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463

抑制剂 & 化合物

103

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同位素标记化合物

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Cat. No. Product Name
L8710 铜死亡化合物库

400 compounds
TargetMol 铜死亡化合物库集合了 400 种与铜死亡相关的化合物,可以用于铜死亡机制及相关疾病研究
L8700 铁死亡化合物库

779 compounds
779 种与铁死亡通路相关的化合物,可用于高通量和高内涵筛选;
L9000 细胞凋亡化合物库

1760 compounds
1760 种与凋亡相关的生物活性小分子化合物的特有集合,多用于研究肿瘤发生发展机制和抗癌药物筛选等。可用于高通量筛选和高内涵筛选;
L4510 抗寄生虫库

419 compounds
419 种具有抗寄生虫活性的小分子化合物;
L1380 转录因子库

695 compounds
695 种转录因子靶向、结构新颖的化合物;
L9810 抗纤维化化合物库

1180 compounds
1180 种潜在的抗纤维化分子,是研究纤维化的有效工具,可以用于高通量筛选和高内涵筛选;
L2192 抗胰腺癌化合物库

2238 compounds
2238 种与胰腺癌相关的化合物,可以用于高通量和高内涵筛选;
L5400 抗心血管疾病化合物库

1408 compounds
1408 种心血管疾病相关的生物活性小分子化合物的特有集合,用于高通量、高内涵筛选;
L2160 抗癌活性化合物库

3188 compounds
3188 种具有抗肿瘤活性的化合物的特有集合,用于高通量、高内涵筛选;
L2150 抗癌药物库

3080 compounds
3080 个具有抗癌活性小分子的独特集合,生物活性已经临床前实验证实,可用于高通量、高内涵筛选;
L2100 抗癌化合物库

7234 compounds
7234 种肿瘤相关的生物活性小分子化合物的特有集合,用于高通量、高内涵筛选;
L2120 抗癌临床化合物库

2545 compounds
2545 个具有抗癌活性小分子的独特集合,可用于高通量高内涵筛选。
L3700 JAK-STAT 化合物库

252 compounds
252 个 JAK/STAT 靶点相关的小分子化合物的独特集合,用于高通量、高内涵筛选;
L2110 抗癌上市药物库

1779 compounds
1779 个具有抗癌活性小分子的独特集合,所有化合物都经过了严格的临床前研究和临床试验,由FDA、EMA 或NMPA 批准上市,可用于高通量、高内涵筛选。
L2180 抗肿瘤库Plus

1468 compounds
1468 种抗肿瘤相关、结构新颖的化合物;
L2140 癌细胞分化化合物库

406 compounds
406 个诱导肿瘤细胞分化化合物的独特集合,可用于高通量筛选和高内涵筛选;
L1110 微管靶向化合物库

142 compounds
142 种靶向微管的分子集合,用于高通量筛选和高内涵筛选;
L2191 抗乳腺癌化合物库

1939 compounds
1939 种与乳腺癌相关的化合物,可以用于抗乳腺癌药物研发和药理研究;
L5300 线粒体靶向库

812 compounds
812 种具有潜在或确定线粒体靶向活性的化合物,以促进针对线粒体的药物研究;
L9840 抗阿尔茨海默症化合物库

986 compounds
986 种阿尔茨海默症相关的化合物集合,可用于高通量和高内涵筛选;

化合物库

铜死亡化合物库
Cat.No: L8710
Compounds: 400
铁死亡化合物库
Cat.No: L8700
Compounds: 779
细胞凋亡化合物库
Cat.No: L9000
Compounds: 1760
抗寄生虫库
Cat.No: L4510
Compounds: 419
转录因子库
Cat.No: L1380
Compounds: 695
抗纤维化化合物库
Cat.No: L9810
Compounds: 1180
抗胰腺癌化合物库
Cat.No: L2192
Compounds: 2238
抗心血管疾病化合物库
Cat.No: L5400
Compounds: 1408
抗癌活性化合物库
Cat.No: L2160
Compounds: 3188
抗癌药物库
Cat.No: L2150
Compounds: 3080
抗癌化合物库
Cat.No: L2100
Compounds: 7234
抗癌临床化合物库
Cat.No: L2120
Compounds: 2545
JAK-STAT 化合物库
Cat.No: L3700
Compounds: 252
抗癌上市药物库
Cat.No: L2110
Compounds: 1779
抗肿瘤库Plus
Cat.No: L2180
Compounds: 1468
癌细胞分化化合物库
Cat.No: L2140
Compounds: 406
微管靶向化合物库
Cat.No: L1110
Compounds: 142
抗乳腺癌化合物库
Cat.No: L2191
Compounds: 1939
线粒体靶向库
Cat.No: L5300
Compounds: 812
抗阿尔茨海默症化合物库
Cat.No: L9840
Compounds: 986
Cat. No. Product Name Form Specificity Of Inhibition
C0051 Penicillin-Streptomycin Solution (100×), Sterile

青霉素-链霉素双抗溶液(100×),灭菌

Solution in bottle
C0052 Penicillin-Streptomycin-Amphotericin B Solution (100×), Sterile

青霉素-链霉素-两性霉素B三抗溶液(100×),灭菌

Solution in bottle

TargetMol 试剂盒

青霉素-链霉素双抗溶液(100×),灭菌
Cat.No: C0051
青霉素-链霉素-两性霉素B三抗溶液(100×),灭菌
Cat.No: C0052
Cat. No. Product Name Target Signaling Pathways
T36523 Extracellular Death Factor

Programmed cell death in bacteria is dependent on a system of cell-to-cell communication termed quorum sensing. Extracellular death factor (EDF) is a linear pentapeptide that communicating cells produce and release, which upon reaching a sufficient concentration activates the cell death pathway in a subset of cells. It is sensitive to extreme pH, high temperatures, and other stressful conditions. At 2.5 ng/ml, EDF has been shown to facilitate mazEF-mediated cell death, significantly reducing pop...
T39849 Propargite

Parasite Microbiology/Virology
Propropgite 通过诱导 DNA 损伤来诱导 β 细胞坏死。它诱导 MIN6 细胞死亡的 IC50为 1 μM.。它可用于杀死螨虫。
T8982 RH01687

Others Others
RH01687 是可以保护胰腺 β 细胞免受内质网应激诱导的细胞死亡的化合物。它对糖尿病具有潜在的研究价值。
T11520 GW806742X

MLK; VEGFR Angiogenesis; MAPK; Tyrosine Kinase/Adaptors
GW806742X 是ATP 模拟物,是MLKL 抑制剂,可结合 MLKL 假激酶结构域,Kd 值为 9.3μM。它对VEGFR2的IC50为 2 nM,延缓 MLKL 膜移位并抑制坏死。
T5210 BAI1

Apoptosis; BCL Apoptosis
BAI1 是一种选择性凋亡因子BAX 变构抑制剂。它结合 BAX 并变构抑制其激活,具有潜力研究 BAX 依赖性细胞死亡介导的疾病。
T8320 J14

J-14

Reactive Oxygen Species Immunology/Inflammation; Metabolism; NF-κB
J14 是一种可逆的 sulfiredoxin 抑制剂,IC50=8.1 μM。它能够抑制sulfiredoxin 诱导氧化应激,使细胞内ROS 积累,导致细胞毒性和癌细胞死亡。
T8922 SRS11-92

AA9

Ferroptosis Apoptosis
SRS11-92 (AA9) 是一种铁死亡抑制剂和 Ferrostatin-1 的衍生物。它抑制 Erastin 诱导的 HT-1080 人纤维肉瘤细胞铁致细胞死亡,EC50为6 nM。
T5827 BI-6C9

Apoptosis; Others; Mitochondrial Metabolism Apoptosis; Metabolism; Others
BI-6C9 是一种高特异性的 BH3 相互作用结构域抑制剂,可阻止线粒体外膜电位和线粒体分裂,并保护细胞免受线粒体凋亡诱导因子释放和不依赖 caspase 的细胞死亡。
T22026 AGK7

Others; Sirtuin Chromatin/Epigenetic; DNA Damage/DNA Repair; Others
AGK7 是 sirtuin 2 (SIRT2) 抑制剂。它在体外和帕金森病果蝇模型中均能抑制多巴胺能细胞的凋亡。在帕金森病细胞模型中,它改善了 α-突触核蛋白毒性和修饰的包涵体形态
T10952 Dabuzalgron

达布扎琼,Ro 115-1240

Apoptosis; Adrenergic Receptor Apoptosis; GPCR/G Protein; Neuroscience
Dabuzalgron (Ro 115-1240) 是一种口服活性选择性 α-1A 肾上腺素受体激动剂,用于治疗尿失禁。它通过维持线粒体功能来预防多柔比星引起的心脏毒性。
T21678 3MB-PP1

PLK Cell Cycle/Checkpoint
3MB-PP1是嘌呤类似物,是一种 Polo 样激酶 1 (Plk1) 抑制剂。在表达类似物敏感的 Plk1 等位基因的细胞中,3MB-PP1 通过靶向 Plk1 阻断有丝分裂进程和细胞分裂。3MB-PP1 特异性抑制类似物敏感的 Ssn3 (Cdk8)。3MB-PP1 抑制 Leu93 突变 Zipper-interacting protein kinase(Leu93-ZIPK),IC50为2 μM。3MB-PP1 可用于细胞分裂和白色念珠菌 (Candida albicans) 菌丝形成的研究。
T36964 BML-259

CAY10554

CDK Cell Cycle/Checkpoint
BML-259 是 CDK5 和 CDK2 的抑制剂,IC50 分别为 64 和 98 nM。 BML-259 可用于癌症和神经退行性疾病治疗的研究。
T4517 L189

DNA; DNA/RNA Synthesis Cell Cycle/Checkpoint; DNA Damage/DNA Repair
L189 是一种人类 DNA 连接酶抑制剂,抑制 hLigI/III/IV,IC50值分别为5、9 和 5 μM。
T6500 Ferrostatin-1

Ferrostatin 1,Ferrostatin-1 (Fer-1)

Ferroptosis; Antifungal Apoptosis; Microbiology/Virology
Ferrostatin-1 (Fer-1) 是一种铁死亡抑制剂,具有强效性和选择性。Ferrostatin-1 有效抑制 Erastin 诱导的 HT-1080 细胞铁死亡 (EC50=60 nM)。Ferrostatin-1 还具抗氧化和抗真菌活性。
T1885 Siramesine hydrochloride

Lu 28-179 hydrochloride,西拉美新盐酸盐

Ferroptosis; Sigma receptor; lysosomal autophagy Apoptosis; Autophagy; GPCR/G Protein
Siramesine hydrochloride (Lu 28-179 hydrochloride) 是一种选择性 sigma-2 受体激动剂,可引发 Y 细胞的细胞死亡并在体内表现出有效的抗癌活性。Siramesine 对 sigma-2 受体具有亚纳摩尔亲和力,并且对 sigma-2 受体的选择性是 sigma-1 受体的 140 倍。
T11139 (E/Z)-BCI

NSC 150117

Apoptosis; Phosphatase Apoptosis; Metabolism
(E/Z)-BCI (NSC-150117) 是一种DUSP6抑制剂,可通过激活 Nrf2 信号和抑制 NF-κB 通路,减弱 LPS 诱导的巨噬细胞炎症和 ROS 生成,具有抗炎活性。
T21463 Temozolomide Acid

TMZA,3,4-二氢-3-甲基-4-氧代咪唑并[5,1-D]-1,2,3,5-四嗪-8-甲酰胺酸

Others Others
Temozolomide Acid (TMZA) 是 temozolomide (TMZ) 的代谢物。TMZ 在体外具有抗癌活性。TMZ 是一种口服烷化剂,用于治疗多形性胶质母细胞瘤 (GBM) 和星形细胞瘤。
T12472 Pifithrin-α, p-Nitro, Cyclic

PFN-α

p53 Apoptosis
Pifithrin-α, p-Nitro, Cyclic (PFN-α) 是 p53 的细胞渗透性和活性形式抑制剂。它对暴露于 Etoposide 的皮层神经元的保护作用比 Pifithrin-α 强一个数量级,ED50为30 nM。它也作为 p53 转录后的活性抑制剂。
T9083 TC11

CLT-003,1H-Isoindole-1,3(2H)-dione, 5-amino-2-[2,6-bis(1-methylethyl)phenyl]-TC11

BCL; Caspase; CDK Apoptosis; Cell Cycle/Checkpoint; Proteases/Proteasome
TC11 (1H-Isoindole-1,3(2H)-dione, 5-amino-2-[2,6-bis(1-methylethyl)phenyl]-TC11) 是一种有效的肿瘤细胞增殖抑制剂,并通过激活 caspase-3、8 和 9 诱导细胞凋亡。在长时间有丝分裂阻滞期间,它诱导 MCL1降解导致凋亡。它作为苯酞酰亚胺衍生物在结构上与免疫调节药物相关。
T12617L (R)​-​CR8

(R)-CR8,(R)-Isomer,(2R)-2-[[9-异丙基-6-[[[4-(2-吡啶基)苯基]甲基]氨基]-9H-嘌呤-2-基]氨基]-1-丁醇,CR8

Apoptosis; CDK Apoptosis; Cell Cycle/Checkpoint
(R)​-​CR8 ((R)-Isomer) 是 Roscovitine 类似物,是CDK1/2/5/7/9抑制剂。它作为一种分子胶降解剂来消耗细胞周期蛋白 K。它诱导细胞凋亡并具有神经保护作用。
T4620 Siramesine

西拉美新,Lu 28-179

Sigma receptor GPCR/G Protein
Siramesine (Lu 28-179) 是sigma-2受体激动剂,通过线粒体的不稳定溶酶体触发细胞死亡,有强大的抗癌活性。它对 sigma-2 受体具有亚纳摩尔亲和力,IC50为 0.12 nM。它对 sigma-2 受体的选择性是 sigma-1 受体的 140倍,IC50为 17 nM。
T12906 SI-2 hydrochloride

EPH 116 hydrochloride

Src Angiogenesis; Tyrosine Kinase/Adaptors
SI-2 hydrochloride (EPH 116 hydrochloride) 是 SRC-3 的抑制剂,诱导乳腺癌细胞死亡的 IC50 值为 3-20 nM。SI-2 hydrochloride 具有良好的药代动力学特征和改善的毒性,以及可接受的口服可用性。
T30582 BRD56491

BRD-56491,BRD 56491

Others Others
BRD56491 is a non-toxic reactive oxygen species (ROS) enhancer that strongly elevates markers of oxidative stress without causing cell death.
T6611 NSC697923

2-[(4-methylphenyl)sulfonyl]-5-nitrofuran

E1/E2/E3 Enzyme Ubiquitination
NSC-697923 (2-[(4-methylphenyl)sulfonyl]-5-nitrofuran), a potent inhibitor of UBE2N (ubiquitin-conjugating enzyme E2 N, Ubc13), exhibits its role in inducing cell death in neuroblastoma (NB) cells through two distinct mechanisms. In p53 wild-type NB cells, NSC-697923 promotes the nuclear importation of p53, thereby triggering cell death. Meanwhile, in p53 mutant NB cells, NSC-697923 activates the JNK-mediated apoptotic pathway, leading to cell death. Additionally, NSC-697923 inhibits DNA damage ...
T8468 CIL62

Caspase Apoptosis; Proteases/Proteasome
CIL62 是一种不依赖 caspase-3/7 的细胞死亡诱导剂。CIL62的作用机制是 Necrostatin-1 依赖性细胞死亡。
T12379 PD-1-IN-22

Others; PD-1/PD-L1 Apoptosis; Cell Cycle/Checkpoint; Immunology/Inflammation; Others
PD-1-IN-22 是一种有效的程序性细胞死亡 1 (PD-1)/程序性细胞死亡配体1 (PD-L1) 相互作用的抑制剂,IC50 为 92.3 nM。
T35994 Erastin2

35MEW28

Ferroptosis Apoptosis
Erastin2 是一种铁死亡诱导剂,通过与亲脂性自由基捕获抗氧化剂ferrostatin-1或铁螯合剂去铁胺(DFO)来诱导细胞死亡。
T8652 CASP3 Activator 1541

Caspase Apoptosis; Proteases/Proteasome
CASP3 Activator 1541 是 caspase-3 酶原形式的激活剂,可诱导细胞死亡。
T3146 BMS-202

PD1-PDL1 inhibitor 2,PD-1/PD-L1 inhibitor 2

Apoptosis; PD-1/PD-L1 Apoptosis; Cell Cycle/Checkpoint; Immunology/Inflammation
BMS-202 (PD1-PDL1 inhibitor 2) 是一种非肽类 PD-1/PD-L 复合物抑制剂,其 IC50为 18 nM,KD 为 8 μM。它与 PD-L1 直接结合并阻断人类 PD-1/PD-L 的相互作用,具有抗肿瘤活性。
T7008 Vacquinol-1

Vacquinol 1

JNK MAPK
Vacquinol-1 能够激活 MAPK 通路,是MKK4特异性激活剂。它可以诱导肝细胞癌细胞凋亡,在多形性胶质母细胞瘤小鼠模型中特异性诱导人胶质母细胞瘤细胞死亡、减缓肿瘤进展并延长生存期。
TP2205L DAPK Substrate Peptide acetate

DAPK Apoptosis
DAPK Substrate Peptide acetate 是一种死亡相关蛋白激酶 (DAPK, Km = 9 μM) 肽底物。
T5913 Sulbutiamine

舒布硫胺,Bisibuthiamine

Antioxidant oxidation-reduction
Sulbutiamine (Bisibuthiamine) 是合成的维生素 B1 类似物,可用于研究无力症。
T3953 Salermide

Apoptosis; Sirtuin Apoptosis; Chromatin/Epigenetic; DNA Damage/DNA Repair
Salermide 是一种 Sirt1 和 Sirt2 的抑制剂,可诱导强烈的癌症特异性细胞凋亡。
T14912 CD3254

Retinoid Receptor Metabolism
CD3254 是一种具有选择性和强效性的类视黄醇 X 受体 (RXR) 激动剂,可抑制伴有OGD/再氧合的神经元细胞死亡。
T1880 P7C3

Others Others
P7C3 是一种 aminopropyl carbazole 类化合物,具有口服活性,可透过血脑屏障,具有神经保护作用。它可用于神经退行性疾病,如帕金森病的研究。
T13540 alpha-Amanitin

α-Amatoxin,α-Amanitin

Others; ADC Cytotoxin Antibody-drug Conjugate/ADC Related; Others
alpha-Amanitin (α-Amanitin) 是鹅膏菌中致命的毒素,过肠肝循环和运输系统在体内起作用。alpha-Amanitin 可诱导细胞死亡,可用于合成 ADC。
T2020 RGW 611

Others Others
RGW 611 是一种能够增强辐射且诱导缺氧 V79-379A 细胞死亡的吗啉衍生物。
T9024 OUL35

NSC39047

Others; PARP Chromatin/Epigenetic; DNA Damage/DNA Repair; Others
OUL35 (NSC-39047) 是一种选择性 PARP-10 抑制剂和小分子 ARTD10 抑制剂,其 IC50值为 329 nM。
T10268 AGX51

Others Others
AGX51 是 DNA 结合蛋白抑制剂 (ID) 的拮抗剂。 AGX51 治疗导致泛 Id 降解、细胞周期停滞和细胞死亡。
T16540 Piperazine Erastin

Ferroptosis Apoptosis
Piperazine Erastin 是erastin 的类似物。它会导致一种铁依赖形式的非凋亡性细胞死亡,称为铁死亡。
T20797 NE-100 hydrochloride

NE100 Hydrochloride,NE 100 HCl,NE 100 Hydrochloride,NE-100 Hydrochloride,NE-100 HCl

Sigma receptor GPCR/G Protein
NE-100 hydrochloride (NE-100 HCl) 是选择性sigma-1 受体拮抗剂,IC50为 4.16 nM。它在体内具有抗精神病活性。它也能抑制内质网应激诱导的海马细胞死亡。
T65013 Cuprizone

Others Others
Cuprizone 是一种铜螯合剂。Cuprizone 可用于诱导小鼠精神分裂症。Cuprizone 可诱导少突胶质细胞死亡,诱导脱髓鞘反应。
T16699 PYZD-4409

Others; E1/E2/E3 Enzyme Others; Ubiquitination
PYZD-4409 是一种特异性 UBA1 抑制剂,IC50 为 20 μM。 PYZD-4409 在恶性细胞中诱导细胞死亡,并且对恶性细胞的细胞毒性优于对正常造血细胞的细胞毒性。
T8808L LYN-1604 dihydrochloride

LYN-1604 2HCl(2216753-86-3 free base)

Apoptosis; Autophagy Apoptosis; Autophagy
LYN-1604 2HCl 是一种有效的 UNC-51 样激酶 1 激活剂,EC50值为 18.94 nM。LYN-1604 可研究三阴性乳腺癌。
T16817 S-2474

Lipoxygenase; COX Immunology/Inflammation; Metabolism; Neuroscience
S-2474 是 COX-2 和 5-脂氧合酶的抑制剂 ,具有抗炎活性和神经保护活性,可抑制 Abeta(25 - 35) 和 Abeta(1 - 40) 诱导的细胞死亡。
TQ0318L ARRY 520 hydrochloride

KSP Cell Cycle/Checkpoint
ARRY 520 hydrochloride 是一种驱动蛋白纺锤体蛋白 (KSP) 抑制剂。它通过凋亡诱导细胞死亡,并具有有效的抗增殖活性。
T9004 TM2-115

Parasite Microbiology/Virology
TM2-115 是疟原虫组蛋白甲基转移酶的抑制剂,可导致疟原虫快速且不可逆的死亡。
T17004 TC-DAPK 6

DAPK Apoptosis
TC-DAPK 6 是死亡相关蛋白激酶 (DAPK) 的 ATP 竞争性抑制剂,对 DAPK1 和 DAPK3 的 IC50 分别为 69 和 225 nM。
T3525 PD150606

Cysteine Protease Proteases/Proteasome
PD150606 是一种具有选择性的非肽 calpain 抑制剂,具有神经保护活性,抑制 μ-calpains 和 m-calpains ,抑制红藻氨酸诱导的 Ca2+ 内流,干扰兴奋性毒性依赖性运动神经元死亡。
T0902 Ofloxacin

DL8280,菲宁达,Hoe-280,氧氟沙星,Floxin,Tarivid,Oxaldin

Topoisomerase; Antibacterial; Antibiotic DNA Damage/DNA Repair; Microbiology/Virology
Ofloxacin (Oxaldin) 是可抑制细菌DNA 旋转酶的一种氟喹诺酮类抗生素。

化合物

Extracellular Death Factor
Cat.No: T36523
Synonym:
Target:
Propargite
Cat.No: T39849
Synonym:
Target: Parasite
RH01687
Cat.No: T8982
Synonym:
Target: Others
GW806742X
Cat.No: T11520
Synonym:
Target: MLK, VEGFR
BAI1
Cat.No: T5210
Synonym:
Target: Apoptosis, BCL
J14
Cat.No: T8320
Synonym: J-14
Target: Reactive Oxygen Species
SRS11-92
Cat.No: T8922
Synonym: AA9
Target: Ferroptosis
BI-6C9
Cat.No: T5827
Synonym:
Target: Apoptosis, Others, Mitochondrial Metabolism
AGK7
Cat.No: T22026
Synonym:
Target: Others, Sirtuin
Dabuzalgron
Cat.No: T10952
Synonym: 达布扎琼,Ro 115-1240
Target: Apoptosis, Adrenergic Receptor
3MB-PP1
Cat.No: T21678
Synonym:
Target: PLK
BML-259
Cat.No: T36964
Synonym: CAY10554
Target: CDK
L189
Cat.No: T4517
Synonym:
Target: DNA, DNA/RNA Synthesis
Ferrostatin-1
Cat.No: T6500
Synonym: Ferrostatin 1,Ferrostatin-1 (Fer-1)
Target: Ferroptosis, Antifungal
Siramesine hydrochloride
Cat.No: T1885
Synonym: Lu 28-179 hydrochloride,西拉美新盐酸盐
Target: Ferroptosis, Sigma receptor, lysosomal autophagy
(E/Z)-BCI
Cat.No: T11139
Synonym: NSC 150117
Target: Apoptosis, Phosphatase
Temozolomide Acid
Cat.No: T21463
Synonym: TMZA,3,4-二氢-3-甲基-4-氧代咪唑并[5,1-D]-1,2,3,5-四嗪-8-甲酰胺酸
Target: Others
Pifithrin-α, p-Nitro, Cyclic
Cat.No: T12472
Synonym: PFN-α
Target: p53
TC11
Cat.No: T9083
Synonym: CLT-003,1H-Isoindole-1,3(2H)-dione, 5-amino-2-[2,6-bis(1-methylethyl)phenyl]-TC11
Target: BCL, Caspase, CDK
(R)​-​CR8
Cat.No: T12617L
Synonym: (R)-CR8,(R)-Isomer,(2R)-2-[[9-异丙基-6-[[[4-(2-吡啶基)苯基]甲基]氨基]-9H-嘌呤-2-基]氨基]-1-丁醇,CR8
Target: Apoptosis, CDK
Siramesine
Cat.No: T4620
Synonym: 西拉美新,Lu 28-179
Target: Sigma receptor
SI-2 hydrochloride
Cat.No: T12906
Synonym: EPH 116 hydrochloride
Target: Src
BRD56491
Cat.No: T30582
Synonym: BRD-56491,BRD 56491
Target: Others
NSC697923
Cat.No: T6611
Synonym: 2-[(4-methylphenyl)sulfonyl]-5-nitrofuran
Target: E1/E2/E3 Enzyme
CIL62
Cat.No: T8468
Synonym:
Target: Caspase
PD-1-IN-22
Cat.No: T12379
Synonym:
Target: Others, PD-1/PD-L1
Erastin2
Cat.No: T35994
Synonym: 35MEW28
Target: Ferroptosis
CASP3 Activator 1541
Cat.No: T8652
Synonym:
Target: Caspase
BMS-202
Cat.No: T3146
Synonym: PD1-PDL1 inhibitor 2,PD-1/PD-L1 inhibitor 2
Target: Apoptosis, PD-1/PD-L1
Vacquinol-1
Cat.No: T7008
Synonym: Vacquinol 1
Target: JNK
DAPK Substrate Peptide acetate
Cat.No: TP2205L
Synonym:
Target: DAPK
Sulbutiamine
Cat.No: T5913
Synonym: 舒布硫胺,Bisibuthiamine
Target: Antioxidant
Salermide
Cat.No: T3953
Synonym:
Target: Apoptosis, Sirtuin
CD3254
Cat.No: T14912
Synonym:
Target: Retinoid Receptor
P7C3
Cat.No: T1880
Synonym:
Target: Others
alpha-Amanitin
Cat.No: T13540
Synonym: α-Amatoxin,α-Amanitin
Target: Others, ADC Cytotoxin
RGW 611
Cat.No: T2020
Synonym:
Target: Others
OUL35
Cat.No: T9024
Synonym: NSC39047
Target: Others, PARP
AGX51
Cat.No: T10268
Synonym:
Target: Others
Piperazine Erastin
Cat.No: T16540
Synonym:
Target: Ferroptosis
NE-100 hydrochloride
Cat.No: T20797
Synonym: NE100 Hydrochloride,NE 100 HCl,NE 100 Hydrochloride,NE-100 Hydrochloride,NE-100 HCl
Target: Sigma receptor
Cuprizone
Cat.No: T65013
Synonym:
Target: Others
PYZD-4409
Cat.No: T16699
Synonym:
Target: Others, E1/E2/E3 Enzyme
LYN-1604 dihydrochloride
Cat.No: T8808L
Synonym: LYN-1604 2HCl(2216753-86-3 free base)
Target: Apoptosis, Autophagy
S-2474
Cat.No: T16817
Synonym:
Target: Lipoxygenase, COX
ARRY 520 hydrochloride
Cat.No: TQ0318L
Synonym:
Target: KSP
TM2-115
Cat.No: T9004
Synonym:
Target: Parasite
TC-DAPK 6
Cat.No: T17004
Synonym:
Target: DAPK
PD150606
Cat.No: T3525
Synonym:
Target: Cysteine Protease
Ofloxacin
Cat.No: T0902
Synonym: DL8280,菲宁达,Hoe-280,氧氟沙星,Floxin,Tarivid,Oxaldin
Target: Topoisomerase, Antibacterial, Antibiotic
Cat. No. Product Name Target Signaling Pathways
T4004 Concanavalin A

Apoptosis Apoptosis
Concanavalin A 是 Ca2+/Mn2+依赖性和甘露糖/葡萄糖结合植物凝集素。它能够促使程序性细胞死亡。
T2S0820 Karanjin

干华豆晶 4,水黄皮素

Apoptosis; AMPK Apoptosis; Chromatin/Epigenetic; PI3K/Akt/mTOR signaling
Karanjin 是干花豆中的主要活性呋喃黄酮醇成分,可通过细胞周期阻滞诱导癌细胞死亡,促进细胞凋亡,还通过提高AMPK 的方式诱导骨骼肌细胞 GLUT4 易位。
T6485 Embelin

NSC 91874,恩贝酸,恩贝酸/恩贝灵,Emberine,Embelic acid

Apoptosis; NF-κB; Lipoxygenase; IAP; Prostaglandin Receptor; Autophagy Apoptosis; Autophagy; GPCR/G Protein; Immunology/Inflammation; Metabolism; NF-κB
Embelin (Embelic acid) 是从日本 Ardisia 草药中分离出来的一种非肽类细胞渗透性XIAP 抑制剂,诱导口腔鳞癌细胞自噬和凋亡。它阻断 NF-kappaB 信号通路,从而抑制 NF-kappaB 调节的抗凋亡和转移基因产物。在高水平 XIAP 的前列腺癌细胞中抑制细胞生长,诱导凋亡,并激活 caspase-9。
TN6714 Geranylgeraniol

FT-0626663,Tetraprenol,CJ24095,CJ 24095,FT0626663,香叶基香叶醇,CJ-24095

Apoptosis Apoptosis
Geranylgeraniol (FT0626663) 是一种类异戊二烯,存在于水果、蔬菜和谷物中,包括大米。 Geranylgeraniol (FT0626663) 抑制生长并诱导各种肿瘤细胞的凋亡。 Geranylgeraniol (FT0626663) 保护单核细胞免受他汀类药物诱导的细胞毒性并抑制分枝杆菌的生长。
T4S0290 Araloside A

Chikusetsusaponin IV,竹节参皂苷IV

RAAS; Fas/FasL Apoptosis; Endocrinology/Hormones
Araloside A (Chikusetsusaponin IV) 是竹节参中的一种成分,对肾素renin 具有低抑制活性(IC50:77.4 μM)。
T21936 M50054

2,2′-亚甲基双(1,3-环己二酮)

Caspase Apoptosis; Proteases/Proteasome
M50054 是一种有效的细胞凋亡抑制剂,可用于研究抗 Fas 抗体引起的肝炎和化疗引起的脱发。它抑制 Etoposide 诱导的 U937 细胞 caspase-3 活化,IC50为 79 μg/mL。
T3S1775 Tectochrysin

NSC 80687,Techtochrysine,Techtochrysin,柚木柯因

NF-κB; STAT JAK/STAT signaling; NF-κB; Stem Cells
Tectochrysin (Techtochrysine) 是Alpinia oxyphylla 的主要黄酮类化合物之一,能够抑制NF-κB 活性。
TN1600 Eclalbasaponin I

Others Others
Eclalbasaponin I 分离自鳢肠中,具有抗肿瘤作用,能够抑制肝癌细胞 smmc-7721 的增殖(IC50:111.1703 μg/ml)。
T3914 Saikosaponin C

柴胡皂苷C,柴胡皂苷 C

Beta Amyloid; Caspase Apoptosis; Neuroscience; Proteases/Proteasome
Saikosaponin C 是一种柴胡中的活性成分,能够抑制 Aβ1-40 和 Aβ1-42 的释放,抑制异常 tau 蛋白的磷酸化,但对 BACE1 的活性和表达无作用。它在阿尔滋海默症中主要靶作用于amyloid beta 和tau 蛋白。
T0968 Paclitaxel

Taxol,紫杉醇,NSC 125973

Apoptosis; Microtubule Associated; Autophagy; ADC Cytotoxin Antibody-drug Conjugate/ADC Related; Apoptosis; Autophagy; Cytoskeletal Signaling
Paclitaxel (Taxol) 属于天然产物,是一种微管聚合物稳定剂。Paclitaxel 具有抗肿瘤活性;通过诱导有丝分裂停滞、细胞凋亡、细胞自噬等,导致细胞死亡。
T15027 Cyclopiazonic acid

环匹阿尼酸,环二氮酸

Calcium Channel Membrane transporter/Ion channel; Metabolism
Cyclopiazonic acid 是一种神经毒性次级代谢产物 (SM),源于A. flavus,是一种纳摩尔内质网钙 ATP 酶抑制剂 (Ca2+ATPase; SERCA),是植物细胞死亡的有效诱导剂。
T5300 Ammonium formate

甲酸铵,Formic acid ammonium salt

Others Others
Ammonium formate (Formic acid ammonium salt) 是最简单的羧酸。它通过抑制细胞色素氧化酶活性(电子传递链的末端电子受体)来负责代谢性酸中毒和破坏线粒体电子传递和能量产生。
T6S0654 Isocorynoxeine

7-Isocorynoxeine,异去氢钩藤碱

5-HT Receptor GPCR/G Protein; Neuroscience
Isocorynoxeine (7-Isocorynoxeine) 是钩藤中的一种生物碱,剂量依赖性抑制5-HT2A 受体介导的电流反应,IC50为 72.4 μM。
TN6120 Nauclefine

Parvine

PDE Metabolism
Nauclefine (Parvine) 是一种植物吲哚生物碱天然产物,可通过 PDE3A-SLFN12 依赖性死亡途径诱导多种癌细胞的凋亡。 Nauclefine 结合 PDE3A 但不抑制 PDE3A 的磷酸二酯酶活性。
TN1038 Galgravin

Apoptosis Apoptosis
Galgravin 是望春花中的一种天然产物,具有抗炎和体外细胞毒活性,能诱导白血病细胞凋亡。
TN2097 Pomolic acid

坡模酸

Apoptosis; Caspase; HIV Protease; AMPK Apoptosis; Chromatin/Epigenetic; Microbiology/Virology; PI3K/Akt/mTOR signaling; Proteases/Proteasome
Pomolic acid 是从野鸦椿中分离出来的一种五环三萜烯。它抑制肿瘤细胞的生长,诱导细胞凋亡,有用于前列腺癌的潜力。
T5S0281 Tubuloside A

NOS Immunology/Inflammation
Tubuloside A 是一种苯乙醇苷,具有抗氧化活性和保肝活性。
T2S0886 Terrestrosin D

Apoptosis; Others Apoptosis; Others
Terrestrosin D 是从刺蒺藜中提取得到一种的甾体皂苷,可诱导细胞周期阻滞和癌细胞凋亡,具有抗血管生成的活性。
TN1376 α-Solanine

alpha-Solanine

Apoptosis; NF-κB Apoptosis; NF-κB
α-Solanine (alpha-Solanine) 是从马铃薯中提取得到的生物碱,具有抗癌抗肿瘤活性,通过抑制NF-κB通路减弱软骨细胞焦亡。α-Solanine 抑制神经胶质瘤细胞的增殖和迁移,促进了胶质瘤细胞的凋亡。
TN1956 Mulberrofuran G

Phosphatase; HBV; Glucosidase Metabolism; Microbiology/Virology
Mulberrofuran G分离自自 Morus alba L.,具有抗乙型肝炎病毒活性,可保护缺血损伤诱导的细胞死亡。Mulberrofuran G 是一种 PTP1B 和 α-葡萄糖苷酶的双重抑制剂,可用于研究阿尔茨海默症。
T6228 Irinotecan

CPT-11,Topotecin,伊立替康,(+)-Irinotecan

Topoisomerase; Autophagy Autophagy; DNA Damage/DNA Repair
Irinotecan (CPT-11) 是喜树碱的衍生物,是一种 DNA 拓扑异构酶 I (Topo I) 的抑制剂。Irinotecan 通过与 Topo I 复合物结合来阻止 DNA 链的重新连接,并导致双链 DNA 断裂和细胞死亡,具有抗肿瘤活性。
TN1543 Cynaropicrin

HCV Protease; NF-κB; Microtubule Associated Cytoskeletal Signaling; Microbiology/Virology; NF-κB; Proteases/Proteasome
Cynaropicrin 是一种存在于朝鲜蓟 (Cynara scolymus) 中倍半萜内酯,具有抗丙型肝炎活性和抗锥虫活性活性,抑制NF-κB活化。 Cynaropicrin 破坏微管蛋白和 c-Myc 相关信号传导,并诱导多发性骨髓瘤中的 parthanatos 型细胞死亡。
T22455 Vindesine sulfate

DVA,Desacetylvinblastine amide,硫酸长春地辛,DAVA,Desacetyl Vinblastine amide,VDS

Others Others
Vindesine sulfate (Desacetyl Vinblastine amide) 是一种长春花生物碱,它是长春碱的合成衍生物,与有丝分裂纺锤体的微管蛋白结合,导致微管结晶和有丝分裂停滞或细胞死亡。
TN2085 Piperlonguminine

Anti-infection; Antibacterial; Antifungal Microbiology/Virology
Piperlonguminine 是一种从 Piper 中分离出的生物碱酰胺。它具有多种生物活性,如神经保护、抗炎、抗肿瘤、抗血小板、抗黑素生成、抗真菌和抗菌活性。
T3395 Timosaponin AIII

Filiferin B,知母皂苷 A-III,AneMarsaponin A3,Timosaponin A3

AChE; mTOR Neuroscience; PI3K/Akt/mTOR signaling
Timosaponin AIII (Timosaponin A3) 是一种乙酰胆碱酯酶活性抑制剂,其IC50=35.4 μM。
TN1721 Gypenoside L

ERK; p38 MAPK; Calcium Channel; NF-κB; ROS Immunology/Inflammation; MAPK; Membrane transporter/Ion channel; Metabolism; NF-κB
Gypenoside L 是存在于绞股蓝中的一种皂苷,可增加 SA-β-半乳糖苷酶活性,促进衰老相关分泌细胞因子的产生。它还可以激活p38和ERK MAPK 通路和NF-κB 通路以诱导衰老,具有抗肿瘤和抗炎活性。
T4558 Trioxsalen

三甲沙林,Trimethylpsoralen,Trioxysalen,Trisoralen

DNA Alkylator/Crosslinker; DHFR Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism
Trioxsalen (Trioxysalen) 是一种呋喃香豆素和补骨脂素衍生物,与 UV-A 一起用于光疗治疗白癜风和手部湿疹。它是一种光化学 DNA 交联剂,可用于激光激活定位的基因组链间交联可视化。
T5059 L-Tartaric acid

L-酒石酸,L(+)-Tartaric acid,(2R,3R)-(+)-Tartaric acid

Antioxidant; Endogenous Metabolite Metabolism; oxidation-reduction
L-Tartaric acid ((2R,3R)-(+)-Tartaric acid) 是内源性代谢产物的一种。
T7032 Eupatorin

Others; P450 Metabolism; Others
Eupatorin 是天然存在的黄酮,可捕获 G2-M 细胞周期,激活多个 caspase、细胞色素 C 的释放、多聚 (ADP-核糖) 聚合酶的裂解,促使凋亡细胞死亡。
T3S0645 N-trans-Feruloyltyramine

Feruloyltyramine,N-Feruloyltyramine,Moupinamide,N-反式阿魏酰酪胺

Others; COX Immunology/Inflammation; Neuroscience; Others
N-trans-Feruloyltyramine (Feruloyltyramine) 是从大麻中分离得到的一种生物碱,是COX1和COX2的抑制剂,具有抗氧化和抗炎活性。
T3030 L-Sophoridine

L-槐定碱,Sophoridine,Matridin-15-one

Others Others
L-Sophoridine (Matridin-15-one) 一种从药用植物中提取的天然产物,具有多种药理作用,包括抗Y 作用,可在体外和体内选择性诱导多种人体Y 细胞凋亡;然而,其作用机制需要进一步阐述。
T5062 rel-(2R,3S)-2,3-Dihydroxysuccinic acid hydrate

meso-Tartaric acid monohydrate,内消旋酒石酸 一水合物

Antioxidant; Endogenous Metabolite Metabolism; oxidation-reduction
rel-(2R,3S)-2,3-Dihydroxysuccinic acid hydrate (meso-Tartaric acid monohydrate) 是内源性代谢产物的一种。
T2795 Amygdalin

苦杏仁苷,Laetrile

Others Others
Amygdalin (Laetrile) 是一种植物葡萄糖苷,分离自蔷薇果实的果核中,如杏,桃,杏仁,樱桃和李子。
T5S0890 Oleandrin

Neriostene,Folinerin,Foliandrin,欧夹竹桃苷

Apoptosis; ATPase; Potassium Channel; Sodium Channel Apoptosis; Membrane transporter/Ion channel
Oleandrin (Folinerin) 是夹竹桃属中的一种类固醇,可抑制Na+/K+-ATPase 活性,IC50为 620 nM。
T4S1335 Daphnoretin

Dephnoretin,西瑞香素,Thymelol

Influenza Virus; Caspase; PKC Apoptosis; Chromatin/Epigenetic; Cytoskeletal Signaling; Microbiology/Virology; Proteases/Proteasome
Daphnoretin (Thymelol) 是从了哥王中提取得到的一种天然产物,具有抗癌和抗病毒活性。它通过在 G2/M 期连续阻断细胞并激活 caspase-3 通路导致 HOS 细胞死亡。
T2823 Crocin

西红花苷,藏红花,Gardenia Yellow,Alpha-Crocin,藏红花素

Others Others
Crocin (Gardenia Yellow) 是从Crocus sativus 柱头中分离出的主要成分,是一种营养保健品,具有抗炎,抗癌,抗抑郁和抗惊厥等强大的药理作用。
T26288 Clovamide

trans-Clovamide,N-trans-Caffeoy-L-dopa

Apoptosis; Influenza Virus; ROS; Antibacterial Apoptosis; Immunology/Inflammation; Microbiology/Virology
Clovamide (trans-Clovamide) 是一种天然存在的咖啡酰结合物,具有抗菌、抗炎、抗氧化和神经保护作用。它是一种极好的活性氧和氧自由基清除剂。
TN1244 3'-Demethylnobiletin

LDL; NF-κB; Integrin; Lipoxygenase; DNA/RNA Synthesis Cell Cycle/Checkpoint; Cytoskeletal Signaling; DNA Damage/DNA Repair; Metabolism; NF-κB
3'-Demethylnobiletin 是样一种存在于柑橘类水果中的多甲氧基黄酮类化合物,是一种 Nobiletin 的衍生物。N 其中 obiletin 能够调节 Src,FAK 和 STAT3 信号传导来抗肿瘤,并能够抑制肿瘤血管生成。
T6S0659 Rhynchophylline

钩藤碱,Rhynchophyllin,Rhyncophylline,Mitrinermine,Mitrinermin

Calcium Channel; NF-κB Membrane transporter/Ion channel; Metabolism; NF-κB
Rhynchophylline (Mitrinermine) 是一种生物碱类化合物,从钩藤中分离得到,具有很高的生物活性,被广泛用于抗炎、神经保护等方面的研究。
T6S1784 Brazilin

Natural Red 24,巴西苏木素;苏枋精,Braziletto,Brasilin,Superbresiline,巴西苏木素

Apoptosis; Others; AMPK; Autophagy Apoptosis; Autophagy; Chromatin/Epigenetic; Others; PI3K/Akt/mTOR signaling
Brazilin (Braziletto) 是来自几种热带硬木的心材的一种红色染料前体,有软骨保护和抗炎活性。它抑制细胞增殖,促进细胞凋亡并通过 AMPK/mTOR 途径诱导自噬。
T1104 Paromomycin Sulfate

Aminosidine sulfate,Paromomycin sulfate salt,硫酸巴龙霉素,巴龙霉素硫酸盐

Antibacterial; Antibiotic; Parasite Microbiology/Virology
Paromomycin Sulfate (Aminosidine sulfate) 是一种广谱氨基糖苷类抗生素 ,是具有杀螨杀菌作用的新霉素衍生物。它通过与细菌 30S 核糖体 A 位点的 RNA 寡核苷酸特异性结合,使 mRNA 的翻译提前终止,并抑制蛋白质合成。它可研究细菌和寄生虫感染。
T3895 Polyphyllin I

重楼皂苷I,重楼皂甙

Apoptosis; Akt; JNK; PDK; mTOR; Autophagy Apoptosis; Autophagy; Cytoskeletal Signaling; MAPK; PI3K/Akt/mTOR signaling
Polyphyllin I 是从七叶一枝花中提取的生物活性成分,具有很强的抗肿瘤活性。它是 JNK 信号通路的激活剂,也是 PDK1/Akt/mTOR 信号传导的抑制剂。它诱导自噬,G2/M 期阻滞和细胞凋亡。
T4S1615 Sanggenon C

桑根酮C,桑根酮 C,Sanggenone C

NF-κB NF-κB
Sanggenon C (Sanggenone C) 是一种从桑属的根皮中分离得到的黄烷酮 Diels-Alder 加合物化合物。它可抑制NF-κB 活性,抑制 RAW264.7 细胞中诱导型一氧化氮合酶的表达,以及肿瘤坏死因子-α 刺激的细胞粘附和血管细胞粘附分子-1 的表达。 它具有抗氧化和抗炎作用,也有抑制胰脂肪酶作用。
T7033 Rosmanol

Antioxidant; COX Immunology/Inflammation; Neuroscience; oxidation-reduction
Rosmanol 能够显著抑制脂多糖诱导的 INOS、COX-2 的表达,抑制低密度脂蛋白的氧化,并具有抗炎作用。
TN6926 Paeonoside

Others Others
Paeonoside 发现与P. suffruticosa 中,具有生物活性,可以促进成骨细胞分化过程中的伤口愈合和迁移。Paeonoside 具有一定的抗糖尿病活性,可防止脓毒症和败血症引起的死亡。Paeonoside 对 MC3T3-E1细胞的前成骨细胞没有细胞毒性作用,以剂量依赖性的方式显著恢复伤口区域并促进细胞迁移和促进碱性磷酸酶(ALP)染色及其活性。
T0486L Irinotecan Hydrochloride

盐酸伊立替康,伊立替康盐酸盐,Camptothecin 11 hydrochloride,CPT-11 hydrochloride

Topoisomerase; Autophagy Autophagy; DNA Damage/DNA Repair
Irinotecan Hydrochloride (CPT-11 hydrochloride) 是喜树碱半合成衍生物的盐酸盐,是一种拓扑异构酶 I 抑制剂,可研究结肠癌和直肠癌。
T4752 1-Aminocyclopropane-1-carboxylic acid

1-Aminocyclopropanecarboxylic acid,1-氨基环丙烷羧酸,1-Amino-1-carboxycyclopropane,ACC

Endogenous Metabolite; NMDAR Metabolism; Neuroscience
1-Aminocyclopropane-1-carboxylic acid (ACC) 是内源性代谢产物的一种。
T6S1141 Ganoderic acid A

灵芝酸 A,灵芝酸A

Apoptosis; NF-κB; Endogenous Metabolite; Autophagy Apoptosis; Autophagy; Metabolism; NF-κB
Ganoderic acid A 能够抑制 JAK-STAT3信号通路,也能抑制细胞增殖,存活率和 ROS。 它对人骨肉瘤 HOS 和MG-63细胞具有增殖抑制、凋亡和侵袭抑制作用。
T3339 Sophoridine

5-Epidihydrosophocarpine,槐定碱,Dihydro-5-episophocarpine

Apoptosis; Topoisomerase Apoptosis; DNA Damage/DNA Repair
Sophoridine (Dihydro-5-episophocarpine) 是一种从豆科植物槐豆斜生植物的叶子中分离出来的喹喔啉生物碱。它是胰腺癌的候选药物,诱导细胞凋亡。
TN1831 Macranthoside A

Kalopanaxsaponin H

Antioxidant oxidation-reduction
Macranthoside A (Kalopanaxsaponin H) 是一种从地黄中提取的三萜糖苷,属于环烯醚萜类化合。Macranthoside A 具有抗炎、抗氧化、抗菌和神经保护活性,抑制促炎细胞因子的产生和抑制炎症信号通路的激活,有助于中和有害的自由基,保护细胞免受氧化损伤,可以促进神经元的存活和生长,并防止氧化应激或神经毒性化合物引起的神经元细胞死亡,具有治疗神经退行性疾病、心血管疾病和肝损伤的潜力。
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天然产物

Concanavalin A
Cat.No: T4004
Synonym:
Target: Apoptosis
Karanjin
Cat.No: T2S0820
Synonym: 干华豆晶 4,水黄皮素
Target: Apoptosis, AMPK
Embelin
Cat.No: T6485
Synonym: NSC 91874,恩贝酸,恩贝酸/恩贝灵,Emberine,Embelic acid
Target: Apoptosis, NF-κB, Lipoxygenase, IAP, Prostaglandin Receptor, Autophagy
Geranylgeraniol
Cat.No: TN6714
Synonym: FT-0626663,Tetraprenol,CJ24095,CJ 24095,FT0626663,香叶基香叶醇,CJ-24095
Target: Apoptosis
Araloside A
Cat.No: T4S0290
Synonym: Chikusetsusaponin IV,竹节参皂苷IV
Target: RAAS, Fas/FasL
M50054
Cat.No: T21936
Synonym: 2,2′-亚甲基双(1,3-环己二酮)
Target: Caspase
Tectochrysin
Cat.No: T3S1775
Synonym: NSC 80687,Techtochrysine,Techtochrysin,柚木柯因
Target: NF-κB, STAT
Eclalbasaponin I
Cat.No: TN1600
Synonym:
Target: Others
Saikosaponin C
Cat.No: T3914
Synonym: 柴胡皂苷C,柴胡皂苷 C
Target: Beta Amyloid, Caspase
Paclitaxel
Cat.No: T0968
Synonym: Taxol,紫杉醇,NSC 125973
Target: Apoptosis, Microtubule Associated, Autophagy, ADC Cytotoxin
Cyclopiazonic acid
Cat.No: T15027
Synonym: 环匹阿尼酸,环二氮酸
Target: Calcium Channel
Ammonium formate
Cat.No: T5300
Synonym: 甲酸铵,Formic acid ammonium salt
Target: Others
Isocorynoxeine
Cat.No: T6S0654
Synonym: 7-Isocorynoxeine,异去氢钩藤碱
Target: 5-HT Receptor
Nauclefine
Cat.No: TN6120
Synonym: Parvine
Target: PDE
Galgravin
Cat.No: TN1038
Synonym:
Target: Apoptosis
Pomolic acid
Cat.No: TN2097
Synonym: 坡模酸
Target: Apoptosis, Caspase, HIV Protease, AMPK
Tubuloside A
Cat.No: T5S0281
Synonym:
Target: NOS
Terrestrosin D
Cat.No: T2S0886
Synonym:
Target: Apoptosis, Others
α-Solanine
Cat.No: TN1376
Synonym: alpha-Solanine
Target: Apoptosis, NF-κB
Mulberrofuran G
Cat.No: TN1956
Synonym:
Target: Phosphatase, HBV, Glucosidase
Irinotecan
Cat.No: T6228
Synonym: CPT-11,Topotecin,伊立替康,(+)-Irinotecan
Target: Topoisomerase, Autophagy
Cynaropicrin
Cat.No: TN1543
Synonym:
Target: HCV Protease, NF-κB, Microtubule Associated
Vindesine sulfate
Cat.No: T22455
Synonym: DVA,Desacetylvinblastine amide,硫酸长春地辛,DAVA,Desacetyl Vinblastine amide,VDS
Target: Others
Piperlonguminine
Cat.No: TN2085
Synonym:
Target: Anti-infection, Antibacterial, Antifungal
Timosaponin AIII
Cat.No: T3395
Synonym: Filiferin B,知母皂苷 A-III,AneMarsaponin A3,Timosaponin A3
Target: AChE, mTOR
Gypenoside L
Cat.No: TN1721
Synonym:
Target: ERK, p38 MAPK, Calcium Channel, NF-κB, ROS
Trioxsalen
Cat.No: T4558
Synonym: 三甲沙林,Trimethylpsoralen,Trioxysalen,Trisoralen
Target: DNA Alkylator/Crosslinker, DHFR
L-Tartaric acid
Cat.No: T5059
Synonym: L-酒石酸,L(+)-Tartaric acid,(2R,3R)-(+)-Tartaric acid
Target: Antioxidant, Endogenous Metabolite
Eupatorin
Cat.No: T7032
Synonym:
Target: Others, P450
N-trans-Feruloyltyramine
Cat.No: T3S0645
Synonym: Feruloyltyramine,N-Feruloyltyramine,Moupinamide,N-反式阿魏酰酪胺
Target: Others, COX
L-Sophoridine
Cat.No: T3030
Synonym: L-槐定碱,Sophoridine,Matridin-15-one
Target: Others
rel-(2R,3S)-2,3-Dihydroxysuccinic acid hydrate
Cat.No: T5062
Synonym: meso-Tartaric acid monohydrate,内消旋酒石酸 一水合物
Target: Antioxidant, Endogenous Metabolite
Amygdalin
Cat.No: T2795
Synonym: 苦杏仁苷,Laetrile
Target: Others
Oleandrin
Cat.No: T5S0890
Synonym: Neriostene,Folinerin,Foliandrin,欧夹竹桃苷
Target: Apoptosis, ATPase, Potassium Channel, Sodium Channel
Daphnoretin
Cat.No: T4S1335
Synonym: Dephnoretin,西瑞香素,Thymelol
Target: Influenza Virus, Caspase, PKC
Crocin
Cat.No: T2823
Synonym: 西红花苷,藏红花,Gardenia Yellow,Alpha-Crocin,藏红花素
Target: Others
Clovamide
Cat.No: T26288
Synonym: trans-Clovamide,N-trans-Caffeoy-L-dopa
Target: Apoptosis, Influenza Virus, ROS, Antibacterial
3'-Demethylnobiletin
Cat.No: TN1244
Synonym:
Target: LDL, NF-κB, Integrin, Lipoxygenase, DNA/RNA Synthesis
Rhynchophylline
Cat.No: T6S0659
Synonym: 钩藤碱,Rhynchophyllin,Rhyncophylline,Mitrinermine,Mitrinermin
Target: Calcium Channel, NF-κB
Brazilin
Cat.No: T6S1784
Synonym: Natural Red 24,巴西苏木素;苏枋精,Braziletto,Brasilin,Superbresiline,巴西苏木素
Target: Apoptosis, Others, AMPK, Autophagy
Paromomycin Sulfate
Cat.No: T1104
Synonym: Aminosidine sulfate,Paromomycin sulfate salt,硫酸巴龙霉素,巴龙霉素硫酸盐
Target: Antibacterial, Antibiotic, Parasite
Polyphyllin I
Cat.No: T3895
Synonym: 重楼皂苷I,重楼皂甙
Target: Apoptosis, Akt, JNK, PDK, mTOR, Autophagy
Sanggenon C
Cat.No: T4S1615
Synonym: 桑根酮C,桑根酮 C,Sanggenone C
Target: NF-κB
Rosmanol
Cat.No: T7033
Synonym:
Target: Antioxidant, COX
Paeonoside
Cat.No: TN6926
Synonym:
Target: Others
Irinotecan Hydrochloride
Cat.No: T0486L
Synonym: 盐酸伊立替康,伊立替康盐酸盐,Camptothecin 11 hydrochloride,CPT-11 hydrochloride
Target: Topoisomerase, Autophagy
1-Aminocyclopropane-1-carboxylic acid
Cat.No: T4752
Synonym: 1-Aminocyclopropanecarboxylic acid,1-氨基环丙烷羧酸,1-Amino-1-carboxycyclopropane,ACC
Target: Endogenous Metabolite, NMDAR
Ganoderic acid A
Cat.No: T6S1141
Synonym: 灵芝酸 A,灵芝酸A
Target: Apoptosis, NF-κB, Endogenous Metabolite, Autophagy
Sophoridine
Cat.No: T3339
Synonym: 5-Epidihydrosophocarpine,槐定碱,Dihydro-5-episophocarpine
Target: Apoptosis, Topoisomerase
Macranthoside A
Cat.No: TN1831
Synonym: Kalopanaxsaponin H
Target: Antioxidant
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Cat. No. Product Name Species Expression System
TMPY-05815 PD-1 Protein, Canine, Recombinant (His & Avi), Biotinylated

programmed cell death 1

Canine HEK293 Cells
PD-1 Protein, Canine, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 19.41 kDa and the accession number is A0A090BAM7.
TMPY-05260 PD-1 Protein, Cynomolgus, Recombinant (His)

programmed cell death 1

Cynomolgus HEK293 Cells
PD-1 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.4 kDa and the accession number is B0LAJ3.
TMPY-04342 PD-1 Protein, Canine, Recombinant (His)

programmed cell death 1

Canine HEK293 Cells
PD-1 Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.7 kDa and the accession number is XP_022265285.1.
TMPY-05395 PD-1 Protein, Mouse, Recombinant (hFc)

Ly101,PD-1,programmed cell death 1,Pdc1

Mouse HEK293 Cells
PD-1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 42.9 kDa and the accession number is Q02242.
TMPY-00996 PD-1 Protein, Mouse, Recombinant (His)

programmed cell death 1,Pdc1,Ly101,PD-1

Mouse HEK293 Cells
PD-1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.6 kDa and the accession number is Q02242.
TMPY-04898 PD-1 Protein, Human, Recombinant (hFc)

PD1,programmed cell death 1,PD-1,hPD-l,hSLE1,CD279,...

Human HEK293 Cells
PD-1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 42.7 kDa and the accession number is A0A0M3M0G7.
TMPY-00897 PD-1 Protein, Human, Recombinant (His)

PD1,hPD-l,hPD-1,CD279,programmed cell death 1,hSLE1...

Human HEK293 Cells
PD-1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.4 kDa and the accession number is A0A0M3M0G7.
TMPY-05079 PD-1 Protein, Human, Recombinant (mFc)

PD-1,SLEB2,hSLE1,CD279,programmed cell death 1,hPD-...

Human HEK293 Cells
PD-1 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 42.3 kDa and the accession number is A0A0M3M0G7.
TMPY-05827 PD-L2 Protein, Human, Recombinant (mFc)

PDCD1L2,bA574F11.2,Btdc,B7-DC,PD-L2,programmed cell deat...

Human HEK293 Cells
PD-L2 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 48.93 kDa and the accession number is Q9BQ51-1.
TMPY-04957 PD-L2 Protein, Human, Recombinant (His), Biotinylated

B7DC,Btdc,B7-DC,bA574F11.2,PDL2,programmed cell death

Human HEK293 Cells
PD-L2 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24 kDa and the accession number is Q9BQ51-1.
TMPY-04346 PD-L2 Protein, Human, Recombinant (His)

PD-L2,B7-DC,CD273,Btdc,PDCD1L2,B7DC,PDL2,programmed cell

Human HEK293 Cells
PD-L2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24 kDa and the accession number is Q9BQ51-1.
TMPY-00253 PD-1 Protein, Cynomolgus, Recombinant (hFc)

programmed cell death 1

Cynomolgus HEK293 Cells
PD-1 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 42.7 kDa and the accession number is B0LAJ3.
TMPY-03717 PD-1 Protein, Rat, Recombinant (hFc)

programmed cell death 1

Rat HEK293 Cells
PD-1 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 43.2 kDa and the accession number is A6JR44.
TMPY-00250 PD-1 Protein, Rhesus, Recombinant (His)

programmed cell death 1

Rhesus HEK293 Cells
PD-1 Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.3 kDa and the accession number is A0A8J8XRF6.
TMPY-00633 PD-1 Protein, Rhesus, Recombinant (hFc)

programmed cell death 1

Rhesus HEK293 Cells
PD-1 Protein, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 42.7 kDa and the accession number is A0A8J8XRF6.
TMPJ-01059 CRADD Protein, Human, Recombinant

Caspase and RIP Adapter with Death Domain,RAIDD,RIP...

Human E. coli
Death Domain-Containing Protein CRADD (CRADD) is widely expressed in most tissues, with particularly high expression in the adult heart, testis, liver, skeletal muscle, fetal liver, and kidney. CRADD contains one CARD domain that mediates the interaction with caspase-2, and one death domain involved in the binding of RIP protein. CRADD functions as an apoptotic adaptor molecule specific for caspase-2 and FASL/TNF receptor-interacting protein RIP. CRADD induces cell apoptosis/cell death in numero...
TMPY-00047 Dengue virus DENV-2 (Strain New Guinea C) Capsid protein/DENV-C Protein (His)

death-domain associated protein

DENV E. coli
Dengue virus DENV-2 (Strain New Guinea C) Capsid protein/DENV-C Protein (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 14 kDa and the accession number is W0GCK5.
TMPY-04341 PD-1 Protein, Rat, Recombinant (His)

programmed cell death 1

Rat HEK293 Cells
PD-1 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.7 kDa and the accession number is A6JR44.
TMPY-00233 PD-1 Protein, Canine, Recombinant (hFc)

programmed cell death 1

Canine HEK293 Cells
PD-1 Protein, Canine, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 43 kDa and the accession number is XP_543338.3.
TMPY-05295 PD-1 Protein, Cynomolgus, Recombinant (hFc & Avi), Biotinylated

programmed cell death 1

Cynomolgus HEK293 Cells
PD-1 Protein, Cynomolgus, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 44.5 kDa and the accession number is B0LAJ3.
TMPY-03834 Fas/CD95 Protein, Cynomolgus, Recombinant (hFc)

Fas cell surface death receptor

Cynomolgus HEK293 Cells
Fas/CD95 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 43.8 kDa and the accession number is F6V1W6.
TMPY-04282 Fas/CD95 Protein, Rat, Recombinant (hFc)

Fas cell surface death receptor

Rat HEK293 Cells
Fas/CD95 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 43.7 kDa and the accession number is A6I127.
TMPY-04223 PD-L2 Protein, Rat, Recombinant (hFc)

programmed cell death 1 ligand 2

Rat HEK293 Cells
PD-L2 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.2 kDa and the accession number is D4AAV6.
TMPY-03738 PD-L2 Protein, Cynomolgus, Recombinant (His)

programmed cell death 1 ligand 2

Cynomolgus HEK293 Cells
PD-L2 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24 kDa and the accession number is A4GW30.
TMPY-02057 Fas/CD95 Protein, Rat, Recombinant (His)

Fas cell surface death receptor

Rat HEK293 Cells
Fas/CD95 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 18 kDa and the accession number is A6I127.
TMPY-00632 Fas/CD95 Protein, Cynomolgus, Recombinant

Fas cell surface death receptor

Cynomolgus HEK293 Cells
Fas/CD95 Protein, Cynomolgus, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 17.6 kDa and the accession number is F6V1W6.
TMPY-06819 PD-L2 Protein, Rhesus, Recombinant (hFc)

programmed cell death 1 ligand 2

Rhesus HEK293 Cells
PD-L2 Protein, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.6 kDa and the accession number is A4GW30.
TMPY-03404 PD-L2 Protein, Cynomolgus, Recombinant (hFc)

programmed cell death 1 ligand 2

Cynomolgus HEK293 Cells
PD-L2 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.6 kDa and the accession number is A4GW30.
TMPY-06838 PD-L2 Protein, Rhesus, Recombinant (His)

programmed cell death 1 ligand 2

Rhesus HEK293 Cells
PD-L2 Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24 kDa and the accession number is NP_001077068.1.
TMPY-04225 PD-L2 Protein, Rat, Recombinant (His)

programmed cell death 1 ligand 2

Rat HEK293 Cells
PD-L2 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 23.9 kDa and the accession number is D4AAV6.
TMPJ-00137 APRIL/TNFSF13 Protein, Human, Recombinant (Flag & His)

TRDL-1,TNF- and APOL-related leukocyte expressed ligand 2,Tu...

Human HEK293 Cells
APRIL (a proliferation-inducing ligand), also known as TNFSF13, TALL2, TRDL1, and CD256, is a member of the TNF ligand superfamily. It is synthesized as a 32 kDa proprotein which is cleaved by furin in the Golgi to release the active 17 kDa soluble molecule. Secreted human APRIL, which consists almost entirely of a single TNF homology domain, shares 85% amino acid sequence identity with mouse and rat APRIL. Both APRIL and its close relative BAFF bind and signal through the TNF superfamily recept...
TMPY-02027 BID Protein, Human, Recombinant

BH3 interacting domain death agonist,FP497

Human E. coli
BID Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 22 kDa and the accession number is P55957-1.
TMPY-04417 DAPK1 Protein, Human, Recombinant (aa 1-363, His & GST)

DAPK,death-associated protein kinase 1,ROCO3

Human Baculovirus Insect Cells
Death-associated protein kinase 1, also known as DAP kinase 1, DAPK1 and DAPK, is a cytoplasm protein which belongs to theprotein kinase superfamily, CAMK Ser / Thr protein kinase family and DAP kinase subfamily. DAPK1 contains tenANK repeats, onedeath domain and oneprotein kinase domain. DAPK1 is a calcium / calmodulin-dependent serine/threonine kinase which acts as a positive regulator of apoptosis. DAPK1 gene is a candidate tumor suppressor (TSG) and the abnormal methylation of DAPK1 g...
TMPY-04385 ZIP Kinase/DAPK3 Protein, Human, Recombinant (GST)

death-associated protein kinase 3,DLK,ZIP,ZIPK

Human Baculovirus Insect Cells
Death-associated protein kinase 3, also known as DAP kinase 3, ZIP-kinase, DAPK3 and ZIPK, is a nucleus and cytoplasm protein which belongs to theprotein kinase superfamily, CAMK Ser/Thr protein kinase family and DAP kinase subfamily. DAPK3 / ZIPK contains oneprotein kinase domain. It is a serine/threonine kinase which acts as a positive regulator of apoptosis. It phosphorylates histone H3 on 'Thr-11' at centromeres during mitosis. DAPK3 / ZIPK is a homodimer or forms heterodimers with AT...
TMPY-04967 PD-1 Protein, Mouse, Recombinant (His), Biotinylated

PD-1,programmed cell death 1,Ly101,Pdc1

Mouse HEK293 Cells
PD-1 Protein, Mouse, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.6 kDa and the accession number is Q02242.
TMPY-02065 BID Protein, Mouse, Recombinant (His & GST)

AU022477,BH3 interacting domain death agonist,27000...

Mouse E. coli
BID Protein, Mouse, Recombinant (His & GST) is expressed in E. coli expression system with His and GST tag. The predicted molecular weight is 50 kDa and the accession number is EDK99650.1.
TMPJ-00181 PD-1 Protein, Human, Recombinant (His & Avi), Biotinylated

Programmed cell death protein 1,PDCD1,CD279,hPD-1

Human HEK293 Cells
Programmed cell death protein 1(PDCD1) is a single-pass type I membrane protein and contains 1 Ig-like V-type domain. PD-1 is a member of the extended CD28/CTLA-4 family of T cell regulators. PDCD1 inhibits the T-cell proliferation and production of related cytokines including IL-1, IL-4, IL-10 and IFN-γ by suppressing the activation and transduction of PI3K/AKT pathway. In addition, coligation of PDCD1 inhibits BCR-mediating signal by dephosphorylating key signal transducer. PDCD1 has been sugg...
TMPY-03317 DcR2/TRAIL R4 Protein, Rhesus, Recombinant (hFc)

tumor necrosis factor receptor superfamily, member 10d, deco...

Rhesus HEK293 Cells
DcR2/TRAIL R4 Protein, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 42.9 kDa and the accession number is XP_001107922.1.
TMPY-05282 PD-L2 Protein, Mouse, Recombinant (His), Biotinylated

PD-L2,programmed cell death 1 ligand 2,B7-DC,F73001...

Mouse HEK293 Cells
PD-L2 Protein, Mouse, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24 kDa and the accession number is Q9WUL5.
TMPJ-00183 PD-L1 Protein, Human, Recombinant (Flag)

B7-H1,Programmed Cell Death 1 Ligand 1,PD-L1,PDCD1L...

Human HEK293 Cells
PD-L1 Protein, Human, Recombinant (Flag) is expressed in HEK293 mammalian cells with C-Flag tag. The predicted molecular weight is 35-40 KDa and the accession number is Q9NZQ7.
TMPJ-00182 PD-L1 Protein, Human, Recombinant (hFc & Avi), Biotinylated

B7-H1,PDCD1LG1,PD-L1,PDCD1L1,B7 homolog 1,Programmed dea...

Human HEK293 Cells
PD-L1 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-Fc-Avi tag. The predicted molecular weight is 70-95 KDa and the accession number is Q9NZQ7.
TMPY-03318 DcR2/TRAIL R4 Protein, Rhesus, Recombinant (His)

tumor necrosis factor receptor superfamily, member 10d, deco...

Rhesus HEK293 Cells
DcR2/TRAIL R4 Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.3 kDa and the accession number is XP_001107922.1.
TMPH-02948 TRIB3 Protein, Mouse, Recombinant (His & Myc)

Tribbles homolog 3,Trib3,Neuronal cell death-induci...

Mouse E. coli
TRIB3 Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 46.5 kDa and the accession number is Q8K4K2.
TMPY-02436 PD-L2 Protein, Mouse, Recombinant (hFc)

F730015O22Rik,Btdc,PD-L2,programmed cell death 1 li...

Mouse HEK293 Cells
PD-L2 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.5 kDa and the accession number is Q9WUL5.
TMPY-02352 PD-L2 Protein, Mouse, Recombinant (His)

programmed cell death 1 ligand 2,Btdc,F730015O22Rik...

Mouse HEK293 Cells
PD-L2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24 kDa and the accession number is Q9WUL5.
TMPY-02213 RAIDD Protein, Human, Recombinant (His)

RAIDD,MRT34,CASP2 and RIPK1 domain containing adaptor with <...

Human E. coli
Death domain-containing protein CRADD, also known as Caspase and RIP adapter with death domain, RIP-associated protein with a death domain, CRADD and RAIDD, is a protein which is constitutively expressed in most tissues, with particularly high expression in adult heart, testis, liver, skeletal muscle, fetal liver and kidney. CRADD / RAIDD contains oneCARD domain and onedeath domain. CRADD / RAIDD contains a death domain involved in the binding of RIP protein. The CARD domain mediates the ...
TMPY-05619 PD-1 Protein, Human, Recombinant (His), Biotinylated

hPD-l,PD-1,SLEB2,PD1,hPD-1,programmed cell death 1,...

Human HEK293 Cells
PD-1 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.4 kDa and the accession number is A0A0M3M0G7.
TMPY-06682 PD-1 Protein, Human, Recombinant (Asp26-Pro39 deletion, His)

hPD-1,hSLE1,hPD-l,CD279,PD1,PD-1,programmed cell death

Human HEK293 Cells
PD-1 Protein, Human, Recombinant (Asp26-Pro39 deletion, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 18.65 kDa and the accession number is NP_005009.2.
TMPJ-00246 TRAIL R2/DR5/TNFRSF10B Protein, Mouse, Recombinant (hFc)

MK,CD262,Tnfrsf10b,Dr5,Tumor necrosis factor receptor superf...

Mouse HEK293 Cells
TRAIL R2/DR5/TNFRSF10B Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 50-75 KDa and the accession number is Q9QZM4.
TMPJ-00718 AIF Protein, Human, Recombinant (His)

AIF,Apoptosis-Inducing Factor 1 Mitochondrial,PDCD8,Programm...

Human E. coli
Apoptosis-Inducing Factor 1, Mitochondrial (AIFM1) is a flavoprotein essential for nuclear disassembly in apoptotic cells that is found in the mitochondrial intermembrane space in healthy cells. During apoptosis, it is translocated from the mitochondria to the nucleus to function as a proapoptotic factor in a caspase-independent pathway, while in normal mitochondria, it functions as an antiapoptotic factor via its oxidoreductase activity. The soluble form (AIFsol) found in the nucleus induces pa...
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重组蛋白

PD-1 Protein, Canine, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-05815
Species: Canine
Expression System: HEK293 Cells
PD-1 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPY-05260
Species: Cynomolgus
Expression System: HEK293 Cells
PD-1 Protein, Canine, Recombinant (His)
Cat.No: TMPY-04342
Species: Canine
Expression System: HEK293 Cells
PD-1 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-05395
Species: Mouse
Expression System: HEK293 Cells
PD-1 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-00996
Species: Mouse
Expression System: HEK293 Cells
PD-1 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-04898
Species: Human
Expression System: HEK293 Cells
PD-1 Protein, Human, Recombinant (His)
Cat.No: TMPY-00897
Species: Human
Expression System: HEK293 Cells
PD-1 Protein, Human, Recombinant (mFc)
Cat.No: TMPY-05079
Species: Human
Expression System: HEK293 Cells
PD-L2 Protein, Human, Recombinant (mFc)
Cat.No: TMPY-05827
Species: Human
Expression System: HEK293 Cells
PD-L2 Protein, Human, Recombinant (His), Biotinylated
Cat.No: TMPY-04957
Species: Human
Expression System: HEK293 Cells
PD-L2 Protein, Human, Recombinant (His)
Cat.No: TMPY-04346
Species: Human
Expression System: HEK293 Cells
PD-1 Protein, Cynomolgus, Recombinant (hFc)
Cat.No: TMPY-00253
Species: Cynomolgus
Expression System: HEK293 Cells
PD-1 Protein, Rat, Recombinant (hFc)
Cat.No: TMPY-03717
Species: Rat
Expression System: HEK293 Cells
PD-1 Protein, Rhesus, Recombinant (His)
Cat.No: TMPY-00250
Species: Rhesus
Expression System: HEK293 Cells
PD-1 Protein, Rhesus, Recombinant (hFc)
Cat.No: TMPY-00633
Species: Rhesus
Expression System: HEK293 Cells
CRADD Protein, Human, Recombinant
Cat.No: TMPJ-01059
Species: Human
Expression System: E. coli
Dengue virus DENV-2 (Strain New Guinea C) Capsid protein/DENV-C Protein (His)
Cat.No: TMPY-00047
Species: DENV
Expression System: E. coli
PD-1 Protein, Rat, Recombinant (His)
Cat.No: TMPY-04341
Species: Rat
Expression System: HEK293 Cells
PD-1 Protein, Canine, Recombinant (hFc)
Cat.No: TMPY-00233
Species: Canine
Expression System: HEK293 Cells
PD-1 Protein, Cynomolgus, Recombinant (hFc & Avi), Biotinylated
Cat.No: TMPY-05295
Species: Cynomolgus
Expression System: HEK293 Cells
Fas/CD95 Protein, Cynomolgus, Recombinant (hFc)
Cat.No: TMPY-03834
Species: Cynomolgus
Expression System: HEK293 Cells
Fas/CD95 Protein, Rat, Recombinant (hFc)
Cat.No: TMPY-04282
Species: Rat
Expression System: HEK293 Cells
PD-L2 Protein, Rat, Recombinant (hFc)
Cat.No: TMPY-04223
Species: Rat
Expression System: HEK293 Cells
PD-L2 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPY-03738
Species: Cynomolgus
Expression System: HEK293 Cells
Fas/CD95 Protein, Rat, Recombinant (His)
Cat.No: TMPY-02057
Species: Rat
Expression System: HEK293 Cells
Fas/CD95 Protein, Cynomolgus, Recombinant
Cat.No: TMPY-00632
Species: Cynomolgus
Expression System: HEK293 Cells
PD-L2 Protein, Rhesus, Recombinant (hFc)
Cat.No: TMPY-06819
Species: Rhesus
Expression System: HEK293 Cells
PD-L2 Protein, Cynomolgus, Recombinant (hFc)
Cat.No: TMPY-03404
Species: Cynomolgus
Expression System: HEK293 Cells
PD-L2 Protein, Rhesus, Recombinant (His)
Cat.No: TMPY-06838
Species: Rhesus
Expression System: HEK293 Cells
PD-L2 Protein, Rat, Recombinant (His)
Cat.No: TMPY-04225
Species: Rat
Expression System: HEK293 Cells
APRIL/TNFSF13 Protein, Human, Recombinant (Flag & His)
Cat.No: TMPJ-00137
Species: Human
Expression System: HEK293 Cells
BID Protein, Human, Recombinant
Cat.No: TMPY-02027
Species: Human
Expression System: E. coli
DAPK1 Protein, Human, Recombinant (aa 1-363, His & GST)
Cat.No: TMPY-04417
Species: Human
Expression System: Baculovirus Insect Cells
ZIP Kinase/DAPK3 Protein, Human, Recombinant (GST)
Cat.No: TMPY-04385
Species: Human
Expression System: Baculovirus Insect Cells
PD-1 Protein, Mouse, Recombinant (His), Biotinylated
Cat.No: TMPY-04967
Species: Mouse
Expression System: HEK293 Cells
BID Protein, Mouse, Recombinant (His & GST)
Cat.No: TMPY-02065
Species: Mouse
Expression System: E. coli
PD-1 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPJ-00181
Species: Human
Expression System: HEK293 Cells
DcR2/TRAIL R4 Protein, Rhesus, Recombinant (hFc)
Cat.No: TMPY-03317
Species: Rhesus
Expression System: HEK293 Cells
PD-L2 Protein, Mouse, Recombinant (His), Biotinylated
Cat.No: TMPY-05282
Species: Mouse
Expression System: HEK293 Cells
PD-L1 Protein, Human, Recombinant (Flag)
Cat.No: TMPJ-00183
Species: Human
Expression System: HEK293 Cells
PD-L1 Protein, Human, Recombinant (hFc & Avi), Biotinylated
Cat.No: TMPJ-00182
Species: Human
Expression System: HEK293 Cells
DcR2/TRAIL R4 Protein, Rhesus, Recombinant (His)
Cat.No: TMPY-03318
Species: Rhesus
Expression System: HEK293 Cells
TRIB3 Protein, Mouse, Recombinant (His & Myc)
Cat.No: TMPH-02948
Species: Mouse
Expression System: E. coli
PD-L2 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-02436
Species: Mouse
Expression System: HEK293 Cells
PD-L2 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-02352
Species: Mouse
Expression System: HEK293 Cells
RAIDD Protein, Human, Recombinant (His)
Cat.No: TMPY-02213
Species: Human
Expression System: E. coli
PD-1 Protein, Human, Recombinant (His), Biotinylated
Cat.No: TMPY-05619
Species: Human
Expression System: HEK293 Cells
PD-1 Protein, Human, Recombinant (Asp26-Pro39 deletion, His)
Cat.No: TMPY-06682
Species: Human
Expression System: HEK293 Cells
TRAIL R2/DR5/TNFRSF10B Protein, Mouse, Recombinant (hFc)
Cat.No: TMPJ-00246
Species: Mouse
Expression System: HEK293 Cells
AIF Protein, Human, Recombinant (His)
Cat.No: TMPJ-00718
Species: Human
Expression System: E. coli
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Cat. No. Product Name Target Signaling Pathways
TMID-0018 Paclitaxel-d5

ADC Cytotoxin Antibody-drug Conjugate/ADC Related
Paclitaxel-d5 是 Paclitaxel 的氘代化合物。Paclitaxel 的 CAS 号为 33069-62-4。Paclitaxel 是一种从太平洋紫杉树皮中分离出来的环癸烷。 它以聚合形式稳定微管,导致细胞死亡。
TMID-0194 Ofloxacin-d8

Ofloxacin-d8 是 Ofloxacin 的氘代化合物。Ofloxacin 的 CAS 号为 82419-36-1。Ofloxacin是可抑制细菌DNA旋转酶的一种氟喹诺酮类抗生素。
TMIJ-0274 Sulindac-d3

Sulindac-d3 是 Sulindac 的氘代化合物。Sulindac 的 CAS 号为 38194-50-2。Sulindac 是一种非甾体类抗炎剂,可抑制COX-2的活性,也可抑制 COX-2 的过表达。它是一种亚磺酰基茚衍生物前药,具有潜在的抗肿瘤活性。
TMID-0078 Irinotecan-d10 Hydrochloride

Irinotecan-d10 Hydrochloride 是 Irinotecan Hydrochloride 的氘代化合物。Irinotecan Hydrochloride 的 CAS 号为 100286-90-6。Irinotecan Hydrochloride 是喜树碱半合成衍生物的盐酸盐,是一种拓扑异构酶 I 抑制剂,可研究结肠癌和直肠癌。
T69995 Chlorhexidine-d8 HCl

Chlorhexidine-d8 is intended for use as an internal standard for the quantification of chlorhexidine by GC- or LC-MS. Chlorhexidine is a bis(biguanide) antimicrobial disinfectant and antiseptic agent. It inhibits growth of clinical methicillin-resistant S. aureus (MRSA) isolates (MIC90 = 4 μg/ml). It is also active against canine isolates of MRSA, methicillin-susceptible S. aureus (MSSA), methicillin-resistant S. pseudintermedius (MRSP), and methicillin-susceptible S. pseudintermedius (MSSP; MIC...
T71142 Tebuconazole-d9

Tebuconazole-d9 is intended for use as an internal standard for the quantification of tebuconazole by GC- or LC-MS. Tebuconazole is a triazole fungicide that is active against both seed and foliar fungi. It inhibits 14α-demethylase isolated from U. maydis and S. bicolor with IC50 values of 0.05 and 0.16 nM, respectively. It inhibits the androgenic effect of the androgen receptor agonist DHT (IC20 = 2.89 µM) and is cytotoxic (EC20 = 38.9 µM) in an MDA-kb2 assay. Tebuconazole (50 and 100 mg/kg per...

同位素标记化合物

Paclitaxel-d5
Cat.No: TMID-0018
Synonym:
Target: ADC Cytotoxin
Ofloxacin-d8
Cat.No: TMID-0194
Synonym:
Target:
Sulindac-d3
Cat.No: TMIJ-0274
Synonym:
Target:
Irinotecan-d10 Hydrochloride
Cat.No: TMID-0078
Synonym:
Target:
Chlorhexidine-d8 HCl
Cat.No: T69995
Synonym:
Target:
Tebuconazole-d9
Cat.No: T71142
Synonym:
Target:
TargetMol Loading
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