|
TMPH-00758
|
EspK Protein, Mycobacterium tuberculosis, Recombinant (His & Myc)
espK,ESX-1 secretion-associated protein EspK
|
Mycobacterium tuberculosis
|
E. coli
|
|
May act as a chaperone that facilitates EspB secretion through an interaction with EccCb1. |
|
TMPH-03550
|
EsxA Protein, S. aureus, Recombinant (His & SUMO)
esxA,Type VII secretion system extracellular protei...
|
Staphylococcus aureus
|
E. coli
|
|
Virulence factor that is important for the establishment of infection in the host. EsxA is required for EsxB synthesis as well as secretion. Modulates host cell apoptotic pathways and mediates together with EsxB the release of S.aureus from the host cell. By acting on apoptosis, plays a role in the modulation of dendritic cell-mediated immunity. EsxA Protein, S. aureus, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 27.... |
|
TMPH-03478
|
PrgI Protein, Salmonella typhimurium, Recombinant (His & SUMO)
SPI-1 type 3 secretion system needle filament prote...
|
Salmonella typhimurium
|
E. coli
|
|
Required for invasion of epithelial cells. |
|
TMPH-03506
|
IpaB Protein, Shigella flexneri, Recombinant (His)
62 kDa antigen,sctE,Type 3 secretion system translo...
|
Shigella flexneri
|
E. coli
|
|
IpaB Protein, Shigella flexneri, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 40.6?kDa and the accession number is P18011. |
|
TMPH-00319
|
Type III secretion system needle Protein, Burkholderia thailandensis, Recombinant (His)
yscF
|
Burkholderia thailandensis
|
P. pastoris (Yeast)
|
|
Type III secretion system needle Protein, Burkholderia thailandensis, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 11.9 kDa and the accession number is Q2T727. |
|
TMPH-03718
|
YopB Protein, Yersinia enterocolitica, Recombinant (His)
Type 3 secretion system translocon protein SctE,sct...
|
Yersinia enterocolitica
|
E. coli
|
|
Plays a role in virulence. |
|
TMPH-01850
|
PNPLA2 Protein, Human, Recombinant (His & SUMO)
Transport-secretion protein 2,Patatin-like phosphol...
|
Human
|
E. coli
|
|
PNPLA2 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 71.3 kDa and the accession number is Q96AD5. |
|
TMPJ-01471
|
Activin A Protein, Human, Mouse, Rat, Cynomolgus, Rhesus, Recombinant
Activin A,INHBA,Inhibin beta A chain,Inhibin β A chain
|
Human/Mouse/Rat
|
HEK293 Cells
|
|
Activin and inhibin are two closely related protein complexes that have almost directly opposite biological effects. Activins, members of the TGF-beta superfamily, are disulfide-linked dimeric proteins originally purified from gonadal fluids as proteins that stimulated pituitary follicle stimulating hormone (FSH) release. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell developm... |
|
TMPY-00545
|
Dermcidin Protein, Human, Recombinant (hFc)
AIDD,PIF,HCAP,dermcidin,DCD-1,DSEP
|
Human
|
HEK293 Cells
|
|
Hepatocellular carcinoma (HCC) is a major contributor to cancer-related deaths due to its often late stage diagnosis, and dermcidin (DCD) may have the potential to be used as a serum biomarker for HCC for more timely diagnoses. Human dermcidin (DCD) is an antimicrobial peptide secreted constitutively by sweat glands. And the role of DCD in ischemic heart disease has drawn increasing attention in particular its relationship with insulin secretion and glycemic control, nitric oxide (NO) synthesis ... |
|
TMPY-02904
|
TLR4 Protein, Human, Recombinant (His)
TLR-4,TOLL,toll-like receptor 4,ARMD10,TLR4,CD284
|
Human
|
Baculovirus Insect Cells
|
|
TLR4, also known as TLR-4, is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. TLR4 is most abundantly expressed... |
|
TMPH-03507
|
IpaD Protein, Shigella flexneri, Recombinant (His & Myc & SUMO)
ipaD,36 kDa membrane antigen,Invasin IpaD
|
Shigella flexneri
|
E. coli
|
|
Required for bacterial invasion of host cells. Controls IpaB and IpaC secretion, and the efficiency with which they are physically inserted into target cell membranes. These proteins are exported via TTSS to form a pore in the host membrane that allows the translocation of the other effectors into the host cytoplasm. Along with IpaB, is essential for both blocking secretion through the Mxi/Spa translocon in the absence of a secretion-inducing signal, and for controlling the level of secretion in... |
|
TMPJ-01016
|
INHBC Protein, Human, Recombinant (N-His)
Activin Beta-C Chain,INHBC,Inhibin β C Chain,Activin β-C Cha...
|
Human
|
E. coli
|
|
Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins,Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary... |
|
TMPH-01564
|
ICA1 Protein, Human, Recombinant (His)
Islet cell autoantigen p69,ICA1,69 kDa islet cell autoantige...
|
Human
|
P. pastoris (Yeast)
|
|
May play a role in neurotransmitter secretion. |
|
TMPH-01530
|
INHBA Protein, Human, Recombinant (His & SUMO)
Activin beta-A chain,INHBA,Inhibin beta A chain,Erythroid di...
|
Human
|
E. coli
|
|
Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of a... |
|
TMPH-01514
|
IGIP Protein, Human, Recombinant (His & TF)
IgA-inducing protein homolog,IGIP
|
Human
|
Baculovirus Insect Cells
|
|
Enhances IgA secretion from B-cells stimulated via CD40. |
|
TMPH-03354
|
Progonadoliberin-1/GNRH1 Protein, Rat, Recombinant (His)
Progonadoliberin-1,Gnrh1,Progonadoliberin I
|
Rat
|
E. coli
|
|
Stimulates the secretion of gonadotropins; it stimulates the secretion of both luteinizing and follicle-stimulating hormones. Progonadoliberin-1/GNRH1 Protein, Rat, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 12.2 kDa and the accession number is P07490. |
|
TMPH-01513
|
IGIP Protein, Human, Recombinant (His & KSI)
IgA-inducing protein homolog,IGIP
|
Human
|
E. coli
|
|
Enhances IgA secretion from B-cells stimulated via CD40. |
|
TMPH-02843
|
NPY Protein, Mouse, Recombinant (hFc)
Pro-neuropeptide Y,Npy
|
Mouse
|
P. pastoris (Yeast)
|
|
NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone. |
|
TMPH-02823
|
Peptide YY/PYY Protein, Mouse, Recombinant (GST)
Peptide tyrosine tyrosine,Pyy,Peptide YY
|
Mouse
|
E. coli
|
|
This gut peptide inhibits exocrine pancreatic secretion, has a vasoconstrictory action and inhibitis jejunal and colonic mobility. |
|
TMPJ-01015
|
INHBC Protein, Human, Recombinant (C-His)
Activin β-C Chain,Activin Beta-C Chain,Inhibin β C Chain,INH...
|
Human
|
HEK293 Cells
|
|
Inhibin beta C chain, also known as activin beta-C chain and INHBC, belongs to the TGF-beta family. INHBC forms a homodimeric or heterodimeric through association with alpha and beta subunits, linked by one or more disulfide bonds. Inhibins are heterodimers of one alpha and one beta subunit. Activins are homo- or heterodimers of beta subunits only. Inhibins/activins regulates many physiological processes, such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell ... |
|
TMPH-00546
|
Epstein-Barr virus (strain GD1) BARF1 Protein (His)
33 kDa early protein,BARF1,p33,Secreted protein BARF1
|
EBV
|
E. coli
|
|
Plays diverse functions in immunomodulation and oncogenicity, maybe by acting as a functional receptor for human CSF1. May inhibit interferon secretion from mononuclear cells. Exhibits oncogenic activity in vitro. |
|
TMPH-02716
|
HADH Protein, Mouse, Recombinant (His & SUMO)
Short-chain 3-hydroxyacyl-CoA dehydrogenase,Hydroxyacyl-coen...
|
Mouse
|
E. coli
|
|
Mitochondrial fatty acid beta-oxidation enzyme that catalyzes the third step of the beta-oxidation cycle for medium and short-chain 3-hydroxy fatty acyl-CoAs (C4 to C10). Plays a role in the control of insulin secretion by inhibiting the activation of glutamate dehydrogenase 1 (GLUD1), an enzyme that has an important role in regulating amino acid-induced insulin secretion. HADH Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted... |
|
TMPH-00547
|
Epstein-Barr virus (strain B95-8) BARF1 Protein (His & Myc)
33 kDa early protein,p33,Secreted protein BARF1
|
EBV
|
E. coli
|
|
Plays diverse functions in immunomodulation and oncogenicity, maybe by acting as a functional receptor for human CSF1. May inhibit interferon secretion from mononuclear cells. Exhibits oncogenic activity in vitro. |
|
TMPH-02130
|
SPTAN1 Protein, Human, Recombinant (His & SUMO)
Fodrin alpha chain,Spectrin alpha chain, non-erythrocytic 1,...
|
Human
|
E. coli
|
|
Fodrin, which seems to be involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus candidate for the calcium-dependent movement of the cytoskeleton at the membrane. |
|
TMPH-02514
|
APOA4 Protein, Mouse, Recombinant (His)
Apolipoprotein A4,Apolipoprotein A-IV,ApoA-IV,Apo-AIV,Apoa4
|
Mouse
|
P. pastoris (Yeast)
|
|
May have a role in chylomicrons and VLDL secretion and catabolism. Required for efficient activation of lipoprotein lipase by ApoC-II; potent activator of LCAT. Apoa-IV is a major component of HDL and chylomicrons. |
|
TMPH-02581
|
Chymase 1 Protein, Mouse, Recombinant (His)
Mast cell protease 5,Mast cell protease I,Alpha-chymase,Chym...
|
Mouse
|
E. coli
|
|
Major secreted protease of mast cells with suspected roles in vasoactive peptide generation, extracellular matrix degradation, and regulation of gland secretion. Chymase 1 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 29.2 kDa and the accession number is P21844. |
|
TMPH-01852
|
Peptide YY/PYY Protein, Human, Recombinant (GST)
Peptide tyrosine tyrosine,PYY-I,PYY,Peptide YY
|
Human
|
E. coli
|
|
This gut peptide inhibits exocrine pancreatic secretion, has a vasoconstrictory action and inhibitis jejunal and colonic mobility. Peptide YY/PYY Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 31.1 kDa and the accession number is P10082. |
|
TMPH-03293
|
FGF-23 Protein, Rat, Recombinant (E. coli, His)
Fgf23,Fibroblast growth factor 23
|
Rat
|
E. coli
|
|
Regulator of phosphate homeostasis. Inhibits renal tubular phosphate transport by reducing SLC34A1 levels. Regulator of vitamin-D metabolism. Negatively regulates osteoblasts differentiation and matrix mineralization. Acts directly on the parathyroid to decrease PTH secretion. Upregulates EGR1 expression in the presence of KL. |
|
TMPJ-01079
|
TFF2 Protein, Mouse, Recombinant (His)
SP,Trefoil Factor 2,Spasmolytic polypeptide,Tff2,Sml1
|
Mouse
|
HEK293 Cells
|
|
Recombinant Murine TFF-2 is an 11.9 kDa polypeptide of 106 amino acid residues, which includes a 40-amino acid trefoil motif containing three conserved intramolecular disulfide bonds. The Trefoil Factor peptides (TFF1, TFF2 and TFF3) are expressed in the gastrointestinal tract, and appear to play an important role in intestinal mucosal defense and repair. TFF2 has been shown to inhibit gastrointestinal motility and gastric acid secretion. Recent data suggests a potential role for TFF2 in acute a... |
|
TMPJ-00081
|
CNTF Protein, Human, Recombinant
CNTF,Ciliary Neurotrophic Factor
|
Human
|
E. coli
|
|
Ciliary Neurotrophic Factor (CNTF) is a potent survival factor for neurons and oligodendrocytes. CNTF has also been shown to prevent the degeneration of motor axons after axotomy. CNTF is highly conserved across species and exhibits cross-species activities. Human and rat CNTF share approximately 83% homology in their protein sequence. CNTF is structurally related to IL6, IL11, LIF and OSM. All of these four helix bundle cytokines share gp130 as a signal transducing subunit in their receptor com... |
|
TMPH-02937
|
TLR11 Protein, Mouse, Recombinant (His & Myc)
Toll-like receptor 11,Toll-like receptor 12,Tlr11
|
Mouse
|
E. coli
|
|
Participates in the innate immune response to microbial agents. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. TLR11 Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 25.7 kDa and the accession number is Q6R5P0. |
|
TMPY-02640
|
FAM3B Protein, Human, Recombinant (hFc)
PANDER,ORF9,PRED44,C21orf11,C21orf76,42056,family with seque...
|
Human
|
HEK293 Cells
|
|
Pancreatic derived factor, also known as FAM3B, is an islet-specific secreted cytokine specifically expressed at high levels in the islets of Langerhans of the endocrine pancreas. FAM3B protein is present in alpha- and beta- cells of pancreatic islets, insulin-secreting beta-TC3 cells, and glucagon-secreting alpha-TC cells. FAM3B causes apoptosis of beta-cells as assessed by electron microscopy, annexin Ⅴ fluorescent staining, and flow-cytometric terminal deoxynucleotidyl transferase-mediated dU... |
|
TMPH-01094
|
CELA2A Protein, Human, Recombinant (His)
Chymotrypsin-like elastase family member 2A,CELA2A,ELA2A,Ela...
|
Human
|
P. pastoris (Yeast)
|
|
Elastase that enhances insulin signaling and might have a physiologic role in cellular glucose metabolism. Circulates in plasma and reduces platelet hyperactivation, triggers both insulin secretion and degradation, and increases insulin sensitivity. CELA2A Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 27.9 kDa and the accession number is P08217. |
|
TMPH-02582
|
CELA2A Protein, Mouse, Recombinant (His)
Elastase-2A,ELA2A,CELA2A,Chymotrypsin-like elastase family m...
|
Mouse
|
E. coli
|
|
Elastase that enhances insulin signaling and might have a physiologic role in cellular glucose metabolism. Circulates in plasma and reduces platelet hyperactivation, triggers both insulin secretion and degradation, and increases insulin sensitivity. CELA2A Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 29.7 kDa and the accession number is P05208. |
|
TMPH-02306
|
VTI1B Protein, Human, Recombinant (His & SUMO)
Vti1-rp1,VTI1B,Vesicle transport through interaction with t-...
|
Human
|
E. coli
|
|
V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. May be concerned with increased secretion of cytokines associated with cellular senescence. |
|
TMPH-01093
|
CELA2A Protein, Human, Recombinant (E. coli, His)
Elastase-2A,CELA2A,Chymotrypsin-like elastase family member ...
|
Human
|
E. coli
|
|
Elastase that enhances insulin signaling and might have a physiologic role in cellular glucose metabolism. Circulates in plasma and reduces platelet hyperactivation, triggers both insulin secretion and degradation, and increases insulin sensitivity. CELA2A Protein, Human, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 29.9 kDa and the accession number is P08217. |
|
TMPH-00304
|
SV2A Protein, Bovine, Recombinant (His & Myc)
Synaptic vesicle glycoprotein 2A,p87,SV2A
|
Bovine
|
HEK293 Cells
|
|
Plays a role in the control of regulated secretion in neural and endocrine cells, enhancing selectively low-frequency neurotransmission. Positively regulates vesicle fusion by maintaining the readily releasable pool of secretory vesicles. SV2A Protein, Bovine, Recombinant (His & Myc) is expressed in HEK293 mammalian cells with N-10xHis and C-Myc tag. The predicted molecular weight is 22.8 kDa and the accession number is Q29397. |
|
TMPH-03328
|
Mcpt1 Protein, Rat, Recombinant (Myc)
Mast cell protease I,Mcpt1,Chymase,Mast cell protease 1,Chym...
|
Rat
|
E. coli
|
|
Major secreted protease of mast cells with suspected roles in vasoactive peptide generation, extracellular matrix degradation, and regulation of gland secretion. May participate in generating perivascular beta-protein which ultimately aggregates into amyloid-beta deposits. Mcpt1 Protein, Rat, Recombinant (Myc) is expressed in E. coli expression system with N-Myc tag. The predicted molecular weight is 28.6 kDa and the accession number is P09650. |
|
TMPK-01152
|
CHRDL1 Protein, Human, Recombinant (His)
VOPT,Ventroptin,Neuralin-1,dA141H5.1,CHL,Chordin-like 1,CRDL...
|
Human
|
E. coli
|
|
CHRDL1 (Chordin-like 1) is a secreted protein that acts as an antagonist of bone morphogenetic protein (BMP). BMP plays a role as an activator of BMP receptor II (BMPR II), which mediates extracellular to intracellular signal transmission and is involved in carcinogenesis and metastasis.The hypermethylation of the CHRDL1 promoter in gastric cancer, which induced low expression of CHRDL1 and decreased its secretion to the supernatant. |
|
TMPH-01385
|
GLP1R Protein, Human, Recombinant (His)
Glucagon-like peptide 1 receptor,GLP1R
|
Human
|
HEK293 Cells
|
|
G-protein coupled receptor for glucagon-like peptide 1 (GLP-1). Ligand binding triggers activation of a signaling cascade that leads to the activation of adenylyl cyclase and increased intracellular cAMP levels. Plays a role in regulating insulin secretion in response to GLP-1. GLP1R Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with N-6xHis tag. The predicted molecular weight is 18.3 kDa and the accession number is P43220. |
|
TMPH-03294
|
FGF-23 Protein, Rat, Recombinant (His)
Fibroblast growth factor 23,Fgf23
|
Rat
|
P. pastoris (Yeast)
|
|
Regulator of phosphate homeostasis. Inhibits renal tubular phosphate transport by reducing SLC34A1 levels. Regulator of vitamin-D metabolism. Negatively regulates osteoblasts differentiation and matrix mineralization. Acts directly on the parathyroid to decrease PTH secretion. Upregulates EGR1 expression in the presence of KL. FGF-23 Protein, Rat, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 27.5 kDa and the accession number is Q8VI82. |
|
TMPY-01960
|
Munc18c/STXBP3 Protein, Human, Recombinant (His & GST)
syntaxin binding protein 3,MUNC18C,UNC-18C,MUNC18-3,PSP
|
Human
|
Baculovirus Insect Cells
|
|
Syntaxin-binding protein 3, also known as Platelet Sec1 protein, Protein unc-18 homolog 3, Protein unc-18 homolog C, Unc-18C, Unc18-3 and STXBP3, is a cytoplasm protein which belongs to the STXBP/unc-18/SEC1 family. STXBP3 is expressed in cells that exhibit granule exocytosis, such as neutrophils, mast cells, platelets and endothelial cells. STXBP3, together with STX4 and VAMP2, may play a role in insulin-dependent movement of GLUT4 and in docking / fusion of intracellular GLUT4-containing vesic... |
|
TMPY-02549
|
GBP1 Protein, Human, Recombinant (His)
guanylate binding protein 1,GBP1
|
Human
|
HEK293 Cells
|
|
Guanylate-binding protein 1 (GBP-1) is a member of the GBP family whose members are GTPases induced in response to interferon-λ (IFN-λ), with seven highly homologous members in humans, termed HuGBP-1 to HuGBP-7. GBP-1 expression is induced by type1 and type2 interferons, including IFN-λ and also by interleukin-1β (IL-1β), IL-1α, and tumor necrosis factor-α (TNF-α). GBP-1 is key to the protective immunity against microbial and viral pathogens. GBP-1 was only secreted from endothelial cells. Secre... |
|
TMPH-00317
|
BipD Protein, Burkholderia pseudomallei, Recombinant (His & Myc)
Translocator protein BipD,bipD
|
Burkholderia pseudomallei
|
E. coli
|
|
Required for invasion of epithelial cells, as well as for survival within host cells, escape from endocytic vesicles and subsequent actin-tail formation. Probably regulates the secretion of effectors BipB and BipC and their final integration into the target cell membrane. BipD Protein, Burkholderia pseudomallei, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 41.4 kDa and the accession number is Q3JL26. |
|
TMPH-02676
|
GLP1R Protein, Mouse, Recombinant (His & SUMO)
Glucagon-like peptide 1 receptor,Glp1r
|
Mouse
|
E. coli
|
|
G-protein coupled receptor for glucagon-like peptide 1 (GLP-1). Ligand binding triggers activation of a signaling cascade that leads to the activation of adenylyl cyclase and increased intracellular cAMP levels. Plays a role in regulating insulin secretion in response to GLP-1. GLP1R Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 30.4 kDa and the accession number is O35659. |
|
TMPH-01384
|
GLP1R Protein, Human, Recombinant (E. coli, His)
GLP1R,Glucagon-like peptide 1 receptor
|
Human
|
E. coli
|
|
G-protein coupled receptor for glucagon-like peptide 1 (GLP-1). Ligand binding triggers activation of a signaling cascade that leads to the activation of adenylyl cyclase and increased intracellular cAMP levels. Plays a role in regulating insulin secretion in response to GLP-1. GLP1R Protein, Human, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 18.3 kDa and the accession number is P43220. |
|
TMPH-03301
|
GLP1R Protein, Rat, Recombinant (E. coli, His)
Glp1r,Glucagon-like peptide 1 receptor
|
Rat
|
E. coli
|
|
G-protein coupled receptor for glucagon-like peptide 1 (GLP-1). Ligand binding triggers activation of a signaling cascade that leads to the activation of adenylyl cyclase and increased intracellular cAMP levels. Plays a role in regulating insulin secretion in response to GLP-1. GLP1R Protein, Rat, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 17.1 kDa and the accession number is P32301. |
|
TMPK-00237
|
2B4/CD244 Protein, Human, Recombinant (aa 22-221, His & Avi), Biotinylated
NAIL,CD244,SLAMF4,h2B4,NKR2B4,Nmrk,CD244 antigen,2B4
|
Human
|
HEK293 Cells
|
|
2B4 (CD244) is expressed by memory-phenotype CD8() T cells and all natural killer (NK) cells. The ligand for 2B4, CD48, is expressed on hematopoietic cells. 2B4 is conserved in humans and mice, and a number of reports have linked 2B4 with activation of lymphocytes.Engagement of 2B4 on NK cell surfaces with specific antibodies or CD48 can trigger cell mediated cytotoxicity, interferon γ secretion, phosphoinositol turnover and NK cell invasiveness. |
|
TMPJ-00875
|
NPPB Protein, Human, Recombinant (His)
NPPB,γ-Brain Natriuretic Peptide,Gamma-Brain Natriuretic Pep...
|
Human
|
E. coli
|
|
Human Natriuretic peptides B acts as a cardiac hormone; it is associated with many biological actions, such as diuresis, natriuresis, vasorelaxation, which inhibits the secretion of rennin and aldosterone. It acts as a paracrine antifibrotic factor in the heart. Natriuretic peptides B can help restore the body balance of salt and water, improves the heart function. Natriuretic peptides B binds and stimulates the cGMP production of the NPR1 receptor and binds the clearance receptor NPR3. |
|
TMPH-02677
|
GPI Protein, Mouse, Recombinant (B2M & His)
Gpi,Phosphohexose isomerase,Phosphoglucose isomerase,Neurole...
|
Mouse
|
E. coli
|
|
In the cytoplasm, catalyzes the conversion of glucose-6-phosphate to fructose-6-phosphate, the second step in glycolysis, and the reverse reaction during gluconeogenesis. Besides it's role as a glycolytic enzyme, also acts as a secreted cytokine: acts as an angiogenic factor (AMF) that stimulates endothelial cell motility. Acts as a neurotrophic factor, neuroleukin, for spinal and sensory neurons. It is secreted by lectin-stimulated T-cells and induces immunoglobulin secretion. |
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