购物车
- 全部删除
- 您的购物车当前为空
DL-threo-PPMP 作为一种抑制剂,有效地针对疟原虫 (Plasmodium falciparum) 中的鞘氨醇合成酶 (sphingosine synthetase).通过模拟鞘氨醇的底物,DL-threo-PPMP 与该酶结合,进而抑制其活性.这种作用导致宿主细胞内TVM的管状网络被选择性地破坏,并迅速降低了敏感的鞘氨醇合成酶活性,有效阻断疟原虫的繁殖过程.DL-threo-PPMP 常被应用于疟原虫生物学研究及新型抗疟策略的开发.
DL-threo-PPMP 作为一种抑制剂,有效地针对疟原虫 (Plasmodium falciparum) 中的鞘氨醇合成酶 (sphingosine synthetase).通过模拟鞘氨醇的底物,DL-threo-PPMP 与该酶结合,进而抑制其活性.这种作用导致宿主细胞内TVM的管状网络被选择性地破坏,并迅速降低了敏感的鞘氨醇合成酶活性,有效阻断疟原虫的繁殖过程.DL-threo-PPMP 常被应用于疟原虫生物学研究及新型抗疟策略的开发.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
10 mg | 询价 | 10-14周 | |
50 mg | 询价 | 10-14周 |
产品描述 | DL-threo-PPMP is an inhibitor of sphingosine synthetase (sphingosine synthetase) in Plasmodium falciparum. It inhibits the enzymes activity by binding to it, mimicking the substrate of sphingosine. This inhibition results in a rapid decline in the activity of sensitive sphingosine synthetase, selectively disrupting the interconnected tubular network in the cytoplasm of the host cell at the TVM. This action also blocks the proliferation of the Plasmodium falciparum. DL-threo-PPMP is valuable in studies of Plasmodium falciparum biology and the development of new anti-malarial strategies. |
分子量 | 474.72 |
分子式 | C29H50N2O3 |
CAS No. | 149022-18-4 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
版权所有©2015-2024 TargetMol Chemicals Inc.保留所有权利.