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IRE1α kinase-IN-2
产品编号 T38841Cas号 1414938-21-8
别名 IRE1α kinase-IN-2
IRE1α kinase-IN-2 is a highly potent inhibitor of IRE1α kinase, demonstrating an EC50 of 0.82 μM. It effectively impedes IRE1α kinase autophosphorylation with an IC50 of 3.12 μM. Additionally, IRE1α kinase-IN-2 effectively inhibits the splicing of XBP1 mRNA in wild-type cell lines.
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IRE1α kinase-IN-2
产品编号 T38841 别名 IRE1α kinase-IN-2Cas号 1414938-21-8
IRE1α kinase-IN-2 is a highly potent inhibitor of IRE1α kinase, demonstrating an EC50 of 0.82 μM. It effectively impedes IRE1α kinase autophosphorylation with an IC50 of 3.12 μM. Additionally, IRE1α kinase-IN-2 effectively inhibits the splicing of XBP1 mRNA in wild-type cell lines.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 2 mg | ¥ 3,850 | 5日内发货 | |
| 5 mg | ¥ 4,570 | 5日内发货 | |
| 25 mg | ¥ 19,100 | 6-8周 | |
| 50 mg | ¥ 24,900 | 6-8周 | |
| 100 mg | ¥ 39,900 | 6-8周 |
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产品介绍
生物活性
化学信息
| 产品描述 | IRE1α kinase-IN-2 is a highly potent inhibitor of IRE1α kinase, demonstrating an EC50 of 0.82 μM. It effectively impedes IRE1α kinase autophosphorylation with an IC50 of 3.12 μM. Additionally, IRE1α kinase-IN-2 effectively inhibits the splicing of XBP1 mRNA in wild-type cell lines. |
| 体外活性 | IRE1α kinase-IN-2 (compound 3) inhibits XBP1 mRNA splicing, even during ER stress[1]. |
| 别名 | IRE1α kinase-IN-2 |
| 分子量 | 504.517 |
| 分子式 | C27H23F3N6O |
| CAS No. | 1414938-21-8 |
储存&溶解度
| 存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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体内实验配液计算器
请在以下方框中输入您的动物实验信息后点击计算，可以得到母液配置方法和体内配方的制备方法：
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
剂量转换
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