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388

抑制剂 & 化合物

79

天然产物

4

化合物库

101

重组蛋白

9

同位素标记化合物

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Cat. No.	Product Name
L2195	抗前列腺癌化合物库		2070 compounds
	2070 种与前列腺癌相关的化合物，可以用于高通量和高内涵筛选
L4300	Wnt/Hedgehog/Notch 通路化合物库		237 compounds
	237 个Wnt & Hedgehog & Notch 靶点相关的生物活性小分子化合物的特有集合，用于相关通路的研究及药物的筛选，可用于高通量、高内涵筛选。
L2192	抗胰腺癌化合物库		2238 compounds
	2238 种与胰腺癌相关的化合物，可以用于高通量和高内涵筛选；
L8710	铜死亡化合物库		400 compounds
	TargetMol 铜死亡化合物库集合了 400 种与铜死亡相关的化合物，可以用于铜死亡机制及相关疾病研究

化合物库

抗前列腺癌化合物库

Cat.No: L2195

Compounds: 2070

Wnt/Hedgehog/Notch 通路化合物库

Cat.No: L4300

Compounds: 237

抗胰腺癌化合物库

Cat.No: L2192

Compounds: 2238

铜死亡化合物库

Cat.No: L8710

Compounds: 400

Cat. No.	Product Name	Target	Signaling Pathways
T80552	Prostate Specific Antigen Substrate
	Prostate Specific Antigen Substrate为前列腺特异性抗原（PSA）的荧光底物，专用于检测PSA的酶活性。
T23189	prostate apoptosis response protein PAR-4 (2-7) [Homo sapiens]	Others	Others
	Prostate apoptosis response protein PAR-4 (2-7) [Homo sapiens] is a peptide with the sequence H2N-Ala-Thr-Gly-Gly-Tyr-Arg-OH, MW= 623.66.
T22263	Bavdegalutamide ARV-110	Androgen Receptor	Endocrinology/Hormones
	Bavdegalutamide (ARV-110) 是一种雄激素受体 (AR) 的 PROTAC 降解剂。 Bavdegalutamide 可用于前列腺癌的研究。 Bavdegalutamide 具有口服活性和选择性，并促进 AR 的泛素化和降解。
T0380	Bicalutamide 比卡鲁胺,ICI-176334	Androgen Receptor; Autophagy	Autophagy; Endocrinology/Hormones
	Bicalutamide (ICI-176334) 是一种具有口服活性的非甾体雄激素受体拮抗剂，可研究前列腺癌。
T7690	2-hydroxy Flutamide	Androgen Receptor	Endocrinology/Hormones
	2-hydroxy Flutamide 是 Flutamide 的活性代谢物，是雄激素受体拮抗剂，其 IC50值为700 nM。它可用于研究前列腺癌。
T60051	VPC-18005	Others	Others
	VPC-18005 是一种荧光素酶抑制剂。 VPC-18005 抑制 ERG 诱导的转录并直接与 ERG-ETS 结构域相互作用，从而破坏 ERG 与 DNA 的结合。
T8858	DTHIB	HSP	Cytoskeletal Signaling; Metabolism
	DTHIB 是一种选择性热休克蛋白 1 的直接抑制剂，与 HSF1 DNA 结合域结合的Kd 为 160 nM。它选择性刺激核HSF1的降解，强烈抑制 HSF1 癌症基因特征和前列腺癌细胞增殖。
T3160	HUHS015	Others	Others
	HUHS015 是高效的PCA-1/ALKBH3抑制剂。它对 PCA-1 作用的IC50值为 0.67 μM。
T21740	RD162	Androgen Receptor	Endocrinology/Hormones
	RD162 是一种与雄激素受体 (AR) 特异性结合的非甾体抗雄激素 (NSAA)。
T8217	Enzalutamide carboxylic acid	Androgen Receptor; Drug Metabolite	Endocrinology/Hormones; Metabolism
	Enzalutamide carboxylic acid 是 Enzalutamide 非活性代谢物。Enzalutamide 是雄激素受体 (AR) 拮抗剂。
T9721	ML339	CXCR	Autophagy; GPCR/G Protein; Immunology/Inflammation
	ML339 是有效的CXCR6选择性拮抗剂，IC50为 140 nM。ML339 对 CXCR5，CXCR4，CCR6 和 Apelin 受体 (APJ) 无拮抗作用，IC50>79 μM。ML339 在前列腺癌研究领域有研究的价值。
T9266	Fatostatin	Lipid; Fatty Acid Synthase	Metabolism
	Fatostatin A 是一种SREBP 活化的特异性抑制剂，能够抑制 SREBP-1 和 SREBP-2 的活化。它与 SCAP (SREBP 裂解激活蛋白) 结合，抑制 SREBPs 的 ER-Golgi 易位。它具有抗肿瘤活性，能抑制ob/ob 小鼠的高血糖。它抑制细胞中成脂基因的转录。
T39695	ARD-2128	Androgen Receptor; PROTACs	Endocrinology/Hormones; PROTAC
	ARD-2128 是高效的雄激素受体降解剂 PROTAC。它可有效降低雄激素受体蛋白并抑制肿瘤组织中雄激素受体调节的基因，在没有毒性迹象的情况下抑制肿瘤生长。它有用于前列腺癌研究的价值。
T12928	SK33	Androgen Receptor	Endocrinology/Hormones
	SK33 是一种有效的组织选择性抗雄激素药物，是一种肌醇类似物，能够降低雄激素受体 (AR) 的转录活性。
T25492	Hepln-13 Hepln 13,Hepln13	c-Met/HGFR	Tyrosine Kinase/Adaptors
	Hepln-13 是具有口服活性的Hepsin 抑制剂(IC50:0.33 µM)。它可用于研究转移性前列腺癌。
T6889	MI-136	Apoptosis; Epigenetic Reader Domain; Androgen Receptor	Apoptosis; Chromatin/Epigenetic; Endocrinology/Hormones
	MI136 是 menin-MLL(PPI) 蛋白互作的抑制剂，其 IC50值为31 nM，Kd 值为23.6 nM。它可抑制 DHT 诱导的雄激素受体 (AR) 靶基因的表达，有用于去势抵抗性肿瘤的潜能。
T6002	Enzalutamide MDV3100,恩杂鲁胺	Androgen Receptor; Autophagy	Autophagy; Endocrinology/Hormones
	Enzalutamide (MDV3100) 是一种雄激素受体 (AR) 拮抗剂 (IC50=36 nM in LNCaP)。Enzalutamide 可以激活自噬，具有抗肿瘤活性，常用于去势抵抗性前列腺癌的治疗。
T6400	AZD3514	Androgen Receptor	Endocrinology/Hormones
	AZD3514 是一种口服雄激素受体下调剂(Ki :2.2 μM)，能够减少 AR 蛋白表达。
T13273	UT-34	Androgen Receptor	Endocrinology/Hormones
	UT-34 是选择性的、具有口服活性的泛雄激素受体拮抗剂和降解剂，能够作用于野生型 AR (IC50:211.7 nM)、F876L-AR (IC50:262.4 nM)、W741L-AR (IC50:215.7 nM)。它与配体结合结构域和功能 1结构域结合，并需要泛素蛋白酶体途径来降解AR。它有抗前列腺癌的能力。
T2014	CCG-1423 CCG1423	LRRK2; Rho; Ras	Autophagy; Cell Cycle/Checkpoint; GPCR/G Protein; MAPK
	CCG-1423 是一种选择性 RhoA 通路抑制剂，可抑制 SRF 介导的转录，能抑制细胞的转移前列腺癌PC-3细胞侵袭模型。
T38684	AKR1C3-IN-4 AKR1C3-IN-4	NADPH	Metabolism
	AKR1C3-IN-4 是醛酮还原酶 1C3 (AKR1C3) 选择性抑制剂，IC50为 0.56 μM。它在去势抵抗性前列腺癌中有研究的价值。
T1855	ZCL278 ZCL 278	CDK; Ras	Cell Cycle/Checkpoint; GPCR/G Protein; MAPK
	ZCL278 是一种选择性 Cdc42 GTPase 抑制剂，与Cdc42结合，Kd 为 11.4 μM。
T10717	Inobrodib CBP-IN-1	Epigenetic Reader Domain	Chromatin/Epigenetic
	Inobrodib (CBP-IN-1) 是一种口服活性的强选择性p300/CBP 抑制剂，与 p300 和 CBP 结合，Kd 值为 1.3 和 1.7 nM。它抑制前列腺癌细胞系的细胞增殖并降低雄激素受体和 C-MYC 调节的基因表达。
T28410	PHPS1 PHPS-1,PHPS 1	Phosphatase	Metabolism
	PHPS1 是 Shp2的选择性抑制剂，对 Shp2，Shp2-R362K，Shp1，PTP1B 和 PTP1B-Q 的 Ki 分别为 0.73，5.8，10.7，5.8 和 0.47 μM。
T9246	JNJ-63576253	Androgen Receptor	Endocrinology/Hormones
	JNJ63576253 是具有口服活性的、有效的雄激素受体的完全拮抗剂，在 LNCaP 细胞中对 F877L 突变型 AR 和野生型 AR 的IC50值分别为 37 和 54 nM。它可用于研究去势抵抗性前列腺癌。
T2108	Andarine S-4,GTx-007	Androgen Receptor	Endocrinology/Hormones
	Andarine (GTx-007) 是一种选择性的、具有口服活性的、非甾体受体雄激素受体(AR)调节剂 (SARM) 和部分激动剂，Ki=4 nM。它是一种具有较强活性的、具有组织选择性的 SARM。
T0272	Nilutamide 尼鲁米特,RU23908	Androgen Receptor	Endocrinology/Hormones
	Nilutamide (RU23908) 是一种非甾体抗雄激素药物，有用于转移性前列腺癌的潜力。
T6916	OICR-9429 OICR 9429	Histone Methyltransferase; JAK	Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells
	OICR-9429 是一个新颖的相互作用的小分子Wdr5-MLL 拮抗剂，IC50是 5 uM，在体外抑制急性髓性白血病细胞。
T16522	Phenoxodiol 脱氢雌马酚,Dehydroequol,Idronoxil,Haginin E	Apoptosis; IAP; Caspase; Topoisomerase; p53	Apoptosis; DNA Damage/DNA Repair; Proteases/Proteasome
	Phenoxodiol (Idronoxil) 是合成genestein 的类似物，激活线粒体caspase 系统，抑制XIAP，使癌细胞对fas 介导的凋亡敏感。它在细胞周期的G1/S 期诱导细胞周期阻滞，通过独立于p53的方式上调p21WAF1。它通过稳定可分裂复合物抑制DNA 拓扑异构酶II，从而阻止DNA 复制。
T1267	Abacavir Epzicom,Ziagen,阿巴卡韦	Apoptosis; HIV Protease; Reverse Transcriptase	Apoptosis; Microbiology/Virology; Proteases/Proteasome
	Abacavir (Ziagen) 是一种核苷类似物逆转录酶抑制剂。
T6308	Stattic STAT3 Inhibitor V	Apoptosis; STAT	Apoptosis; JAK/STAT signaling; Stem Cells
	Stattic (STAT3 Inhibitor V) 是一种 STAT3 抑制剂 (IC50=5.1 μM)，选择性地抑制 STAT3 活化、二聚化和核转位。Stattic 具有抗肿瘤活性，可诱导细胞凋亡。
T27730	KGP94 KGP-94,KGP 94	Cysteine Protease	Proteases/Proteasome
	KGP94 是一种有效的、选择性的和竞争性的溶酶体内肽酶抑制剂。
T36841	IPI-9119	Fatty Acid Synthase	Metabolism
	IPI-9119 是一种具有口服活性、选择性和不可逆的 FASN 抑制剂 (IC50 = 0.3 nM)。
T7188	Piclidenoson CF-101,IB-MECA	Apoptosis; Adenosine Receptor	Apoptosis; GPCR/G Protein; Neuroscience
	Piclidenoson (CF-101) 是一种具有口服活性的，选择性的腺苷 A3 受体激动剂。它在不同类型的癌细胞如黑色素瘤、白血病中表现出抗增殖和诱导凋亡的作用，可研究自身免疫性炎症疾病和 COVID-19。
T1448	Dasatinib BMS-354825,达沙替尼	Apoptosis; Bcr-Abl; Src; c-Kit; Autophagy	Angiogenesis; Apoptosis; Autophagy; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors
	Dasatinib (BMS-354825) 是一种酪氨酸激酶抑制剂，抑制 Src 和 Bcr-Abl (Ki=16/30 pM)，具有口服活性和 ATP 竞争性。Dasatinib 具有抗肿瘤活性，用于治疗白血病和淋巴瘤等。
T0696	Naftopidil KT-611,萘哌地尔,BM-15275	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Naftopidil (KT-611) 是一种选择性的 alpha1-肾上腺素受体 (α1-adrenoceptor) 拮抗剂，对克隆的人类 α1a、α1b 和 α1d 亚型肾上腺素受体的亲和力Ki 分别为 3.7 nM、20 nM 、1.2 nM。它具有抗增殖活性，可用于研究前列腺增生。
T20681	Estramustine NSC-89201,NSC 89201,LEO 275,LEO275,雌莫司汀,NSC89201,LEO-275	Microtubule Associated	Cytoskeletal Signaling
	Estramustine (LEO-275) 是一种与雌二醇相连的氮芥，通常为磷酸盐。它已被用于治疗前列腺肿瘤；还具有防辐射功能。它被前列腺细胞选择性吸收，并通过干扰微管动力学和降低血浆睾酮水平发挥抗肿瘤作用。
T9179	CLP-3094 2-([2-(4-CHLOROPHENOXY)ETHYL]THIO)-1H-BE	Androgen Receptor	Endocrinology/Hormones
	CLP-3094 (2-([2-(4-CHLOROPHENOXY)ETHYL]THIO)-1H-BE) 是一种雄激素受体 BF3(binding function 3) 抑制剂，是一种选择性GPR142拮抗剂。BF3-IN-1 抑制 AR 转录活性 (IC50:4 μM)。
T3630	Relugolix RVT-601,瑞卢戈利,TAK-385	GNRH Receptor	GPCR/G Protein
	Relugolix (RVT-601) 是口服有活性的非肽性促性腺激素释放激素的拮抗剂。同 TAK-013 相比，它对人和猴子的受体具有高亲和力和强拮抗活性，它们的 IC50值分别为0.33 nM 和0.32 nM。它可用于研究性激素依赖性疾病，如子宫肌瘤、子宫内膜异位症、前列腺癌等。
T1167	Cyproterone acetate Androcur,醋酸环丙氯地孕酮,Cyproterone 17-O-acetate,醋酸环丙孕酮	Androgen Receptor	Endocrinology/Hormones
	Cyproterone acetate (Cyproterone 17-O-acetate) 是能够抗雄激素(IC50=7.1 nM) 和孕激素合成的类固醇。它与 progesteron 和糖皮质激素受体有亲和力。
T8933	JNJ-63576253 free base TRC253,JNJ-63576253	Androgen Receptor	Endocrinology/Hormones
	JNJ-63576253 free base (TRC253) 是具有口服活性的、有效的雄激素受体的完全拮抗剂，在 LNCaP 细胞中对 F877L 突变型 AR 和野生型 AR 的 IC50值分别为 37 和 54 nM。它可用于研究去势抵抗性前列腺癌 (CRPC) 。
T6367	Abacavir sulfate Abacavir Hemisulfate,硫酸阿巴卡韦,1592U89,ABC sulfate,Ziagen	Apoptosis; HIV Protease; Reverse Transcriptase	Apoptosis; Microbiology/Virology; Proteases/Proteasome
	Abacavir sulfate (Ziagen) 是一种核苷类似物逆转录酶抑制剂，可用于 HIV 和 AIDS。
T2275	YK-4-279 4,7-二氯-1,3-二氢-3-羟基-3-[2-(4-甲氧基苯基)-2-氧代乙基]-2H-吲哚-2-酮	Apoptosis; DNA/RNA Synthesis	Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	YK 4-279是一种RNA 解旋酶A 与致癌转录因子EWS-FLI1结合抑制剂，能抑制ESFT 细胞增长，诱导凋亡。
T6832	Fatostatin hydrobromide Fatostatin HBr,Fatostatin A,Fatostatin A HBr,Fatostatin	NPC1L1; Fatty Acid Synthase	Membrane transporter/Ion channel; Metabolism
	Fatostatin hydrobromide (Fatostatin A HBr) 是一种 SREBP 活化的特异性抑制剂，可抑制 SREBP-1 和 SREBP-2 的活化。它与 SCAP (SREBP 裂解激活蛋白) 结合，抑制 SREBPs 的 ER-Golgi 易位。它具有抗肿瘤作用，能抑制 ob/ob 小鼠的高血糖。它抑制了细胞中成脂基因的转录。
T9245	TRPM4-IN-1 CBA,4-chloro-2-(2-(2-chlorophenoxy)acetamido)benzoic acid	TRP/TRPV Channel	Membrane transporter/Ion channel
	TRPM4-IN-1 (4-chloro-2-(2-(2-chlorophenoxy)acetamido)benzoic acid) 是一种有效的阳离子通道TRPM4选择性抑制剂，IC50为 1.5 μM。TRPM4-IN-1 在心脏病和前列腺癌中具有研究价值。
T6600	Naftopidil dihydrochloride KT-611,KT-611 2HCl,盐酸萘哌地尔,Naftopidil DiHCl	5-HT Receptor; Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Naftopidil dihydrochloride (KT-611 2HCl) 是一种选择性的 alpha1-肾上腺素受体 (α1-adrenoceptor) 拮抗剂，对克隆的人类 α1a、α1b 和 α1d 亚型肾上腺素受体的亲和力Ki 分别为 3.7 nM、20 nM、1.2 nM。它具有抗增殖活性，可用于研究前列腺增生。
T1448L	Dasatinib monohydrate 达沙替尼,BMS-354825 Monohydrate	Apoptosis; Bcr-Abl; Src; c-Kit; Ephrin Receptor; Autophagy	Angiogenesis; Apoptosis; Autophagy; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors
	Dasatinib monohydrate (BMS-354825 Monohydrate) 是一种具有口服活性的，ATP 竞争性的双重Src/Bcr-Abl 抑制剂，有抗肿瘤活性，还诱导凋亡和自噬。它抑制Src 和Bcr-Abl 的IC50分别为 0.5 nM 和 <1.0 nM，Ki 值分别为 16 pM 和 30 pM。
T20789	S-23 (S)-3-(4-chloro-3-fluorophenoxy)-N-(4-cyano-3-(trifluoromethyl)phenyl)-2-hydroxy-2-methylpropanamide,S23	Androgen Receptor	Endocrinology/Hormones
	S-23 ((S)-3-(4-chloro-3-fluorophenoxy)-N-(4-cyano-3-(trifluoromethyl)phenyl)-2-hydroxy-2-methylpropanamide) 是口服选择性雄激素受体调节剂(Ki:1.7 nM)。它能够诱导 CV-1 细胞雄激素受体介导的转录激活，提高去势大鼠前列腺、精囊和肛提肌重量。
T4451	Estramustine phosphate sodium Ro 21-8837/001,Estramustine phosphate disodium,雌莫司汀磷酸钠	Apoptosis; Microtubule Associated	Apoptosis; Cytoskeletal Signaling
	Estramustine phosphate sodium (Ro 21-8837/001) 是雌二醇类似物，是一种具有口服活性抗微管化疗剂，通过与微管相关蛋白和微管蛋白结合而使微管解聚。它可诱导前列腺癌细胞凋亡，可研究前列腺癌。
T4102	Goserelin acetate 醋酸戈舍瑞林,Fertilan,ICI-118630 acetate,Zoladex	Apoptosis; GNRH Receptor	Apoptosis; GPCR/G Protein
	Goserelin acetate (Fertilan) 是一种促性腺激素释放激素 (GnRH/LHRH) 十肽类似物，能作为GnRH 激动剂。它可研究乳腺癌、上皮性卵巢癌和前列腺癌。

化合物

Prostate Specific Antigen Substrate

Cat.No: T80552

prostate apoptosis response protein PAR-4 (2-7) [Homo sapiens]

Cat.No: T23189

Target: Others

Bavdegalutamide

Cat.No: T22263

Synonym: ARV-110

Target: Androgen Receptor

Cat.No: T0380

Synonym: 比卡鲁胺,ICI-176334

Target: Androgen Receptor, Autophagy

2-hydroxy Flutamide

Cat.No: T7690

Target: Androgen Receptor

Cat.No: T60051

Target: Others

Cat.No: T8858

Target: HSP

Cat.No: T3160

Target: Others

Cat.No: T21740

Target: Androgen Receptor

Enzalutamide carboxylic acid

Cat.No: T8217

Target: Androgen Receptor, Drug Metabolite

Cat.No: T9721

Target: CXCR

Cat.No: T9266

Target: Lipid, Fatty Acid Synthase

Cat.No: T39695

Target: Androgen Receptor, PROTACs

Cat.No: T12928

Target: Androgen Receptor

Cat.No: T25492

Synonym: Hepln 13,Hepln13

Target: c-Met/HGFR

Cat.No: T6889

Target: Apoptosis, Epigenetic Reader Domain, Androgen Receptor

Cat.No: T6002

Synonym: MDV3100,恩杂鲁胺

Target: Androgen Receptor, Autophagy

Cat.No: T6400

Target: Androgen Receptor

Cat.No: T13273

Target: Androgen Receptor

Cat.No: T2014

Synonym: CCG1423

Target: LRRK2, Rho, Ras

Cat.No: T38684

Synonym: AKR1C3-IN-4

Target: NADPH

Cat.No: T1855

Synonym: ZCL 278

Target: CDK, Ras

Cat.No: T10717

Synonym: CBP-IN-1

Target: Epigenetic Reader Domain

Cat.No: T28410

Synonym: PHPS-1,PHPS 1

Target: Phosphatase

Cat.No: T9246

Target: Androgen Receptor

Cat.No: T2108

Synonym: S-4,GTx-007

Target: Androgen Receptor

Cat.No: T0272

Synonym: 尼鲁米特,RU23908

Target: Androgen Receptor

Cat.No: T6916

Synonym: OICR 9429

Target: Histone Methyltransferase, JAK

Cat.No: T16522

Synonym: 脱氢雌马酚,Dehydroequol,Idronoxil,Haginin E

Target: Apoptosis, IAP, Caspase, Topoisomerase, p53

Cat.No: T1267

Synonym: Epzicom,Ziagen,阿巴卡韦

Target: Apoptosis, HIV Protease, Reverse Transcriptase

Cat.No: T6308

Synonym: STAT3 Inhibitor V

Target: Apoptosis, STAT

Cat.No: T27730

Synonym: KGP-94,KGP 94

Target: Cysteine Protease

Cat.No: T36841

Target: Fatty Acid Synthase

Cat.No: T7188

Synonym: CF-101,IB-MECA

Target: Apoptosis, Adenosine Receptor

Cat.No: T1448

Synonym: BMS-354825,达沙替尼

Target: Apoptosis, Bcr-Abl, Src, c-Kit, Autophagy

Cat.No: T0696

Synonym: KT-611,萘哌地尔,BM-15275

Target: Adrenergic Receptor

Cat.No: T20681

Synonym: NSC-89201,NSC 89201,LEO 275,LEO275,雌莫司汀,NSC89201,LEO-275

Target: Microtubule Associated

Cat.No: T9179

Synonym: 2-([2-(4-CHLOROPHENOXY)ETHYL]THIO)-1H-BE

Target: Androgen Receptor

Cat.No: T3630

Synonym: RVT-601,瑞卢戈利,TAK-385

Target: GNRH Receptor

Cyproterone acetate

Cat.No: T1167

Synonym: Androcur,醋酸环丙氯地孕酮,Cyproterone 17-O-acetate,醋酸环丙孕酮

Target: Androgen Receptor

JNJ-63576253 free base

Cat.No: T8933

Synonym: TRC253,JNJ-63576253

Target: Androgen Receptor

Abacavir sulfate

Cat.No: T6367

Synonym: Abacavir Hemisulfate,硫酸阿巴卡韦,1592U89,ABC sulfate,Ziagen

Target: Apoptosis, HIV Protease, Reverse Transcriptase

Cat.No: T2275

Synonym: 4,7-二氯-1,3-二氢-3-羟基-3-[2-(4-甲氧基苯基)-2-氧代乙基]-2H-吲哚-2-酮

Target: Apoptosis, DNA/RNA Synthesis

Fatostatin hydrobromide

Cat.No: T6832

Synonym: Fatostatin HBr,Fatostatin A,Fatostatin A HBr,Fatostatin

Target: NPC1L1, Fatty Acid Synthase

Cat.No: T9245

Synonym: CBA,4-chloro-2-(2-(2-chlorophenoxy)acetamido)benzoic acid

Target: TRP/TRPV Channel

Naftopidil dihydrochloride

Cat.No: T6600

Synonym: KT-611,KT-611 2HCl,盐酸萘哌地尔,Naftopidil DiHCl

Target: 5-HT Receptor, Adrenergic Receptor

Dasatinib monohydrate

Cat.No: T1448L

Synonym: 达沙替尼,BMS-354825 Monohydrate

Target: Apoptosis, Bcr-Abl, Src, c-Kit, Ephrin Receptor, Autophagy

Cat.No: T20789

Synonym: (S)-3-(4-chloro-3-fluorophenoxy)-N-(4-cyano-3-(trifluoromethyl)phenyl)-2-hydroxy-2-methylpropanamide,S23

Target: Androgen Receptor

Estramustine phosphate sodium

Cat.No: T4451

Synonym: Ro 21-8837/001,Estramustine phosphate disodium,雌莫司汀磷酸钠

Target: Apoptosis, Microtubule Associated

Goserelin acetate

Cat.No: T4102

Synonym: 醋酸戈舍瑞林,Fertilan,ICI-118630 acetate,Zoladex

Target: Apoptosis, GNRH Receptor

Cat. No.	Product Name	Target	Signaling Pathways
TN7020	Astragenol	Others	Others
	Astragenol 是合成黄芪醇衍生物的中间体。它的衍生物具有抗炎作用，可用于前列腺癌的研究。
T8188	Podophyllotoxone	Others; Microtubule Associated	Cytoskeletal Signaling; Others
	Podophyllotoxone 是从八角莲根中分离得到的一种天然产物，能抑制微管蛋白聚合，具有抗癌活性。
TN2097	Pomolic acid 坡模酸	Apoptosis; Caspase; HIV Protease; AMPK	Apoptosis; Chromatin/Epigenetic; Microbiology/Virology; PI3K/Akt/mTOR signaling; Proteases/Proteasome
	Pomolic acid 是从野鸦椿中分离出来的一种五环三萜烯。它抑制肿瘤细胞的生长，诱导细胞凋亡，有用于前列腺癌的潜力。
T1134	Clofoctol 叔辛酚氯,氯福克酚	Antibacterial; Antibiotic	Microbiology/Virology
	Clofoctol 是一种抗生素,，可研究革兰氏阳性菌感染。它仅对革兰氏阳性菌起作用, 可渗透入人类肺组织。
T3324	Lycorine Galanthidine,Narcissine,石蒜碱,Amarylline,Belamarine,Licorine,番石榴碱	Apoptosis; Virus Protease; Antibacterial; AChR; Fatty Acid Synthase	Apoptosis; Metabolism; Microbiology/Virology; Neuroscience
	Lycorine (Narcissine) 是从金眼科植物科中提取的一种天然生物碱。它是一种具有口服活性的SCAP 抑制剂，Kd 值 15.24 nM。它也是黑色素瘤血管生成抑制剂，有用于前列腺癌和代谢疾病的研究潜力。
T3384	Wedelolactone 蟛蜞菊内酯,IKK Inhibitor II	Apoptosis; NF-κB; Lipoxygenase; Caspase	Apoptosis; Metabolism; NF-κB; Proteases/Proteasome
	Wedelolactone (IKK Inhibitor II) 是来自旱莲草的一种天然产物，通过阻断 IκBα 的磷酸化和降解来抑制细胞中 NF-κB 介导的基因转录，具有抗癌，抗炎和抗氧化活性。
T2939	Forskolin 毛喉素,Coleonol,Colforsin	FXR; Adenylyl cyclase; AChR; Autophagy	Autophagy; Metabolism; Neuroscience
	Forskolin (Coleonol) 属于天然产物，是一种腺苷酸环化酶激活剂 (EC50=0.5 μM)。Forskolin 可以增加 cAMP 水平，可以激活 PXR 和 FXR，也可以诱导细胞自噬。Forskolin 对心脏产生正性肌力作用，具有血小板抗凝集和降压作用。
T3878	Raddeanin A NSC382873,竹节香附素A,Anemodeanin A,Raddeanin R3	Apoptosis; HDAC	Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair
	Raddeanin A (NSC-382873) 是竹节香附中的一种天然三萜皂苷，可抑制组蛋白去乙酰化酶，具有很强的抗血管生成能力和抗肿瘤活性。
T4S1173	Agrimol B 仙鹤草酚B,仙鹤草酚 B	Sirtuin; PPAR	Chromatin/Epigenetic; DNA Damage/DNA Repair; Metabolism
	Agrimol B 是从仙鹤草中分离得到的一种多酚衍生物，可抑制脂肪形成，降低PPARγ的表达，诱导SIRT1易位和表达。
T6485	Embelin NSC 91874,恩贝酸,恩贝酸/恩贝灵,Emberine,Embelic acid	Apoptosis; NF-κB; Lipoxygenase; IAP; Prostaglandin Receptor; Autophagy	Apoptosis; Autophagy; GPCR/G Protein; Immunology/Inflammation; Metabolism; NF-κB
	Embelin (Embelic acid) 是从日本 Ardisia 草药中分离出来的一种非肽类细胞渗透性XIAP 抑制剂，诱导口腔鳞癌细胞自噬和凋亡。它阻断 NF-kappaB 信号通路，从而抑制 NF-kappaB 调节的抗凋亡和转移基因产物。在高水平 XIAP 的前列腺癌细胞中抑制细胞生长，诱导凋亡，并激活 caspase-9。
T2S1158	4,5-Dicaffeoylquinic acid 3,4-Dicaffeoylquinic acid,异绿原酸C(4,5),Isochlorogenic acid C	Others; HBV; Endogenous Metabolite	Metabolism; Microbiology/Virology; Others
	4,5-Dicaffeoylquinic acid (Isochlorogenic acid C) 是一种天然产物，有抗病毒、抗肝毒性活性。
T6290	Tanespimycin 坦螺旋霉素,17-AAG,CP 127374,NSC 330507,KOS 953	Apoptosis; Mitophagy; HSP; Antibacterial; Antibiotic; Autophagy	Apoptosis; Autophagy; Cytoskeletal Signaling; Metabolism; Microbiology/Virology
	Tanespimycin (KOS 953) 是一种 Hsp90 抑制剂，可选择性抑制 BT474 肿瘤细胞 Hsp90，IC50为 5 nM。它消耗细胞内 STK38/NDR1，并降低 STK38 激酶活性，还能下调stk38基因表达。
T2S1797	Santalol 檀香醇；白檀油萜醇;檀香脑,檀香醇	Antioxidant; Antifungal	Microbiology/Virology; oxidation-reduction
	Santalol 是一种檀香醇的 α 和 β-异构体混合物。其中α-santalol 分离自檀香油中，是一种有前途的抗癌药，能够预防口腔癌、前列腺癌、乳腺癌和皮肤癌。
T2895	Lupeol Fagarasterol,羽扇豆醇,Monogynol B,Clerodol,(3β,13ξ)-Lup-20(29)-en-3-ol,Farganasterol	Apoptosis; Androgen Receptor; Akt	Apoptosis; Cytoskeletal Signaling; Endocrinology/Hormones; PI3K/Akt/mTOR signaling
	Lupeol (Monogynol B) 是一个活跃的五环三萜，具有抗氧化剂、抗肿瘤和抗炎活性。它是一种雄激素受体抑制剂，可研究癌症，特别是雄激素依赖表型和去势抵抗表型的前列腺癌。
T34394	Rotenolone 12ALPHA-羟基鱼藤酮,Rotenolone I,12alpha-HYDROXYROTENONE	Others	Others
	Rotenolone (12alpha-HYDROXYROTENONE) 是鱼藤酮的代谢物，鱼藤酮是一种源自藤本植物和龙果属植物的天然化合物。
T4869	D-Allose 阿洛糖,β-D-Allopyranose,D-(+)-ALLOSE	Others; Endogenous Metabolite	Metabolism; Others
	D-Allose (β-D-Allopyranose) 是内源性代谢产物的一种。
T6S1255	Ophiopogonin-D 麦冬皂苷D	ROS	Immunology/Inflammation
	Ophiopogonin-D 通过 RIPK1 显着抑制前列腺细胞的体外和体内生长，OPD 可能被开发为潜在的抗前列腺癌药物。
T3329	4',7-Dimethoxyisoflavone 4',7-二甲氧基异黄酮,Dimethoxydaidzein,Daidzein dimethyl ether	Endogenous Metabolite; Antifungal	Metabolism; Microbiology/Virology
	4',7-Dimethoxyisoflavone (Daidzein dimethyl ether) 是从阔荚合欢中分离的黄酮类化合物，有抗真菌作用，可抑制大鼠前列腺睾酮5α-还原酶。
T7873	Iberverin	Others	Others
	Iberverin 是一种天然产品。它诱导 II 期酶活性并降低前列腺癌细胞中雄激素受体的表达。
T13518	5α-Pregnane-3β,6α-diol-20-one	Others	Others
	5α-Pregnane-3β,6α-diol-20-one 是促进有丝分裂的 progesterone 代谢物，可于血清不足时雄性激素反应的前列腺素癌细胞中产生。
TQ0214	Dimethylcurcumin ASC-J9,二甲基姜黄素,GO-Y025	Androgen Receptor	Endocrinology/Hormones
	Dimethylcurcumin (ASC-J9) 是雄激素受体降解增强剂，能够有效抑制耐药性前列腺癌细胞增殖和侵袭。
TN1745	Hosenkoside M (+)-Hosenkoside M	Others	Others
	Hosenkoside M是从凤仙花香脂种子中提取的巴扎烷糖苷，具有抗癌活性，可用于研究前列腺癌。
T2543	Cabazitaxel XRP6258,卡巴他塞,RPR-116258A,TXD 258,taxoid XRP6258	Microtubule Associated; Autophagy	Autophagy; Cytoskeletal Signaling
	Cabazitaxel (taxoid XRP6258) 是一种紫杉烷类的抗肿瘤剂，可用于治疗多西他赛失败后的去势抵抗性转移性前列腺癌。
T4767	Formamide 甲酰胺,Carbamaldehyde,Methanamide,NSC 748,Formimidic acid	Others; Endogenous Metabolite	Metabolism; Others
	Formamide (NSC-748) 是甲酸的酰胺衍生物，被用作许多离子化合物的溶剂。
T7990	9-hydroxy-4-androstene-3,17-dione	Others	Others
	9-hydroxy-4-androstene-3,17-dione 是一种类固醇激素，具有抗肿瘤活性，可以抑制多种癌症细胞的生长，包括乳腺癌、前列腺癌和肺癌细胞。
T25192	Butyrolactone I Olomoucin,丁酸内酯I	CDK	Cell Cycle/Checkpoint
	Butyrolactone I (Olomoucin) 是 CDK 和 cdc2 激酶家族的 ATP 竞争性抑制剂。 Butyrolactone I 在非小细胞肺、小细胞肺和前列腺癌细胞系中显示出抗肿瘤作用。
T5646	Cinnamic acid 3-Phenylacrylic acid,β-Phenylacrylic acid,肉桂酸	Endogenous Metabolite	Metabolism
	Cinnamic acid (β-Phenylacrylic acid) 在癌症干预中具有潜在的应用价值，对胶质母细胞瘤，黑色素瘤，前列腺癌，肺癌细胞的IC50=1-4.5 mM。
T4S2157	Campesterol 菜油甾醇,(24R)-5-Ergosten-3β-ol	Endogenous Metabolite	Metabolism
	Campesterol ((24R)-5-Ergosten-3β-ol) 是一种植物甾醇，具有降胆固醇和抗癌的活性。
TN1805	Isosilybin B	Apoptosis; Androgen Receptor	Apoptosis; Endocrinology/Hormones
	Isosilybin B 是一种从水飞蓟中提取的黄酮木脂素，具有抗前列腺癌 (PCA) 活性，对癌细胞增殖有抑制作用，促使 G1 期阻滞和凋亡。Isosilybin B 诱导雄激素受体降解。
T17280	(Z)-Guggulsterone	Apoptosis; VEGFR; Akt	Angiogenesis; Apoptosis; Cytoskeletal Signaling; PI3K/Akt/mTOR signaling; Tyrosine Kinase/Adaptors
	(Z)-Guggulsterone 是印度阿育吠陀药用植物Commiphora mukul 的成分，可通过引起细胞凋亡来抑制人前列腺癌细胞的生长，还可通过抑制VEGF-VEGF-R2-Akt 信号传导轴来抑制血管生成。
T6S1373	Casticin Quercetagetin 3,6,7,4'-Tetramethyl Ether,Vitexicarpin,蔓荆子黄素	STAT	JAK/STAT signaling; Stem Cells
	Casticin (Vitexicarpin) 是从蔓荆子中得到的一种甲氧基黄酮，可抑制STAT3的活化，具有抗有丝分裂和抗炎活性。
T14008	2,2,5,7,8-Pentamethyl-6-Chromanol PMC	Androgen Receptor	Endocrinology/Hormones
	2,2,5,7,8-Pentamethyl-6-Chromanol (PMC) 是维生素 E (α-tocopherol) 的抗氧化部分，能够有效的调节雄激素受体 (androgen receptor) 信号，及抗前列腺癌细胞系的抗癌活性。
TN2160	Roemerine (-)-Roemerine	Antibiotic	Microbiology/Virology
	Roemerine ((-)-Roemerine) 是一种来自塞内加尔番荔枝的卟啉生物碱，具有抗真菌和抗癌活性，通过抑制 Bmr 来防止小檗碱外排。Roemerine 以浓度依赖性方式增加细胞膜通透性，可用于研究真菌感染和前列腺癌。
T2795	Amygdalin 苦杏仁苷,Laetrile	Others	Others
	Amygdalin (Laetrile) 是一种植物葡萄糖苷，分离自蔷薇果实的果核中，如杏，桃，杏仁，樱桃和李子。
T3390	Obacunone	Apoptosis; Aromatase; p38 MAPK	Apoptosis; Endocrinology/Hormones; MAPK
	Obacunone 是从沼泽白葡萄柚种子中分离得到的，通过诱导凋亡发挥抗癌作用。它在雄激素依赖性人前列腺 Y 细胞中具有细胞毒性。它对鼠伤寒沙门氏菌具有抗毒作用，可作为开发鼠伤寒沙门氏菌抗毒策略的先导化合物。
TN1804	Isosilybin A 异水飞蓟素 A,异水飞蓟宾A,水飞蓟素 B2	Apoptosis; Tyrosinase; PPAR; ABC	Apoptosis; DNA Damage/DNA Repair; Membrane transporter/Ion channel; Metabolism; Proteases/Proteasome
	Isosilybin A 是从水飞蓟中分离出来的一种黄酮木脂素，可抑制癌细胞增殖并诱导 G1 期停滞和凋亡，通过靶向 Akt-NF-κB-雄激素受体轴激活前列腺癌细胞的凋亡机制，具有抗前列腺癌活性。
T3S0081	Oxypeucedanin (+-)-Oxypeucedanin,氧化前胡素,Oxypeucadanin	Potassium Channel	Membrane transporter/Ion channel
	Oxypeucedanin ((+-)-Oxypeucedanin) 是呋喃香豆素衍生物，分离自Angelica dahurica。它是选择性开放通道阻滞剂，可抑制hKv1.5通道电流，IC50值为 76 nM。它延长心脏动作电位持续时间，是潜在的抗心律失常试剂。它通过抑制癌细胞迁移来诱导细胞凋亡。
T4728	4-Acetamidobutanoic acid N-acetyl GABA,4-ACETAMIDOBUTYRIC ACID,4-乙酰氨基丁酸	GABA Receptor; Endogenous Metabolite; Antibacterial	Membrane transporter/Ion channel; Metabolism; Microbiology/Virology; Neuroscience
	4-Acetamidobutanoic acid (4-ACETAMIDOBUTYRIC ACID) 可在血液、粪便和尿液以及人体前列腺组织中找到，也存在于从酵母到人类的所有真核生物中。它是GABA 衍生物，具有抗氧化和抗菌活性。
T1660	Silibinin 水飞蓟宾 A,水飞蓟宾,Silibinin A,Silybin,Silymarin I	Reactive Oxygen Species; Autophagy	Autophagy; Immunology/Inflammation; Metabolism; NF-κB
	Silibinin (Silybin) 是水飞蓟的主要活性成分，具有抗癌和化疗预防作用，能抑制细胞增殖和迁移。
T4000	(±)-Equol Equol,(±)-雌马酚,(R,S)-Equol	Estrogen Receptor/ERR; Estrogen/progestogen Receptor; Drug Metabolite	Endocrinology/Hormones; Metabolism
	(±)-Equol ((R,S)-Equol) 是 equol 的外消旋体。它对 ERα 和 ERβ 的 EC50s of 分别为 200 和 74 nM。Equol 是大豆异黄酮黄豆苷和大豆黄素的代谢产物。
T3851	Vicenin 2 Vicenin -2,维采宁 2,新西兰牡荆苷	RAAS	Endocrinology/Hormones
	Vicenin 2 来源于广金钱草 (Desmodium styracifolium) 的地上部分。Vicenin 2 是一种血管紧张素转换酶 (ACE) 抑制剂，IC50=43.83 μM。
T6S0735	Flavokawain B 黄卡瓦胡椒素B,Flavokavain B,Flavokawin B,2'-Hydroxy-4',6'-Dimethoxychalcone	Apoptosis; Others	Apoptosis; Others
	Flavokawain B (Flavokavain B) 是从卡瓦醉椒的根提取物中，分离出的查尔酮。它是一种凋亡诱导剂，可抑制各种癌细胞株生长。它以极低的无毒浓度抑制人脑内皮细胞的迁移和血管形成，具有抗血管生成活性。
TMS0418	Dihydroergotoxine mesylate 甲磺酸二氢麦角碱,Ergoloid mesylates,甲磺酸双氢麦角毒碱	GABA Receptor	Membrane transporter/Ion channel; Neuroscience
	Dihydroergotoxine mesylate (Ergoloid mesylates) 是系列生物碱盐混合物，对GABAA 受体高结合活性。它主要用于改善与衰老相关的精神退化的症状和身体症状。
TN1013	Cucurbitacin D	Apoptosis	Apoptosis
	Cucurbitacin D 是一种从 Ecballium elaterium （L.）分离出来的三萜类化合物，具有抗癌抗肿瘤活性，抑制转移性 PrC 中的葡萄糖摄取和乳酸产生，诱导独立于 ERK1/2 激活的炎症小体激活。 Cucurbitacin D 是巨噬细胞中的一种新的炎症小体激活剂，通过调节 JAK/STAT3、PI3K/Akt/mTOR 和 MAPK 信号通路抑制 HepG2 细胞增殖并诱导细胞凋亡，可用于研究宫颈癌、白血病和前列腺癌。
T4S2126	Ginkgetin 银杏双黄酮,银杏素	Apoptosis; Wnt/beta-catenin; COX; STAT; Autophagy	Apoptosis; Autophagy; Cytoskeletal Signaling; Immunology/Inflammation; JAK/STAT signaling; Neuroscience; Stem Cells
	Ginkgetin 是从银杏叶中分离得到的一种双黄酮，具有抗肿瘤、抗炎、神经保护、抗真菌的作用。它也是 Wnt 信号抑制剂，IC50值为 5.92 μM。
T6491	(-)-(S)-Equol (−)-Equol,Equol,4',7-Dihydroxyisoflavan,4',7-Isoflavandiol,雌马酚	Estrogen Receptor/ERR; Estrogen/progestogen Receptor; Endogenous Metabolite	Endocrinology/Hormones; Metabolism
	(-)-(S)-Equol (4',7-Dihydroxyisoflavan) 是雌激素受体β的高亲和力配体。
T4S0797	Berberine 小檗碱,Berberin,Umbellatine,黄连素	Reactive Oxygen Species; Topoisomerase; Endogenous Metabolite; Antibacterial; Antibiotic; Autophagy	Autophagy; DNA Damage/DNA Repair; Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB
	Berberine (Umbellatine) 属于生物碱类天然产物，可以激活 AMPK、抑制 DNA 拓扑异构酶、诱导 ROS 生成。Berberine 具有抗肿瘤、抗菌、降血糖、降血脂等生物学活性。
TN3941	ent-17-Hydroxykaur-15-en-19-oic acid	Others	Others
	ent-17-Hydroxykaur-15-en-19-oic acid 是从香树叶中发现的天然化合物，对人前列腺细胞的IC50为17.63microg/mL。
TN5878	7,2',4'-Trihydroxy-5-methoxy-3-phenylcoumarin
	7,2',4'-Trihydroxy-5-methoxy-3-arylcoumarin shows activity in inhibiting prostate specific antigen (PSA) secreted from androgen dependent prostate cancer cell line, LNCaP cells.
TN3416	Angelol M	Others	Others
	Angelol M shows activity in inhibiting prostate specific antigen (PSA) secreted from androgen dependent prostate cancer cell line, LNCaP cells.
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天然产物

Cat.No: TN7020

Target: Others

Podophyllotoxone

Cat.No: T8188

Target: Others, Microtubule Associated

Cat.No: TN2097

Synonym: 坡模酸

Target: Apoptosis, Caspase, HIV Protease, AMPK

Cat.No: T1134

Synonym: 叔辛酚氯,氯福克酚

Target: Antibacterial, Antibiotic

Cat.No: T3324

Synonym: Galanthidine,Narcissine,石蒜碱,Amarylline,Belamarine,Licorine,番石榴碱

Target: Apoptosis, Virus Protease, Antibacterial, AChR, Fatty Acid Synthase

Cat.No: T3384

Synonym: 蟛蜞菊内酯,IKK Inhibitor II

Target: Apoptosis, NF-κB, Lipoxygenase, Caspase

Cat.No: T2939

Synonym: 毛喉素,Coleonol,Colforsin

Target: FXR, Adenylyl cyclase, AChR, Autophagy

Cat.No: T3878

Synonym: NSC382873,竹节香附素A,Anemodeanin A,Raddeanin R3

Target: Apoptosis, HDAC

Cat.No: T4S1173

Synonym: 仙鹤草酚B,仙鹤草酚 B

Target: Sirtuin, PPAR

Cat.No: T6485

Synonym: NSC 91874,恩贝酸,恩贝酸/恩贝灵,Emberine,Embelic acid

Target: Apoptosis, NF-κB, Lipoxygenase, IAP, Prostaglandin Receptor, Autophagy

4,5-Dicaffeoylquinic acid

Cat.No: T2S1158

Synonym: 3,4-Dicaffeoylquinic acid,异绿原酸C(4,5),Isochlorogenic acid C

Target: Others, HBV, Endogenous Metabolite

Cat.No: T6290

Synonym: 坦螺旋霉素,17-AAG,CP 127374,NSC 330507,KOS 953

Target: Apoptosis, Mitophagy, HSP, Antibacterial, Antibiotic, Autophagy

Cat.No: T2S1797

Synonym: 檀香醇；白檀油萜醇;檀香脑,檀香醇

Target: Antioxidant, Antifungal

Cat.No: T2895

Synonym: Fagarasterol,羽扇豆醇,Monogynol B,Clerodol,(3β,13ξ)-Lup-20(29)-en-3-ol,Farganasterol

Target: Apoptosis, Androgen Receptor, Akt

Cat.No: T34394

Synonym: 12ALPHA-羟基鱼藤酮,Rotenolone I,12alpha-HYDROXYROTENONE

Target: Others

Cat.No: T4869

Synonym: 阿洛糖,β-D-Allopyranose,D-(+)-ALLOSE

Target: Others, Endogenous Metabolite

Cat.No: T6S1255

Synonym: 麦冬皂苷D

Target: ROS

4',7-Dimethoxyisoflavone

Cat.No: T3329

Synonym: 4',7-二甲氧基异黄酮,Dimethoxydaidzein,Daidzein dimethyl ether

Target: Endogenous Metabolite, Antifungal

Cat.No: T7873

Target: Others

5α-Pregnane-3β,6α-diol-20-one

Cat.No: T13518

Target: Others

Dimethylcurcumin

Cat.No: TQ0214

Synonym: ASC-J9,二甲基姜黄素,GO-Y025

Target: Androgen Receptor

Cat.No: TN1745

Synonym: (+)-Hosenkoside M

Target: Others

Cat.No: T2543

Synonym: XRP6258,卡巴他塞,RPR-116258A,TXD 258,taxoid XRP6258

Target: Microtubule Associated, Autophagy

Cat.No: T4767

Synonym: 甲酰胺,Carbamaldehyde,Methanamide,NSC 748,Formimidic acid

Target: Others, Endogenous Metabolite

9-hydroxy-4-androstene-3,17-dione

Cat.No: T7990

Target: Others

Butyrolactone I

Cat.No: T25192

Synonym: Olomoucin,丁酸内酯I

Target: CDK

Cat.No: T5646

Synonym: 3-Phenylacrylic acid,β-Phenylacrylic acid,肉桂酸

Target: Endogenous Metabolite

Cat.No: T4S2157

Synonym: 菜油甾醇,(24R)-5-Ergosten-3β-ol

Target: Endogenous Metabolite

Cat.No: TN1805

Target: Apoptosis, Androgen Receptor

(Z)-Guggulsterone

Cat.No: T17280

Target: Apoptosis, VEGFR, Akt

Cat.No: T6S1373

Synonym: Quercetagetin 3,6,7,4'-Tetramethyl Ether,Vitexicarpin,蔓荆子黄素

Target: STAT

2,2,5,7,8-Pentamethyl-6-Chromanol

Cat.No: T14008

Synonym: PMC

Target: Androgen Receptor

Cat.No: TN2160

Synonym: (-)-Roemerine

Target: Antibiotic

Cat.No: T2795

Synonym: 苦杏仁苷,Laetrile

Target: Others

Cat.No: T3390

Target: Apoptosis, Aromatase, p38 MAPK

Cat.No: TN1804

Synonym: 异水飞蓟素 A,异水飞蓟宾A,水飞蓟素 B2

Target: Apoptosis, Tyrosinase, PPAR, ABC

Cat.No: T3S0081

Synonym: (+-)-Oxypeucedanin,氧化前胡素,Oxypeucadanin

Target: Potassium Channel

4-Acetamidobutanoic acid

Cat.No: T4728

Synonym: N-acetyl GABA,4-ACETAMIDOBUTYRIC ACID,4-乙酰氨基丁酸

Target: GABA Receptor, Endogenous Metabolite, Antibacterial

Cat.No: T1660

Synonym: 水飞蓟宾 A,水飞蓟宾,Silibinin A,Silybin,Silymarin I

Target: Reactive Oxygen Species, Autophagy

Cat.No: T4000

Synonym: Equol,(±)-雌马酚,(R,S)-Equol

Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor, Drug Metabolite

Cat.No: T3851

Synonym: Vicenin -2,维采宁 2,新西兰牡荆苷

Target: RAAS

Cat.No: T6S0735

Synonym: 黄卡瓦胡椒素B,Flavokavain B,Flavokawin B,2'-Hydroxy-4',6'-Dimethoxychalcone

Target: Apoptosis, Others

Dihydroergotoxine mesylate

Cat.No: TMS0418

Synonym: 甲磺酸二氢麦角碱,Ergoloid mesylates,甲磺酸双氢麦角毒碱

Target: GABA Receptor

Cat.No: TN1013

Target: Apoptosis

Cat.No: T4S2126

Synonym: 银杏双黄酮,银杏素

Target: Apoptosis, Wnt/beta-catenin, COX, STAT, Autophagy

Cat.No: T6491

Synonym: (−)-Equol,Equol,4',7-Dihydroxyisoflavan,4',7-Isoflavandiol,雌马酚

Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor, Endogenous Metabolite

Cat.No: T4S0797

Synonym: 小檗碱,Berberin,Umbellatine,黄连素

Target: Reactive Oxygen Species, Topoisomerase, Endogenous Metabolite, Antibacterial, Antibiotic, Autophagy

ent-17-Hydroxykaur-15-en-19-oic acid

Cat.No: TN3941

Target: Others

7,2',4'-Trihydroxy-5-methoxy-3-phenylcoumarin

Cat.No: TN5878

Cat.No: TN3416

Target: Others

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Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-00381	PSMA Protein, Human, Recombinant (His) FGCP,GCP2,PSMA,GCPII,NAALAdase,folate hydrolase (prostat...	Human	HEK293 Cells
	PSMA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 81.86 kDa and the accession number is Q04609-1.
TMPY-06655	PSCA Protein, Mouse, Recombinant (His & Avi), Biotinylated prostate stem cell antigen,2210408B04Rik	Mouse	HEK293 Cells
	PSCA Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 11.64 kDa and the accession number is P57096.
TMPY-06710	PSCA Protein, Mouse, Recombinant (His) prostate stem cell antigen,2210408B04Rik	Mouse	HEK293 Cells
	PSCA Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 9.83 kDa and the accession number is P57096.
TMPY-02155	Prostatic Acid Phosphatase Protein, Human, Recombinant (His) 5'-NT,acid phosphatase, prostate,PAP,ACP-3,ACP3	Human	HEK293 Cells
	Prostatic Acid Phosphatase Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42 kDa and the accession number is P15309-2.
TMPY-01390	PSMA Protein, Mouse, Recombinant (His) mopsm,folate hydrolase (prostate-specific membrane ...	Mouse	HEK293 Cells
	PSMA Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 81.8 kDa and the accession number is O35409.
TMPY-02672	Prostatic Acid Phosphatase Protein, Mouse, Recombinant (His) 5'-NT,9.104100899-104272570.1,Ppal,A030005E02Rik,PAP,Lap,aci...	Mouse	HEK293 Cells
	Prostatic Acid Phosphatase Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42 kDa and the accession number is Q8CE08-1.
TMPY-00133	PARM-1 Protein, Human, Recombinant (His) PARM-1,Cipar1,WSC4,prostate androgen-regulated muci...	Human	HEK293 Cells
	PARM-1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.7 kDa and the accession number is AAH13294.1.
TMPH-01363	Galectin-8/LGALS8 Protein, Human, Recombinant (GST) Po66 carbohydrate-binding protein,LGALS8,Prostate c...	Human	E. coli
	Galectin-8/LGALS8 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 62.8 kDa and the accession number is O00214.
TMPJ-00654	LGALS8 Protein, Human, Recombinant Prostate Carcinoma Tumor Antigen 1,Po66-CBP,Galecti...	Human	E. coli
	The Galectin family of proteins, with specificity for Nacetyllactosaminecontaining glycoproteins, consists of beta-galactoside binding lectins containing homologous carbohydrate recognition domains (CRDs). They also possess hemagglutination activity, which is attributable to their bivalent carbohydrate binding properties. Galectins are active both intracellularly and extracellularly. Although they are localized primarily in the cytoplasm and lack a classical signal peptide, galectins can also be...
TMPY-06960	PSMA Protein, Human, Recombinant (His & Avi), Biotinylated GCPII,FGCP,folate hydrolase (prostate-specific memb...	Human	HEK293 Cells
	PSMA Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 82.72 kDa and the accession number is NP_004467.1.
TMPY-05269	PSMA Protein, Human, Recombinant (His), Biotinylated PSM,GCP2,folate hydrolase (prostate-specific membra...	Human	HEK293 Cells
	PSMA Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 81.7 kDa and the accession number is Q04609-1.
TMPH-01103	Claudin-3 Protein-VLP, Human, Recombinant (His) Clostridium perfringens enterotoxin receptor 2,C7orf1,hRVP1,...	Human	HEK293 Cells
	Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Claudin-3 Protein-VLP, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-10xHis tag. The predicted molecular weight is 24.7 kDa and the accession number is O15551.
TMPH-01102	Claudin-3 Protein, Human, Recombinant (B2M & His) Rat ventral prostate.1 protein homolog,hRVP1,CPE-re...	Human	E. coli
	Claudin-3 Protein, Human, Recombinant (B2M & His) is expressed in E. coli.
TMPH-01101	Claudin-3 Protein, Human, Recombinant (Cell-Free, His) Clostridium perfringens enterotoxin receptor 2,CPE-receptor ...	Human	E. coli
	Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. Claudin-3 Protein, Human, Recombinant (Cell-Free, His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 26.1 kDa and the accession number is O15551.
TMPJ-00278	Clusterin Protein, Human, Recombinant (hFc & His) CLU,NA1/NA2,TRPM-2,40,Apo-J,Clusterin,Complement Cytolysis I...	Human	HEK293 Cells
	Clusterin Protein, Human, Recombinant (hFc & His) is expressed in HEK293 mammalian cells with C-Fc-6xHis tag. The predicted molecular weight is (33-45) and (60-85) KDa and the accession number is P10909.
TMPJ-00279	Clusterin Protein, Human, Recombinant (His) Clusterin,Ku70-Binding Protein 1,Apo-J,Testosterone-Represse...	Human	HEK293 Cells
	Clusterin Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 28-40 KDa and the accession number is P10909.
TMPY-02258	Kallikrein 3/KLK3 Protein, Human, Recombinant (His) APS,KLK2A1,PSA,kallikrein related peptidase 3,Hk3	Human	HEK293 Cells
	KLK3 (Kallikrein Related Peptidase 3) is a Protein Coding gene. The gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. It encodes a single-chain glycoprotein, a protease that is synthesized in the epithelial cells of the prostate gland and is present in seminal plasma. KLK3, also known as Prostate Specific Antigen (PSA), kallikrein-related peptidase 3, Gamma-seminoprotein, is a secreted protein of the glandular kallikrein subfamily of serine proteases....
TMPY-04830	GAS6 Protein, Mouse, Recombinant (His) growth arrest-specific 6,Gas-6	Mouse	HEK293 Cells
	The growth arrest-specific 6 gene (GAS6) is a member of the family of plasma vitamin K-dependent proteins, which are able to bind to phospholipids using an N-terminal gamma-carboxyglutamic acid domain. GAS6 is a vitamin K-dependent protein, plays a role in the survival, proliferation, migration, differentiation, adhesion, and apoptosis of cells. The growth arrest-specific 6 (GAS6) has been implicated in systemic inflammation and coagulation. Growth arrest-specific 6 (GAS6), plays a role in tumor...
TMPY-03274	CXCL11 Protein, Human, Recombinant SCYB9B,I-TAC,chemokine (C-X-C motif) ligand 11,H174,SCYB11,I...	Human	E. coli
	I-TAC, also known as CXCL11, is a small cytokine belonging to the CXC chemokine family. It is highly expressed in peripheral blood leukocytes, pancreas and liver, with moderate levels in thymus, spleen and lung and low expression levels were in small intestine, placenta and prostate. The I-TAC chemokine elicits its effects on its target cells by interacting with the cell surface chemokine receptor CXCR3, with a higher affinity than do the other ligands for this receptor, CXCL9 and CXCL10. I-TAC ...
TMPJ-00662	RANKL/TNFSF11/CD254 Protein, Human, Recombinant (E. coli) Receptor activator of nuclear factor kappa-B ligand,Receptor...	Human	E. coli
	CD254, also known as RANKL, TNFSF11, TRANCE, OPGL and ODF, is a type II membrane protein of the tumor necrosis factor (TNF) superfamily, and affects the immune system and control bone regeneration and remodeling. RANKL is the ligand of nuclear factor (NF)-κB (RANK). When RANKL binds to RANK, it will undergo trimerization and then bind to an adaptor molecule TNF receptor-associated factor 6 (TRAF6). This results in the activation of several downstream signaling cascades, including the NFκB, mitog...
TMPY-05510	BDNF Protein, Mouse, Recombinant (His) brain-derived neurotrophic factor	Mouse	HEK293 Cells
	BDNF is a member of thenerve growth factorfamily. It is highly expressed in hippocampus, amygdala, cerebral cortex and cerebellum. It also can be detected in heart, lung, skeletal muscle, testis, prostate and placenta. BDNF is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. During development, BDNF promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. It participates in axonal growth,...
TMPJ-00042	TSLP Protein, Human, Recombinant TSLP,Thymic stromal lymphopoietin	Human	E. coli
	Thymic stromal lymphopoietin (TSLP) is a novel member of the hemopoietic cytokine family that promotes the development of B cells and shares overlapping activity with IL-7. The human TSLP protein comprises a 28 amino acids (aa) signal sequence and 131 aa mature region. Human TSLP has two isoforms lfTSLP and sfTSLP produced by alternative splicing . lfTSLP is expressed in a number of tissues including heart, liver and prostate, and sfTSLP (63aa) is predominantly expressed in keratinocytes of oral...
TMPK-00370	PSMA Protein, Human, Recombinant (hFc) NAALAdase,FOLH1,FOLHNAALADase I,FGCP,mGCP,PSMAFGCP,NAALADase...	Human	HEK293 Cells
	Prostate-specific membrane antigen (PSMA) is an enzyme that in humans is encoded by the FOLH1 (folate hydrolase 1) gene, also known as Glutamate carboxypeptidase II (GCPII). Human PSMA is highly expressed in the prostate, roughly a hundred times greater than in most other tissues. In some prostate cancers, PSMA is the second-most upregulated gene product, with an 8- to 12-fold increase over levels in noncancerous prostate cells. PSMA Protein, Human, Recombinant (hFc) is expressed in HEK293 mamma...
TMPK-00522	PSMA Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated PSMAFGCP,PSM,NAALAdase,NAALADase I,FOLHNAALADase I,GCPIImGCP...	Cynomolgus	HEK293 Cells
	Prostate-specific membrane antigen (PSMA) is an enzyme that in humans is encoded by the FOLH1 (folate hydrolase 1) gene, also known as Glutamate carboxypeptidase II (GCPII). Human PSMA is highly expressed in the prostate, roughly a hundred times greater than in most other tissues. In some prostate cancers, PSMA is the second-most upregulated gene product, with an 8- to 12-fold increase over levels in noncancerous prostate cells. PSMA Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His...
TMPK-00371	PSMA Protein (Primary Amine Labeling), Mouse, Recombinant (His), Biotinylated NAALADase I,FOLH1,GCPIImGCP,FGCP,GCP2,PSM,mGCP,NAALAdase,FOL...	Mouse	HEK293 Cells
	Prostate-specific membrane antigen (PSMA) is an enzyme that in humans is encoded by the FOLH1 (folate hydrolase 1) gene, also known as Glutamate carboxypeptidase II (GCPII). Human PSMA is highly expressed in the prostate, roughly a hundred times greater than in most other tissues. In some prostate cancers, PSMA is the second-most upregulated gene product, with an 8- to 12-fold increase over levels in noncancerous prostate cells. PSMA Protein (Primary Amine Labeling), Mouse, Recombinant (His), Bi...
TMPK-00521	PSMA Protein, Cynomolgus, Recombinant (His) PSMA,FOLHNAALADase I,FGCP,GCPII,PSMAFGCP,NAALADase I,PSM,NAA...	Cynomolgus	HEK293 Cells
	Prostate-specific membrane antigen (PSMA) is an enzyme that in humans is encoded by the FOLH1 (folate hydrolase 1) gene, also known as Glutamate carboxypeptidase II (GCPII). Human PSMA is highly expressed in the prostate, roughly a hundred times greater than in most other tissues. In some prostate cancers, PSMA is the second-most upregulated gene product, with an 8- to 12-fold increase over levels in noncancerous prostate cells. PSMA Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 ...
TMPY-04764	PCK2 Protein, Human, Recombinant (His & GST) PEPCK-M,PEPCK2,PEPCK,phosphoenolpyruvate carboxykinase 2 (mi...	Human	Baculovirus Insect Cells
	PCK2 promotes tumor initiation by lowering acetyl-CoA level through reducing the mitochondrial tricarboxylic acid (TCA) cycle. The levels of phosphoenolpyruvate carboxykinase isoform 2 (PCK2) are critical for the metabolic switch and the maintenance of TICs in prostate cancer. PCK2 is a potential therapeutic target for aggressive prostate tumors.
TMPK-00703	IL-17Rc Protein, Human, Recombinant (hFc) IL-17 receptor C,IL-17RC,ZcytoR14,IL-17RL,IL17Rhom	Human	HEK293 Cells
	IL-17RC (interleukin-17 receptor-like) gene codes for a transmembrane protein, the full length of which inhibits apoptosis in prostate cancer cells. IL-17RC gene transcribes over a dozen different splice variants of mRNA. IL-17RC protein isoforms are differentially expressed in prostatic cells and cancer tissues and may play a negative or positive role in the initiation and progression of prostate cancer.
TMPK-00906	PSCA Protein, Mouse, Recombinant (hFc) UNQ206,PSCA,PRO232	Mouse	HEK293 Cells
	Gastric cancer is a deadly malignancy and is a prognostically unfavorable entity with restricted therapeutic strategies available. Prostate stem cell antigen (PSCA) is a glycosylphosphatidylinositol (GPI)-anchored cell surface protein widely expressed in bladder, prostate, and pancreatic cancers. Existing studies have thoroughly recognized the availability of utilizing anti-PSCA CAR-T cells in the treatment of metastatic prostate cancer and non-small-cell lung cancer. PSCA Protein, Mouse, Recomb...
TMPK-00728	PSCA Protein, Human, Recombinant (hFc) UNQ206,PRO232,PSCA	Human	HEK293 Cells
	Gastric cancer is a deadly malignancy and is a prognostically unfavorable entity with restricted therapeutic strategies available. Prostate stem cell antigen (PSCA) is a glycosylphosphatidylinositol (GPI)-anchored cell surface protein widely expressed in bladder, prostate, and pancreatic cancers. Existing studies have thoroughly recognized the availability of utilizing anti-PSCA CAR-T cells in the treatment of metastatic prostate cancer and non-small-cell lung cancer. PSCA Protein, Human, Recomb...
TMPK-01387	EPhA3 Protein, Canine, Recombinant (His) HEK4,TYRO4,ETK1,EPHA3,HEK,ETK,EK4	Canine	HEK293 Cells
	Erythropoietin‑producing hepatocellular carcinoma cell surface type‑A receptor 3 (EPHA3) has been found to promote the proliferation and survival of prostate cancer (PCa) cell lines and prostate tumor development in nude mice. The interaction of AR and SP1 contributes to regulate EPHA3 expression, and the SP1 binding sites (‑295~‑261) in the EPHA3 core promoter region is crucial to the regulation of EPHA3 expression in response to androgen hormone stimuli.
TMPJ-01288	KLF6 Protein, Human, Recombinant CPBP,GC-Rich Sites-Binding Factor GBF,Suppressor of Tumorige...	Human	E. coli
	Krueppel-Like Factor 6 (KLF6) belongs to the krueppel C2H2-type zinc-finger protein family. KLF6 contains three C2H2-type zinc fingers and localizes in the nucleus. KLF6 expression is highest in the placenta followed by spleen, thymus, prostate, testis, small intestinem and colon. However, it is weakly expressed in the pancreas, lung, liver, heart, and skeletal muscle. KLF6 functions as a transcriptional activator and could play a role in B-cell growth and development. Defects in KLF6 will resul...
TMPJ-00891	Kallikrein 2/KLK2 Protein, Human, Recombinant (His) hGK-1,Kallikrein-2,Tissue Kallikrein-2,KLK2,Glandular Kallik...	Human	HEK293 Cells
	Kallikrein-2 (KLK2) is a secreted serine protease that belongs to the peptidase S1 family of Kallikrein subfamily. KLK2 contains 1 peptidase S1 domain. It is highly expressed in the human prostate gland. KLK2 can cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin, but Preferential cleavages of Arg-\|-Xaa bonds in small molecule substrates. It also highly selective action to release kallidin (lysyl-bradykinin) from kininogen involves hydrolysis of Met-\|-Xaa or Leu-\|-Xaa. KLK2 ...
TMPJ-00514	ACPP Protein, Human, Recombinant (His) Ecto-5'-Nucleotidase,TMPase,5'-Nucleotidase,Thiamine Monopho...	Human	HEK293 Cells
	Prostatic Acid Phosphatase (PAP) belongs to the histidine acid phosphatase family. PAP can catalyze the hydrolysis of member of phosphate monoestyers, including phosphorylated protein. PAP can high expression in metastasized prostate cancer, moderately expression level in bone diseases, blood cell disease, and the concentration of PAP is used to monitor and assess the proession of prostate cancer. The optimum PH of PAP is from 4 to 6; its activity can be inhibited by L(+)-tartrate.
TMPJ-00686	B4GALT3 Protein, Human, Recombinant (His) β-1,4-galactosyltransferase 3,Beta-1,B4GALT3	Human	HEK293 Cells
	Beta-1,4-galactosyltransferase 3 (B4GALT3) belongs to the glycosyltransferase 7 family. It is responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids. It is highest expression in placenta, prostate, testis, ovary, intestine and muscle, and in fetal brain.
TMPJ-00733	SPINK1 Protein, Human, Recombinant (His) PSTI,Pancreatic Secretory Trypsin Inhibitor,TATI,Serine Prot...	Human	HEK293 Cells
	Serine Protease Inhibitor Kazal-Type 1 (SPINK1) is a trypsin inhibitor that prevent the trypsin-catalyzed premature activation of zymogens within the pancreas. Defects in SPINK1 are a cause of pancreatitis (PCTT). A disease characterized by the presence of calculi in pancreatic ducts. It causes severe abdominal pain attacks. Defects in SPINK1 are the cause of susceptibility to tropical calcific pancreatitis (TCP). Recombinant SPINK1 protein (rSPINK1) stimulated cell proliferation in benign RWPE ...
TMPY-01771	Latexin Protein, Mouse, Recombinant (His) latexin	Mouse	E. coli
	Latexin, also known as endogenous carboxypeptidase inhibitor, tissue carboxypeptidase inhibitor, TCI, ECI, and LXN, is a cytoplasm protein that belongs to the protease inhibitor I47 (latexin) family. It is highly expressed in the heart, prostate, ovary, kidney, pancreas, and colon. Latexin / LXN is the only known endogenous specific inhibitor of zinc-dependent metallocarboxypeptidases (MCPs) present in mammalians so far. Latexin is originally identified as a molecular marker for the regional spe...
TMPJ-01156	PHLDA2 Protein, Human, Recombinant (His) Beckwith-Wiedemann Syndrome Chromosomal Region 1 Candidate G...	Human	E. coli
	Pleckstrin Homology-Like Domain Family A Member 2 (PHLDA2) is a peripheral membrane protein that belongs to the PHLDA2 family. PHLDA2 is expressed in the placenta and adult prostate gland. In the placenta, it is present in all cells of the villous cytotrophoblast. PHLDA2 plays a role in regulating placenta growth. PHLDA2 may act via its PH domain that competes with other PH domain-containing proteins, thereby preventing their binding to membrane lipids.
TMPK-01375	PRLR Protein, Canine, Recombinant (hFc) PRL-R,Prolactin R,MFAB,HPRL	Canine	HEK293 Cells
	Prolactin receptor (PRLR) is highly expressed in a subset of human breast cancer and prostate cancer, which makes it a potential target for cancer treatment. In clinical trials, the blockade of PRLR was shown to be safe but with poor efficacy. It is therefore urgent to develop new therapies against PRLR target. Bispecific antibodies (BsAbs) could guide immune cells toward tumor cells, and produced remarkable effects in some cancers. PRLR Protein, Canine, Recombinant (hFc) is expressed in HEK293 ...
TMPY-03867	CBR3 Protein, Human, Recombinant (His) SDR21C2,carbonyl reductase 3,hCBR3,HEL-S-25	Human	E. coli
	CBR3, also known as hCBR3, belongs to the short-chain dehydrogenases/reductases (SDR) family. CBR3 is expressed in ovary, pancreas, intestine, colon, kidney, brain, thymus, lung, heart, liver, spleen, leukocyte, prostate and testis. It is a monomeric NADPH-dependent oxidoreductase and is closely linked to another carbonyl reductase gene – CBR1. CBR3 catalyzes the reduction of a large number of biologically and pharmacologically active carbonyl compounds to their corresponding alcohols. It has lo...
TMPJ-00114	EFNA3 Protein, Mouse, Recombinant (hFc) EFL2,LERK-3,EFNA3,Ephrin-A3,EHK1-L,EPLG3,EFL-2,EHK1 Ligand,L...	Mouse	HEK293 Cells
	Ephrins-A3 belongs the Ephrins ligand family which involved in a variety of biological processes, especially in the nervous system and in erythropoiesis. It is shown that Ephrin-A3 is expressed in brain, skeletal muscle, spleen, thymus, prostate, testis, ovary, small intestine, and peripheral blood leukocytes. Ephrin-A3 has a GPI anchor following the extracellular sequence and a signal sequence of 22 amino acids. Ephrin-A3 can bind EphA2, EphA3, EphA4, EphA5, EphA6, EphA7, EphA8 and EphB1. Futhe...
TMPK-00547	PRLR Protein, Cynomolgus, Recombinant (His) Prolactin R,HPRL,MFAB,PRL-R	Cynomolgus	HEK293 Cells
	Prolactin receptor (PRLR) is highly expressed in a subset of human breast cancer and prostate cancer, which makes it a potential target for cancer treatment. In clinical trials, the blockade of PRLR was shown to be safe but with poor efficacy. It is therefore urgent to develop new therapies against PRLR target. Bispecific antibodies (BsAbs) could guide immune cells toward tumor cells, and produced remarkable effects in some cancers. PRLR Protein, Cynomolgus, Recombinant (His) is expressed in HEK...
TMPU-00004	STAT5A Protein, Human, Recombinant (His) MGF,Signal transducer and activator of transcription 5A	Human	E. coli
	Signal transducer and activator of transcription 5A is a protein that in humans is encoded by the STAT5A gene. Many studies have indicated a key role of STAT5a in leukemia, breast, colon, head and neck, and prostate cancer. Until recently, the unique characteristics and function of STAT5a in these cancers have not been delineated from STAT5b, and more research into their differential behavior is warranted. Because of its integral role in immune cell development, STAT5a may contribute to tumor de...
TMPH-02236	TMPRSS2 Protein, Human, Recombinant (E. coli, His) Transmembrane protease serine 2,TMPRSS2,Serine protease 10	Human	E. coli
	Plasma membrane-anchored serine protease that participates in proteolytic cascades of relevance for the normal physiologic function of the prostate. Androgen-induced TMPRSS2 activates several substrates that include pro-hepatocyte growth factor/HGF, the protease activated receptor-2/F2RL1 or matriptase/ST14 leading to extracellular matrix disruption and metastasis of prostate cancer cells. In addition, activates trigeminal neurons and contribute to both spontaneous pain and mechanical allodynia....
TMPH-02237	TMPRSS2 Protein, Human, Recombinant (His & Myc) Serine protease 10,Transmembrane protease serine 2,TMPRSS2	Human	HEK293 Cells
	Plasma membrane-anchored serine protease that participates in proteolytic cascades of relevance for the normal physiologic function of the prostate. Androgen-induced TMPRSS2 activates several substrates that include pro-hepatocyte growth factor/HGF, the protease activated receptor-2/F2RL1 or matriptase/ST14 leading to extracellular matrix disruption and metastasis of prostate cancer cells. In addition, activates trigeminal neurons and contribute to both spontaneous pain and mechanical allodynia....
TMPY-04025	CEP57 Protein, Human, Recombinant (GST) MVA2,PIG8,TSP57,centrosomal protein 57kDa	Human	E. coli
	CEP57 is a centrosomal protein and is involved in nucleating and stabilizing microtubules. CEP57 was initially identified as a regulator of centriole overduplication in an RNA interference screen. There is a link between altered microenvironmental signaling cues such as FGF-2 overexpression and mitotic instability and provide a rationale for the therapeutic targeting of the FGF-2/FGFR1/CEP57 axis in prostate cancer. CEP57 is involved in intracellular transport processes, and its overexpression c...
TMPJ-00482	SEMG1 Protein, Human, Recombinant (His) SGI,SEMG,Semenogelin-1,Seminal Basic Protein,Alpha-Inhibin-3...	Human	HEK293 Cells
	Semenogelin-1 (SEMG1) is the predominant protein in semen; it is a secretory protein involved in the formation of a gel matrix entrapping the accessory gland secretions and ejaculated spermatozoa. The prostate-specific antigen (PSA) protease processes SEMG1 into smaller peptides, each possibly having a separate function. In the proteolysis process, Alpha-inhibin-92 and alpha-inhibin-31 are produced; they inhibit the secretion of pituitary follicle-stimulating hormone. At the same time, it breaks...
TMPJ-01058	ARG2 Protein, Human, Recombinant (His) ARG2,Kidney-type arginase,Type II arginase,Arginase-2, mitoc...	Human	E. coli
	Arginase-2 (ARG2) is a member of the arginase family. Arginase is a manganese-containing enzyme which catalyzes the hydrolysis of arginine to ornithine and urea. ARG2 is highly expressed in kidney and prostate, not founded in the liver, heart and pancreas. ARG2 has been implicated in the regulation of the arginine/ornithine concentrations in the cell. ARG2 may take part in the regulation of extra-urea cycle arginine metabolism and in down-regulation of nitric oxide synthesis. The extrahepatic ar...
TMPJ-01293	SEMA3C Protein, Human, Recombinant (His) Semaphorin-E,SEMA3C,SEMAE,Semaphorin-3C,Sema E	Human	HEK293 Cells
	Semaphorin 3C is one of six Class 3 secreted semaphorins, which are potent chemorepellents, that play a role in axon and/or vascular guidance during development can be up-regulated in the process of tumor progression. Semaphorin 3C consists of a 20 amino acids signal sequence, a N-terminal Sema domain, a cysteine knot, a furine-type cleavage site, an Ig-like domain, and a C-terminal basic domain. Semaphorin 3C expressed highly in the heart, colon, skeletal muscle, small intestine, testis, ovary ...
TMPJ-00349	RANK/TNFRSF11A Protein, Human, Recombinant (aa 30-212, His) CD265 antigen,FEO,TRANCER,ODFR,ODFROSTS,TRANCE R,TNFRSF11A,O...	Human	HEK293 Cells
	Receptor Activator of Nuclear Factor κ B (RANK), also known as CD265, TRANCE Receptor or TNFRSF11A, is member of the tumor necrosis factor receptor (TNFR) molecular superfamily. RANK is the receptor for RANK-Ligand (RANKL) and part of the RANK/RANKL/OPG signaling pathway that regulates osteoclast differentiation and activation. It plays a vital role in bone remodeling and repair, immune cell function, lymph node development, thermal regulation, and mammary gland development. RANK is constitutive...
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重组蛋白

PSMA Protein, Human, Recombinant (His)

Cat.No: TMPY-00381

Species: Human

Expression System: HEK293 Cells

PSCA Protein, Mouse, Recombinant (His & Avi), Biotinylated

Cat.No: TMPY-06655

Species: Mouse

Expression System: HEK293 Cells

PSCA Protein, Mouse, Recombinant (His)

Cat.No: TMPY-06710

Species: Mouse

Expression System: HEK293 Cells

Prostatic Acid Phosphatase Protein, Human, Recombinant (His)

Cat.No: TMPY-02155

Species: Human

Expression System: HEK293 Cells

PSMA Protein, Mouse, Recombinant (His)

Cat.No: TMPY-01390

Species: Mouse

Expression System: HEK293 Cells

Prostatic Acid Phosphatase Protein, Mouse, Recombinant (His)

Cat.No: TMPY-02672

Species: Mouse

Expression System: HEK293 Cells

PARM-1 Protein, Human, Recombinant (His)

Cat.No: TMPY-00133

Species: Human

Expression System: HEK293 Cells

Galectin-8/LGALS8 Protein, Human, Recombinant (GST)

Cat.No: TMPH-01363

Species: Human

Expression System: E. coli

LGALS8 Protein, Human, Recombinant

Cat.No: TMPJ-00654

Species: Human

Expression System: E. coli

PSMA Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPY-06960

Species: Human

Expression System: HEK293 Cells

PSMA Protein, Human, Recombinant (His), Biotinylated

Cat.No: TMPY-05269

Species: Human

Expression System: HEK293 Cells

Claudin-3 Protein-VLP, Human, Recombinant (His)

Cat.No: TMPH-01103

Species: Human

Expression System: HEK293 Cells

Claudin-3 Protein, Human, Recombinant (B2M & His)

Cat.No: TMPH-01102

Species: Human

Expression System: E. coli

Claudin-3 Protein, Human, Recombinant (Cell-Free, His)

Cat.No: TMPH-01101

Species: Human

Expression System: E. coli

Clusterin Protein, Human, Recombinant (hFc & His)

Cat.No: TMPJ-00278

Species: Human

Expression System: HEK293 Cells

Clusterin Protein, Human, Recombinant (His)

Cat.No: TMPJ-00279

Species: Human

Expression System: HEK293 Cells

Kallikrein 3/KLK3 Protein, Human, Recombinant (His)

Cat.No: TMPY-02258

Species: Human

Expression System: HEK293 Cells

GAS6 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-04830

Species: Mouse

Expression System: HEK293 Cells

CXCL11 Protein, Human, Recombinant

Cat.No: TMPY-03274

Species: Human

Expression System: E. coli

RANKL/TNFSF11/CD254 Protein, Human, Recombinant (E. coli)

Cat.No: TMPJ-00662

Species: Human

Expression System: E. coli

BDNF Protein, Mouse, Recombinant (His)

Cat.No: TMPY-05510

Species: Mouse

Expression System: HEK293 Cells

TSLP Protein, Human, Recombinant

Cat.No: TMPJ-00042

Species: Human

Expression System: E. coli

PSMA Protein, Human, Recombinant (hFc)

Cat.No: TMPK-00370

Species: Human

Expression System: HEK293 Cells

PSMA Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated

Cat.No: TMPK-00522

Species: Cynomolgus

Expression System: HEK293 Cells

PSMA Protein (Primary Amine Labeling), Mouse, Recombinant (His), Biotinylated

Cat.No: TMPK-00371

Species: Mouse

Expression System: HEK293 Cells

PSMA Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-00521

Species: Cynomolgus

Expression System: HEK293 Cells

PCK2 Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-04764

Species: Human

Expression System: Baculovirus Insect Cells

IL-17Rc Protein, Human, Recombinant (hFc)

Cat.No: TMPK-00703

Species: Human

Expression System: HEK293 Cells

PSCA Protein, Mouse, Recombinant (hFc)

Cat.No: TMPK-00906

Species: Mouse

Expression System: HEK293 Cells

PSCA Protein, Human, Recombinant (hFc)

Cat.No: TMPK-00728

Species: Human

Expression System: HEK293 Cells

EPhA3 Protein, Canine, Recombinant (His)

Cat.No: TMPK-01387

Species: Canine

Expression System: HEK293 Cells

KLF6 Protein, Human, Recombinant

Cat.No: TMPJ-01288

Species: Human

Expression System: E. coli

Kallikrein 2/KLK2 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00891

Species: Human

Expression System: HEK293 Cells

ACPP Protein, Human, Recombinant (His)

Cat.No: TMPJ-00514

Species: Human

Expression System: HEK293 Cells

B4GALT3 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00686

Species: Human

Expression System: HEK293 Cells

SPINK1 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00733

Species: Human

Expression System: HEK293 Cells

Latexin Protein, Mouse, Recombinant (His)

Cat.No: TMPY-01771

Species: Mouse

Expression System: E. coli

PHLDA2 Protein, Human, Recombinant (His)

Cat.No: TMPJ-01156

Species: Human

Expression System: E. coli

PRLR Protein, Canine, Recombinant (hFc)

Cat.No: TMPK-01375

Species: Canine

Expression System: HEK293 Cells

CBR3 Protein, Human, Recombinant (His)

Cat.No: TMPY-03867

Species: Human

Expression System: E. coli

EFNA3 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPJ-00114

Species: Mouse

Expression System: HEK293 Cells

PRLR Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-00547

Species: Cynomolgus

Expression System: HEK293 Cells

STAT5A Protein, Human, Recombinant (His)

Cat.No: TMPU-00004

Species: Human

Expression System: E. coli

TMPRSS2 Protein, Human, Recombinant (E. coli, His)

Cat.No: TMPH-02236

Species: Human

Expression System: E. coli

TMPRSS2 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-02237

Species: Human

Expression System: HEK293 Cells

CEP57 Protein, Human, Recombinant (GST)

Cat.No: TMPY-04025

Species: Human

Expression System: E. coli

SEMG1 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00482

Species: Human

Expression System: HEK293 Cells

ARG2 Protein, Human, Recombinant (His)

Cat.No: TMPJ-01058

Species: Human

Expression System: E. coli

SEMA3C Protein, Human, Recombinant (His)

Cat.No: TMPJ-01293

Species: Human

Expression System: HEK293 Cells

RANK/TNFRSF11A Protein, Human, Recombinant (aa 30-212, His)

Cat.No: TMPJ-00349

Species: Human

Expression System: HEK293 Cells

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Cat. No.	Product Name	Target	Signaling Pathways
T69758	Flutamide-d7
	Flutamide-d7 is intended for use as an internal standard for the quantification of flutamide by GC- or LC-MS. Flutamide is an androgen receptor antagonist and prodrug form of 2-hydroxy flutamide. Flutamide is converted to 2-hydroxy flutamide by the cytochrome P450 (CYP) isoform CYP1A2 in human liver microsomes. It is cytotoxic to PC3 and LNCaP prostate cancer cells with IC50 values of 98.8 and 81.8 µM, respectively. Flutamide (50 mg/kg per day) reduces tumor growth in a PC-82 mouse xenograft mo...
T11208	Enzalutamide-d3 MDV3100 D3	Others	Others
	Enzalutamide D3 is a deuterium labeled Enzalutamide . Enzalutamide is an androgen receptor (AR) antagonist with an IC50 of 36 nM in LNCaP prostate cells.
TMIJ-0268	Relugolix-d6
	Relugolix-d6 是 Relugolix 的氘代化合物。Relugolix 的 CAS 号为 737789-87-6。Relugolix 是口服有活性的非肽性促性腺激素释放激素的拮抗剂。同 TAK-013 相比，它对人和猴子的受体具有高亲和力和强拮抗活性，它们的IC50值分别为0.33 nM和0.32 nM。它可用于研究性激素依赖性疾病，如子宫肌瘤、子宫内膜异位症、前列腺癌等。
T73246	EZH2-IN-7
	EZH2-IN-7 是一种有效的EZH2抑制剂。EZH2过表达或 SET 区突变 (Y641F、Y641N、A687V、A677G 点突变) 均导致H3K27me3异常升高，促进多种肿瘤的生长发育，如乳腺癌、前列腺癌、白血病等。EZH2-IN-7 具有研究癌症疾病的潜力。
TMIH-0089	Androstenedione-d7
	Androstenedione-d7 是 Androstenedione 的氘代化合物。Androstenedione 的 CAS 号为 560-62-3。9-hydroxy-4-androstene-3,17-dione 是一种类固醇激素，具有抗肿瘤活性，可以抑制多种癌症细胞的生长，包括乳腺癌、前列腺癌和肺癌细胞。
TMIJ-0337	(24Rac)-Campesterol-d7
	(24Rac)-Campesterol-d7 是 (24Rac)-Campesterol 的氘代化合物。(24Rac)-Campesterol 的 CAS 号为 474-62-4。Campesterol是一种植物甾醇，具有降胆固醇和抗癌的活性。
TMID-0097	Ethyl-d5-malonic Acid
	Ethyl-d5-malonic Acid 是 Ethyl-malonic Acid 的氘代化合物。Ethyl-malonic Acid 的 CAS 号为 601-75-2。Ethylmalonic acid 是潜在有毒物质，非致癌性，与神经性厌食和甲氧基脱羧酶缺乏症有关。
T70882	Orlistat-d3
	Orlistat-d3 is intended for use as an internal standard for the quantification of orlistat by GC- or LC-MS. Orlistat is a digestive lipase inhibitor. It inhibits diacylglycerol lipase α (DAGLα), DAGLβ, α/β-hydrolase domain-containing protein 12 (ABHD12), ABHD16A, and platelet-activating factor acetylhydrolase (PAF-AH; IC50s = 0.06, 0.1, 0.08, 0.03, and 0.05 µM, respectively), as well as pancreatic lipase and hormone-sensitive lipase (IC50s = 0.65 and 2.1 µg/ml, respectively) but does not inhibit...
TMIH-0521	Silibinin-d3
	Silibinin-d3 是 Silibinin 的氘代化合物。Silibinin 的 CAS 号为 22888-70-6。Silibinin 是水飞蓟的主要活性成分，具有抗癌和化疗预防作用，能抑制细胞增殖和迁移。

同位素标记化合物

Cat.No: T69758

Enzalutamide-d3

Cat.No: T11208

Synonym: MDV3100 D3

Target: Others

Cat.No: TMIJ-0268

Cat.No: T73246

Androstenedione-d7

Cat.No: TMIH-0089

(24Rac)-Campesterol-d7

Cat.No: TMIJ-0337

Ethyl-d5-malonic Acid

Cat.No: TMID-0097

Cat.No: T70882

Cat.No: TMIH-0521

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