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Nω-Propyl-L-arginine, a powerful and specific inhibitor of neuronal nitric oxide synthase (nNOS), effectively inhibits nNOS with a Ki of 57 nM. It exhibits a remarkable 149-fold selectivity for nNOS over endothelial NOS (eNOS).
Nω-Propyl-L-arginine, a powerful and specific inhibitor of neuronal nitric oxide synthase (nNOS), effectively inhibits nNOS with a Ki of 57 nM. It exhibits a remarkable 149-fold selectivity for nNOS over endothelial NOS (eNOS).
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
5 mg | ¥ 962 | 35日内发货 | |
10 mg | ¥ 1,760 | 35日内发货 | |
50 mg | ¥ 7,350 | 35日内发货 | |
100 mg | ¥ 12,800 | 35日内发货 |
产品描述 | Nω-Propyl-L-arginine, a powerful and specific inhibitor of neuronal nitric oxide synthase (nNOS), effectively inhibits nNOS with a Ki of 57 nM. It exhibits a remarkable 149-fold selectivity for nNOS over endothelial NOS (eNOS). |
体内活性 | Nω-Propyl-L-arginine (N-omega-Propyl-L-arginine) (20 mg/kg; i.p.) blocks both phencyclidine-induced disruption of prepulse inhibition and phencyclidine-induced stimulation of locomotor activity[2]. Animal Model: Male NMRI mice (30-40 g) (phencyclidine-induced stimulation)[2]Dosage: 20 mg/kg Administration: I.p. Result: Markedly reduced the phencyclidineinduced disruption of prepulse inhibition and significantly reduced the phencyclidine-induced stimulation of locomotor activity. |
别名 | Nω-Propyl-L-arginine, N-omega-Propyl-L-arginine |
分子量 | 216.28 |
分子式 | C9H20N4O2 |
CAS No. | 137361-05-8 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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