|
TMPY-04644
|
PDGFB Protein, Human, Recombinant (His)
platelet-derived growth factor beta polypeptide,SSV,c-sis,SI...
|
Human
|
P. pastoris (Yeast)
|
|
Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by increasing periendothelial coverage and vascular functionality. Interestingly, this effect exerted by PDGFB was also observed in the presence of DAPT. So PDGFB is able to improve tumor vascularity and allows the anticancer action of DAPT in the tumor. PDGFB Protein, Human, Recombinant (His) is expressed in yeast with His tag. The predicted... |
|
TMPH-02823
|
Peptide YY/PYY Protein, Mouse, Recombinant (GST)
Peptide tyrosine tyrosine,Pyy,Peptide YY
|
Mouse
|
E. coli
|
|
This gut peptide inhibits exocrine pancreatic secretion, has a vasoconstrictory action and inhibitis jejunal and colonic mobility. |
|
TMPH-02911
|
STC2 Protein, Mouse, Recombinant
Stc2,Stanniocalcin-2
|
Mouse
|
E. coli
|
|
Has an anti-hypocalcemic action on calcium and phosphate homeostasis. STC2 Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 30.1 kDa and the accession number is O88452. |
|
TMPH-01294
|
EDNRA Protein, Human, Recombinant (His)
ET-A,Endothelin-1 receptor,hET-AR,ETA-R,ETRA,EDNRA,ETA
|
Human
|
P. pastoris (Yeast)
|
|
Receptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3. |
|
TMPH-01770
|
Neurotrypsin Protein, Human, Recombinant (His & SUMO)
PRSS12,Motopsin,Serine protease 12,Leydin,Neurotrypsin
|
Human
|
E. coli
|
|
Plays a role in neuronal plasticity and the proteolytic action may subserve structural reorganizations associated with learning and memory operations. Neurotrypsin Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 43.4 kDa and the accession number is P56730. |
|
TMPH-03338
|
CHRM1 Protein, Rat, Recombinant (His)
Muscarinic acetylcholine receptor M1,CHRM1
|
Rat
|
E. coli
|
|
The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover. CHRM1 Protein, Rat, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 21.1 kDa and the accession number is P08482. |
|
TMPH-01852
|
Peptide YY/PYY Protein, Human, Recombinant (GST)
Peptide tyrosine tyrosine,PYY-I,PYY,Peptide YY
|
Human
|
E. coli
|
|
This gut peptide inhibits exocrine pancreatic secretion, has a vasoconstrictory action and inhibitis jejunal and colonic mobility. Peptide YY/PYY Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 31.1 kDa and the accession number is P10082. |
|
TMPH-00716
|
RzoR Protein, E. coli, Recombinant (Flag & His)
Prophage outer membrane lipoprotein RzoR,Spanin from lambdoi...
|
E. coli
|
E. coli
|
|
Component of the spanin complex that disrupts the outer membrane and causes cell lysis during virus exit. The spanin complex conducts the final step in cell lysis by disrupting the outer membrane after holin and endolysin action have permeabilized the inner membrane and degraded the host peptidoglycans. |
|
TMPH-01717
|
CHRM5 Protein, Human, Recombinant (His)
CHRM5,Muscarinic acetylcholine receptor M5
|
Human
|
E. coli
|
|
The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover. CHRM5 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 31.5 kDa and the accession number is P08912. |
|
TMPH-03607
|
HOE-467A Protein, Streptomyces tendae, Recombinant (His & Myc & SUMO)
Tendamistat,Alpha-amylase inhibitor HOE-467A
|
Streptomyces tendae
|
E. coli
|
|
Inhibits mammalian alpha-amylases specifically but has no action on plant and microbial alpha-amylases. Forms a tight stoichiometric 1:1 complex with alpha-amylase. HOE-467A Protein, Streptomyces tendae, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Myc tag. The predicted molecular weight is 28.0 kDa and the accession number is P01092. |
|
TMPH-01716
|
CHRM3 Protein, Human, Recombinant (B2M & His)
Muscarinic acetylcholine receptor M3,CHRM3
|
Human
|
E. coli
|
|
The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover. CHRM3 Protein, Human, Recombinant (B2M & His) is expressed in E. coli expression system with N-6xHis-B2M tag. The predicted molecular weight is 40.7 kDa and the accession number is P20309. |
|
TMPH-01714
|
CHRM1 Protein, Human, Recombinant (His)
Muscarinic acetylcholine receptor M1,CHRM1
|
Human
|
E. coli
|
|
The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover. CHRM1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 20.8 kDa and the accession number is P11229. |
|
TMPH-02119
|
SLC5A2 Protein, Human, Recombinant (His & Myc)
Solute carrier family 5 member 2,Low affinity sodium-glucose...
|
Human
|
E. coli
|
|
Sodium-dependent glucose transporter. Has a Na(+) to glucose coupling ratio of 1:1.; Efficient substrate transport in mammalian kidney is provided by the concerted action of a low affinity high capacity and a high affinity low capacity Na(+)/glucose cotransporter arranged in series along kidney proximal tubules. |
|
TMPH-03210
|
TFPI Protein, Rabbit, Recombinant (E. coli, His)
Lipoprotein-associated coagulation inhibitor,Extrinsic pathw...
|
Rabbit
|
E. coli
|
|
Inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability to associate with lipoproteins in plasma. TFPI Protein, Rabbit, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 35.8 kDa and the accession number is P19761. |
|
TMPJ-00191
|
FSTL1 Protein, Human, Recombinant
FRP,Follistatin-Related Protein 1,Follistatin-Like Protein 1...
|
Human
|
E. coli
|
|
Follistatin-Related Protein 1 (FSTL1) is a secreted protein that contains two EF-hand domains, one follistatin-like domain, one Kazal-like domain, and one VWFC domain. Its functional significance in physiological and pathological processes is not completely understood. However, FSTL1 is thought to modulate the action of some growth factors on cell proliferation and differentiation. FSTL1 maybe an autoantigen associated with rheumatoid arthritis. |
|
TMPH-01672
|
Human metapneumovirus (strain CAN97-83) Matrix protein (His & Myc)
M,Matrix protein,M protein
|
HMPV
|
E. coli
|
|
Plays a crucial role in virus assembly into filaments and budding. Early in infection, localizes in the nucleus where it may inhibit host cell transcription. Later in infection, traffics to the cytoplasm through the action of host CRM1 to associate with inclusion bodies, the site of viral transcription and replication. During virus assembly and budding, acts as a bridge between the nucleocapsid and the lipid bilayer. |
|
TMPK-00861
|
A2AR Protein-VLP, Human, Recombinant
RDC8,Adenosine A2a R,ADORA2,ADORA 2,ADORA2A,A2aR
|
Human
|
HEK293 Cells
|
|
Adenosine is a neuromodulator in the adult central nervous system. Membrane-bound receptors for adenosine have been identified and cDNAs for A1, A2a, A2b, and A3 adenosine receptor subtypes have been cloned recently.Expression of A2a adenosine receptor mRNA in cranial ganglia, carotid body, and intermediate lobe of the pituitary gland similarly suggests novel sites of adenosine action during development and in the adult. |
|
TMPH-01673
|
Human metapneumovirus (strain CAN97-83) Matrix protein (His)
M,Matrix protein,M protein
|
HMPV
|
P. pastoris (Yeast)
|
|
Plays a crucial role in virus assembly into filaments and budding. Early in infection, localizes in the nucleus where it may inhibit host cell transcription. Later in infection, traffics to the cytoplasm through the action of host CRM1 to associate with inclusion bodies, the site of viral transcription and replication. During virus assembly and budding, acts as a bridge between the nucleocapsid and the lipid bilayer. |
|
TMPH-02203
|
THRA Protein, Human, Recombinant (His)
c-erbA-1,c-erbA-alpha,THRA,Thyroid hormone receptor alpha,V-...
|
Human
|
E. coli
|
|
Nuclear hormone receptor that can act as a repressor or activator of transcription. High affinity receptor for thyroid hormones, including triiodothyronine and thyroxine.; Does not bind thyroid hormone and functions as a weak dominant negative inhibitor of thyroid hormone action. THRA Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 58.9 kDa and the accession number is P10827. |
|
TMPH-03260
|
Carboxypeptidase A1 Protein, Rat, Recombinant (His & Myc)
Cpa1,Carboxypeptidase A1,Cpa
|
Rat
|
E. coli
|
|
Carboxypeptidase that catalyzes the release of a C-terminal amino acid, but has little or no action with -Asp, -Glu, -Arg, -Lys or -Pro. Catalyzes the conversion of leukotriene C4 to leukotriene F4 via the hydrolysis of an amide bond. Carboxypeptidase A1 Protein, Rat, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 39.6 kDa and the accession number is P00731. |
|
TMPH-03211
|
TFPI Protein, Rabbit, Recombinant (His)
TFPI,Lipoprotein-associated coagulation inhibitor,Extrinsic ...
|
Rabbit
|
HEK293 Cells
|
|
Inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability to associate with lipoproteins in plasma. TFPI Protein, Rabbit, Recombinant (His) is expressed in HEK293 mammalian cells with N-10xHis tag. The predicted molecular weight is 35.4 kDa and the accession number is P19761. |
|
TMPY-02395
|
PDGFB Protein, Cynomolgus, Recombinant (mFc)
血小板源生长因子,platelet-derived growth factor beta polypeptide,pla...
|
Cynomolgus
|
HEK293 Cells
|
|
Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by increasing periendothelial coverage and vascular functionality. Interestingly, this effect exerted by PDGFB was also observed in the presence of DAPT. So PDGFB is able to improve tumor vascularity and allows the anticancer action of DAPT in the tumor. PDGFB Protein, Cynomolgus, Recombinant (mFc) is expressed in HEK293 mammalian cells with ... |
|
TMPH-00120
|
Ribonuclease clavin Protein, Aspergillus clavatus, Recombinant (His & Myc)
cla,Ribonuclease clavin
|
Aspergillus clavatus
|
E. coli
|
|
Clavin has the same substrate specificity as alpha-sarcin. It is specific for purines in both single- and double-stranded RNA. Its toxic action on eukaryotic cells is the result of cleavage of a single phosphodiester bond in the 60S subunit of ribosomes. Ribonuclease clavin Protein, Aspergillus clavatus, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 24.5 kDa and the accession number is P0CL71. |
|
TMPH-00890
|
DBI Protein, Human, Recombinant (aa 2-104, His)
Acyl-CoA-binding protein,Diazepam-binding inhibitor,DBI,Endo...
|
Human
|
E. coli
|
|
Binds medium- and long-chain acyl-CoA esters with very high affinity and may function as an intracellular carrier of acyl-CoA esters. It is also able to displace diazepam from the benzodiazepine (BZD) recognition site located on the GABA type A receptor. It is therefore possible that this protein also acts as a neuropeptide to modulate the action of the GABA receptor. DBI Protein, Human, Recombinant (aa 2-104, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecul... |
|
TMPY-05076
|
PDGFB Protein, Canine, Recombinant (His)
platelet-derived growth factor beta polypeptide,platelet-der...
|
Canine
|
P. pastoris (Yeast)
|
|
Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by increasing periendothelial coverage and vascular functionality. Interestingly, this effect exerted by PDGFB was also observed in the presence of DAPT. So PDGFB is able to improve tumor vascularity and allows the anticancer action of DAPT in the tumor. PDGFB Protein, Canine, Recombinant (His) is expressed in yeast with His tag. The predicte... |
|
TMPH-01715
|
CHRM2 Protein, Human, Recombinant (His)
CHRM2,Muscarinic acetylcholine receptor M2
|
Human
|
E. coli
|
|
The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is adenylate cyclase inhibition. Signaling promotes phospholipase C activity, leading to the release of inositol trisphosphate (IP3); this then triggers calcium ion release into the cytosol. CHRM2 Protein, Human, Recombinant (His) is expressed in E. col... |
|
TMPH-00589
|
SpoT Protein, E. coli, Recombinant (His & Myc)
Bifunctional (p)ppGpp synthase/hydrolase SpoT,spoT
|
E. coli
|
E. coli
|
|
In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response which coordinates a variety of cellular activities in response to changes in nutritional abundance. This enzyme catalyzes both the synthesis and degradation of ppGpp. The second messengers ppGpp and c-di-GMP together control biofilm formation in response to translational stress; ppGpp represses biofilm formation while c-di-GMP induces it. ppGpp activates transcription of CsrA-antagonistic small ... |
|
TMPY-03182
|
PLRP2 Protein, Human, Recombinant (His)
PLRP2,pancreatic lipase-related protein 2
|
Human
|
Baculovirus Insect Cells
|
|
Galactolipase, also known as PNLIPRP2, is a lipase with broad substrate specificity. It can hydrolyze both phospholipids and galactolipids. Galactolipase acts preferentially on monoglycerides, phospholipids and galactolipids. It also hydrolyses milk fat with a lower catalytic efficiency. The expressed galactolipase shows a lipolytic activity that is, however, only marginally dependent on the presence of colipase. The lipolytic activity of pancreatic extracts and human pancreatic juice on Labraso... |
|
TMPY-00554
|
CHRNB3 Protein, Human, Recombinant (His)
cholinergic receptor, nicotinic, beta 3 (neuronal),cholinerg...
|
Human
|
HEK293 Cells
|
|
Cholinergic nicotinic receptor (CHRN) gene family has been known to mediate the highly additive effects of nicotine in the body, and implicated nicotine dependence (ND) and related phenotypes. Cigarette smoking is protective in Parkinson's disease (PD), possibly because of nicotine action on brain nicotinic-acetylcholine receptors. The beta3 nicotinic-acetylcholine receptor subunit (encoded by CHRNB3) is depleted in the striatum of PD patients and associated with nicotine dependence. CHRNB3 Prot... |
|
TMPK-01285
|
FSHB Protein, Cynomolgus, Recombinant (His)
Follitropin,FSH-B,FSH-beta,FSH-β,FSHB
|
Cynomolgus
|
HEK293 Cells
|
|
Fertility is dependent on follicle-stimulating hormone (FSH), a product of gonadotrope cells of the anterior pituitary gland. Hypothalamic gonadotropin-releasing hormone (GnRH) and intra-pituitary activins are regarded as the primary drivers of FSH synthesis and secretion. Both stimulate expression of the FSH beta subunit gene (Fshb), although the underlying mechanisms of GnRH action are poorly described relative to those of the activins. FSHB Protein, Cynomolgus, Recombinant (His) is expressed ... |
|
TMPH-03235
|
DBI Protein, Rat, Recombinant (His & Myc)
Endozepine (EP),ACBP,DBI,Acyl-CoA-binding protein,Diazepam-b...
|
Rat
|
E. coli
|
|
Binds medium- and long-chain acyl-CoA esters with very high affinity and may function as an intracellular carrier of acyl-CoA esters. It is also able to displace diazepam from the benzodiazepine (BZD) recognition site located on the GABA type A receptor. It is therefore possible that this protein also acts as a neuropeptide to modulate the action of the GABA receptor. DBI Protein, Rat, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted mo... |
|
TMPY-05077
|
PDGFB Protein, Rhesus, Recombinant (His)
platelet-derived growth factor β polypeptide,platelet-derive...
|
Rhesus
|
P. pastoris (Yeast)
|
|
Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by increasing periendothelial coverage and vascular functionality. Interestingly, this effect exerted by PDGFB was also observed in the presence of DAPT. So PDGFB is able to improve tumor vascularity and allows the anticancer action of DAPT in the tumor. PDGFB Protein, Rhesus, Recombinant (His) is expressed in yeast with His tag. The predicte... |
|
TMPK-01020
|
FSHB Protein, Mouse, Recombinant (hFc)
FSH-beta,FSH-B,FSHB,FSH-β,Follitropin
|
Mouse
|
HEK293 Cells
|
|
Fertility is dependent on follicle-stimulating hormone (FSH), a product of gonadotrope cells of the anterior pituitary gland. Hypothalamic gonadotropin-releasing hormone (GnRH) and intra-pituitary activins are regarded as the primary drivers of FSH synthesis and secretion. Both stimulate expression of the FSH beta subunit gene (Fshb), although the underlying mechanisms of GnRH action are poorly described relative to those of the activins. FSHB Protein, Mouse, Recombinant (hFc) is expressed in HE... |
|
TMPH-02492
|
DBI Protein, Mouse, Recombinant (His & Myc)
Endozepine (EP),Diazepam-binding inhibitor,DBI,Acyl-CoA-bind...
|
Mouse
|
E. coli
|
|
Binds medium- and long-chain acyl-CoA esters with very high affinity and may function as an intracellular carrier of acyl-CoA esters. It is also able to displace diazepam from the benzodiazepine (BZD) recognition site located on the GABA type A receptor. It is therefore possible that this protein also acts as a neuropeptide to modulate the action of the GABA receptor. DBI Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted ... |
|
TMPJ-01192
|
ELAPOR1 Protein, Human, Recombinant (His)
ELAPOR1,Endosome-Lysosome Associated Apoptosis And Autophagy...
|
Human
|
HEK293 Cells
|
|
Endosome/lysosome-associated apoptosis and autophagy regulator (ELAPOR1), also known as EIG121 protein, is a type I transmembrane protein induced by estrogen. The estrogen-induced gene 121 (EIG121) has been associated with breast and endometrial cancers,but its mechanism of action remains unknown.May protect cells from cell death by inducing cytosolic vacuolization and upregulating the autophagy pathway. That EIG121 is a good endometrial biomarker associated with a hyperestrogenic state and estr... |
|
TMPK-00109
|
Artemin Protein, Human, Recombinant (hFc)
ARTNE,ARTN,Neublastin,Enovin,Artemin,NBN,EVN
|
Human
|
HEK293 Cells
|
|
Artemin (ARTN) is a member of glial cell line-derived neurotrophic factor (GDNF) family of ligands, and its signaling is mediated via a multi-component receptor complex including the glycosylphosphatidylinositol-anchored GDNF family receptors a (GFRa1, GFRa3) and RET receptor tyrosine kinase. The major mechanism of ARTN action is via binding to a non-signaling co-receptor. The major function of ARTN is to drive the molecule to induce migration and axonal projection from sympathetic neurons. |
|
TMPY-04877
|
PDGFB Protein, Mouse, Recombinant (His)
platelet-derived growth factor β polypeptide,血小板源生长因子,Sis,pl...
|
Mouse
|
P. pastoris (Yeast)
|
|
Platelet-derived growth factor-B (PDGFB) is necessary for normal cardiovascular development. The administration of PDGFB alone normalized tumor vasculature by increasing periendothelial coverage and vascular functionality. Interestingly, this effect exerted by PDGFB was also observed in the presence of DAPT. So PDGFB is able to improve tumor vascularity and allows the anticancer action of DAPT in the tumor. PDGFB Protein, Mouse, Recombinant (His) is expressed in yeast with His tag. The predicted... |
|
TMPJ-00650
|
FIBP Protein, Human, Recombinant
FIBP,aFGF Intracellular-Binding Protein,FGF-1 Intracellular-...
|
Human
|
E. coli
|
|
Acidic Fibroblast Growth Factor Intracellular-Binding Protein (FIBP) is highly expressed in the heart, skeletal muscle, and pancreas. Acidic Fibroblast Growth Factor is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FIBP is an intracellular protein that binds ... |
|
TMPJ-01050
|
GRB2 Protein, Human, Recombinant (His)
Growth Factor Receptor-Bound Protein 2,SH2/SH3 Adapter GRB2,...
|
Human
|
E. coli
|
|
As an adaptor protein, Growth Factor Receptor-Bound Protein 2 (GRB2) is involved in siganl transduction and consists of a central SH2 domain flanked by two SH3 domains. GRB2 associates with activated Tyr-phosphorylated EGF receptor/EGFR and PDGF receptors via its SH2 domain, stimulating GTP binding to Ras, which in turn activates MAPK and other signaling pathway.It also associates to other cellular Tyr-phosphorylated proteins such as SIT1, IRS1, IRS4, SHC and LNK. probably via the concerted acti... |
|
TMPY-04195
|
CHRNB3 Protein, Human, Recombinant (hFc)
cholinergic receptor, nicotinic, β 3 (neuronal),cholinergic ...
|
Human
|
HEK293 Cells
|
|
Cholinergic nicotinic receptor (CHRN) gene family has been known to mediate the highly additive effects of nicotine in the body, and implicated nicotine dependence (ND) and related phenotypes. Cigarette smoking is protective in Parkinson's disease (PD), possibly because of nicotine action on brain nicotinic-acetylcholine receptors. The beta3 nicotinic-acetylcholine receptor subunit (encoded by CHRNB3) is depleted in the striatum of PD patients and associated with nicotine dependence. CHRNB3 Prot... |
|
TMPJ-01310
|
TRIM5 Protein, Human, Recombinant (His)
RNF88,Tripartite motif-containing protein 5,RING finger prot...
|
Human
|
E. coli
|
|
Tripartite motif-containing Motif 5 is a protein that in humans is encoded by the TRIM5 gene.It is a 493 amino acids protein that belongs to the TRIM/RBCC family.It contains 1 B box-type zinc finger, 1 B30.2/SPRY domain and 1 RING-type zinc finger. TRIM5 present in the cytoplasm recognizes motifs within the capsid proteins and interferes with the uncoating process, therefore preventing successful reverse transcription and transport to the nucleus of the viral genome. The exact mechanism of actio... |
|
TMPY-03990
|
Profilin 4 Protein, Human, Recombinant (His)
profilin family, member 4
|
Human
|
E. coli
|
|
PFN4, also known as profilin 4, is a member of the profilin family. Profilin can be detected in all eukaryotic organisms. It plays an important role in the spatially and temporally controlled growth of actin microfilaments. Profilin is one of the most abundant actin monomer binders, but proteins such as CAP and (in mammals) thymosin β4 have some functional overlaps with profilin. In contrast, ADF/cofilin has some properties that antagonize profilin action. PFN4 also functions in the dynamic turn... |
|
TMPJ-00553
|
Lp-PLA2/PLA2G7 Protein, Human, Recombinant (aa 22-441, His)
PAF Acetylhydrolase,LDL-Associated Phospholipase A2,LDL-PLA(...
|
Human
|
HEK293 Cells
|
|
Platelet-Activating Factor Acetylhydrolase (PAFAH) is a secreted enzyme which belongs to the AB hydrolase superfamily and Lipase family and catalyzes the degradation of platelet-activating factor to biologically inactive products. PAFAH is produced by inflammatory cells and hydrolyzes oxidised phospholipids in LDL. PAFAH has been implicated in the development of atherosclerosis and has also been identified as a marker for cardiac disease. PAFAH might have a major physiologic effect in the presen... |
|
TMPJ-00891
|
Kallikrein 2/KLK2 Protein, Human, Recombinant (His)
hGK-1,Kallikrein-2,Tissue Kallikrein-2,KLK2,Glandular Kallik...
|
Human
|
HEK293 Cells
|
|
Kallikrein-2 (KLK2) is a secreted serine protease that belongs to the peptidase S1 family of Kallikrein subfamily. KLK2 contains 1 peptidase S1 domain. It is highly expressed in the human prostate gland. KLK2 can cleave Met-Lys and Arg-Ser bonds in kininogen to release Lys-bradykinin, but Preferential cleavages of Arg-|-Xaa bonds in small molecule substrates. It also highly selective action to release kallidin (lysyl-bradykinin) from kininogen involves hydrolysis of Met-|-Xaa or Leu-|-Xaa. KLK2 ... |
|
TMPJ-00660
|
IMPase2 Protein, Human, Recombinant (His)
Inositol-1(or 4)-Monophosphatase 2,IMPA2,IMP 2,IMPase 2,Inos...
|
Human
|
E. coli
|
|
Inositol monophosphatase 2, also known as Inositol-1(or 4)-monophosphatase 2, Myo-inositol monophosphatase A2 and IMPA2, is an enzyme which belongs to the inositol monophosphatase family. IMPA2 catalyzes the dephosphoylration of inositol monophosphate with cofactor Magnesium and Inhibited by high Li+ and restricted Mg2+ concentrations. IMPA2 plays an important role in phosphatidylinositol signaling. IMPA2 can use the myo-inositol monophosphates, scylloinositol 1,4-diphosphate, glucose-1-phosphat... |
|
TMPJ-01374
|
UPB1 Protein, Human, Recombinant (His)
β-Ureidopropionase,Beta-Alanine Synthase,β-Alanine Synthase,...
|
Human
|
E. coli
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β-Ureidopropionase is a cytoplasmic protein which belongs to the CN hydrolase family of BUP subfamily. β-Ureidopropionase binds one zinc ion per subunit, catalyzes the last step in the pyrimidine degradation pathway. β-Ureidopropionase can convert N-carbamyl-beta-aminoisobutyric acid and N-carbamyl-beta-alanine to beta-aminoisobutyric acid and beta-alanine, ammonia and carbon dioxide, respectively. The pyrimidine bases uracil and thymine are degraded via the consecutive action of dihydropyrimidi... |
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TMPJ-01427
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SARS-CoV-2 NSP7 Protein (His)
SARS-CoV 2 nsp7
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SARS-CoV-2
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E. coli
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The ∼30kb positive-stranded RNA genome of coronaviruses encodes a replication/transcription machinery that is unusually complex and composed of 16 nonstructural proteins (nsps). The four proteins nsp7 to nsp10, which are conserved among all CoVs but have no functional homologs outside of the Coronaviridae, are translated as part of the viral polyproteins pp1a and pp1ab, and the mature proteins are released by the action of the SARS-CoV protease nsp5. Hexadecamer of nsp7 and nsp8 may possess dsRN... |
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TMPY-03616
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NAPG Protein, Human, Recombinant (His)
γSNAP,GAMMASNAP,N-ethylmaleimide-sensitive factor attachment...
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Human
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E. coli
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NAPG (NSF Attachment Protein Gamma, also known as gamma SNAP) is a Protein Coding gene. This gene encodes soluble NSF attachment protein gamma. The encoded protein mediates platelet exocytosis and controls the membrane fusion events of this process. NAPG is required for vesicular transport between the endoplasmic reticulum and the Golgi apparatus. NAPG belongs to the SNAP family. It is widely expressed in the brain, thyroid, and other tissues. SNAPs enable N-ethyl-maleimide-sensitive fusion prot... |
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TMPY-03269
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Prolyl Endopeptidase Protein, Mouse, Recombinant (His)
PEP,AI450383,AI047692,D10Wsu136e,prolyl endopeptidase,Pop
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Mouse
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Baculovirus Insect Cells
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Prolyl endopeptidase, also known as PREP, belongs to a distinct class of serine peptidases. It is a large cytosolic enzyme which was first described in the cytosol of rabbit brain as an oligopeptidase. Prolyl endopeptidase degrades the nonapeptide bradykinin at the Pro-Phe bond. It is involved in the maturation and degradation of peptide hormones and neuropeptides such as alpha-melanocyte-stimulating hormone, luteinizing hormone-releasing hormone (LH-RH), thyrotropin-releasing hormone, angiotens... |
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TMPJ-00914
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YY1 Protein, Human, Recombinant (His)
NF-E1,Transcriptional repressor protein YY1,Yin and yang 1,I...
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Human
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E. coli
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Transcriptional repressor protein YY1（YY1）contains 4 C2H2-type zinc fingers and belongs to the YY transcription factor family. Multifunctional transcription factor exhibits positive and negative control on a large number of cellular and viral genes by binding to sites overlapping the transcription start site. The effect on transcription regulation of the protein is depending upon the context in which it binds and diverse mechanisms of action include direct activation or repression, indirect acti... |
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