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SOD1-Derlin-1 inhibitor-1 (SOD1-Derlin-1 Inhibitor 56-20) (compound 56-20) 是 SOD1-Derlin-1相互作用的抑制剂。SOD1-Derlin-1 inhibitor-1 抑制 SOD1G93A-Derlin-1 复合物,IC50值为 7.11 μM。SOD1-Derlin-1 inhibitor-1 可用于肌萎缩性侧索硬化症的研究。
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SOD1-Derlin-1 inhibitor-1 (SOD1-Derlin-1 Inhibitor 56-20) (compound 56-20) 是 SOD1-Derlin-1相互作用的抑制剂。SOD1-Derlin-1 inhibitor-1 抑制 SOD1G93A-Derlin-1 复合物,IC50值为 7.11 μM。SOD1-Derlin-1 inhibitor-1 可用于肌萎缩性侧索硬化症的研究。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
1 mg | ¥ 117 | 现货 | |
5 mg | ¥ 297 | 现货 | |
10 mg | ¥ 497 | 现货 | |
25 mg | ¥ 996 | 现货 | |
50 mg | ¥ 1,490 | 现货 | |
100 mg | ¥ 2,230 | 现货 | |
200 mg | ¥ 3,190 | 现货 |
产品描述 | SOD1-Derlin-1 inhibitor-1 (SOD1-Derlin-1 Inhibitor 56-20) (compound 56-20) is an inhibitor of SOD1-Derlin-1 interaction. SOD1-Derlin-1 inhibitor-1 inhibits SOD1 G93A -Derlin-1 complex with an IC 50 value of 7.11 μM. SOD1-Derlin-1 inhibitor-1 can be used for amyotrophic lateral sclerosis research[1]. |
体外活性 | SOD1-Derlin-1 inhibitor-1(50 μM;16小时)抑制SOD1 G93A-Derlin-1复合体,IC 50 值为7.11 μM [1]。SOD1-Derlin-1 inhibitor-1(250 nM;6小时)优先与SOD1 G93A相互作用,Kd 值为81.1 μM [1]。 |
别名 | SOD1-Derlin-1 Inhibitor 56-20 |
分子量 | 504.2 |
分子式 | C19H12Br2N4OS |
CAS No. | 840461-03-2 |
Smiles | NC=1C=2C(SC1C(NC3=C(Br)C=C(Br)C=C3)=O)=NC(=CC2)C=4C=CC=NC4 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||
溶解度信息 | DMSO: 1 mg/mL (1.98 mM), Sonication is recommended. | ||||||||||
溶液配制表 | |||||||||||
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