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NNRT-IN-2 (compound 7w) 是一款高效口服非核苷类逆转录酶抑制剂(NNRTI),能广泛抑制野生型及突变HIV-1菌株。其对HIV-1 逆转录酶的EC50 值为22 nM,显示出对CYP和hERG的不敏感性,确保了良好的安全性和药代动力学属性。
NNRT-IN-2 (compound 7w) 是一款高效口服非核苷类逆转录酶抑制剂(NNRTI),能广泛抑制野生型及突变HIV-1菌株。其对HIV-1 逆转录酶的EC50 值为22 nM,显示出对CYP和hERG的不敏感性,确保了良好的安全性和药代动力学属性。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
10 mg | 询价 | 10-14周 | |
50 mg | 询价 | 10-14周 |
产品描述 | NNRT-IN-2 (compound 7w) is an orally administered non-nucleoside reverse transcriptase inhibitor (NNRTI) that effectively suppresses both wild-type HIV-1 and various mutant strains. It inhibits HIV-1 reverse transcriptase with an EC 50 value of 22 nM. Additionally, NNRT-IN-2 exhibits insensitivity to CYP and hERG, demonstrating favorable safety and pharmacokinetic profiles [1]. |
分子量 | 417.34 |
分子式 | C19H14F3N5O3 |
CAS No. | 2999794-78-2 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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