|
TMPH-01410
|
GPR84 Protein, Human, Recombinant (hFc)
G-protein coupled receptor 84,GPR84,Inflammation-re...
|
Human
|
P. pastoris (Yeast)
|
|
Receptor for medium-chain free fatty acid (FFA) with carbon chain lengths of C9 to C14. Capric acid (C10:0), undecanoic acid (C11:0) and lauric acid (C12:0) are the most potent agonists. Not activated by short-chain and long-chain saturated and unsaturated FFAs. Activation by medium-chain free fatty acid is coupled to a pertussis toxin sensitive G(i/o) protein pathway. May have important roles in processes from fatty acid metabolism to regulation of the immune system. GPR84 Protein, Human, Recom... |
|
TMPK-01074
|
CD163 Protein, Human, Recombinant (His & Avi)
CD163,HbSR,RM3/1,MM130,CD163 molecule,GHI/61,sCD163,SCARI1,M...
|
Human
|
HEK293 Cells
|
|
The hemoglobin (Hb) scavenger receptor, CD163, is a macrophage-specific protein and the upregulated expression of this receptor is one of the major changes in the macrophage switch to alternative activated phenotypes in inflammation. Accordingly, a high CD163 expression in macrophages is a characteristic of tissues responding to inflammation. CD163 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 111.4 kDa and th... |
|
TMPK-01246
|
GDF-15 Protein, Mouse, Recombinant (His)
MIC1,Placental TGF-beta,Placental TGF-β,PTGF-beta,PTGFBPTGF-...
|
Mouse
|
E. coli
|
|
Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and that GDF15 was necessary for surviving both bacterial and viral infections, as well as sepsis. The protective effects of GDF15 were largely independent of pathogen control or the magnitude of inflammatory response, suggesting a role in disease tolerance. GDF-15 Protein, Mouse, Rec... |
|
TMPK-00831
|
Galectin-3 Protein, Mouse, Recombinant (His)
Galectin3,LGALS2,AGE-R3,L31,LGALS3,Mac-2,GAL3,L29,Gal-3,GALI...
|
Mouse
|
HEK293 Cells
|
|
Galectin-3 (Gal-3) is a 30 kDa β-galactose, highly conserved and widely distributed intracellularly and extracellularly. Gal-3 has been demonstrated in recent years to be a novel inflammatory factor participating in the process of intravascular inflammation, lipid endocytosis, macrophage activation, cellular proliferation, monocyte chemotaxis, and cell adhesion. |
|
TMPY-01736
|
COX-2 Protein, Human, Recombinant (His)
GRIPGHS,PHS-2,hCox-2,COX-2,PGHS-2,prostaglandin-endoperoxide...
|
Human
|
Baculovirus Insect Cells
|
|
PTGS2, also known as COX-2, is s component of Prostaglandin-endoperoxide synthase (PTGS). PTGS, also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. PTGS2 is overexpressed in many cancers. The overexpression of PTGS2 along with increased angiogenesis and GLUT-1 expression ... |
|
TMPY-02869
|
MMP-12 Protein, Human, Recombinant (catalytic domain)
HME,ME,MMP-12,MME,matrix metallopeptidase 12
|
Human
|
E. coli
|
|
Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that degrade components of the extracellular matrix (ECM) and play essential roles in various physiological processes such as morphogenesis, differentiation, angiogenesis, and tissue remodeling, as well as pathological processes including inflammation, arthritis, cardiovascular diseases, pulmonary diseases, and tumor invasion. Macrophage Metalloelastase, also known as Matrix metalloproteinase-12, Macrophage elastase, ... |
|
TMPJ-00779
|
TNF alpha Protein, Rabbit, Recombinant
TNF-a,Tumor Necrosis Factor,TNF-α,TNF α,Cachectin,肿瘤坏死因子,Tum...
|
Rabbit
|
E. coli
|
|
Tumor necrosis factor alpha (TNFα) is the prototypic ligand of the TNF superfamily. TNFα forms a homotrimer and functions by activating two types of receptors TNF-R1 (TNF receptor type 1,p55R) and TNF-R2 (TNF receptor type 2,p75R). TNFα is a pleiotropic cytokine that is capable to promote inflammation, to induce apoptotic cell death, and to inhibit tumorigenesis and viral replication. TNFα is a potent lymphoid factor that exerts cytotoxic effects on a wide range of tumor cells and certain other ... |
|
TMPK-00114
|
C-Reactive Protein /CRP Protein, Human, Recombinant (His)
C-reactive protein,MGC88244,PTX1MGC149895,CRP,pentraxin 1,PT...
|
Human
|
HEK293 Cells
|
|
C-reactive protein (CRP) is a polypeptide molecule belonging to the family of pentraxins. CRP is synthesized primarily by the liver in response to certain pro-inflammatory cytokines. It plays an important role in innate immunity, opsonization by its properties, complement activation and immunoglobulins receptor binding. CRP is a protein of the acute systemic inflammation and is, therefore, a prime marker of inflammation.The CRP is quantified by immunonephelometry or immunoturbidimetry. C-Reactiv... |
|
TMPY-00672
|
Azurocidin/CAP37 Protein, Human, Recombinant (His)
AZU,NAZC,azurocidin 1,hHBP,AZAMP,HUMAZUR,CAP37,HBP,AZU1
|
Human
|
HEK293 Cells
|
|
Azurocidin (AZU1), also known as heparin-binding protein (HBP) or cationic antimicrobial protein 37 (CAP37), is an azurophil granule antibiotic protein, with monocyte chemotactic and antibacterial activity. The Azurophil granules, specialized lysosomes of the neutrophil, contain at least 10 proteins implicated in the killing of microorganisms. Azurocidin is a member of the serine protease family that includes Cathepsin G, neutrophil elastase (NE), and proteinase 3 (PR3), however, Azurocidin is n... |
|
TMPJ-01172
|
IL-17 Protein, Mouse, Recombinant (His)
CTLA8,IL-17,IL-17A,Interleukin-17A,CTLA-8,Cytotoxic T-Lympho...
|
Mouse
|
HEK293 Cells
|
|
Interleukin-17 is a potent pro-inflammatory cytokine produced by activated memory T cells. There are at least six members of the IL-17 family in humans and in mice. Mature mouse IL-17A shares 61% and 89% amino acid sequence identity with human and rat IL-17A, respectively. As IL-17 shares properties with IL-1 and TNF-alpha, it may induce joint inflammation and bone and cartilage destruction. This cytokine is found in synovial fluids of patients with rheumatoid arthritis, and produced by rheumato... |
|
TMPJ-01467
|
Oncostatin M/OSM Protein, Human, Recombinant (E. coli, His)
Oncostatin-M,OSM
|
Human
|
E. coli
|
|
Oncostatin M (OSM) is a glycoprotein belonging to the interleukin-6 family of cytokines that includes leukemia-inhibitory factor, granulocyte colony-stimulating factor, and interleukin 6. OSM encodes a growth regulator, which Inhibits the proliferation of a number of tumor cell lines. It stimulates proliferation of AIDS-KS cells. OSM regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. OSM is considered as a pleiotropic cytokine that initiates its biological ac... |
|
TMPJ-01466
|
Osteoprotegerin Protein, Human, Recombinant (aa 22-401, His)
OPG,Tumor Necrosis Factor Receptor Superfamily Member 11B,OC...
|
Human
|
HEK293 Cells
|
|
TNFRSF11B is a secreted protein, containing 2 death domains and 4 TNFR-Cys repeats. TNFRSF11B is a decoy receptor for the receptor activator of nuclear factor kappa B ligand (RANKL). By binding RANKL, TNFRSF11B inhibits nuclear kappa B (NF-κB) which is a central and rapid acting transcription factor for immune-related genes, and a key regulator of inflammation, innate immunity, and cell survival and differentiation. TNFRSF11B levels are influenced by voltage-dependent calcium channelsCav1.2. TNF... |
|
TMPY-00566
|
CCL18 Protein, Human, Recombinant (His)
PARC,CCL18,CKb7,DC-CK1,chemokine (C-C motif) ligand 18,MIP-4...
|
Human
|
P. pastoris (Yeast)
|
|
CCL18 is a chemotactic cytokine involved in the pathogenesis and progression of various disorders, including cancer. Proof showed high levels of CCL18 in the serum of epithelial ovarian carcinoma patients suggesting its potential as a circulating biomarker. CCL18 chemokine has an important role in chemokine-mediated tumor metastasis, and may serve as a potential predictor for poor survival outcomes for ovarian cancer. (CCL18) is predominantly secreted by M2-tumor associated macrophages (TAMs) a... |
|
TMPJ-00387
|
IL-4R alpha Protein, Mouse, Recombinant (hFc)
Soluble IL-4R-alpha,Interleukin-4 receptor subunit alpha,Sol...
|
Mouse
|
HEK293 Cells
|
|
Interleukin-4 receptor subunit alpha(IL-4RA), alos known as Soluble IL-4 receptor subunit alpha, belongs to the type I cytokine receptor family and type 4 subfamily. It expressed in both Th1 and Th2 cells. It functions as receptor for both interleukin 4 and interleukin 13 and couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and chemokine and mucus production at sites of allergic ... |
|
TMPY-04830
|
GAS6 Protein, Mouse, Recombinant (His)
growth arrest-specific 6,Gas-6
|
Mouse
|
HEK293 Cells
|
|
The growth arrest-specific 6 gene (GAS6) is a member of the family of plasma vitamin K-dependent proteins, which are able to bind to phospholipids using an N-terminal gamma-carboxyglutamic acid domain. GAS6 is a vitamin K-dependent protein, plays a role in the survival, proliferation, migration, differentiation, adhesion, and apoptosis of cells. The growth arrest-specific 6 (GAS6) has been implicated in systemic inflammation and coagulation. Growth arrest-specific 6 (GAS6), plays a role in tumor... |
|
TMPY-02660
|
Resistin Protein, Mouse, Recombinant (hFc)
resistin,Xcp4,ADSF,Fizz3,Rstn
|
Mouse
|
HEK293 Cells
|
|
Resistin is an adipocytokine, which has been studied for its role in insulin resistance and recently in inflammation. The RETN and CAP1 polymorphisms and gene expression may be potential biomarkers for breast cancer risk. Resistin (RETN), recently found to be relevant to inflammation and inflammatory disorders. |
|
TMPH-02266
|
TNFAIP6 Protein, Human, Recombinant (His & Myc)
TNFAIP6,Tumor necrosis factor-inducible gene 6 protein,Tumor...
|
Human
|
Baculovirus Insect Cells
|
|
Possibly involved in cell-cell and cell-matrix interactions during inflammation and tumorigenesis. |
|
TMPK-00983
|
CD163 Protein, Mouse, Recombinant (His)
GHI/61,CD163 molecule,sCD163,HbSR,MM130,SCARI1,M130,CD163,RM...
|
Mouse
|
HEK293 Cells
|
|
The hemoglobin (Hb) scavenger receptor, CD163, is a macrophage-specific protein and the upregulated expression of this receptor is one of the major changes in the macrophage switch to alternative activated phenotypes in inflammation. Accordingly, a high CD163 expression in macrophages is a characteristic of tissues responding to inflammation. CD163 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 109.53 kDa and the accessi... |
|
TMPH-02578
|
CHI3L4 Protein, Mouse, Recombinant (His)
Chil4,Secreted protein Ym2,Ym2,Chitinase-3-like protein 4,Ch...
|
Mouse
|
P. pastoris (Yeast)
|
|
Has low chemotactic activity for eosinophils. May play a role in inflammation and allergy. Has no chitinase activity. |
|
TMPK-01170
|
Hepcidin/HAMP Protein, Mouse, Recombinant (GST)
Hamp1,LEAP-1,PLTR,HFE2B,LEAP1,Hepc1,Hepc
|
Mouse
|
E. coli
|
|
Hepcidin, the main regulator of iron metabolism, is synthesized and released by hepatocytes in response to increased body iron concentration and inflammation. Deregulation of hepcidin expression is a common feature of genetic and acquired iron disorders: in Hereditary Hemochromatosis (HH) and iron-loading anemias low hepcidin causes iron overload, while in Iron Refractory Iron Deficiency Anemia (IRIDA) and anemia of inflammation (AI), high hepcidin levels induce iron-restricted erythropoiesis. |
|
TMPK-00104
|
HMGB1 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated
HMG3,HMG-1,HMGB1,SBP-1,HMG1
|
Human
|
HEK293 Cells
|
|
High-mobility group box 1 (HMGB1) is a ubiquitous nuclear protein that promotes inflammation when released extracellularly after cellular activation, stress, damage or death. HMGB1 operates as one of the most intriguing molecules in inflammatory disorders via recently elucidated signal and molecular transport mechanisms. Treatments based on antagonists specifically targeting extracellular HMGB1 have generated encouraging results in a wide number of experimental models of infectious and sterile i... |
|
TMPK-01075
|
CD163 Protein, Human, Recombinant (His & Avi), Biotinylated
HbSR,sCD163,M130,GHI/61,MM130,CD163 molecule,CD163,RM3/1,SCA...
|
Human
|
HEK293 Cells
|
|
The hemoglobin (Hb) scavenger receptor, CD163, is a macrophage-specific protein and the upregulated expression of this receptor is one of the major changes in the macrophage switch to alternative activated phenotypes in inflammation. Accordingly, a high CD163 expression in macrophages is a characteristic of tissues responding to inflammation. CD163 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 11... |
|
TMPK-01154
|
AMCase/CHIA Protein, Human, Recombinant (His)
YNL,AMCase,Chia1,CHIA,Acidic mammalian chitinase,EC 3.2.1.14...
|
Human
|
HEK293 Cells
|
|
Acidic mammalian chitinase (AMCase) and chitotriosidase (CHIT-1) are two active chitinases expressed in humans. The chitinase activity of AMCase was found to be causative in allergic inflammation and its expression was found to be induced by interleukin-13. CHIT1-1 is expressed by phagocytic cells and extremely high levels are seen in lysosomal storage diseases. Despite that AMCase expression in the inflammation is under investigation, little is known regarding its regulation during macrophages'... |
|
TMPY-04398
|
MST1 Protein, Human, Recombinant (His)
serine/threonine kinase 4,KRS2,MST1,TIIAC,YSK3
|
Human
|
Baculovirus Insect Cells
|
|
Dysregulation of MST1/STK4, a key kinase component of the Hippo-YAP pathway, is linked to the etiology of many cancers with poor prognosis. STK4/Hippo pathway may have important therapeutic implications for cancer. The tumor suppressor serine/threonine-protein kinase 4 (STK4) differentially regulates TLR3/4/9-mediated inflammatory responses in macrophages and thereby is protective against chronic inflammation-associated Hepatocellular carcinoma (HCC). STK4 has potential as a diagnostic biomarker... |
|
TMPK-01244
|
GDF-15 Protein, Mouse, Recombinant (hFc)
PTGFBPTGF-beta,PTGFB,PLAB,NAG-1,Placental TGF-β,RG-1,GDF15,G...
|
Mouse
|
HEK293 Cells
|
|
Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and that GDF15 was necessary for surviving both bacterial and viral infections, as well as sepsis. The protective effects of GDF15 were largely independent of pathogen control or the magnitude of inflammatory response, suggesting a role in disease tolerance. GDF-15 Protein, Mouse, Rec... |
|
TMPK-00212
|
CD300A Protein, Mouse, Recombinant (His)
MAIR-I,IGSF12,IRp60,Mcipr1,CLM8,NKRL,IRC1,CD300a,Pigr4,CLM-8...
|
Mouse
|
HEK293 Cells
|
|
CD300a is an inhibitory receptor for mast cells and eosinophils in allergic inflammation (AI); however, the spatiotemporal expression of CD300a and its potential roles in the resolution of AI are still to be determined.CD300a expression on peritoneal cells is regulated from inflammation to resolution. CD300a activation on mouse bone marrow-derived mast cells regulated ALX/FPR2 expression levels following IgE-mediated activation. CD300A Protein, Mouse, Recombinant (His) is expressed in HEK293 mam... |
|
TMPK-00561
|
CD300A Protein, Cynomolgus, Recombinant (His)
Mcipr1,IGSF12,IRp60,LMIR1,CD300a,MAIR-I,Pigr4,CLM-8,IRC1,NKR...
|
Cynomolgus
|
HEK293 Cells
|
|
CD300a is an inhibitory receptor for mast cells and eosinophils in allergic inflammation (AI); however, the spatiotemporal expression of CD300a and its potential roles in the resolution of AI are still to be determined.CD300a expression on peritoneal cells is regulated from inflammation to resolution. CD300a activation on mouse bone marrow-derived mast cells regulated ALX/FPR2 expression levels following IgE-mediated activation. CD300A Protein, Cynomolgus, Recombinant (His) is expressed in HEK29... |
|
TMPK-00560
|
CD300A Protein, Cynomolgus, Recombinant (Avi), Biotinylated
IGSF12,Mcipr1,NKRL,IRp60,LMIR1,Pigr4,MAIR-I,CLM-8,CD300a,CLM...
|
Cynomolgus
|
HEK293 Cells
|
|
CD300a is an inhibitory receptor for mast cells and eosinophils in allergic inflammation (AI); however, the spatiotemporal expression of CD300a and its potential roles in the resolution of AI are still to be determined.CD300a expression on peritoneal cells is regulated from inflammation to resolution. CD300a activation on mouse bone marrow-derived mast cells regulated ALX/FPR2 expression levels following IgE-mediated activation. CD300A Protein, Cynomolgus, Recombinant (Avi), Biotinylated is expr... |
|
TMPK-00186
|
CD300A Protein, Human, Recombinant (Avi)
Mcipr1,CLM-8,MAIR-I,IGSF12,NKRL,LMIR1,CLM8,IRC1,IRp60,CD300a...
|
Human
|
HEK293 Cells
|
|
CD300a is an inhibitory receptor for mast cells and eosinophils in allergic inflammation (AI); however, the spatiotemporal expression of CD300a and its potential roles in the resolution of AI are still to be determined.CD300a expression on peritoneal cells is regulated from inflammation to resolution. CD300a activation on mouse bone marrow-derived mast cells regulated ALX/FPR2 expression levels following IgE-mediated activation. CD300A Protein, Human, Recombinant (Avi) is expressed in HEK293 mam... |
|
TMPK-00559
|
CD300A Protein, Cynomolgus, Recombinant (Avi)
LMIR1,NKRL,CLM8,Mcipr1,Pigr4,IGSF12,MAIR-I,IRp60,IRC1,CLM-8,...
|
Cynomolgus
|
HEK293 Cells
|
|
CD300a is an inhibitory receptor for mast cells and eosinophils in allergic inflammation (AI); however, the spatiotemporal expression of CD300a and its potential roles in the resolution of AI are still to be determined.CD300a expression on peritoneal cells is regulated from inflammation to resolution. CD300a activation on mouse bone marrow-derived mast cells regulated ALX/FPR2 expression levels following IgE-mediated activation. CD300A Protein, Cynomolgus, Recombinant (Avi) is expressed in HEK29... |
|
TMPK-00665
|
GDF-15 Protein, Cynomolgus, Recombinant (His)
PTGFBPTGF-beta,PTGFBPTGF-β,MIC-1,NAG-1,MIC1,PTGF-beta,PTGF-β...
|
Cynomolgus
|
E. coli
|
|
Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and that GDF15 was necessary for surviving both bacterial and viral infections, as well as sepsis. The protective effects of GDF15 were largely independent of pathogen control or the magnitude of inflammatory response, suggesting a role in disease tolerance. GDF-15 Protein, Cynomolgus... |
|
TMPK-00663
|
GDF-15 Protein, Cynomolgus, Recombinant (hFc)
PTGF-β,GDF-15,NAG-1,PTGF-beta,PDF,PTGFBPTGF-beta,GDF15,Place...
|
Cynomolgus
|
HEK293 Cells
|
|
Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and that GDF15 was necessary for surviving both bacterial and viral infections, as well as sepsis. The protective effects of GDF15 were largely independent of pathogen control or the magnitude of inflammatory response, suggesting a role in disease tolerance. GDF-15 Protein, Cynomolgus... |
|
TMPH-02265
|
TNFAIP6 Protein, Human, Recombinant (His)
Hyaluronate-binding protein,TNF-stimulated gene 6 protein,Tu...
|
Human
|
E. coli
|
|
Possibly involved in cell-cell and cell-matrix interactions during inflammation and tumorigenesis. TNFAIP6 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 33.1 kDa and the accession number is P98066. |
|
TMPK-00187
|
CD300A Protein, Human, Recombinant (Avi), Biotinylated
Pigr4,LMIR1,IGSF12,CLM-8,CD300a,CLM8,IRC1,MAIR-I,Mcipr1,IRp6...
|
Human
|
HEK293 Cells
|
|
CD300a is an inhibitory receptor for mast cells and eosinophils in allergic inflammation (AI); however, the spatiotemporal expression of CD300a and its potential roles in the resolution of AI are still to be determined.CD300a expression on peritoneal cells is regulated from inflammation to resolution. CD300a activation on mouse bone marrow-derived mast cells regulated ALX/FPR2 expression levels following IgE-mediated activation. CD300A Protein, Human, Recombinant (Avi), Biotinylated is expressed... |
|
TMPK-01370
|
GRP-10 proform Protein, Canine, Recombinant (hFc)
Gastrin-releasing peptide,GRP
|
Canine
|
HEK293 Cells
|
|
Gastrin-releasing peptide (GRP) is a neuropeptide with growth-stimulatory and tumorigenic properties, and neuropeptides have previously been suggested to play a role in the complex cascade of chemical activity associated with periodontal inflammation. |
|
TMPK-01245
|
GDF-15 Protein (Primary Amine Labeling), Mouse, Recombinant (hFc), Biotinylated
RG-1,GDF15,Placental TGF-beta,GDF-15,PTGFBPTGF-beta,NAG-1,PT...
|
Mouse
|
HEK293 Cells
|
|
Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and that GDF15 was necessary for surviving both bacterial and viral infections, as well as sepsis. The protective effects of GDF15 were largely independent of pathogen control or the magnitude of inflammatory response, suggesting a role in disease tolerance. GDF-15 Protein (Primary Am... |
|
TMPK-00197
|
GDF-15 Protein (Primary Amine Labeling), Human, Recombinant (H202D, hFc), Biotinylated
Placental TGF-β,GDF15,RG-1,MIC-1,PTGFB,PTGF-beta,PDF,PTGF-β,...
|
Human
|
HEK293 Cells
|
|
Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and that GDF15 was necessary for surviving both bacterial and viral infections, as well as sepsis. The protective effects of GDF15 were largely independent of pathogen control or the magnitude of inflammatory response, suggesting a role in disease tolerance. GDF-15 Protein (Primary Am... |
|
TMPJ-01189
|
S100A15A Protein, Mouse, Recombinant
Protein S100-A15A,S100 calcium-binding protein A7A,Protein S...
|
Mouse
|
E. coli
|
|
Members of the S100 protein family are involved in calcium- or zinc-dependent cellular functions and regulate immune-mechanisms, cell proliferation and differentiation. Some S100 members have been established as tumor markers because they are dysregulated during carcinogenesis. Psoriasin (S100A7) and koebnerisin (S100A15) are highly homologous proteins that have been first described in psoriasis, which is characterized by disturbed epidermal maturation and chronic inflammation. Several studies s... |
|
TMPK-00101
|
IL-6 Protein, Cynomolgus, Recombinant (His)
CDF,BSF-2,白介素,IL6,HGF,白细胞介素,Interleukin-6,HSF,MGI-2A,IFN-β-2...
|
Cynomolgus
|
HEK293 Cells
|
|
IL-6 (Interleukin-6) is a pleiotropic cytokine that acts in the acute phase reaction, inflammation, hematopoiesis, bone metabolism, and cancer progression.Interleukin 6 has been shown to interact with interleukin-6 receptor and glycoprotein. |
|
TMPH-01951
|
S100A7A Protein, Human, Recombinant (His)
Protein S100-A7A,S100A7A,S100 calcium-binding protein A7A,S1...
|
Human
|
P. pastoris (Yeast)
|
|
May be involved in epidermal differentiation and inflammation and might therefore be important for the pathogenesis of psoriasis and other diseases. S100A7A Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 13.2 kDa and the accession number is Q86SG5. |
|
TMPK-00664
|
GDF-15 Protein (Primary Amine Labeling), Cynomolgus, Recombinant (hFc), Biotinylated
Placental TGF-beta,PTGFBPTGF-β,PLAB,MIC-1,GDF15,NAG-1,RG-1,P...
|
Cynomolgus
|
HEK293 Cells
|
|
Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and that GDF15 was necessary for surviving both bacterial and viral infections, as well as sepsis. The protective effects of GDF15 were largely independent of pathogen control or the magnitude of inflammatory response, suggesting a role in disease tolerance. GDF-15 Protein (Primary Am... |
|
TMPK-00198
|
GDF-15 Protein (Primary Amine Labeling), Human, Recombinant (hFc), Biotinylated
MIC-1,PTGFBPTGF-β,GDF15,PTGF-β,GDF-15,PTGF-beta,Placental TG...
|
Human
|
HEK293 Cells
|
|
Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and that GDF15 was necessary for surviving both bacterial and viral infections, as well as sepsis. The protective effects of GDF15 were largely independent of pathogen control or the magnitude of inflammatory response, suggesting a role in disease tolerance. GDF-15 Protein (Primary Am... |
|
TMPJ-00133
|
MBL2 Protein, Mouse, Recombinant
Mannose binding lectin (C),MBL-2,Mannose-binding protein C,M...
|
Mouse
|
HEK293 Cells
|
|
Mannose-binding Lectin (MBL) is an acute phase protein bearing to the family of collectins produced by the liver as a monomer that forms a triple helix. Once released in serum, it further polymerizes forming dimers to octamers. The degree of serum polymerization is critical for the biological activity of MBL. MBL has higher affinity to microbial polysaccharides or their glycoconjugates. MBL was shown earlier to bind cell surfaces of bacteria, fungi, protozoa and viruses and acts as an acute-phas... |
|
TMPJ-00658
|
CYR61/CCN1 Protein, Human, Recombinant (hFc)
Cysteine-rich angiogenic inducer 61,IGFBP10,Insulin-like gro...
|
Human
|
HEK293 Cells
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Protein CYR61, also known as CCN family member 1, Cysteine-rich angiogenic inducer 61,Insulin-like growth factor-binding protein 10 , GIG1, CYR61, CCN1 and IGFBP10, belongs to the CCN family, CYR61 is a secreted protein and contains one CTCK (C-terminal cystine knot-like) domain,one IGFBP N-terminal domain,one TSP type-1 domain and one VWFC domain. CYR61 promotes cell proliferation, chemotaxis, angiogenesis and cell adhesion. CYR61 plays important roles in inflammation and tissue repair. CYR61 ... |
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TMPK-01267
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TREM-1 Protein, Cynomolgus, Recombinant (His)
CD354,TREM-1
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Cynomolgus
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HEK293 Cells
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TREM1 (Triggering Receptor Expressed on Myeloid Cells 1) is a pro-inflammatory receptor expressed by phagocytes, which can also be released as a soluble molecule (sTREM1). The roles of TREM1 and sTREM1 in liver infection and inflammation are not clear. |
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TMPH-02973
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VDB Protein, Mouse, Recombinant (His)
Vitamin D-binding protein,Gc,Gc-globulin,Group-specific comp...
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Mouse
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P. pastoris (Yeast)
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Involved in vitamin D transport and storage, scavenging of extracellular G-actin, enhancement of the chemotactic activity of C5 alpha for neutrophils in inflammation and macrophage activation. VDB Protein, Mouse, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 53.9 kDa and the accession number is P21614. |
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TMPY-05321
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CYP3A4 Protein, Human, Recombinant (His)
P450C3,P450PCN1,CYPIIIA4,CP34,cytochrome P450 family 3 subfa...
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Human
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E. coli
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CYP3A4 is an important member of the cytochrome P450 enzyme superfamily, with 33 allelic variants. Human cytochrome P450 3A4 (CYP3A4) is an important drug metabolizing enzyme involved in a number of drug-drug and food-drug interactions. Systemic inflammation has been linked to suppressed CYP3A4 activity. |
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TMPH-03266
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CHI3L1 Protein, Rat, Recombinant (His)
Chi3l1,Cartilage glycoprotein 39,CGP-39,GP-39,Chitinase-3-li...
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Rat
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E. coli
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Carbohydrate-binding lectin with a preference for chitin. Has no chitinase activity. May play a role in tissue remodeling and in the capacity of cells to respond to and cope with changes in their environment. Plays a role in T-helper cell type 2 (Th2) inflammatory response and IL-13-induced inflammation, regulating allergen sensitization, inflammatory cell apoptosis, dendritic cell accumulation and M2 macrophage differentiation. Facilitates invasion of pathogenic enteric bacteria into colonic mu... |
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TMPJ-00682
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CD39L1 Protein, Mouse, Recombinant (His)
Ectonucleoside triphosphate diphosphohydrolase 2,Entpd2
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Mouse
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HEK293 Cells
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CD39L1 protein (ENTPD2 or NTPDase2) is a member of the ecto-nucleoside triphosphate diphosphohydrolase family which the main role is termination of purinergic signaling. CD39L1 gene encodes a precursor protein with 495 amino acid residues which generates a 437 amino acid residues mature protein after processing. It is an ecto-nucleotidase that found on the surface of vascular adventitial cells and accessory vascular cells. CD39L1 is a Ca2+- and Mg2+-dependent enzyme that activates platelets by p... |
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TMPJ-01252
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CLEC2D Protein, Mouse, Recombinant (His)
Clec2d,Clr-b,Clrb,Ocil,Osteoclast inhibitory lectin,C-type l...
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Mouse
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HEK293 Cells
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C-type lectin domain family 2, member D (CLEC2D) is implicated in the immune response. Sensing tissue damage is an ancient function of immune cells that is central to the regulation of inflammation, tissue repair, and immunity. The C-type lectin receptor Clec2d as a sensor of cell death, which directly detects histones released during necrosis and thus contributes to inflammation and immunopathology. The Clec2d pathway may also be exploited to favor a pro-inflammatory anti-tumor response. And tu... |
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