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DMBA (7,12-Dimethylbenz[a]anthracene) 可诱导大鼠白血病、肝癌和乳腺癌,诱导 A20.1 小鼠 B 细胞淋巴瘤中的程序性细胞死亡(细胞凋亡)。
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DMBA (7,12-Dimethylbenz[a]anthracene) 可诱导大鼠白血病、肝癌和乳腺癌,诱导 A20.1 小鼠 B 细胞淋巴瘤中的程序性细胞死亡(细胞凋亡)。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
5 mg | ¥ 137 | 现货 | |
10 mg | ¥ 186 | 现货 | |
25 mg | ¥ 289 | 现货 | |
50 mg | ¥ 413 | 现货 | |
100 mg | ¥ 662 | 现货 | |
1 mL x 10 mM (in DMSO) | ¥ 198 | 现货 |
产品描述 | DMBA (7,12-Dimethylbenz[a]anthracene) induces leukemia, hepatocellular carcinoma, and mammary carcinoma in rats, and programmed cell death (apoptosis) in B-cell lymphomas in A20.1 mice. |
体内活性 | DMBA (0-150 mg/kg,口服) 导致 C57BL/6 小鼠的脾脏重量减少,从脾脏中回收的淋巴细胞总数减少, 可用于构建诱导皮肤致癌、乳腺癌以及肺癌等癌症模型[5]。 |
别名 | 7,12-DMBA, 7,12-Dimethylbenzanthracene, 7,12-Dimethylbenz[a]anthracene |
分子量 | 256.34 |
分子式 | C20H16 |
CAS No. | 57-97-6 |
Smiles | Cc1c2ccccc2c(C)c2c1ccc1ccccc21 |
存储 | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
溶解度信息 | Ethanol: 2 mg/mL (7.80 mM), Sonication and heating are recommended. DMSO: 15 mg/mL (58.5 mM), Sonification is recommended. Acetone: 15 mg/mL (58.5 mM), Sonification is recommended. DMF: 20 mg/mL | |||||||||||||||||||||||||||||||||||
溶液配制表 | ||||||||||||||||||||||||||||||||||||
Ethanol/DMSO/Acetone
DMSO/Acetone
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