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Tyrosinase-IN-27(compound 6f)是一种酪氨酸酶(TYR)抑制剂,具有IC50为0.88 μM, 能有效静态猝灭TYR活性。该化合物通过与TYR结合,增加其微环境的疏水性,并通过减少α-螺旋的含量来改变酶的二级结构。在食品工业中,Tyrosinase-IN-27被用于抑制莲藕片的褐变现象。
Tyrosinase-IN-27(compound 6f)是一种酪氨酸酶(TYR)抑制剂,具有IC50为0.88 μM, 能有效静态猝灭TYR活性。该化合物通过与TYR结合,增加其微环境的疏水性,并通过减少α-螺旋的含量来改变酶的二级结构。在食品工业中,Tyrosinase-IN-27被用于抑制莲藕片的褐变现象。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
10 mg | 询价 | 10-14周 | |
50 mg | 询价 | 10-14周 |
产品描述 | Tyrosinase-IN-27 (compound 6f), a tyrosinase (TYR) inhibitor with an IC50 of 0.88 μM, binds to TYR, significantly increasing the enzyme's microenvironment hydrophobicity. This interaction alters the secondary structure of TYR, diminishing its α-helix content and effectively inhibiting enzymatic activity. Tyrosinase-IN-27 has practical applications in the food industry, notably in preventing the browning of lotus root slices. [18] [1] |
分子量 | 328.32 |
分子式 | C18H16O6 |
CAS No. | 2966803-96-1 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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