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8(S)-HETE is a major lipoxygenase product in PMA-treated murine epidermis. It activates mouse keratinocyte protein kinase C with an IC50 of 100 μM. 8(S)-HETE also activates PPARα selectively at concentrations as low as 0.3 μM. Stereochemical assignment of the (S) enantiomer is based on comparison of chiral HPLC retention times to published results.
8(S)-HETE is a major lipoxygenase product in PMA-treated murine epidermis. It activates mouse keratinocyte protein kinase C with an IC50 of 100 μM. 8(S)-HETE also activates PPARα selectively at concentrations as low as 0.3 μM. Stereochemical assignment of the (S) enantiomer is based on comparison of chiral HPLC retention times to published results.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
25 μg | ¥ 2,660 | 35日内发货 | |
50 μg | ¥ 4,770 | 35日内发货 | |
100 μg | ¥ 8,990 | 35日内发货 |
产品描述 | 8(S)-HETE is a major lipoxygenase product in PMA-treated murine epidermis. It activates mouse keratinocyte protein kinase C with an IC50 of 100 μM. 8(S)-HETE also activates PPARα selectively at concentrations as low as 0.3 μM. Stereochemical assignment of the (S) enantiomer is based on comparison of chiral HPLC retention times to published results. |
分子量 | 320.47 |
分子式 | C20H32O3 |
CAS No. | 98462-03-4 |
密度 | 0.984g/cm3 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
溶解度信息 | 0.1 M Na2CO3: 2 mg/mL PBS (pH 7.2): 0.8 mg/mL DMSO: Miscible DMF: Miscible Ethanol: Miscible |
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