|
TMPY-02881
|
RAGE Protein, Human, Recombinant
RAGE,advanced glycosylation end product-specific re...
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Human
|
HEK293 Cells
|
|
RAGE Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 35 kDa and the accession number is A0A1U9X785. |
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TMPY-02927
|
RAGE Protein, Human, Recombinant (His)
RAGE,advanced glycosylation end product-specific re...
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Human
|
HEK293 Cells
|
|
RAGE Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 35.5 kDa and the accession number is A0A1U9X785. |
|
TMPY-01675
|
RAGE Protein, Mouse, Recombinant (His)
advanced glycosylation end product-specific recepto...
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Mouse
|
HEK293 Cells
|
|
RAGE Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 35.3 kDa and the accession number is Q62151-1. |
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TMPY-01716
|
RAGE Protein, Human, Recombinant (hFc)
RAGE,advanced glycosylation end product-specific re...
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Human
|
HEK293 Cells
|
|
RAGE Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61.1 kDa and the accession number is A0A1U9X785. |
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TMPH-00531
|
SSB Protein, Enterobacteria phage T7, Recombinant (His & SUMO)
Single-stranded DNA-binding protein,Gene product 2....
|
Enterobacteria phage T7
|
E. coli
|
|
Single-stranded DNA-binding protein that participates in viral DNA replication, formation of concatemers, recombination and repair of double-stranded breaks. Coats the lagging-strand ssDNA as the replication fork advances and stimulates the activities of viral DNA polymerase and primase/helicase. Coordinates simultaneous synthesis of leading- and lagging-strands. Together with DNA primase/helicase, promotes pairing of two homologous DNA molecules containing complementary single-stranded regions ... |
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TMPH-00532
|
SSB Protein, Enterobacteria phage T7, Recombinant
Gene product 2.5,Single-stranded DNA-binding protei...
|
Enterobacteria phage T7
|
P. pastoris (Yeast)
|
|
Single-stranded DNA-binding protein that participates in viral DNA replication, formation of concatemers, recombination and repair of double-stranded breaks. Coats the lagging-strand ssDNA as the replication fork advances and stimulates the activities of viral DNA polymerase and primase/helicase. Coordinates simultaneous synthesis of leading- and lagging-strands. Together with DNA primase/helicase, promotes pairing of two homologous DNA molecules containing complementary single-stranded regions ... |
|
TMPH-00754
|
Capsid decoration Protein, Escherichia phage lambda, Recombinant (GST)
Gene product D,Auxiliary protein D,Major capsid pro...
|
Escherichia phage lambda
|
E. coli
|
|
Stabilizes the expansion of the capsid head shell after genome packaging. The packaging of viral genome in the procapsid triggers a dramatic reconfiguration of the capsid shell, expanding from roughly 50nm to 60nm while the capsid thickness decreases. 415 capsid decoration protein molecules cooperatively bind the expanded capsid, thereby stabilizing the mature capsid shell. Capsid decoration Protein, Escherichia phage lambda, Recombinant (GST) is expressed in E. coli expression system with N-GST... |
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TMPH-00308
|
ISG15 Protein, Bovine, Recombinant (His)
Interferon-stimulated gene product 17,ISG15,Ubiquit...
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Bovine
|
E. coli
|
|
ISG15 Protein, Bovine, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 21.4 kDa and the accession number is O02741. |
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TMPY-01736
|
COX-2 Protein, Human, Recombinant (His)
GRIPGHS,PHS-2,hCox-2,COX-2,PGHS-2,prostaglandin-endoperoxide...
|
Human
|
Baculovirus Insect Cells
|
|
PTGS2, also known as COX-2, is s component of Prostaglandin-endoperoxide synthase (PTGS). PTGS, also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. PTGS2 is overexpressed in many cancers. The overexpression of PTGS2 along with increased angiogenesis and GLUT-1 expression ... |
|
TMPY-04548
|
CDK4 Protein, Human, Recombinant (GST)
CMM3,PSK-J3,cyclin-dependent kinase 4
|
Human
|
Baculovirus Insect Cells
|
|
CDK4 is a member of the Ser/Thr protein kinase family. It is highly similar to the gene products of S. cerevisiae cdc28 and S. pombe cdc2. It is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression. The activity of CDK4 is restricted to the G1-S phase, which is controlled by the regulatory subunits D-type cyclins and CDK inhibitor p16(INK4a). CDK4 was shown to be responsible for the phosphorylation of retinoblastoma gene product. CDK4 is the ser... |
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TMPH-03605
|
CHOD Protein, Streptomyces sp., Recombinant (GST)
choA,Cholesterol isomerase,CHOD,Cholesterol oxidase
|
Streptomyces
|
E. coli
|
|
Bifunctional enzyme that catalyzes the oxidation of the 3-beta-hydroxy group of cholesterol and the isomerization of the double bond of the resulting product. CHOD Protein, Streptomyces sp., Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 81.9 kDa and the accession number is P12676. |
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TMPK-01251
|
L1R Protein, Monkeypox virus, Recombinant (His)
0
|
Monkeypox virus
|
E. coli
|
|
L1R, a myristylated late gene product of vaccinia virus, is essential for formation of infectious intracellular mature virions (IMV). In its absence, only viral particles arrested at an immature stage are detected and no infectious progeny virus is produced. |
|
TMPH-00626
|
GPR Protein, E. coli, Recombinant (His)
proA,Glutamyl-gamma-semialdehyde dehydrogenase,Gamma-glutamy...
|
E. coli
|
E. coli
|
|
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. GPR Protein, E. coli, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 48.7 kDa and the accession number is P07004. |
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TMPH-01553
|
GBP2 Protein, Human, Recombinant (E. coli, His)
Interferon-induced guanylate-binding protein 2,GBP2,Guanylat...
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Human
|
E. coli
|
|
Hydrolyzes GTP to GMP in 2 consecutive cleavage reactions, but the major reaction product is GDP. Exhibits antiviral activity against influenza virus. Promotes oxidative killing and delivers antimicrobial peptides to autophagolysosomes, providing broad host protection against different pathogen classes. GBP2 Protein, Human, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 22.4 kDa and the accession number is P32456. |
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TMPH-02186
|
TERT Protein, Human, Recombinant (His)
Telomerase reverse transcriptase,Telomerase catalytic subuni...
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Human
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E. coli
|
|
Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-de... |
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TMPK-01087
|
Apolipoprotein A-V/APOA5 Protein, Mouse, Recombinant (His)
ApoA-V,Apolipoprotein A-V,Rap3,Apoa5,Apo-AV,Apolipoprotein A...
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Mouse
|
E. coli
|
|
APOA5 is probably the gene with the strongest effect on triglyceride (TG) metabolism. APOA5 is almost exclusively expressed in the liver, and its product apoAV has a very low circulating concentration. New physiological roles of apoAV have been recently elucidated, such as control of chylomicron production in the intestine and TG accumulation in adipose tissue.The key role of APOA5 in TG metabolism has been largely shown through genetic studies in association with either severe or moderate hyper... |
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TMPH-00917
|
ADH4 Protein, Human, Recombinant (GST)
Alcohol dehydrogenase 4,Alcohol dehydrogenase 2,All-trans-re...
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Human
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E. coli
|
|
Catalyzes the NAD-dependent oxidation of either all-trans-retinol or 9-cis-retinol. Also oxidizes long chain omega-hydroxy fatty acids, such as 20-HETE, producing both the intermediate aldehyde, 20-oxoarachidonate and the end product, a dicarboxylic acid, (5Z,8Z,11Z,14Z)-eicosatetraenedioate. Also catalyzes the reduction of benzoquinones. ADH4 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 67.2 kDa and the accession n... |
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TMPY-03996
|
COLEC10 Protein, Mouse, Recombinant (hFc)
collectin sub-family member 10 (C-type lectin),CL-L1
|
Mouse
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HEK293 Cells
|
|
COLEC1 is a member of the C-lectin family. Members of this family possess collagen-like sequences and carbohydrate recognition domains. The other members of this family are secreted proteins and bind to carbohydrate antigens on microorganisms facilitating their recognition and removal. This gene product is a cytosolic protein, a characteristic that suggests that it may have different biological functions than other C-lectins. COLEC10 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mamma... |
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TMPK-00812
|
Midkine Protein, Mouse, Recombinant (His)
MK1,ARAP,MKARAP,MEK,MK,NEGF2,MDK
|
Mouse
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E. coli
|
|
Midkine is a heparin-binding growth factor, originally reported as the product of a retinoic acid-responsive gene during embryogenesis, but currently viewed as a multifaceted factor contributing to both normal tissue homeostasis and disease development. Midkine is abnormally expressed at high levels in various human malignancies and acts as a mediator for the acquisition of critical hallmarks of cancer, including cell growth, survival, metastasis, migration, and angiogenesis. Midkine Protein, Mo... |
|
TMPK-01395
|
TENM2 Protein, Human, Recombinant (His)
Ten-m2,KIAA1127,Teneurin-2,TNM2,ODZ2,Tenascin-M2,Ten-2
|
Human
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HEK293 Cells
|
|
Teneurin-2 is a member of a novel family of transmembrane proteins characterized to date in fish, birds, mammals, and Drosophila (e.g., the pair-rule gene product Ten-m). Teneurin-2, a vertebrate homologue of the Drosophila pair-rule gene ten-m/odz, is revealed to be a membrane-bound transcription regulator. In the nucleus, the intracellular domain of teneurin-2 colocalizes with promyelocytic leukemia (PML) protein in nuclear bodies implicated in transcription control. |
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TMPH-00692
|
MTA/SAH nucleosidase Protein, E. coli O9:H4, Recombinant (His & Myc)
5'-methylthioadenosine nucleosidase,5'-methylthioadenosine/S...
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E. coli
|
E. coli
|
|
Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine. Thus, is required for in vivo function of the radical SAM enzymes biotin synthase and lipoic acid synthase, that are inhibited b... |
|
TMPH-03702
|
MTA/SAH nucleosidase Protein, Vibrio cholerae serotype O1, Recombinant (His & Myc)
5'-deoxyadenosine nucleosidase,5'-methylthioadenosine nucleo...
|
Vibrio cholerae
|
E. coli
|
|
Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively. Also cleaves 5'-deoxyadenosine, a toxic by-product of radical S-adenosylmethionine (SAM) enzymes, into 5-deoxyribose and adenine. MTA/SAH nucleosidase Protein, Vibrio cholerae serotype O1, Recombinant (His & Myc) is expressed in E. coli expression system wit... |
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TMPK-01285
|
FSHB Protein, Cynomolgus, Recombinant (His)
Follitropin,FSH-B,FSH-beta,FSH-β,FSHB
|
Cynomolgus
|
HEK293 Cells
|
|
Fertility is dependent on follicle-stimulating hormone (FSH), a product of gonadotrope cells of the anterior pituitary gland. Hypothalamic gonadotropin-releasing hormone (GnRH) and intra-pituitary activins are regarded as the primary drivers of FSH synthesis and secretion. Both stimulate expression of the FSH beta subunit gene (Fshb), although the underlying mechanisms of GnRH action are poorly described relative to those of the activins. FSHB Protein, Cynomolgus, Recombinant (His) is expressed ... |
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TMPK-00521
|
PSMA Protein, Cynomolgus, Recombinant (His)
PSMA,FOLHNAALADase I,FGCP,GCPII,PSMAFGCP,NAALADase I,PSM,NAA...
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Cynomolgus
|
HEK293 Cells
|
|
Prostate-specific membrane antigen (PSMA) is an enzyme that in humans is encoded by the FOLH1 (folate hydrolase 1) gene, also known as Glutamate carboxypeptidase II (GCPII). Human PSMA is highly expressed in the prostate, roughly a hundred times greater than in most other tissues. In some prostate cancers, PSMA is the second-most upregulated gene product, with an 8- to 12-fold increase over levels in noncancerous prostate cells. PSMA Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 ... |
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TMPH-02590
|
COL4A2 Protein, Mouse, Recombinant (His)
COL4A2,Collagen alpha-2(IV) chain
|
Mouse
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E. coli
|
|
Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.; Canstatin, a cleavage product corresponding to the collagen alpha 2(IV) NC1 domain, possesses both anti-angiogenic and anti-tumor cell activity. It inhibits proliferation and migration of endothelial cells, reduces mitochondrial membrane potential, and induces apoptosis. Specifically induces Fas-dependent apoptos... |
|
TMPK-00370
|
PSMA Protein, Human, Recombinant (hFc)
NAALAdase,FOLH1,FOLHNAALADase I,FGCP,mGCP,PSMAFGCP,NAALADase...
|
Human
|
HEK293 Cells
|
|
Prostate-specific membrane antigen (PSMA) is an enzyme that in humans is encoded by the FOLH1 (folate hydrolase 1) gene, also known as Glutamate carboxypeptidase II (GCPII). Human PSMA is highly expressed in the prostate, roughly a hundred times greater than in most other tissues. In some prostate cancers, PSMA is the second-most upregulated gene product, with an 8- to 12-fold increase over levels in noncancerous prostate cells. PSMA Protein, Human, Recombinant (hFc) is expressed in HEK293 mamma... |
|
TMPK-01020
|
FSHB Protein, Mouse, Recombinant (hFc)
FSH-beta,FSH-B,FSHB,FSH-β,Follitropin
|
Mouse
|
HEK293 Cells
|
|
Fertility is dependent on follicle-stimulating hormone (FSH), a product of gonadotrope cells of the anterior pituitary gland. Hypothalamic gonadotropin-releasing hormone (GnRH) and intra-pituitary activins are regarded as the primary drivers of FSH synthesis and secretion. Both stimulate expression of the FSH beta subunit gene (Fshb), although the underlying mechanisms of GnRH action are poorly described relative to those of the activins. FSHB Protein, Mouse, Recombinant (hFc) is expressed in HE... |
|
TMPJ-00250
|
LAP (TGF-beta 1) Protein, Human, Recombinant (His & Avi), Biotinylated
transforming growth factor β1,TGFβ,CED,TGFB,TGFbeta,LAP (TGF...
|
Human
|
HEK293 Cells
|
|
Transforming growth factor beta (TGFβ) family members are secreted in inactive complexes with a latency-associated peptide (LAP), a protein derived from the N-terminal region of the TGFβ gene product. Extracellular activation of these complexes is a critical step in regulation of TGFβ function in vivo. The TGFβ1 LAP is a ligand for the integrin αvβ6 and that αvβ6-expressing cells induce spatially restricted activition of TGFβ1. And LAP identifies a novel CD4+/CD25+ regulatory T cell subset with ... |
|
TMPY-04103
|
COLEC10 Protein, Cynomolgus, Recombinant (hFc)
collectin sub-family member 10 (C-type lectin)
|
Cynomolgus
|
HEK293 Cells
|
|
COLEC1 is a member of the C-lectin family. Members of this family possess collagen-like sequences and carbohydrate recognition domains. The other members of this family are secreted proteins and bind to carbohydrate antigens on microorganisms facilitating their recognition and removal. This gene product is a cytosolic protein, a characteristic that suggests that it may have different biological functions than other C-lectins. COLEC10 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 ... |
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TMPK-00371
|
PSMA Protein (Primary Amine Labeling), Mouse, Recombinant (His), Biotinylated
NAALADase I,FOLH1,GCPIImGCP,FGCP,GCP2,PSM,mGCP,NAALAdase,FOL...
|
Mouse
|
HEK293 Cells
|
|
Prostate-specific membrane antigen (PSMA) is an enzyme that in humans is encoded by the FOLH1 (folate hydrolase 1) gene, also known as Glutamate carboxypeptidase II (GCPII). Human PSMA is highly expressed in the prostate, roughly a hundred times greater than in most other tissues. In some prostate cancers, PSMA is the second-most upregulated gene product, with an 8- to 12-fold increase over levels in noncancerous prostate cells. PSMA Protein (Primary Amine Labeling), Mouse, Recombinant (His), Bi... |
|
TMPK-00023
|
Midkine Protein, Human, Recombinant (His & Avi)
MDK,MEK,MK1,MKARAP,ARAP,MK,NEGF2
|
Human
|
E. coli
|
|
Midkine is a heparin-binding growth factor, originally reported as the product of a retinoic acid-responsive gene during embryogenesis, but currently viewed as a multifaceted factor contributing to both normal tissue homeostasis and disease development. Midkine is abnormally expressed at high levels in various human malignancies and acts as a mediator for the acquisition of critical hallmarks of cancer, including cell growth, survival, metastasis, migration, and angiogenesis. Midkine Protein, Hu... |
|
TMPK-00024
|
Midkine Protein, Human, Recombinant (His & Avi), Biotinylated
MK1,MK,MDK,NEGF2,MKARAP,MEK,ARAP
|
Human
|
E. coli
|
|
Midkine is a heparin-binding growth factor, originally reported as the product of a retinoic acid-responsive gene during embryogenesis, but currently viewed as a multifaceted factor contributing to both normal tissue homeostasis and disease development. Midkine is abnormally expressed at high levels in various human malignancies and acts as a mediator for the acquisition of critical hallmarks of cancer, including cell growth, survival, metastasis, migration, and angiogenesis. Midkine Protein, Hu... |
|
TMPK-00522
|
PSMA Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His), Biotinylated
PSMAFGCP,PSM,NAALAdase,NAALADase I,FOLHNAALADase I,GCPIImGCP...
|
Cynomolgus
|
HEK293 Cells
|
|
Prostate-specific membrane antigen (PSMA) is an enzyme that in humans is encoded by the FOLH1 (folate hydrolase 1) gene, also known as Glutamate carboxypeptidase II (GCPII). Human PSMA is highly expressed in the prostate, roughly a hundred times greater than in most other tissues. In some prostate cancers, PSMA is the second-most upregulated gene product, with an 8- to 12-fold increase over levels in noncancerous prostate cells. PSMA Protein (Primary Amine Labeling), Cynomolgus, Recombinant (His... |
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TMPY-03122
|
GBP2 Protein, Human, Recombinant (His)
guanylate binding protein 2,GBP2
|
Human
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HEK293 Cells
|
|
GBP-2 belongs to the guanylate-binding protein (GBP) family. GBPs are characterized by their ability to specifically bind guanine nucleotides (GMP, GDP, and GTP). As GTPases induced by IFN-gamma (Interferon-inducible GTPase), they are key to the protective immunity against microbial and viral pathogens. GBP-2 is a GTPase that converts GTP to GDP and GMP. It binds GTP, GDP and GMP. GBP-2 hydrolyzes GTP very efficiently. GDP rather than GMP is the major reaction product. GBP-2 is induced by interf... |
|
TMPK-00507
|
TREM2 Protein, Cynomolgus, Recombinant (His)
TREM2,Trem2a,PLOSL2,TREM-2,Trem2c,Trem2b
|
Cynomolgus
|
HEK293 Cells
|
|
TREM-2 (Triggering Receptor Expressed on Myeloid cells-2) is a 35 kDa type I transmembrane member of the TREM family and Ig superfamily. Mature human TREM-2 consists of a 156 amino acid (aa) extracellular domain (ECD) with one V-type Ig-like domain, a 21 aa transmembrane (TM) domain, and a 35 aa cytoplasmic tail. TREM-2 forms a receptor signaling complex with TYROBP which mediates signaling and cell activation following ligand binding (PubMed:10799849). Acts as a receptor for amyloid-beta prote... |
|
TMPH-03038
|
Cobra venom factor Protein, Naja kaouthia, Recombinant (His & SUMO)
Cobra venom factor,Complement C3 homolog,CVFk,CVF
|
Naja kaouthia
|
E. coli
|
|
Complement-activating protein in cobra venom. It is a structural and functional analog of complement component C3b, the activated form of C3. It binds factor B (CFB), which is subsequently cleaved by factor D (CFD) to form the bimolecular complex CVF/Bb. CVF/Bb is a C3/C5 convertase that cleaves both complement components C3 and C5. Structurally, it resembles the C3b degradation product C3c, which is not able to form a C3/C5 convertase. Unlike C3b/Bb, CVF/Bb is a stable complex and completely re... |
|
TMPJ-00828
|
Tau-F Protein, Human, Recombinant
Neurofibrillary tangle protein,Paired helical filament-tau,M...
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Human
|
E. coli
|
|
Tau proteins are proteins which contain four Tau/MAP repeats. They promote microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. They are abundant in neurons of the central nervous system and are less common elsewhere, but are also expressed at very low levels in CNS astrocytes and oligodendrocytes. The tau proteins are the product of alternative splicing from a single gene that in humans is designated MAPT. When tau proteins are def... |
|
TMPY-03749
|
LC3B Protein, Human, Recombinant (His)
microtubule-associated protein 1 light chain 3 beta,ATG8F,MA...
|
Human
|
E. coli
|
|
MAP1LC3B (Microtubule Associated Protein 1 Light Chain 3 beta, also known as LC3B) is a Protein Coding gene. The product of this gene is a subunit of neuronal microtubule-associated MAP1A and MAP1B proteins, which are involved in microtubule assembly and important for neurogenesis. LC3B is a member of the MAP1 LC3 family. It is most abundantly expressed in the heart, brain, skeletal muscle, and testis. LC3B is a subunit of the neuronal microtubule and functions in the formation of autophagosomal... |
|
TMPY-02433
|
APE1/APEX1 Protein, Human, Recombinant (His)
APEX,HAP1,APX,APE,APEX nuclease (multifunctional DNA repair ...
|
Human
|
E. coli
|
|
The enzyme is known to be a redox factor (Ref-1) stimulating DNA binding activity of AP-1 binding proteins such as Fos and Jun as well as a multifunctional DNA repair enzyme having 5' AP endonuclease, DNA 3' repair diesterase, 3'-5' exonuclease and DNA 3'-phosphatase activities.Although Apex mRNA was expressed ubiquitously, the levels varied significantly, suggesting organ- or tissue-specific expression of the Apex gene. The highest level was observed in the testis, relatively high levels in the... |
|
TMPY-03851
|
BPIFB1 Protein, Human, Recombinant (His)
LPLUNC1,BPI fold containing family B, member 1,C20orf114
|
Human
|
HEK293 Cells
|
|
BPIFB1, also known as LPLUNC1, belongs to the BPI/LBP/Plunc superfamily, plunc family. BPIFB1 may be involved in the innate immune response to bacterial exposure in the mouth, nasal cavities, and lungs. BPIFB1 is expressed in the upper respiratory tract and oral cavity, which may function in host defence. The expression of BPIF proteins is associated with CF lung disease in humans and mice. It is unclear if this elevation of protein production, which results from phenotypic alteration of the cel... |
|
TMPJ-00480
|
SAA1 Protein, Human, Recombinant (His)
SAA1,SAA,Serum Amyloid A-1 Protein
|
Human
|
E. coli
|
|
Serum Amyloid A1 Protein (SAA1) is an acute phase apolipoprotein reactant that is produced predominantly by hepatocytes and is under the regulation of inflammatory cytokines. SAA is produced mainly in the liver and circulates in low levels in the blood. SAA may play a role in the immune system and facilitate the repair of injured tissues, it also acts as an antibacterial agent, and signals the migration of germ-fighting cells to sites of infection. SAA also functions as an apolipoprotein of the ... |
|
TMPY-04462
|
HK3 Protein, Human, Recombinant (His & GST)
HXK3,HKIII,hexokinase 3 (white cell)
|
Human
|
Baculovirus Insect Cells
|
|
Hexokinase-3, also known as Hexokinase type III, HKIII, and HK3, is a protein that belongs to the hexokinase family. Hexokinase-3 / HK3 is an enzyme that in humans is encoded by the HK2 gene. Hexokinases phosphorylate glucose to produce glucose 6-phosphate, committing glucose to the glycolytic pathway. In mammalian tissues, hexokinase exists as four isoenzymes encoded by distinct genes. These proteins are homologous and are organized in two homologous domains, except for hexokinase type IV which... |
|
TMPY-02496
|
Rad6/UBE2A Protein, Human, Recombinant (His)
UBC2,HHR6A,MRXS30,MRXSN,RAD6A,ubiquitin-conjugating enzyme E...
|
Human
|
E. coli
|
|
Ubiquitin-conjugating enzyme E2 A (also known as HHR6A or UBE2A), encoded by human DNA repair genes HHR6A, belongs to the ubiquitin-conjugating enzymes (E2 enzymes) family and is likely to be involved in postreplication repair and induced mutagenesis. UBE2A is described as a CDK2 substrate. It is the human homologue of the product of the Saccharomyces cerevisiae RAD6 / UBC2 gene, a member of the family of ubiquitin-conjugating enzymes. In vivo, HHR6A phosphorylation peaks during the G2/M phase o... |
|
TMPY-02961
|
PANP/C12orf53 Protein, Human, Recombinant (hFc)
C12orf53,UNQ828/PRO1755,PILR α associated neural protein,PAN...
|
Human
|
HEK293 Cells
|
|
C12orf53 is mainly expressed in adult brain and cerebellum. It also can be detected in fetal brain and virtually no expression in spleen, heart, kidney, liver and dorsal ganglion relative to brain. C12orf53 acts as a ligand for PILRA in neural tissues, where it may be involved in immune regulation. Chromosome 12 encodes over 1,100 genes within 132 million bases. A number of skeletal deformities are linked to chromosome 12 including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Noonan... |
|
TMPY-01661
|
METTL1 Protein, Human, Recombinant (His)
methyltransferase like 1,TRMT8,TRM8,YDL201w,C12orf1
|
Human
|
E. coli
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tRNA (guanine-N(7)-)-methyltransferase, also known as Methyltransferase-like protein 1, tRNA (m7G46)-methyltransferase and METTL1, is a nucleus protein that belongs to the methyltransferase superfamily and TrmB family. METTL1 gene has been identified by its sequence similarity to the yeast ORF YDL21w. The human cDNA and the genomic structure of METTL1 have been analyzed. The transcript contains 1292 nucleotides and codes for a protein of 276 amino acids. The METTL1 gene product shows high sequen... |
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TMPJ-01418
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CSF1R Protein, Cynomolgus, Recombinant (hFc)
M-CSF-R,CSF1R,CSF-1-R,CSF-1 receptor,CSF-1R,Macrophage colon...
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Cynomolgus
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HEK293 Cells
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Macrophage colony-stimulating factor 1 receptor (CSF1R) is a member of the type III subfamily of receptor tyrosine kinases that also includes receptors for SCF and PDGF. These receptors each contain five immunoglobulin-like domains in their extracellular domain (ECD) and a split kinase domain in their intracellular region. CSF1R is expressed primarily on cells of the monocyte/macrophage lineage, dendritic cells, stem cells and in the developing placenta. CSF1 and its receptor (CSF1R, product of ... |
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TMPJ-01419
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CSF1R Protein, Cynomolgus, Recombinant (His)
CSF-1-R,CSF-1 receptor,Proto-oncogene c-Fms,M-CSF-R,Macropha...
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Cynomolgus
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HEK293 Cells
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Macrophage colony-stimulating factor 1 receptor (CSF1R) is a member of the type III subfamily of receptor tyrosine kinases that also includes receptors for SCF and PDGF. These receptors each contain five immunoglobulin-like domains in their extracellular domain (ECD) and a split kinase domain in their intracellular region. CSF1R is expressed primarily on cells of the monocyte/macrophage lineage, dendritic cells, stem cells and in the developing placenta. CSF1 and its receptor (CSF1R, product of ... |
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TMPY-02519
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BLVRB Protein, Human, Recombinant (His)
HEL-S-10,biliverdin reductase B,FLR,BVRB,SDR43U1
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Human
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E. coli
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Biliverdin reductase (hBVR) is a serine/threonine kinase that catalyzes reduction of the heme oxygenase (HO) activity product, biliverdin, to bilirubin. BVR consists of an N-terminal dinucleotide-binding domain (Rossmann-fold) and a C-terminal domain that contains a six-stranded β-sheet that is flanked on one face by several α-helices. The C-terminal and N-terminal domains interact extensively, forming the active site cleft at their interface. Biliverdin reductase (BVR) catalyzes the last step i... |
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TMPY-01711
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Serpin B2 Protein, Human, Recombinant (GST)
PAI,serpin peptidase inhibitor, clade B (ovalbumin), member ...
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Human
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Baculovirus Insect Cells
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Serpins are the largest and most diverse family of serine protease inhibitors which are involved in some fundamental biological processes such as blood coagulation, complement activation, fibrinolysis, angiogenesis, inflammation and tumor suppression and are expressed in a cell-specific manner.SerpinB2, also known as Plasminogen activator inhibitor 2, Placental plasminogen activator inhibitor, Monocyte Arg-serpin, Urokinase inhibitor and PAI2, is a cytoplasm protein that belongs to the serpin fa... |
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TMPY-01270
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PRMT3 Protein, Human, Recombinant (GST)
HRMT1L3,protein arginine methyltransferase 3
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Human
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E. coli
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Protein arginine methyltransferase 3, also known as PRMT3, is one of four type I protein arginine methyltransferases (PRMT) that in humans is encoded by the PRMT3 gene. Methylation of arginine residues is a widespread post-translational modification of proteins catalyzed by a small family of PRMTs. The modification appears to regulate protein functions and interactions that affect gene regulation, signalling and subcellular localization of proteins and nucleic acids. In human cells, the PRMT fam... |
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