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Lenampicillin hydrochloride

产品编号 T15734Cas号 80734-02-7
别名 盐酸仑氨苄西林, KBT 1585 hydrochloride

Lenampicillin hydrochloride is an orally active prodrug of Ampicillin. Lenampicillin hydrochloride is an effective beta-lactam antibacterial agent that inhibits bacterial penicillin-binding proteins. It is applied in the investigation of suppurative skin and soft tissue infection.

Lenampicillin hydrochloride

Lenampicillin hydrochloride

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产品编号 T15734 别名 盐酸仑氨苄西林, KBT 1585 hydrochlorideCas号 80734-02-7

Lenampicillin hydrochloride is an orally active prodrug of Ampicillin. Lenampicillin hydrochloride is an effective beta-lactam antibacterial agent that inhibits bacterial penicillin-binding proteins. It is applied in the investigation of suppurative skin and soft tissue infection.

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产品介绍

生物活性
产品描述
Lenampicillin hydrochloride is an orally active prodrug of Ampicillin. Lenampicillin hydrochloride is an effective beta-lactam antibacterial agent that inhibits bacterial penicillin-binding proteins. It is applied in the investigation of suppurative skin and soft tissue infection.
体内活性
Lenampicillin hydrochloride (LAPC) is identified for its main metabolites in rats and dogs. The main metabolite in peripheral plasma is 2,3-butanediol in rats and dogs, On the other hand, high levels of acetoin are found in portal plasma for an early period after the dosing of LAPC. These results show that the biotransformation of propriety in LAPC to acetoin carried out mainly in intestinal tissues, but acetoin is converted to 2,3-butanediol in the liver[3]. Lenampicillin hydrochloride (p.o.; 0-1000 mg/kg) does not cause death in dogs, and the maximum dose of in this acute toxicity study is recorded because of causing emesis[2].
别名盐酸仑氨苄西林, KBT 1585 hydrochloride
化学信息
分子量497.95
分子式C21H24ClN3O7S
CAS No.80734-02-7
储存&溶解度
存储Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

计算器

  • 摩尔浓度 计算器
  • 稀释 计算器
  • 配液 计算器
  • 分子量 计算器

体内实验配液计算器

请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法:
TargetMol | Animal experiments比如您的给药剂量是 10 mg/kg ,每只动物体重 20 g ,给药体积 100 μLTargetMol | Animal experiments 一共给药动物 10 只 ,您使用的配方为 5% TargetMol | reagent DMSO+ 30%PEG300+ 5%Tween 80 + 60% ddH2O. 那么您的工作液浓度为 2 mg/mL
母液配置方法: 2 mg 药物溶于 50 μLDMSOTargetMol | reagent ( 母液浓度为 40 mg/mL ), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:50μLDMSOTargetMol | reagent 母液,添加 300 μLPEG300TargetMol | reagent 混匀澄清,再加 50μLTween 80, 混匀澄清,再加 600μLddH2OTargetMol | reagent 混匀澄清

以上为“体内实验配液计算器”的使用方法举例,并不是具体某个化合物的推荐配制方式,请根据您的实验动物和给药方式选择适当的溶解方案。

1 请输入动物实验的基本信息
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2 请输入动物体内配方组成,不同的产品配方组成不同,如有配方需求,可先联系我们提供正确的体内配方。
% DMSO
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%Tween 80
%ddH2O

剂量转换

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