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CaMKI (299-320) 是指由钙/钙调蛋白依赖性蛋白激酶 I (Calcium/calmodulin-dependent protein kinase I,CaMKI) 的第 299 至 320 个氨基酸残基构成的肽段。该肽段具有与 Ca2+–CaM 高亲和力 (Kd≤1 nM),能够磷酸化特定底物蛋白以调节其活性。CaMKI (299-320) 包含 CaM 结合域和自我抑制域,可用于研究细胞生理过程,如细胞增殖、分化和凋亡 (apoptosis)。
CaMKI (299-320) 是指由钙/钙调蛋白依赖性蛋白激酶 I (Calcium/calmodulin-dependent protein kinase I,CaMKI) 的第 299 至 320 个氨基酸残基构成的肽段。该肽段具有与 Ca2+–CaM 高亲和力 (Kd≤1 nM),能够磷酸化特定底物蛋白以调节其活性。CaMKI (299-320) 包含 CaM 结合域和自我抑制域,可用于研究细胞生理过程,如细胞增殖、分化和凋亡 (apoptosis)。
规格 | 价格 | 库存 | 数量 |
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10 mg | 询价 | 期货 | |
50 mg | 询价 | 期货 |
产品描述 | CaMKI (299-320) is a peptide representing residues 299-320 of Calcium/calmodulin-dependent protein kinase I (CaMKI). This segment, functioning as a protein kinase, exhibits a strong interaction with Ca 2+ -CAM (K d ≤1 nM), enabling it to phosphorylate specific substrate proteins and regulate their activity. It encompasses both the CAM-binding domain and the self-inhibition domain. CaMKI (299-320) is applicable for researching cellular physiological processes such as proliferation, differentiation, and apoptosis . |
别名 | Calmodulin-Dependent Protein Kinase I (299-320) Binding Domain |
分子量 | 2599.07 |
分子式 | C116H192N38O28S |
CAS No. | 205598-38-5 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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