SPR206

Name: SPR206
Brand: TargetMol
SKU: T12991
Price: 265 USD
Availability: InStock
Rating: 4.5 (1 reviews)

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产品编号 T12991

SPR206 is a polymyxin analogue and an important class of antibiotic for the treatment of bacterial infections due to multidrug resistant Gram-negative pathogen.

SPR206

还可以

产品编号 T12991

SPR206 is a polymyxin analogue and an important class of antibiotic for the treatment of bacterial infections due to multidrug resistant Gram-negative pathogen.

规格	价格	库存	数量
100 mg	询价	期货
500 mg	询价	期货

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产品介绍

生物活性

产品描述	SPR206 is a polymyxin analogue and an important class of antibiotic for the treatment of bacterial infections due to multidrug resistant Gram-negative pathogen.
靶点活性	Pseudomonas aeruginosa Pa14:（MIC）0.125 mg/L , Acinetobacter baumannii (NCTC13301):0.125 mg/L
体外活性	SPR206 has strong anti-microbial properties against Gram-negative bacteria. The MIC values of SPR206 against E. coli IHMA558090, E. coli ATCC 25922, K. pneumonia ATCC 13882, P. aeruginosa ATCC 27853, A. baumannii NCTC13424 and A. baumannii ATCC 19003 are 8 mg/L, 0.125 mg/L, 0.125 mg/L, 0.25 mg/L, 0.06 mg/L and 0.125 mg/L, respectively, together with lower cytotoxicity [1].
体内活性	In lung tissue and in the thigh model,SPR206 (0.125-30 mg/kg; intravenous injection or subcutaneous injection; every 8 hours or every 4 hours; for 16 hours or 24 hours; neutropenic mice) treatment reduces the burden of Pa14 and NCTC13301 [2].