3 hydroxy midostaurin d5

3-Hydroxy Midostaurin-D5 (CGP52421-D5) is a deuterium-labeled 3-Hydroxy Midostaurin which is a metabolite of PKC412. PKC412 effectively inhibits FMS-like tyrosine kinase-3 (FLT3) autophosphorylation (IC50s: 132 nM and 9.8 μM in culture medium and plasma).

3 Hydroxy Midostaurin Epimer 2-d5 是 3 Hydroxy Midostaurin Epimer 2 的氘代化合物。3 Hydroxy Midostaurin Epimer 2 的 CAS 号为 155848-20-7。

3 Hydroxy Midostaurin Epimer 1-d5 是 3 Hydroxy Midostaurin Epimer 1 的氘代化合物。3 Hydroxy Midostaurin Epimer 1 的 CAS 号为 945260-14-0。

3-phenylpropionic acid-d5 是 3-phenylpropionic acid 的氘代化合物。

Indole-2,4,5,6,7-d5-3-acetic-2,2-d2 Acid 是 Indole-3-acetic Acid 的氘代化合物。Indole-3-acetic Acid 的 CAS 号为 87-51-4。3-Indoleacetic acid 是常见的天然植物生长激素。它可以诱导植物细胞的伸长和分裂。

ortho-Hydroxy Atorvastatin-d5 Calcium Salt 是 ortho-Hydroxy Atorvastatin Calcium Salt 的氘代化合物。ortho-Hydroxy Atorvastatin Calcium Salt 的 CAS 号为 265989-47-7。

5-Hydroxy Saxagliptin-13C-d2 HCl 是 5-Hydroxy Saxagliptin HCl 的 13C 和氘代化合物。5-Hydroxy Saxagliptin HCl 的 CAS 号为 841302-24-7。

Midostaurin-D5 is a deuterium labeled Midostaurin.

1-Palmitoyl-d9-2-hydroxy-sn-glycero-3-PE serves as an internal standard for quantifying 1-palmitoyl-2-hydroxy-sn-glycero-3-PE, a lysophospholipid naturally found to inhibit L. donovani promastigotes growth (GI50= 8 µM). Its levels are reduced in mice after alcohol-induced liver damage, in hepatocellular carcinoma mouse xenografts, and in humans following a rigorous three-day exercise regimen of 2.5 hours running daily and 14 hours post-regimen. This compound is also applied in measuring saturated lysophosphoethanolamines, highlighting its broad utility in biochemical research and disease model studies.

rac 1,2-Bis-palmitoyl-3-chloropropanediol-d5 是 rac 1,2-Bis-palmitoyl-3-chloropropanediol 的氘代化合物。rac 1,2-Bis-palmitoyl-3-chloropropanediol 的 CAS 号为 51930-97-3。

Remdesivir Impurity 5-d5 是 Remdesivir Impurity 5 的氘代化合物。

1-Palmitoyl-d9-2-hydroxy-sn-glycero-3-PA (1-palmitoyl-d9LPA) serves as an internal standard for the quantification of 1-palmitoyl LPA using GC- or LC-MS. This compound, an analog of LPA with palmitic acid at the sn-1 position, activates reporter gene expression in PC12 cells fitted with human lysophosphatidic acid receptor 4 (LPA4) at 0.01 to 10 µM concentrations. Additionally, 1-palmitoyl LPA prompts aggregation in isolated human platelets within the 12-300 µM range, a process reversible by prostaglandin E1 (PGE1), theophylline, or EDTA. It also interacts with calcium and magnesium to boost the efficacy of ampicillin, piperacillin, and ceftazidime against P. aeruginosa strains from cystic fibrosis patients.

3-Hydroxy Desloratadine-d4 是 3-Hydroxy Desloratadine 的氘代化合物。

7-Hydroxy Warfarin-d5 是 7-Hydroxy Warfarin 的氘代化合物。7-Hydroxy Warfarin 的 CAS 号为 17834-03-6。

ortho-Hydroxy Atorvastatin-d5 Lactone 是 ortho-Hydroxy Atorvastatin Lactone 的氘代化合物。

(4-Hydroxy-3-methoxyphenyl)acetic-2,2-d2 Acid 是 (4-Hydroxy-3-methoxyphenyl)acetic Acid 的氘代化合物。(4-Hydroxy-3-methoxyphenyl)acetic Acid 的 CAS 号为 306-08-1。Homovanillic acid 是一种多巴胺代谢物，它与乳糜泻、生长激素缺乏、芳香族氨基酸脱羧酶缺乏症以及脂联素还原酶缺乏症相关。

rac 1-Palmitoyl-3-Chloropropanediol-d5 是 rac 1-Palmitoyl-3-Chloropropanediol 的氘代化合物。rac 1-Palmitoyl-3-Chloropropanediol 的 CAS 号为 30557-04-1。

DL-4-Hydroxy-3-methoxymandelic-d3 acid 是 DL-4-Hydroxy-3-methoxymandelic acid 的氘代化合物。

3-Hydroxy Repaglinide-d5 是 3-Hydroxy Repaglinide 的氘代化合物。

3-Chloro-1,2-Propanediol-d5 是 3-Chloro-1,2-Propanediol 的氘代化合物。3-Chloro-1,2-Propanediol 的 CAS 号为 96-24-2。

Ethyl-β-D-glucuronide-d5 是 Ethyl-β-D-glucuronide 的氘代化合物。Ethyl-β-D-glucuronide 的 CAS 号为 17685-04-0。

2-hydroxy-4-methoxybenzophenone-d5 是 2-hydroxy-4-methoxybenzophenone 的氘代化合物。2-hydroxy-4-methoxybenzophenone 的 CAS 号为 131-57-7。Oxybenzone 是晒黑和皮肤保护剂中常用的紫外线过滤剂。它是二苯甲酮的衍生物，用作破坏内分泌的化学物质，可穿透胎盘和血脑屏障。它损害自噬，改变表观遗传状态并破坏凋亡神经元细胞中的类维生素 X 受体信号传导。

O-Desmethyl Midostaurin-d5 是 O-Desmethyl Midostaurin 的氘代化合物。

5-Hydroxy tryptophol β-D glucuronide-d4 是 5-Hydroxy tryptophol β-D glucuronide 的氘代化合物。

5-Hydroxy Propafenone D5 HCl is the deuterium labeled 5-Hydroxy Propafenone.

3-Hydroxy agomelatine D3 is a deuterium labeled 3-Hydroxy agomelatine. 3-Hydroxy agomelatine is an Agomelatine metabolite and a 5-HT2C receptor antagonist (IC50: 3.2 μM; Ki: 1.8 μM).

para-Hydroxy Atorvastatin-d5 Calcium Salt 是 para-Hydroxy Atorvastatin Calcium Salt 的氘代化合物。para-Hydroxy Atorvastatin Calcium Salt 的 CAS 号为 214217-88-6。

5-Hydroxy Propafenone-d5 HCl 是 5-Hydroxy Propafenone HCl 的氘代化合物。

5-Hydroxyindole-3-acetic Acid-d6 是 5-Hydroxyindole-3-acetic Acid 的氘代化合物。5-Hydroxyindole-3-acetic Acid 的 CAS 号为 54-16-0。5-Hydroxyindole-3-acetic acid 是 甲氧基肾上腺素或5-羟色胺的主要代谢产物，被用作神经内分泌肿瘤的生物标志物。它是血清素的分解产物，能够从尿液中排出。

Indole-2,4,5,6,7-d5-3-acetic Acid 是 Indole-3-acetic Acid 的氘代化合物。Indole-3-acetic Acid 的 CAS 号为 87-51-4。3-Indoleacetic acid 是常见的天然植物生长激素。它可以诱导植物细胞的伸长和分裂。

Methyl Indole-2,4,5,6,7-d5-3-acetate 是 Methyl Indole-2,4,5,6,7-3-acetate 的氘代化合物。

5-Hydroxy-L-tryptophan-4,6,7-d3 是 5-Hydroxy-L-tryptophan 的氘代化合物。5-Hydroxy-L-tryptophan 的 CAS 号为 314062-44-7。