|
TMPY-02483
|
ATP citrate lyase/ACLY Protein, Human, Recombinant (His)
ATPCL,ACL,ATP citrate lyase,CLATP
|
Human
|
Baculovirus Insect Cells
|
|
ATP citrate lyase, also known as Acly or Acl, is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is composed of two polymer chains which are polypeptides in human. ATP citrate lyase is responsible for catalyzing the conversion of citrate and CoA into acetyl-CoA and oxaloacetate, along with the hydrolysis of ATP. A definitive role for ATP citrate lyase in tumorigenesis has emerged from ATP citrate lyase RNAi and chemical inhibitor studies, show... |
|
TMPY-04070
|
Citrate Synthase Protein, Human, Recombinant (His)
citrate synthase
|
Human
|
Baculovirus Insect Cells
|
|
Chondroitin sulphate (CS) glycosaminoglycan chains on cell and extracellular matrix proteoglycans (PGs) can no longer be regarded as merely hydrodynamic space fillers. Overwhelming evidence over recent years indicates that sulphation motif sequences within the CS chain structure are a source of significant biological information to cells and their surrounding environment. CS sulphation motifs have been shown to interact with a wide variety of bioactive molecules, e.g. cytokines, growth factors, ... |
|
TMPH-03096
|
Profilin 2 Protein, Phleum pratense, Recombinant (His & Myc)
Pollen allergen Phl p 12,Allergen Phl p 11,Profilin 4,PRO4,P...
|
Phleum pratense
|
E. coli
|
|
Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. Profilin 2 Protein, Phleum pratense, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 21.5 kDa and the accession number is O24650. |
|
TMPY-02003
|
FH/Fumarate Hydratase Protein, Human, Recombinant (His)
fumarate hydratase,MCL,LRCC,MCUL1,FMRD,HLRCC
|
Human
|
E. coli
|
|
Fumarate Hydratase (FH) is an enzymatic component of the tricarboxylic acid (TCA) cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate. It exists in both a cytosolic form and an N-terminal extended form, differing only in the translation start site used. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension generates the same form as in the cytoplasm. Fumarate Hydratase is similar to some thermostable class II fumarases and func... |
|
TMPY-06149
|
Phl p 5 Protein, Phleum pratense, Recombinant (His)
|
Phleum pratense
|
HEK293 Cells
|
|
Phl p 5 Protein, Phleum pratense, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 30.9 kDa and the accession number is Q40960-1. |
|
TMPY-02413
|
Isocitrate dehydrogenase/IDH1 Protein, Human, Recombinant (His)
HEL-S-26,HEL-216,IDP,IDCD,PICD,IDH,isocitrate dehyd...
|
Human
|
E. coli
|
|
Isocitrate dehydrogenase/IDH1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 48 kDa and the accession number is O75874. |
|
TMPH-00132
|
Vertebrate ancient opsin Protein, Atlantic salmon, Recombinant (B2M & His)
Vertebrate ancient opsin
|
Salmo salar
|
E. coli
|
|
N/A. Vertebrate ancient opsin Protein, Atlantic salmon, Recombinant (B2M & His) is expressed in E. coli expression system with N-6xHis-B2M tag. The predicted molecular weight is 22.5 kDa and the accession number is O13018. |
|
TMPY-06015
|
Phl p 2 Protein, Phleum pratense, Recombinant (His)
|
Phleum pratense
|
HEK293 Cells
|
|
Phl p 2 Protein, Phleum pratense, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 13.1 kDa and the accession number is P43214-1. |
|
TMPY-06016
|
Phl p 5 Protein, Phleum pratense, Recombinant
|
Phleum pratense
|
E. coli
|
|
Phl p 5 Protein, Phleum pratense, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 28.7 kDa and the accession number is Q40960-1. |
|
TMPH-03095
|
Phl p 6 Protein, Phleum pratense, Recombinant (His & Myc)
Pollen allergen Phl p 6,Allergen Phl p VI,PHLPVI
|
Phleum pratense
|
E. coli
|
|
Phl p 6 Protein, Phleum pratense, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 19.2 kDa and the accession number is P43215. |
|
TMPH-03093
|
Phl p 5a Protein, Phleum pratense, Recombinant (His & SUMO)
Allergen Phl p Va,Pollen allergen Phl p 5a
|
Phleum pratense
|
E. coli
|
|
N/A. Phl p 5a Protein, Phleum pratense, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 44.5 kDa and the accession number is Q40962. |
|
TMPH-03412
|
Citrate synthase Protein, Rickettsia australis, Recombinant (His & Myc)
gltA,Citrate synthase
|
Rickettsia australis
|
E. coli
|
|
Citrate synthase Protein, Rickettsia australis, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 53.6 kDa and the accession number is P51039. |
|
TMPH-03094
|
Phl p 5b Protein, Phleum pratense, Recombinant (His & SUMO)
Pollen allergen Phl p 5b,Allergen Phl p Vb
|
Phleum pratense
|
E. coli
|
|
Has ribonuclease activity. May be involved in host-pathogen interactions. Phl p 5b Protein, Phleum pratense, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 42.1 kDa and the accession number is Q40963. |
|
TMPH-00007
|
HMGCR Protein, Human, Recombinant (His)
HMGCR,3-hydroxy-3-methylglutaryl-coenzyme A reductase
|
Human
|
E. coli
|
|
Catalyzes the conversion of (3S)-hydroxy-3-methylglutaryl-CoA (HMG-CoA) to mevalonic acid, the rate-limiting step in the synthesis of cholesterol and other isoprenoids, thus plays a critical role in cellular cholesterol homeostasis. HMGCR is the main target of statins, a class of cholesterol-lowering drugs. |
|
TMPY-02956
|
Apolipoprotein L/APOL1 Protein, Human, Recombinant (His)
APOL1,apolipoprotein L1,APOL,FSGS4,APOL-I,APO-L
|
Human
|
Baculovirus Insect Cells
|
|
APOL1, also known as apolipoprotein L1, is a minor apoprotein component of HDL (High-density lipoprotein) or 'good cholesterol' which is synthesized in the liver and also in many other tissues, including pancreas, kidney, and brain. APOL1 belongs to the apolipoprotein L family. It may play a role in lipid exchange and transport throughout the body. It may also participate in reverse cholesterol transport from peripheral cells to the liver. Defects in APOL1 are the cause of focal segmental glomer... |
|
TMPY-02801
|
PHGDH Protein, Human, Recombinant (His)
phosphoglycerate dehydrogenase,HEL-S-113,3PGDH,NLS1...
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Human
|
E. coli
|
|
PHGDH is a member of the D-isomer specific 2-hydroxyacid dehydrogenase family. This new family consists of D-isomer-stereospecific enzymes. The conserved residues in this family appear to be the residues involved in the substrate binding and the catalytic reaction, and thus to be targets for site-directed mutagenesis. A number of NAD-dependent 2-hydroxyacid dehydrogenases which seem to be specific for the D-isomer of their substrate have been shown to be functionally and structurally related. PH... |
|
TMPY-02481
|
ACOX1 Protein, Human, Recombinant (His)
PALMCOX,ACOX,SCOX,acyl-CoA oxidase 1, palmitoyl
|
Human
|
Baculovirus Insect Cells
|
|
Peroxisomal acyl-coenzyme A oxidase 1(ACOX1 or AOX) is the first enzyme of the fatty acid beta-oxidation pathway and belongs to the Acyl-CoA oxidase family. Human liver peroxisomes contain two acyl-CoA oxidases, namely, palmitoyl-CoA oxidase (ACOX1/AOX) and a branched chain acyl-CoA oxidase. The palmitoyl-CoA oxidase (ACOX1/AOX) oxidizes the CoA esters of straight chain fatty acids and prostaglandins and donates electrons directly to molecular oxygen, thereby producing H2O2. Human ACOX1/AOX is a... |
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TMPY-02185
|
Coagulation factor XIII B/F13B Protein, Human, Recombinant (His)
Coagulation factor 13,coagulation factor XIII, B polypeptide...
|
Human
|
HEK293 Cells
|
|
Coagulation factor XIII B chain, also known as Fibrin-stabilizing factor B subunit, Protein-glutamine gamma-glutamyltransferase B chain, Transglutaminase B chain and F13B, is a secreted protein which contains 1 Sushi ( CCP / SCR ) domains. Coagulation factor XIII is the last zymogen to become activated in the blood coagulation cascade. Plasma factor XIII is a heterotetramer composed of 2 A subunits and 2 B subunits. The A subunits have catalytic function, and the B subunits do not have en... |
|
TMPH-00264
|
Decorin Protein, Bovine, Recombinant (His)
Decorin,Bone proteoglycan II,DCN,PG-S2
|
Bovine
|
E. coli
|
|
May affect the rate of fibrils formation. Decorin Protein, Bovine, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 40.5 kDa and the accession number is P21793. |
|
TMPJ-00839
|
ODC1 Protein, Human, Recombinant (His)
ODC1,Ornithine decarboxylase
|
Human
|
E. coli
|
|
Ornithine decarboxylase (ODC1) is an enzyme which belongs to the Orn/Lys/Arg decarboxylase class-II family. ODC1 is the rate-limiting enzyme of the polyamine biosynthesis pathway which catalyzes ornithine to putrescine. The activity level for the enzyme varies in response to growth-promoting stimuli and exhibits a high turnover rate in comparison to other mammalian proteins. |
|
TMPH-00679
|
Peptide deformylase Protein, E. coli O157:H7, Recombinant (His)
Polypeptide deformylase,Peptide deformylase,def
|
E. coli
|
P. pastoris (Yeast)
|
|
Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. |
|
TMPH-02958
|
Tryptophan Hydroxylase 1 Protein, Mouse, Recombinant (His & SUMO)
Tryptophan 5-monooxygenase 1,Tryptophan 5-hydroxylase 1,Tph1
|
Mouse
|
E. coli
|
|
Oxidizes L-tryptophan to 5-hydroxy-l-tryptophan in the rate-determining step of serotonin biosynthesis. Tryptophan Hydroxylase 1 Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 67.3 kDa and the accession number is P17532. |
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TMPH-01404
|
PYGL Protein, Human, Recombinant (GST)
Glycogen phosphorylase, liver form,PYGL
|
Human
|
E. coli
|
|
Allosteric enzyme that catalyzes the rate-limiting step in glycogen catabolism, the phosphorolytic cleavage of glycogen to produce glucose-1-phosphate, and plays a central role in maintaining cellular and organismal glucose homeostasis. PYGL Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 123.9 kDa and the accession number is P06737. |
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TMPH-02476
|
HMGCR Protein, Mouse, Recombinant (His)
Hmgcr,3-hydroxy-3-methylglutaryl-coenzyme A reductase
|
Mouse
|
E. coli
|
|
Catalyzes the conversion of (3S)-hydroxy-3-methylglutaryl-CoA (HMG-CoA) to mevalonic acid, the rate-limiting step in the synthesis of cholesterol and other isoprenoids, thus plays a critical role in cellular cholesterol homeostasis. HMGCR Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 20.4 kDa and the accession number is Q01237. |
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TMPY-01959
|
Tryptophan Hydroxylase 1/TPH-1 Protein, Human, Recombinant (His)
TPRH,tryptophan hydroxylase 1,TRPH
|
Human
|
E. coli
|
|
Tryptophan 5-hydroxylase 1, also known as Tryptophan 5-monooxygenase 1, Tryptophan hydroxylase 1, TPH1, TPH and TPRH, is an enzyme that belongs to the biopterin-dependent aromatic amino acid hydroxylase family. TPH1 contains one ACT domain. Tryptophan hydroxylase catalyzes the biopterin-dependent monooxygenation of tryptophan to 5-hydroxytryptophan (5HT), which is subsequently decarboxylated to form the neurotransmitter serotonin. It is the rate-limiting enzyme in the biosynthesis of serotonin. ... |
|
TMPY-04767
|
PMVK Protein, Human, Recombinant (His)
PMK,PMKA,phosphomevalonate kinase,HUMPMKI,PMKASE
|
Human
|
E. coli
|
|
PMVK is a peroxisomal enzyme that catalyzes the conversion of mevalonate 5-phosphate into mevalonate 5-diphosphate, the fifth reaction of the cholesterol biosynthetic pathway. Studies in rat show that the message level and the enzyme activity of PMVK is regulated by sterol, and that this regulation is coordinated with 3-hydroxy-3-methylglutaryl coenzyme A reductase, the rate-limiting enzyme of cholesterol biosynthesis. |
|
TMPK-00436
|
SARS-COV-2 Spike S1 Protein (D614G, His & Avi)
Spike,S1 protein,Spike protein S1,S glycoprotein Subunit1,S1...
|
SARS-CoV-2
|
HEK293 Cells
|
|
The SARS-CoV-2 spike (S) protein is the target of vaccine design efforts to end the COVID-19 pandemic. Despite a low mutation rate, isolates with the D614G substitution in the S protein appeared early during the pandemic, and are now the dominant form worldwide. Here, we analyze the D614G mutation in the context of a soluble S ectodomain construct. |
|
TMPH-03375
|
Stathmin-2 Protein, Rat, Recombinant (His)
Superior cervical ganglion-10 protein,Stmn2,Stathmin-2
|
Rat
|
E. coli
|
|
Regulator of microtubule stability. When phosphorylated by MAPK8, stabilizes microtubules and consequently controls neurite length in cortical neurons. In the developing brain, negatively regulates the rate of exit from multipolar stage and retards radial migration from the ventricular zone. Stathmin-2 Protein, Rat, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 26.7 kDa and the accession number is P21818. |
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TMPH-03567
|
Peptide deformylase Protein, S. aureus, Recombinant (His & SUMO)
Peptide deformylase,def,Polypeptide deformylase
|
Staphylococcus aureus
|
E. coli
|
|
Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. Peptide deformylase Protein, S. aureus, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 36.6 kDa and the accession number is P68826. |
|
TMPH-00678
|
Peptide deformylase Protein, E. coli O157:H7, Recombinant (His & SUMO)
Peptide deformylase,def,Polypeptide deformylase
|
E. coli
|
E. coli
|
|
Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. Peptide deformylase Protein, E. coli O157:H7, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 35.2 kDa and the accession number is P0A6K5. |
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TMPH-02269
|
Tyrosinase/TYR Protein, Human, Recombinant (His)
Tyrosinase,SK29-AB,Monophenol monooxygenase,Tumor rejection ...
|
Human
|
P. pastoris (Yeast)
|
|
This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. Catalyzes the initial and rate limiting step in the cascade of reactions leading to melanin production from tyrosine. In addition to hydroxylating tyrosine to DOPA (3,4-dihydroxyphenylalanine), also catalyzes the oxidation of DOPA to DOPA-quinone, and possibly the oxidation of DHI (5,6-dihydroxyindole) to indole-5,6 quinone. |
|
TMPH-03566
|
Peptide deformylase Protein, S. aureus, Recombinant (His)
Polypeptide deformylase,def,Peptide deformylase
|
Staphylococcus aureus
|
P. pastoris (Yeast)
|
|
Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. Peptide deformylase Protein, S. aureus, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 22.6 kDa and the accession number is P68826. |
|
TMPH-00702
|
Peptide deformylase Protein, E. coli, Recombinant (His & SUMO)
Polypeptide deformylase,def,Peptide deformylase
|
E. coli
|
E. coli
|
|
Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. Peptide deformylase Protein, E. coli, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 35.2 kDa and the accession number is P0A6K3. |
|
TMPH-02642
|
ECHS1 Protein, Mouse, Recombinant (C225S, HA & His)
mECH,Enoyl-CoA hydratase, mitochondrial,SCEH,mECH1,ECHS1
|
Mouse
|
Baculovirus Insect Cells
|
|
Straight-chain enoyl-CoA thioesters from C4 up to at least C16 are processed, although with decreasing catalytic rate. Has high substrate specificity for crotonyl-CoA and moderate specificity for acryloyl-CoA, 3-methylcrotonyl-CoA and methacrylyl-CoA. It is noteworthy that binds tiglyl-CoA, but hydrates only a small amount of this substrate. ECHS1 Protein, Mouse, Recombinant (C225S, HA & His) is expressed in Baculovirus insect cells with N-10xHis, C-HA tag. The predicted molecular weight is 32.0... |
|
TMPH-02270
|
Tyrosinase/TYR Protein, Human, Recombinant (His & SUMO)
SK29-AB,LB24-AB,TYR,Monophenol monooxygenase,Tyrosinase,Tumo...
|
Human
|
E. coli
|
|
This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. Catalyzes the initial and rate limiting step in the cascade of reactions leading to melanin production from tyrosine. In addition to hydroxylating tyrosine to DOPA (3,4-dihydroxyphenylalanine), also catalyzes the oxidation of DOPA to DOPA-quinone, and possibly the oxidation of DHI (5,6-dihydroxyindole) to indole-5,6 quinone. |
|
TMPH-03568
|
Phospholipase C Protein, S. aureus, Recombinant (His)
hlb,Beta-hemolysin,Phospholipase C,Beta-toxin,Sphingomyelina...
|
Staphylococcus aureus
|
P. pastoris (Yeast)
|
|
Bacterial hemolysins are exotoxins that attack blood cell membranes and cause cell rupture. Beta-hemolysin is a phospholipase C with specific activity toward sphingomyelins. Has a high specificity for sphingomyelin, hydrolyzes lysophosphatidylcholine at a much lower rate, but has no activity towards phosphatidylcholine, phosphatidylethanolamine, or phosphatidylserine. Phospholipase C Protein, S. aureus, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 3... |
|
TMPY-04474
|
PFKFB3 Protein, Human, Recombinant (His & GST)
IPFK2,6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3,...
|
Human
|
Baculovirus Insect Cells
|
|
Fructose-2,6-biphosphatase 3, also known as 6-phosphofructo-2-kinase or PFK2 or PFKFB3, is a potent activator of phosphofructokinase, which is a rate-limiting enzyme of glycolysis. Highly phosphorylated PFKFB3 protein was found in human tumor cells, vascular endothelial cells, and smooth muscle cells. Fructose 2,6-bisphosphate (Fru-2,6-BP) is an allosteric activator of 6-phosphofructo-1-kinase (PFK-1), a rate-limiting enzyme and essential control point in glycolysis. The concentration of PFK2 de... |
|
TMPJ-00989
|
MTHFS Protein, Human, Recombinant (His)
5-formyltetrahydrofolate cyclo-ligase,10-methenyl-tetrahydro...
|
Human
|
E. coli
|
|
5-formyltetrahydrofolate cyclo-ligase (MTHFS) belongs to the 5-formyltetrahydrofolate cyclo-ligase family. It is an enzyme that catalyzes the conversion of 5-formyltetrahydrofolate to 5,10-methenyltetrahydrofolate, contributes to tetrahydrofolate metabolism. MTHFS helps regulate carbon flow through the folate-dependent one-carbon metabolic network that supplies carbon for the biosynthesis of purines, thymidine and amino acids. An increased activity of the encoded protein can result in an increas... |
|
TMPH-00524
|
ATP-dependent DNA helicase dda Protein, Enterobacteria phage T4, Recombinant (His)
ATP-dependent DNA helicase dda,dda,sud
|
Enterobacteria phage T4
|
E. coli
|
|
DNA helicase that stimulates viral DNA replication and recombination. Plays a role in T4 DNA replication initiation by selecting and activating DNA origins. Acts by dissociating and reassociating with the DNA molecule being unwound. Unwinds DNA as a monomer in a 5'-to-3' direction at a rate of 250 bp/s and can efficiently displace proteins from the DNA. ATP-dependent DNA helicase dda Protein, Enterobacteria phage T4, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. T... |
|
TMPY-04152
|
RAB7A Protein, Rat, Recombinant (His)
RAB7A, member RAS oncogene family,Rab7
|
Rat
|
E. coli
|
|
RAB7A is a ubiquitous small GTPase, which controls transport to late endocytic compartments. Silencing or overexpression of wild type RAB7A changed the soluble/insoluble rate of peripherin indicating that RAB7A is important for peripherin organization and function. Besides, disease-causing RAB7A mutant proteins bind more strongly to peripherin and their expression causes a significant increase in the amount of soluble peripherin. The altered interaction between disease-causing RAB7A mutants and ... |
|
TMPJ-01368
|
GPC1 Protein, Mouse, Recombinant (His)
Gpc1,Glypican-1
|
Mouse
|
HEK293 Cells
|
|
Glypican-1 is a cell membrane protein and belongs to the glypican family. The protein may act as a catalyst in increasing the rate of conversion of prion protein PRPN(C) to PRNP(Sc) via associating (via the heparan sulfate side chains) with both forms of PRPN, targeting them to lipid rafts and facilitating their interaction. It is required for proper skeletal muscle differentiation by sequestering FGF2 in lipid rafts preventing its binding to receptors (FGFRs) and inhibiting the FGF-mediated sig... |
|
TMPH-03759
|
ECHS1 Protein, Mouse, Recombinant (HA & His)
Enoyl-CoA hydratase, mitochondrial,ECHS1,mECH,mECH1,SCEH
|
Mouse
|
E. coli
|
|
Straight-chain enoyl-CoA thioesters from C4 up to at least C16 are processed, although with decreasing catalytic rate. Has high substrate specificity for crotonyl-CoA and moderate specificity for acryloyl-CoA, 3-methylcrotonyl-CoA and methacrylyl-CoA. It is noteworthy that binds tiglyl-CoA, but hydrates only a small amount of this substrate. ECHS1 Protein, Mouse, Recombinant (HA & His) is expressed in E. coli expression system with N-10xHis, C-HA tag. The predicted molecular weight is 35.6 kDa a... |
|
TMPY-02890
|
ERP27 Protein, Human, Recombinant (mFc)
endoplasmic reticulum protein 27,C12orf46,PDIA8
|
Human
|
HEK293 Cells
|
|
ERP27 contains 1 thioredoxin domain and is a noncatalytic member of the protein disulfide isomerase family. Protein disulfide isomerases (PDIs) constitute a family of structurally related enzymes which catalyze disulfide bonds formation, reduction, or isomerization of newly synthesized proteins in the lumen of the endoplasmic reticulum (ER). They act also as chaperones, and are, therefore, part of a quality-control system for the correct folding of the proteins in the same subcellular compartmen... |
|
TMPY-03603
|
AHSP Protein, Human, Recombinant
ERAF,alpha hemoglobin stabilizing protein,α hemoglobin stabi...
|
Human
|
E. coli
|
|
AHSP, also known as ERAF, is a conserved mammalian erythroid protein which belongs to the AHSP family. It is expressed in blood and bone marrow. AHSP facilitates the production of Hemoglobin A by stabilizing free α-globin. It rapidly binds to ferrous α with association (k'(AHSP)) and dissociation (k(AHSP)) rate constants of ≈1 μm(-1) s(-1) and .2 s(-1), respectively, at pH 7.4 at 22 ℃. A small slow phase was observed when AHSP binds to excess ferrous αCO. This slow phase appears to be due to cis... |
|
TMPJ-00149
|
Complement Factor D/CFD Protein, Mouse, Recombinant (His)
C3 convertase activator,28 kDa adipocyte protein,Cfd,Adipsin...
|
Mouse
|
HEK293 Cells
|
|
Complement factor D, also known as adipsin, is a member of the chymotrypsin family of serine proteases, which plays an essential role in host defense as the rate-limiting enzyme in the alternative pathway of complement activation. Complement factor D activates a convertase (C3bBb) responsible for cleavage of the complement protein C3, which leads to the activation of terminal complement component C5-9 to form the membrane attack complex on microbial or cellular surfaces. It also functions in the... |
|
TMPH-02675
|
GCGR Protein, Mouse, Recombinant (GST)
Glucagon receptor,Gcgr
|
Mouse
|
E. coli
|
|
G-protein coupled receptor for glucagon that plays a central role in the regulation of blood glucose levels and glucose homeostasis. Regulates the rate of hepatic glucose production by promoting glycogen hydrolysis and gluconeogenesis. Plays an important role in mediating the responses to fasting. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. ... |
|
TMPJ-00787
|
GUSB Protein, E. coli, Recombinant (His)
uidA,β-glucuronidase,Beta-glucuronidase,GUS
|
E. coli
|
E. coli
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Beta-D-glucuronidase from E.coli is a highly specific enzyme in hydrolyzing glucuronides. Beta-D-glucuronidase (GLUase) activity can be measured as the rate of production of fluorescent methylumbelliferone (MU), resulting from the hydrolysis of the substrate 4-methylumbelliferyl-β-d-glucuronide (MUGLU), which is an effective and rapid method for detection and verification of E. coli in food, water, and environmental samples. High purity recombinant beta-Glucuronidase is used in research, bioche... |
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TMPH-03524
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KAS III Protein, S. aureus, Recombinant (His & Myc)
3-oxoacyl-[acyl-carrier-protein] synthase 3,3-oxoacyl-[acyl-...
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Staphylococcus aureus
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E. coli
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Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids. KAS III Protein, S. au... |
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TMPY-04771
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CARKL Protein, Human, Recombinant (His & GST)
SHK,CARKL,sedoheptulokinase
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Human
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Baculovirus Insect Cells
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CARKL, also known as SHPK, is a nonprotein kinase of glucose metabolism. CARKL has weak homology to several carbohydrate kinases, a class of proteins involved in the phosphorylation of sugars as they enter a cell, inhibiting return across the cell membrane. CARKL catalyzes an orphan reaction in the pentose phosphate pathway, refocusing cellular metabolism to a high-redox state upon physiological or artificial downregulation. CARKL-dependent metabolic reprogramming is required for proper M1- and ... |
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TMPJ-00973
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EIF1AX Protein, Human, Recombinant (His)
eIF-1A X Isoform,Eukaryotic Translation Initiation Factor 1A...
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Human
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E. coli
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Eukaryotic Translation Initiation Factor 1A, X-Chromosomal (EIF1AX) is an essential eukaryotic translation initiation factor that belongs to the eIF-1A family. EIF1AX is required for the binding of the 43S complex (a 40S subunit, eIF2/GTP/Met-tRNAi and eIF3) to the 5' end of capped RNA and has been shown to interact with IPO13. EIF1AX contains one S1-like domain and seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the bind... |
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