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Neticonazole (SS717) 是一种咪唑衍生物,具有抗真菌活性,可抑制外泌体分泌。Neticonazole 具有抗感染和抗癌作用,可诱导接触性皮炎,可用于研究皮肤白色念珠菌感染。
Neticonazole (SS717) 是一种咪唑衍生物,具有抗真菌活性,可抑制外泌体分泌。Neticonazole 具有抗感染和抗癌作用,可诱导接触性皮炎,可用于研究皮肤白色念珠菌感染。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
2 mg | ¥ 176 | 现货 | |
5 mg | ¥ 266 | 现货 | |
1 mL x 10 mM (in DMSO) | ¥ 688 | 现货 |
产品描述 | Neticonazole (SS717) is an imidazole derivative with antifungal activity that inhibits exosome secretion. Neticonazole has anti-infective and anti-cancer effects, can induce contact dermatitis, and can be used to study skin Candida albicans infections. |
靶点活性 | Exosome: |
体外活性 | Neticonazole 针对 39 T. rubrum isolates 菌株(MIC80,0.125 μg/ml)和 28 T. mentagrophytes 菌株(MIC80,0.25 μg/ml)。Neticonazole 可抑制 39 T. rubrum isolates 菌株(MFC80,0.25 μg/ml)和 28 T. mentagrophytes 菌株(MFC80,0.25 μg/ml)。[1] |
体内活性 | 一种临床分离的 C. albicans (分离株 KC-36)被用于豚鼠皮肤念珠菌病的实验。 Neticonazole 对试验菌株的 MIC 值为 0.0625。[1] |
别名 | 奈康唑, SS-717, SS717, SS 717 |
分子量 | 302.43 |
分子式 | C17H22N2OS |
CAS No. | 130726-68-0 |
Smiles | C(=C\SC)(\C1=C(OCCCCC)C=CC=C1)/N2C=CN=C2 |
存储 | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
溶解度信息 | 1M HCl: 80 mg/mL(264.52 mM), when pH is adjusted to 1 with 1M HCl.Sonication is recommended. DMSO: 200 mg/mL(661.31 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
溶液配制表 | ||||||||||||||||||||||||||||||||||||
1M HCl/DMSO
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