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GPX4-IN-15(Compound C1)作为GPX4抑制剂,1 μM浓度下抑制GPX4活性达19.8%。此外,GPX4-IN-15对癌细胞株MDA-MB-468、BT-549及MDA-MB-231表现出明显的抑制作用,其IC50值分别为0.86 μM、0.96 μM和0.48 μM。
GPX4-IN-15(Compound C1)作为GPX4抑制剂,1 μM浓度下抑制GPX4活性达19.8%。此外,GPX4-IN-15对癌细胞株MDA-MB-468、BT-549及MDA-MB-231表现出明显的抑制作用,其IC50值分别为0.86 μM、0.96 μM和0.48 μM。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
10 mg | 询价 | 10-14周 | |
50 mg | 询价 | 10-14周 |
产品描述 | GPX4-IN-15 (Compound C1) is an inhibitor of GPX4, demonstrating an inhibition rate of 19.8% at a concentration of 1 μM. This compound effectively inhibits the proliferation of cancer cell lines MDA-MB-468, BT-549, and MDA-MB-231, with IC50 values of 0.86 μM, 0.96 μM, and 0.48 μM respectively. |
分子量 | 368.21 |
分子式 | C17H15Cl2NO4 |
CAS No. | 3032966-42-7 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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