|
TMPH-00792
|
FtnA Protein, Helicobacter pylori, Recombinant (His)
Bacterial non-heme ferritin,ftnA
|
Helicobacter pylori
|
Baculovirus Insect Cells
|
|
Iron-storage protein. |
|
TMPH-00793
|
FtnA Protein, Helicobacter pylori, Recombinant (E. coli, His)
Bacterial non-heme ferritin,ftnA
|
Helicobacter pylori
|
E. coli
|
|
Iron-storage protein. |
|
TMPH-00580
|
Aquaporin Z Protein, E. coli, Recombinant (His)
Water channel AqpZ,bniP,Aquaporin Z,Bacterial nodul...
|
E. coli
|
E. coli
|
|
Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity. Aquaporin Z Protein, E. coli, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 27.7 kDa and the accession number is P60844. |
|
TMPK-01246
|
GDF-15 Protein, Mouse, Recombinant (His)
MIC1,Placental TGF-beta,Placental TGF-β,PTGF-beta,PTGFBPTGF-...
|
Mouse
|
E. coli
|
|
Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and that GDF15 was necessary for surviving both bacterial and viral infections, as well as sepsis. The protective effects of GDF15 were largely independent of pathogen control or the magnitude of inflammatory response, suggesting a role in disease tolerance. GDF-15 Protein, Mouse, Rec... |
|
TMPY-00817
|
Granzyme B/GZMB Protein, Human, Recombinant (His)
CGL1,CTLA1,CSP-B,CTSGL1,HLP,SECT,CSPB,granzyme B (granzyme 2...
|
Human
|
HEK293 Cells
|
|
Granzyme B, also known as GZMB, is the most prominent member of the granzyme family of cell death-inducing serine proteases expressed in the granules of cytotoxic T lymphocytes (CTLs) and NK cells. Granzyme B enters the target cells depending on another membrane-binding granule protein, perforin, results in the activation of effector caspases and mitochondrial depolarization through caspase-dependent and -independent pathways, and consequently induces rapid cell apoptosis. Over 3 substrates of G... |
|
TMPY-01850
|
CEACAM3 Protein, Human, Recombinant (His)
W282,W264,CEA,CD66D,CGM1,MGC119875,carcinoembryonic antigen ...
|
Human
|
HEK293 Cells
|
|
CeACAM3 (CD66d), a member of carcinoembryonic antigen family, is a granulocyte-specific receptor involved in the opsonin-independent recognition of several bacterial pathogens. There are four members in this family: CD66a, CD66b, CD66c, and CD66d. Members of CEACAM family are widely expressed especially on human neutrophils, and, depending on the tissue, capable of regulating diverse functions including tumor promotion, tumor suppression, angiogenesis, and neutrophil activation. Abnormal overexp... |
|
TMPY-02929
|
ENTPD2 Protein, Human, Recombinant (aa 29-460, His)
ectonucleoside triphosphate diphosphohydrolase 2,NTPDase-2,R...
|
Human
|
Baculovirus Insect Cells
|
|
NTPDase 2, also known as ENTPD2, belongs to the ecto-nucleoside triphosphate diphosphohydrolase family (E-NTPDase). Members of E-NTPDase family are nucleotidases able to hydrolyze 5′-nucleoside tri- and/or diphosphates; the main role of these enzymes is the termination of purinergic signaling. NTPDases are ubiquitous and were previously shown in other parasites including the trypanosomatides of genus Leishmania and in T. brucei. NTPase activity would act as a timer and is crucial to T. gondii in... |
|
TMPY-02204
|
LBP Protein, Human, Recombinant (His)
BPIFD2,lipopolysaccharide binding protein
|
Human
|
HEK293 Cells
|
|
Lipopolysaccharide binding protein ( LBP ) is a glycoprotein that is synthesized principally by hepatocytes. LBP is a trace plasma protein that binds to the lipid A moiety of bacterial lipopolysaccharides ( LPSs ). LBP binds directly to the outer membrane of Gram-negative bacteria and purified aggregates of extracted endotoxin and catalyzes the delivery of endotoxin to the membrane ( mCD14, GPI-Linked ) and soluble ( sCD14 ) forms of CD14, thereby markedly increasing host cell sensitivity to end... |
|
TMPY-02904
|
TLR4 Protein, Human, Recombinant (His)
TLR-4,TOLL,toll-like receptor 4,ARMD10,TLR4,CD284
|
Human
|
Baculovirus Insect Cells
|
|
TLR4, also known as TLR-4, is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. TLR4 is most abundantly expressed... |
|
TMPY-04483
|
IRAK4 Protein, Human, Recombinant (His)
IPD1,NY-REN-64,REN64,interleukin-1 receptor-associated kinas...
|
Human
|
Baculovirus Insect Cells
|
|
Interleukin-1 receptor-associated kinase 4, also known as Renal carcinoma antigen NY-REN-64, IRAK-4, and IRAK4, is a member of the protein kinase superfamily, TKL Ser/Thr protein kinase family, and Pelle subfamily. IRAK4 contains one death domain and one protein kinase domain. IRAK4 is required for the efficient recruitment of IRAK1 to the IL-1 receptor complex following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization. ... |
|
TMPY-00105
|
Recombinant Protein G
|
|
E. coli
|
|
Protein G is a bacterial cell wall protein expressed at the cell surface of certain group C and group G Streptococcal strains.
It has affinity for both Fab- and Fc-fragments of human IgG by independent and separate binding sites. Binding to the Fc region of immunoglobulins from several species by a non-immune mechanism exhibits great affinity for almost all mammalian immunoglobulin G (IgG) classes, including all human IgG subclasses (IgG1, IgG2, IgG3 and IgG4) and also rabbit, mouse, and goat Ig... |
|
TMPH-03515
|
ClfA Protein, S. aureus (strain MSSA476), Recombinant
clfA,Clumping factor A,Fibrinogen-binding protein A,Fibrinog...
|
Staphylococcus aureus
|
E. coli
|
|
Cell surface-associated protein implicated in virulence. Promotes bacterial attachment exclusively to the gamma-chain of human fibrinogen. Induces formation of bacterial clumps. |
|
TMPH-03530
|
ClfA Protein, S. aureus (strain COL), Recombinant (E. coli, His)
clfA,Fibrinogen-binding protein A,Fibrinogen receptor A,Clum...
|
Staphylococcus aureus
|
E. coli
|
|
Cell surface-associated protein implicated in virulence. Promotes bacterial attachment exclusively to the gamma-chain of human fibrinogen. Induces formation of bacterial clumps. ClfA Protein, S. aureus (strain COL), Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 40.0 kDa and the accession number is Q5HHM8. |
|
TMPH-03531
|
ClfA Protein, S. aureus (strain COL), Recombinant (His)
Fibrinogen-binding protein A,clfA,Clumping factor A,Fibrinog...
|
Staphylococcus aureus
|
P. pastoris (Yeast)
|
|
Cell surface-associated protein implicated in virulence. Promotes bacterial attachment exclusively to the gamma-chain of human fibrinogen. Induces formation of bacterial clumps. ClfA Protein, S. aureus (strain COL), Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 38.0 kDa and the accession number is Q5HHM8. |
|
TMPH-03532
|
ClfB Protein, S. aureus (strain MRSA252), Recombinant (His & SUMO)
Clumping factor B,clfB,Fibrinogen receptor B,Fibrinogen-bind...
|
Staphylococcus aureus
|
E. coli
|
|
Cell surface-associated protein implicated in virulence by promoting bacterial attachment to both alpha- and beta-chains of human fibrinogen and inducing the formation of bacterial clumps. ClfB Protein, S. aureus (strain MRSA252), Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 69.8 kDa and the accession number is Q6GDH2. |
|
TMPH-03514
|
ClfA Protein, S. aureus (strain MSSA476), Recombinant (His & SUMO)
Fibrinogen receptor A,Fibrinogen-binding protein A,clfA,Clum...
|
Staphylococcus aureus
|
E. coli
|
|
Cell surface-associated protein implicated in virulence. Promotes bacterial attachment exclusively to the gamma-chain of human fibrinogen. Induces formation of bacterial clumps. ClfA Protein, S. aureus (strain MSSA476), Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 52.1 kDa and the accession number is Q6GB45. |
|
TMPH-03508
|
IpaH9.8 Protein, Shigella flexneri, Recombinant (His)
E3 ubiquitin-protein ligase ipaH9.8,ipaH9.8,Invasion plasmid...
|
Shigella flexneri
|
P. pastoris (Yeast)
|
|
Effector proteins function to alter host cell physiology and promote bacterial survival in host tissues. This protein is an E3 ubiquitin ligase that interferes with host's ubiquitination pathway and modulates the acute inflammatory responses, thus facilitating bacterial colonization within the host cell. IpaH9.8 Protein, Shigella flexneri, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 64.0 kDa and the accession number is D2AJU0. |
|
TMPH-00623
|
Flagellin Protein, E. coli, Recombinant (His & SUMO)
fliC,Flagellin
|
E. coli
|
E. coli
|
|
Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. |
|
TMPH-03720
|
YscM Protein, Yersinia enterocolitica, Recombinant (His & SUMO)
Yop proteins translocation protein M,yscM
|
Yersinia enterocolitica
|
E. coli
|
|
Belongs to an operon involved in the translocation of Yop proteins across the bacterial membranes or in the specific control of this function. |
|
TMPJ-00585
|
Complement C8 gamma Protein, Human, Recombinant (His)
C8 γ,Complement component C8 gamma chain,C8G,Complement comp...
|
Human
|
E. coli
|
|
Complement component C8 is a constituent of the membrane attack complex, C8 alpha, C8 beta and C8G. C8G is a secreted protein and comsists a disulfide-linked C8 alpha-gamma heterodimer and a non-covalently associated C8 beta chain. C8 alpha and C8 beta play an important role in complement-mediated bacterial killing together.C8 is involved in the formation of Membrane Attack Complex on bacterial cell membranes. C8 binds to the C5B-7 complex, forming the C5B-8 complex. C5-B8 binds C9 and acts as a... |
|
TMPK-01244
|
GDF-15 Protein, Mouse, Recombinant (hFc)
PTGFBPTGF-beta,PTGFB,PLAB,NAG-1,Placental TGF-β,RG-1,GDF15,G...
|
Mouse
|
HEK293 Cells
|
|
Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and that GDF15 was necessary for surviving both bacterial and viral infections, as well as sepsis. The protective effects of GDF15 were largely independent of pathogen control or the magnitude of inflammatory response, suggesting a role in disease tolerance. GDF-15 Protein, Mouse, Rec... |
|
TMPH-02879
|
REG3G Protein, Mouse, Recombinant (His)
Regenerating islet-derived protein III-gamma,Reg3g,Pancreati...
|
Mouse
|
P. pastoris (Yeast)
|
|
Bactericidal C-type lectin which acts exclusively against Gram-positive bacteria and mediates bacterial killing by binding to surface-exposed carbohydrate moieties of peptidoglycan. Restricts bacterial colonization of the intestinal epithelial surface and consequently limits activation of adaptive immune responses by the microbiota. The uncleaved form has bacteriostatic activity, whereas the cleaved form has bactericidal activity against L.monocytogenes and methicillin-resistant S.aureus. Regula... |
|
TMPK-00665
|
GDF-15 Protein, Cynomolgus, Recombinant (His)
PTGFBPTGF-beta,PTGFBPTGF-β,MIC-1,NAG-1,MIC1,PTGF-beta,PTGF-β...
|
Cynomolgus
|
E. coli
|
|
Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and that GDF15 was necessary for surviving both bacterial and viral infections, as well as sepsis. The protective effects of GDF15 were largely independent of pathogen control or the magnitude of inflammatory response, suggesting a role in disease tolerance. GDF-15 Protein, Cynomolgus... |
|
TMPK-00663
|
GDF-15 Protein, Cynomolgus, Recombinant (hFc)
PTGF-β,GDF-15,NAG-1,PTGF-beta,PDF,PTGFBPTGF-beta,GDF15,Place...
|
Cynomolgus
|
HEK293 Cells
|
|
Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and that GDF15 was necessary for surviving both bacterial and viral infections, as well as sepsis. The protective effects of GDF15 were largely independent of pathogen control or the magnitude of inflammatory response, suggesting a role in disease tolerance. GDF-15 Protein, Cynomolgus... |
|
TMPH-03726
|
YscM Protein, Yersinia pseudotuberculosis serotype I, Recombinant (His & SUMO)
Yop proteins translocation protein M,Low calcium response lo...
|
Yersinia pseudotuberculosis
|
E. coli
|
|
Belongs to an operon involved in the translocation of Yop proteins across the bacterial membranes or in the specific control of this function. |
|
TMPH-00328
|
Flagellin B(flaB) Protein, Campylobacter jejuni, Recombinant (His)
flaB,Flagellin B
|
Campylobacter jejuni
|
E. coli
|
|
Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. Flagellin B(flaB) Protein, Campylobacter jejuni, Recombinant (His) is expressed in E. coli expression system with C-6xHis tag. The predicted molecular weight is 61.6 kDa and the accession number is Q46114. |
|
TMPK-01245
|
GDF-15 Protein (Primary Amine Labeling), Mouse, Recombinant (hFc), Biotinylated
RG-1,GDF15,Placental TGF-beta,GDF-15,PTGFBPTGF-beta,NAG-1,PT...
|
Mouse
|
HEK293 Cells
|
|
Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and that GDF15 was necessary for surviving both bacterial and viral infections, as well as sepsis. The protective effects of GDF15 were largely independent of pathogen control or the magnitude of inflammatory response, suggesting a role in disease tolerance. GDF-15 Protein (Primary Am... |
|
TMPK-00197
|
GDF-15 Protein (Primary Amine Labeling), Human, Recombinant (H202D, hFc), Biotinylated
Placental TGF-β,GDF15,RG-1,MIC-1,PTGFB,PTGF-beta,PDF,PTGF-β,...
|
Human
|
HEK293 Cells
|
|
Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and that GDF15 was necessary for surviving both bacterial and viral infections, as well as sepsis. The protective effects of GDF15 were largely independent of pathogen control or the magnitude of inflammatory response, suggesting a role in disease tolerance. GDF-15 Protein (Primary Am... |
|
TMPH-00327
|
Flagellin A Protein, Campylobacter jejuni, Recombinant
flaA,Flagellin A
|
Campylobacter jejuni
|
E. coli
|
|
Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. Flagellin A Protein, Campylobacter jejuni, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 59.5 kDa and the accession number is Q46113. |
|
TMPH-00624
|
Flagellin Protein, E. coli, Recombinant
fliC,Flagellin
|
E. coli
|
E. coli
|
|
Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. Flagellin Protein, E. coli, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 51.2 kDa and the accession number is P04949. |
|
TMPY-01812
|
Enoyl-ACP Reductase Protein, E. coli, Recombinant (His)
b1288,JW1281,gts,ECK1283,qmeA,envM
|
E. coli
|
E. coli
|
|
Enoyl-ACP reductase, also known as NADH-dependent enoyl-ACP reductase and FABI, is a cell inner membrane and peripheral membrane protein which belongs to theshort-chain dehydrogenases/reductases (SDR) family and FabI subfamily. Microorganisms produce many kinds of antibiotics which function in an antagonistic capacity in nature where they have much competition. Bacterial FAS provides essential fatty acids for use in the assembly of key cellular components. Among them, FABI is an enoyl-ACP... |
|
TMPH-03574
|
SdrE Protein, S. aureus, Recombinant (His)
sdrE,Serine-aspartate repeat-containing protein E
|
Staphylococcus aureus
|
E. coli
|
|
Cell surface-associated calcium-binding protein which plays an important role in adhesion and pathogenesis. Contributes to the resistance to killing by innate immune components in blood and thus attenuates bacterial clearance by interacting with host complement factor H/CFAH and modulating its activity. Inhibits also bacterial opsonization and killing by interacting with host complement regulator C4BPA and thus inhibiting classical complement pathway activation. SdrE Protein, S. aureus, Recombin... |
|
TMPH-01058
|
Cathelicidin antimicrobial peptide Protein, Human, Recombinant (His & Myc & SUMO)
CAP18,Cathelicidin antimicrobial peptide,CAMP,FALL39,CAP-18,...
|
Human
|
E. coli
|
|
Binds to bacterial lipopolysaccharides (LPS), has antibacterial activity. Cathelicidin antimicrobial peptide Protein, Human, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Myc tag. The predicted molecular weight is 24.7 kDa and the accession number is P49913. |
|
TMPH-00326
|
Flagellin A Protein, Campylobacter jejuni, Recombinant (His)
Flagellin A,flaA
|
Campylobacter jejuni
|
E. coli
|
|
Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. Flagellin A Protein, Campylobacter jejuni, Recombinant (His) is expressed in E. coli expression system with C-6xHis tag. The predicted molecular weight is 61.5 kDa and the accession number is Q46113. |
|
TMPK-00664
|
GDF-15 Protein (Primary Amine Labeling), Cynomolgus, Recombinant (hFc), Biotinylated
Placental TGF-beta,PTGFBPTGF-β,PLAB,MIC-1,GDF15,NAG-1,RG-1,P...
|
Cynomolgus
|
HEK293 Cells
|
|
Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and that GDF15 was necessary for surviving both bacterial and viral infections, as well as sepsis. The protective effects of GDF15 were largely independent of pathogen control or the magnitude of inflammatory response, suggesting a role in disease tolerance. GDF-15 Protein (Primary Am... |
|
TMPK-00198
|
GDF-15 Protein (Primary Amine Labeling), Human, Recombinant (hFc), Biotinylated
MIC-1,PTGFBPTGF-β,GDF15,PTGF-β,GDF-15,PTGF-beta,Placental TG...
|
Human
|
HEK293 Cells
|
|
Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and that GDF15 was necessary for surviving both bacterial and viral infections, as well as sepsis. The protective effects of GDF15 were largely independent of pathogen control or the magnitude of inflammatory response, suggesting a role in disease tolerance. GDF-15 Protein (Primary Am... |
|
TMPH-01549
|
Interferon epsilon/IFNE Protein, Human, Recombinant (His)
IFNE,Interferon epsilon,Interferon epsilon-1
|
Human
|
E. coli
|
|
Type I interferon required for maintaining basal levels of IFN-regulated genes, including 2'-5'-oligoadenylate synthetase, IRF7 and ISG15, in the female reproductive tract. Directly mediates protection against viral and bacterial genital infections. |
|
TMPH-03504
|
Flagellin C Protein, Shigella flexneri, Recombinant (His)
fliC,Flagellin
|
Shigella flexneri
|
E. coli
|
|
Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. Flagellin C Protein, Shigella flexneri, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 62.1 kDa and the accession number is Q08860. |
|
TMPH-03011
|
EsxH Protein, Mycobacterium tuberculosis, Recombinant (His & SUMO)
Low molecular weight protein antigen 7,esxH,10 kDa antigen C...
|
Mycobacterium tuberculosis
|
E. coli
|
|
EsxH, in complex with EsxG, disrupts ESCRT function and impairs host phagosome maturation, thereby promoting intracellular bacterial growth. The complex acts by interacting, via EsxH, with the host hepatocyte growth factor-regulated tyrosine kinase substrate (HGS/HRS), a component of the ESCRT machinery. |
|
TMPH-03477
|
Phase 2 flagellin Protein, Salmonella typhimurium, Recombinant (Avi & His & MBP), Biotinylated
fljB,Phase 2 flagellin
|
Salmonella typhimurium
|
E. coli
|
|
Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. Phase 2 flagellin Protein, Salmonella typhimurium, Recombinant (Avi & His & MBP), Biotinylated is expressed in E. coli expression system with N-MBP and C-6xHis-Avi tag. The predicted molecular weight is 79.8 kDa and the accession number is P52616. |
|
TMPH-03100
|
PMAP-23 Protein, Pig, Recombinant (His & SUMO)
PMAP23,Antibacterial peptide PMAP-23,Myeloid anti
|
Sus scrofa (Pig)
|
E. coli
|
|
Exerts antimicrobial activity against both Gram-positive and negative bacteria at concentrations of 2-16 micro molar. Its activity appears to be mediated by its ability to damage bacterial membranes. PMAP-23 Protein, Pig, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 19.0 kDa and the accession number is P49930. |
|
TMPH-03704
|
Cytolysin Protein, Vibrio vulnificus, Recombinant (His & Myc)
Cytolysin,vvhA
|
Vibrio vulnificus
|
E. coli
|
|
Bacterial hemolysins are exotoxins that attack blood cell membranes and cause cell rupture by mechanisms not clearly defined. Cytolysin Protein, Vibrio vulnificus, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 55.8 kDa and the accession number is P19247. |
|
TMPH-03266
|
CHI3L1 Protein, Rat, Recombinant (His)
Chi3l1,Cartilage glycoprotein 39,CGP-39,GP-39,Chitinase-3-li...
|
Rat
|
E. coli
|
|
Carbohydrate-binding lectin with a preference for chitin. Has no chitinase activity. May play a role in tissue remodeling and in the capacity of cells to respond to and cope with changes in their environment. Plays a role in T-helper cell type 2 (Th2) inflammatory response and IL-13-induced inflammation, regulating allergen sensitization, inflammatory cell apoptosis, dendritic cell accumulation and M2 macrophage differentiation. Facilitates invasion of pathogenic enteric bacteria into colonic mu... |
|
TMPJ-00057
|
REG3G Protein, Human, Recombinant (hFc)
PAP-1B,REG3G,Regenerating islet-derived protein III-γ,Regene...
|
Human
|
HEK293 Cells
|
|
Pancreatitis-associated protein IB, Regenerating islet-derived protein III-gamma, is a secreted protein which contains 1 C-type lectin domain. It is expressed almost exclusively in the pancreas and also expressed in testis, but not found in small intestine. This protein might be a stress protein involved in the control of bacterial proliferation. |
|
TMPH-02875
|
ROMO1 Protein, Mouse, Recombinant (His)
Protein MGR2 homolog,Romo1,Reactive oxygen species modulator...
|
Mouse
|
E. coli
|
|
Has antibacterial activity against a variety of bacteria including S.aureus, P.aeruginosa and M.tuberculosis. Acts by inducing bacterial membrane breakage.; Induces production of reactive oxygen species (ROS) which are necessary for cell proliferation. May play a role in inducing oxidative DNA damage and replicative senescence. May play a role in the coordination of mitochondrial morphology and cell proliferation. |
|
TMPH-00507
|
PGRP-SC2 Protein, Drosophila melanogaster, Recombinant (His & Myc)
PGRP-SC2,Peptidoglycan-recognition protein SC2
|
Fruit fly
|
E. coli
|
|
N-acetylmuramyl-L-alanine amidase involved in innate immunity by degrading bacterial peptidoglycans (PGN). Probably plays a scavenger role by digesting biologically active PGN into biologically inactive fragments. Has no direct bacteriolytic activity. PGRP-SC2 Protein, Drosophila melanogaster, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 25.2 kDa and the accession number is Q9V4X2. |
|
TMPH-02019
|
REG3A Protein, Human, Recombinant (GST)
Regenerating islet-derived protein 3-alpha,REG3A,Regeneratin...
|
Human
|
E. coli
|
|
Bactericidal C-type lectin which acts exclusively against Gram-positive bacteria and mediates bacterial killing by binding to surface-exposed carbohydrate moieties of peptidoglycan. Regulates keratinocyte proliferation and differentiation after skin injury via activation of EXTL3-PI3K-AKT signaling pathway. REG3A Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 43.6 kDa and the accession number is Q06141. |
|
TMPH-02989
|
ESAT-6 Protein, Mycobacterium bovis, Recombinant (His & Myc)
ESAT-6,6 kDa early secretory antigenic target,esxA
|
Mycobacterium bovis
|
E. coli
|
|
A secreted protein. Acts as a strong host T-cell antigen. Plays a number of roles in modulating the host's immune response to infection as well as being responsible for bacterial escape into the host cytoplasm. ESAT-6 Protein, Mycobacterium bovis, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 17.2 kDa and the accession number is P0A565. |
|
TMPK-00144
|
CEACAM3 Protein, Human, Recombinant (hFc)
CEACAM3,CGM1,CEA,CD66d
|
Human
|
HEK293 Cells
|
|
The human granulocyte-specific receptor carcinoembryonic antigen-related cell adhesion molecule (CEACAM)3 is critically involved in the opsonin-independent recognition of several bacterial pathogens. CEACAM3-mediated phagocytosis depends on the integrity of an ITAM-like sequence within the cytoplasmic domain of CEACAM3 and is characterized by rapid stimulation of the GTPase Rac. |
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TMPH-00672
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Metalloprotease stcE Protein, E. coli O157:H7, Recombinant (His)
stcE,Neutral zinc metalloprotease StcE,Metalloprotease StcE,...
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E. coli
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E. coli
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Virulence factor that contributes to intimate adherence of enterohemorrhagic E.coli (EHEC) O157:H7 to host cells. Is able to cleave the secreted human mucin 7 (MUC7) and the glycoprotein 340 (DMBT1/GP340). Also cleaves human C1 inhibitor (SERPING1), a regulator of multiple inflammatory pathways, and binds and localizes it to bacterial and host cell surfaces, protecting them from complement-mediated lysis. Therefore, the current model proposes two roles for StcE during infection: it acts first as... |
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