|
TMPY-01605
|
STIM1 Protein, Human, Recombinant (His)
stromal interaction molecule 1,TAM1,GOK,STRMK,IMD10...
|
Human
|
HEK293 Cells
|
|
Stromal interaction molecule 1, also known as STIM1 and GOK, is a cell membrane, a single-pass type I membrane protein and a endoplasmic reticulum membrane protein. STIM1 / GOK is ubiquitously expressed in various human primary cells and tumor cell lines. It contains one EF-hand domain and one SAM (sterile alpha motif) domain. STIM1 / GOK plays a role in mediating Ca2+influx following depletion of intracellular Ca2+stores. It acts as Ca2+sensor in the endoplasmic reticulum via its EF-hand domain... |
|
TMPY-00526
|
VTI1A Protein, Human, Recombinant (mFc)
MVti1,Vti1-rp2,VTI1RP2,vesicle transport through interac...
|
Human
|
HEK293 Cells
|
|
VTI1A Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 48.5 kDa and the accession number is Q96AJ9-2. |
|
TMPY-04072
|
VTI1A Protein, Human, Recombinant (His)
Vti1-rp2,MVti1,vesicle transport through interaction
|
Human
|
HEK293 Cells
|
|
VTI1A Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24.2 kDa and the accession number is Q96AJ9-2. |
|
TMPH-02306
|
VTI1B Protein, Human, Recombinant (His & SUMO)
Vti1-rp1,VTI1B,Vesicle transport through interaction
|
Human
|
E. coli
|
|
V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. May be concerned with increased secretion of cytokines associated with cellular senescence. |
|
TMPY-02603
|
STAT6 Protein, Human, Recombinant (His)
STAT6C,IL-4-STAT,STAT6B,signal transducer and activator of t...
|
Human
|
Baculovirus Insect Cells
|
|
Signal transducer and activator of transcription 6 (STAT6) is a transcription factor that is activated by interleukin-4 (IL-4)-induced tyrosine phosphorylation and mediates most of the IL-4-induced gene expression. STAT6 plays a central role in exerting interleukin-4 (IL-4) mediated biological responses and is found to induce the expression of BCL2L1/BCL-XL, which is responsible for the anti-apoptotic activity of IL4. Transcriptional activation by STAT6 requires the interaction with coactivators... |
|
TMPH-02597
|
C1QA Protein, Mouse, Recombinant (His)
Complement C1q subcomponent subunit A,C1QA
|
Mouse
|
P. pastoris (Yeast)
|
|
C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes. |
|
TMPY-01648
|
TREML2 Protein, Human, Recombinant (His)
TLT2,dJ238O23.1,triggering receptor expressed on myeloid cel...
|
Human
|
HEK293 Cells
|
|
Trem-like transcript 2 protein, also known as Triggering receptor expressed on myeloid cells-like protein 2, TREML2 and TLT2, is a single-pass type I membrane protein that contains one Ig-like V-type (immunoglobulin-like) domain. TREML2 is detected in cultured B cells, T cell leukemia and monocyte leukemia. TREML2 is expressed constitutively on CD8 T-cells and induced on CD4 T-cells after activation. TREML2 is a cell surface receptor that may play a role in the innate and adaptive immune respons... |
|
TMPY-03956
|
Fas Ligand Protein, Human, Recombinant (His)
TNLG1A,FASL,FASLG,CD178,CD95-L,APT1LG1,APTL,CD95L,Fas ligand...
|
Human
|
P. pastoris (Yeast)
|
|
Fas Ligand, also known as FASLG and CD95L, is the ligand for FAS. It is a transmembrane protein which binds to TNFRSF6/FAS. Interaction of FAS with fas Ligand is critical in triggering apoptosis of some types of cells such as lymphocytes. Fas Ligand may be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. Fas Ligand Protei... |
|
TMPY-04989
|
Galectin-9 Protein, Human, Recombinant (hFc)
LGALS9A,lectin, galactoside-binding, soluble, 9,HUAT
|
Human
|
HEK293 Cells
|
|
LGALS9 (Galectin 9) is a Protein Coding gene. 6 alternatively spliced human isoforms have been reported. The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. The protein encoded by this gene is an S-type lectin. It is overexpressed in Hodgkin's disease tissue and might participate in the interaction between the H&RS cells with their surrounding cells and might thus play a role in the pathogenesis of this disease and/or i... |
|
TMPJ-00038
|
IL-7 Protein, Mouse, Recombinant (His)
interleukin-7,白介素,IL-7,IL-7 interleukin-7,PBGF,Lymphopoietin...
|
Mouse
|
HEK293 Cells
|
|
Mouse interleukin-7(IL-7) is the member of hemopoietin family which is important to the differentiation, proliferation, and survival of lymphocyte. Mouse IL-7 shares approximately 88% aa sequence identity with rat IL-7 and 58-60% with human, equine, bovine, ovine, porcine, feline and canine IL-7. It is widely expressed in primary and secondary lymphoid tissues cell and stromal epithelial cells of the thymus, bone marrow, and intestines. IL-7 activation of IL-7 R alpha is critical for both T cell... |
|
TMPJ-01466
|
Osteoprotegerin Protein, Human, Recombinant (aa 22-401, His)
OPG,Tumor Necrosis Factor Receptor Superfamily Member 11B,OC...
|
Human
|
HEK293 Cells
|
|
TNFRSF11B is a secreted protein, containing 2 death domains and 4 TNFR-Cys repeats. TNFRSF11B is a decoy receptor for the receptor activator of nuclear factor kappa B ligand (RANKL). By binding RANKL, TNFRSF11B inhibits nuclear kappa B (NF-κB) which is a central and rapid acting transcription factor for immune-related genes, and a key regulator of inflammation, innate immunity, and cell survival and differentiation. TNFRSF11B levels are influenced by voltage-dependent calcium channelsCav1.2. TNF... |
|
TMPY-02115
|
R-Spondin 3/RSPO3 Protein, Human, Recombinant (aa 1-146, His)
CRISTIN1,THSD2,R-spondin 3,PWTSR
|
Human
|
HEK293 Cells
|
|
R-spondin 3 (RSPO3) is a member of the R-Spondin (RSPO) family in vertebrates that activate Wnt/beta-catenin signaling, plays a key role in these processes. The RSPO family of secreted Wnt modulators is involved in development and disease and holds therapeutic promise as stem cell growth factors. The four members have high structural homology. RSPO2 and RSPO3 are more potent than RSPO1, whereas RSPO4 is relatively inactive. All RSPO members require Wnt ligands and LRP6 for activity and amplify s... |
|
TMPJ-01011
|
FGF-9 Protein, Mouse, Recombinant (His)
heparin-binding growth factor-9,GAF,HBGF-9,Glia-activating f...
|
Mouse
|
E. coli
|
|
Fibroblast growth factor-9 (FGF-9) is an approximately 26 kDa secreted glycoprotein of the FGF family. Secreted mouse FGF-9 lacks the N-terminal 1-3 aa and shares >98% sequence identity with rat, human, equine, porcine and bovine FGF-9. FGF-9 plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. In the mouse embryo the location and timing of FGF-9 expression affects development of the skeleton, cerebellum, lungs, heart, v... |
|
TMPY-02245
|
SNAP-25 Protein, Human, Recombinant (His)
synaptosomal-associated protein, 25kDa,SEC9,SNAP,RIC-4,dJ106...
|
Human
|
E. coli
|
|
Synaptosomal-associated protein 25, also known as Super protein, Synaptosomal-associated 25 kDa protein, SNAP25 and SNAP, is a cytoplasm and cell membrane protein that belongs to the SNAP-25 family. SNAP25 / SUP contains 2 t-SNARE coiled-coil homology domains. SNAP25 / SUP is a membrane bound protein anchored to the cytosolic face of membranes via palmitoyl side chains in the middle of the molecule. SNAP25 / SUP protein is a component of the SNARE complex, which is proposed to account for the sp... |
|
TMPY-04396
|
C-ABL/ABL1 Protein, Human, Recombinant (GST)
v-abl,ABL,JTK7,ABL proto-oncogene 1, non-receptor tyrosine k...
|
Human
|
Baculovirus Insect Cells
|
|
c-Abl belongs to the class of tyrosine kinases and is the prototype of a subfamily which includes two members, c-Abl and Arg (Abl-related gene). Both proteins are localized at the cell membrane, actin cytoskeleton and cytosol, and c-Abl is present in the nucleus as well. c-Abl is a non-receptor tyrosine kinase that participates in multiple signaling pathways linking the cell surface, cytoskeleton, and the nucleus. Recent in vitro studies have also linked c-Abl to amyloid-beta-induced toxicity an... |
|
TMPY-00105
|
Recombinant Protein G
|
|
E. coli
|
|
Protein G is a bacterial cell wall protein expressed at the cell surface of certain group C and group G Streptococcal strains.
It has affinity for both Fab- and Fc-fragments of human IgG by independent and separate binding sites. Binding to the Fc region of immunoglobulins from several species by a non-immune mechanism exhibits great affinity for almost all mammalian immunoglobulin G (IgG) classes, including all human IgG subclasses (IgG1, IgG2, IgG3 and IgG4) and also rabbit, mouse, and goat Ig... |
|
TMPH-00758
|
EspK Protein, Mycobacterium tuberculosis, Recombinant (His & Myc)
espK,ESX-1 secretion-associated protein EspK
|
Mycobacterium tuberculosis
|
E. coli
|
|
May act as a chaperone that facilitates EspB secretion through an interaction with EccCb1. |
|
TMPH-01217
|
DSG3 Protein, Human, Recombinant (E. coli, His)
130 kDa pemphigus vulgaris antigen (PVA),CDHF6,DSG3,Cadherin...
|
Human
|
E. coli
|
|
Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. |
|
TMPH-01216
|
DSG1 Protein, Human, Recombinant (His & Myc)
Cadherin family member 4,DGI,Pemphigus foliaceus antigen,CDH...
|
Human
|
E. coli
|
|
Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. |
|
TMPH-01567
|
IZUMO1 Protein, Human, Recombinant (His & Myc)
Izumo sperm-egg fusion protein 1,IZUMO1,Sperm-specific prote...
|
Human
|
E. coli
|
|
Essential sperm cell-surface protein required for fertilization by acting as a ligand for IZUMO1R/JUNO receptor on egg. The IZUMO1:IZUMO1R/JUNO interaction is a necessary adhesion event between sperm and egg that is required for fertilization but is not sufficient for cell fusion. The ligand-receptor interaction probably does not act as a membrane 'fusogen'. |
|
TMPH-02382
|
Lake Victoria marburgvirus (MARV) (strain Angola/2005) Matrix protein VP40 (His & SUMO)
Marburg VP40,VP40,Matrix protein VP40,Membrane-associated pr...
|
MARV
|
E. coli
|
|
Plays an essential role virus particle assembly and budding. Promotes virus assembly and budding by interacting with host proteins of the multivesicular body pathway. The interaction with host E3 ubiquitin ligase SMURF2 facilitates virus budding. The interaction with the nucleocapsid and the plasma membrane may also facilitate virus budding. Specific interactions with membrane-associated GP and VP24 during the budding process may also occur. May play a role in genome replication. |
|
TMPH-00216
|
SVMP Protein, Bothrops jararaca, Recombinant (His & KSI)
Snake venom metalloproteinase,von Willebrand factor-dependen...
|
Bothrops jararaca
|
E. coli
|
|
Metalloproteinase that binds to von Willebrand factor (VWF) and induces its interaction with GPIb (GP1BA), resulting in platelet aggregation. SVMP Protein, Bothrops jararaca, Recombinant (His & KSI) is expressed in E. coli expression system with N-6xHis-KSI tag. The predicted molecular weight is 18.0 kDa and the accession number is P22028. |
|
TMPH-03729
|
Zaire ebolavirus (strain Kikwit-95) VP30 Protein (His)
Transcriptional activator VP30,EbolaVP30,Minor nucleoprotein...
|
ZEBOV
|
E. coli
|
|
Multifunctional protein that acts as a viral transcriptional activator. Promotes read-through of an RNA hairpin in the NP open reading frame to enhance viral transcription. Mechanistically, nonphosphorylated VP30 hexamers form a ternary complex with the viral leader RNA. Clamps the RNA template and the complex VP35-polymerase L together, thereby increasing the polymerase affinity for the RNA template to increase transcription initiation despite the presence of RNA secondary structures. Assists a... |
|
TMPJ-00382
|
P-selectin Protein, Mouse, Recombinant (Avi & His), Biotinylated
PADGEM,CD62 antigen-like family member P,Granule membrane pr...
|
Mouse
|
HEK293 Cells
|
|
P-selectin/CD62P is a single-pass type I membrane protein which is a member of the Selectin family. It consists 768 amino acid (aa). P-selectin is a cell surface glycoprotein expressed by activated platelets and endothelial cells. It induced expression in lung, liver, kidney and heart after endotoxin treatment. Ca2+-dependent receptor for myeloid cells that binds to carbohydrates on neutrophils and monocytes. It mediates the interaction of activated endothelial cells or platelets with leukocytes... |
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TMPH-02536
|
BNIP3 Protein, Mouse, Recombinant (Cell-Free, His)
Bnip3,BCL2/adenovirus E1B 19 kDa protein-interacting protein...
|
Mouse
|
E. coli
|
|
Apoptosis-inducing protein that can overcome BCL2 suppression. May play a role in repartitioning calcium between the two major intracellular calcium stores in association with BCL2. Involved in mitochondrial quality control via its interaction with SPATA18/MIEAP: in response to mitochondrial damage, participates in mitochondrial protein catabolic process (also named MALM) leading to the degradation of damaged proteins inside mitochondria. The physical interaction of SPATA18/MIEAP, BNIP3 and BNIP... |
|
TMPH-01088
|
CBX5 Protein, Human, Recombinant (His & Myc)
HP1 alpha,CBX5,Heterochromatin protein 1 homolog alpha,Chrom...
|
Human
|
E. coli
|
|
Component of heterochromatin that recognizes and binds histone H3 tails methylated at 'Lys-9' (H3K9me), leading to epigenetic repression. In contrast, it is excluded from chromatin when 'Tyr-41' of histone H3 is phosphorylated (H3Y41ph). Can interact with lamin-B receptor (LBR). This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane. Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins. CBX5 Protein... |
|
TMPH-03137
|
PFS230 Protein, Plasmodium falciparum, Recombinant
PFS230,Gametocyte surface protein P230
|
Plasmodium falciparum
|
E. coli
|
|
Gametocyte surface protein required for male/female gamete fusion. Also required for male gamete exflagellation and interaction with erythrocytes. PFS230 Protein, Plasmodium falciparum, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 15.9 kDa and the accession number is P68874. |
|
TMPH-01106
|
CD300LB Protein, Human, Recombinant (His)
CMRF35-like molecule 7,CD300LB,CMRF35A2,CD300b,TREM-5,Leukoc...
|
Human
|
E. coli
|
|
Acts as an activating immune receptor through its interaction with ITAM-bearing adapter TYROBP, and also independently by recruitment of GRB2. CD300LB Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 18.8 kDa and the accession number is A8K4G0. |
|
TMPH-01512
|
HIF1AN Protein, Human, Recombinant (His)
Hypoxia-inducible factor asparagine hydroxylase,Hypoxia-indu...
|
Human
|
P. pastoris (Yeast)
|
|
Hydroxylates HIF-1 alpha at 'Asn-803' in the C-terminal transactivation domain (CAD). Functions as an oxygen sensor and, under normoxic conditions, the hydroxylation prevents interaction of HIF-1 with transcriptional coactivators including Cbp/p300-interacting transactivator. Involved in transcriptional repression through interaction with HIF1A, VHL and histone deacetylases. Hydroxylates specific Asn residues within ankyrin repeat domains (ARD) of NFKB1, NFKBIA, NOTCH1, ASB4, PPP1R12A and severa... |
|
TMPH-02694
|
GNG12 Protein, Mouse, Recombinant (His & Myc)
Gng12,Guanine nucleotide-binding protein G(I)/G(S)/G(O) subu...
|
Mouse
|
E. coli
|
|
Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. |
|
TMPJ-00913
|
MPZ Protein, Human, Recombinant (His)
Myelin Peripheral Protein,Myelin Protein P0,MPZ,Myelin Prote...
|
Human
|
HEK293 Cells
|
|
Myelin Protein P0 (MPZ) is a single-pass type I membrane glycoprotein which belongs to the myelin P0 protein family. MPZ contains one Ig-like V-type (immunoglobulin-like) domain, absent in the central nervous system. MPZ is a major component of the myelin sheath in peripheral nerves. It is postulated that MPZ is a structural element in the formation and stabilisation of peripheral nerve myelin, holding its characteristic coil structure together by the interaction of its positively-charged domain... |
|
TMPH-00756
|
Capsid Protein, Escherichia phage MS2, Recombinant (His & Myc)
CP,Capsid protein,Coat protein
|
Escherichia phage MS2
|
E. coli
|
|
Capsid protein self-assembles to form an icosahedral capsid with a T=3 symmetry, about 26 nm in diameter, and consisting of 89 capsid proteins dimers (178 capsid proteins). Involved in viral genome encapsidation through the interaction between a capsid protein dimer and the multiple packaging signals present in the RNA genome. The capsid contains also 1 copy of the A2 maturation protein.; Acts as a translational repressor of viral replicase synthesis late in infection. This latter function is th... |
|
TMPY-02298
|
ACYP2 Protein, Human, Recombinant (GST)
ACYM,acylphosphatase 2, muscle type,ACYP
|
Human
|
E. coli
|
|
Recent genome-wide association studies have identified genetic variants in ACYP2 and WFS1 that are associated with cisplatin-induced ototoxicity. We sought to explore the role of these genetic susceptibility factors to cisplatin-induced ototoxicity in patients with testicular cancer. Telomere length, as a marker of biological aging, has been reported to influence the risk of several age-related diseases, including ischemic stroke. Recent studies have identified the genetic variant within ACYP2 a... |
|
TMPH-02624
|
Dsg1a Protein, Mouse, Recombinant (His & Myc & SUMO)
Desmoglein-1,DGI,Dsg1a,Dsg1,Desmosomal glycoprotein I,Dsg1-a...
|
Mouse
|
E. coli
|
|
Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. Dsg1a Protein, Mouse, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Myc tag. The predicted molecular weight is 77.2 kDa and the accession number is Q61495. |
|
TMPH-00538
|
Epstein-Barr virus (strain GD1) EBNA3 Protein (His & Myc)
Epstein-Barr nuclear antigen 3A,Epstein-Barr nuclear antigen...
|
EBV
|
E. coli
|
|
Plays an essential role for activation and immortalization of human B-cells. Represses transcription of viral promoters TP1 and Cp through interaction with host RBPJ, and inhibits EBNA2-mediated activation of these promoters. Since Cp is the promoter for all EBNA mRNAs, EBNA3A probably contributes to a negative autoregulatory control loop. |
|
TMPJ-00625
|
Serpin E1 Protein, Mouse, Recombinant (His)
Pai1,Planh1,Plasminogen activator inhibitor 1,Serpin E1,Mr1,...
|
Mouse
|
HEK293 Cells
|
|
Plasminogen activator inhibitor-1 (serpin E1) is a serine protease inhibitor which belongs to the serpin family. Serpin E1 acts as 'bait' for tissue plasminogen activator, urokinase, protein C and matriptase-3/TMPRSS7. Its rapid interaction with PLAT may function as a major control point in the regulation of fibrinolysis. |
|
TMPH-03758
|
TSG101 Protein, Human, Recombinant (His & Myc & SUMO)
Tumor susceptibility gene 101 protein,ESCRT-I complex subuni...
|
Human
|
E. coli
|
|
Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Mediates the association between the ESCRT-0 and ESCRT-I complex. Required for completion of cytokinesis; the function requires CEP55. May be involved in cell growth and differentiation. Acts as a negative growth regulator. Involved in the budding of many viruses through an intera... |
|
TMPK-00993
|
Coagulation Factor III/Tissue Factor Protein, Canine, Recombinant (His)
Thromboplastin,CD142,TF,FLJ17960,TFA,F3,Coagulation Factor I...
|
Canine
|
HEK293 Cells
|
|
Tissue factor (also named Coagulation Factor III) is a cell surface glycoprotein responsible for initiating the extrinsic pathway of coagulation.Tissue factor is the primary cellular initiator of blood coagulation via interaction with coagulation factor VII. Aberrant expression of tissue factor is responsible for thrombosis during septic shock, atherosclerosis and cancer. |
|
TMPH-02252
|
TPM3 Protein, Human, Recombinant (GST)
Gamma-tropomyosin,Tropomyosin alpha-3 chain,Tropomyosin-3,TP...
|
Human
|
E. coli
|
|
Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments. |
|
TMPH-03652
|
Ustilago maydis P6 virus (UmV6) KP6 killer toxin (His)
KP6 killer toxin,Killer protein 6
|
UmV6
|
P. pastoris (Yeast)
|
|
This protein is lethal to sensitive cells of the same or related species. The KP6 alpha subunit is known to recognize some cellular receptors before interaction of the complex with KP6 beta, precipitating cell death. Ustilago maydis P6 virus (UmV6) KP6 killer toxin (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 10.6 kDa and the accession number is P16948. |
|
TMPK-01263
|
B7-H7 Protein, Cynomolgus, Recombinant (His)
B7H7,B7-H7,HHLA2,B7 Homolog 7
|
Cynomolgus
|
HEK293 Cells
|
|
B7-H7, also known as HHLA2 (HERV-H LTR-associating 2), is a member of the B7 family of immune regulatory proteins.Through interaction with TMIGD2, costimulates T-cells in the context of TCR-mediated activation. Enhances T-cell proliferation and cytokine production via an AKT-dependent signaling cascade. |
|
TMPH-00537
|
Epstein-Barr virus (strain B95-8) EBNA3 Protein (His & Myc)
Epstein-Barr nuclear antigen 3,EBNA3,Epstein-Barr nuclear an...
|
EBV
|
E. coli
|
|
Plays an essential role for activation and immortalization of human B-cells. Represses transcription of viral promoters TP1 and Cp through interaction with host RBPJ, and inhibits EBNA2-mediated activation of these promoters. Since Cp is the promoter for all EBNA mRNAs, EBNA3A probably contributes to a negative autoregulatory control loop. |
|
TMPJ-00231
|
LRG1 Protein, Human, Recombinant (hFc & His)
LRG and LRG1,Leucine-rich alpha-2-glycoprotein,Leucine-rich ...
|
Human
|
HEK293 Cells
|
|
LRG1 is a secreted protein and contains eight LRR repeats and one LRRCT domain, It can be expressed during granulocyte differentiation. LRG1 has been shown to be involved in protein-protein interaction, signal transduction, cell adhesion and development. Levels of the LRG protein are markedly elevated in acute appendicitis and therefore could be used as a diagnostic aid. |
|
TMPK-00708
|
TRAIL R1/DR4/TNFRSF10A Protein, Human, Recombinant (hFc)
TRAIL R1,APO2,DR4,CD261,TRAIL-R,TNFRSF10A,MGC9365
|
Human
|
HEK293 Cells
|
|
Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) induces apoptosis selectively via its interaction with the death receptors TRAILR1/DR4 and TRAILR2/DR5 in a wide range of cancers, while sparing normal cells. Despite its tremendous potential for cancer therapeutics, the translation of TRAIL into the clinic has been confounded by TRAIL-resistant cancer populations. |
|
TMPJ-01122
|
KARS Protein, Human, Recombinant (His)
Lysine--tRNA Ligase,Lysyl-tRNA Synthetase,LysRS,KARS,KIAA007...
|
Human
|
HEK293 Cells
|
|
Lysine-tRNA ligase, also known as Lysyl-tRNA synthetase, LysRS, KARS and KIAA0070, belongs to the class-II aminoacyl-tRNA synthetase family. The N-terminal cytoplasmic domain (1-65) is a functional tRNA-binding domain, which is required for nuclear localization, is involved in the interaction with DARS, but has a repulsive role in the binding to EEF1A1. A central domain (208-259) is involved in homodimerization and is required for interaction with HIV-1 GAG and incorporation into virions. KARS c... |
|
TMPH-03587
|
GspB Protein, S. gordonii, Recombinant (GST)
Serine-rich adhesin for platelets,Serine-rich repeat protein...
|
Streptococcus gordonii
|
E. coli
|
|
Plays a role in virulence and host-pathogen interactions. Mediates binding to human platelets via interaction with the human cell surface glycoprotein GP1BA. Plays a positive role in biofilm formation, possibly by self-association via the basic region (BR). GspB Protein, S. gordonii, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 68.5 kDa and the accession number is Q939N5. |
|
TMPH-01984
|
CLECL1P Protein, Human, Recombinant (His & Myc)
Putative C-type lectin-like domain family 1,DC-associated le...
|
Human
|
Baculovirus Insect Cells
|
|
May function in mediating immune cell-cell interactions. May act as a T-cell costimulatory molecule, enhancing anti-CD3-induced proliferation. May play a role in the interaction of dendritic cells with T-cells and the cells of the adaptive immune response. CLECL1P Protein, Human, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 13 kDa and the accession number is Q8IZS7. |
|
TMPH-02888
|
SFRP5 Protein, Mouse, Recombinant (His)
Sfrp5,Secreted frizzled-related protein 5
|
Mouse
|
E. coli
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Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP5 may be involved in determining the polarity of photoreceptor, and perhaps, other cells in the retina. SFRP5 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 37.2 kDa and the accession number is Q9WU66. |
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TMPY-05062
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NRG2 Protein, Human, Recombinant (His)
DON1,HRG2,NTAK
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Human
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HEK293 Cells
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Neuregulin-2 (NRG2) is a novel member of the neuregulin family of growth and differentiation factors. Through interaction with the ErbB family of receptors, neuregulin-2 induces the growth and differentiation of epithelial, neuronal, glial and other types of cells. A mutation in NRG2 disrupted the induction of nitrate-responsive genes after nitrate treatment by an ammonium-independent mechanism. The nitrate content in roots was lower in the mutants than in the wild type, which may have resulted ... |
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TMPH-01776
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HMGN2 Protein, Human, Recombinant (GST)
Non-histone chromosomal protein HMG-17,HMGN2,High mobility g...
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Human
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E. coli
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Binds to the inner side of the nucleosomal DNA thus altering the interaction between the DNA and the histone octamer. May be involved in the process which maintains transcribable genes in a unique chromatin conformation. HMGN2 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 36.4 kDa and the accession number is P05204. |
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