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UNC4976 TFA为CBX7染色质结构域与核酸结合的PAM(正变构调节剂)拟肽。通过拮抗H3K27me3,特异性阻断CBX7对靶基因的募集,同时促进了与DNA和RNA的非特异性结合。
UNC4976 TFA为CBX7染色质结构域与核酸结合的PAM(正变构调节剂)拟肽。通过拮抗H3K27me3,特异性阻断CBX7对靶基因的募集,同时促进了与DNA和RNA的非特异性结合。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
5 mg | 询价 | 期货 | |
50 mg | 询价 | 期货 |
产品描述 | UNC4976 TFA, a positive allosteric modulator (PAM) peptidomimetic of the CBX7 chromodomain, promotes binding to nucleic acids. It concurrently inhibits the H3K27me3-specific recruitment of CBX7 to target genes and enhances non-specific interaction with DNA and RNA [1]. |
分子量 | 961.12 |
分子式 | C49H71F3N6O10 |
存储 | keep away from moisture | Shipping with blue ice. |
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