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TMPY-04552
|
AKT1 Protein, Human, Recombinant (His)
RAC-ALPHA,v-akt murine thymoma viral oncogene homolog 1,RAC,...
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Human
|
Baculovirus Insect Cells
|
|
v-akt murine thymoma viral oncogene homolog 1 (AKT1), or protein kinase B-alpha (PKB-ALPHA) is a serine-threonine protein kinase, belonging to the Protein Kinase Superfamily. AKT1 is a major mediator of the responses to insulin, insulin-like growth factor 1 (IGF1), and glucose. AKT1 also plays a key role in the regulation of both muscle cell hypertrophy and atrophy. AKT1 activity is required for physiologic cardiac growth in response to IGF1 stimulation or exercise training. In contrast, AKT1 ac... |
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TMPJ-01464
|
IL-2 Superkine Protein, Human, Recombinant (L100F, R101D, L105V, I106V, I112F)
TCGF,Aldesleukin,T-Cell Growth Factor,IL-2,Interleukin-2,IL2
|
Human
|
HEK293 Cells
|
|
Interleukin-2(IL-2) is an interleukin, a type of cytokine signaling molecule in the immune system，belongs to the IL-2 family. It is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions that are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine-activated killer cells, monocytes, macrophages... |
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TMPY-00566
|
CCL18 Protein, Human, Recombinant (His)
PARC,CCL18,CKb7,DC-CK1,chemokine (C-C motif) ligand 18,MIP-4...
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Human
|
P. pastoris (Yeast)
|
|
CCL18 is a chemotactic cytokine involved in the pathogenesis and progression of various disorders, including cancer. Proof showed high levels of CCL18 in the serum of epithelial ovarian carcinoma patients suggesting its potential as a circulating biomarker. CCL18 chemokine has an important role in chemokine-mediated tumor metastasis, and may serve as a potential predictor for poor survival outcomes for ovarian cancer. (CCL18) is predominantly secreted by M2-tumor associated macrophages (TAMs) a... |
|
TMPY-00150
|
IGF2/IGF-II Protein, Human, Recombinant
PP9974,胰岛素样生长因子,C11orf43,IGF-II,insulin-like growth factor 2
|
Human
|
P. pastoris (Yeast)
|
|
Insulin-like growth factor 2 (IGF-2/IGF-II) is a member of the insulin family of polypeptide growth factors, which are involved in development and growth. It is an imprinted gene, expressed only from the paternal allele, and epigenetic changes at this locus are associated with Wilms tumor, Beckwith-Wiedemann syndrome, rhabdomyosarcoma, and Silver-Russell syndrome. IGF-2/IGF-II is a mediator of prolactin-induced alveologenesis; prolactin, IGF-2, and cyclin D1, all of which are overexpressed in br... |
|
TMPJ-01467
|
Oncostatin M/OSM Protein, Human, Recombinant (E. coli, His)
Oncostatin-M,OSM
|
Human
|
E. coli
|
|
Oncostatin M (OSM) is a glycoprotein belonging to the interleukin-6 family of cytokines that includes leukemia-inhibitory factor, granulocyte colony-stimulating factor, and interleukin 6. OSM encodes a growth regulator, which Inhibits the proliferation of a number of tumor cell lines. It stimulates proliferation of AIDS-KS cells. OSM regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. OSM is considered as a pleiotropic cytokine that initiates its biological ac... |
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TMPH-02591
|
COL4A3 Protein, Mouse, Recombinant (His & Myc)
Goodpasture antigen,Collagen alpha-3(IV) chain,COL4...
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Mouse
|
E. coli
|
|
Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.; Tumstatin, a cleavage fragment corresponding to the collagen alpha 3(IV) NC1 domain, possesses both anti-angiogenic and anti-tumor cell activity; these two anti-tumor properties may be regulated via RGD-independent ITGB3-mediated mechanisms. |
|
TMPK-00950
|
CDH17 Domain 6-7 Protein, Human, Recombinant (hFc)
HPT-1,P130,MGC138218,LI-cadherin,FLJ26931,cadherin-16,Cdh17,...
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Human
|
HEK293 Cells
|
|
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach. CDH17 Domain 6-7 Protein, Human, Recombinant (hFc) is expre... |
|
TMPK-01223
|
CDH17 Protein, Mouse, Recombinant (His)
CDH16,LI-cadherin,Cdh17,MGC138218,HPT-1,MGC142024,FLJ26931,B...
|
Mouse
|
HEK293 Cells
|
|
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach. CDH17 Protein, Mouse, Recombinant (His) is expressed in HEK... |
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TMPK-00473
|
CDH17 Protein, Rhesus macaque, Recombinant (His)
CDH16,Cdh17,MGC142024,Cadherin-17,cadherin-16,P130,MGC138218...
|
Rhesus
|
HEK293 Cells
|
|
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach. CDH17 Protein, Rhesus macaque, Recombinant (His) is express... |
|
TMPK-00555
|
CDH17 Protein, Cynomolgus, Recombinant (His)
Cdh17,HPT-1,FLJ26931,LI-cadherin,BILL-cadherin,P130,Cadherin...
|
Cynomolgus
|
HEK293 Cells
|
|
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach. CDH17 Protein, Cynomolgus, Recombinant (His) is expressed i... |
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TMPK-00948
|
CDH17 Protein, Human, Recombinant (hFc)
Cdh17,cadherin-16,FLJ26931,Cadherin-17,HPT-1,P130,CDH16,LI-c...
|
Human
|
HEK293 Cells
|
|
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach. CDH17 Protein, Human, Recombinant (hFc) is expressed in HEK... |
|
TMPK-01224
|
CDH17 Protein (Primary Amine Labeling), Mouse, Recombinant (His), Biotinylated
P130,BILL-cadherin,LI-cadherin,MGC138218,FLJ26931,CDH16,Cadh...
|
Mouse
|
HEK293 Cells
|
|
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach. CDH17 Protein (Primary Amine Labeling), Mouse, Recombinant ... |
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TMPK-00949
|
CDH17 Domain 7 Protein, Human, Recombinant (hFc)
CDH16,P130,MGC142024,Cdh17,FLJ26931,Cadherin-17,MGC138218,ca...
|
Human
|
HEK293 Cells
|
|
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach. CDH17 Domain 7 Protein, Human, Recombinant (hFc) is express... |
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TMPK-00953
|
CDH17 Domain 6-7 Protein, Human, Recombinant (mFc)
Cdh17,CDH16,MGC138218,BILL-cadherin,HPT-1,cadherin-16,MGC142...
|
Human
|
HEK293 Cells
|
|
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach. CDH17 Domain 6-7 Protein, Human, Recombinant (mFc) is expre... |
|
TMPK-00952
|
CDH17 Domain 3 & 4 Protein, Human, Recombinant (mFc)
BILL-cadherin,Cadherin-17,LI-cadherin,CDH16,cadherin-16,Cdh1...
|
Human
|
HEK293 Cells
|
|
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach. CDH17 Domain 3 & 4 Protein, Human, Recombinant (mFc) is exp... |
|
TMPK-00947
|
CDH17 Protein, Human, Recombinant (His & Avi), Biotinylated
CDH16,Cdh17,P130,cadherin-16,HPT-1,LI-cadherin,Cadherin-17,B...
|
Human
|
HEK293 Cells
|
|
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach. CDH17 Protein, Human, Recombinant (His & Avi), Biotinylated... |
|
TMPK-00951
|
CDH17 Domain 5-7 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated
FLJ26931,CDH16,LI-cadherin,MGC138218,cadherin-16,Cadherin-17...
|
Human
|
HEK293 Cells
|
|
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach. CDH17 Domain 5-7 Protein (Primary Amine Labeling), Human, R... |
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TMPK-00170
|
CD40 Protein, Human, Recombinant (aa 21-193, His & Avi), Biotinylated
CD40 antigen, TNFRSF5,CD40 molecule,CD40,MGC9013,C...
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Human
|
HEK293 Cells
|
|
CD40 is a costimulatory protein found on antigen presenting cells and is required for their activation. The binding of CD154 (CD40L) on TH cells to CD40 activates antigen presenting cells and induces a variety of downstream effects.CD40 molecule is a potential target for cancer immunotherapy. There are number of completed and ongoing clinical trials where agonistic anti-CD40 monoclonal antibodies are employed to activate an anti-tumor T cell response via activation of dendritic cells. |
|
TMPY-04936
|
BCL2A1 Protein, Human, Recombinant (His)
BFL1,ACC1,ACC-2,GRS,ACC-1,HBPA1,BCL2 related protein A1,BCL2...
|
Human
|
E. coli
|
|
B-cell lymphoma 2-related protein A1 (BCL2A1) is a member of the BCL-2 family of anti-apoptotic proteins that confers resistance to treatment with anti-cancer drugs. Immunohistochemical expression of Wnt11 and BCL2A1 in complete moles and normal villi. Bcl2 family proteins control mitochondrial apoptosis and its members exert critical cell type and differentiation stage-specific functions, acting as barriers against autoimmunity or transformation. Anti-apoptotic Bcl2a1/Bfl1/A1 is frequently der... |
|
TMPY-03416
|
TNFAIP8 Protein, Human, Recombinant (His)
GG2-1,tumor necrosis factor, alpha-induced protein ...
|
Human
|
E. coli
|
|
Tumor necrosis factor (TNF)-alpha-induced protein 8 (TNFAIP8) family is a newly identified protein with vital roles in maintaining immune homeostasis. Tumor necrosis factor-alpha-inducible protein 8 (TNFAIP8) is a TNF-alpha inducible anti-apoptotic protein with multiple roles in tumor growth and survival. by the creation of cellular autophagy events, TNFAIP8 promotes cell survival and drug resistance in prostate cancer cells. TNFAIP8 regulates Hippo pathway through interacting with LATS1 to prom... |
|
TMPH-02590
|
COL4A2 Protein, Mouse, Recombinant (His)
COL4A2,Collagen alpha-2(IV) chain
|
Mouse
|
E. coli
|
|
Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.; Canstatin, a cleavage product corresponding to the collagen alpha 2(IV) NC1 domain, possesses both anti-angiogenic and anti-tumor cell activity. It inhibits proliferation and migration of endothelial cells, reduces mitochondrial membrane potential, and induces apoptosis. Specifically induces Fas-dependent apoptos... |
|
TMPJ-00316
|
BTN3A1 Protein, Human, Recombinant (hFc & Avi), Biotinylated
BTN3A1,BTF5,CD277,Butyrophilin subfamily 3 member A1
|
Human
|
HEK293 Cells
|
|
Butyrophilin Subfamily 3 Member A1 (BTN3A1/CD277) is a type I transmembrane glycoprotein member of the Ig superfamily. It is expressed on a wide variety of immune cells. Similar to BTN3A2 and BTN3A3, BTN3A1 is composed of an extracellular N-terminal IgV and a membraneproximal IgC domain followed by a transmembrane domain and a cytoplasmic tail. These Ig domains are also found in B7 family costimulatory molecules, suggesting structural and functional similarities between the two protein families.... |
|
TMPJ-01252
|
CLEC2D Protein, Mouse, Recombinant (His)
Clec2d,Clr-b,Clrb,Ocil,Osteoclast inhibitory lectin,C-type l...
|
Mouse
|
HEK293 Cells
|
|
C-type lectin domain family 2, member D (CLEC2D) is implicated in the immune response. Sensing tissue damage is an ancient function of immune cells that is central to the regulation of inflammation, tissue repair, and immunity. The C-type lectin receptor Clec2d as a sensor of cell death, which directly detects histones released during necrosis and thus contributes to inflammation and immunopathology. The Clec2d pathway may also be exploited to favor a pro-inflammatory anti-tumor response. And tu... |
|
TMPY-02597
|
IL-37 Protein, Human, Recombinant
FIL1Z,IL-37,白细胞介素,IL37,IL1F7,IL-1RP1,FIL1(ζ),IL1RP1,FIL1,白介素...
|
Human
|
E. coli
|
|
Interleukin 1 family member 7, or interleukin 37 (IL1F7 / IL37 / IL-1H4) is a secretory protein belonging to the Interleukin 1 family. IL-1F7 was localized in human peripheral monocytic cells. It has been localized the expression of IL-1F7b protein in discrete cell populations including plasma cells and tumor cells. These data suggest that IL-1F7 may be involved in immune response, inflammatory diseases, and/or cancer. Through constructing an adenoviral vector that allows high-level expression i... |
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TMPH-01112
|
COL4A1 Protein, Human, Recombinant (GST)
COL4A1,Collagen alpha-1(IV) chain
|
Human
|
E. coli
|
|
Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.; Arresten, comprising the C-terminal NC1 domain, inhibits angiogenesis and tumor formation. The C-terminal half is found to possess the anti-angiogenic activity. Specifically inhibits endothelial cell proliferation, migration and tube formation. COL4A1 Protein, Human, Recombinant (GST) is expressed in E. coli expr... |
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TMPJ-00766
|
ANXA1 Protein, Human, Recombinant
Chromobindin-9,Phospholipase A2 Inhibitory Protein,Annexin-1...
|
Human
|
E. coli
|
|
Annexin A1 is the first characterized member of the annexin family of proteins and is able to bind to cellular membranes in a calcium-dependent manner, promoting membrane fusion and endocytosis. Annexin A1 has anti-inflammatory properties and inhibits phospholipase A2 activity. Annexin A1 also has roles in many diverse cellular functions, such as membrane aggregation, inflammation, phagocytosis, proliferation, apoptosis, and tumorigenesis and cancer development. ANXA1 is strongly expressed on th... |
|
TMPY-00186
|
GHRH Protein, Human, Recombinant (hFc)
GRF,INN,growth hormone releasing hormone,GHRF
|
Human
|
HEK293 Cells
|
|
The role of hypothalamic growth hormone-releasing hormone (GHRH) in the release of growth hormone (GH) from the pituitary is well established. Extra-hypothalamic growth hormone-releasing hormone (GHRH) plays an important role in infertility. Growth hormone releasing hormone (GHRH) has recently been shown to increase the level of gamma-aminobutyric acid (GABA) and activate GABA receptors (GABARs) in the cerebral cortex. GABA is an inhibitory neurotransmitter that can inhibit seizures. GHRH may pl... |
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TMPH-01552
|
IRF1 Protein, Human, Recombinant (GST & His)
IRF1,Interferon regulatory factor 1
|
Human
|
Baculovirus Insect Cells
|
|
Transcriptional regulator which displays a remarkable functional diversity in the regulation of cellular responses. Regulates transcription of IFN and IFN-inducible genes, host response to viral and bacterial infections, regulation of many genes expressed during hematopoiesis, inflammation, immune responses and cell proliferation and differentiation, regulation of the cell cycle and induction of growth arrest and programmed cell death following DNA damage. Stimulates both innate and acquired imm... |
|
TMPJ-00948
|
Endostatin Protein, Mouse, Recombinant (His)
antiangiogenic agent,type XVIII,collagen α-1(XVIII)...
|
Mouse
|
HEK293 Cells
|
|
Endostatin, an endogenous non‑glycosylated inhibitor of endothelial cell proliferation and angiogenesis. It is produced and/or trimmed by metalloproteinases such as MMP‑2 and MMP‑9, and cathepsins S, B and L. The N‑terminal ~27 aa of Endostatin appear to contain the majority of its activity. This region contains zinc binding sites that are thought to be critical for its anti‑endothelial and anti‑tumor effects, as well as multiple cleavage sites that, when used, can modify its activity. Mouse End... |
|
TMPY-01909
|
Elafin Protein, Human, Recombinant (His)
WAP3,ESI,peptidase inhibitor 3,SKALP,cementoin,MGC13613,WFDC...
|
Human
|
HEK293 Cells
|
|
Elafin, also known as Elastase-specific inhibitor, Peptidase inhibitor 3, Protease inhibitor WAP3, Skin-derived antileukoproteinase, WAP four-disulfide core domain protein 14, PI3, WAP3 and WFDC14, is a secreted protein that contains one WAP domain. Elafin / PI3 consists of two domains: the transglutaminase substrate domain (cementoin moiety) and the elastase inhibitor domain. The transglutaminase substrate domain at the N-terminus serves as an anchor to localize elafin covalently to specific si... |
|
TMPJ-00189
|
TIM-3/KIM-3/HAVCR2 Protein, Cynomolgus, Recombinant (His)
HAVCR2,Tim-3,TIM3,T cell immunoglobulin and mucin domain3
|
Cynomolgus
|
HEK293 Cells
|
|
T cell immunoglobulin and mucin domain 3 is a member of the TIM family of immune regulating molecules. Mature cynomolgus TIM3 consists of a 182 amino acid (aa)extracellular domain (ECD), a 21 aa transmembrane segment, and a 78 aa cytoplasmic tail. TIM3 is up-regulated on several populations of activated myeloid cells (macrophage, monocyte, dendritic cell, microglia, mast cell) and T cells (Th1, CD8+, NK, Treg). Its binding to Galectin9 induces a range of immunosuppressive functions which enhance... |
|
TMPY-04984
|
CXCL17 Protein, Human, Recombinant (His)
Dcip1,UNQ473,DMC,VCC1,chemokine (C-X-C motif) ligand 17,VCC-...
|
Human
|
P. pastoris (Yeast)
|
|
Chemokine (C-X-C motif) ligand 17 (CXCL17) is the latest member of the chemokine family. CXCL17 is a potential oncogene and promising therapeutic target, is an independent biomarker of poor prognosis in patients with breast cancer, and can promote proliferation and migration of breast cancer cells in vitro and in vivo. CXCL17 is expressed in a variety of cancers and promotes tumor progression by recruiting myeloid-derived suppressor cells (MDSCs). CXCL17 attenuates IMQ-induced psoriasis-like ski... |
|
TMPY-02084
|
Thioredoxin 2/TRX2 Protein, Human, Recombinant (His)
MT-TRX,RP5-1119A7. 13-005,TRX2,MTRX,thioredoxin 2
|
Human
|
E. coli
|
|
Thioredoxin-2, also known as TXN2, MTRX and TRX2, is a member of the thioredoxin family. Tryparedoxins (TXN) are thioredoxin-related proteins which, as trypanothione:peroxiredoxin oxidoreductases, constitute the trypanothione-dependent antioxidant defense and may also serve as substrates for ribonucleotide reductase in trypanosomatids. Thioredoxin-2 / TXN2 contains one thioredoxin domain. It is widely expressed in adult (at protein level) and fetal tissues. Human Thioredoxin-2 / TXN2 is a small ... |
|
TMPY-00151
|
Alpha SNAP Protein, Human, Recombinant (His)
N-ethylmaleimide-sensitive factor attachment protein, alpha,...
|
Human
|
E. coli
|
|
NAPA (NSF Attachment Protein Alpha) is a Protein Coding gene. This gene encodes a member of the soluble NSF attachment protein (SNAP) family. SNAP proteins play a critical role in the docking and fusion of vesicles to target membranes as part of the 20S NSF-SNAP-SNARE complex. NAPA represents an anti-apoptotic protein that promotes resistance to cisplatin in cancer cells by inducing the degradation of the tumor suppressor p53. NAPA overexpression decreased the ubiquitination and degradation of s... |
|
TMPY-04203
|
RAB1B Protein, Human, Recombinant (hFc)
RAB1B, member RAS oncogene family
|
Human
|
HEK293 Cells
|
|
RAB1B, a member of the RAS oncogene family, was significantly down-regulated in highly metastatic breast cancer cells. Moreover, down-regulation of RAB1B was also found to promote the proliferation and migration of TNBC cells in vitro and in vivo. Mechanistically, loss of RAB1B resulted in elevated expression of TGF-beta receptor 1 (TbetaR1) through decreased degradation of ubiquitin, increased levels of phosphorylated SMAD3 and TGF-beta-induced epithelial-mesenchymal transition (EMT). Furthermo... |
|
TMPY-06983
|
IFN gamma Protein, Human, Recombinant (E. coli)
Interferon Gamma,IFN γ,IFN gamma,IFG,IFI,干扰素,Interferon γ
|
Human
|
E. coli
|
|
IFN gamma, also known as IFNG, is a secreted protein that belongs to the type II interferon family. IFN gamma is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, and by CD4 and CD8 cytotoxic T lymphocyte effector T cells once antigen-specific immunity develops. IFN gamma has antiviral, immunoregulatory, and anti-tumor properties. IFNG, in addition to having antiviral activity, has important immunoregulatory functions, it is a potent activ... |
|
TMPJ-00130
|
SLAMF2 Protein, Human, Recombinant (hFc & His)
Leukocyte antigen MEM-102,CD48 antigen,CD4...
|
Human
|
HEK293 Cells
|
|
CD48 antigen, also known as B-lymphocyte activation marker BLAST-1, BCM1 surface antigen, Leukocyte antigen MEM-102, TCT.1, CD48, BCM1,and BLAST1, CD48 contains one Ig-like C2-type domain and one Ig-like V-type domain, but does not have a transmembrane domain, however, but is held at the cell surface by a GPI anchor via a C-terminal domain which maybe cleaved to yield a soluble form of the receptor. CD48 may facilitate interaction between activated lymphocytes and be involved in regulating T-cel... |
|
TMPY-04550
|
JNK2 Protein, Human, Recombinant (His)
JNK2α,SAPK1a,PRKM9,JNK2β,JNK2,SAPK,JNK2BETA,mitogen-activate...
|
Human
|
Baculovirus Insect Cells
|
|
Mitogen-activated protein kinase 9 (MAPK9), also well known as c-Jun N-terminal kinase (JNK2), is a member of the MAP kinase subfamily belonging to the protein kinase superfamily. MAPK9 responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating some transcription factors, such as c-Jun and ATF2. The crystal structure of human JNK2 complexed with an indazole inhibitor by applying a high-throughput protein engineering and surface-site mutagenesis approach. A n... |
|
TMPH-02317
|
YTHDF1 Protein, Human, Recombinant (His)
YTHDF1,Dermatomyositis associated with cancer putative auto<...
|
Human
|
P. pastoris (Yeast)
|
|
Specifically recognizes and binds N6-methyladenosine (m6A)-containing mRNAs, and regulates their stability. M6A is a modification present at internal sites of mRNAs and some non-coding RNAs and plays a role in mRNA stability and processing. Acts as a regulator of mRNA stability by promoting degradation of m6A-containing mRNAs via interaction with the CCR4-NOT complex. The YTHDF paralogs (YTHDF1, YTHDF2 and YTHDF3) shares m6A-containing mRNAs targets and act redundantly to mediate mRNA degradatio... |
|
TMPY-01824
|
Caspase-14 Protein, Human, Recombinant (His)
caspase 14, apoptosis-related cysteine peptidase,ARCI12
|
Human
|
E. coli
|
|
Caspase 14 is a member of the caspase family. Caspases are a kind of cysteine proteinase consisting of a prodomain plus large and small catalytic subunits, that play a central role in cell apoptosis. Caspase 14 possesses an unusually short prodomain and is highly expressed in embryonic tissues but absent from most of the adult tissues except for the skin, which suggests a role in ontogenesis and skin physiology. Unlike the other short prodomain caspases(caspase-3, caspase-6, and caspase-7), Casp... |
|
TMPJ-00155
|
Mucin-1/MUC1 Protein, Human, Recombinant (hFc&Avi), Biotinylated
Polymorphic epithelial mucin,KL-6,Cancer antigen 15...
|
Human
|
HEK293 Cells
|
|
Mucin-1, is a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. MUC-1 exclusively located in the apical domain of the plasma membrane ... |
|
TMPH-03753
|
MYLK Protein, Human, Recombinant (His)
MYLK,Myosin light chain kinase, smooth muscle,Telokin,Kinase...
|
Human
|
E. coli
|
|
Calcium/calmodulin-dependent myosin light chain kinase implicated in smooth muscle contraction via phosphorylation of myosin light chains (MLC). Also regulates actin-myosin interaction through a non-kinase activity. Phosphorylates PTK2B/PYK2 and myosin light-chains. Involved in the inflammatory response (e.g. apoptosis, vascular permeability, leukocyte diapedesis), cell motility and morphology, airway hyperreactivity and other activities relevant to asthma. Required for tonic airway smooth muscl... |
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