Sentrin-Specific Protease 7,SUSP2,SUM...	Human	E. coli
	Sentrin-Specific Protease 7 (SENP7) acts as a SUMO-2/3-specific protease. SENP7 is likely to regulate the metabolism of poly-SUMO-2/3 rather than SUMO-1 conjugation in vivo. SENP7 has a restricted substrate specificity, and displaying paralogue-specific isopeptidase activity. The C-terminal catalytic domain of SENP7 depolymerized poly-SUMO-2 chains but does not have activity against poly-SUMO-1 chains. SENP7 also had isopeptidase activity against di-SUMO-2- and SUMO-2-modified RanGAP1 (Ran GTPas...
TMPH-02945	TMPRSS4 Protein, Mouse, Recombinant (His & SUMO) Channel-activating protease 4,Transmembrane pro...	Mouse	E. coli
	Plasma membrane-anchored serine protease that directly induces processing of pro-uPA/PLAU into the active form through proteolytic activity. Seems to be capable of activating ENaC. TMPRSS4 Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 57.8 kDa and the accession number is Q8VCA5.
TMPY-00274	Enterokinase Protein, Bovine, Recombinant (His) transmembrane protease, serine 15	Bovine	P. pastoris (Yeast)
	Enterokinase Protein, Bovine, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 27.1 kDa and the accession number is P98072-1.
TMPY-04928	TMPRSS11B Protein, Human, Recombinant (His) transmembrane protease, serine 11B	Human	HEK293 Cells
	TMPRSS11B Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 44.3 kDa and the accession number is CAD91168.1.
TMPH-03330	Mcpt4 Protein, Rat, Recombinant (His & Myc) Mast cell protease IV,Mast cell protease 4...	Rat	E. coli
	N/A. Mcpt4 Protein, Rat, Recombinant (His & Myc) is expressed in E. coli expression system with N-6xHis and C-Myc tag. The predicted molecular weight is 30.5 kDa and the accession number is P97592.
TMPJ-01320	BSSP-4 Protein, Human, Recombinant (His) BSSP4,Tryptase ε,Serine Protease 26,BSSP-4,Serine <...	Human	HEK293 Cells
	Brain-Specific Serine Protease 4 (BSSP-4) is a serine protease that preferentially cleaves the synthetic substrate H-D-Leu-Thr-Arg-pNA compared to tosyl-Gly-Pro-Arg-pNA. BSSP-4 is expressed abundantly in the epithelial cells of the airways, including trachea, esophagus and fetal lung, but scarce in adult lung and expressed at low levels in placenta, pancreas, prostate and thyroid gland. BSSP-4 belongs to the peptidase S1 family and related to trypsin, referentially hydrolyzing substrates after a...
TMPH-03326	MASP2 Protein, Rat, Recombinant (His) Mannan-binding lectin serine protease 2,MBL-associa...	Rat	Baculovirus Insect Cells
	Serum protease that plays an important role in the activation of the complement system via mannose-binding lectin. After activation by auto-catalytic cleavage it cleaves C2 and C4, leading to their activation and to the formation of C3 convertase. MASP2 Protein, Rat, Recombinant (His) is expressed in Baculovirus insect cells with C-6xHis tag. The predicted molecular weight is 79.2 kDa and the accession number is Q9JJS8.
TMPJ-01278	SENP8 Protein, Human, Recombinant (His) DEN1,Protease Cysteine 2,NEDP1,Sentrin-Specific	Human	E. coli
	Sentrin-Specific Protease 8 (SENP8) mediates the reversible covalent modification of proteins by NEDD8. SENP8 catalyzes the full-length NEDD8 to generate its mature form and deconjugation of NEDD8 from targeted proteins such as CUL2 , CUL4A in vivo, or p53. but it does not show activity against ubiquitin or SUMO proteins.
TMPH-02778	Mcpt4 Protein, Mouse, Recombinant (E. coli, His) MSMCP,Mast cell protease 4,Myonase,Serosal mast cel...	Mouse	E. coli
	Has chymotrypsin-like activity. Hydrolyzes the amide bonds of synthetic substrates having Tyr and Phe residues at the P1 position. Preferentially hydrolyzes the 'Tyr-4-\|-Ile-5' bond of angiotensin I and the 'Phe-20-\|-Ala-21' bond of amyloid beta-protein, and is less active towards the 'Phe-8-\|-His-9' bond of angiotensin I and the 'Phe-4-\|-Ala-5' and 'Tyr-10-\|-Glu-11' bonds of amyloid beta-protein. Involved in thrombin regulation and fibronectin processing. Mcpt4 Protein, Mouse, Recombinant (E. c...
TMPH-02408	SPI Protein, Lentinula edodes, Recombinant (His) Serine protease inhibitor	Lentinula edodes	E. coli
	Serine protease inhibitor. Active against beta-trypsin and alpha-chymotrypsin with dissociation constants of 0.35 nM and 40 nM respectively. Inhibits factor XIa, but not other enzymes involved in coagulation and fibrinolysis. Does not inhibit subtilisin, lysyl endopeptidase, arginyl endopeptidase or papain.
TMPJ-01203	HATL5 Protein, Human, Recombinant (His) HATL5,Transmembrane Protease Serine 11B,Airway Tryp...	Human	HEK293 Cells
	Transmembrane Protease Serine 11B (TMPRSS11B) is a single-pass type II membrane protein member of the peptidase S1 family. TMPRSS11B contains one peptidase S1 domain and one SEA domain. TMPRSS11B is a serine protease that may play some biological role in the host defense system on the mucous membrane independently of or in cooperation with other substances in airway mucous or bronchial secretions.
TMPH-03572	SplB Protein, S. aureus, Recombinant (His & Myc) splB,Serine protease SplB	Staphylococcus aureus	E. coli
	Serine protease that cleaves specifically after the sequence Trp-Glu-Leu-Gln. SplB Protein, S. aureus, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 29.8 kDa and the accession number is A7X3Q8.
TMPH-02080	PRSS56 Protein, Human, Recombinant (His & Myc) PRSS56,Serine protease 56	Human	E. coli
	PRSS56 Protein, Human, Recombinant (His & Myc) is expressed in E. coli.
TMPH-03573	SplD Protein, S. aureus, Recombinant (His & Myc) Serine protease SplD,splD	Staphylococcus aureus	E. coli
	SplD Protein, S. aureus, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 29.5 kDa and the accession number is Q2FXC5.
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重组蛋白

Protease 7 Protein, E. coli, Recombinant (His)

Cat.No: TMPH-00717

Species: E. coli

Expression System: E. coli

Vacuolar protease A Protein, Neosartorya fumigata, Recombinant (His)

Cat.No: TMPH-03056

Species: Neosartorya fumigata

Expression System: E. coli

LON PROTEASE Protein, E. coli, Recombinant (His)

Cat.No: TMPY-00541

Species: E. coli

Expression System: E. coli

Human adenovirus C serotype 5 Protease (His & Myc)

Cat.No: TMPH-00902

Species: HAdV-5

Expression System: E. coli

IGA1 protease Protein, Haemophilus influenzae, Recombinant (His & Myc)

Cat.No: TMPH-00781

Species: Haemophilus influenzae

Expression System: E. coli

Protease 7 Protein, E. coli O157:H7, Recombinant (G236K K237G, His & SUMO)

Cat.No: TMPH-00680

Species: E. coli

Expression System: E. coli

SARS-CoV-2 Papain-Like Protease Protein

Cat.No: TMPJ-01431

Species: SARS-CoV-2

Expression System: E. coli

3CLpro/3C-like Protease Protein (S144A), SARS-COV-2, Recombinant

Cat.No: TMPK-01339

Species: SARS-CoV-2

Expression System: E. coli

3CLpro/3C-like Protease Protein (L50F), SARS-COV-2, Recombinant

Cat.No: TMPK-01346

Species: SARS-CoV-2

Expression System: E. coli

3CLpro/3C-like Protease Protein (A191T), SARS-COV-2, Recombinant

Cat.No: TMPK-01343

Species: SARS-CoV-2

Expression System: E. coli

Serpin A3K Protein, Mouse, Recombinant (His)

Cat.No: TMPH-02895

Species: Mouse

Expression System: P. pastoris (Yeast)

SARS PLpro/papain-like protease Protein (His)

Cat.No: TMPK-01384

Species: SARS

Expression System: E. coli

3CLpro/3C-like Protease Protein (E166V), SARS-COV-2, Recombinant

Cat.No: TMPK-01335

Species: SARS-CoV-2

Expression System: E. coli

3CLpro/3C-like Protease Protein, SARS-COV-2, Recombinant (aa 1-306)

Cat.No: TMPK-01348

Species: SARS-CoV-2

Expression System: E. coli

3CLpro/3C-like Protease Protein (A191V), SARS-COV-2, Recombinant

Cat.No: TMPK-01342

Species: SARS-CoV-2

Expression System: E. coli

3CLpro/3C-like Protease Protein (E166A), SARS-COV-2, Recombinant

Cat.No: TMPK-01347

Species: SARS-CoV-2

Expression System: E. coli

3CLpro/3C-like Protease Protein (L50F, E166V), SARS-COV-2, Recombinant

Cat.No: TMPK-01336

Species: SARS-CoV-2

Expression System: E. coli

3CLpro/3C-like Protease Protein (L167F), SARS-COV-2, Recombinant

Cat.No: TMPK-01344

Species: SARS-CoV-2

Expression System: E. coli

3CLpro/3C-like Protease Protein (F140A), SARS-COV-2, Recombinant

Cat.No: TMPK-01340

Species: SARS-CoV-2

Expression System: E. coli

3CLpro/3C-like Protease Protein (Q189K), SARS-COV-2, Recombinant

Cat.No: TMPK-01337

Species: SARS-CoV-2

Expression System: E. coli

3CLpro/3C-like Protease Protein (H172Y), SARS-COV-2, Recombinant

Cat.No: TMPK-01338

Species: SARS-CoV-2

Expression System: E. coli

3CLpro/3C-like Protease Protein (P132H), SARS-COV-2, Recombinant

Cat.No: TMPK-01341

Species: SARS-CoV-2

Expression System: E. coli

3CLpro/3C-like Protease Protein (L50F, E166A, L167F), SARS-COV-2, Recombinant

Cat.No: TMPK-01345

Species: SARS-CoV-2

Expression System: E. coli

ATP-dependent Clp protease adapter protein ClpS Protein, E. coli, Recombinant (His)

Cat.No: TMPH-00581

Species: E. coli

Expression System: E. coli

PRSS3 Protein, Human, Recombinant (His)

Cat.No: TMPY-01897

Species: Human

Expression System: HEK293 Cells

SARS-CoV-2 PLpro/papain-like protease Protein (His & Avi)

Cat.No: TMPK-01352

Species: SARS

Expression System: E. coli

Mcpt2 Protein, Rat, Recombinant (His & Myc)

Cat.No: TMPH-03329

Species: Rat

Expression System: E. coli

LasA Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO)

Cat.No: TMPH-03176

Species: Pseudomonas aeruginosa

Expression System: E. coli

Prostasin/PRSS8 Protein, Rat, Recombinant (His)

Cat.No: TMPY-04997

Species: Rat

Expression System: HEK293 Cells

TMPRSS2 Protein, Human, Recombinant (E. coli, His)

Cat.No: TMPH-02236

Species: Human

Expression System: E. coli

TMPRSS2 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-02237

Species: Human

Expression System: HEK293 Cells

IDE Protein, Human, Recombinant (His)

Cat.No: TMPJ-00851

Species: Human

Expression System: HEK293 Cells

Mcpt1 Protein, Rat, Recombinant (Myc)

Cat.No: TMPH-03328

Species: Rat

Expression System: E. coli

TMPRSS4 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-02239

Species: Human

Expression System: E. coli

TMPRSS2 Protein, Human, Recombinant (Avi & His & MBP), Biotinylated

Cat.No: TMPH-02238

Species: Human

Expression System: E. coli

TMPRSS2 Protein, Human, Recombinant (Cell-Free, His)

Cat.No: TMPH-02235

Species: Human

Expression System: E. coli

SENP7 Protein, Human, Recombinant

Cat.No: TMPJ-01295

Species: Human

Expression System: E. coli

TMPRSS4 Protein, Mouse, Recombinant (His & SUMO)

Cat.No: TMPH-02945

Species: Mouse

Expression System: E. coli

Enterokinase Protein, Bovine, Recombinant (His)

Cat.No: TMPY-00274

Species: Bovine

Expression System: P. pastoris (Yeast)

TMPRSS11B Protein, Human, Recombinant (His)

Cat.No: TMPY-04928

Species: Human

Expression System: HEK293 Cells

Mcpt4 Protein, Rat, Recombinant (His & Myc)

Cat.No: TMPH-03330

Species: Rat

Expression System: E. coli

BSSP-4 Protein, Human, Recombinant (His)

Cat.No: TMPJ-01320

Species: Human

Expression System: HEK293 Cells

MASP2 Protein, Rat, Recombinant (His)

Cat.No: TMPH-03326

Species: Rat

Expression System: Baculovirus Insect Cells

SENP8 Protein, Human, Recombinant (His)

Cat.No: TMPJ-01278

Species: Human

Expression System: E. coli

Mcpt4 Protein, Mouse, Recombinant (E. coli, His)

Cat.No: TMPH-02778

Species: Mouse

Expression System: E. coli

SPI Protein, Lentinula edodes, Recombinant (His)

Cat.No: TMPH-02408

Species: Lentinula edodes

Expression System: E. coli

HATL5 Protein, Human, Recombinant (His)

Cat.No: TMPJ-01203

Species: Human

Expression System: HEK293 Cells

SplB Protein, S. aureus, Recombinant (His & Myc)

Cat.No: TMPH-03572

Species: Staphylococcus aureus

Expression System: E. coli

PRSS56 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-02080

Species: Human

Expression System: E. coli

SplD Protein, S. aureus, Recombinant (His & Myc)

Cat.No: TMPH-03573

Species: Staphylococcus aureus

Expression System: E. coli

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Cat. No.	Product Name	Target	Signaling Pathways
T27097	CTP518 CTP 518,Deuterated Atazanivir-D3-1,CTP-518
	CTP518, a deuterated Atazanivir derivative, is a HIV protease inhibitor.
TMID-0082	Lopinavir-d8
	Lopinavir-d8 是 Lopinavir 的氘代化合物。Lopinavir 的 CAS 号为 192725-17-0。Lopinavir 是一种选择性肽模拟 HIV-1 蛋白酶的高效抑制剂。它通过阻止 HIV-1 的成熟而起作用，从而阻断其感染性。它也是SARS-CoV 3CLpro的抑制剂。
TMIH-0394	Nirmatrelvir-d9
	Nirmatrelvir-d9 是 Nirmatrelvir 的氘代化合物。Nirmatrelvir 的 CAS 号为 2628280-40-8。PF-07321332 是一种有效的口服活性SARS-CoV 3CLPRO抑制剂，对 SARS-CoV-2 病毒有针对性，可研究 COVID-19。它是一种胰蛋白酶样蛋白酶抑制剂，可抑制气道上皮钠通道功能。
TMIJ-0302	Esomeprazole-d3
	Esomeprazole-d3 是 Esomeprazole 的氘代化合物。Esomeprazole 的 CAS 号为 119141-88-7。Esomeprazole 是奥美拉唑(omeprazole) 的S-异构体，抑制溶酶体半胱氨酸蛋白酶legumain，防止癌症转移。它是一种质子泵抑制剂（PPI）。
T36903	Rasagiline-13C3 (mesylate) Rasagiline-13C3 (mesylate)
	Rasagiline-13C3is intended for use as an internal standard for the quantification of rasagiline by GC- or LC-MS. Rasagiline is an inhibitor of monoamine oxidase B (MAO-B; IC50= 4.43 nM for the rat brain enzyme).1It is selective for MAO-B over MAO-A (IC50= 412 nM for the rat brain enzyme). It inhibits serum and NGF withdrawal-induced apoptosis of PC12 cells when used at concentrations ranging from 0.01 to 100 μM.2Rasagiline inhibits rat brain MAO-Bin vivo(ED50= 0.1 mg/kg).1It reduces cerebral ede...

同位素标记化合物

Cat.No: T27097

Synonym: CTP 518,Deuterated Atazanivir-D3-1,CTP-518

Cat.No: TMID-0082

Nirmatrelvir-d9

Cat.No: TMIH-0394

Esomeprazole-d3

Cat.No: TMIJ-0302

Rasagiline-13C3 (mesylate)

Cat.No: T36903

Synonym: Rasagiline-13C3 (mesylate)

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