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Search Results for " endothelial "
Targets Recommended: Lipase

388

抑制剂 & 化合物

70

天然产物

2

化合物库

275

重组蛋白

7

同位素标记化合物

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Cat. No. Product Name
L5400 抗心血管疾病化合物库

1408 compounds
1408 种心血管疾病相关的生物活性小分子化合物的特有集合,用于高通量、高内涵筛选;
L2193 抗肝癌化合物库

1787 compounds
1787 种与肝癌相关的化合物,可以用于抗肝癌药物研发和药理研究;

化合物库

抗心血管疾病化合物库
Cat.No: L5400
Compounds: 1408
抗肝癌化合物库
Cat.No: L2193
Compounds: 1787
Cat. No. Product Name Target Signaling Pathways
T11199 Endothelial lipase inhibitor-1

Lipase Metabolism
Endothelial lipase inhibitor-1是有效,选择性的内皮脂肪酶抑制剂,IC50为 49 nM。
TP2195 Nitric Oxide Synthase (599-613) Blocking Peptide, Bovine Endothelial Cell

Others Others
Nitric Oxide Synthase (599-613) Blocking Peptide, Bovine Endothelial Cell (Ac-Pro-Tyr-Asn-Ser-Ser-Pro-Arg-Pro-Glu-Gln-His-Lys-Ser-Tyr-Lys-Cys) is a peptide that inhibits the function of NOSs as a result it blocks the production of NO. Because of the invol
T3566 SU5205

SU 5205

VEGFR Angiogenesis; Tyrosine Kinase/Adaptors
SU5205 是一种 VEGFR2 (FLK-1) 的抑制剂,其IC50=9.6 μM。
T4425 JK-P3

VEGFR Angiogenesis; Tyrosine Kinase/Adaptors
JK-P3 是广谱 VEGFR2抑制剂。它能够抑制 VEGF-A 刺激的 VEGFR2 激活和细胞内信号转导,也可阻碍内皮单层细胞迁移和血管生成,影响成纤维细胞生长因子受体激酶在体外的活性。它具有抗血管生成的作用。
T12598 Pz-1

VEGFR; c-RET Angiogenesis; Apoptosis; Tyrosine Kinase/Adaptors
Pz-1 是 VEGFR2 和 RET 酪氨酸激酶的抑制剂,可阻断 RET 刺激生长所需的血液供应。
T9724 VEGFR2-IN-2

Others Others
VEGFR2-IN-2 具有抗炎和镇痛活性。
T2446 KI8751

EGFR; VEGFR; FGFR; PDGFR; c-Kit Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
Ki8751 是一种有效的 VEGFR2 抑制剂,其 IC50=0.9 nM。
T9127 MYLS22

Others Others
MYLS22 是视神经萎缩 1 的选择性抑制剂。它通过影响 NFkB 活性和血管生成基因表达抑制血管生成,靶向作用于内皮细胞 OPA1 ,减少肿瘤的生长。
TQ0321 BIBF 1202

VEGFR Angiogenesis; Tyrosine Kinase/Adaptors
BIBF 1202是 BIBF 1120的羧酸盐代谢物。BIBF 1202抑制 VEGFR2激酶的 IC50值为62 nM。
T9979 VEGFR-2-IN-29

VEGFR Angiogenesis; Tyrosine Kinase/Adaptors
VEGFR-2-IN-29是一种 VEGFR2抑制剂。
TQ0041 Ningetinib Tosylate

VEGFR; c-Met/HGFR; TAM Receptor Angiogenesis; Tyrosine Kinase/Adaptors
Ningetinib Tosylate 是口服具有活力的、小分子酪氨酸激酶抑制剂,能够抑制 c-Met (IC50:6.7 nM),VEGFR2 (IC50:1.9 nM) 和 Axl (IC50<1.0 nM)。
T2419 BMS-794833

VEGFR; c-Met/HGFR Angiogenesis; Tyrosine Kinase/Adaptors
BMS794833 是一种 VEGFR2 和 Met 的抑制剂,它们的 IC50值分别为 15 和 1.7 nM。
T9929 Ramucirumab

VEGFR Angiogenesis; Tyrosine Kinase/Adaptors
Ramucirumab 是一种人 VEGFR-2 拮抗剂,具有抗实体瘤活性。它是人源化单克隆抗体,能够与 VEGFR-2 结合,阻碍 VEGFR 配体 VEGF-A,VEGF-C 和 VEGF-D 结合。
T6012 SAR131675

SAR 131675

VEGFR Angiogenesis; Tyrosine Kinase/Adaptors
SAR131675 是一种选择性的VEGFR3抑制剂,其IC50=23 nM。
T11520 GW806742X

MLK; VEGFR Angiogenesis; MAPK; Tyrosine Kinase/Adaptors
GW806742X 是ATP 模拟物,是MLKL 抑制剂,可结合 MLKL 假激酶结构域,Kd 值为 9.3μM。它对VEGFR2的IC50为 2 nM,延缓 MLKL 膜移位并抑制坏死。
T4534 BMS-309403

FABP Metabolism
BMS309403 是有效的、选择性脂肪细胞脂肪酸结合蛋白 aFABP 抑制剂。它可改善载脂蛋白 E 缺乏症小鼠和培养的人内皮细胞的内皮功能。它能够与蛋白质内部的脂肪酸结合口袋相互作用,竞争性地抑制内源性脂肪酸的结合。
T16975 TAK-593

VEGFR; PDGFR Angiogenesis; Tyrosine Kinase/Adaptors
TAK-593 是一种 VEGFR2 和 PDGFR 抑制剂,能够作用于VEGFR1 (IC50:3.2 nM)、VEGFR2 (IC50:0.95 nM)、VEGFR3 (IC50:1.1 nM)、PDFGRα (IC50:4.3 nM)、PDFGRβ (IC50:13 nM)。
T4288 hVEGF-IN-1

VEGFR Angiogenesis; Tyrosine Kinase/Adaptors
hVEGF-IN-1 是一种喹唑啉衍生物,可以特异性结合内部核糖体进入位点 A 中富含 G 的序列,并会使 G-四链体结构不稳定。在 SPR 实验中,它与 IRES-A (WT) 结合的Kd 值为 0.928 μM。它能够抑制VEGF-A 蛋白表达,阻止肿瘤细胞迁移,抑制肿瘤生长。
T2064 Semaxinib

司马沙尼,SU5416

VEGFR Angiogenesis; Tyrosine Kinase/Adaptors
Semaxinib (SU5416) 是一种选择性的 VEGFR(Flk-1/KDR) 抑制剂,其 IC50=1.23 μM。
T2642 PD173074

Apoptosis; EGFR; VEGFR; FGFR; IGF-1R; Src Angiogenesis; Apoptosis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
PD173074 是一种 FGFR1抑制剂,IC50为 25 nM。它也可抑制 VEGFR2活性,IC50值为 100-200 nM。
T2656 Fruquintinib

HMPL-013,呋喹替尼

VEGFR Angiogenesis; Tyrosine Kinase/Adaptors
Fruquintinib (HMPL-013) 是一种选择性的VEGFR 1/2/3抑制剂,它们的IC50值分别为33 nM、0.5 nM、35 nM。
T5475 ZD-4190

EGFR; VEGFR Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
ZD-4190 是血管内皮细胞生长因子受体 2 (VEGFR2) 和表皮生长因子受体 (EGFR) 信号传导的抑制剂,用于治疗癌症。
T6036 Brivanib

BMS-540215,布立尼布

EGFR; VEGFR; FGFR; Autophagy Angiogenesis; Autophagy; JAK/STAT signaling; Tyrosine Kinase/Adaptors
Brivanib (BMS-540215) 是一种针对 VEGFR2 的 ATP 竞争性抑制剂,IC50 为 25 nM。它对 VEGFR-1 和 FGFR-1 具有中等效力,对 VEGFR2 的选择性是对 PDGFR-β 的 240 倍。
T1656 Vandetanib

ZD6474,凡德他尼

Apoptosis; EGFR; VEGFR; Autophagy Angiogenesis; Apoptosis; Autophagy; JAK/STAT signaling; Tyrosine Kinase/Adaptors
Vandetanib (ZD6474) 是一种具有口服活性的VEGFR2/KDR 酪氨酸激酶抑制剂,IC50值为40 nM。它也抑制VEGFR3/FLT4和EGFR/HER1,IC50值分别为110和500 nM。
T9928 Ranibizumab

VEGFR Angiogenesis; Tyrosine Kinase/Adaptors
Ranibizumab 是一种人源化单克隆抗体片段,旨在靶向和抑制血管内皮生长因子 (VEGF),包括 VEGF110、VEGF121 和 VEGF165。 Ranibizumab 选择性靶向和中和 VEGF-A 同工型的能力使其成为湿性年龄相关性黄斑变性 (AMD) 研究和治疗策略的重要组成部分。
T3691 (Rac)-SAR131675

SAR131675

VEGFR Angiogenesis; Tyrosine Kinase/Adaptors
(Rac)-SAR131675 是一种有效的、选择性的VEGFR3抑制剂,其IC50=23 nM。
T7945 SU14813

VEGFR; PDGFR; c-Kit Angiogenesis; Tyrosine Kinase/Adaptors
SU14813 是一种多靶点受体酪氨酸激酶抑制剂,能够抑制 VEGFR2 (IC50:50 nM),VEGFR1 (IC50:2 nM),PDGFRβ (IC50:4 nM),KIT (IC50:15 nM)。
T6517 Golvatinib

E-7050,戈伐替尼

VEGFR; c-Met/HGFR Angiogenesis; Tyrosine Kinase/Adaptors
Golvatinib (E-7050) 是一种 c-Met (IC50:14 nM) 和 VEGFR2 (IC50:16 nM) 的双重抑制剂。
T5466 Tyrosine kinase-IN-1

VEGFR; FGFR; FLT; PDGFR Angiogenesis; Tyrosine Kinase/Adaptors
Tyrosine kinase-IN-1是一种多靶点酪氨酸激酶抑制剂,能够抑制KDR (IC50:4 nM),Flt-1 (IC50:20 nM),FGFR1 (IC50:4 nM) 和 PDGFRα (IC50:2 nM)。
T3569 SU5214

SU 5214

VEGFR; Tyrosinase Angiogenesis; Proteases/Proteasome; Tyrosine Kinase/Adaptors
SU5214 (SU 5214) 是 VEGFR2 抑制剂,IC50值为 14.8 µM(FLK-1) 和 36.7 µM (EGFR)。
T3599 BFH772

BFH-722

VEGFR Angiogenesis; Tyrosine Kinase/Adaptors
BFH772 是 VEGFR2抑制剂(IC50:3 nM),具有口服活性。
T21593 AAL-993

VEGFR Angiogenesis; Tyrosine Kinase/Adaptors
AAL-993 是口服有效的VEGFR 选择性抑制剂,抑制 VEGFR1、VEGFR2 和 VEGFR3 的IC50分别为 130 nM、23 nM 和 18 nM,对其他酪氨酸激酶的抑制作用较弱。AAL-993 具有抗血管生成和抗肿瘤的活性。
T6996 SU 5402

SU5402

VEGFR; FGFR; PDGFR Angiogenesis; Tyrosine Kinase/Adaptors
SU 5402 是多靶点受体酪氨酸激酶抑制剂,能够抑制VEGFR2 (IC50:20 nM),FGFR1 (IC50:30 nM),PDGFRβ (IC50:510 nM)。
T9473 4SC-203

FLT Angiogenesis; Tyrosine Kinase/Adaptors
4SC-203 是一种具有潜在的抗肿瘤活性的多激酶抑制剂。它对 FLT3/STK1、 FLT3 的突变形式以及 VEGFRs 具有选择性抑制作用。
T7123 AMG-47a

VEGFR; p38 MAPK; JAK; Src Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; MAPK; Stem Cells; Tyrosine Kinase/Adaptors
AMG-47a 是具有口服活性的 Lck 抑制剂,IC50值为 0.2 nM。它具有抗炎作用,对 VEGF2、p38α、p38α、Jak3、MLR 和 IL-2的 IC50值分别为 1、3、72、30 和 21 nM。
T4026 SU5408

VEGFR2 Kinase Inhibitor I

VEGFR Angiogenesis; Tyrosine Kinase/Adaptors
SU5408 (VEGFR2 Kinase Inhibitor I) 是一种可渗透细胞的VEGFR2激酶抑制剂,其IC50=70 nM。
T1754 ZM 306416

CB 676475

VEGFR; Bcr-Abl; Src Angiogenesis; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors
ZM 306416 (CB 676475) 是一种 VEGFR 的有效抑制剂,能够抑制 KDR (IC50:0.1 μM) 和 Flt (IC50:2 μM),也是一种 EGFR 的抑制剂(IC50<10 nM)。
T21807 INCA-6

Triptycene-1,4-quinone

Others Others
INCA-6 (Triptycene-1,4-quinone) 是细胞渗透性的 NFAT 抑制剂。INCA-6 通过特异性阻断 NFAT 底物靶向钙调神经磷酸酶位点,有效抑制calcineurin (CN)-NFAT 信号传导。
T7611 ODM-203

VEGFR; FGFR Angiogenesis; Tyrosine Kinase/Adaptors
ODM-203 是 FGFR 和 VEGFR 家族的抑制剂,具有显著的抗肿瘤活性,能够诱导抗肿瘤免疫。
T15185 Lucitanib

E-3810,德立替尼

VEGFR; FGFR Angiogenesis; Tyrosine Kinase/Adaptors
Lucitanib (E-3810) 是 VEGFR 和 FGFR 的双重抑制剂,有效和选择性地抑制VEGFR1 (IC50:7 nM),VEGFR2 (IC50:25 nM),VEGFR3 (IC50:10 nM),FGFR1 (IC50:17.5 nM),FGFR2 (IC50:82.5 nM)。
T6166 Telatinib

Bay 57-9352,替拉替尼

VEGFR; PDGFR; c-Kit Angiogenesis; Tyrosine Kinase/Adaptors
Telatinib (Bay 57-9352) 是一种口服具有活力的,小分子的 VEGFR2,VEGFR3,PDGFα 和 c-Kit 抑制剂,它们的 IC50 值分别为6,4,15,1 nM。
T6335 Tie2 kinase inhibitor 1

Tie2 kinase inhibitor

Tie-2 Tyrosine Kinase/Adaptors
Tie2 kinase inhibitor 1 (Tie2 kinase inhibitor) 是Tie2激酶选择性抑制剂9IC50:250 nM),具有抗癌作用。
T7506 Yoda 1

Piezo Channel Membrane transporter/Ion channel
Yoda 1 是Piezo1激动剂,能够激活纯化的 Piezo1 通道。
TQ0317 R1530

R-1530,R 1530

VEGFR; FGFR; FLT; PDGFR Angiogenesis; Tyrosine Kinase/Adaptors
R1530 是一种多激酶抑制剂,具有抗肿瘤和抗血管生成活性。它是具有口服活性的有丝分裂/血管生成高效双重作用抑制剂, 抑制 VGFR2、FGFR1作用的 IC50分别为 10 nM 和 28 nM。
T2288 Motesanib

AMG 706,莫特塞尼,莫替沙尼

VEGFR; c-Kit Angiogenesis; Tyrosine Kinase/Adaptors
Motesanib (AMG 706) 是有效的、ATP 竞争性的 VEGFR1/2/3 的抑制剂,其IC50值为 2 nM/3 nM/6 nM,与对 Kit 的选择性相似,是 PDGFR 和 Ret 的 10 倍多。
T6296 RAF265

CHIR-265

Apoptosis; Raf; VEGFR; Autophagy Angiogenesis; Apoptosis; Autophagy; MAPK; Tyrosine Kinase/Adaptors
RAF265 (CHIR-265) 是一种 RAF/VEGFR2抑制剂。
T3570 SU4312

SU 4312,NSC 86429

VEGFR; PDGFR Angiogenesis; Tyrosine Kinase/Adaptors
NSC-86429 是一种 (Z)-SU4312 (SU 4312) 和 (E)-SU4312 的外消旋体。其中(Z)-SU4312 能够抑制 PDGFR 和 FLK-1。(E)-SU4312 能够抑制 PDGFR, FLK-1, EGFR, HER-2, 和 IGF-1R。
T5194 SPHINX31

Serine/threonin kinase Cell Cycle/Checkpoint; Metabolism
SPHINX31 是丝氨酸/富含精氨酸的蛋白激酶1的选择性抑制剂,其IC50值为 5.9 nM。它有效抑制丝氨酸/丰富精氨酸的剪接因子1 磷酸化,有用于局部新生血管性眼病的研究潜力。
T8496 MAZ51

Apoptosis; VEGFR Angiogenesis; Apoptosis; Tyrosine Kinase/Adaptors
MAZ51 是一种 VEGFR-3酪氨酸激酶的选择性抑制剂。它抑制 VEGF-C 诱导的 VEGFR-3 激活,而没有阻断 VEGF-C 介导的 VEGFR2 刺激。它阻止增殖并诱导多种肿瘤细胞凋亡,具有抗肿瘤活性。
TQ0021 Ningetinib

CT-053,CT053PTSA,宁格替尼

VEGFR; c-Met/HGFR; TAM Receptor Angiogenesis; Tyrosine Kinase/Adaptors
Ningetinib (CT-053) 是口服具有活力的、小分子酪氨酸激酶抑制剂,能够抑制 c-Met (IC50:6.7 nM),VEGFR2 (IC50:1.9 nM) 和 Axl (IC50<1.0 nM)。

化合物

Endothelial lipase inhibitor-1
Cat.No: T11199
Synonym:
Target: Lipase
Nitric Oxide Synthase (599-613) Blocking Peptide, Bovine Endothelial Cell
Cat.No: TP2195
Synonym:
Target: Others
SU5205
Cat.No: T3566
Synonym: SU 5205
Target: VEGFR
JK-P3
Cat.No: T4425
Synonym:
Target: VEGFR
Pz-1
Cat.No: T12598
Synonym:
Target: VEGFR, c-RET
VEGFR2-IN-2
Cat.No: T9724
Synonym:
Target: Others
KI8751
Cat.No: T2446
Synonym:
Target: EGFR, VEGFR, FGFR, PDGFR, c-Kit
MYLS22
Cat.No: T9127
Synonym:
Target: Others
BIBF 1202
Cat.No: TQ0321
Synonym:
Target: VEGFR
VEGFR-2-IN-29
Cat.No: T9979
Synonym:
Target: VEGFR
Ningetinib Tosylate
Cat.No: TQ0041
Synonym:
Target: VEGFR, c-Met/HGFR, TAM Receptor
BMS-794833
Cat.No: T2419
Synonym:
Target: VEGFR, c-Met/HGFR
Ramucirumab
Cat.No: T9929
Synonym:
Target: VEGFR
SAR131675
Cat.No: T6012
Synonym: SAR 131675
Target: VEGFR
GW806742X
Cat.No: T11520
Synonym:
Target: MLK, VEGFR
BMS-309403
Cat.No: T4534
Synonym:
Target: FABP
TAK-593
Cat.No: T16975
Synonym:
Target: VEGFR, PDGFR
hVEGF-IN-1
Cat.No: T4288
Synonym:
Target: VEGFR
Semaxinib
Cat.No: T2064
Synonym: 司马沙尼,SU5416
Target: VEGFR
PD173074
Cat.No: T2642
Synonym:
Target: Apoptosis, EGFR, VEGFR, FGFR, IGF-1R, Src
Fruquintinib
Cat.No: T2656
Synonym: HMPL-013,呋喹替尼
Target: VEGFR
ZD-4190
Cat.No: T5475
Synonym:
Target: EGFR, VEGFR
Brivanib
Cat.No: T6036
Synonym: BMS-540215,布立尼布
Target: EGFR, VEGFR, FGFR, Autophagy
Vandetanib
Cat.No: T1656
Synonym: ZD6474,凡德他尼
Target: Apoptosis, EGFR, VEGFR, Autophagy
Ranibizumab
Cat.No: T9928
Synonym:
Target: VEGFR
(Rac)-SAR131675
Cat.No: T3691
Synonym: SAR131675
Target: VEGFR
SU14813
Cat.No: T7945
Synonym:
Target: VEGFR, PDGFR, c-Kit
Golvatinib
Cat.No: T6517
Synonym: E-7050,戈伐替尼
Target: VEGFR, c-Met/HGFR
Tyrosine kinase-IN-1
Cat.No: T5466
Synonym:
Target: VEGFR, FGFR, FLT, PDGFR
SU5214
Cat.No: T3569
Synonym: SU 5214
Target: VEGFR, Tyrosinase
BFH772
Cat.No: T3599
Synonym: BFH-722
Target: VEGFR
AAL-993
Cat.No: T21593
Synonym:
Target: VEGFR
SU 5402
Cat.No: T6996
Synonym: SU5402
Target: VEGFR, FGFR, PDGFR
4SC-203
Cat.No: T9473
Synonym:
Target: FLT
AMG-47a
Cat.No: T7123
Synonym:
Target: VEGFR, p38 MAPK, JAK, Src
SU5408
Cat.No: T4026
Synonym: VEGFR2 Kinase Inhibitor I
Target: VEGFR
ZM 306416
Cat.No: T1754
Synonym: CB 676475
Target: VEGFR, Bcr-Abl, Src
INCA-6
Cat.No: T21807
Synonym: Triptycene-1,4-quinone
Target: Others
ODM-203
Cat.No: T7611
Synonym:
Target: VEGFR, FGFR
Lucitanib
Cat.No: T15185
Synonym: E-3810,德立替尼
Target: VEGFR, FGFR
Telatinib
Cat.No: T6166
Synonym: Bay 57-9352,替拉替尼
Target: VEGFR, PDGFR, c-Kit
Tie2 kinase inhibitor 1
Cat.No: T6335
Synonym: Tie2 kinase inhibitor
Target: Tie-2
Yoda 1
Cat.No: T7506
Synonym:
Target: Piezo Channel
R1530
Cat.No: TQ0317
Synonym: R-1530,R 1530
Target: VEGFR, FGFR, FLT, PDGFR
Motesanib
Cat.No: T2288
Synonym: AMG 706,莫特塞尼,莫替沙尼
Target: VEGFR, c-Kit
RAF265
Cat.No: T6296
Synonym: CHIR-265
Target: Apoptosis, Raf, VEGFR, Autophagy
SU4312
Cat.No: T3570
Synonym: SU 4312,NSC 86429
Target: VEGFR, PDGFR
SPHINX31
Cat.No: T5194
Synonym:
Target: Serine/threonin kinase
MAZ51
Cat.No: T8496
Synonym:
Target: Apoptosis, VEGFR
Ningetinib
Cat.No: TQ0021
Synonym: CT-053,CT053PTSA,宁格替尼
Target: VEGFR, c-Met/HGFR, TAM Receptor
Cat. No. Product Name Target Signaling Pathways
T8213 Isolinderalactone

NOS; STAT Immunology/Inflammation; JAK/STAT signaling; Stem Cells
Isolinderalactone 具有抗炎和抗癌能力,具有中等的 iNOS 抑制活性,IC50 值为 0.30 uM。
T3881 Vaccarin

Integrin; Akt; PERK; AMPK Apoptosis; Chromatin/Epigenetic; Cytoskeletal Signaling; PI3K/Akt/mTOR signaling
Vaccarin 是从王不留行中提取的一种黄酮糖苷,可显著促进伤口愈合以及伤口部位的内皮和成纤维细胞增殖。它通过激活 AMPK 信号通路改善胰岛素抵抗和脂肪变性。
T4A2456 Gamabufotalin

Gamabufagin,日本蟾蜍毒苷元

COX Immunology/Inflammation; Neuroscience
Gamabufotalin (Gamabufagin) 是一种蟾蜍甾烯,存在于蟾酥中。它稳定性高,毒性低,被广泛用于癌症的研究。
TN4417 Larixyl acetate

Others Others
Larixyl acetate 是一种生物活性化学物质。
T17280 (Z)-Guggulsterone

Apoptosis; VEGFR; Akt Angiogenesis; Apoptosis; Cytoskeletal Signaling; PI3K/Akt/mTOR signaling; Tyrosine Kinase/Adaptors
(Z)-Guggulsterone 是印度阿育吠陀药用植物Commiphora mukul 的成分,可通过引起细胞凋亡来抑制人前列腺癌细胞的生长,还可通过抑制VEGF-VEGF-R2-Akt 信号传导轴来抑制血管生成。
T2906 Tanshinone IIA

丹参酮IIA,Tanshinone B,Dan Shen ketone

VEGFR Angiogenesis; Tyrosine Kinase/Adaptors
Tanshinone IIA (Tanshinone B) 是红根丹参根系中的一种主要组合物。它能够利用靶向 VEGF/VEGFR2的蛋白激酶结构域,抑制血管生成。
T3S0153 Xanthatin

苍耳亭,叶黄制菌素

Apoptosis; VEGFR; Lipoxygenase; Wnt/beta-catenin; Antibacterial Angiogenesis; Apoptosis; Cytoskeletal Signaling; Metabolism; Microbiology/Virology; Stem Cells; Tyrosine Kinase/Adaptors
Xanthatin 是一种从Xanthium strumarium 叶子中提取的天然产物,可诱导细胞凋亡。它抑制布鲁氏菌的IC50值为 2.63 μg/ mL,对寄生虫特异性锥虫硫磷还原酶具有不可逆的弱抑制作用。它通过抑制PGE2的合成和 5-脂氧合酶的活性而显示出抗炎活性。
T3673 Mollugin

大叶茜草素,Rubimaillin

HER; JAK Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells; Tyrosine Kinase/Adaptors
Mollugin (Rubimaillin) 是Rubia cordifolia L.中主要的生物活性成分。它能通过 p38-Smad 信号通路增强 BMP-2 的成骨作用。它通过抑制 TNF-α 诱导的 NF-κB 激活起抗癌疗效。
T7203 Oglufanide

奥谷法奈,L-Glutamyl-L-tryptophan,H-Glu-Trp-OH

VEGFR; HCV Protease; Endogenous Metabolite Angiogenesis; Metabolism; Microbiology/Virology; Proteases/Proteasome; Tyrosine Kinase/Adaptors
Oglufanide (H-Glu-Trp-OH) 是一种从小牛胸腺中分离出来的二肽免疫调节剂,可抑制血管内皮生长因子,可刺激细胞内细菌感染和对丙型肝炎病毒的免疫反应。
T1152 Albendazole

SKF-62979,阿苯达唑

HIF/HIF Prolyl-Hydroxylase; Microtubule Associated; Antibiotic; Parasite Chromatin/Epigenetic; Cytoskeletal Signaling; Metabolism; Microbiology/Virology
Albendazole (SKF-62979) 是一种广谱抗寄生虫剂,具有高效,低宿主毒性的特点。 它用于研究人类和动物的胃肠道寄生虫。
T13108 Pamufetinib

H2OL3Q4XRD,4-(2-Fluoro-4-(3-(2-phenylacetyl)thioureido)phenoxy)-7-methoxy-N-methylquinoline-6-carboxamide,TAS-115

VEGFR; c-Met/HGFR Angiogenesis; Tyrosine Kinase/Adaptors
Pamufetinib (TAS-115) 是VEGFR 和c-Met/HGFR 抑制剂,能够抑制 rVEGFR2 (IC50:30 nM)和 rMET (IC50:32 nM)的活性。
TN2019 Orobol

3'-Hydroxygenistein,3’,4’,5,7-tetrahydroxy-isoflavon,3',4',5,7-四羟基异黄酮

BCL; Caspase; PI3K Apoptosis; PI3K/Akt/mTOR signaling; Proteases/Proteasome
Orobol (3’,4’,5,7-tetrahydroxy-isoflavon) 是酪氨酸特异性蛋白激酶和磷脂酰肌醇转换的抑制剂。Orobol 抑制 PI3K,对 PI3K α/β/γ/K/δ 的 IC50 为 3.46-5.27 μM。 Orobol 具有抗皮肤老化和抗肥胖的作用。
T1205 Chloramphenicol

Chlornitromycin,Levomycetin,Chloromycetin,氯霉素

ribosome; HIF/HIF Prolyl-Hydroxylase; Antibacterial; Antibiotic Chromatin/Epigenetic; Metabolism; Microbiology/Virology
Chloramphenicol (Chloromycetin) 是一种广谱抗生素,有效抑制细菌蛋白质生物合成。它主要作用于细菌 70S 核糖体的 50S 亚基,对肽基转移酶有活性,抑制肽键的形成。
TWA2417 Sodium taurocholate

牛黄胆酸钠(牛胆酸钠,牛胆酸钠盐,牛磺膽酸鈉,牛磺胆酸钠,牛磺胆酸钠盐,牛胆酸钠水合物,水合牛磺胆酸钠,牛胆酸钠(混合物),牛黄胆酸钠(水合),牛磺胆酸钠(标准品)),Taurocholate Sodium

Others Others
Sodium taurocholate (Taurocholate Sodium) hydrate 具有显著的生物学效应,例如通过上调 VEGF-A 的表达抑制肝动脉结扎所致的胆道损伤。对免疫系统具有一定的调节作用。
T14055 5Z-7-Oxozeaenol

FR148083,L783279,LL-Z 1640-2

VEGFR; FLT; MEK; MAPK; PDGFR; Antibiotic; Src Angiogenesis; MAPK; Microbiology/Virology; Tyrosine Kinase/Adaptors
5Z-7-Oxozeaenol (FR148083) 是一种天然抗原生动物抑制剂,不可逆的选择性抑制 TAK1和 VEGF-R2,IC50值分别为 8 nM 和 52 nM。
T5235 5-Methoxy-DL-tryptophan

Others; Endogenous Metabolite Metabolism; Others
5-Methoxy-DL-tryptophan 是内源性代谢产物的一种。
T5233 N-Methylnicotinamide

N'-Methylnicotinamide,Nicotinic Acid Methylamide,N-Methylpyridine-3-carboxamide,N-甲基烟酰胺

Others; Endogenous Metabolite Metabolism; Others
N-Methylnicotinamide 是内源性代谢产物的一种,可改善内皮功能障碍。
T3427 Polydatin

Piceid,虎杖苷,Polydotin Peceid

Apoptosis; Mitophagy; NF-κB; Autophagy Apoptosis; Autophagy; NF-κB
Polydatin (Piceid) 是从传统中药虎杖根中提取的一种天然产物,在多个实验模型中具有抗炎作用。它可抑制 G6PD,并诱导氧化和内质网应激。
T38248 2-Ethylpyrazine

Endogenous Metabolite; NO Synthase Immunology/Inflammation; Metabolism
2-Ethylpyrazine 存在与烘焙后的咖啡豆中,是一种挥发性化合物 。2-Ethylpyrazine 通过内皮衍生的松弛因子的活动诱导血管舒张。2-Ethylpyrazine 通过内皮内皮NO 合酶的作用激活NO 合成。2-Ethylpyrazine 通过诱导NO 释放和增加外周血流量来诱导血管舒张。
T2220 2-Methoxyestradiol

2-甲氧雌二醇,二甲氧基雌二醇,NSC-659853,2-MeOE2,2-ME2

Apoptosis; Reactive Oxygen Species; Microtubule Associated; Endogenous Metabolite; HIF; Autophagy Angiogenesis; Apoptosis; Autophagy; Chromatin/Epigenetic; Cytoskeletal Signaling; Immunology/Inflammation; Metabolism; NF-κB
2-Methoxyestradiol (2-ME2) 是一种口服生物可利用的雌二醇代谢物,具有抗肿瘤活性。它通过减少内皮细胞增殖和诱导内皮细胞凋亡来抑制血管生成,也可破坏微管的稳定。它可诱导半胱天冬酶活化,导致细胞周期停滞在 G2 期、DNA 断裂和细胞凋亡。
TN1421 Bacopaside II

Apoptosis Apoptosis
Bacopaside II 是药用植物Bacopa monnieri 的提取物,可阻断Aquaporin-1 (AQP1)水通道并阻碍表达 AQP1 的细胞迁移,还诱导细胞周期停滞和细胞凋亡。
TN1918 Medicarpin

美迪紫檀素

Apoptosis; BCL; ROS; JNK Apoptosis; Immunology/Inflammation; MAPK
Medicarpin 是从紫花苜蓿中分离出的一种类黄酮。它通过调节 P-gp 介导的药物外流,诱导白血病 P388 细胞凋亡并克服多药耐药性。
T3864 Erianin

BCL; Antibacterial Apoptosis; Microbiology/Virology
Erianin 能抑制吲哚胺-2,3-双加氧酶诱导的肿瘤血管生成,可用作退烧药和止疼剂。
T6S1373 Casticin

Quercetagetin 3,6,7,4'-Tetramethyl Ether,Vitexicarpin,蔓荆子黄素

STAT JAK/STAT signaling; Stem Cells
Casticin (Vitexicarpin) 是从蔓荆子中得到的一种甲氧基黄酮,可抑制STAT3的活化,具有抗有丝分裂和抗炎活性。
T67708 Thiolutin

Acetopyrrothin

Antibacterial; Antibiotic Microbiology/Virology
Thiolutin (Acetopyrrothin) 是一种内皮细胞粘附抑制剂,由链霉菌产生。 Thiolutin 具有抗生素和抗血管生成特性。 Thiolutin 可快速诱导 Hsp27 的磷酸化。
T2810 (20S)-Protopanaxatriol

原人参三醇,20(S)-APPT,20 (S)-原人参三醇,g-PPT

Apoptosis; Estrogen Receptor/ERR; Glucocorticoid Receptor; Estrogen/progestogen Receptor; Liver X Receptor Apoptosis; Endocrinology/Hormones; Metabolism
(20S)-Protopanaxatriol (g-PPT) 是人参皂苷的代谢物,通过糖皮质激素受体和雌激素受体起作用,同时为LXRα的抑制剂,具有广泛的抗癌活性。
T17056 Tetrahydrobiopterin

Sapropterin,BH4,(Rac)-Sapropterin

NOS; Endogenous Metabolite Immunology/Inflammation; Metabolism
Tetrahydrobiopterin (BH4) 是芳香族氨基酸羟化酶的辅因子, 也是一氧化氮合酶 (NOS) 的必需辅因子,可用于研究如高血压、高胆固醇血症、糖尿病等内皮功能障碍。
T3S0137 Bavachalcone

Antibacterial; Antibiotic Microbiology/Virology
Bavachalcone 是从补骨脂中分离的化合物,广泛用于中药,具有抗生素和抗癌等活性。
T2836 Isorhamnetin

3-methylquercetin,3'-Methylquercetin,Isorhamnetol,异鼠李素,3'-Methoxyquercetin

MEK; PI3K; Endogenous Metabolite MAPK; Metabolism; PI3K/Akt/mTOR signaling
Isorhamnetin (3-methylquercetin) 是从中草药沙棘中提取的一种类黄酮,可通过抑制MEK1和PI3K 来抑制皮肤癌。
T2S0886 Terrestrosin D

Apoptosis; Others Apoptosis; Others
Terrestrosin D 是从刺蒺藜中提取得到一种的甾体皂苷,可诱导细胞周期阻滞和癌细胞凋亡,具有抗血管生成的活性。
TN6551 Tectoruside

Antioxidant oxidation-reduction
Tectoruside 是一种从鸢尾和豹纹百合中提取得到的酚酸糖苷,具有抗诱变和抗氧化活性,通过靶向ROS相关炎症和IRS-1通路来减弱棕榈酸酯诱导的内皮胰岛素抵抗。Tectoruside 可用于研究癌症。
TCS1704 Artemitin

艾黄素,Artemetin,Artemisetin,Erianthin

Antioxidant oxidation-reduction
Artemitin (Erianthin) 是一种存在于翼齿六棱菊中的天然黄酮,具有抗氧化、抗炎、抗病毒活性。
TN1895 Luteolinidin chloride

CD38 Immunology/Inflammation
Luteolinidin chloride 是天然的脱氧花青素,分离自苔藓和蕨类植物中。它是一种有效的 CD38 抑制剂,可以保留 eNOS 功能并预防体内内皮功能障碍,同时可以保护心脏免受 I/R 损伤。
T5120 Rhamnose

6-Deoxyhexopyranose,L-鼠李糖,6-Deoxy-L-mannose,alpha-L-Rhamnose

Calcium Channel; Endogenous Metabolite Membrane transporter/Ion channel; Metabolism
alpha-L-Rhamnose (6-Deoxy-L-mannose) 是存在植物和细菌中的一种单糖。Rhamnose- 免疫原连接物能被用于免疫疗法。Rhamnose 能通过胞外途径穿过上皮细胞,能够作为肠吸收的标志。
T20793 Magnesium Lithospermate B

丹參酸B鎂,Monomethyl lithospermate B,丹参酸 B 镁,Lithospermate B

Others Others
Magnesium Lithospermate B 是一种咖啡酸四聚体的衍生物,从Salviae miltiorrhizae 中提取得到。它能够抑制神经炎症并减轻神经变性。它被广泛用于心血管疾病的研究,并且可以防止葡萄糖引起的细胞内氧化损伤。
TN5171 Tricetin

Apoptosis; Others; Nrf2 Apoptosis; Immunology/Inflammation; Others
Tricetin 是一种从石榴中分离出的类黄酮。Tricetin 是 Keap1-Nrf2 蛋白相互作用(PPI)的强效竞争性抑制剂,通过激活 Nrf2/HO-1 信号通路和阻止线粒体依赖性细胞凋亡通路,保护帕金森病患免受 6-OHDA 诱导的神经毒性的影响。Tricetin 通过 Akt/GSK-1β途径抑制鼻咽癌的迁移和指示性蛋白酶早老素-1(PS-1)表达。Tricetin 抑制由Egr-1介导的氧化LDL 诱导的内皮炎症,保护大鼠软骨细胞免受IL-1β诱导的炎症和细胞凋亡。
T6S1256 Ruscogenin

NOS; NF-κB; NOD-like Receptor (NLR) Immunology/Inflammation; NF-κB
Ruscogenin 是一种重要甾体皂苷元,提取自麦冬。它能够抑制 TXNIP/NLRP3炎症体激活和 MAPK 途径,改善脑缺血诱导的血脑屏障功能障碍,具有显著抗血栓、抗炎作用。
T7044 Norepinephrine

去甲肾上腺素,Levophed,Levonoradrenaline,Aktamin,Nor-Epirenan,Levonor,Arterenol

MMP; Endogenous Metabolite; Adrenergic Receptor; Autophagy Autophagy; GPCR/G Protein; Metabolism; Neuroscience; Proteases/Proteasome
Norepinephrine (Levophed) 属于生物碱类天然产物,是一种神经递质,一种肾上腺素能受体 (AR) 的激动剂,对 α1、α2 和 β1 AR 具有激活活性。Norepinephrine 被用作抗休克的血管活性剂。
T3414 Morroniside

莫诺苷,奎宁树

Apoptosis; MMP; Pyroptosis Apoptosis; Immunology/Inflammation; Proteases/Proteasome
Morroniside 通过抑制神经元凋亡和 MMP9/2 的表达从而发挥神经保护作用,可作为 db/db 小鼠肝脏炎症反应和脂质代谢的调节剂。它通过抑制高血糖和氧化应激表现出对糖尿病肾损伤和人脐静脉内皮细胞的保护作用。
T3402 20(S)-Ginsenoside Rg3

20(S)-人参皂苷 Rg3,人参皂苷 Rg3,20(S)-Ginsenoside-Rg3,Rg3,20S-Ginsenoside Rg3,Ginsenoside Rg3,S-Ginsenoside Rg3

EGFR; Beta Amyloid; Potassium Channel; NF-κB; COX; Sodium Channel; Endogenous Metabolite Angiogenesis; Immunology/Inflammation; JAK/STAT signaling; Membrane transporter/Ion channel; Metabolism; Neuroscience; NF-κB; Tyrosine Kinase/Adaptors
20(S)-Ginsenoside Rg3 (Rg3) 是红参的主要成分,通过抑制肿瘤细胞的粘附和侵袭来抑制肿瘤细胞肺转移。它抑制Na+和hKv1.4通道,IC50分别为 32.2±4.5 和 32.6±2.2 μM。它还抑制Aβ,NF-κB 活性和COX-2表达,抑制人脐静脉内皮细胞的增殖并具有抗血管生成活性。
TN1042 Chebulic acid

Others Others
Chebulic acid 是一种分离自Terminalia chebula 中的酚羧酸化合物,具有显著的抗氧化作用,它能够打破由晚期糖基化终产物 (AGEs) 诱导的蛋白质交联,阻碍 AGEs 的形成。它能够有效控制代谢参数升高、氧化应激和肾损害,支持其在糖尿病肾病中的有益作用。
T3860 Isoliquiritin apioside

MMP; p38 MAPK; NF-κB MAPK; NF-κB; Proteases/Proteasome
Isoliquiritin apioside 可抑制癌细胞和内皮细胞的侵袭和血管生成,显著降低 PMA 诱导的MMP9活性增加,并抑制 PMA 诱导的MAPK 和NF-κB 活化。
T5S2347 Deoxyshikonin

去氧紫草素,Arnebin 7

Others; HIF/HIF Prolyl-Hydroxylase; Antibacterial Chromatin/Epigenetic; Metabolism; Microbiology/Virology; Others
Deoxyshikonin (Arnebin 7) 是从紫草中分离的天然产物,具有抗肿瘤活性,在体外具有促血管生成作用。它和没食子酸十二烷基酯在体内外均与青霉素有显着的协同抗菌活性。
T5S1097 Neferine

(R)-1,2-Dimethoxyaporphine,(-)-Neferine,甲基莲心碱

Apoptosis; NF-κB; Autophagy Apoptosis; Autophagy; NF-κB
Neferine ((-)-Neferine) 是一种双苄基异喹啉类生物碱,可强效抑制NF-κB 激活,具有抗肿瘤活性。
T3923 Calycosin

Cyclosin,3'-Hydroxyformononetin,异黄酮,毛异黄酮

Apoptosis; Tyrosinase Apoptosis; Proteases/Proteasome
Calycosin (Cyclosin) 是一抗氧化和抗炎症活性天然产物。
T6S1966 Curculigoside

Curculigoside A,仙茅苷

Antioxidant; NF-κB; JAK; STAT Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; NF-κB; oxidation-reduction; Stem Cells
Curculigoside (Curculigoside A) 是仙茅中的主要皂苷,具有显著的抗氧化、抗骨质疏松、抗抑郁和神经保护作用。它通过调节JAK/STAT/NF-κB 信号传导途径,具有抗关节炎作用。
T6S0525 Farrerol

ERK; p38 MAPK; Akt Cytoskeletal Signaling; MAPK; PI3K/Akt/mTOR signaling
Farrerol 是一种杜鹃花的生物活性成分,具有抗氧化、抗肿瘤、抗炎、神经保护和肝保护等多种功能。
T4S2326 Cornuside

7-Galloylsecologanol,7-O-Galloylsecologanol,山茱萸新苷,Comuside

ERK; p38 MAPK; NF-κB; JNK MAPK; NF-κB
Cornuside (Comuside) 是从山茱萸的果实中分离出的环烯醚萜苷,可用于炎症疾病的研究和促进血液循环。 它通过下调 MAPK 和 NF-κB 信号通路抑制肥大细胞介导的过敏反应,用于炎性过敏性疾病中的潜能。
T5S2343 Acetylshikonin

乙酰紫草素,Acetyl shikonin

Others; P450; AChE Metabolism; Neuroscience; Others
Acetylshikonin 来源于紫草根,具有抗癌、抗炎作用。它是一种 AChE 抑制剂,具有很强的抗凋亡活性。它是一种非选择性的细胞色素 P450抑制剂,对所有 P450 亚型抑制的 IC50值范围为 1.4-4.0 μM。
T40942 (R)-(4′-Hydroxy)-5,7-dihydroxy-4-chromanone

Others Others
(R)-(4′-Hydroxy)-5,7-dihydroxy-4-chromanone, an antiangiogenic homoisoflavonoid, exhibits activity against human retinal microvascular endothelial cells.
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天然产物

Isolinderalactone
Cat.No: T8213
Synonym:
Target: NOS, STAT
Vaccarin
Cat.No: T3881
Synonym:
Target: Integrin, Akt, PERK, AMPK
Gamabufotalin
Cat.No: T4A2456
Synonym: Gamabufagin,日本蟾蜍毒苷元
Target: COX
Larixyl acetate
Cat.No: TN4417
Synonym:
Target: Others
(Z)-Guggulsterone
Cat.No: T17280
Synonym:
Target: Apoptosis, VEGFR, Akt
Tanshinone IIA
Cat.No: T2906
Synonym: 丹参酮IIA,Tanshinone B,Dan Shen ketone
Target: VEGFR
Xanthatin
Cat.No: T3S0153
Synonym: 苍耳亭,叶黄制菌素
Target: Apoptosis, VEGFR, Lipoxygenase, Wnt/beta-catenin, Antibacterial
Mollugin
Cat.No: T3673
Synonym: 大叶茜草素,Rubimaillin
Target: HER, JAK
Oglufanide
Cat.No: T7203
Synonym: 奥谷法奈,L-Glutamyl-L-tryptophan,H-Glu-Trp-OH
Target: VEGFR, HCV Protease, Endogenous Metabolite
Albendazole
Cat.No: T1152
Synonym: SKF-62979,阿苯达唑
Target: HIF/HIF Prolyl-Hydroxylase, Microtubule Associated, Antibiotic, Parasite
Pamufetinib
Cat.No: T13108
Synonym: H2OL3Q4XRD,4-(2-Fluoro-4-(3-(2-phenylacetyl)thioureido)phenoxy)-7-methoxy-N-methylquinoline-6-carboxamide,TAS-115
Target: VEGFR, c-Met/HGFR
Orobol
Cat.No: TN2019
Synonym: 3'-Hydroxygenistein,3’,4’,5,7-tetrahydroxy-isoflavon,3',4',5,7-四羟基异黄酮
Target: BCL, Caspase, PI3K
Chloramphenicol
Cat.No: T1205
Synonym: Chlornitromycin,Levomycetin,Chloromycetin,氯霉素
Target: ribosome, HIF/HIF Prolyl-Hydroxylase, Antibacterial, Antibiotic
Sodium taurocholate
Cat.No: TWA2417
Synonym: 牛黄胆酸钠(牛胆酸钠,牛胆酸钠盐,牛磺膽酸鈉,牛磺胆酸钠,牛磺胆酸钠盐,牛胆酸钠水合物,水合牛磺胆酸钠,牛胆酸钠(混合物),牛黄胆酸钠(水合),牛磺胆酸钠(标准品)),Taurocholate Sodium
Target: Others
5Z-7-Oxozeaenol
Cat.No: T14055
Synonym: FR148083,L783279,LL-Z 1640-2
Target: VEGFR, FLT, MEK, MAPK, PDGFR, Antibiotic, Src
5-Methoxy-DL-tryptophan
Cat.No: T5235
Synonym:
Target: Others, Endogenous Metabolite
N-Methylnicotinamide
Cat.No: T5233
Synonym: N'-Methylnicotinamide,Nicotinic Acid Methylamide,N-Methylpyridine-3-carboxamide,N-甲基烟酰胺
Target: Others, Endogenous Metabolite
Polydatin
Cat.No: T3427
Synonym: Piceid,虎杖苷,Polydotin Peceid
Target: Apoptosis, Mitophagy, NF-κB, Autophagy
2-Ethylpyrazine
Cat.No: T38248
Synonym:
Target: Endogenous Metabolite, NO Synthase
2-Methoxyestradiol
Cat.No: T2220
Synonym: 2-甲氧雌二醇,二甲氧基雌二醇,NSC-659853,2-MeOE2,2-ME2
Target: Apoptosis, Reactive Oxygen Species, Microtubule Associated, Endogenous Metabolite, HIF, Autophagy
Bacopaside II
Cat.No: TN1421
Synonym:
Target: Apoptosis
Medicarpin
Cat.No: TN1918
Synonym: 美迪紫檀素
Target: Apoptosis, BCL, ROS, JNK
Erianin
Cat.No: T3864
Synonym:
Target: BCL, Antibacterial
Casticin
Cat.No: T6S1373
Synonym: Quercetagetin 3,6,7,4'-Tetramethyl Ether,Vitexicarpin,蔓荆子黄素
Target: STAT
Thiolutin
Cat.No: T67708
Synonym: Acetopyrrothin
Target: Antibacterial, Antibiotic
(20S)-Protopanaxatriol
Cat.No: T2810
Synonym: 原人参三醇,20(S)-APPT,20 (S)-原人参三醇,g-PPT
Target: Apoptosis, Estrogen Receptor/ERR, Glucocorticoid Receptor, Estrogen/progestogen Receptor, Liver X Receptor
Tetrahydrobiopterin
Cat.No: T17056
Synonym: Sapropterin,BH4,(Rac)-Sapropterin
Target: NOS, Endogenous Metabolite
Bavachalcone
Cat.No: T3S0137
Synonym:
Target: Antibacterial, Antibiotic
Isorhamnetin
Cat.No: T2836
Synonym: 3-methylquercetin,3'-Methylquercetin,Isorhamnetol,异鼠李素,3'-Methoxyquercetin
Target: MEK, PI3K, Endogenous Metabolite
Terrestrosin D
Cat.No: T2S0886
Synonym:
Target: Apoptosis, Others
Tectoruside
Cat.No: TN6551
Synonym:
Target: Antioxidant
Artemitin
Cat.No: TCS1704
Synonym: 艾黄素,Artemetin,Artemisetin,Erianthin
Target: Antioxidant
Luteolinidin chloride
Cat.No: TN1895
Synonym:
Target: CD38
Rhamnose
Cat.No: T5120
Synonym: 6-Deoxyhexopyranose,L-鼠李糖,6-Deoxy-L-mannose,alpha-L-Rhamnose
Target: Calcium Channel, Endogenous Metabolite
Magnesium Lithospermate B
Cat.No: T20793
Synonym: 丹參酸B鎂,Monomethyl lithospermate B,丹参酸 B 镁,Lithospermate B
Target: Others
Tricetin
Cat.No: TN5171
Synonym:
Target: Apoptosis, Others, Nrf2
Ruscogenin
Cat.No: T6S1256
Synonym:
Target: NOS, NF-κB, NOD-like Receptor (NLR)
Norepinephrine
Cat.No: T7044
Synonym: 去甲肾上腺素,Levophed,Levonoradrenaline,Aktamin,Nor-Epirenan,Levonor,Arterenol
Target: MMP, Endogenous Metabolite, Adrenergic Receptor, Autophagy
Morroniside
Cat.No: T3414
Synonym: 莫诺苷,奎宁树
Target: Apoptosis, MMP, Pyroptosis
20(S)-Ginsenoside Rg3
Cat.No: T3402
Synonym: 20(S)-人参皂苷 Rg3,人参皂苷 Rg3,20(S)-Ginsenoside-Rg3,Rg3,20S-Ginsenoside Rg3,Ginsenoside Rg3,S-Ginsenoside Rg3
Target: EGFR, Beta Amyloid, Potassium Channel, NF-κB, COX, Sodium Channel, Endogenous Metabolite
Chebulic acid
Cat.No: TN1042
Synonym:
Target: Others
Isoliquiritin apioside
Cat.No: T3860
Synonym:
Target: MMP, p38 MAPK, NF-κB
Deoxyshikonin
Cat.No: T5S2347
Synonym: 去氧紫草素,Arnebin 7
Target: Others, HIF/HIF Prolyl-Hydroxylase, Antibacterial
Neferine
Cat.No: T5S1097
Synonym: (R)-1,2-Dimethoxyaporphine,(-)-Neferine,甲基莲心碱
Target: Apoptosis, NF-κB, Autophagy
Calycosin
Cat.No: T3923
Synonym: Cyclosin,3'-Hydroxyformononetin,异黄酮,毛异黄酮
Target: Apoptosis, Tyrosinase
Curculigoside
Cat.No: T6S1966
Synonym: Curculigoside A,仙茅苷
Target: Antioxidant, NF-κB, JAK, STAT
Farrerol
Cat.No: T6S0525
Synonym:
Target: ERK, p38 MAPK, Akt
Cornuside
Cat.No: T4S2326
Synonym: 7-Galloylsecologanol,7-O-Galloylsecologanol,山茱萸新苷,Comuside
Target: ERK, p38 MAPK, NF-κB, JNK
Acetylshikonin
Cat.No: T5S2343
Synonym: 乙酰紫草素,Acetyl shikonin
Target: Others, P450, AChE
(R)-(4′-Hydroxy)-5,7-dihydroxy-4-chromanone
Cat.No: T40942
Synonym:
Target: Others
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Cat. No. Product Name Species Expression System
TMPY-03156 VEGFC Protein, Mouse/Rat, Recombinant (aa 108-223, His)

vascular endothelial growth factor C

Mouse,Rat HEK293 Cells
VEGFC Protein, Mouse/Rat, Recombinant (aa 108-223, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.5 kDa and the accession number is P97953-1.
TMPY-03698 VEGF121b Protein, Human, Recombinant

MVCD1,VEGF,VPF,vascular endothelial growth factor A

Human HEK293 Cells
VEGF121b Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 34.10 kDa and the accession number is P15692-9.
TMPY-02432 VEGF164 Protein, Rat, Recombinant

血管内皮生长因子,vascular endothelial growth factor A

Rat Baculovirus Insect Cells
VEGF164 Protein, Rat, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 19.2 kDa and the accession number is P16612-2.
TMPY-04911 VEGF165 Protein, Human, Recombinant (His & Avi), Biotinylated

vascular endothelial growth factor A,血管内皮生长因子

Human,Cynomolgus HEK293 Cells
VEGF165 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 23.1 kDa and the accession number is P15692-4.
TMPY-00930 TIE2 Protein, Human, Recombinant (His & hFc)

VMCM1,TIE2,CD202B,TEK tyrosine kinase, endothelial,...

Human HEK293 Cells
TIE2 Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 108.5 kDa and the accession number is AAA61139.1.
TMPY-01064 TIE2 Protein, Human, Recombinant (His)

TIE2,VMCM,CD202B,TEK tyrosine kinase, endothelial,V...

Human HEK293 Cells
TIE2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 82 kDa and the accession number is AAA61139.1.
TMPY-01008 VEGFD Protein, Human, Recombinant (His)

VEGFD,c-fos induced growth factor (vascular endothelial<...

Human HEK293 Cells
VEGFD Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 13.6 kDa and the accession number is O43915.
TMPY-01717 VEGF164 Protein, Mouse, Recombinant

vascular endothelial growth factor A,Vpf,Vegf,血管内皮生...

Mouse Baculovirus Insect Cells
VEGF164 Protein, Mouse, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 19.4 kDa and the accession number is Q00731-2.
TMPJ-00864 VEGF165 Protein, Human, Recombinant

Vascular Endothelial Growth Factor Isoform 165,血管内皮...

Human HEK293 Cells
Human Vascular endothelial growth factor (VEGF), also known as VEGF-A and vascular permeability factor (VPF), belongs to the platelet-derived growth factor family of cysteine-knot growth factors. It is a potent activator in vasculogenesis and angiogenesis both physiologically and pathologically. VEGF-A has 8 differently spliced isoforms, of which VEGF165 is the most abundant one. VEGF165 is a disulfide-linked homodimer consisting of two glycosylated 165 amino acid polypeptide chains. VEGF stimul...
TMPY-00970 CD31/PECAM-1 Protein, Human, Recombinant (His)

platelet/endothelial cell adhesion molecule 1,GPIIA...

Human HEK293 Cells
CD31/PECAM-1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 66 kDa and the accession number is EAW94208.1.
TMPY-01007 VEGFC Protein, Human, Recombinant (His)

血管内皮生长因子,LMPH1D,VEGF-C,Flt4-L,vascular endothelial ...

Human HEK293 Cells
VEGFC Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.5 kDa and the accession number is P49767.
TMPJ-00865 VEGF121 Protein, Human, Recombinant (His)

VEGFA,VEGF-A,Vascular permeability factor,VPF,血管内皮生长因子,Vascu...

Human HEK293 Cells
Human VEGF121, also known as Vascular endothelial growth factor A, VEGFA, Vascular permeability factor, VPF and VEGF, is a homodimeric, heparin-binding glycoprotein which belongs to the platelet-derived growth factor (PDGF)/vascular endothelial growth factor (VEGF) family. VEGF-A is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis, permeabilization of blood vessel...
TMPJ-00603 TL1A/TNFSF15 Protein, Mouse, Recombinant

TNFSF15,Tumor Necrosis Factor Ligand Superfamily Member 15,V...

Mouse E. coli
Tumor Necrosis Factor Ligand Superfamily Member 15 (TNFSF15) is a new member of the tumor necrosis factor family. TNFSF15 is predominantly an endothelial cell-specific gene, and recombinant TNFSF15 is a potent inhibitor of endothelial cell proliferation, angiogenesis and tumor growth. TNFSF15 exerts two activities on endothelial cells: early G1 arrest of G0/G1-cells responding to growth stimuli and programmed cell death of proliferating cells. These activities are highly specific to endothelial ...
TMPY-02745 ESAM Protein, Rat, Recombinant (hFc)

endothelial cell adhesion molecule

Rat HEK293 Cells
ESAM Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 51.2 kDa and the accession number is Q6AYD4.
TMPY-02508 TIE2 Protein, Rat, Recombinant (hFc)

TEK tyrosine kinase, endothelial

Rat HEK293 Cells
TIE2 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 108 kDa and the accession number is A6JRG8.
TMPY-03347 EPCR Protein, Rat, Recombinant (His)

protein C receptor, endothelial

Rat HEK293 Cells
EPCR Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 23.2 kDa.
TMPY-05049 TIE2 Protein, Rhesus, Recombinant (His)

TEK tyrosine kinase, endothelial

Rhesus HEK293 Cells
TIE2 Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 84.2 kDa and the accession number is G7NFP9.
TMPY-03832 EPCR Protein, Cynomolgus, Recombinant (hFc)

protein C receptor, endothelial

Cynomolgus HEK293 Cells
EPCR Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 48.9 kDa and the accession number is XP_001100647.1.
TMPY-03563 TIE2 Protein, Cynomolgus, Recombinant (hFc)

TEK tyrosine kinase, endothelial

Cynomolgus HEK293 Cells
TIE2 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 107.6 kDa and the accession number is G7PS68.
TMPY-03594 EPCR Protein, Cynomolgus, Recombinant (His)

protein C receptor, endothelial

Cynomolgus HEK293 Cells
EPCR Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 23.3 kDa.
TMPY-00798 ESAM Protein, Human, Recombinant

endothelial cell adhesion molecule,W117m

Human HEK293 Cells
ESAM Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 24.5 kDa and the accession number is Q96AP7-1.
TMPY-01312 ESAM Protein, Human, Recombinant (His)

endothelial cell adhesion molecule,W117m

Human HEK293 Cells
ESAM Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.4 kDa and the accession number is Q96AP7-1.
TMPY-00797 ESAM Protein, Human, Recombinant (hFc)

W117m,endothelial cell adhesion molecule

Human HEK293 Cells
ESAM Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 50.5 kDa and the accession number is Q96AP7-1.
TMPJ-00412 VEGFR1/FLT-1 Protein, Human, Recombinant (hFc)

Vascular endothelial growth factor receptor 1,Vascu...

Human HEK293 Cells
Human Vascular endothelial growth factor receptor 1(VEGFR-1, FLT-1) is a member of the the class III subfamily of receptor tyrosine kinases (RTKs) and Tyr protein kinase family and CSF-1/PDGF receptor subfamily. VEGFR-1 is widely expressed in human tissues including normal lung, placenta, liver, kidney, heart and brain tissues. It is specifically expressed in most of the vascular endothelial cellsand peripheral blood monocytes. VEGFR-1 contains seven Ig-like C2-type domains and one protein kinas...
TMPY-00624 PEAR1 Protein, Rat, Recombinant (His)

platelet endothelial aggregation receptor 1

Rat Baculovirus Insect Cells
Platelet endothelial aggregation receptor-1 (PEAR1), an epidermal growth factor repeat-containing transmembrane receptor, is known to participate in platelet contact-induced activation. Platelet endothelial aggregation receptor 1 (PEAR1) triggers platelet aggregation and is expressed in platelets and endothelial cells.PEAR1 encodes the Platelet-Endothelial Aggregation Receptor 1, a contact receptor involved in platelet function and megakaryocyte and endothelial cell proliferation. PEAR1 expressi...
TMPY-03155 VEGFC Protein, Mouse/Rat, Recombinant (aa 108-223, hFc)

vascular endothelial growth factor C

Mouse,Rat HEK293 Cells
VEGFC Protein, Mouse/Rat, Recombinant (aa 108-223, hFc) is expressed in HEK293 mammalian cells with Fc tag. The predicted molecular weight is 41.5 kDa and the accession number is O35757.
TMPY-03887 ESM1 Protein, Human, Recombinant (His)

endothelial cell-specific molecule 1,endocan

Human Baculovirus Insect Cells
ESM1 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 19.6 kDa and the accession number is Q9NQ30-1.
TMPY-03192 EPCR Protein, Human, Recombinant (hFc)

CCCA,protein C receptor, endothelial,CCD41,EPCR

Human HEK293 Cells
EPCR Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 48.9 kDa and the accession number is AAH14451.1.
TMPY-02734 ESAM Protein, Mouse, Recombinant (His)

endothelial cell adhesion molecule,2310008D05Rik,W1...

Mouse HEK293 Cells
ESAM Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.6 kDa and the accession number is Q925F2.
TMPY-02715 EPCR Protein, Human, Recombinant (His)

EPCR,CCD41,CCCA,protein C receptor, endothelial

Human HEK293 Cells
EPCR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 23.4 kDa and the accession number is Q9UNN8.
TMPY-02487 EPCR Protein, Mouse, Recombinant (His)

Ccd41,Ccca,AI325044,protein C receptor, endothelial...

Mouse HEK293 Cells
EPCR Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 23.7 kDa and the accession number is Q64695.
TMPY-02489 EPCR Protein, Mouse, Recombinant (hFc)

Ccd41,Ccca,Epcr,AI325044,protein C receptor, endothelial...

Mouse HEK293 Cells
EPCR Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.3 kDa and the accession number is Q64695.
TMPY-03230 ESM1 Protein, Mouse, Recombinant (His)

0610042H23Rik,ESM-1,endothelial cell-specific molec...

Mouse Baculovirus Insect Cells
ESM1 Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 19.17 kDa and the accession number is Q9QYY7.
TMPY-03080 VEGF165 Protein, Danio rerio (zebrafish), Recombinant

血管内皮生长因子,vascular endothelial growth factor A

Danio rerio (zebrafish) Baculovirus Insect Cells
VEGF165 Protein, Danio rerio (zebrafish), Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 19.2 kDa and the accession number is O73682.
TMPH-02513 TEM8/ANTXR1 Protein, Mouse, Recombinant (His & Myc)

Antxr1,Tumor endothelial marker 8,Anthrax toxin rec...

Mouse HEK293 Cells
Plays a role in cell attachment and migration. Interacts with extracellular matrix proteins and with the actin cytoskeleton. Mediates adhesion of cells to type 1 collagen and gelatin, reorganization of the actin cytoskeleton and promotes cell spreading. Plays a role in the angiogenic response of cultured umbilical vein endothelial cells.
TMPY-03705 VEGF164 Protein, Canine, Recombinant

血管内皮生长因子,vascular endothelial growth factor A

Canine HEK293 Cells
VEGF164 Protein, Canine, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 17 kDa and the accession number is Q9MYV3-3.
TMPY-04545 TIE2 Protein, Human, Recombinant (His & GST)

VMCM,CD202B,TIE-2,VMCM1,TEK tyrosine kinase, endothelial...

Human Baculovirus Insect Cells
TIE2 Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 68.3 kDa and the accession number is Q02763-1.
TMPY-03200 VEGFD Protein, Rat, Recombinant (hFc)

c-fos induced growth factor (vascular endothelial g...

Rat HEK293 Cells
VEGFD Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 41.6 kDa and the accession number is O35251.
TMPH-02837 PLXDC1 Protein, Mouse, Recombinant (His)

Tumor endothelial marker 7,Plexin domain-containing...

Mouse P. pastoris (Yeast)
Plays a critical role in endothelial cell capillary morphogenesis.
TMPH-02836 PLXDC1 Protein, Mouse, Recombinant (E. coli, His)

Plexin domain-containing protein 1,Plxdc1,Tumor endothel...

Mouse E. coli
Plays a critical role in endothelial cell capillary morphogenesis. PLXDC1 Protein, Mouse, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 49.3 kDa and the accession number is Q91ZV7.
TMPH-02512 TEM8/ANTXR1 Protein, Mouse, Recombinant (His)

Tumor endothelial marker 8,Anthrax toxin receptor 1...

Mouse E. coli
Plays a role in cell attachment and migration. Interacts with extracellular matrix proteins and with the actin cytoskeleton. Mediates adhesion of cells to type 1 collagen and gelatin, reorganization of the actin cytoskeleton and promotes cell spreading. Plays a role in the angiogenic response of cultured umbilical vein endothelial cells.
TMPH-01113 COL8A1 Protein, Human, Recombinant (His & SUMO)

Endothelial collagen,C3orf7,COL8A1,Collagen alpha-1...

Human E. coli
COL8A1 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli.
TMPH-03131 VEGFA Protein, Pig, Recombinant (His)

Vascular endothelial growth factor A,VEGFA,Vascular...

Sus scrofa (Pig) E. coli
VEGFA Protein, Pig, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 23.2 kDa and the accession number is P49151.
TMPY-05244 TIE2 Protein, Human, Recombinant (His), Biotinylated

TIE2,TEK tyrosine kinase, endothelial,CD202B,VMCM,V...

Human HEK293 Cells
TIE2 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 82 kDa and the accession number is AAA61139.1.
TMPY-04327 VEGFB Protein, Human, Recombinant (hFc)

VRF,血管内皮生长因子,vascular endothelial growth factor B,V...

Human HEK293 Cells
Vascular endothelial growth factor-B (VEGF-B) is closely related to VEGF-A, an effector of blood vessel growth during development and disease and a strong candidate for angiogenic therapies. In detail, VEGFB can positively prevent the Ang II-induced rising in the size of cardiomyocyte as well as reduce Ang II-induced mRNA and protein levels of β-MHC (β-myosin heavy chain), BNP (brain natriuretic peptide), and ANP (atrial natriuretic peptide). Moreover, VEGFB can regulate the decline of the Ang I...
TMPY-04575 TIE2 Protein, Mouse, Recombinant (aa 770-1122, His & GST)

Cd202b,AA517024,STK1,Tie2,Tie-2,TEK tyrosine kinase, end...

Mouse Baculovirus Insect Cells
TIE2 Protein, Mouse, Recombinant (aa 770-1122, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 68.2kDa and the accession number is Q02858.
TMPY-01954 TIE2 Protein, Mouse, Recombinant (hFc)

Tie-2,STK1,Tie2,Hyk,Cd202b,AA517024,TEK tyrosine kinase,

Mouse HEK293 Cells
TIE2 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 107.7 kDa and the accession number is B1AWS8.
TMPY-06974 TIE2 Protein, Mouse, Recombinant (His), Biotinylated

AA517024,Tie2,STK1,Hyk,Tie-2,TEK tyrosine kinase, endoth...

Mouse HEK293 Cells
TIE2 Protein, Mouse, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 82.03 kDa and the accession number is Q02858.
TMPJ-01333 TEM8/ANTXR1 Protein, Human, Recombinant (His)

ATR,ANTXR1,TEM8,Tumor Endothelial Marker 8,Anthrax ...

Human HEK293 Cells
Anthrax Toxin Receptor 1 (ANTXR1) is a single-pass type I membrane protein that belongs to the ATR family. ANTXR1 contains one VWFA domain and binds PA through the VWA domain. ANTXR1 is highly expressed in tumor endothelial cells. ANTXR1 plays a role in cell attachment and migration. ANTXR1 interacts with extracellular matrix proteins and the actin cytoskeleton, it mediates adhesion of cells to type 1 collagen and gelatin, reorganization of the actin cytoskeleton and promotes cell spreading. It ...
TMPY-01619 CD31/PECAM-1 Protein, Mouse, Recombinant (His)

Pecam,C85791,PECAM-1,Cd31,platelet/endothelial cell...

Mouse HEK293 Cells
CD31/PECAM-1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 66 kDa and the accession number is Q03311.
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重组蛋白

VEGFC Protein, Mouse/Rat, Recombinant (aa 108-223, His)
Cat.No: TMPY-03156
Species: Mouse,Rat
Expression System: HEK293 Cells
VEGF121b Protein, Human, Recombinant
Cat.No: TMPY-03698
Species: Human
Expression System: HEK293 Cells
VEGF164 Protein, Rat, Recombinant
Cat.No: TMPY-02432
Species: Rat
Expression System: Baculovirus Insect Cells
VEGF165 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-04911
Species: Human,Cynomolgus
Expression System: HEK293 Cells
TIE2 Protein, Human, Recombinant (His & hFc)
Cat.No: TMPY-00930
Species: Human
Expression System: HEK293 Cells
TIE2 Protein, Human, Recombinant (His)
Cat.No: TMPY-01064
Species: Human
Expression System: HEK293 Cells
VEGFD Protein, Human, Recombinant (His)
Cat.No: TMPY-01008
Species: Human
Expression System: HEK293 Cells
VEGF164 Protein, Mouse, Recombinant
Cat.No: TMPY-01717
Species: Mouse
Expression System: Baculovirus Insect Cells
VEGF165 Protein, Human, Recombinant
Cat.No: TMPJ-00864
Species: Human
Expression System: HEK293 Cells
CD31/PECAM-1 Protein, Human, Recombinant (His)
Cat.No: TMPY-00970
Species: Human
Expression System: HEK293 Cells
VEGFC Protein, Human, Recombinant (His)
Cat.No: TMPY-01007
Species: Human
Expression System: HEK293 Cells
VEGF121 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00865
Species: Human
Expression System: HEK293 Cells
TL1A/TNFSF15 Protein, Mouse, Recombinant
Cat.No: TMPJ-00603
Species: Mouse
Expression System: E. coli
ESAM Protein, Rat, Recombinant (hFc)
Cat.No: TMPY-02745
Species: Rat
Expression System: HEK293 Cells
TIE2 Protein, Rat, Recombinant (hFc)
Cat.No: TMPY-02508
Species: Rat
Expression System: HEK293 Cells
EPCR Protein, Rat, Recombinant (His)
Cat.No: TMPY-03347
Species: Rat
Expression System: HEK293 Cells
TIE2 Protein, Rhesus, Recombinant (His)
Cat.No: TMPY-05049
Species: Rhesus
Expression System: HEK293 Cells
EPCR Protein, Cynomolgus, Recombinant (hFc)
Cat.No: TMPY-03832
Species: Cynomolgus
Expression System: HEK293 Cells
TIE2 Protein, Cynomolgus, Recombinant (hFc)
Cat.No: TMPY-03563
Species: Cynomolgus
Expression System: HEK293 Cells
EPCR Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPY-03594
Species: Cynomolgus
Expression System: HEK293 Cells
ESAM Protein, Human, Recombinant
Cat.No: TMPY-00798
Species: Human
Expression System: HEK293 Cells
ESAM Protein, Human, Recombinant (His)
Cat.No: TMPY-01312
Species: Human
Expression System: HEK293 Cells
ESAM Protein, Human, Recombinant (hFc)
Cat.No: TMPY-00797
Species: Human
Expression System: HEK293 Cells
VEGFR1/FLT-1 Protein, Human, Recombinant (hFc)
Cat.No: TMPJ-00412
Species: Human
Expression System: HEK293 Cells
PEAR1 Protein, Rat, Recombinant (His)
Cat.No: TMPY-00624
Species: Rat
Expression System: Baculovirus Insect Cells
VEGFC Protein, Mouse/Rat, Recombinant (aa 108-223, hFc)
Cat.No: TMPY-03155
Species: Mouse,Rat
Expression System: HEK293 Cells
ESM1 Protein, Human, Recombinant (His)
Cat.No: TMPY-03887
Species: Human
Expression System: Baculovirus Insect Cells
EPCR Protein, Human, Recombinant (hFc)
Cat.No: TMPY-03192
Species: Human
Expression System: HEK293 Cells
ESAM Protein, Mouse, Recombinant (His)
Cat.No: TMPY-02734
Species: Mouse
Expression System: HEK293 Cells
EPCR Protein, Human, Recombinant (His)
Cat.No: TMPY-02715
Species: Human
Expression System: HEK293 Cells
EPCR Protein, Mouse, Recombinant (His)
Cat.No: TMPY-02487
Species: Mouse
Expression System: HEK293 Cells
EPCR Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-02489
Species: Mouse
Expression System: HEK293 Cells
ESM1 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-03230
Species: Mouse
Expression System: Baculovirus Insect Cells
VEGF165 Protein, Danio rerio (zebrafish), Recombinant
Cat.No: TMPY-03080
Species: Danio rerio (zebrafish)
Expression System: Baculovirus Insect Cells
TEM8/ANTXR1 Protein, Mouse, Recombinant (His & Myc)
Cat.No: TMPH-02513
Species: Mouse
Expression System: HEK293 Cells
VEGF164 Protein, Canine, Recombinant
Cat.No: TMPY-03705
Species: Canine
Expression System: HEK293 Cells
TIE2 Protein, Human, Recombinant (His & GST)
Cat.No: TMPY-04545
Species: Human
Expression System: Baculovirus Insect Cells
VEGFD Protein, Rat, Recombinant (hFc)
Cat.No: TMPY-03200
Species: Rat
Expression System: HEK293 Cells
PLXDC1 Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02837
Species: Mouse
Expression System: P. pastoris (Yeast)
PLXDC1 Protein, Mouse, Recombinant (E. coli, His)
Cat.No: TMPH-02836
Species: Mouse
Expression System: E. coli
TEM8/ANTXR1 Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02512
Species: Mouse
Expression System: E. coli
COL8A1 Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-01113
Species: Human
Expression System: E. coli
VEGFA Protein, Pig, Recombinant (His)
Cat.No: TMPH-03131
Species: Sus scrofa (Pig)
Expression System: E. coli
TIE2 Protein, Human, Recombinant (His), Biotinylated
Cat.No: TMPY-05244
Species: Human
Expression System: HEK293 Cells
VEGFB Protein, Human, Recombinant (hFc)
Cat.No: TMPY-04327
Species: Human
Expression System: HEK293 Cells
TIE2 Protein, Mouse, Recombinant (aa 770-1122, His & GST)
Cat.No: TMPY-04575
Species: Mouse
Expression System: Baculovirus Insect Cells
TIE2 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-01954
Species: Mouse
Expression System: HEK293 Cells
TIE2 Protein, Mouse, Recombinant (His), Biotinylated
Cat.No: TMPY-06974
Species: Mouse
Expression System: HEK293 Cells
TEM8/ANTXR1 Protein, Human, Recombinant (His)
Cat.No: TMPJ-01333
Species: Human
Expression System: HEK293 Cells
CD31/PECAM-1 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01619
Species: Mouse
Expression System: HEK293 Cells
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Cat. No. Product Name Target Signaling Pathways
TMIH-0124 Brivanib Alaninate-d4

Brivanib Alaninate-d4 是 Brivanib Alaninate 的氘代化合物。Brivanib Alaninate 的 CAS 号为 649735-63-7。Brivanib alaninate 是一种血管内皮生长因子受体 2 (VEGFR2) 抑制剂的丙氨酸盐,IC50值为 25 nM,具有潜在的抗肿瘤活性。它对 VEGFR1 和 FGFR1 适度抑制,对 VEGFR2 的选择性是对 PDGFRβ 的 240 倍。
TMID-0021 Fruquintinib-d3

Fruquintinib-d3 是 Fruquintinib 的氘代化合物。Fruquintinib 的 CAS 号为 1194506-26-7。Fruquintinib 是一种选择性的VEGFR 1/2/3抑制剂,它们的IC50值分别为33 nM、0.5 nM、35 nM。
T70990 ADMA-d6

NG,NG-dimethyl-L-arginine-d6 (ADMA-d6) (hydrochloride) is intended for use as an internal standard for the quantification of NG,NG-dimethyl-L-arginine by GC- or LC-MS. ADMA is an endogenous inhibitor of nitric oxide synthase (NOS). It is formed from arginine by protein arginine methyltransferases (PRMTs) and degraded by dimethylarginine dimethylaminohydrolases (DDAHs) and alanine-glyoxylate aminotransferase 2 (AGXT2). ADMA levels are increased concomitant with an increase in blood pressure in Da...
T35775 HT-2 Toxin-13C22

HT-2 Toxin-13C22

HT-2 toxin-13C22is intended for use as an internal standard for the quantification of HT-2 toxin by GC- or LC-MS. HT-2 toxin is a type A trichothecene mycotoxin and an active, deacetylated metabolite of the trichothecene mycotoxin T-2 toxin .1,2Like T-2 toxin, HT-2 toxin inhibits protein synthesis and cell proliferation in plants.2HT-2 toxin also reduces viability of HepG2, A549, HEp-2, Caco-2, A-204, U937, Jurkat, and RPMI-8226 cancer cells with IC50values ranging from 3.1 to 23 ng/ml and human...
TMIJ-0114 Vardenafil-d5

Vardenafil-d5 是 Vardenafil 的氘代化合物。Vardenafil 的 CAS 号为 224785-90-4。Vardenafil 是选择性、高效的、具有口服活性的磷酸二酯酶5抑制剂,IC50=0.7 nM。它能够非竞争性地抑制环磷酸鸟苷水解,从而提高 cGMP 水平。它对 PDE1 (180 nM),PDE6 (11 nM),PDE2,PDE3,PDE4 (>1000 nM) 具有选择性。它可用于研究勃起功能障碍。
T35789 Palmitic acid-1-13C

Palmitic acid-13C is intended for use as an internal standard for the quantification of palmitic acid by GC- or LC-MS. Palmitic acid is a 16-carbon saturated fatty acid. It comprises approximately 25% of human total plasma lipids.1 It increases protein levels of COX-2 in RAW 264.7 cells when used at a concentration of 75 μM.2 Palmitic acid is involved in the acylation of proteins to anchor membrane-bound proteins to the lipid bilayer.2,3,4,5,6 |1. Santos, M.J., López-Jurado, M., Llopis, J., et a...
T35791 Palmitic acid-13C

Palmitic acid-13C is intended for use as an internal standard for the quantification of palmitic acid by GC- or LC-MS. Palmitic acid-13C contains 13C at the C2 position and has been used in the study of free fatty acid incorporation into phospholipid fatty acids in soil microbes.1 Palmitic acid is a 16-carbon saturated fatty acid. It comprises approximately 25% of human total plasma lipids.2 It increases protein levels of COX-2 in RAW 264.7 cells when used at a concentration of 75 μM.3 Palmitic ...

同位素标记化合物

Brivanib Alaninate-d4
Cat.No: TMIH-0124
Synonym:
Target:
Fruquintinib-d3
Cat.No: TMID-0021
Synonym:
Target:
ADMA-d6
Cat.No: T70990
Synonym:
Target:
HT-2 Toxin-13C22
Cat.No: T35775
Synonym: HT-2 Toxin-13C22
Target:
Vardenafil-d5
Cat.No: TMIJ-0114
Synonym:
Target:
Palmitic acid-1-13C
Cat.No: T35789
Synonym:
Target:
Palmitic acid-13C
Cat.No: T35791
Synonym:
Target:
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