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ALK5-IN-8 is a highly effective inhibitor of TGFβRI (ALK5). It hinders the phosphorylation of ALK5 on downstream signaling proteins (Smad2 or Smad3) by obstructing the interaction between TGFβRI and ligands. Consequently, it disrupts or prevents TGF-β signaling. ALK5-IN-8 shows promise in the study of diverse diseases associated with ALK5-mediated pathways[1].
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ALK5-IN-8 is a highly effective inhibitor of TGFβRI (ALK5). It hinders the phosphorylation of ALK5 on downstream signaling proteins (Smad2 or Smad3) by obstructing the interaction between TGFβRI and ligands. Consequently, it disrupts or prevents TGF-β signaling. ALK5-IN-8 shows promise in the study of diverse diseases associated with ALK5-mediated pathways[1].
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
2 mg | ¥ 1,600 | 5日内发货 | |
5 mg | ¥ 2,710 | 5日内发货 | |
25 mg | ¥ 9,620 | 6-8周 | |
50 mg | ¥ 12,500 | 6-8周 | |
100 mg | ¥ 17,500 | 6-8周 | |
1 mL x 10 mM (in DMSO) | ¥ 2,730 | 5日内发货 |
产品描述 | ALK5-IN-8 is a highly effective inhibitor of TGFβRI (ALK5). It hinders the phosphorylation of ALK5 on downstream signaling proteins (Smad2 or Smad3) by obstructing the interaction between TGFβRI and ligands. Consequently, it disrupts or prevents TGF-β signaling. ALK5-IN-8 shows promise in the study of diverse diseases associated with ALK5-mediated pathways[1]. |
分子量 | 350.35 |
分子式 | C19H15FN4O2 |
CAS No. | 2705900-81-6 |
存储 | Shipping with blue ice. |
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