|
TMPY-04460
|
OXSR1 Protein, Human, Recombinant (GST)
OSR1,oxidative stress responsive 1
|
Human
|
Baculovirus Insect Cells
|
|
Oxidative stress-responsive 1 protein (OXSR1), also known as Serine/threonine-protein kinase OSR1, is a member of the Ser/Thr protein kinase family of proteins. OXSR1 regulates downstream kinases in response to environmental stress, and may play a role in regulating the actin cytoskeleton. OXSR1 is a 58 kDa protein of 527 amino acids that is widely expressed in mammalian tissues and cell lines. The amino acid (aa) sequence of the predicted OXSR1 protein is 39% identical to that of human SOK1. Of... |
|
TMPH-00753
|
UspD Protein, E. coli, Recombinant (His)
uspD,Universal stress protein D
|
E. coli
|
E. coli
|
|
Required for resistance to DNA-damaging agents. |
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TMPH-03473
|
UspA Protein, Salmonella typhi, Recombinant (His)
Universal stress protein A,uspA
|
Salmonella typhi
|
E. coli
|
|
Required for resistance to DNA-damaging agents. UspA Protein, Salmonella typhi, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 19.9 kDa and the accession number is Q8Z268. |
|
TMPJ-00433
|
VSIR Protein, Cynomolgus, Recombinant (His)
Stress-induced secreted protein-1,Platelet receptor...
|
Cynomolgus
|
HEK293 Cells
|
|
platelet receptor Gi24 is a single-pass type I membrane protein, and located at the cell surface. The protein can be cleaved by MMP14, and stimulate MMP14-mediated MMP2 activation. It is participated in the BMP signaling pathway. It also regulates the CD4-pasitive, alpha-beta T cell proliferation, and T cell cytokine production negatively. However, the protein can regulate stem cell differentiation positively. |
|
TMPH-00774
|
SAM22 Protein, Glycine max, Recombinant (His)
Pathogenesis-related protein 10,PR-10,Stress-induce...
|
Glycine max
|
P. pastoris (Yeast)
|
|
Involved in disease resistance. SAM22 Protein, Glycine max, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 18.8 kDa and the accession number is P26987. |
|
TMPH-01250
|
MAP2K3 Protein, Human, Recombinant (His & SUMO)
MAP2K3,MAPK/ERK kinase 3,Dual specificity mitogen-activated ...
|
Human
|
E. coli
|
|
Dual specificity kinase. Is activated by cytokines and environmental stress in vivo. Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in the MAP kinase p38. Part of a signaling cascade that begins with the activation of the adrenergic receptor ADRA1B and leads to the activation of MAPK14. MAP2K3 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 55.3 kDa and the accession numbe... |
|
TMPH-03072
|
MPK5 Protein, Japonica rice, Recombinant (His & Myc)
MPK5,Multiple stress-responsive MAP kinase 2,MAP ki...
|
Rice
|
E. coli
|
|
MPK5 Protein, Japonica rice, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 48.0 kDa and the accession number is Q10N20. |
|
TMPJ-01372
|
Cornulin Protein, Human, Recombinant (His)
Tumor-Related Protein,58 kDa Heat Shock Protein,PDRC1,C1orf1...
|
Human
|
E. coli
|
|
Cornulin is a member of the fused gene family of molecular chaperones. Human Cornulin contains N-terminus EF-hand domains and Ca2+ binding domains, and two glutamine- and threonine-rich 60 amino acid repeats in its C-terminus. Cornulin involves in the mucosal/epithelial immune response and epidermal differentiation. Cornulin is a survival factor that participates in the clonogenicity of squamous esophageal epithelium cell lines, attenuates deoxycholic acid (DCA)-induced apoptotic cell death and ... |
|
TMPJ-01382
|
HSPB8 Protein, Human, Recombinant (His)
Small stress protein-like protein HSP22,CRYAC,E2IG1...
|
Human
|
E. coli
|
|
Heat shock protein beta-8 (HSPB8) belongs to the small heat shock protein (HSP20) family. This protein can be inducted by 17-beta-estradiol, and is predominantly expressed in skeletal muscle and heat, mainly located in the cytoplasm and nucleus. HSPB8 usually exists in monomer, it can interact with HSPB1 and DNAJB6. HSPB8 displays temperature-dependent chaperone activity，appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have bee... |
|
TMPY-04329
|
Vimentin Protein, Human, Recombinant (His)
CTRCT30,HEL113,vimentin
|
Human
|
Baculovirus Insect Cells
|
|
Vimentin is a type III intermediate filament (IF) protein found in various non-epithelial cells, especially mesenchymal cells. A vimentin monomer, has a central α-helical domain and carboxyl (tail) domains. Two monomers compose the basic subunit of vimentin assembly. Vimentin is crucial for supporting and anchoring the position of the organelles in the cytosol. Vimentin provided cells with a resilience absent from the microtubule or actin filament networks, when under mechanical stress in vivo. ... |
|
TMPY-00541
|
LON PROTEASE Protein, E. coli, Recombinant (His)
|
E. coli
|
E. coli
|
|
Lon protease, an ATP-dependent mitochondrial protease, is important in mitochondrial protein maintenance. Lon protease is a multifunctional enzyme, and its functions include the degradation of damaged proteins and naturally short-lived proteins, ATPase and chaperone-like activities, as well as DNA binding. Lon protease plays a major role in the protein quality control system in mammalian cell mitochondria. It is present in the mitochondrial matrix and degrades oxidized and misfolded proteins, th... |
|
TMPY-04572
|
MKK4 Protein, Mouse, Recombinant (His & GST)
MKK4,MEK4,PRKMK4,Sek1,JNKK1,Serk1,mitogen-activated protein ...
|
Mouse
|
Baculovirus Insect Cells
|
|
Dual specificity mitogen-activated protein kinase kinase 4, also known as MAP kinase kinase 4, MAPKK4, JNK-activating kinase 1, MAPK/ERK kinase 4, SAPK/ERK kinase 1, c-Jun N-terminal kinase kinase 1, JNKK, and MAP2K4, is a protein that belongs to the protein kinase superfamily, STE Ser/Thr protein kinase family and MAP kinase kinase subfamily. MAP2K4 / JNKK1 is a protein kinase that is a direct activator of MAP kinases in response to various environmental stresses or mitogenic stimuli. MAP2K4 / ... |
|
TMPY-03962
|
AFM Protein, Human, Recombinant (His)
afamin,ALBA,ALB2,ALF
|
Human
|
HEK293 Cells
|
|
Afamin is an 87 kDa glycoprotein with five predicted N-glycosylation sites. Afamin's glycan abundance contributes to conformational and chemical inhomogeneity presenting great challenges for molecular structure determination. Afamin, a human plasma glycoprotein and putative transporter of hydrophobic molecules, has been shown to act as extracellular chaperone for poorly soluble, acylated Wnt proteins, forming a stable, soluble complex with functioning Wnt proteins. The 2.1-Å crystal structure of... |
|
TMPY-02078
|
HtrA2/Omi Protein, Human, Recombinant (His)
PARK13,OMI,HtrA serine peptidase 2,PRSS25
|
Human
|
E. coli
|
|
Serine protease HTRA2, also known as high-temperature requirement protein A2, Omi stress-regulated endoprotease, Serine protease 25, Serine proteinase OMI and HTRA2, is a single-pass membrane protein that belongs to the peptidase S1B family. HTRA2 contains one PDZ (DHR) domain. HTRA2 is a serine protease that shows proteolytic activity against a non-specific substrate beta-casein. It promotes or induces cell death either by direct binding to and inhibition of BIRC proteins (also called inhibitor... |
|
TMPY-04396
|
C-ABL/ABL1 Protein, Human, Recombinant (GST)
v-abl,ABL,JTK7,ABL proto-oncogene 1, non-receptor tyrosine k...
|
Human
|
Baculovirus Insect Cells
|
|
c-Abl belongs to the class of tyrosine kinases and is the prototype of a subfamily which includes two members, c-Abl and Arg (Abl-related gene). Both proteins are localized at the cell membrane, actin cytoskeleton and cytosol, and c-Abl is present in the nucleus as well. c-Abl is a non-receptor tyrosine kinase that participates in multiple signaling pathways linking the cell surface, cytoskeleton, and the nucleus. Recent in vitro studies have also linked c-Abl to amyloid-beta-induced toxicity an... |
|
TMPH-02587
|
CIRBP Protein, Mouse, Recombinant (His)
CIRP,A18 hnRNP,Glycine-rich RNA-binding protein CIRP,CIRBP,C...
|
Mouse
|
E. coli
|
|
Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. Promotes assembly of stress granules (SGs), when overexpressed. Seems to play an essential role in cold-induced suppression of cell proliferation. Acts as a translational repressor. Acts as a translational activator. Binds specifically to the 3'-untranslated regions (3'-UTRs) of stress-responsive transcripts RPA2 and TXN. |
|
TMPY-02648
|
PACAP receptor/ADCYAP1R1 Protein, Human, Recombinant (hFc)
adenylate cyclase activating polypeptide 1 (pituitary) recep...
|
Human
|
HEK293 Cells
|
|
Pituitary adenylate cyclase activating polypeptide (PACAP, Adcyap1) activation of PAC1 receptors ( Adcyap1r1) significantly increases excitability of guinea pig cardiac neurons. This modulation of excitability is mediated in part by plasma membrane G protein-dependent activation of adenylyl cyclase and downstream signaling cascades. Studies point to the potential role of the (pituitary) adenylate cyclase activating polypeptide receptor 1 (ADCYAP1R1) gene, which has been implicated in stress resp... |
|
TMPY-02072
|
HSF1 Protein, Human, Recombinant (His)
HSTF1,heat shock transcription factor 1
|
Human
|
E. coli
|
|
Heat shock factor protein 1, also known as heat shock transcription factor 1, HSF1, and HSTF1, is a cytoplasm and nucleus protein that belongs to the HSF family. HSF1 is the major transcription factor of HSPs (heat shock proteins) in response to various stresses. Wild type HSF1 (heat shock transcriptional factor 1) is normally inactive. HSF1 / HSTF1 is a DNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription. In higher eukaryotes, HSF is unable... |
|
TMPH-00731
|
RpoS Protein, E. coli, Recombinant
RNA polymerase sigma factor RpoS,rpoS,Sigma S,Sigma-38
|
E. coli
|
E. coli
|
|
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response. Controls, positively or negatively, the expression of several hundred genes, which are mainly involved in metabolism, transport, regulation and stress management.; Protects stationary phase cells from killing induced by endoribonuclease MazF. |
|
TMPH-01664
|
OMA1 Protein, Human, Recombinant (His & SUMO)
Overlapping with the m-AAA protease 1 homolog,OMA1,Metallopr...
|
Human
|
E. coli
|
|
Metalloprotease that is part of the quality control system in the inner membrane of mitochondria. Activated in response to various mitochondrial stress, leading to the proteolytic cleavage of target proteins, such as OPA1, UQCC3 and DELE1. Following stress conditions that induce loss of mitochondrial membrane potential, mediates cleavage of OPA1 at S1 position, leading to OPA1 inactivation and negative regulation of mitochondrial fusion. Also acts as a regulator of apoptosis: upon BAK and BAX ag... |
|
TMPH-00730
|
RpoS Protein, E. coli, Recombinant (His)
Sigma S,rpoS,RNA polymerase sigma factor RpoS,Sigma-38
|
E. coli
|
E. coli
|
|
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response. Controls, positively or negatively, the expression of several hundred genes, which are mainly involved in metabolism, transport, regulation and stress management.; Protects stationary phase cells from killing induced by endoribonuclease MazF. |
|
TMPH-02298
|
Urocortin-3 Protein, Human, Recombinant (His & SUMO)
UCN3,Stresscopin,Urocortin III,Urocortin-3
|
Human
|
E. coli
|
|
Suppresses food intake, delays gastric emptying and decreases heat-induced edema. Might represent an endogenous ligand for maintaining homeostasis after stress. |
|
TMPY-04260
|
p38 Protein, Human, Recombinant (His)
mitogen-activated protein kinase 14,CSPB1,PRKM14,RK,p38α,CSB...
|
Human
|
Baculovirus Insect Cells
|
|
MAPK14 contains 1 protein kinase domain and belongs to the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. MAPK14 can be detected in the brain, heart, placenta, pancreas, and skeletal muscle and it is expressed to a lesser extent in the lung, liver, and kidney. MAPK14 is activated by various environmental stresses ... |
|
TMPH-00653
|
LoiP Protein, E. coli, Recombinant (His)
loiP,Metalloprotease LoiP
|
E. coli
|
E. coli
|
|
Metalloprotease that cleaves substrates preferentially between Phe-Phe residues. Plays a role in response to some stress conditions. Seems to regulate the expression of speB. |
|
TMPH-00744
|
CsrA Protein, E. coli, Recombinant
Carbon storage regulator,csrA,Translational regulator CsrA
|
E. coli
|
E. coli
|
|
A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its f... |
|
TMPY-02043
|
PARK7/DJ-1 Protein, Human, Recombinant (His)
DJ1,HEL-S-67p,DJ-1,parkinson protein 7
|
Human
|
E. coli
|
|
Parkinson's disease locus DJ-1 (PARK7) is a differentially expressed transcript. DJ-1 plays a physiologic role in protection of erythroid cells from oxidant damage, a function unmasked in the context of oxidative stress. PARK7 belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress... |
|
TMPH-00641
|
YTFE Protein, E. coli, Recombinant (GST)
Regulator of cell morphogenesis and NO signaling,Iron-sulfur...
|
E. coli
|
E. coli
|
|
Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions. YTFE Protein, E. coli, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 51.9 kDa and the accession number is P69506. |
|
TMPH-03275
|
Cytoglobin Protein, Rat, Recombinant (His & Myc)
Stellate cell activation-associated protein,Stap,CYGB,Cytogl...
|
Rat
|
E. coli
|
|
May have a protective function during conditions of oxidative stress. May be involved in intracellular oxygen storage or transfer. Plays a role in the development of liver fibrosis. Has a peroxidase activity. |
|
TMPH-03443
|
GPX2 Protein, S. cerevisiae, Recombinant (His & Myc)
Glutathione peroxidase homolog 2,Glutathione peroxidase-like...
|
Saccharomyces cerevisiae
|
E. coli
|
|
Glutathione peroxidase-like protein that protects cells from phospholipid hydroperoxides and nonphospholipid peroxides during oxidative stress. Plays an important role in the oxidative stress-induced response in the presence of Ca(2+). Has peroxidase activity using preferentially thioredoxin as a reducing power. The redox state of the mitochondrial GPX2 is regulated by TRX1 and TRX2 (cytoplasmic thioredoxin), and by TRX3 (mitochondrial matrix thioredoxin). Involved in sporulation. GPX2 Protein, ... |
|
TMPY-03443
|
NDRG1 Protein, Human, Recombinant (His)
TARG1,PROXY1,RIT42,NDR1,DRG1,RTP,TDD5,CMT4D,CAP43,NMSL,N-myc...
|
Human
|
E. coli
|
|
NDRG1 gene is a member of the N-Myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. NDRG1 is a cytoplasmic protein involved in stress responses, hormone responses, cell growth, and differentiation. NDRG1 is necessary for p53-mediated caspase activation and apoptosis. Mutations in the NDRG1 gene are a cause of Charcot-Marie-Tooth disease type 4D, and expression of this gene may be a prognostic indicator for several types of cancer. NDRG1 is a stress-responsive pro... |
|
TMPH-03054
|
Asp f3 Protein, Neosartorya fumigata, Recombinant (His & SUMO)
|
Neosartorya fumigata
|
E. coli
|
|
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events. Required for virulence. |
|
TMPH-00094
|
HSP21, chloroplastic Protein, Arabidopsis thaliana, Recombinant (His & Myc)
25.3 kDa heat shock protein, chloroplastic,HSP21,Heat shock ...
|
Arabidopsis thaliana
|
E. coli
|
|
Chaperone protein required for seedling and chloroplast development under heat stress, probably by maintaining plastid-encoded RNA polymerase (PEP)-dependent transcription. HSP21, chloroplastic Protein, Arabidopsis thaliana, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 28.4 kDa and the accession number is P31170. |
|
TMPH-03053
|
Hydrophobin Protein, Neosartorya fumigata, Recombinant (B2M & His)
rodA,Rodlet protein,Hydrophobin
|
Neosartorya fumigata
|
E. coli
|
|
Cell wall protein regularly arranged in interwoven fascicules of clustered proteinaceous microfibrils, or rodlets, to form the outer spore coat protein. It is involved in resistance to environmental stress and may well be associated with conidial hydrophobicity. It is important in the morphogenesis of the dispersible conidia. |
|
TMPY-02390
|
SSPA Protein, E. coli, Recombinant (His)
ssp,pog
|
E. coli
|
E. coli
|
|
Stringent starvation protein A (ssPA), a member of the GST superfamily, is an RNA polymerase-associated transcriptional activator for the lytic development of phage P1 and is essential for stationary phase-induced acid tolerance of E. coli. It indicates that the flexible regions are not critical for SspA function, whereas the surface pocket is important for both transcriptional activation of the phage P1 late promoter and acid resistance of E. coli. SspA is known to be implicated in survival dur... |
|
TMPY-03627
|
CREB3L1 Protein, Human, Recombinant (aa 396-519, His)
OASIS,PSEC0238,cAMP responsive element binding protein 3-lik...
|
Human
|
HEK293 Cells
|
|
CREB3L1, also known as OASIS, is a cellular transcription factor synthesized as a membrane-bound precursor. It is a putative endoplasmic reticulum (ER) stress sensor in astrocytes with a mechanism of activation. OASIS mRNA expression was detected in pancreatic β-cell lines and rodent islets, and the expression level was up-regulated by ER stress-inducing compounds. CREB3L1 may have a role in pancreas development. CREB3L1 may also play an important role in limiting virus spread by inhibiting prol... |
|
TMPH-02153
|
Sulfiredoxin-1 Protein, Human, Recombinant (His & Myc)
SRXN1,Sulfiredoxin-1
|
Human
|
E. coli
|
|
Contributes to oxidative stress resistance by reducing cysteine-sulfinic acid formed under exposure to oxidants in the peroxiredoxins PRDX1, PRDX2, PRDX3 and PRDX4. Does not act on PRDX5 or PRDX6. May catalyze the reduction in a multi-step process by acting both as a specific phosphotransferase and a thioltransferase. |
|
TMPH-03721
|
IbpA Protein, Yersinia pestis bv. Antiqua, Recombinant (His)
Small heat shock protein IbpA,16 kDa heat shock protein A,ib...
|
Yersinia pestis
|
E. coli
|
|
Associates with aggregated proteins, together with IbpB, to stabilize and protect them from irreversible denaturation and extensive proteolysis during heat shock and oxidative stress. Aggregated proteins bound to the IbpAB complex are more efficiently refolded and reactivated by the ATP-dependent chaperone systems ClpB and DnaK/DnaJ/GrpE. Its activity is ATP-independent. |
|
TMPJ-01248
|
Cytoglobin/CYGB Protein, Human, Recombinant (His)
Stellate Cell Activation-Associated Protein,Cytoglobin,CYGB,...
|
Human
|
E. coli
|
|
Cytoglobin is a ubiquitously globin protein that belongs to the globin family. The highest expressed in heart, stomach, bladder and small intestine. CYGB acts a protector under conditions of oxidative stress. CYGB may be involved in intracellular oxygen storage or transfer, modulates oxygen and nitric oxide metabolism or scavenging free radicals within a cell. |
|
TMPH-02681
|
GPX7 Protein, Mouse, Recombinant (His & Myc)
Glutathione peroxidase 7,Gpx7
|
Mouse
|
E. coli
|
|
It protects esophageal epithelia from hydrogen peroxide-induced oxidative stress. It suppresses acidic bile acid-induced reactive oxigen species (ROS) and protects against oxidative DNA damage and double-strand breaks. GPX7 Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 26.7 kDa and the accession number is Q99LJ6. |
|
TMPH-03450
|
Nicotinamidase/PNC1 Protein, S. cerevisiae, Recombinant
Nicotinamide deamidase,PNC1,Nicotinamidase
|
Saccharomyces cerevisiae
|
E. coli
|
|
Catalyzes the deamidation of nicotinamide, an early step in the NAD(+) salvage pathway. Positively regulates SIR2-mediated silencing and longevity by preventing the accumulation of intracellular nicotinamide, an inhibitor of SIR2, during times of stress. Acts also on nicotinyl hydroxamate. Nicotinamidase/PNC1 Protein, S. cerevisiae, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 25.0 kDa and the accession number is P53184. |
|
TMPH-00072
|
2-Cys Prx A Protein, Arabidopsis thaliana, Recombinant (His)
Thioredoxin-dependent peroxiredoxin BAS1,2-Cys peroxiredoxin...
|
Arabidopsis thaliana
|
P. pastoris (Yeast)
|
|
Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides. May be an antioxidant enzyme particularly in the developing shoot and photosynthesizing leaf. 2-Cys Prx A Protein, Arabidopsis thaliana, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 24.4 kDa and the accession number is Q96291. |
|
TMPH-03449
|
Nicotinamidase/PNC1 Protein, S. cerevisiae, Recombinant (His)
Nicotinamidase,PNC1,Nicotinamide deamidase
|
Saccharomyces cerevisiae
|
E. coli
|
|
Catalyzes the deamidation of nicotinamide, an early step in the NAD(+) salvage pathway. Positively regulates SIR2-mediated silencing and longevity by preventing the accumulation of intracellular nicotinamide, an inhibitor of SIR2, during times of stress. Acts also on nicotinyl hydroxamate. Nicotinamidase/PNC1 Protein, S. cerevisiae, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 29.0 kDa and the accession number is P53184. |
|
TMPH-00085
|
SIZ1 Protein, Arabidopsis thaliana, Recombinant (His)
E3 SUMO-protein ligase SIZ1,SIZ1,E3 SUMO-protein transferase...
|
Arabidopsis thaliana
|
E. coli
|
|
E3 SUMO protein ligase involved in regulation processes. Mediates SUMO/ attachment to PHR1, a MYB transcriptional activator controlling the phosphate deficiency responses. Functions as an upstream negative regulator of salicylic acid (SA) accumulation and subsequent SA-mediated systemic acquired resistance (SAR) signaling. Probably not involved in jasmonic acid (JA)-mediated defense response. Participates in abiotic stress-induced sumoylation. Controls heat shock-induced SUMO1 and SUMO2 conjugat... |
|
TMPJ-00057
|
REG3G Protein, Human, Recombinant (hFc)
PAP-1B,REG3G,Regenerating islet-derived protein III-γ,Regene...
|
Human
|
HEK293 Cells
|
|
Pancreatitis-associated protein IB, Regenerating islet-derived protein III-gamma, is a secreted protein which contains 1 C-type lectin domain. It is expressed almost exclusively in the pancreas and also expressed in testis, but not found in small intestine. This protein might be a stress protein involved in the control of bacterial proliferation. |
|
TMPK-00696
|
PRAK/MAPKAPK5 Protein, Human, Recombinant (Strep-II)
MAPKAPK5,MK5,MAPKAP-K5,MK-5,MAPKAPK-5
|
Human
|
Baculovirus Insect Cells
|
|
The p38 mitogen-activated protein kinase (MAPK) pathway plays an important role in cellular responses to inflammatory stimuli and environmental stress. p38 regulated/activated protein kinase (PRAK, also known as mitogen-activated protein kinase activated protein kinase 5 [MAPKAPK5]) functions downstream of p38alpha and p38beta in mediating the signaling of the p38 pathway. |
|
TMPY-01588
|
ALDH7A1 Protein, Human, Recombinant (His)
ATQ1,aldehyde dehydrogenase 7 family, member A1,EPD,PDE
|
Human
|
E. coli
|
|
ALDH7A1 (Aldehyde dehydrogenase 7 family, member A1) is a member of subfamily 7 in the aldehyde dehydrogenase family. These enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. Mammalian ALDH7A1 is homologous to plant ALDH7B1 which protects against various forms of stress such as increased salinity, dehydration and treatment with oxidants or pesticides. In mammals, ALDH7A1 is known to play a primary role during lysine... |
|
TMPY-01769
|
4EBP1 Protein, Human, Recombinant (His)
4E-BP1,eukaryotic translation initiation factor 4E binding p...
|
Human
|
E. coli
|
|
The translational suppressor eIF4E binding protein-1, 4E-BP1 functions as a key regulator in cellular growth, differentiation, apoptosis and survival. The Eif4ebp1 gene, encoding 4E-BP1, is a direct target of a transcription factor activating transcription factor-4 (ATF4), a master regulator of gene expression in stress responses. 4E-BP1 is characterized by its capacity to bind specifically to eIF4E and inhibit its interaction with eIF4G. Phosphorylation of 4E-BP1 regulates eIF4E availability, a... |
|
TMPH-02313
|
RPGR Protein, Human, Recombinant (hFc)
RPGR,X-linked retinitis pigmentosa GTPase regulator
|
Human
|
HEK293 Cells
|
|
Could be a guanine-nucleotide releasing factor. Plays a role in ciliogenesis. Probably regulates cilia formation by regulating actin stress filaments and cell contractility. Plays an important role in photoreceptor integrity. May play a critical role in spermatogenesis and in intraflagellar transport processes. May be involved in microtubule organization and regulation of transport in primary cilia. |
|
TMPH-01502
|
Humanin Protein, Human, Recombinant (GST)
Humanin,Humanin mitochondrial,MT-RNR2
|
Human
|
E. coli
|
|
Plays a role as a neuroprotective factor. Protects against neuronal cell death induced by multiple different familial Alzheimer disease genes and amyloid-beta proteins in Alzheimer disease. Mediates its neuroprotective effect by interacting with a receptor complex composed of IL6ST/GP130, IL27RA/WSX1 and CNTFR. Also acts as a ligand for G-protein coupled receptors FPR2/FPRL1 and FPR3/FPRL2. Inhibits amyloid-beta protein 40 fibril formation. Also inhibits amyloid-beta protein 42 fibril formation.... |
|
TMPJ-00720
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TXNDC12 Protein, Human, Recombinant (His)
TLP19,ERp19,Thioredoxin Domain-Containing Protein 12,hTLP19,...
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Human
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HEK293 Cells
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Thioredoxin Domain-Containing Protein 12 belongs to the thioredoxin superfamily. In this family, proteins possess a thioredoxin fold with a consensus active-site sequence (CxxC) and have roles in redox regulation, defense against oxidative stress, refolding of disulfide-containing proteins, and regulation of transcription factors. TXNDC12 is widely expressed in many tissues and contains one thioredoxin domain. |
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