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Search Results for " type-2 "

Targets Recommended: Others

508

抑制剂 & 化合物

85

天然产物

5

化合物库

3

TargetMol 试剂盒

673

重组蛋白

14

同位素标记化合物

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Cat. No.	Product Name
L9700	内质网应激化合物库		193 compounds
	193 个内质网应激相关的化合物集合，可用于高通量和高内涵筛选；
L2191	抗乳腺癌化合物库		1939 compounds
	1939 种与乳腺癌相关的化合物，可以用于抗乳腺癌药物研发和药理研究；
L2540	肠道微生物代谢化合物库		614 compounds
	614 种肠道微生物代谢物的集合，可以用于高通量和高内涵筛选；
L1120	AMPK靶向分子库		80 compounds
	80 个靶向AMPK 的分子集合，可用于高通量和高内涵筛选；
L2550	谷氨酰胺代谢化合物库		565 compounds
	565 种谷氨酰胺代谢相关的分子，可以用于高通量和高内涵筛选；

化合物库

内质网应激化合物库

Cat.No: L9700

Compounds: 193

抗乳腺癌化合物库

Cat.No: L2191

Compounds: 1939

肠道微生物代谢化合物库

Cat.No: L2540

Compounds: 614

AMPK靶向分子库

Cat.No: L1120

Compounds: 80

谷氨酰胺代谢化合物库

Cat.No: L2550

Compounds: 565

Cat. No.	Product Name	Form	Specificity Of Inhibition
C0109	Magrose Beads IDA-Nickel His-tag 蛋白纯化磁珠 IDA-Ni	Suspension in bottle	蛋白纯化
C0110	Magrose Beads IDA-Cobalt His-tag 蛋白纯化磁珠 IDA-Co	Suspension in bottle	蛋白纯化
C0111	Magrose Beads NTA-Nickel (Ultra-suspension) His-tag 蛋白纯化磁珠 NTA-Ni	Suspension in bottle	蛋白纯化

TargetMol 试剂盒

His-tag 蛋白纯化磁珠 IDA-Ni

Cat.No: C0109

His-tag 蛋白纯化磁珠 IDA-Co

Cat.No: C0110

His-tag 蛋白纯化磁珠 NTA-Ni

Cat.No: C0111

Cat. No.	Product Name	Target	Signaling Pathways
T39392L	C-Type Natriuretic Peptide (1-22) acetate（human） C-Type Natriuretic Peptide (CNP) (1-22), human acetate(1966153-17-2 Free base)	Others	Others
	C-Type Natriuretic Peptide (CNP) (1-22), human acetate 是一种利钠肽受体 B (NPR-B) 的激动剂，一种内皮衍生的松弛剂和生长抑制因子。 C-Type Natriuretic Peptide (CNP) (1-22), human acetate 抑制由组胺和 5-HT 或直接由毛喉素刺激的 cAMP 合成。
T13867	RH01386	Others	Others
	RH01386是可以预防 ER 应激诱导的β细胞功能障碍和死亡、抑制促凋亡基因表达的小分子。它恢复内质网应激受损的葡萄糖刺激的胰岛素分泌反应。对2型糖尿病具有潜在的研究价值。
T9022	AZD9977 AZD 9977	Glucocorticoid Receptor	Endocrinology/Hormones
	AZD9977 是一种选择性的，有效的，具有口服活性的盐皮质激素受体 (MR) 调节剂，可用于研究心力衰竭和慢性肾病。
T15159	Dorzagliatin HMS5552	Glucokinase	Metabolism
	Dorzagliatin (HMS5552) 是双重作用的葡萄糖激酶 (glucokinase;GK) 激活剂，可改善 2 型糖尿病的血糖控制，提高胰腺 β 细胞功能。
T15432	GSK256073	GPR; Others	Endocrinology/Hormones; GPCR/G Protein; Others
	GSK256073 是一种口服有活性的GPR109A 选择性激动剂，也是一种持久的人HCA2激动剂(pEC50:7.5) 。它能够减少脂降解，而显著改善葡萄糖稳态，对 2 型糖尿病和血脂异常具有潜在的研究价值。
T14315	AR-9281 APAU	Epoxide Hydrolase	Metabolism
	AR-9281 (APAU) 是选择性的可溶性环氧化物水解酶抑制剂，可用于研究高血压和 2 型糖尿病。
T3978	Linerixibat GSK2330672,Iinerixibat	HBV	Microbiology/Virology
	Linerixibat (GSK2330672) 是高效的、不可吸收的、具有口服活性的顶端钠依赖性胆汁酸转运蛋白 (ASBT) 抑制剂，对人ASBT 的IC50为 42 nM。它是一种降脂剂，具有用于 2 型糖尿病和原发性胆源性胆管炎的研究潜力。
T8944	TTA-A2	Calcium Channel	Membrane transporter/Ion channel; Metabolism
	TTA-A2 是一种选择性 T 型钙通道拮抗剂，是一种有效的抗惊厥药，可减少孕烷 X 受体的激活。它对 Cav3.1 (a1G) 和 Cav3.2 (a1H) 通道在 -80 mV 和- 100 mV 保持电位上具有同样的作用，IC50 值分别为 89 和 92 nM。它可用于多种人类神经系统疾病的研究，包括睡眠障碍和癫痫。
T16074	Mifobate SR-202,米福贝特	PPAR	DNA Damage/DNA Repair; Metabolism
	Mifobate (SR-202) 是一种有效且特异性的 PPARγ拮抗剂，可选择性抑制噻唑烷二酮 (TZD) 诱导的 PPARγ 转录活性，IC50为140 μM，具有抗肥胖和抗糖尿病作用。
T1088	Repaglinide AG-EE 388 ZW,AG-EE 623ZW,瑞格列奈	Potassium Channel; PPAR	DNA Damage/DNA Repair; Membrane transporter/Ion channel; Metabolism
	Repaglinide (AG-EE 623ZW) 是一种能够用于2 型糖尿病的胰岛素促分泌剂。
T21900	ML-336 (E)-2-((1,4-二甲基哌嗪-2-亚基)氨基)-5-硝基-N-苯基苯甲酰胺	Others	Others
	ML-336 是一种喹唑啉酮类的委内瑞拉马脑炎病毒 (VEEV) 抑制剂，其VEEV TC-83 CPE(IC50:32 nM)、VEEV V3526 CPE(IC50:20 nM)、VEEV 野生型 CPE (IC50:42 nM)，有效抑制 VEEV 诱导的三种病毒株 (V3526、TC-83和野生型) 细胞病变效应。
T12302	OMDM-1 (Z)-N-[(2S)-1-hydroxy-3-(4-hydroxyphenyl)propan-2-yl]octadec-9-enamide	Endogenous Metabolite	Metabolism
	OMDM-1 ((Z)-N-[(2S)-1-hydroxy-3-(4-hydroxyphenyl)propan-2-yl]octadec-9-enamide) 是有效选择性的代谢稳定 anandamide 细胞摄取抑制剂，Ki=为2.4 μM。
T1603	Glipizide CP 28720,K 4024,格列吡嗪	Potassium Channel; PPAR; ABC	DNA Damage/DNA Repair; Membrane transporter/Ion channel; Metabolism
	Glipizide (CP 28720) 是一种有效的、具有口服活性的磺酰脲类抗糖尿病试剂 (anti-diabetic agent)，在 2 型糖尿病的研究中具有价值，但不适用于1 型糖尿病。Glipizide 是通过部分阻断郎格汉斯胰岛细胞中 ATP 敏感钾通道 (KATP)发挥活性。
T3184	Kevetrin hydrochloride Thioureidobutyronitrile HCl,thioureido butyronitrile hydrochloride,4-Isothioureidobutyronitrile hydrochloride	Mdm2; p53	Apoptosis
	Kevetrin hydrochloride (4-Isothioureidobutyronitrile hydrochloride) 是一种小分子，是肿瘤抑制蛋白 p53 的激活剂，具有潜在的抗肿瘤活性。
T64203	T-Type calcium channel inhibitor 2	Others	Others
	T-Type calcium channel inhibitor 2 (compound 6g) 是一种 T 型钙通道的有效抑制剂，能够作用于 Cav3.1 (α1G) (IC50: 31.0 μM)、Cav3.2 (α1H) (IC50: 83.1 μM)、Cav3.3 (α1I) (α1H) (IC50: 69.3 μM)。T-Type calcium channel inhibitor 2 对 A549、HCT-116 细胞表现出细胞毒性，IC50s 分别为5.0、6.4 μM。
T63893	Adenylyl cyclase type 2 agonist-1	Others	Others
	Adenylyl cyclase type 2 agonist-1 是腺苷酸环化酶 2 型 (AC2) 有效的激动剂 (EC50: 90 nM)。Adenylyl cyclase type 2 agonist-1 能够抑制 Interleukin-6 的表达，是一种潜在的对抗呼吸系统疾病的先导化合物。
T22276	Bis(maltolato)oxovanadium(IV) 双(麦芽醇)氧钒(IV),BMOV,Bis maltolato oxovanadium,Bis(maltolato)oxovanadium (IV),bis maltolato oxo vanadium,Bis(maltolato)oxovanadium (IV)	Phosphatase; Others	Metabolism; Others
	Bis(maltolato)oxovanadium(IV) (BMOV) 是一种有效的胰岛素增敏剂，也是一种有效的、竞争性的、可逆的、口服具有活性的光谱蛋白酪氨酸磷酸酶 (PTP) 抑制剂。它抑制HCPTPA，PTP1B，HPTPβ和SHP2的IC50分别为 126 nM，109 nM，26 nM 和 201 nM。
T1101	Minocycline hydrochloride Minocycline HCl,盐酸米诺环素,美满霉素	HIF/HIF Prolyl-Hydroxylase; Antibacterial; Antibiotic	Chromatin/Epigenetic; Metabolism; Microbiology/Virology
	Minocycline hydrochloride (Minocycline HCl) 属于四环素类抗生素，具有出色的吸收和组织渗透性。Minocycline hydrochloride 是一种广谱的抗菌剂，可用于多种细菌感染以及痤疮的治疗。
T6146	Dorsomorphin dihydrochloride BML-275 2HCl,Compound C dihydrochloride,6-[4-[2-(1-哌啶基)乙氧基]苯基]-3-(4-吡啶基)吡唑并[1,5-A]嘧啶,Dorsomorphin (Compound C) 2HCl,Compound C 2HCl,BML-275 dihydrochloride	AMPK; Autophagy; TGF-beta/Smad	Autophagy; Chromatin/Epigenetic; PI3K/Akt/mTOR signaling; Stem Cells
	Dorsomorphin dihydrochloride (BML-275 2HCl) 是一种 AMPK 抑制剂 (Ki=109 nM)，具有选择性和 ATP 竞争性。Dorsomorphin dihydrochloride 可以抑制 BMP I 型受体 ALK2、ALK3 和 ALK6。Dorsomorphin dihydrochloride 可诱导自噬，具有抗肿瘤活性。
T7797	Tasosartan 他索沙坦,WAY-ANA 756	RAAS	Endocrinology/Hormones
	Tasosartan (WAY-ANA 756) 是长效血管紧张素 II 受体拮抗剂。
T24488	MLS000545091 MLS-000545091,MLS 000545091	Others	Others
	MLS000545091 is a potent and selective human epithelial 15-lipoxygenase-2 mixed-type inhibitor.
T15053	Darodipine 达罗地平,PY-108068,PY 108-068	Calcium Channel	Membrane transporter/Ion channel; Metabolism
	Darodipine (PY-108068) 是钙离子通道的有效拮抗剂。
T2385	Ipragliflozin 伊格列净,ASP1941	SGLT	GPCR/G Protein
	Ipragliflozin (ASP1941) 是一种口服有效的，选择性的 SGLT2抑制剂，对人 SGLT2 和 SGLT1，大鼠 SGLT2 和 SGLT1，小鼠 SGLT2 和 SGLT1 的 IC50分别为 7.38 和 1876 nM，6.73 和 1166 nM，5.64 和 1380 nM。Ipragliflozin 具有抗糖尿病活性。
T26656	ARH-049020 ARH049020,X-334,X334,X 334,ARH 049020	PPAR	DNA Damage/DNA Repair; Metabolism
	ARH-049020 (ARH049020) 是一种 PPAR 激动剂，可用于研究 2 型糖尿病。
T71394	BMS-823778	Dehydrogenase	Metabolism
	BMS-823778 是一种高效的 11β-羟基类固醇脱氢酶 1 型（11β-HSD-1）的抑制剂，可用于研究 2 型糖尿病。
T67800	GR-95168	Antifection	Microbiology/Virology
	GR-95168 ((+)-C-BVDU) 是一种抗病毒化合物，可用于研究1型和2型单纯疱疹病毒感染。
T3476	JI-101 CGI-1842,JI 101	VEGFR; PDGFR; Ephrin Receptor	Angiogenesis; Tyrosine Kinase/Adaptors
	JI-101 (CGI-1842) 是一种有口服活性的多靶点激酶抑制剂，能够抑制VEGFR2，PDGFRβ和EphB4，具有抗癌作用。
T28182	NNC 92-1687 NNC92-1687,NNC-92-1687	Glucagon Receptor	GPCR/G Protein
	NNC 92-1687 是一种选择性胰高血糖素受体拮抗剂，可用于研究2型糖尿病。
T30142	ARRY-403 AMG-151,ARRY 403,ARRY403,ARRY-403,AMG151,AMG 151	Glucokinase	Metabolism
	ARRY-403 是一种新型葡萄糖激酶激活剂，可降低 2 型糖尿病患者的空腹和餐后血糖，可用于治疗糖尿病。
T3104	Globalagliatin LY2608204	Glucokinase	Metabolism
	Globalagliatin (LY2608204) 是一种葡萄糖激酶 (GK) 活化剂，EC50=42 nM。
T15440	GSK376501A	PPAR	DNA Damage/DNA Repair; Metabolism
	GSK376501A 是一种具有选择性和有效性的的过氧化物酶体增殖物激活受体 γ (PPARγ) 调节剂，可用于研究 2 型糖尿病。
T19101	2'-Fluorothymidine 2'-Deoxy-2'-fluoro-5-Methyluridine,2'-Deoxy-2'-fluoro-5-Methyluridine	Others	Others
	2'-Fluorothymidine(2'-Deoxy-2'-fluoro-5-Methyluridine) 属于胸腺嘧啶 (TdR) 和甲基尿苷的同工酶，是具有高度选择性的 2 型胸苷激酶 (TK2) 的底物。
T29019	TS-021 TS021,TS 021,TS-021 Free	DPP-4	Proteases/Proteasome
	TS-021 是一种具有选择性的二肽基肽酶 4 (DPP-4) 抑制剂，具有抗糖尿病活性，可用于研究2 型糖尿病。
T28757	Sergliflozin etabonate GW-869682,GW-869682X,KGT-1251,GW869682X,GW869682,KGT1251	SGLT	GPCR/G Protein
	Sergliflozin etabonate (KGT-1251) 是一种 SGLT-2 抑制剂，可用于 2 型糖尿病和肥胖症的研究。
T3104L	(1S,2R)-Globalagliatin (1S,2R)-Globalagliatin（1S,2R-1234703-40-2）	Glucokinase	Metabolism
	(1S,2R)-Globalagliatin 是一种高效的葡萄糖激酶 (GK) 激活剂，可用于研究 2 型糖尿病。
T26712	AZD-1656 AZD 1656	Glucokinase	Metabolism
	AZD-1656 是口服有效的葡萄糖激酶选择性激活剂，EC50为 60 nM。AZD1656在2 型糖尿病中有研究的价值。
T62512	IHMT-MST1-58	Hippo pathway	Stem Cells
	IHMT-MST1-58 是一种 STE20-like protein 1 kinase (MST1) 抑制剂（IC50 ：23 nM），具有高效性、选择性和口服活性。IHMT-MST1-58 可用于研究 1 型或 2 型糖尿病。
T1782	Canagliflozin 卡格列净,JNJ 24831754ZAE,JNJ 28431754AAA,TA 7284,JNJ 28431754	SGLT	GPCR/G Protein
	Canagliflozin (JNJ 28431754AAA) 是SGLT2的选择性抑制剂，在表达 mSGLT2，rSGLT2 和 hSGLT2 的 CHO 细胞上，IC50分别为 2 nM，3.7 nM 和 4.4 nM。
T3176	APD597 JNJ-38431055	GPR	Endocrinology/Hormones; GPCR/G Protein
	APD597 (JNJ-38431055) 是一种 GPR119 激动剂，能够作用于 hGPR119，EC50=46 nM，可用于 2 型糖尿病的研究。
T14900	CCR2-RA-[R] (5R)-4-乙酰基-1-(4-氯-2-氟苯基)-5-环己基-1,5-二氢-3-羟基-2H-吡咯-2-酮	CCR	Immunology/Inflammation; Microbiology/Virology
	CCR2-RA-[R] 是一种 C-C 趋化因子受体 2 型 (CCR2) 变构拮抗剂，IC50值为103 nM。
T19850L	Semaglutide Acetate 索玛鲁肽醋酸盐,Semaglutide Acetate(910463-68-2 Free base)	Glucagon Receptor	GPCR/G Protein
	Semaglutide Acetate 是胰高血糖素样肽 1 (GLP-1) 受体的激动剂，可用于治疗 2 型糖尿病的研究。
T27719	KD-026 SLx 4090,SLx4090,KD026,SLx-4090	CETP	Metabolism
	KD-026 (SLx 4090) 是具有口服活性的、肠细胞特异性的微粒体甘油三酯转移蛋白 (MTP)抑制剂，IC50为 8.0 nM。KD-026 (SLx 4090) 在糖尿病2型中有研究的价值。
T8511	TM38837	Cannabinoid Receptor	GPCR/G Protein
	TM38837 是外周选择性大麻素受体1型受体拮抗剂。它减少精神病副作用的倾向。它对大脑的渗透率有限，以降低或防止 CNS 不良反应，并保留潜在的抗肥胖作用。
T72617	Nampt activator-2	P450; NAMPT	Metabolism
	Nampt activator-2 是一种 NAMPT 激活剂（EC50 ： 0.023 μM）。 Nampt activator-2 对 CYP2C9、2D6、2C19 具有亲和力，亲和力数值分别为 0.060 μM、 0.41 μM 和 0.59 μM 。Nampt activator-2 可用来研究动脉粥样硬化，肥胖，II型糖尿病，胰岛素抵抗和I型糖尿病。
T37097	SET 2	TRP/TRPV Channel	Membrane transporter/Ion channel
	SET 2 是瞬时受体电位香草酸 2 型 (TRPV2) 的拮抗剂，IC50 为 0.46 μM。 SET 2 显示了对 TRPV1、TRPV3 和 TRPV4 的选择性。
T3041	ALK inhibitor 2	FAK; ALK	Angiogenesis; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors
	ALK inhibitor 2 是嘧啶类 ALK 的有效抑制剂。它是一种睾丸特异性丝氨酸/苏氨酸激酶 2 (TSSK2;IC50=37 nM) 和粘着斑激酶 (FAK;IC50=5 nM) 抑制剂。
T2316	Omarigliptin MK-3102,奥格列汀	Proteasome; DPP-4	Proteases/Proteasome; Ubiquitination
	Omarigliptin (MK-3102) 是高效选择性 DPP4抑制剂，IC50=为1.6nM。
TP1469	Lixisenatide acetate (320367-13-3 free base) Lixisenatide acetate	Glucagon Receptor	GPCR/G Protein
	Lixisenatide acetate 是一种胰高血糖素样肽 1 受体的激动剂，可用于研究 2 型糖尿病。
T67768	5-(2-Furyl)-2-hydroxybenzoic acid LDH-IN-2	Others	Others
	5-(2-Furyl)-2-hydroxybenzoic acid 是乙醇酸氧化酶 (GO) 抑制剂，可用于研究原发性高草酸尿症 1 型 (PH1) 等代谢相关的疾病。
TQ0241	TUG-770 TUG770,TUG 770	GPR	Endocrinology/Hormones; GPCR/G Protein
	TUG-770 是一种具有口服活性、选择性和高效性的 GPR40/FFA1 激动剂，具有潜在的抗炎活性。TUG-770 可用于研究 2 型糖尿病、痴呆和阿尔茨海默症。

化合物

C-Type Natriuretic Peptide (1-22) acetate（human）

Cat.No: T39392L

Synonym: C-Type Natriuretic Peptide (CNP) (1-22), human acetate(1966153-17-2 Free base)

Target: Others

Cat.No: T13867

Target: Others

Cat.No: T9022

Synonym: AZD 9977

Target: Glucocorticoid Receptor

Cat.No: T15159

Synonym: HMS5552

Target: Glucokinase

Cat.No: T15432

Target: GPR, Others

Cat.No: T14315

Synonym: APAU

Target: Epoxide Hydrolase

Cat.No: T3978

Synonym: GSK2330672,Iinerixibat

Target: HBV

Cat.No: T8944

Target: Calcium Channel

Cat.No: T16074

Synonym: SR-202,米福贝特

Target: PPAR

Cat.No: T1088

Synonym: AG-EE 388 ZW,AG-EE 623ZW,瑞格列奈

Target: Potassium Channel, PPAR

Cat.No: T21900

Synonym: (E)-2-((1,4-二甲基哌嗪-2-亚基)氨基)-5-硝基-N-苯基苯甲酰胺

Target: Others

Cat.No: T12302

Synonym: (Z)-N-[(2S)-1-hydroxy-3-(4-hydroxyphenyl)propan-2-yl]octadec-9-enamide

Target: Endogenous Metabolite

Cat.No: T1603

Synonym: CP 28720,K 4024,格列吡嗪

Target: Potassium Channel, PPAR, ABC

Kevetrin hydrochloride

Cat.No: T3184

Synonym: Thioureidobutyronitrile HCl,thioureido butyronitrile hydrochloride,4-Isothioureidobutyronitrile hydrochloride

Target: Mdm2, p53

T-Type calcium channel inhibitor 2

Cat.No: T64203

Target: Others

Adenylyl cyclase type 2 agonist-1

Cat.No: T63893

Target: Others

Bis(maltolato)oxovanadium(IV)

Cat.No: T22276

Synonym: 双(麦芽醇)氧钒(IV),BMOV,Bis maltolato oxovanadium,Bis(maltolato)oxovanadium (IV),bis maltolato oxo vanadium,Bis(maltolato)oxovanadium (IV)

Target: Phosphatase, Others

Minocycline hydrochloride

Cat.No: T1101

Synonym: Minocycline HCl,盐酸米诺环素,美满霉素

Target: HIF/HIF Prolyl-Hydroxylase, Antibacterial, Antibiotic

Dorsomorphin dihydrochloride

Cat.No: T6146

Synonym: BML-275 2HCl,Compound C dihydrochloride,6-[4-[2-(1-哌啶基)乙氧基]苯基]-3-(4-吡啶基)吡唑并[1,5-A]嘧啶,Dorsomorphin (Compound C) 2HCl,Compound C 2HCl,BML-275 dihydrochloride

Target: AMPK, Autophagy, TGF-beta/Smad

Cat.No: T7797

Synonym: 他索沙坦,WAY-ANA 756

Target: RAAS

Cat.No: T24488

Synonym: MLS-000545091,MLS 000545091

Target: Others

Cat.No: T15053

Synonym: 达罗地平,PY-108068,PY 108-068

Target: Calcium Channel

Cat.No: T2385

Synonym: 伊格列净,ASP1941

Target: SGLT

Cat.No: T26656

Synonym: ARH049020,X-334,X334,X 334,ARH 049020

Target: PPAR

Cat.No: T71394

Target: Dehydrogenase

Cat.No: T67800

Target: Antifection

Cat.No: T3476

Synonym: CGI-1842,JI 101

Target: VEGFR, PDGFR, Ephrin Receptor

Cat.No: T28182

Synonym: NNC92-1687,NNC-92-1687

Target: Glucagon Receptor

Cat.No: T30142

Synonym: AMG-151,ARRY 403,ARRY403,ARRY-403,AMG151,AMG 151

Target: Glucokinase

Cat.No: T3104

Synonym: LY2608204

Target: Glucokinase

Cat.No: T15440

Target: PPAR

2'-Fluorothymidine

Cat.No: T19101

Synonym: 2'-Deoxy-2'-fluoro-5-Methyluridine,2'-Deoxy-2'-fluoro-5-Methyluridine

Target: Others

Cat.No: T29019

Synonym: TS021,TS 021,TS-021 Free

Target: DPP-4

Sergliflozin etabonate

Cat.No: T28757

Synonym: GW-869682,GW-869682X,KGT-1251,GW869682X,GW869682,KGT1251

Target: SGLT

(1S,2R)-Globalagliatin

Cat.No: T3104L

Synonym: (1S,2R)-Globalagliatin（1S,2R-1234703-40-2）

Target: Glucokinase

Cat.No: T26712

Synonym: AZD 1656

Target: Glucokinase

Cat.No: T62512

Target: Hippo pathway

Cat.No: T1782

Synonym: 卡格列净,JNJ 24831754ZAE,JNJ 28431754AAA,TA 7284,JNJ 28431754

Target: SGLT

Cat.No: T3176

Synonym: JNJ-38431055

Target: GPR

Cat.No: T14900

Synonym: (5R)-4-乙酰基-1-(4-氯-2-氟苯基)-5-环己基-1,5-二氢-3-羟基-2H-吡咯-2-酮

Target: CCR

Semaglutide Acetate

Cat.No: T19850L

Synonym: 索玛鲁肽醋酸盐,Semaglutide Acetate(910463-68-2 Free base)

Target: Glucagon Receptor

Cat.No: T27719

Synonym: SLx 4090,SLx4090,KD026,SLx-4090

Target: CETP

Cat.No: T8511

Target: Cannabinoid Receptor

Nampt activator-2

Cat.No: T72617

Target: P450, NAMPT

Cat.No: T37097

Target: TRP/TRPV Channel

ALK inhibitor 2

Cat.No: T3041

Target: FAK, ALK

Cat.No: T2316

Synonym: MK-3102,奥格列汀

Target: Proteasome, DPP-4

Lixisenatide acetate (320367-13-3 free base)

Cat.No: TP1469

Synonym: Lixisenatide acetate

Target: Glucagon Receptor

5-(2-Furyl)-2-hydroxybenzoic acid

Cat.No: T67768

Synonym: LDH-IN-2

Target: Others

Cat.No: TQ0241

Synonym: TUG770,TUG 770

Target: GPR

Cat. No.	Product Name	Target	Signaling Pathways
T7544	Fucoidan 岩藻多糖	Others	Others
	Fucoidan 是一种 α-淀粉酶和 α-葡萄糖苷酶的有效抑制剂，是一种生物特性多糖。它具有抗凝血，抗肿瘤，抗氧化和抗脂肪特性。
T2210	Genipin 京尼平,(+)-Genipin	Others; Autophagy	Autophagy; Others
	Genipin ((+)-Genipin) 是衍生自黄栀果实的天然交联剂，可抑制细胞中的 UCP2 (解偶联蛋白 2)。它有蛋白质调节、抗肿瘤、抗炎症、免疫抑制、抗血栓形成和对海马神经元保护的多种生物活性，可研究 2 型糖尿病。
TN1418	Azaleatin 杜鹃黄素,2-(3,4-二羟基苯基)-3,7-二羟基-5-甲氧基苯并吡喃-4-酮	DPP-4	Proteases/Proteasome
	Azaleatin 是分离自Rhododendron 种中的 O-甲基化黄酮醇。它是二肽基肽酶-IV 的抑制剂。它在 2 型糖尿病和肥胖症中有研究的价值。
T0314	Hexylresorcinol 己雷锁辛,4-己基间苯二酚,4-Hexylresorcinol	Apoptosis; Tyrosinase; Antibacterial; Parasite	Apoptosis; Microbiology/Virology; Proteases/Proteasome
	Hexylresorcinol (4-Hexylresorcinol) 是在植物中发现的一种天然产物，具有抗菌、驱虫、防腐和抗肿瘤活性。它是一种可逆、非竞争性的 α-葡萄糖苷酶抑制剂，有抗 DNA 氧化损伤的保护作用。它可诱导鳞癌细胞凋亡。
T7132	(Rac)-Brassinazole BRASSINAZOLE,3-(4-氯苯基)-1-甲基-1-苯基-2-(1,2,4-三唑-1-基)-1-丙醇,(Rac)-芸苔素唑	P450	Metabolism
	(Rac)-Brassinazole 是三唑型化合物，是油菜素甾醇 (BR) 生物合成抑制剂。它能够增强 CYP90B 在 BR 生物合成中的抑制作用。
T20587	2-Acetonaphthone 2-萘乙酮,beta-Acetylnaphthalene,beta-Acetonaphthalene,2Acetylnaphthalene,2-Acetylnaphthalene,2 Acetylnaphthalene,beta-Naphthyl methyl ketone	Endogenous Metabolite	Metabolism
	2-Acetonaphthone (beta-Naphthyl methyl ketone) 是内源性代谢产物的一种。
T4948	Potassium 2-hydroxy-2-methylsuccinate (±)-柠苹酸钾一水合物,(±)-Potassium citramalate monohydrate,(±)-2-Hydroxy-2-methylsuccinic acid dipotassium salt	Others; Endogenous Metabolite	Metabolism; Others
	Potassium 2-hydroxy-2-methylsuccinate ((±)-2-Hydroxy-2-methylsuccinic acid dipotassium salt) 是内源性代谢产物的一种。
TCS1857	2-Phenylacetaldehyde Phenylacetaldehyde,Benzeneacetaldehyde,苯乙醛,Phenylethanal,Hyacinthin	Others; Endogenous Metabolite	Metabolism; Others
	2-Phenylacetaldehyde (Hyacinthin) 是内源性代谢产物的一种。
T3524	Halofuginone hydrobromide 卤夫酮溴氢酸盐,Tempostatin,RU-19110 (hydrobromide),Stenorol,常山酮溴酸盐	Others; Calcium Channel; DNA/RNA Synthesis; Sodium Channel; Parasite; TGF-beta/Smad	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Membrane transporter/Ion channel; Metabolism; Microbiology/Virology; Others; Stem Cells
	Halofuginone hydrobromid 是Febrifugine 的衍生物，是竞争性脯氨酰-tRNA 合成酶抑制剂。它是 I 型胶原合成的特异性抑制剂，并通过抑制TGF-β活性可减轻骨关节炎。它具有抗疟疾、抗炎、抗癌、抗纤维化作用。
T3829	Ginsenoside F3 人参皂苷F3	Others; IFNAR; Interleukin	Immunology/Inflammation; Others
	Ginsenoside F3 是一种皂苷，提取自Panax ginseng 叶片。它能够调节1 型 (IL-2, IFN-γ) 及 2 型细胞因子(IL-4 and IL-10) 的产生和表达，有免疫增强的作用。
T13280	Valerylcarnitine VALERYL-L-CARNITINE	Endogenous Metabolite	Metabolism
	Valerylcarnitine (VALERYL-L-CARNITINE) 是一种短链脂肪酸，可用于研究 2 型糖尿病。
T2S1992	Perillartine Perilla sugar,Peryllartine,紫苏葶,DL-Perillartine	Others; Endogenous Metabolite	Metabolism; Others
	Perillartine (DL-Perillartine) 是甜味剂，能够激活味觉受体 1 型成员 2 。
T38095	Acetylvaline Ac-Val-OH	Others	Others
	Acetylvaline (Ac-Val-OH) 可作为 2 型糖尿病、肥胖和视网膜病变等疾病的一个指标。
T3S1916	Heteroclitin D 异型南五味子丁素,异南五味子丁素；异型南五味子丁素	Calcium Channel	Membrane transporter/Ion channel; Metabolism
	Heteroclitin D 是异形南五味子中的一种木脂素，可抑制 L 型钙通道，具有抗脂质过氧化作用。
TN2277	Torachrysone-8-O-b-D-glucoside 芦荟大黄素 8-葡萄糖甙,Torachrysone 8-O-glucoside	Antifection	Microbiology/Virology
	Torachrysone-8-O-b-D-glucoside 可从 Polygonum multiflorum 分离得到。它对 DPCs(真皮乳头细胞)的增殖具有促进作用。
T17303	α-Cyclodextrin Alfadex,NSC269470,α-环糊精,NSC 269470,NSC-269470	Others	Others
	α-Cyclodextrin (Alfadex) 是一种多功能可溶性膳食纤维，可作为纤维原料销售。
T4322	2-Hydroxybutyric acid α-Hydroxybutyric acid	Endogenous Metabolite	Metabolism
	2-Hydroxybutyric acid (α-Hydroxybutyric acid) 是蛋白质代谢的产物，是 2 型糖尿病和先兆子痫的生物标志物，是合成生物降解材料和各种化合物的重要中间体。2-Hydroxybutyric acid 可预防 acetaminophen (AP) 引起的肝损伤，可参与抗肿瘤抗生素和可生物降解的聚（2-羟基丁酸）阿齐诺菊酯家族的合成。
T7846	Aegeline	Others; Antifungal	Microbiology/Virology; Others
	Aegeline 是从 Aegle marmelos 的叶子中分离出来的一种生物碱酰胺，有抗高血糖和抗血脂异常的活性。
TN1488	Chrysin 6-C-glucoside 8-C-arabinoside	Others	Others
	Chrysin 6-C-glucoside 8-C-arabinoside 是α±-葡萄糖苷酶抑制剂，α±-葡萄糖苷酶抑制剂广泛用于2型糖尿病的治疗。
TN1487	Chrysin 6-C-arabinoside 8-C-glucoside	Others	Others
	Chrysin 6-C-arabinoside 8-C-glucoside 是α±-葡萄糖苷酶抑制剂，α±-葡萄糖苷酶抑制剂广泛用于2型糖尿病的治疗。
T0461L	Berberine sulfate AI3-61947,Berberin sulfate,Berberine sulphate,Berberal
	Berberine sulfate (Berberal) 是苄基异喹啉生物碱原小檗碱类的季铵盐，可用于研究2型糖尿病、腹部肥胖和代谢相关脂肪性肝病。
T16442	PCO371 2,4-Imidazolidinedione, 1-(3,5-dimethyl-4-(2-((4-oxo-2-(4-(trifluoromethoxy)phenyl)-1,3,8-triazaspiro(4.5)dec-1-en-8-yl)sulfonyl)ethyl)phenyl)-5,5-dimethyl-	Thyroid hormone receptor(THR)	Endocrinology/Hormones
	PCO371 (2,4-Imidazolidinedione, 1-(3,5-dimethyl-4-(2-((4-oxo-2-(4-(trifluoromethoxy)phenyl)-1,3,8-triazaspiro(4.5)dec-1-en-8-yl)sulfonyl)ethyl)phenyl)-5,5-dimethyl-) 是口服具有活性的甲状旁腺激素受体 1 的完全激动剂，对 PTHR2 无作用
TN1475	Caulophyllogenin Segetalic acid	IL Receptor; TNF; PPAR; Immunology/Inflammation related	Apoptosis; DNA Damage/DNA Repair; Immunology/Inflammation; Metabolism
	Caulophyllogenin 是一种部分 PPARγ 激动剂 (EC50 = 12.6 μM)，来源于 Kalopanax pictus (五加科) 的茎皮。 Caulophyllogenin 抑制促炎细胞因子分泌，可用于预防和治疗炎症性疾病、2 型糖尿病、肥胖和代谢综合征的研究。
T4716	Pyrrole-2-carboxylic acid 吡咯-2-羧酸,2-Pyrrolecarboxylic acid,Minaline	Endogenous Metabolite	Metabolism
	Pyrrole-2-carboxylic acid (Minaline) 是一种天然生物碱类，从海洋细菌Pelomonas puraquaesp. Nov 中分离得到。
T25253	Cinnamtannin B-1 Cinnamtannin B1 (constituent of cinnamomum verum bark),LDN 0022358,LDN-0022358,LDN0022358,肉桂单宁B-1	Antioxidant; COX	Immunology/Inflammation; Neuroscience; oxidation-reduction
	Cinnamtannin B-1 (LDN 0022358) 是一种 A 型原花青素，包含在多种植物中，如越桔、桂树、泽兰肉桂和猪苓。它是一种有效的抗氧化剂和保护剂，可对抗人类血小板的氧化应激和凋亡。它是一种 Cox-2抑制剂。
T5S0620	3-Dehydrotrametenolic acid Dehydrotrametenolic acid,松苓新酸,3-氢化去氢松苓酸	Apoptosis; Others; Dehydrogenase	Apoptosis; Metabolism; Others
	3-Dehydrotrametenolic acid 是从茯苓菌核分离的一种乳酸脱氢酶抑制剂，可诱导细胞凋亡，具有抗癌活性。它促进体外脂肪细胞分化，在体内起胰岛素增敏剂的作用。
TN1132	Procyanidin A2 原花青素 A2,原花青素A2	IL Receptor; TNF; transporter; Antibacterial	Apoptosis; Immunology/Inflammation; Metabolism; Microbiology/Virology
	Procyanidin A2 是一种具有抗癌、抗氧化、抗菌和抗炎活性的黄酮类天然产物，存在于蔓越莓和越橘中。
TCS0102	Pulegone 胡薄荷酮,(+)-Pulegone,蒲勒酮，胡薄荷酮，长叶薄荷酮	Calcium Channel; Endogenous Metabolite; TRP/TRPV Channel	Membrane transporter/Ion channel; Metabolism
	Pulegone ((+)-Pulegone) 是 Calamintha nepeta (L.) Savi 的精油的主要化学成分，也是禽类驱虫剂之一。它在禽类物种中驱避作用的分子靶点是伤害感受性 TRP 锚蛋 1。它刺激鸡感觉神经元中的 TRPM8 和 TRPA1 通道，并在高浓度下抑制前者但不抑制后者。
T3394	Timosaponin BII 知母皂苷BII,Prototimosaponin A III	Beta Amyloid; Others; BACE	Neuroscience; Others
	Timosaponin BII (Prototimosaponin A III) 是一种甾体皂苷，发现于知母根茎中，具有神经保护、抗炎和抗氧化作用。
T1273	Diacerein 双醋瑞因,Diacerhein,Fisiodar,Diacetylrhein	IL Receptor; Interleukin	Immunology/Inflammation
	Diacerein (Fisiodar) 是一种慢效具有白介素-1β 抑制效果的蒽醌类化合物。
T5S0384	Rhapontin Ponticin,土大黄苷,Rhaponiticin,Rhaponticin,Rhapontigenin glucoside	Apoptosis; Others	Apoptosis; Others
	Rhapontin (Ponticin) 是药用大黄的一种成分，可减轻KK/Ay 糖尿病小鼠肝脏脂肪变性，改善血糖和血脂，表明其具有显着的降糖作用，有望成为治疗2型糖尿病及其并发症的新药。
T10024	1-Octanol Octanol,正辛醇	Calcium Channel; Endogenous Metabolite	Membrane transporter/Ion channel; Metabolism
	1-Octanol (Octanol) 是一种饱和脂肪醇，是一种 T 型钙通道抑制剂，对天然 T 电流的IC50为 4 μM。它是一种具有类似柴油特性的极具吸引力的生物燃料。
T2S1792	Lycobetaine 石蒜内胺,Ungeremine,石蒜醋胺,石蒜碱内铵盐	Antibacterial	Microbiology/Virology
	Lycobetaine (Ungeremine) 是一种潜在的抗罗克福尔青霉和黑曲霉的生物杀菌剂。它对柱状黄杆菌有很强的抗菌活性。它有效地靶向哺乳动物以及细菌I 型和II 型拓扑异构酶。它显示出强烈的乙酰胆碱酯酶抑制活性（IC(50) 值为 0.35 microM）。它具有抗原生动物活性，在体外试验中对Trypanosoma brucei rhodesiense、T. cruzi 表现出良好的活性。
T6S1885	Benzoylmesaconine Mesaconine 14-benzoate,苯甲酰新乌头原碱	Others	Others
	Benzoylmesaconine (Mesaconine 14-benzoate) 是乌头汤最丰富的组分。其中乌头汤可用于研究类风湿性关节炎。
T5303	Isethionic acid sodium salt Sodium isethionate,羟乙基磺酸钠	Others; Endogenous Metabolite	Metabolism; Others
	Isethionic acid sodium salt (Sodium isethionate) 是内源性代谢产物的一种。
T6S0659	Rhynchophylline 钩藤碱,Rhynchophyllin,Rhyncophylline,Mitrinermine,Mitrinermin	Calcium Channel; NF-κB	Membrane transporter/Ion channel; Metabolism; NF-κB
	Rhynchophylline (Mitrinermine) 是一种生物碱类化合物，从钩藤中分离得到，具有很高的生物活性，被广泛用于抗炎、神经保护等方面的研究。
T3822	Bellidifolin Bellidifoline,龙胆山酮酚,Bellidifolium,雏菊叶龙胆酮	Others; HIV Protease	Microbiology/Virology; Others; Proteases/Proteasome
	Bellidifolin (Bellidifoline) 是从獐牙菜的茎中提取的一种呫吨酮，它能作为病毒蛋白 R 的抑制剂，具有保肝、降血糖、抗炎、抗氧化、抗肿瘤作用。
T5S0018	Betulonic acid 路路通酸,(+)-Betulonic acid,Betunolic acid,Liquidambaric acid	Parasite; HSV	Microbiology/Virology
	Betulonic acid (Liquidambaric acid) 是一种在许多植物中存在的三萜类天然产物，具有抗肿瘤，抗炎，抗寄生虫和抗病毒的活性。
T6S1699	Shogaol [6]-Shogaol,姜烯酚,6-姜烯酚,6-Shogaol	Lipoxygenase; Autophagy	Autophagy; Metabolism
	6-Shogaol (6-Shogaol) 是从生姜中分离的一种天然产物，具有抗癌、抗炎和抗氧化的多种生物活性。
T2973	Astragaloside IV AST-IV,黄芪甲苷IV,AS-IV,黄芪皂苷 IV	MMP; ERK; Estrogen/progestogen Receptor; JNK	Endocrinology/Hormones; MAPK; Proteases/Proteasome
	Astragaloside IV (AS-IV) 是从黄芪中分离得到的一种皂苷，抑制ERK1/2和JNK 激活，在乳腺癌细胞 MDA-MB-231 中，下调(MMP)-2和(MMP)-9的信号通路。
T2940	6-Hydroxyflavone 6-羟基黄酮,6-HF	GABA Receptor	Membrane transporter/Ion channel; Neuroscience
	6-Hydroxyflavone (6-HF) 是天然存在的黄酮化合物，具有抗炎作用。它对牛血红蛋白糖基化具有抑制作用。它能激活 AKT、ERK 1/2、JNK 信号通路，有效促进成骨细胞分化。它能抑制 LPS 诱导的 NO 的产生。
T3417	Amentoflavone Didemethyl-ginkgetin,穗花杉双黄酮,Amenthoflavone,3',8''-Biapigenin	Apoptosis; P450; Phospholipase; Reactive Oxygen Species; Opioid Receptor; COX; Antibacterial; RSV; Antifungal	Apoptosis; Endocrinology/Hormones; GPCR/G Protein; Immunology/Inflammation; Metabolism; Microbiology/Virology; Neuroscience; NF-κB
	Amentoflavone (3',8''-Biapigenin) 是一种具有很多生物活性的双黄酮类天然产物，有抗炎、抗氧化和神经保护等作用。
T2S1865	Octyl gallate Gallic acid octyl ester,n-Octylgallate,Octyl 3,4,5-trihydroxybenzoate,Progallin O,Stabilizer GA-8,没食子酸辛酯	Antioxidant; Influenza Virus; Reactive Oxygen Species; Antibacterial; Antifungal; HSV	Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB; oxidation-reduction
	Octyl gallate (Octyl 3,4,5-trihydroxybenzoate) 具有抗菌、抗氧化作用，有选择性和敏感性的荧光特性，广泛用作食品添加剂。它对 HSV-1，水泡性口炎病毒和脊髓灰质炎病毒有显著的抗病毒作用。
T3S1612	kuwanon G 桑黄酮G,Moracenin B,桑黄酮 G,Kuwanone G	Phosphatase; Antibacterial; Bombesin Receptor; AChR; AChE; Glucosidase	GPCR/G Protein; Metabolism; Microbiology/Virology; Neuroscience
	Kuwanon G (Moracenin B) 是一种从桑树中得到的黄酮类蛙皮素受体拮抗剂，具有杀菌作用。
T4723	D-Tagatose 塔格糖,D-(-)-Tagatose,D-塔格糖,d-tagatos	Others; Endogenous Metabolite	Metabolism; Others
	D-Tagatose (D-(-)-Tagatose) 是自然界中发现的一种罕见的单糖，具有益生元特性。它是研究II 型糖尿病的潜在抗糖尿病药物，也是帮助提升结肠有益细菌、预防结肠癌和抑制胆固醇的益生元。它是蔗糖的替代品，也是口香糖、果汁和饮料等食品中的低热量甜味剂。
T8274	3-Methyl-L-histidine	Endogenous Metabolite	Metabolism
	3-Methyl-L-histidine 是一种肉类尤其是鸡肉摄入和大豆制品摄入的生物标记。
T29360	2-Nonanone 2Nonanone,Ketone, heptyl methyl,Heptyl methyl ketone,2 Nonanone
	2-Nonanone is a flavor and fragrance agent with a fruity type odor and a cheesy type flavor.
T27281	Eritoran Tetrasodium B 1287,E 5564,B-1287,E5564,B1287,E-5564	Others	Others
	Eritoran Tetrasodium, a TLR4 receptor antagonist, is used potentially for the treatment of type 2 diabetes.
T83262	6-Methoxy-2-[2-(3′-methoxyphenyl)ethyl]chromone
	6-Methoxy-2-[2-(3′-methoxyphenyl)ethyl]chromone（化合物12）是一种色满酮类化合物。
TN5234	Vindorosine	Calcium Channel; Sodium Channel	Membrane transporter/Ion channel; Metabolism
	Vindorosine has blood vessel relaxation effect, possible underlying mechanisms involving the inhibition of Ca(2+) entry via L-type Ca(2+) channels in vascular smooth muscles.
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天然产物

Cat.No: T7544

Synonym: 岩藻多糖

Target: Others

Cat.No: T2210

Synonym: 京尼平,(+)-Genipin

Target: Others, Autophagy

Cat.No: TN1418

Synonym: 杜鹃黄素,2-(3,4-二羟基苯基)-3,7-二羟基-5-甲氧基苯并吡喃-4-酮

Target: DPP-4

Hexylresorcinol

Cat.No: T0314

Synonym: 己雷锁辛,4-己基间苯二酚,4-Hexylresorcinol

Target: Apoptosis, Tyrosinase, Antibacterial, Parasite

(Rac)-Brassinazole

Cat.No: T7132

Synonym: BRASSINAZOLE,3-(4-氯苯基)-1-甲基-1-苯基-2-(1,2,4-三唑-1-基)-1-丙醇,(Rac)-芸苔素唑

Target: P450

2-Acetonaphthone

Cat.No: T20587

Synonym: 2-萘乙酮,beta-Acetylnaphthalene,beta-Acetonaphthalene,2Acetylnaphthalene,2-Acetylnaphthalene,2 Acetylnaphthalene,beta-Naphthyl methyl ketone

Target: Endogenous Metabolite

Potassium 2-hydroxy-2-methylsuccinate

Cat.No: T4948

Synonym: (±)-柠苹酸钾一水合物,(±)-Potassium citramalate monohydrate,(±)-2-Hydroxy-2-methylsuccinic acid dipotassium salt

Target: Others, Endogenous Metabolite

2-Phenylacetaldehyde

Cat.No: TCS1857

Synonym: Phenylacetaldehyde,Benzeneacetaldehyde,苯乙醛,Phenylethanal,Hyacinthin

Target: Others, Endogenous Metabolite

Halofuginone hydrobromide

Cat.No: T3524

Synonym: 卤夫酮溴氢酸盐,Tempostatin,RU-19110 (hydrobromide),Stenorol,常山酮溴酸盐

Target: Others, Calcium Channel, DNA/RNA Synthesis, Sodium Channel, Parasite, TGF-beta/Smad

Cat.No: T3829

Synonym: 人参皂苷F3

Target: Others, IFNAR, Interleukin

Valerylcarnitine

Cat.No: T13280

Synonym: VALERYL-L-CARNITINE

Target: Endogenous Metabolite

Cat.No: T2S1992

Synonym: Perilla sugar,Peryllartine,紫苏葶,DL-Perillartine

Target: Others, Endogenous Metabolite

Cat.No: T38095

Synonym: Ac-Val-OH

Target: Others

Cat.No: T3S1916

Synonym: 异型南五味子丁素,异南五味子丁素；异型南五味子丁素

Target: Calcium Channel

Torachrysone-8-O-b-D-glucoside

Cat.No: TN2277

Synonym: 芦荟大黄素 8-葡萄糖甙,Torachrysone 8-O-glucoside

Target: Antifection

α-Cyclodextrin

Cat.No: T17303

Synonym: Alfadex,NSC269470,α-环糊精,NSC 269470,NSC-269470

Target: Others

2-Hydroxybutyric acid

Cat.No: T4322

Synonym: α-Hydroxybutyric acid

Target: Endogenous Metabolite

Cat.No: T7846

Target: Others, Antifungal

Chrysin 6-C-glucoside 8-C-arabinoside

Cat.No: TN1488

Target: Others

Chrysin 6-C-arabinoside 8-C-glucoside

Cat.No: TN1487

Target: Others

Berberine sulfate

Cat.No: T0461L

Synonym: AI3-61947,Berberin sulfate,Berberine sulphate,Berberal

Cat.No: T16442

Synonym: 2,4-Imidazolidinedione, 1-(3,5-dimethyl-4-(2-((4-oxo-2-(4-(trifluoromethoxy)phenyl)-1,3,8-triazaspiro(4.5)dec-1-en-8-yl)sulfonyl)ethyl)phenyl)-5,5-dimethyl-

Target: Thyroid hormone receptor(THR)

Caulophyllogenin

Cat.No: TN1475

Synonym: Segetalic acid

Target: IL Receptor, TNF, PPAR, Immunology/Inflammation related

Pyrrole-2-carboxylic acid

Cat.No: T4716

Synonym: 吡咯-2-羧酸,2-Pyrrolecarboxylic acid,Minaline

Target: Endogenous Metabolite

Cinnamtannin B-1

Cat.No: T25253

Synonym: Cinnamtannin B1 (constituent of cinnamomum verum bark),LDN 0022358,LDN-0022358,LDN0022358,肉桂单宁B-1

Target: Antioxidant, COX

3-Dehydrotrametenolic acid

Cat.No: T5S0620

Synonym: Dehydrotrametenolic acid,松苓新酸,3-氢化去氢松苓酸

Target: Apoptosis, Others, Dehydrogenase

Cat.No: TN1132

Synonym: 原花青素 A2,原花青素A2

Target: IL Receptor, TNF, transporter, Antibacterial

Cat.No: TCS0102

Synonym: 胡薄荷酮,(+)-Pulegone,蒲勒酮，胡薄荷酮，长叶薄荷酮

Target: Calcium Channel, Endogenous Metabolite, TRP/TRPV Channel

Timosaponin BII

Cat.No: T3394

Synonym: 知母皂苷BII,Prototimosaponin A III

Target: Beta Amyloid, Others, BACE

Cat.No: T1273

Synonym: 双醋瑞因,Diacerhein,Fisiodar,Diacetylrhein

Target: IL Receptor, Interleukin

Cat.No: T5S0384

Synonym: Ponticin,土大黄苷,Rhaponiticin,Rhaponticin,Rhapontigenin glucoside

Target: Apoptosis, Others

Cat.No: T10024

Synonym: Octanol,正辛醇

Target: Calcium Channel, Endogenous Metabolite

Cat.No: T2S1792

Synonym: 石蒜内胺,Ungeremine,石蒜醋胺,石蒜碱内铵盐

Target: Antibacterial

Benzoylmesaconine

Cat.No: T6S1885

Synonym: Mesaconine 14-benzoate,苯甲酰新乌头原碱

Target: Others

Isethionic acid sodium salt

Cat.No: T5303

Synonym: Sodium isethionate,羟乙基磺酸钠

Target: Others, Endogenous Metabolite

Rhynchophylline

Cat.No: T6S0659

Synonym: 钩藤碱,Rhynchophyllin,Rhyncophylline,Mitrinermine,Mitrinermin

Target: Calcium Channel, NF-κB

Cat.No: T3822

Synonym: Bellidifoline,龙胆山酮酚,Bellidifolium,雏菊叶龙胆酮

Target: Others, HIV Protease

Cat.No: T5S0018

Synonym: 路路通酸,(+)-Betulonic acid,Betunolic acid,Liquidambaric acid

Target: Parasite, HSV

Cat.No: T6S1699

Synonym: [6]-Shogaol,姜烯酚,6-姜烯酚,6-Shogaol

Target: Lipoxygenase, Autophagy

Astragaloside IV

Cat.No: T2973

Synonym: AST-IV,黄芪甲苷IV,AS-IV,黄芪皂苷 IV

Target: MMP, ERK, Estrogen/progestogen Receptor, JNK

6-Hydroxyflavone

Cat.No: T2940

Synonym: 6-羟基黄酮,6-HF

Target: GABA Receptor

Cat.No: T3417

Synonym: Didemethyl-ginkgetin,穗花杉双黄酮,Amenthoflavone,3',8''-Biapigenin

Target: Apoptosis, P450, Phospholipase, Reactive Oxygen Species, Opioid Receptor, COX, Antibacterial, RSV, Antifungal

Cat.No: T2S1865

Synonym: Gallic acid octyl ester,n-Octylgallate,Octyl 3,4,5-trihydroxybenzoate,Progallin O,Stabilizer GA-8,没食子酸辛酯

Target: Antioxidant, Influenza Virus, Reactive Oxygen Species, Antibacterial, Antifungal, HSV

Cat.No: T3S1612

Synonym: 桑黄酮G,Moracenin B,桑黄酮 G,Kuwanone G

Target: Phosphatase, Antibacterial, Bombesin Receptor, AChR, AChE, Glucosidase

Cat.No: T4723

Synonym: 塔格糖,D-(-)-Tagatose,D-塔格糖,d-tagatos

Target: Others, Endogenous Metabolite

3-Methyl-L-histidine

Cat.No: T8274

Target: Endogenous Metabolite

Cat.No: T29360

Synonym: 2Nonanone,Ketone, heptyl methyl,Heptyl methyl ketone,2 Nonanone

Eritoran Tetrasodium

Cat.No: T27281

Synonym: B 1287,E 5564,B-1287,E5564,B1287,E-5564

Target: Others

6-Methoxy-2-[2-(3′-methoxyphenyl)ethyl]chromone

Cat.No: T83262

Cat.No: TN5234

Target: Calcium Channel, Sodium Channel

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Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPJ-00335	TGFBR2 Protein, Mouse, Recombinant (His) TGFR-2,TGF-beta type II receptor,Transform...	Mouse	HEK293 Cells
	TGFBR2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 25-38 KDa and the accession number is Q62312-2.
TMPY-03079	IL-1R2 Protein, Mouse, Recombinant (His) interleukin 1 receptor, type II,Il1r-2,CD1...	Mouse	HEK293 Cells
	IL-1R2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39.6 kDa and the accession number is P27931.
TMPY-01677	VE-Cadherin Protein, Human, Recombinant (His & hFc) cadherin 5, type 2 (vascular endothelium),...	Human	HEK293 Cells
	VE-Cadherin Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 92 kDa and the accession number is P33151-1.
TMPY-01744	ACVR2A Protein, Human, Recombinant (His) activin A receptor, type IIA,ACVR2,ACTRII	Human	HEK293 Cells
	ACVR2A Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.9 kDa and the accession number is P27037-1.
TMPY-01050	Cadherin 6/CDH6 Protein, Human, Recombinant (His) CAD6,cadherin 6, type 2, K-cadherin (fetal...	Human	HEK293 Cells
	Cadherin 6/CDH6 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 68 kDa and the accession number is P55285-1.
TMPY-03484	TCPTP Protein, Human, Recombinant TCPTP,protein tyrosine phosphatase, non-receptor type	Human	Baculovirus Insect Cells
	TCPTP Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 36.8 kDa and the accession number is P17706-1.
TMPY-01143	N Cadherin Protein, Human, Recombinant (His) CDHN,CDw325,NCAD,CD325,cadherin 2...	Human	HEK293 Cells
	N Cadherin Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 78.5 kDa and the accession number is A0A024RC42.
TMPY-01366	IL-1R2 Protein, Human, Recombinant (His) IL1R2c,interleukin 1 receptor, type II,IL-...	Human	HEK293 Cells
	IL-1R2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39.2 kDa and the accession number is P27930-1.
TMPY-02231	TrkB Protein, Mouse, Recombinant (His) trk-B,neurotrophic tyrosine kinase, receptor, type ...	Mouse	HEK293 Cells
	TrkB Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46 kDa and the accession number is P15209-2.
TMPY-00586	CLEC-2 Protein, Mouse, Recombinant (hFc) 1810061I13Rik,Clec2,C-type lectin domain f...	Mouse	HEK293 Cells
	CLEC-2 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.1 kDa and the accession number is Q9JL99-1.
TMPY-03481	IL-1R2 Protein, Human, Recombinant 白细胞介素,IL1R2c,IL1RB,IL-1RT2,IL-1RT-2	Human	HEK293 Cells
	IL-1R2 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 38.4 kDa and the accession number is P27930-1.
TMPY-04774	ALK-2/ACVR1 Protein, Human, Recombinant (His) TSRI,ACVRLK2,FOP,activin A receptor, type ...	Human	Baculovirus Insect Cells
	ALK-2/ACVR1 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 12.8kDa and the accession number is Q04771.
TMPY-00751	TrkB Protein, Human, Recombinant (His) trk-B,GP145-TrkB/GP95-TrkB,neurotrophic tyrosine kinase, rec...	Human	HEK293 Cells
	TrkB Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 45.7 kDa and the accession number is Q16620-2.
TMPH-03542	Enterotoxin type C-2 Protein, S. aureus, Recombinant Enterotoxin type C-2,entC2,SEC	Staphylococcus aureus	E. coli
	Staphylococcal enterotoxin that activates the host immune system by binding as unprocessed molecules to major histocompatibility (MHC) complex class II and T-cell receptor (TCR) molecules. In turn, this ternary complex activates a large number of T-lymphocytes initiating a systemic release of proinflammatory cytokines. Causes also the intoxication staphylococcal food poisoning syndrome. Enterotoxin type C-2 Protein, S. aureus, Recombinant is expressed in E. coli expression system. The predicted ...
TMPH-03541	Enterotoxin type C-2 Protein, S. aureus, Recombinant (His & SUMO) Enterotoxin type C-2,SEC2,entC	Staphylococcus aureus	E. coli
	Staphylococcal enterotoxin that activates the host immune system by binding as unprocessed molecules to major histocompatibility (MHC) complex class II and T-cell receptor (TCR) molecules. In turn, this ternary complex activates a large number of T-lymphocytes initiating a systemic release of proinflammatory cytokines. Causes also the intoxication staphylococcal food poisoning syndrome. Enterotoxin type C-2 Protein, S. aureus, Recombinant (His & SUMO) is expressed in E. coli expression system wi...
TMPH-03488	Metallo-beta-lactamase type 2 Protein, Serratia marcescens, Recombinant (His & Myc) Metallo-beta-lactamase type 2,BLA-IMP,Meta...	Serratia marcescens	E. coli
	Confers resistance to the different beta-lactams antibiotics (penicillin, cephalosporin and carbapenem) via the hydrolysis of the beta-lactam ring. Metallo-beta-lactamase type 2 Protein, Serratia marcescens, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 32.6 kDa and the accession number is P52699.
TMPH-01031	CAPN2 Protein, Human, Recombinant (His) Calpain-2 catalytic subunit,Millimolar-calpain,Calp...	Human	E. coli
	Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Proteolytically cleaves MYOC at 'Arg-226'. Proteolytically cleaves CPEB3 following neuronal stimulation which abolishes CPEB3 translational repressor activity, leading to translation of CPEB3 target mRNAs. CAPN2 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 82...
TMPY-01168	ALK-1 Protein, Human, Recombinant (His) ALK1,ALK-1,activin A receptor type II-like 1,HHT	Human	HEK293 Cells
	ALK-1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 12.3 kDa and the accession number is A0A0S2Z310.
TMPY-02971	CLEC10A Protein, Human, Recombinant (hFc) HML2,CD301,CLECSF13,HML,MGL,C-type lectin ...	Human	HEK293 Cells
	CLEC10A Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 54.6 kDa and the accession number is Q8IUN9-2.
TMPJ-00778	HER2/ERBB2 Protein, Human, Recombinant (His) TKR1,Metastatic lymph node gene 19 protein,ERBB2,Pr...	Human	HEK293 Cells
	HER2/ERBB2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 90-120 KDa and the accession number is P04626.
TMPH-02373	Metallo-beta-lactamase type 2 Protein, Klebsiella pneumoniae, Recombinant (His) Metallo-beta-lactamase type 2,B2 ...	Klebsiella pneumoniae	E. coli
	Confers resistance to the different beta-lactams antibiotics (penicillin, cephalosporin and carbapenem) via the hydrolysis of the beta-lactam ring. Does not confer resistance to the polymixin colistin or the fluoroquinolone ciprofloxacin.
TMPY-02092	CLEC12A/MICL/CLL-1 Protein, Human, Recombinant (His) HECL,CLL-1,CD303,PRO34150,DCAL-2,CLL1,DLEC,CLECSF11...	Human	HEK293 Cells
	CLEC12A/MICL/CLL-1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 41~45 kDa and the accession number is EAW96132.1.
TMPY-01059	BMPR2 Protein, Human, Recombinant (His) POVD1,PPH1,BMPR3,BRK-3,BMPR-II,bone morphogenetic protein re...	Human	HEK293 Cells
	BMPR2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.6 kDa and the accession number is Q13873.
TMPY-03681	Cadherin 8/CDH8 Protein, Rat, Recombinant cadherin 8, type 2	Rat	HEK293 Cells
	Cadherin 8/CDH8 Protein, Rat, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 59.2 kDa and the accession number is A0A8I6AFP6.
TMPY-03372	Cadherin 8/CDH8 Protein, Rat, Recombinant (His) cadherin 8, type 2	Rat	HEK293 Cells
	Cadherin 8/CDH8 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 66.5 kDa and the accession number is A0A8I6AFP6.
TMPY-04045	Hemojuvelin Protein, Cynomolgus, Recombinant (His) hemochromatosis type 2 (juvenile)	Cynomolgus	Baculovirus Insect Cells
	Hemojuvelin Protein, Cynomolgus, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 40.2 kDa and the accession number is A0A2K5TJX5.
TMPY-03809	COL5A2 Protein, Human, Recombinant (mFc) collagen, type V, α2,collagen, type	Human	HEK293 Cells
	COL5A2 is a component of type V collagen. It is known as the pro-alpha2(V) chain. COL5A2, together with two pro-alpha1(V) chains can form type V procollagen. These triple-stranded, rope-like procollagen molecules arrange themselves into long, thin fibrils that cross-link to one another in the spaces around cells. The cross-links result in the formation of very strong, mature type V collagen fibers. Type V collagen can be detected in tissues containing type I collagen and appears to regulate the ...
TMPY-04005	CDH18 Protein, Rhesus, Recombinant (His) cadherin 18, type 2	Rhesus	HEK293 Cells
	CDH18 Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 66.4 kDa and the accession number is A0A8J8XSY9.
TMPY-01038	Cadherin 8/CDH8 Protein, Human, Recombinant (His) cadherin 8, type 2,Nbla04261	Human	HEK293 Cells
	Cadherin 8/CDH8 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 66.6 kDa and the accession number is P55286.
TMPK-00574	MRC2 Protein, Canine, Recombinant (His) Mannose receptor C type 2	Canine	HEK293 Cells
	MRC2 (Mannose Receptor C Type 2) is a constitutively recycling endocytic receptor belonging to the mannose receptor family, which has been found to be closely involved with cancer metastasis. MRC2 expresses an extracellular fibronectin type II domain that binds to and internalizes collagen, suggesting that it may play a role in modulating renal fibrosis. MRC2 Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 57.76 kDa and ...
TMPY-02917	TrkB Protein, Rat, Recombinant (hFc) neurotrophic tyrosine kinase, receptor, type 2<...	Rat	HEK293 Cells
	TrkB Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 71.5 kDa and the accession number is Q63604-1.
TMPY-03305	VE-Cadherin Protein, Rat, Recombinant (His) cadherin 5, type 2 (vascular endothelium)	Rat	HEK293 Cells
	VE-Cadherin Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 65.1 kDa and the accession number is A6JXX3.
TMPY-03635	TrkB Protein, Canine, Recombinant (His) neurotrophic tyrosine kinase, receptor, type 2<...	Canine	HEK293 Cells
	TrkB Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 43.7 kDa and the accession number is XP_541264.2.
TMPY-03162	TrkB Protein, Rat, Recombinant (His) neurotrophic tyrosine kinase, receptor, type 2<...	Rat	HEK293 Cells
	TrkB Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 47.1 kDa and the accession number is Q63604.
TMPY-00228	TrkB Protein, Canine, Recombinant (hFc) neurotrophic tyrosine kinase, receptor, type 2<...	Canine	HEK293 Cells
	TrkB Protein, Canine, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 71.2 kDa and the accession number is XP_541264.2.
TMPY-02298	ACYP2 Protein, Human, Recombinant (GST) ACYM,acylphosphatase 2, muscle type,ACYP	Human	E. coli
	Recent genome-wide association studies have identified genetic variants in ACYP2 and WFS1 that are associated with cisplatin-induced ototoxicity. We sought to explore the role of these genetic susceptibility factors to cisplatin-induced ototoxicity in patients with testicular cancer. Telomere length, as a marker of biological aging, has been reported to influence the risk of several age-related diseases, including ischemic stroke. Recent studies have identified the genetic variant within ACYP2 a...
TMPY-01172	CDH12 Protein, Human, Recombinant (His) CDHB,cadherin 12, type 2 (N-cadhe...	Human	HEK293 Cells
	Classic Cadherins represent a family of calcium-dependent homophilic cell-cell adhesion molecules. They confer strong adhesiveness to animal cells when they are anchored to the actin cytoskeleton via their cytoplasmic binding partners, catenins. The cadherin/catenin adhesion system plays key roles in the morphogenesis and function of the vertebrate and invertebrate nervous systems. Furthermore, this system is involved in synaptic plasticity. Recent studies on the role of individual cadherin subt...
TMPJ-01058	ARG2 Protein, Human, Recombinant (His) ARG2,Kidney-type arginase,Type II...	Human	E. coli
	Arginase-2 (ARG2) is a member of the arginase family. Arginase is a manganese-containing enzyme which catalyzes the hydrolysis of arginine to ornithine and urea. ARG2 is highly expressed in kidney and prostate, not founded in the liver, heart and pancreas. ARG2 has been implicated in the regulation of the arginine/ornithine concentrations in the cell. ARG2 may take part in the regulation of extra-urea cycle arginine metabolism and in down-regulation of nitric oxide synthesis. The extrahepatic ar...
TMPJ-00334	TGFBR2 Protein, Mouse, Recombinant (aa 24-159, hFc) TGF-β receptor type II,Tgfbr2,TGF-β recept...	Mouse	HEK293 Cells
	TGFBR2 Protein, Mouse, Recombinant (aa 24-159, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 55-65 KDa and the accession number is Q62312-2.
TMPH-02268	AGTR2 Protein, Human, Recombinant (His & SUMO) AT2 receptor,Angiotensin II type-2	Human	E. coli
	Receptor for angiotensin II. Cooperates with MTUS1 to inhibit ERK2 activation and cell proliferation.
TMPJ-00333	TGFBR2 Protein, Mouse, Recombinant (aa 24-184, hFc) Transforming growth factor-β receptor type II,Tbeta...	Mouse	HEK293 Cells
	TGFBR2 Protein, Mouse, Recombinant (aa 24-184, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 60-75 KDa and the accession number is Q62312.
TMPK-00980	EPhA2 Protein, Cynomolgus, Recombinant (hFc) EC:2.7.10.1,Ephrin type-A receptor 2	Cynomolgus	HEK293 Cells
	Ephrin type-A receptor 2 (EPHA2) is a receptor tyrosine kinase (RTK), whose over-expression has been observed in a variety of cancers, including breast cancer. EPHA2 expression may be causally related to tumorigenesis; therefore, it is important to understand how EPHA2 gene (EPHA2) expression is regulated. EPhA2 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 83.1 kDa and the accession number is Q1KL86.
TMPK-00979	EPhA2 Protein, Cynomolgus, Recombinant (His & Avi) EPHA2,EC:2.7.10.1,Ephrin type-A r...	Cynomolgus	HEK293 Cells
	Ephrin type-A receptor 2 (EPHA2) is a receptor tyrosine kinase (RTK), whose over-expression has been observed in a variety of cancers, including breast cancer. EPHA2 expression may be causally related to tumorigenesis; therefore, it is important to understand how EPHA2 gene (EPHA2) expression is regulated. EPhA2 Protein, Cynomolgus, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 59.2 kDa and the accession number is Q1KL86.
TMPY-05347	Cadherin 6/CDH6 Protein, Cynomolgus, Recombinant (His) cadherin 6, type 2, K-cadherin (fetal kidn...	Cynomolgus	HEK293 Cells
	Cadherin 6/CDH6 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 67.5 kDa and the accession number is XP_005556691.1.
TMPY-00311	Cadherin 6/CDH6 Protein, Rat, Recombinant (His) cadherin 6, type 2, K-cadherin (fetal kidn...	Rat	HEK293 Cells
	Cadherin 6/CDH6 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 67.9 kDa and the accession number is A6KJN4.
TMPY-04040	CLEC2D Protein, Rat, Recombinant (hFc) C-type lectin domain family 2, member D	Rat	HEK293 Cells
	Lectin-like transcript 1 (LLT1) encoded by CLEC2D gene is a C-type lectin-like molecule interacting with human CD161 (NKR-P1A) receptor expressed by natural killer cells and subsets of T cells. CLEC2D transcripts were detected primarily in hematopoietic cell lines and were found to be co-induced by the same activation signals. Although very low amounts of putative soluble CLEC2D protein isoforms could be produced by transfectants, CLEC2D isoforms 2 and 4 were efficiently expressed. CLEC2D uses g...
TMPJ-00424	EphB2 Protein, Human, Recombinant (hFc) EPHB2,Ephrin type-B receptor 2,EP...	Human	HEK293 Cells
	Ephrin type-B receptor 2(EPHB2) belongs to the protein kinase superfamily and Ephrin receptor subfamily. EPHB2 contains 1 Eph LBD domain, 2 fibronectin type-III domains, 1 protein kinase domain and 1 SAM domain. Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphospha...
TMPY-03078	IL-1R2 Protein, Mouse, Recombinant (hFc) CD121b,interleukin 1 receptor, type II,Il1...	Mouse	HEK293 Cells
	IL-1R2 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 65.1 kDa and the accession number is P27931.
TMPY-00574	PILRA Protein, Human, Recombinant (hFc) FDF03,paired immunoglobin-like type 2 rece...	Human	HEK293 Cells
	PILRA Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 50.1 kDa and the accession number is AAH17812.1.
TMPJ-01267	CDH11 Protein, Human, Recombinant (His) Cadherin 11 Type 2 OB-Cadherin (Osteoblast...	Human	HEK293 Cells
	Cadherin-11 is a type II classical cadherin member of the cadherin superfamily of integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Cadherins interact with themselves in a homophilic manner in connecting cells, and thus contribute to the sorting of heterogeneous cell types. Cadherin-11 contains five cadherin domains and is mainly expressed in the brain. Mature cadherin proteins consists of a large N-terminal extracellular domain, a single membrane-spanning domain, and...
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重组蛋白

TGFBR2 Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-00335

Species: Mouse

Expression System: HEK293 Cells

IL-1R2 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-03079

Species: Mouse

Expression System: HEK293 Cells

VE-Cadherin Protein, Human, Recombinant (His & hFc)

Cat.No: TMPY-01677

Species: Human

Expression System: HEK293 Cells

ACVR2A Protein, Human, Recombinant (His)

Cat.No: TMPY-01744

Species: Human

Expression System: HEK293 Cells

Cadherin 6/CDH6 Protein, Human, Recombinant (His)

Cat.No: TMPY-01050

Species: Human

Expression System: HEK293 Cells

TCPTP Protein, Human, Recombinant

Cat.No: TMPY-03484

Species: Human

Expression System: Baculovirus Insect Cells

N Cadherin Protein, Human, Recombinant (His)

Cat.No: TMPY-01143

Species: Human

Expression System: HEK293 Cells

IL-1R2 Protein, Human, Recombinant (His)

Cat.No: TMPY-01366

Species: Human

Expression System: HEK293 Cells

TrkB Protein, Mouse, Recombinant (His)

Cat.No: TMPY-02231

Species: Mouse

Expression System: HEK293 Cells

CLEC-2 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-00586

Species: Mouse

Expression System: HEK293 Cells

IL-1R2 Protein, Human, Recombinant

Cat.No: TMPY-03481

Species: Human

Expression System: HEK293 Cells

ALK-2/ACVR1 Protein, Human, Recombinant (His)

Cat.No: TMPY-04774

Species: Human

Expression System: Baculovirus Insect Cells

TrkB Protein, Human, Recombinant (His)

Cat.No: TMPY-00751

Species: Human

Expression System: HEK293 Cells

Enterotoxin type C-2 Protein, S. aureus, Recombinant

Cat.No: TMPH-03542

Species: Staphylococcus aureus

Expression System: E. coli

Enterotoxin type C-2 Protein, S. aureus, Recombinant (His & SUMO)

Cat.No: TMPH-03541

Species: Staphylococcus aureus

Expression System: E. coli

Metallo-beta-lactamase type 2 Protein, Serratia marcescens, Recombinant (His & Myc)

Cat.No: TMPH-03488

Species: Serratia marcescens

Expression System: E. coli

CAPN2 Protein, Human, Recombinant (His)

Cat.No: TMPH-01031

Species: Human

Expression System: E. coli

ALK-1 Protein, Human, Recombinant (His)

Cat.No: TMPY-01168

Species: Human

Expression System: HEK293 Cells

CLEC10A Protein, Human, Recombinant (hFc)

Cat.No: TMPY-02971

Species: Human

Expression System: HEK293 Cells

HER2/ERBB2 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00778

Species: Human

Expression System: HEK293 Cells

Metallo-beta-lactamase type 2 Protein, Klebsiella pneumoniae, Recombinant (His)

Cat.No: TMPH-02373

Species: Klebsiella pneumoniae

Expression System: E. coli

CLEC12A/MICL/CLL-1 Protein, Human, Recombinant (His)

Cat.No: TMPY-02092

Species: Human

Expression System: HEK293 Cells

BMPR2 Protein, Human, Recombinant (His)

Cat.No: TMPY-01059

Species: Human

Expression System: HEK293 Cells

Cadherin 8/CDH8 Protein, Rat, Recombinant

Cat.No: TMPY-03681

Species: Rat

Expression System: HEK293 Cells

Cadherin 8/CDH8 Protein, Rat, Recombinant (His)

Cat.No: TMPY-03372

Species: Rat

Expression System: HEK293 Cells

Hemojuvelin Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPY-04045

Species: Cynomolgus

Expression System: Baculovirus Insect Cells

COL5A2 Protein, Human, Recombinant (mFc)

Cat.No: TMPY-03809

Species: Human

Expression System: HEK293 Cells

CDH18 Protein, Rhesus, Recombinant (His)

Cat.No: TMPY-04005

Species: Rhesus

Expression System: HEK293 Cells

Cadherin 8/CDH8 Protein, Human, Recombinant (His)

Cat.No: TMPY-01038

Species: Human

Expression System: HEK293 Cells

MRC2 Protein, Canine, Recombinant (His)

Cat.No: TMPK-00574

Species: Canine

Expression System: HEK293 Cells

TrkB Protein, Rat, Recombinant (hFc)

Cat.No: TMPY-02917

Species: Rat

Expression System: HEK293 Cells

VE-Cadherin Protein, Rat, Recombinant (His)

Cat.No: TMPY-03305

Species: Rat

Expression System: HEK293 Cells

TrkB Protein, Canine, Recombinant (His)

Cat.No: TMPY-03635

Species: Canine

Expression System: HEK293 Cells

TrkB Protein, Rat, Recombinant (His)

Cat.No: TMPY-03162

Species: Rat

Expression System: HEK293 Cells

TrkB Protein, Canine, Recombinant (hFc)

Cat.No: TMPY-00228

Species: Canine

Expression System: HEK293 Cells

ACYP2 Protein, Human, Recombinant (GST)

Cat.No: TMPY-02298

Species: Human

Expression System: E. coli

CDH12 Protein, Human, Recombinant (His)

Cat.No: TMPY-01172

Species: Human

Expression System: HEK293 Cells

ARG2 Protein, Human, Recombinant (His)

Cat.No: TMPJ-01058

Species: Human

Expression System: E. coli

TGFBR2 Protein, Mouse, Recombinant (aa 24-159, hFc)

Cat.No: TMPJ-00334

Species: Mouse

Expression System: HEK293 Cells

AGTR2 Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-02268

Species: Human

Expression System: E. coli

TGFBR2 Protein, Mouse, Recombinant (aa 24-184, hFc)

Cat.No: TMPJ-00333

Species: Mouse

Expression System: HEK293 Cells

EPhA2 Protein, Cynomolgus, Recombinant (hFc)

Cat.No: TMPK-00980

Species: Cynomolgus

Expression System: HEK293 Cells

EPhA2 Protein, Cynomolgus, Recombinant (His & Avi)

Cat.No: TMPK-00979

Species: Cynomolgus

Expression System: HEK293 Cells

Cadherin 6/CDH6 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPY-05347

Species: Cynomolgus

Expression System: HEK293 Cells

Cadherin 6/CDH6 Protein, Rat, Recombinant (His)

Cat.No: TMPY-00311

Species: Rat

Expression System: HEK293 Cells

CLEC2D Protein, Rat, Recombinant (hFc)

Cat.No: TMPY-04040

Species: Rat

Expression System: HEK293 Cells

EphB2 Protein, Human, Recombinant (hFc)

Cat.No: TMPJ-00424

Species: Human

Expression System: HEK293 Cells

IL-1R2 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-03078

Species: Mouse

Expression System: HEK293 Cells

PILRA Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00574

Species: Human

Expression System: HEK293 Cells

CDH11 Protein, Human, Recombinant (His)

Cat.No: TMPJ-01267

Species: Human

Expression System: HEK293 Cells

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Cat. No.	Product Name	Target	Signaling Pathways
T14687	Deucravacitinib BMS-986165	Tyrosine Kinases; JAK; IFNAR; Interleukin	Angiogenesis; Chromatin/Epigenetic; Immunology/Inflammation; JAK/STAT signaling; Stem Cells; Tyrosine Kinase/Adaptors
	Deucravacitinib (BMS-986165) 是一种高选择性、口服生物可利用的变构 TYK2 抑制剂，用于治疗自身免疫性疾病。它通过稳定调节 JH2 结构域来阻断受体介导的 Tyk2 激活，可抑制IL-12/23和 I 型IFN 途径。它选择性结合 TYK2 假激酶 (JH2) 结构域，IC50为1.0 nM。
T31109	CTP-499
	CTP499, a selective PDE inhibitor, and the deuterium-containing agent is an HDX analogue and a metabolite of hexantheobromine that slows the progression of type 2 diabetic nephropathy in patients with macroalbuminuria.
T19548	Repaglinide D5 AG-EE 623ZW D5,瑞格列奈 D5	Others	Others
	Repaglinide D5 is deuterium labeled Repaglinide. Repaglinide is an insulin secretagogue for treatment type-2 diabetes mellitus.
T13137	TGFβRI-IN-1	TGF-beta/Smad	Stem Cells
	TGFβRI-IN-1 is an oral active and selective inhibitor of TGFβ receptor type I (TGFβRI) kinase(IC50 values of 2 nM and 7.6 μM for TGFβRI and TGFβRII, respectively ).
T70394	Deucravacitinib HCl
	Deucravacitinib HCl is a Highly Potent and Selective Allosteric Inhibitor of TYK2. BMS-986165 Blocks Il-12, IL-23 and type I Interferon Signaling and Provides for Robust Efficacy in Preclinical Models of Inflammatory Bowel Disease. MS-986165 potently binds to the Tyk2 pseudokinase domain (Ki = 0.02 nM), and is highly selective against a panel of 265 kinases and pseudokinases. The compound potently inhibited IL-23-, IL-12-, and Type I interferon-driven cellular signaling and transcriptional resp...
T73716	Miglustat-d9 HCl
	Miglustat-d9 (hydrochloride)为Miglustat (hydrochloride)的氘代物，属于葡萄糖神经酰胺合成酶抑制剂，主要用于治疗I型戈谢病。
TMID-0043	Sildenafil-d8
	Sildenafil-d8 是 Sildenafil 的氘代化合物。Sildenafil 的 CAS 号为 139755-83-2。Sildenafil 是一种磷酸二酯酶 5 抑制剂，IC50为 5.22 nM。
TMID-0210	Sildenafil-13C-d3
	Sildenafil-13C-d3 是 Sildenafil 的 13C 和氘代化合物。Sildenafil 的 CAS 号为 139755-83-2。Sildenafil 是一种磷酸二酯酶 5 抑制剂，IC50为 5.22 nM。
TMIJ-0013	Acyclovir-d4
	Acyclovir-d4 是 Acyclovir 的氘代化合物。Acyclovir 的 CAS 号为 59277-89-3。Acyclovir是鸟嘌呤类似物和具有口服活性的抗病毒剂。它对HSV-1(IC50为 0.85 μM)，HSV-2(IC50为 0.86 μM) 和水痘带状疱疹病毒有活性。
T71288	Phenylbutazone-d9
	Phenylbutazone-d9 is intended for use as an internal standard for the quantification of phenylbutazone by GC- or LC-MS. Phenylbutazone is a non-steroidal anti-inflammatory drug and an inhibitor of the peroxidase activity of COX (IC50 = ~100 µM in the presence of hydrogen peroxide). It also inhibits prostaglandin I synthase (IC50 = ~25 µM in the presence of hydrogen peroxide). Phenylbutazone (2 mg/kg) reduces increases in type II collagen levels in the inflamed joints of an equine model of LPS-in...
T35775	HT-2 Toxin-13C22 HT-2 Toxin-13C22
	HT-2 toxin-13C22is intended for use as an internal standard for the quantification of HT-2 toxin by GC- or LC-MS. HT-2 toxin is a type A trichothecene mycotoxin and an active, deacetylated metabolite of the trichothecene mycotoxin T-2 toxin .1,2Like T-2 toxin, HT-2 toxin inhibits protein synthesis and cell proliferation in plants.2HT-2 toxin also reduces viability of HepG2, A549, HEp-2, Caco-2, A-204, U937, Jurkat, and RPMI-8226 cancer cells with IC50values ranging from 3.1 to 23 ng/ml and human...
T36055	Nitisinone-13C6 Nitisinone-13C6
	Nitisinone-13C6is intended for use as an internal standard for the quantification of nitisinone by GC- or LC-MS. Nitisinone is an inhibitor of 4-hydroxyphenylpyruvate dioxygenase (HPPD), which converts 4-hydroxyphenylpyruvate (HPPA) to homogentisate in the tyrosine catabolic pathway.1Nitisinone increases urinary levels of HPPA and 4-hydroxyphenyllactate (HPLA) in rats when administered at a dose of 10 mg/kg. Nitisinone (3 mg/kg) prevents the neonatal lethality of fumarylacetoacetate hydrolase (F...
T35790	Palmitic acid-1,2,3,4-13C4 Palmitic Acid-13C (C1, C2, C3, and C4 labeled)
	Palmitic acid-13C (C1, C2, C3, and C4 labeled) is intended for use as an internal standard for the quantification of palmitic acid by GC- or LC-MS. Palmitic acid is a common 16-carbon saturated fat that represents 10-20% of human dietary fat intake and comprises approximately 25 and 65% of human total plasma lipids and saturated fatty acids, respectively.1,2Acylation of palmitic acid to proteins facilitates anchoring of membrane-bound proteins to the lipid bilayer and trafficking of intracellula...
T37847	Zonisamide-13C2,15N Zonisamide-13C2,15N
	Zonisamide-13C2,15N is intended for use as an internal standard for the quantification of zonisamide by GC- or LC-MS. Zonisamide is an antiepileptic agent.1 It selectively inhibits the repeated firing of sodium channels (IC50 = 2 μg/ml) in mouse embryo spinal cord neurons and inhibits spontaneous channel firing when used at concentrations greater than 10 μg/ml.2 In rat cerebral cortex neurons, zonisamide (1-1,000 μM) inhibits T-type calcium channels with a maximum reduction of 60% of the calcium...

同位素标记化合物

Deucravacitinib

Cat.No: T14687

Synonym: BMS-986165

Target: Tyrosine Kinases, JAK, IFNAR, Interleukin

Cat.No: T31109

Cat.No: T19548

Synonym: AG-EE 623ZW D5,瑞格列奈 D5

Target: Others

Cat.No: T13137

Target: TGF-beta/Smad

Deucravacitinib HCl

Cat.No: T70394

Miglustat-d9 HCl

Cat.No: T73716

Cat.No: TMID-0043

Sildenafil-13C-d3

Cat.No: TMID-0210

Cat.No: TMIJ-0013

Phenylbutazone-d9

Cat.No: T71288

HT-2 Toxin-13C22

Cat.No: T35775

Synonym: HT-2 Toxin-13C22

Nitisinone-13C6

Cat.No: T36055

Synonym: Nitisinone-13C6

Palmitic acid-1,2,3,4-13C4

Cat.No: T35790

Synonym: Palmitic Acid-13C (C1, C2, C3, and C4 labeled)

Zonisamide-13C2,15N

Cat.No: T37847

Synonym: Zonisamide-13C2,15N

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