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RIP3 activator 1 (compound C8) 作为一种高效的RIP3激活剂,能够抑制细胞生长,并通过RIP3/p62/Keap1信号通路促进坏死性凋亡 (necroptosis) 和自噬 (autophagy)。此外,该化合物还能增加p-MLKL、LC3-II及p62蛋白的表达水平。
RIP3 activator 1 (compound C8) 作为一种高效的RIP3激活剂,能够抑制细胞生长,并通过RIP3/p62/Keap1信号通路促进坏死性凋亡 (necroptosis) 和自噬 (autophagy)。此外,该化合物还能增加p-MLKL、LC3-II及p62蛋白的表达水平。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
10 mg | 询价 | 10-14周 | |
50 mg | 询价 | 10-14周 |
产品描述 | RIP3 Activator 1 (compound C8) is an effective RIP3 activator that inhibits cell growth and induces necroptotic cell death (necroptosis) and autophagy through the RIP3/p62/Keap1 signaling pathway. Additionally, this compound enhances the expression of p-MLKL and promotes the accumulation of LC3-II and p62 proteins. |
分子量 | 466.7 |
分子式 | C26H50N4O3 |
CAS No. | 1456899-52-7 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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