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Perfluorohexane (AF-0150) 是一种基于全氟化碳 (PFC) 的微泡制剂,是超声造影剂,具有发育毒性,可通过 NMDA 受体介导的 PKC-ERK/AMPK 信号通路诱导记忆障碍和神经蛋白下调。Perfluorohexane 干扰小鼠的发情周期、排卵率、卵母细胞通讯和钙稳态。

Perfluorohexane (AF-0150) 是一种基于全氟化碳 (PFC) 的微泡制剂,是超声造影剂,具有发育毒性,可通过 NMDA 受体介导的 PKC-ERK/AMPK 信号通路诱导记忆障碍和神经蛋白下调。Perfluorohexane 干扰小鼠的发情周期、排卵率、卵母细胞通讯和钙稳态。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 5 g | ¥ 185 | In stock | |
| 10 g | ¥ 297 | In stock |
| 产品描述 | Perfluorohexane (AF-0150), a perfluorocarbon (PFC)-based microbubble formulation, is an ultrasound contrast agent with developmental toxicity that induces memory deficits and neuroprotein downregulation through the NMDA receptor-mediated PKC-ERK/AMPK signaling pathway.Perfluorohexane interferes with estrous cycle, ovulation rate in mice, Perfluorohexane interferes with estrous cycle, ovulation rate, oocyte communication and calcium homeostasis in mice. |
| 别名 | AF-0150, AF0150 |
| 分子量 | 338.04 |
| 分子式 | C6F14 |
| CAS No. | 355-42-0 |
| Smiles | FC(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F |
| 密度 | 1.669 g/cm3 at 25℃ (lit.) |
| 存储 | store at -20°C | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||||||||||||
| 溶解度信息 | DMSO: 80 mg/mL (236.66 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
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DMSO
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