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291

抑制剂 & 化合物

185

天然产物

3

化合物库

231

重组蛋白

5

同位素标记化合物

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Cat. No.	Product Name
L1510	核受体化合物库		531 compounds
	531 个核受体作用化合物的独特集合，可用于高通量筛选和高内涵筛选；
L1200	表观遗传库		953 compounds
	953 种表观遗传学研究相关的生物活性小分子的特有集合，用于表观遗传学研究及其相关的检测和高通量、高内涵筛选；
L3800	NF-κB 通路分子库		729 compounds
	729 个 NF-κB 信号通路相关的小分子化合物的特有集合，用于高通量、高内涵筛选；

化合物库

核受体化合物库

Cat.No: L1510

Compounds: 531

表观遗传库

Cat.No: L1200

Compounds: 953

NF-κB 通路分子库

Cat.No: L3800

Compounds: 729

Cat. No.	Product Name	Target	Signaling Pathways
TP1781	Nuclear pore complex protein Nup98 315-360
	Nuclear pore complex protein Nup98 (315-360) is the 315-360 fragment part of the nuclear pore complex (NPC) protein.
T19041	Hoechst S 769121 Nuclear yellow	Others	Others
	Hoechst S 769121 (Nuclear yellow) is a fluorescence dye that can bound to DNA (excitation/emission maxima ~335/495 nm).
T19042	NucPE1 Nuclear Peroxy Emerald 1	Others	Others
	NucPE1, a nuclear-localized fluorescent hydrogen peroxide, is specifically localized to cellular nuclei without appended targeting moieties.
TQ0305	CID-2858522	NF-κB	NF-κB
	CID-2858522 是有效的、选择性抗原受体介导的NF-κB 抑制剂，IC50为 70 nM。
T3954	Adelmidrol	NF-κB; COX; PPAR	DNA Damage/DNA Repair; Immunology/Inflammation; Metabolism; Neuroscience; NF-κB
	Adelmidrol 是壬二酸的抗炎乙醇酰胺衍生物，有抗炎作用，部分与 PPARγ有关。它降低 NF-κB 易位，和 COX-2表达。
T83727	Tat-NTS Peptide TFA Tat-Nuclear Translocation Signal Peptide
	Tat-NTS肽是一种能穿透细胞的肽，由HIV-1 Tat蛋白的转导域与对应于脂联素A1重复III域残基228-237的10个氨基酸肽链接而成，扮演核转运信号（NTS）的角色。它通过阻断脂联素A1与进口素β之间的蛋白质-蛋白质相互作用，阻止脂联素A1在初级鼠海马神经元中的核内转运。Tat-NTS抑制初级鼠海马神经元在葡萄糖-氧剥夺及再灌注诱导的细胞凋亡。在体内，Tat-NTS（10 mg/kg）有效减少了由中脑动脉闭塞（MCAO）引起的缺血-再灌注损伤模型小鼠的梗塞体积和神经元凋亡，并缩短了在Morris水迷宫测试中达到平台的时间。
T16290	NIK SMI1	NF-κB	NF-κB
	NIK SMI1 是 NF-κB 诱导激酶 (NIK) 的选择性抑制剂，能够抑制 NIK 催化的 ATP 水解为 ADP，IC50=0.23±0.17 nM。
T1930	JSH-23	NF-κB	NF-κB
	JSH-23 是NF-κB 抑制剂，作用于脂多糖刺激的巨噬细胞 RAW 264.7，抑制 NF-κB 转录活性(IC50=7.1 μM)，抑制 NF-κB p65 的核易位而不影响 IκBα 降解。
T6661	SC75741	Influenza Virus; NF-κB	Microbiology/Virology; NF-κB
	SC75741 是NF-κB 抑制剂，对p65的IC50为 200 nM。它可阻断流感病毒复制。它通过损害NF-κB 亚基 p65 的 DNA 结合，导致细胞因子，趋化因子和促凋亡因子的表达降低，抑制 caspase 活化和阻断 caspase 介导的病毒核糖核蛋白的核输出。
T83894	4A7C-301-Nurr1 Agonist 4A7C-301-Nuclear Receptor-Related 1
	4A7C-301-Nurr1激动剂是一种核受体相关1（Nurr1）的激动剂。它通过与Nurr1配体结合域（LBD；IC50 = 48.22 nM）结合，增加了在使用SK-N-BE(2)C人神经母细胞瘤细胞进行的报告基因测定中Nurr1-LBD和全长Nurr1的转录活性（EC50s = 6.53 和 50-70 µM，分别）。每天5 mg/kg的4A7C-301-Nurr1激动剂能减少在经MPTP神经毒素或α-突触核蛋白过表达诱导的帕金森病鼠模型中纹状体和黑质compacta部分多巴胺能细胞的死亡，并减少运动和嗅觉缺陷，而不诱发类似运动障碍的行为。
T9917	Denosumab	RANKL/RANK	NF-κB
	Denosumab 是能够结合并抑制RANKL 受体激活因子的人单克隆抗体。它具有抗癌活性，可降髋部、低椎骨以及非椎骨骨折的风险。
T16706	Quinoclamine 灭藻醌,2-氨基-3-氯-1,4-萘醌	NF-κB	NF-κB
	Quinoclamine 是一种 NF-κB 抑制剂，是一种萘醌衍生物，具有抗肿瘤活性。
T8981	WAY-169916 WAY 169916,WAY169916	NF-κB	NF-κB
	WAY-169916 是雌激素受体 (ER) 的通路选择性抑制剂。它通过抑制 NF-kB 转录活性而发挥作用，但没有常规的雌激素活性。
T13604	CDDO-dhTFEA	Others; NF-κB; Nrf2	Immunology/Inflammation; NF-κB; Others
	CDDO-dhTFEA 是合成的齐墩果烷三萜化合物，可有效激活Nrf2并抑制促炎转录因子NF-κB。它可以恢复高血压 (MAP)，提高 Nrf2 及其靶基因的表达，抑制 NF-κB 的活化和转化生长因子-β 途径，并减少慢性肾病 (CKD) 大鼠的肾小球硬化，间质纤维化和炎症。
T22115	SM-7368	NF-κB	NF-κB
	NF-κB Activation Inhibitor III 是一种NF-kB 抑制剂，抑制 TNF-α 诱导的MMP-9上调，靶向抑制下游的MAPK p38，可用于靶向 TNF-α 介导的肿瘤侵袭和转移的化疗研究。
TD0099	Malachite green oxalate	Apoptosis; Others; IκB/IKK; NF-κB	Apoptosis; NF-κB; Others
	Malachite green oxalate 是一种三苯基甲烷染料，可用于检测酶促反应中磷酸盐的释放。它也是一种选择性IKBKE 抑制剂，在体内外均表现出抗肿瘤活性。
T10981	DCZ0415	Apoptosis; Others; NF-κB	Apoptosis; NF-κB; Others
	DCZ0415 在体外、体内和耐药性骨髓瘤患者的原代细胞中诱导抗骨髓瘤活性。它是一种 TRIP13 抑制剂，可损害非同源末端连接的修复并抑制 NF-κB 活性。
T19853	Dimethoxycurcumin Veratrylcurcuminoid,二甲氧基姜黄素	Others	Others
	Dimethoxycurcumin (Veratrylcurcuminoid) 是 curcumin 衍生物，拥有抗氧化及抗炎作用。
T1934	Bay 11-7085 BAY 11-7083	Apoptosis; IκB/IKK; Ferroptosis; NF-κB	Apoptosis; NF-κB
	Bay 11-7085 抑制NF-κB 激活和IκBα磷酸化，其稳定 IκBα 的IC50值为 10 μM。
T6027	Delanzomib 德兰佐米,CEP-18770	Apoptosis; NF-κB; Proteasome	Apoptosis; NF-κB; Proteases/Proteasome; Ubiquitination
	Delanzomib (CEP-18770) 是一种强效的具有口服活性的蛋白酶体的胰凝乳蛋白酶样活性抑制剂，IC50为 3.8 nM。它抑制NF-κB 活性，诱导癌细胞凋亡，具有很强的抗血管生成和抗癌活性。
T8550	NDMC101	Others; NF-κB; Proteasome	NF-κB; Others; Proteases/Proteasome; Ubiquitination
	NDMC101 是有效的破骨细胞形成抑制剂，通过下调 NFATc1 调控基因表达抑制破骨细胞分化。它与 DPP4底物相似，通过抑制DPP4抑制早期 T 细胞激活。它能够用于骨疾病的研究，如类风湿关节炎、滑膜炎等。
T0907	Sulfasalazine 柳氮磺吡啶,NSC 667219,Azulfidine	Apoptosis; Ferroptosis; NF-κB; COX; Antibacterial; Antibiotic; Autophagy	Apoptosis; Autophagy; Immunology/Inflammation; Microbiology/Virology; Neuroscience; NF-κB
	Sulfasalazine (Azulfidine) 是一种合成的水杨酸衍生物，对含有弹性蛋白的结缔组织具有亲和力，并配制成前药。
T1229	Erdosteine 厄多司坦,RV 144,KW-9144	NF-κB; Antibacterial; Adenosine deaminase	Metabolism; Microbiology/Virology; NF-κB
	Erdosteine (RV 144) 抑制脂多糖诱导的NF-κB 激活，具有粘液调节、抗菌、抗炎、抗氧化和自由基清除作用。
T6204	QNZ CAY10470,EVP4593	TNF; NF-κB	Apoptosis; NF-κB
	QNZ (EVP4593) 是 NF-κB 活化和 TNF-α 产生的一种有效抑制剂。 QNZ 对 NF-κB 和 TNF-α 的 IC50 分别为 11 nM 和 7 nM。
T6454	CORM-3 CORM3,(OC-6-44)-三羰基氯(甘氨酸基)钌	Others; NF-κB; NOD-like Receptor (NLR)	Immunology/Inflammation; NF-κB; Others
	CORM-3 是一种 CO 释放分子，能够减少 NLRP3炎症小体的激活，可以减弱 NF-κB p65的核异位，减少 ROS 的生成，并提高细胞内谷胱甘肽和超氧化物歧化酶的水平。
T8799	(E/Z)-IT-603 IT603	Others; NF-κB	NF-κB; Others
	(E/Z)-IT-603 是一种c-Rel 抑制剂，其IC50=3 μM。它是 E-IT-603 和 Z-IT-603的混合物。它具有抗癌作用。它有望作为调节剂调节移植物抗宿主病和恶性病中的 T 细胞反应。
T17217	Vamorolone 地塞米松EP杂质E,VBP15	Glucocorticoid Receptor; NF-κB	Endocrinology/Hormones; NF-κB
	Vamorolone (VBP15) 是一种首创的，具有口服活性的解离性类固醇 (dissociative steroidal) 抗炎药和膜稳定剂。它抑制 (NF-κB) 抑制作用，并降低了激素的影响。它改善肌营养不良，无副作用。
T39924	NF-κΒ activator 2	NF-κB	NF-κB
	NF-κΒ activator 2 是口服有效的 NF-ҡB 激活剂，EC50为 1.58 μM。它通过增加 NF-κB 的表达和激活来诱导 SOD2。它具有用于研究肌萎缩性侧索硬化症的价值。
T1144L	Lidocaine Hydrochloride hydrate	EGFR; Sodium Channel	Angiogenesis; JAK/STAT signaling; Membrane transporter/Ion channel; Tyrosine Kinase/Adaptors
	Lidocaine Hydrochloride hydrate 是一种酰胺类局部麻醉剂，具有抗炎作用。
T8858	DTHIB	HSP	Cytoskeletal Signaling; Metabolism
	DTHIB 是一种选择性热休克蛋白 1 的直接抑制剂，与 HSF1 DNA 结合域结合的Kd 为 160 nM。它选择性刺激核HSF1的降解，强烈抑制 HSF1 癌症基因特征和前列腺癌细胞增殖。
T7511	Cyclo(his-pro)	NF-κB; Endogenous Metabolite	Metabolism; NF-κB
	Cyclo(his-pro) 是一种口服具有活力的，结构上与促甲状腺激素释放激素相关的环状二肽。它能够抑制NF-κB 核积累，也能够穿越脑血屏障并影响多种炎症和应激反应。
T4564	Ethacrynic acid Edecrin,利尿酸,Etacrynic Acid,Hydromedin	Others; Calcium Channel; NF-κB; GST	Membrane transporter/Ion channel; Metabolism; NF-κB; Others; oxidation-reduction
	Ethacrynic acid (Edecrin) 是谷胱甘肽 S-转移酶抑制剂，也是NF-κB 信号传导途径的有效抑制剂，并且还调节白三烯的形成。它还可抑制 L 型电压依赖性和储存操作的钙通道，从而导致气道平滑肌细胞松弛。它是利尿剂，具有抗炎特性，可减轻类维生素 A 诱导的小鼠耳部水肿。
T0468	Lidocaine Lignocaine,Alphacaine,Xylocaine,利多卡因	Apoptosis; ERK; NF-κB; MEK; Sodium Channel; Histamine Receptor	Apoptosis; GPCR/G Protein; Immunology/Inflammation; MAPK; Membrane transporter/Ion channel; Neuroscience; NF-κB
	Lidocaine (Alphacaine) 是一种酰胺衍生物，抑制涉及复杂电压和依赖性的钠通道，可用于研究室性心律失常。它通过调节 miR-145 表达和进一步抑制 MEK/ERK 和 NF-κB 信号通路来减少胃癌细胞的生长，迁移和侵袭。
T6941	PI-1840 PI 1840	PARP; Proteasome	Chromatin/Epigenetic; DNA Damage/DNA Repair; Proteases/Proteasome; Ubiquitination
	PI-1840 是一种高效的、选择性的蛋白酶体chymotrypsin-like (CT-L)抑制剂，IC50=27nM。
T0708	Oxaprozin 奥沙普秦,Oxaprozinum,Wy21743	NF-κB; COX	Immunology/Inflammation; Neuroscience; NF-κB
	Oxaprozin (Oxaprozinum) 是 COX-1和 COX-2的抑制剂，还能抑制 NF-κB 的活化，对人类血小板 COX-1 和 IL-1 刺激的人类滑膜细胞 COX-2 的 IC50值分别为 2.2 和 36 μM。
T6561	Laquinimod LAQ,ABR-215062,拉喹莫德	Apoptosis; Others; NF-κB	Apoptosis; NF-κB; Others
	Laquinimod (LAQ) 是一种免疫调节剂，可预防中枢神经系统的神经变性和炎症。
T22062	CCG-100602	Rho; Ras	Cell Cycle/Checkpoint; GPCR/G Protein; MAPK
	CCG-100602 是心肌蛋白相关转录因子 A/血清反应因子信号转导的特异性抑制剂。它抑制 PC-3 前列腺癌细胞中 RhoA/C 介导的、SRF 驱动的荧光素酶表达，IC50为 9.8 µM。
T0005	Aspirin 阿司匹林,Acetylsalicylate,Acetylsalicylic Acid,邻乙酰水杨酸,ASA	Mitophagy; Virus Protease; COX; Autophagy	Autophagy; Immunology/Inflammation; Microbiology/Virology; Neuroscience
	Aspirin (Acetylsalicylic Acid) 是一种选择性 COX 抑制剂，具有多种药理活性。它是组蛋白去乙酰化酶抑制剂，可上调细胞周期阻滞蛋白 p21，抑制携带 COX-1 的卵巢 Y 细胞。它还抑制 HUVEC 和新生大鼠心室心肌细胞中 COX-2 的表达，分别减少 PG 的产生和 ERK 和 NF-KB 的下调。
T16974	TAK-243 MLN7243	Apoptosis; E1/E2/E3 Enzyme; NF-κB	Apoptosis; NF-κB; Ubiquitination
	TAK-243 (MLN7243) 是一种泛素激活酶 UAE 的抑制剂 (IC50=1 nM)，具有选择性。TAK-243 可阻断泛素结合，破坏单泛素信号传导以及整体蛋白质泛素化。TAK-243 具有抗肿瘤活性，可以促进细胞凋亡。
T0304	Methylthiouracil 甲基硫脲嘧啶,甲硫氧嘧啶,NSC-193526,NSC-9378,MTU	ERK; Antiviral; TNF; NF-κB; Interleukin	Apoptosis; Immunology/Inflammation; MAPK; NF-κB
	Methylthiouracil (NSC-193526) 是一种抗甲状腺剂。它抑制TNF-α和IL-6的产生以及NF-κB 和ERK1/2的活化。
T6495	EUK-134 EUK 134,乙基双亚氨基甲基愈创木酚锰氯化物	Beta Amyloid	Neuroscience
	EUK-134 是合成的超氧化物歧化酶和过氧化氢酶模拟物，可保护大鼠肾脏免受缺血再灌注引起的损伤。它作用于 H9C2 细胞，降低NF-κB 表达、MDA 水平和蛋白质羰基化。它是具有过氧化氢酶活性的超氧化物歧化酶 (SOD) 模拟物 (SODm)。它是保护有丝分裂的抗氧化剂。
T28362	PF-02413873 PF02413873	Progesterone Receptor	Others
	PF-02413873 是一种非甾体孕酮受体的竞争性拮抗剂，Ki 为 2.6 nM。 PF-02413873 可用于治疗子宫内膜异位症等妇科疾病的研究。
T6207	SC144	Apoptosis; Interleukin	Apoptosis; Immunology/Inflammation
	SC144 是一种口服活性 gp130 抑制剂。它结合 gp130，诱导 gp130 磷酸化(S782) 和去糖基化，消除 Stat3 磷酸化和核易位，进一步抑制下游靶基因的表达。它对 gp130 配体触发的信号转导有明显的抑制作用，可诱导人卵巢癌细胞凋亡。
T4400	DIM-C-pPhOH CDIM8	Apoptosis; Others	Apoptosis; Others
	DIM-C-pPhOH (CDIM8) 是一种核受体 4A1(NR4A1) 拮抗剂，可降低细胞增殖，对 ACHN 细胞和 786-O 细胞的IC50值分别为 13.6 μM 和 13.0 μM。它抑制癌细胞的生长和 mTOR 信号传导，诱导细胞凋亡和细胞应激。
T9010	IMM-H007	Others; AMPK	Chromatin/Epigenetic; Others; PI3K/Akt/mTOR signaling
	IMM-H007 是一种新型降脂剂，可增加 abca1 蛋白的表达。
T1144	Lidocaine hydrochloride Lidocaine HCL,盐酸利多卡因,Lignocaine hydrochloride,Xyloneural,Lidothesin	Apoptosis; ERK; NF-κB; MEK; Sodium Channel	Apoptosis; MAPK; Membrane transporter/Ion channel; NF-κB
	Lidocaine hydrochloride (Lignocaine hydrochloride) 抑制涉及复杂电压和依赖性的钠通道。它通过调节 miR-145 表达和进一步抑制 MEK/ERK 和 NF-κB 信号通路来减少胃癌细胞的生长，迁移和侵袭。Lidocaine 是一种酰胺衍生物，是一种研究室性心律失常的药物和有效的肿瘤抑制剂。
T2131	Articaine hydrochloride Ultracaine,盐酸阿替卡因,阿替卡因,Articaine HCl,Hoe-045	Sodium Channel	Membrane transporter/Ion channel
	Articaine hydrochloride (Hoe-045) 一种牙科局部麻醉剂。
T0459	Sulindac Arthrocine,MK-231,舒林酸,Clinoril,Sulindac sulfoxide	COX; Autophagy	Autophagy; Immunology/Inflammation; Neuroscience
	Sulindac (Sulindac sulfoxide) 是一种非甾体类抗炎剂，可抑制COX-2的活性，也可抑制 COX-2 的过表达。它是一种亚磺酰基茚衍生物前药，具有潜在的抗肿瘤活性。
T25465	GS143 GS-143,GS 143	IκB/IKK; E1/E2/E3 Enzyme; NF-κB	NF-κB; Ubiquitination
	GS-143 是选择性的IκBα泛素化抑制剂，抑制 SCFβTrCP1介导的IκBα泛素化作用，IC50=5.2 μM。GS143 抑制NF-κB 的活化和靶基因的转录，并且不抑制蛋白酶体的特性，并具有抗哮喘作用。
T7904	SR 19881	Estrogen/progestogen Receptor	Endocrinology/Hormones
	SR 19881 是 ERRγ 的完全激动剂（结合试验中的 EC50 值为 0.39 μM，基于细胞的试验中 EC50 值为 4.7 μM）。

化合物

Nuclear pore complex protein Nup98 315-360

Cat.No: TP1781

Hoechst S 769121

Cat.No: T19041

Synonym: Nuclear yellow

Target: Others

Cat.No: T19042

Synonym: Nuclear Peroxy Emerald 1

Target: Others

Cat.No: TQ0305

Target: NF-κB

Cat.No: T3954

Target: NF-κB, COX, PPAR

Tat-NTS Peptide TFA

Cat.No: T83727

Synonym: Tat-Nuclear Translocation Signal Peptide

Cat.No: T16290

Target: NF-κB

Cat.No: T1930

Target: NF-κB

Cat.No: T6661

Target: Influenza Virus, NF-κB

4A7C-301-Nurr1 Agonist

Cat.No: T83894

Synonym: 4A7C-301-Nuclear Receptor-Related 1

Cat.No: T9917

Target: RANKL/RANK

Cat.No: T16706

Synonym: 灭藻醌,2-氨基-3-氯-1,4-萘醌

Target: NF-κB

Cat.No: T8981

Synonym: WAY 169916,WAY169916

Target: NF-κB

Cat.No: T13604

Target: Others, NF-κB, Nrf2

Cat.No: T22115

Target: NF-κB

Malachite green oxalate

Cat.No: TD0099

Target: Apoptosis, Others, IκB/IKK, NF-κB

Cat.No: T10981

Target: Apoptosis, Others, NF-κB

Dimethoxycurcumin

Cat.No: T19853

Synonym: Veratrylcurcuminoid,二甲氧基姜黄素

Target: Others

Cat.No: T1934

Synonym: BAY 11-7083

Target: Apoptosis, IκB/IKK, Ferroptosis, NF-κB

Cat.No: T6027

Synonym: 德兰佐米,CEP-18770

Target: Apoptosis, NF-κB, Proteasome

Cat.No: T8550

Target: Others, NF-κB, Proteasome

Cat.No: T0907

Synonym: 柳氮磺吡啶,NSC 667219,Azulfidine

Target: Apoptosis, Ferroptosis, NF-κB, COX, Antibacterial, Antibiotic, Autophagy

Cat.No: T1229

Synonym: 厄多司坦,RV 144,KW-9144

Target: NF-κB, Antibacterial, Adenosine deaminase

Cat.No: T6204

Synonym: CAY10470,EVP4593

Target: TNF, NF-κB

Cat.No: T6454

Synonym: CORM3,(OC-6-44)-三羰基氯(甘氨酸基)钌

Target: Others, NF-κB, NOD-like Receptor (NLR)

Cat.No: T8799

Synonym: IT603

Target: Others, NF-κB

Cat.No: T17217

Synonym: 地塞米松EP杂质E,VBP15

Target: Glucocorticoid Receptor, NF-κB

NF-κΒ activator 2

Cat.No: T39924

Target: NF-κB

Lidocaine Hydrochloride hydrate

Cat.No: T1144L

Target: EGFR, Sodium Channel

Cat.No: T8858

Target: HSP

Cat.No: T7511

Target: NF-κB, Endogenous Metabolite

Ethacrynic acid

Cat.No: T4564

Synonym: Edecrin,利尿酸,Etacrynic Acid,Hydromedin

Target: Others, Calcium Channel, NF-κB, GST

Cat.No: T0468

Synonym: Lignocaine,Alphacaine,Xylocaine,利多卡因

Target: Apoptosis, ERK, NF-κB, MEK, Sodium Channel, Histamine Receptor

Cat.No: T6941

Synonym: PI 1840

Target: PARP, Proteasome

Cat.No: T0708

Synonym: 奥沙普秦,Oxaprozinum,Wy21743

Target: NF-κB, COX

Cat.No: T6561

Synonym: LAQ,ABR-215062,拉喹莫德

Target: Apoptosis, Others, NF-κB

Cat.No: T22062

Target: Rho, Ras

Cat.No: T0005

Synonym: 阿司匹林,Acetylsalicylate,Acetylsalicylic Acid,邻乙酰水杨酸,ASA

Target: Mitophagy, Virus Protease, COX, Autophagy

Cat.No: T16974

Synonym: MLN7243

Target: Apoptosis, E1/E2/E3 Enzyme, NF-κB

Methylthiouracil

Cat.No: T0304

Synonym: 甲基硫脲嘧啶,甲硫氧嘧啶,NSC-193526,NSC-9378,MTU

Target: ERK, Antiviral, TNF, NF-κB, Interleukin

Cat.No: T6495

Synonym: EUK 134,乙基双亚氨基甲基愈创木酚锰氯化物

Target: Beta Amyloid

Cat.No: T28362

Synonym: PF02413873

Target: Progesterone Receptor

Cat.No: T6207

Target: Apoptosis, Interleukin

Cat.No: T4400

Synonym: CDIM8

Target: Apoptosis, Others

Cat.No: T9010

Target: Others, AMPK

Lidocaine hydrochloride

Cat.No: T1144

Synonym: Lidocaine HCL,盐酸利多卡因,Lignocaine hydrochloride,Xyloneural,Lidothesin

Target: Apoptosis, ERK, NF-κB, MEK, Sodium Channel

Articaine hydrochloride

Cat.No: T2131

Synonym: Ultracaine,盐酸阿替卡因,阿替卡因,Articaine HCl,Hoe-045

Target: Sodium Channel

Cat.No: T0459

Synonym: Arthrocine,MK-231,舒林酸,Clinoril,Sulindac sulfoxide

Target: COX, Autophagy

Cat.No: T25465

Synonym: GS-143,GS 143

Target: IκB/IKK, E1/E2/E3 Enzyme, NF-κB

Cat.No: T7904

Target: Estrogen/progestogen Receptor

Cat. No.	Product Name	Target	Signaling Pathways
T5688	Micheliolide	NOS; NF-κB; COX	Immunology/Inflammation; Neuroscience; NF-κB
	Micheliolide 是一种倍半萜内酯，能够抑制各种炎症反应。它能减弱高糖刺激的NF-κB 活化，IκBα的降解，和MCP-1，TGF-β1，FN 在鼠系膜细胞的表达。
TN1131	Handelin	NF-κB; Immunology/Inflammation related	Immunology/Inflammation; NF-κB
	Handelin 是一种来自 Chrysanthemum boreale 的愈创木酚内酯二聚体，它能够阻碍 NF-κB 活化和促炎细胞因子产生，具有抗炎作用。
T13686	Ergolide	NF-κB	NF-κB
	Ergolide, 源自Inula Britannica干燥花朵提取的倍半萜内酯，有效抑制RAW 264.7巨噬细胞中可诱导型一氧化氮合酶(iNOS)和环氧化酶-2(COX-2)的表达，其机制为失活NF-κB。
T4S1540	Myrislignan	Apoptosis; NF-κB	Apoptosis; NF-κB
	Myrislignan 是一种木酚素，从Myristica fragransHoutt 分离得到，具有抗炎作用。它通过抑制NF-kB 信号通路的激活，减轻LPS 诱导的小鼠巨噬细胞炎症反应。
T10383	Asatone	NF-κB	NF-κB
	Asatone 是一种从细辛中分离到的活性成分，通过活化 NF-κB 及下调 p-MAPK (ERK，JNK 和 p38) 通路起作用，具有抗炎作用。
TMA0507	Tomatidine	NF-κB; JNK; Autophagy	Autophagy; MAPK; NF-κB
	Tomatidine 通过阻断 NF-κB 和 JNK 信号传导而发挥抗炎作用。它在哺乳动物细胞或秀丽隐杆线虫中激活自噬。
T3S0807	Berbamine	CaMK; NF-κB; Autophagy	Autophagy; Neuroscience; NF-κB
	Berbamine 是从黄柏中提取的一种天然产物，是钙通道阻滞剂，具有抗肿瘤、免疫调节和心血管作用。
T16324	Nimbolide	Apoptosis; NF-κB; CDK	Apoptosis; Cell Cycle/Checkpoint; NF-κB
	Nimbolide 是源自印楝叶和花的一种三萜。它抑制CDK4/CDK6激酶活性。它抑制 NF-κB，Wnt，PI3K-Akt，MAPK 和 JAK-STAT 信号通路。它通过抑制NF-κB 而诱导肿瘤细胞凋亡。
T5795	Suberosin 软木花椒素	Others; NF-κB	NF-κB; Others
	Suberosin 可分离自Plumbago zeylanica 中，通过调节NF-AT 和NF-κB，抑制PHA-诱导的 PBMC 细胞增殖并捕获细胞周期G1过渡到 S 期，具有抗炎和抗血凝的活性。
T3S1707	Dendrophenol Moscatilin	NF-κB	NF-κB
	Dendrophenol (Moscatilin) 是从石斛茎中分离出来的天然产物，可作为 NF-κB 抑制剂。它有抗肿瘤活性。
T3251	Stachydrine Hydrochloride	NF-κB	NF-κB
	Stachydrine hydrochloride 是Herba Leonuri 的主要活性成分，可以抑制NF-κB 信号通路。它可用于心血管疾病的研究，具有抗心肌肥大活性。
T3S1641	Esculentoside H	TNF; NF-κB; JNK	Apoptosis; MAPK; NF-κB
	Esculentoside H 是一种皂苷，分离自多年生植物 Phytolacca esculent 的根提取物中，具有抗肿瘤作用。它的机制与 TNF 释放能力有关。它能够阻断 JNK1/2和 NF-κB 信号介导的基质金属蛋白酶-9 (MMP-9) 表达，抑制结肠癌细胞迁移。
T4S0800	Demethyleneberberine	P450; NOS; NF-κB; HIF; AMPK	Angiogenesis; Chromatin/Epigenetic; Immunology/Inflammation; Metabolism; NF-κB; PI3K/Akt/mTOR signaling
	Demethyleneberberine 是从黄连中提取的一种天然产物，是线粒体靶向抗氧化剂。它也可作为AMPK 激活剂，用于非酒精性脂肪性肝病的研究。它通过抑制NF-κB 通路和调节 Th 细胞的平衡来减轻小鼠结肠炎并抑制炎症反应。
T6S0119	Dauricine 蝙蝠葛碱	Apoptosis; Others; NF-κB	Apoptosis; NF-κB; Others
	Dauricine 是存在于北豆根粉末中的一种双苯异喹啉生物碱，具有抗炎活性。它通过抑制NF-κB 激活，剂量依赖性地抑制结肠癌细胞的增值和侵袭，并诱导凋亡。
T5S2129	Sciadopitysin	TNF; NF-κB	Apoptosis; NF-κB
	Sciadopitysin 是一种双黄酮类化合物，来自银杏叶片中。它通过抑制NF-κB 活化并降低c-Fos 和NFATc1的表达来抑制 RANKL 诱导的破骨细胞生成和骨丢失。
T11060	DMAPT Dimethylamino Parthenolide	NF-κB	NF-κB
	DMAPT (Dimethylamino Parthenolide) 是一种具有口服活性的NF-κB 抑制剂，是一种 Parthenolide (PTL) 的类似物，对原发性急性髓性白血病细胞的LD50值为1.7 μM。具有潜在的抗肿瘤和抗转移作用。
TN2008	Okanin	NF-κB; TLR	Immunology/Inflammation; NF-κB
	Okanin 是鬼针草中的一种有效成分，可通过抑制TLR4/NF-κB 信号通路减弱 LPS 诱导的小胶质细胞活化。
T3877	Esculentoside A	NF-κB; COX	Immunology/Inflammation; Neuroscience; NF-κB
	Esculentoside A 是一种三萜皂苷，从商陆根部分离得到。它在具有抗炎活性，对环氧合酶-2 具有选择性抑制活性。它通过抑制NF-κB 和丝裂原活化蛋白激酶信号通路抑制 LPS 诱导的急性肺损伤中的炎症反应。
T3913	Saikosaponin D	Estrogen Receptor/ERR; NF-κB; Antibacterial; STAT	Endocrinology/Hormones; JAK/STAT signaling; Microbiology/Virology; NF-κB; Stem Cells
	Saikosaponin D 是一种从柴胡中分离到的三萜皂苷类天然产物，具有抗炎，抗菌，抗肿瘤，抗过敏作用。它抑制 selectin，STAT3和 NF-kB 的活性，活化estrogen receptor-β。
TN1079	Deoxyelephantopin	NF-κB	NF-κB
	Deoxyelephantopin 是来自Elephantopus scaber 的，具有生物活性的天然倍半萜烯内酯，能够抑制NF-κB，MAPK，PI3K/Akt 和β-catenin 信号传导。它可广泛用于癌症方面的研究。
T5S1607	Morusin Mulberrochromene,桑辛素	NF-κB; Antibacterial; STAT	JAK/STAT signaling; Microbiology/Virology; NF-κB; Stem Cells
	Morusin (Mulberrochromene) 是从M. australis 分离的去乙烯基化黄酮，可抑制NF-κB 和STAT3的活性，具有抗菌、抗肿瘤、抗氧化等各种生物活性。
T4S0217	HOMOPLANTAGININ	TNF; NF-κB	Apoptosis; NF-κB
	Homoplantaginin 是来自中药荔枝草的一种类黄酮，具有抗炎和抗氧化活性。
T4S1881	Aconine 乌头原碱,Jesaconine	Others; NF-κB	NF-κB; Others
	Aconine (Jesaconine) 是一种退热药，有胃麻醉作用，能够抑制核因子 κB 受体活化剂配体诱导的 NF-κB 激活。
T6S1572	Sauchinone	ERK; p38 MAPK; NF-κB	MAPK; NF-κB
	Sauchinone 是一种从Saururus chinensis 中获得的非对映异构的木脂素。它通过抑制I-κBα磷酸化和p65核易位来抑制 LPS 诱导的 iNOS，TNF-α 和 COX-2 表达。它具有抗炎和抗氧化活性。
TN1712	Gossypin	NF-κB; S6 Kinase	MAPK; NF-κB; PI3K/Akt/mTOR signaling
	Gossypin 是一种从Hibiscus vitifolius 中分离得到的黄酮，能够抑制NF-κB 和 NF-κB 的调节基因表达。在小鼠原代骨髓细胞和 RAW264.7 细胞中，它也可抑制 RANKL 诱导的破骨细胞形成。它具有抗氧化、抗炎、抗癌、抗衰老、抗糖尿病和保护肝脏的活性。
T5834	Myrcene	Others	Others
	Myrcene 是具有可挥发性的芳香族化合物，对 TNFα 诱导的 NF-κB 具有抑制作用，且具有抗侵袭的能力。
T2140	Parthenolide (-)-Parthenolide,小白菊内酯	Apoptosis; Mitophagy; NF-κB; HDAC; Autophagy	Apoptosis; Autophagy; Chromatin/Epigenetic; DNA Damage/DNA Repair; NF-κB
	Parthenolide ((-)-Parthenolide) 是一种从药草短舌匹菊中发现的倍半萜内酯。它抑制NF-κB 活化，有抗炎活性。它还可抑制HDAC1蛋白，但不影响其他I/II 类HDAC。
T6S0840	Engeletin Dihydrokaempferol 3-rhamnoside,黄杞苷	NF-κB; Reductase	Endocrinology/Hormones; Metabolism; NF-κB
	Engeletin (Dihydrokaempferol 3-rhamnoside) 是一种黄酮苷类物质，从hymenaea martiana 中获得，抑制NF-κB 信号通路的激活，具有抗炎、缓解疼痛、消肿、利尿、抗菌等作用。
T6718	Zingerone Gingerone,Vanillylacetone,姜酮,NSC 15335	NF-κB	NF-κB
	Zingerone (Vanillylacetone) 是一种从生姜中得到的无毒的甲氧基苯酚，具有抗炎、抗糖尿病、抗脂质过敏、抗腹泻、抗痉挛和抗肿瘤等活性。它作为抗有丝分裂剂，能够抑制神经母细胞瘤的生长。它能够缓解氧化应激和炎症，下调 NF-κB 介导的信号通路。
T5687	WITHAFERIN A 醉茄素 A,醉茄素A	Ferroptosis; NF-κB	Apoptosis; NF-κB
	Withaferin A 是从南非醉茄中分离到的一种甾体内酯，是内皮蛋白 C 受体脱落抑制剂，可以抑制NF-kB 的活性，具有抗炎，抗肿瘤等作用。它是一种新型 NFkappaB 抑制剂，有望成为治疗各种炎症性疾病和癌症的新型抗炎药。
TN1637	Eurycomalactone	Anti-infection; NF-κB	Microbiology/Virology; NF-κB
	Eurycomalactone 是一种NF-κB 抑制剂，IC50=0.5 μM，是一种天然产物。它可抑制蛋白合成，降低 cyclin D1 蛋白水平，但对 TNFα 诱导的 IκBα 降解或 IKKα/β 和 IκBα 的磷酸化水平没有作用。
T3012	Mangiferin Alpizarin,Chinomin,芒果,Hedysarid	Apoptosis; Others; NF-κB; Nrf2	Apoptosis; Immunology/Inflammation; NF-κB; Others
	Mangiferin (Hedysarid) 是一种Nrf2激活剂。它抑制NF-κB 亚基p65和p50的核移位，具有抗氧化、抗糖尿病、抗高尿酸血症、抗病毒、抗癌和抗炎活性。
TN1341	8-Deoxygartanin 8-脱氧藤黄苷	Beta Amyloid; NF-κB; Parasite	Microbiology/Virology; Neuroscience; NF-κB
	8-Deoxygartanin 是山竹果中的异戊烯化呫吨酮。它是丁基胆碱酯酶选择性抑制剂，对阿尔茨海默病 (AD) 具有多功能活性，可能是有希望治疗 AD 的化合物。
T6S0781	Phellodendrine 黄柏碱,Phallodendrin	Others; NF-κB; Akt	Cytoskeletal Signaling; NF-κB; Others; PI3K/Akt/mTOR signaling
	Phellodendrine (Phallodendrin) 是异喹啉生物碱，是黄柏皮层中的重要特征成分之一。它具有良好的抗氧化，抗炎作用。它通过调节AKT/NF-κB 途径抵抗 AAPH 诱导的氧化应激。
T2898	Andrographolide Andrographis,穿心莲内酯	SARS-CoV; Influenza Virus; NF-κB; Autophagy	Autophagy; Microbiology/Virology; NF-κB
	Andrographolide (Andrographis) 是 NF-κB 的不可逆拮抗剂，具有抗病毒、抗炎和抗血小板聚集活性和潜在的抗肿瘤作用。
T2733	Sarsasapogenin Parigenin,知母皂苷元,Sarsagenin	Apoptosis; NF-κB; Endogenous Metabolite	Apoptosis; Metabolism; NF-κB
	Sarsasapogenin (Parigenin) 是一种甾体皂苷元，从中草药知母中分离到，具有抗糖尿病、抗氧化、抗癌、抗炎等作用。
T2726	Sinomenine Cucoline,Kukoline,青藤碱	Apoptosis; Others; NF-κB; Opioid Receptor; Autophagy	Apoptosis; Autophagy; Endocrinology/Hormones; GPCR/G Protein; Neuroscience; NF-κB; Others
	Sinomenine (Kukoline) 是来自汉防己的一种生物碱，是 μ 阿片受体激活剂，也是NF-κB 活化的阻断剂。
T5S1891	Flaconitine 乙酰乌头碱,3-Acetylaconitine,Acetylaconitine	Others; NF-κB	NF-κB; Others
	Flaconitine (Acetylaconitine) 是一种 NF-κB 抑制剂，是一种生物碱。
T3777	Praeruptorin A (+)-Praeruptorin A,白花前胡甲素	CaMK; NF-κB	Neuroscience; NF-κB
	Praeruptorin A ((+)-Praeruptorin A) 是一种白花前胡的主要生物活性成分。它能够抑制 NF-κB 活化，发挥抗炎作用。
T2920	Berbamine dihydrochloride 盐酸小檗胺	Apoptosis; NF-κB; Bcr-Abl; Autophagy	Angiogenesis; Apoptosis; Autophagy; Cytoskeletal Signaling; NF-κB; Tyrosine Kinase/Adaptors
	Berbamine dihydrochloride (Berbamine) 是源自小檗植物的天然产物，是一种NF-κB 抑制剂，具有显著的抗骨髓瘤疗效。
T6S1966	Curculigoside Curculigoside A,仙茅苷	Antioxidant; NF-κB; JAK; STAT	Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; NF-κB; oxidation-reduction; Stem Cells
	Curculigoside (Curculigoside A) 是仙茅中的主要皂苷，具有显著的抗氧化、抗骨质疏松、抗抑郁和神经保护作用。它通过调节JAK/STAT/NF-κB 信号传导途径，具有抗关节炎作用。
T3907	Tenuigenin Senegenin,Senegin,远志皂苷元	NF-κB; Caspase; Antibacterial	Apoptosis; Microbiology/Virology; NF-κB; Proteases/Proteasome
	Tenuigenin (Senegenin) 是从中草药远志根中分离出来的主要活性成分，用于中药，具有抗氧化和抗炎活性。它抑制 NF-κB 活化，预防金黄色葡萄球菌诱导的肺炎。
T4S1615	Sanggenon C 桑根酮C,桑根酮 C,Sanggenone C	NF-κB	NF-κB
	Sanggenon C (Sanggenone C) 是一种从桑属的根皮中分离得到的黄烷酮 Diels-Alder 加合物化合物。它可抑制NF-κB 活性，抑制 RAW264.7 细胞中诱导型一氧化氮合酶的表达，以及肿瘤坏死因子-α 刺激的细胞粘附和血管细胞粘附分子-1 的表达。它具有抗氧化和抗炎作用，也有抑制胰脂肪酶作用。
TL0016	Sulforaphene 油菜	Apoptosis; ERK; EGFR; NF-κB	Angiogenesis; Apoptosis; JAK/STAT signaling; MAPK; NF-κB; Tyrosine Kinase/Adaptors
	Sulforaphene 是从萝卜种子中分离出来的天然产物，对鹿茸幼苗的 ED50 约为 2 x 10 -4 M。它通过抑制 EGFR、p-ERK1/2、NF-κB 和其他信号促进癌细胞凋亡并抑制迁移。
TN1410	Asperulosidic acid ASPA,车叶草苷酸	ERK; NF-κB	MAPK; NF-κB
	Asperulosidic acid (ASPA) 是从白花蛇舌草药中提取的一种环烯醚萜苷，具有抗肿瘤、抗氧化和抗炎作用。它通过抑制 NF-κB 和丝裂原活化蛋白激酶信号通路抑制炎性细胞因子释放发挥抗炎作用。
TN2244	Sulfuretin 硫黄菊素	NF-κB; Autophagy	Autophagy; NF-κB
	Sulfuretin 是竞争性单酚酶和二酚酶活性抑制剂，IC50=13.64 μM。它通过抑制NF-κB 通路来抑制炎症反应。它可用于过敏性气道炎症的研究。它减少氧化应激、血小板聚集和诱变。
TN2100	Pratensein 红车轴草素,三叶草	Others; NF-κB	NF-κB; Others
	Pratensein 是黄酮类化合物，能够减少氧化损伤和恢复突触和 BDNF 水平，改善 β-淀粉样蛋白诱导的大鼠认知障碍。
T3860	Isoliquiritin apioside	MMP; p38 MAPK; NF-κB	MAPK; NF-κB; Proteases/Proteasome
	Isoliquiritin apioside 可抑制癌细胞和内皮细胞的侵袭和血管生成，显著降低 PMA 诱导的MMP9活性增加，并抑制 PMA 诱导的MAPK 和NF-κB 活化。
T5S1097	Neferine (R)-1,2-Dimethoxyaporphine,(-)-Neferine,甲基莲心碱	Apoptosis; NF-κB; Autophagy	Apoptosis; Autophagy; NF-κB
	Neferine ((-)-Neferine) 是一种双苄基异喹啉类生物碱，可强效抑制NF-κB 激活，具有抗肿瘤活性。
T3027	Sodium Aescinate Escin sodium salt,七叶皂苷钠	HIF	Angiogenesis; Chromatin/Epigenetic
	Sodium Aescinate (Escin sodium salt) 是一种三萜皂苷，来源于Aesculus hippocastanum 的种子，具有抗炎、抗氧化作用。它可以通过靶向 CARMA3/NF-κB 途径，抑制抑制肝癌生长。
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天然产物

Cat.No: T5688

Target: NOS, NF-κB, COX

Cat.No: TN1131

Target: NF-κB, Immunology/Inflammation related

Cat.No: T13686

Target: NF-κB

Cat.No: T4S1540

Target: Apoptosis, NF-κB

Cat.No: T10383

Target: NF-κB

Cat.No: TMA0507

Target: NF-κB, JNK, Autophagy

Cat.No: T3S0807

Target: CaMK, NF-κB, Autophagy

Cat.No: T16324

Target: Apoptosis, NF-κB, CDK

Cat.No: T5795

Synonym: 软木花椒素

Target: Others, NF-κB

Cat.No: T3S1707

Synonym: Moscatilin

Target: NF-κB

Stachydrine Hydrochloride

Cat.No: T3251

Target: NF-κB

Esculentoside H

Cat.No: T3S1641

Target: TNF, NF-κB, JNK

Demethyleneberberine

Cat.No: T4S0800

Target: P450, NOS, NF-κB, HIF, AMPK

Cat.No: T6S0119

Synonym: 蝙蝠葛碱

Target: Apoptosis, Others, NF-κB

Cat.No: T5S2129

Target: TNF, NF-κB

Cat.No: T11060

Synonym: Dimethylamino Parthenolide

Target: NF-κB

Cat.No: TN2008

Target: NF-κB, TLR

Esculentoside A

Cat.No: T3877

Target: NF-κB, COX

Cat.No: T3913

Target: Estrogen Receptor/ERR, NF-κB, Antibacterial, STAT

Deoxyelephantopin

Cat.No: TN1079

Target: NF-κB

Cat.No: T5S1607

Synonym: Mulberrochromene,桑辛素

Target: NF-κB, Antibacterial, STAT

HOMOPLANTAGININ

Cat.No: T4S0217

Target: TNF, NF-κB

Cat.No: T4S1881

Synonym: 乌头原碱,Jesaconine

Target: Others, NF-κB

Cat.No: T6S1572

Target: ERK, p38 MAPK, NF-κB

Cat.No: TN1712

Target: NF-κB, S6 Kinase

Cat.No: T5834

Target: Others

Cat.No: T2140

Synonym: (-)-Parthenolide,小白菊内酯

Target: Apoptosis, Mitophagy, NF-κB, HDAC, Autophagy

Cat.No: T6S0840

Synonym: Dihydrokaempferol 3-rhamnoside,黄杞苷

Target: NF-κB, Reductase

Cat.No: T6718

Synonym: Gingerone,Vanillylacetone,姜酮,NSC 15335

Target: NF-κB

Cat.No: T5687

Synonym: 醉茄素 A,醉茄素A

Target: Ferroptosis, NF-κB

Eurycomalactone

Cat.No: TN1637

Target: Anti-infection, NF-κB

Cat.No: T3012

Synonym: Alpizarin,Chinomin,芒果,Hedysarid

Target: Apoptosis, Others, NF-κB, Nrf2

8-Deoxygartanin

Cat.No: TN1341

Synonym: 8-脱氧藤黄苷

Target: Beta Amyloid, NF-κB, Parasite

Cat.No: T6S0781

Synonym: 黄柏碱,Phallodendrin

Target: Others, NF-κB, Akt

Andrographolide

Cat.No: T2898

Synonym: Andrographis,穿心莲内酯

Target: SARS-CoV, Influenza Virus, NF-κB, Autophagy

Cat.No: T2733

Synonym: Parigenin,知母皂苷元,Sarsagenin

Target: Apoptosis, NF-κB, Endogenous Metabolite

Cat.No: T2726

Synonym: Cucoline,Kukoline,青藤碱

Target: Apoptosis, Others, NF-κB, Opioid Receptor, Autophagy

Cat.No: T5S1891

Synonym: 乙酰乌头碱,3-Acetylaconitine,Acetylaconitine

Target: Others, NF-κB

Cat.No: T3777

Synonym: (+)-Praeruptorin A,白花前胡甲素

Target: CaMK, NF-κB

Berbamine dihydrochloride

Cat.No: T2920

Synonym: 盐酸小檗胺

Target: Apoptosis, NF-κB, Bcr-Abl, Autophagy

Cat.No: T6S1966

Synonym: Curculigoside A,仙茅苷

Target: Antioxidant, NF-κB, JAK, STAT

Cat.No: T3907

Synonym: Senegenin,Senegin,远志皂苷元

Target: NF-κB, Caspase, Antibacterial

Cat.No: T4S1615

Synonym: 桑根酮C,桑根酮 C,Sanggenone C

Target: NF-κB

Cat.No: TL0016

Synonym: 油菜

Target: Apoptosis, ERK, EGFR, NF-κB

Asperulosidic acid

Cat.No: TN1410

Synonym: ASPA,车叶草苷酸

Target: ERK, NF-κB

Cat.No: TN2244

Synonym: 硫黄菊素

Target: NF-κB, Autophagy

Cat.No: TN2100

Synonym: 红车轴草素,三叶草

Target: Others, NF-κB

Isoliquiritin apioside

Cat.No: T3860

Target: MMP, p38 MAPK, NF-κB

Cat.No: T5S1097

Synonym: (R)-1,2-Dimethoxyaporphine,(-)-Neferine,甲基莲心碱

Target: Apoptosis, NF-κB, Autophagy

Sodium Aescinate

Cat.No: T3027

Synonym: Escin sodium salt,七叶皂苷钠

Target: HIF

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Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-02543	PCNA Protein, Human, Recombinant (His) ATLD2,proliferating cell nuclear antigen	Human	Baculovirus Insect Cells
	Proliferating Cell Nuclear Antigen (PCNA) is a protein only expressed in normal proliferate cells and cancer cells. It is central to both DNA replication and repair. One of the well-established functions for PCNA is its role as the processivity factor for DNA polymerase delta and epsilon. PCNA tethers the polymerase catalytic unit to the DNA template for rapid and processive DNA synthesis. Two forms of PCNA exist in cells: (i) a detergent-insoluble trimeric form stably associated with the replic...
TMPH-02359	Influenza B (strain B/Yamagata/1/1973) Nuclear export Protein (His) Non-structural protein 2,NS,Nuclear export protein	Influenza B	E. coli
	Influenza B (strain B/Yamagata/1/1973) Nuclear export Protein (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 18.4 kDa and the accession number is P08014.
TMPJ-00662	RANKL/TNFSF11/CD254 Protein, Human, Recombinant (E. coli) Receptor activator of nuclear factor kappa-B ligand...	Human	E. coli
	CD254, also known as RANKL, TNFSF11, TRANCE, OPGL and ODF, is a type II membrane protein of the tumor necrosis factor (TNF) superfamily, and affects the immune system and control bone regeneration and remodeling. RANKL is the ligand of nuclear factor (NF)-κB (RANK). When RANKL binds to RANK, it will undergo trimerization and then bind to an adaptor molecule TNF receptor-associated factor 6 (TRAF6). This results in the activation of several downstream signaling cascades, including the NFκB, mitog...
TMPJ-00607	RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (His) Receptor activator of nuclear factor κ-B ligand,Ost...	Mouse	HEK293 Cells
	RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with N-6xHis tag. The predicted molecular weight is 30-35 KDa and the accession number is BAA97257.1.
TMPH-00538	Epstein-Barr virus (strain GD1) EBNA3 Protein (His & Myc) Epstein-Barr nuclear antigen 3A,Epstein-Barr nu...	EBV	E. coli
	Plays an essential role for activation and immortalization of human B-cells. Represses transcription of viral promoters TP1 and Cp through interaction with host RBPJ, and inhibits EBNA2-mediated activation of these promoters. Since Cp is the promoter for all EBNA mRNAs, EBNA3A probably contributes to a negative autoregulatory control loop.
TMPH-01786	NCBP1 Protein, Human, Recombinant (His & Myc) Nuclear cap-binding protein subunit 1,NCBP1,80 kDa ...	Human	Baculovirus Insect Cells
	NCBP1 Protein, Human, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 95.7 kDa and the accession number is Q09161.
TMPY-04126	MUSTN1 Protein, Human, Recombinant (His) musculoskeletal, embryonic nuclear protein 1,MUSTAN...	Human	E. coli
	MUSTN1 (Musculoskeletal, Embryonic Nuclear Protein 1) is a Protein Coding gene. It may play an important role in regulating musculoskeletal development in mammals. It belongs to the MUSTANG family. The MUSTN1 protein is localized to the nucleus in the myocardium and skeletal muscle fibers. It was expressed the greatest in skeletal muscle. The greatest relative growth rates appeared at the highest expression levels of the MUSTN1 gene, it was thought to play roles in duck muscle development. MUSTN...
TMPH-01796	NR4A1 Protein, Human, Recombinant (His & Myc) ST-59,NR4A1,Nuclear hormone receptor NUR/77,Orphan ...	Human	E. coli
	Orphan nuclear receptor. May act concomitantly with NURR1 in regulating the expression of delayed-early genes during liver regeneration. Binds the NGFI-B response element (NBRE) 5'-AAAAGGTCA-3'. May inhibit NF-kappa-B transactivation of IL2. Participates in energy homeostasis by sequestrating the kinase STK11 in the nucleus, thereby attenuating cytoplasmic AMPK activation. Plays a role in the vascular response to injury. NR4A1 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expre...
TMPH-00537	Epstein-Barr virus (strain B95-8) EBNA3 Protein (His & Myc) Epstein-Barr nuclear antigen 3,EBNA3,Epstein-Barr <...	EBV	E. coli
	Plays an essential role for activation and immortalization of human B-cells. Represses transcription of viral promoters TP1 and Cp through interaction with host RBPJ, and inhibits EBNA2-mediated activation of these promoters. Since Cp is the promoter for all EBNA mRNAs, EBNA3A probably contributes to a negative autoregulatory control loop.
TMPH-01797	NR4A2 Protein, Human, Recombinant (His) NR4A2,Immediate-early response protein NOT,Nuclear ...	Human	P. pastoris (Yeast)
	Transcriptional regulator which is important for the differentiation and maintenance of meso-diencephalic dopaminergic (mdDA) neurons during development. It is crucial for expression of a set of genes such as SLC6A3, SLC18A2, TH and DRD2 which are essential for development of mdDA neurons. NR4A2 Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 68.6 kDa and the accession number is P43354.
TMPH-01464	HNRNPM Protein, Human, Recombinant (His & SUMO) Heterogeneous nuclear ribonucleoprotein M,HNRNPM	Human	E. coli
	Pre-mRNA binding protein in vivo, binds avidly to poly(G) and poly(U) RNA homopolymers in vitro. Involved in splicing. Acts as a receptor for carcinoembryonic antigen in Kupffer cells, may initiate a series of signaling events leading to tyrosine phosphorylation of proteins and induction of IL-1 alpha, IL-6, IL-10 and tumor necrosis factor alpha cytokines. HNRNPM Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weig...
TMPH-01793	NR1I2 Protein, Human, Recombinant (His & Myc & SUMO) Orphan nuclear receptor PXR,NR1I2,Steroid and xenob...	Human	E. coli
	NR1I2 Protein, Human, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Myc tag. The predicted molecular weight is 69.8 kDa and the accession number is O75469.
TMPH-01785	NCBP1 Protein, Human, Recombinant (E. coli, His & Myc) 80 kDa nuclear cap-binding protein,NCBP1,Nuclea...	Human	E. coli
	NCBP1 Protein, Human, Recombinant (E. coli, His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 99.3 kDa and the accession number is Q09161.
TMPH-02113	SSNA1 Protein, Human, Recombinant (His) Sjoegren syndrome nuclear autoantigen 1,Microtubule...	Human	E. coli
	N/A. SSNA1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 17.0 kDa and the accession number is O43805.
TMPH-01462	HNRNPH1 Protein, Human, Recombinant (GST) HNRNPH1,Heterogeneous nuclear ribonucleoprotein H	Human	E. coli
	This protein is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Mediates pre-mRNA alternative splicing regulation. Inhibits, together with CUGBP1, insulin receptor (IR) pre-mRNA exon 11 inclusion in myoblast. Binds to the IR RNA. Binds poly(RG). HNRNPH1 Protein, Human, Recombinant (GST) is expressed in E. coli expression system...
TMPH-01463	HNRNPL Protein, Human, Recombinant (His & SUMO) HNRNPL,Heterogeneous nuclear ribonucleoprotein L	Human	E. coli
	Splicing factor binding to exonic or intronic sites and acting as either an activator or repressor of exon inclusion. Exhibits a binding preference for CA-rich elements. Component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes and associated with most nascent transcripts. Associates, together with APEX1, to the negative calcium responsive element (nCaRE) B2 of the APEX2 promoter. HNRNPL Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6x...
TMPH-00506	NXF2 Protein, Drosophila melanogaster, Recombinant (His) nxf2,Nuclear RNA export factor 2	Fruit fly	Baculovirus Insect Cells
	NXF2 Protein, Drosophila melanogaster, Recombinant (His) is expressed in Baculovirus insect cells with C-6xHis tag. The predicted molecular weight is 33.7 kDa and the accession number is Q9VV73.
TMPH-01461	HNRNPA3 Protein, Human, Recombinant (His & Myc) Heterogeneous nuclear ribonucleoprotein A3,HNRNPA3	Human	E. coli
	Plays a role in cytoplasmic trafficking of RNA. Binds to the cis-acting response element, A2RE. May be involved in pre-mRNA splicing. HNRNPA3 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 46.6 kDa and the accession number is P51991.
TMPY-04268	NUDC Protein, Human, Recombinant (His) nudC nuclear distribution protein,MNUDC,HNUDC,NPD01...	Human	HEK293 Cells
	NUDC (Nuclear Distribution C, Dynein Complex Regulator) is a Protein Coding gene. NUDC consists of at least 9 exons ranging from 66 bp to 266 bp in size and 8 introns from 92 bp to 2.0 kb in length, and the total genomic region spans about 8 kb. NUDC was mapped to 1p34-p35 by fluorescence in situ hybridization. This gene encodes a nuclear distribution protein that plays an essential role in mitosis and cytokinesis. Nuclear migration is essential for the growth, development, and cellular function...
TMPH-02705	HNRNPA2B1 Protein, Mouse, Recombinant (His & Myc & SUMO) Hnrnpa2b1,Heterogeneous nuclear ribonucleoproteins ...	Mouse	E. coli
	HNRNPA2B1 Protein, Mouse, Recombinant (His & Myc & SUMO) is expressed in E. coli.
TMPH-00536	Epstein-Barr virus (strain AG876) EBNA2 Protein (His & Myc) Epstein-Barr nuclear antigen 2,EBNA2	EBV	P. pastoris (Yeast)
	Plays a key role in the activation of the host resting B-cell and stimulation of B-cell proliferation. Acts by up-regulating the expression of viral EBNA1-6, LMP1, LMP2A and LMP2B genes, as well as several host genes including CD21, CD23 and MYC. Activates transcription by acting as an adapter molecule that binds to cellular sequence-specific DNA-binding proteins such as host CBF1, SMARCB1 and SPI1. Once EBNA2 is near promoter sites, its acidic activating domain recruits basal and activation-ass...
TMPH-01788	NFE2L2 Protein, Human, Recombinant (His) HEBP1,Nuclear factor erythroid 2-related factor 2,N...	Human	E. coli
	NFE2L2 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 42.9 kDa and the accession number is Q16236.
TMPH-01465	HNRNPA2B1 Protein, Human, Recombinant (His & Myc) HNRNPA2B1,Heterogeneous nuclear ribonucleoproteins ...	Human	E. coli
	HNRNPA2B1 Protein, Human, Recombinant (His & Myc) is expressed in E. coli.
TMPY-03286	hnRNP-R Protein, Human, Recombinant (His & GST) hnRNP-R,HNRPR,heterogeneous nuclear ribonucleoprote...	Human	Baculovirus Insect Cells
	HNRNP R, also known as HNRNPR, is an RNA binding protein. HNRNP R gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). HnRNPs complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The ...
TMPH-01791	RORA Protein, Human, Recombinant (His) Retinoid-related orphan receptor-alpha,Nuclear rece...	Human	E. coli
	RORA Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 57.6 kDa and the accession number is P35398.
TMPH-00271	HNRNPA2B1 Protein, Bovine, Recombinant (His & SUMO) Heterogeneous nuclear ribonucleoproteins A2/B1,HNRN...	Bovine	E. coli
	HNRNPA2B1 Protein, Bovine, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 52.0 kDa and the accession number is Q2HJ60.
TMPJ-00904	NFYA Protein, Human, Recombinant (GST) Nuclear Transcription Factor Y Subunit Alpha,Nu...	Human	E. coli
	NFYA Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 55 KDa and the accession number is P23511-2.
TMPH-01792	RORC Protein, Human, Recombinant (His & SUMO) Nuclear receptor subfamily 1 group F member 3,RAR-r...	Human	E. coli
	RORC Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 74.2 kDa and the accession number is P51449.
TMPJ-00903	NFYA Protein, Human, Recombinant CAAT Box DNA-Binding Protein Subunit A,Nuclear Tran...	Human	E. coli
	NFYA Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 40 and 60 and 70 KDa and the accession number is P23511-2.
TMPH-01789	NUP98 Protein, Human, Recombinant (hFc) Nuclear pore complex protein Nup98-Nup96,NUP98	Human	HEK293 Cells
	NUP98 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 120.6 kDa and the accession number is P52948.
TMPH-02280	SNRNP70 Protein, Human, Recombinant (His) U1 small nuclear ribonucleoprotein 70 kDa,SNRNP70	Human	E. coli
	Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRNP70 binds to the loop I region of U1-snRNA.; Truncated isoforms that lack the RRM domain cannot bind U1-snRNA.; Truncated isoforms that lack the RRM domain cannot bind U1-snRNA. SNRNP70 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 28.7 kDa and the accession n...
TMPH-01790	NUP210 Protein, Human, Recombinant (His) NUP210,Nucleoporin Nup210,Nuclear pore membrane gly...	Human	E. coli
	Nucleoporin essential for nuclear pore assembly and fusion, nuclear pore spacing, as well as structural integrity. NUP210 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 34.5 kDa and the accession number is Q8TEM1.
TMPH-01437	HNF4A Protein, Human, Recombinant (His & Myc) Transcription factor HNF-4,HNF4A,Nuclear receptor s...	Human	E. coli
	HNF4A Protein, Human, Recombinant (His & Myc) is expressed in E. coli.
TMPY-02883	C1D Protein, Human, Recombinant (GST) SUNCOR,Rrp47,SUN-CoR,hC1D,C1D nuclear receptor core...	Human	E. coli
	C1D nuclear receptor corepressor belongs to the C1D family. It is a DNA binding and apoptosis-inducing protein.C1D nuclear receptor corepressorinteracts with TSNAX and DNA-PKcs. It acts as a corepressor for the thyroid hormone receptor. It is thought that C1D nuclear receptor corepressor regulates TRAX/Translin complex formation. It is expressed in kidney, heart, brain, spleen, lung, testis, liver and small intestine. It plays a role in the recruitment of the RNA exosome complex to pre-rRNA to m...
TMPH-00535	Epstein-Barr virus (strain B95-8) BHRF1 Protein (His) Nuclear antigen,Apoptosis regulator BHRF1,Early ant...	EBV	E. coli
	Prevents premature death of the host cell during virus production, which would otherwise reduce the amount of progeny virus. Acts as a host B-cell leukemia/lymphoma 2 (Bcl-2) homolog, and interacts with pro-apoptotic proteins to prevent mitochondria permeabilization, release of cytochrome c and subsequent apoptosis of the host cell.
TMPH-01419	RAN Protein, Human, Recombinant (GST) Ras-like protein TC4,GTPase Ran,RAN,GTP-binding nuclear<...	Human	E. coli
	RAN Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 51.3 kDa and the accession number is P62826.
TMPY-00473	NRBF2 Protein, Human, Recombinant (His & GST) NRBF-2,nuclear receptor binding factor 2,COPR2,COPR...	Human	Baculovirus Insect Cells
	NRBF2 (Nuclear Receptor Binding Factor 2) is a Protein Coding gene. The encoded protein may modulate transcriptional activation by target nuclear receptors. It is widely expressed in the appendix, placenta, and other tissues. NRBF2/Atg38 has been identified as the fifth subunit of the macroautophagy/autophagy class III phosphatidylinositol 3-kinase (PtdIns3K) complex, along with ATG14/Barkor, BECN1/Vps30, PIK3R4/p150/Vps15, and PIK3C3/Vps34. NRBF2 is a critical molecular switch of PtdIns3K and a...
TMPH-03755	Ppard Protein, Human, Recombinant (His) NUCI,Peroxisome proliferator-activated receptor delta,PPARD,...	Human	E. coli
	Ligand-activated transcription factor. Receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Has a preference for poly-unsaturated fatty acids, such as gamma-linoleic acid and eicosapentanoic acid. Once activated by a ligand, the receptor binds to promoter elements of target genes. Regulates the peroxisomal beta-oxidation pathway of fatty acids. Functions as transcription activator for the acyl-CoA oxidase gene. Decreases expression of NPC1L1 once activated by...
TMPH-01787	NCBP2 Protein, Human, Recombinant (GST) NCBP2,Nuclear cap-binding protein subunit 2,NCBP 20...	Human	E. coli
	NCBP2 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 44.9 kDa and the accession number is P52298.
TMPH-01532	IKBKB Protein, Human, Recombinant (E. coli, His) Nuclear factor NF-kappa-B inhibitor kinase beta,Ser...	Human	E. coli
	Serine kinase that plays an essential role in the NF-kappa-B signaling pathway which is activated by multiple stimuli such as inflammatory cytokines, bacterial or viral products, DNA damages or other cellular stresses. Acts as part of the canonical IKK complex in the conventional pathway of NF-kappa-B activation. Phosphorylates inhibitors of NF-kappa-B on 2 critical serine residues. These modifications allow polyubiquitination of the inhibitors and subsequent degradation by the proteasome. In tu...
TMPY-03344	LSM3 Protein, Human, Recombinant (His) SMX4,YLR438C,USS2,LSM3 homolog, U6 small nuclear RN...	Human	E. coli
	LSM3 (LSM3 Homolog, U6 Small Nuclear RNA And MRNA Degradation Associated) is a Protein Coding gene. LSM3 is a member of the snRNP Sm proteins family. It plays role in pre-mRNA splicing as a component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as a component of the pre-catalytic spliceosome (spliceosome B complex). Sm-like proteins can be detected in a variety of organisms. They all have the Sm sequence motif, which consists of 2 regions separated by a linker ...
TMPH-01531	IKBKB Protein, Human, Recombinant (His) Serine/threonine protein kinase IKBKB,Nuclear facto...	Human	Baculovirus Insect Cells
	Serine kinase that plays an essential role in the NF-kappa-B signaling pathway which is activated by multiple stimuli such as inflammatory cytokines, bacterial or viral products, DNA damages or other cellular stresses. Acts as part of the canonical IKK complex in the conventional pathway of NF-kappa-B activation. Phosphorylates inhibitors of NF-kappa-B on 2 critical serine residues. These modifications allow polyubiquitination of the inhibitors and subsequent degradation by the proteasome. In tu...
TMPH-01304	ER beta Protein, Human, Recombinant (E. coli, His) ESR2,Nuclear receptor subfamily 3 group A member 2,...	Human	E. coli
	Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1/ER-alpha, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner.; Lacks ligand binding ability and has no or only very low ERE binding activity resulting in the loss of ligand-dependent transactivation ability. ER beta Protein, Human, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight...
TMPH-01884	PCBP2 Protein, Human, Recombinant (His & Myc) Heterogeneous nuclear ribonucleoprotein E2,PCBP2,Al...	Human	E. coli
	PCBP2 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 46.0 kDa and the accession number is Q15366.
TMPH-01305	ER beta Protein, Human, Recombinant (His) Nuclear receptor subfamily 3 group A member 2,Estro...	Human	P. pastoris (Yeast)
	Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1/ER-alpha, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner.; Lacks ligand binding ability and has no or only very low ERE binding activity resulting in the loss of ligand-dependent transactivation ability. ER beta Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 61.1 kDa and the accessio...
TMPY-06756	NR1H4 Protein, Mouse, Recombinant (His) nuclear receptor subfamily 1, group H, member 4,AI9...	Mouse	E. coli
	NR1H4 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 27.80 kDa.
TMPH-00932	Androgen receptor Protein, Human, Recombinant (His & Myc & SUMO) Nuclear receptor subfamily 3 group C member 4,AR,NR...	Human	E. coli
	Androgen receptor Protein, Human, Recombinant (His & Myc & SUMO) is expressed in E. coli.
TMPH-01436	FOXA1 Protein, Human, Recombinant (His & Myc) Transcription factor 3A,Forkhead box protein A1,FOXA1,Hepato...	Human	E. coli
	FOXA1 Protein, Human, Recombinant (His & Myc) is expressed in E. coli.
TMPH-02052	RBMX Protein, Human, Recombinant (GST) Glycoprotein p43,RNA-binding motif protein, X chromosome,RBM...	Human	E. coli
	RBMX Protein, Human, Recombinant (GST) is expressed in E. coli.
TMPY-06836	NR3C1 Protein, Human, Recombinant (His) GCCR,GRL,GR,nuclear receptor subfamily 3, group C, ...	Human	E. coli
	NR3C1 (Nuclear Receptor Subfamily 3 Group C Member 1) is a Protein Coding gene. This gene encodes glucocorticoid receptor, which can function both as a transcription factor that binds to glucocorticoid response elements in the promoters of glucocorticoid responsive genes to activate their transcription, and as a regulator of other transcription factors. NR3C1 is a transcriptional regulator of many drug-metabolizing enzymes and anti-inflammatory molecules. NR3C1 polymorphisms associate with obesi...
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重组蛋白

PCNA Protein, Human, Recombinant (His)

Cat.No: TMPY-02543

Species: Human

Expression System: Baculovirus Insect Cells

Influenza B (strain B/Yamagata/1/1973) Nuclear export Protein (His)

Cat.No: TMPH-02359

Species: Influenza B

Expression System: E. coli

RANKL/TNFSF11/CD254 Protein, Human, Recombinant (E. coli)

Cat.No: TMPJ-00662

Species: Human

Expression System: E. coli

RANKL/TNFSF11/CD254 Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-00607

Species: Mouse

Expression System: HEK293 Cells

Epstein-Barr virus (strain GD1) EBNA3 Protein (His & Myc)

Cat.No: TMPH-00538

Species: EBV

Expression System: E. coli

NCBP1 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-01786

Species: Human

Expression System: Baculovirus Insect Cells

MUSTN1 Protein, Human, Recombinant (His)

Cat.No: TMPY-04126

Species: Human

Expression System: E. coli

NR4A1 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-01796

Species: Human

Expression System: E. coli

Epstein-Barr virus (strain B95-8) EBNA3 Protein (His & Myc)

Cat.No: TMPH-00537

Species: EBV

Expression System: E. coli

NR4A2 Protein, Human, Recombinant (His)

Cat.No: TMPH-01797

Species: Human

Expression System: P. pastoris (Yeast)

HNRNPM Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-01464

Species: Human

Expression System: E. coli

NR1I2 Protein, Human, Recombinant (His & Myc & SUMO)

Cat.No: TMPH-01793

Species: Human

Expression System: E. coli

NCBP1 Protein, Human, Recombinant (E. coli, His & Myc)

Cat.No: TMPH-01785

Species: Human

Expression System: E. coli

SSNA1 Protein, Human, Recombinant (His)

Cat.No: TMPH-02113

Species: Human

Expression System: E. coli

HNRNPH1 Protein, Human, Recombinant (GST)

Cat.No: TMPH-01462

Species: Human

Expression System: E. coli

HNRNPL Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-01463

Species: Human

Expression System: E. coli

NXF2 Protein, Drosophila melanogaster, Recombinant (His)

Cat.No: TMPH-00506

Species: Fruit fly

Expression System: Baculovirus Insect Cells

HNRNPA3 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-01461

Species: Human

Expression System: E. coli

NUDC Protein, Human, Recombinant (His)

Cat.No: TMPY-04268

Species: Human

Expression System: HEK293 Cells

HNRNPA2B1 Protein, Mouse, Recombinant (His & Myc & SUMO)

Cat.No: TMPH-02705

Species: Mouse

Expression System: E. coli

Epstein-Barr virus (strain AG876) EBNA2 Protein (His & Myc)

Cat.No: TMPH-00536

Species: EBV

Expression System: P. pastoris (Yeast)

NFE2L2 Protein, Human, Recombinant (His)

Cat.No: TMPH-01788

Species: Human

Expression System: E. coli

HNRNPA2B1 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-01465

Species: Human

Expression System: E. coli

hnRNP-R Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-03286

Species: Human

Expression System: Baculovirus Insect Cells

RORA Protein, Human, Recombinant (His)

Cat.No: TMPH-01791

Species: Human

Expression System: E. coli

HNRNPA2B1 Protein, Bovine, Recombinant (His & SUMO)

Cat.No: TMPH-00271

Species: Bovine

Expression System: E. coli

NFYA Protein, Human, Recombinant (GST)

Cat.No: TMPJ-00904

Species: Human

Expression System: E. coli

RORC Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-01792

Species: Human

Expression System: E. coli

NFYA Protein, Human, Recombinant

Cat.No: TMPJ-00903

Species: Human

Expression System: E. coli

NUP98 Protein, Human, Recombinant (hFc)

Cat.No: TMPH-01789

Species: Human

Expression System: HEK293 Cells

SNRNP70 Protein, Human, Recombinant (His)

Cat.No: TMPH-02280

Species: Human

Expression System: E. coli

NUP210 Protein, Human, Recombinant (His)

Cat.No: TMPH-01790

Species: Human

Expression System: E. coli

HNF4A Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-01437

Species: Human

Expression System: E. coli

C1D Protein, Human, Recombinant (GST)

Cat.No: TMPY-02883

Species: Human

Expression System: E. coli

Epstein-Barr virus (strain B95-8) BHRF1 Protein (His)

Cat.No: TMPH-00535

Species: EBV

Expression System: E. coli

RAN Protein, Human, Recombinant (GST)

Cat.No: TMPH-01419

Species: Human

Expression System: E. coli

NRBF2 Protein, Human, Recombinant (His & GST)

Cat.No: TMPY-00473

Species: Human

Expression System: Baculovirus Insect Cells

Ppard Protein, Human, Recombinant (His)

Cat.No: TMPH-03755

Species: Human

Expression System: E. coli

NCBP2 Protein, Human, Recombinant (GST)

Cat.No: TMPH-01787

Species: Human

Expression System: E. coli

IKBKB Protein, Human, Recombinant (E. coli, His)

Cat.No: TMPH-01532

Species: Human

Expression System: E. coli

LSM3 Protein, Human, Recombinant (His)

Cat.No: TMPY-03344

Species: Human

Expression System: E. coli

IKBKB Protein, Human, Recombinant (His)

Cat.No: TMPH-01531

Species: Human

Expression System: Baculovirus Insect Cells

ER beta Protein, Human, Recombinant (E. coli, His)

Cat.No: TMPH-01304

Species: Human

Expression System: E. coli

PCBP2 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-01884

Species: Human

Expression System: E. coli

ER beta Protein, Human, Recombinant (His)

Cat.No: TMPH-01305

Species: Human

Expression System: P. pastoris (Yeast)

NR1H4 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-06756

Species: Mouse

Expression System: E. coli

Androgen receptor Protein, Human, Recombinant (His & Myc & SUMO)

Cat.No: TMPH-00932

Species: Human

Expression System: E. coli

FOXA1 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-01436

Species: Human

Expression System: E. coli

RBMX Protein, Human, Recombinant (GST)

Cat.No: TMPH-02052

Species: Human

Expression System: E. coli

NR3C1 Protein, Human, Recombinant (His)

Cat.No: TMPY-06836

Species: Human

Expression System: E. coli

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Cat. No.	Product Name	Target	Signaling Pathways
T9242	Dimethyl-d6 Sulfoxide	Others	Others
	Dimethyl-d6 Sulfoxide 是二甲基亚砜 (DMSO, (CH3) 2S = O) 的氢 (“H”) 被另一种同位素氘 (“d”) 取代的形式。二甲基-d6 亚砜是核磁共振光谱中的常用溶剂。
TMIJ-0208	Beclomethasone Dipropionate-d6
	Beclomethasone Dipropionate-d6 是 Beclomethasone Dipropionate 的氘代化合物。Beclomethasone Dipropionate 的 CAS 号为 5534-09-8。Betamethasone dipropionate是具有口服活性的糖皮质激素，具有抗炎和免疫抑制作用。它是Betamethasone 的前体药物，Betamethasone 是 LPS 诱导的炎症及 MMP 释放的抑制剂。
TMIJ-0402	N-Nitrosodiethylamine-d10
	N-Nitrosodiethylamine-d10 是 N-Nitrosodiethylamine 的氘代化合物。N-Nitrosodiethylamine 的 CAS 号为 55-18-5。N-Nitrosodiethylamine 是致癌物质二烷基硝胺。它主要存在于水、烟草烟雾、腌制食品、油炸食品以及许多酒精饮料中。它与DNA修复/复制相关的核酶的变化相关。
TMIH-0091	AOH-d3
	AOH-d3 是 AOH 的氘代化合物。AOH 的 CAS 号为 2089314-64-5。AOH1996 是一种具有口服活性的复制体组分 PCNA (增殖细胞核抗原) 配体，靶向转录-复制冲突 (TRC)。AOH1996 可干扰 PCNA 与其结合蛋白的相互作用，导致 DNA 复制应激，诱导细胞凋亡 (apoptosis)。AOH1996 通过稳定 PCNA 和 RNA 聚合酶 II 的相互作用从而导致蛋白酶体依赖的 rpb1 降解和致命的 DNA 损伤。AOH1996 与 DNA 损伤剂具有协同作用，可抑制肿瘤细胞生长。
TMIH-0025	13C-d3-AOH1996
	13C-d3-AOH1996 是 AOH1996 的 13C 和氘代化合物。AOH1996 的 CAS 号为 2089314-64-5。AOH1996 是一种具有口服活性的复制体组分 PCNA (增殖细胞核抗原) 配体，靶向转录-复制冲突 (TRC)。AOH1996 可干扰 PCNA 与其结合蛋白的相互作用，导致 DNA 复制应激，诱导细胞凋亡 (apoptosis)。AOH1996 通过稳定 PCNA 和 RNA 聚合酶 II 的相互作用从而导致蛋白酶体依赖的 rpb1 降解和致命的 DNA 损伤。AOH1996 与 DNA 损伤剂具有协同作用，可抑制肿瘤细胞生长。

同位素标记化合物

Dimethyl-d6 Sulfoxide

Cat.No: T9242

Target: Others

Beclomethasone Dipropionate-d6

Cat.No: TMIJ-0208

N-Nitrosodiethylamine-d10

Cat.No: TMIJ-0402

Cat.No: TMIH-0091

Cat.No: TMIH-0025

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