购物车
- 全部删除
- 您的购物车当前为空
β-Aminoarteether maleate (SM934) 是一种来源于 Artemisinin 的口服活性衍生物。该化合物主要用于研究炎症和自身免疫性疾病,如狼疮疾病。
β-Aminoarteether maleate (SM934) 是一种来源于 Artemisinin 的口服活性衍生物。该化合物主要用于研究炎症和自身免疫性疾病,如狼疮疾病。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
10 mg | 询价 | 10-14周 | |
50 mg | 询价 | 10-14周 |
产品描述 | β-Aminoarteether maleate (SM934), an orally active derivative of Artemisinin, is utilized in the research of inflammation and autoimmune diseases, including lupus [1]. |
体外活性 | β-Aminoarteether (SM934; 10 µM; 24 hours) treatment directly enhances IL-10 production and suppresses IL-12/23p40 production in primary peritoneal macrophages with IFN-γ stimulation.[1] In vitro, β-Aminoarteether (SM934) suppresses Th1 and Th17 polarization without influencing Treg differentiation.[1] |
体内活性 | The treatment with β-Aminoarteether (SM934; 1-10 mg/kg; oral administration; daily; for 3 months) significantly delays the progression of glomerulonephritis and increases survival rates in female NZB/W F1 mice (six and half months old). Additionally, β-Aminoarteether treatment promotes IL-10 production by macrophages from these mice [1]. |
别名 | SM934 |
分子量 | 443.49 |
分子式 | C21H33NO9 |
CAS No. | 133162-25-1 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
版权所有©2015-2024 TargetMol Chemicals Inc.保留所有权利.