SORT-PGRN Interaction Inhibitor 2 is a compound that downregulates SORT1 protein expression and enhances extracellular progranulin (PGRN) secretion in various mammalian cell lines, and is utilized in the study of neurological diseases [1].

该化合物SORT-PGRN互作抑制剂2（Compound MPEP）（0-20 μΜ；24小时）作用于哺乳动物细胞系，有效降低SORT1表达并促进细胞外PGRN分泌[1]。