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Search Results for " synthase "
Targets Recommended: NO Synthase PGE Synthase Fatty Acid Synthase ATPase

514

抑制剂 & 化合物

101

天然产物

2

化合物库

136

重组蛋白

13

同位素标记化合物

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Cat. No. Product Name
L2510 脂代谢化合物库

492 compounds
492 个脂代谢相关的化合物集合,可用于高通量和高内涵筛选;
L8000 干细胞分化化合物库

1197 compounds
1197 种干细胞分化信号通路相关的生物活性小分子化合物的特有集合,可用于高通量、高内涵筛选;

化合物库

脂代谢化合物库
Cat.No: L2510
Compounds: 492
干细胞分化化合物库
Cat.No: L8000
Compounds: 1197
Cat. No. Product Name Target Signaling Pathways
T10404 ATP synthase inhibitor 1

ATPase Membrane transporter/Ion channel
ATP synthase inhibitor 1 是 F1/FO-ATP 合酶复合物 c 亚基的有效抑制剂,抑制线粒体通透性转换孔的开放。
T4380 Ac-CoA Synthase Inhibitor1

ACSS2 inhibitor

RSV; Fatty Acid Synthase Metabolism; Microbiology/Virology
Ac-CoA Synthase Inhibitor1 (ACSS2 inhibitor) 是一种可逆的醋酸盐依赖性乙酰辅酶 A 合成酶 2 抑制剂,IC50为 0.6 µM,可抑制呼吸道合胞病毒。
T27066 Prostaglandin G/H synthase 1 inhibitor

CP74006,CP 74006,2-Amino-N-(4-chlorophenyl)benzamide

Others Others
Prostaglandin G/H synthase 1 inhibitor (CP 74006) 是一种选择性D5D 抑制剂,IC(50)值为20nM。
T61147 Chitin synthase inhibitor 4

Antibiotic Microbiology/Virology
Chitin synthase inhibitor 4 是一种具有抗菌活性的几丁质合成酶(CHS)抑制剂。Chitin synthase inhibitor 4 是一种基于CHS 的化合物,是一种候选的杀菌剂。
T60877 Mtb ATP synthase-IN-1

ATPase Membrane transporter/Ion channel
Mtb ATP synthase-IN-1 是一种可口服的结核分枝杆菌 (Mtb) ATP 合成抑制剂,可用于研究结核分枝杆菌感染。
T39883 Polyketide synthase 13-IN-1

Others Others
Polyketide synthase 13-IN-1 (compound 32) is a polyketide synthase 13 inhibitor.
T39693 Polyketide synthase 13-IN-3

Others Others
Polyketide synthase 13-IN-3 (compound 41) is a potent inhibitor of polyketide synthase 13, demonstrating a minimum inhibitory concentration (MIC) range of 0.0625-0.125 μg/mL against the M. tuberculosis strain H37Rv.
T38168 S.pombe lumazine synthase-IN-1

Others Others
S.pombe lumazine synthase-IN-1 is an inhibitor of lumazine synthases with Ki values of 243 μM and 9.6 μM for Schizosaccharomyces pombe and Mycobacterium tuberculosis lumazine synthases, respectively[1]. [1]. Arindam Talukdar, et al. Discovery and Development of a Small Molecule Library With Lumazine Synthase Inhibitory Activity. J Org Chem. 2009 Aug 7;74(15):5123-34.
T40945 Phospho-Glycogen Synthase Peptide-2(substrate)

Phospho-Glycogen Synthase Peptide-2, a substrate for glycogen synthase kinase-3 (GSK-3), serves as a peptide substrate effective in the affinity purification of protein-serine kinases.
T75397 Hyaluronan synthase (PmHAS)

Others Others
Hyaluronan synthase (PmHAS)为膜蛋白,依赖Mg+2及两种糖-UDP底物(GlcUA-UDP与GlcNAc-UDP)合成HA链。该酶负责透明质酸(HA)的生物合成。
T62701 Dihydropteroate synthase-IN-1

Others Others
Dihydropteroate synthase-IN-1 (compound 5g) 是一种dihydropteroate synthase (DHPS) 的有效抑制剂,对细胞色素 P450 具有抑制作用。Dihydropteroate synthase-IN-1 具有抗微生物活性和抗真菌作用。Dihydropteroate synthase-IN-1 能够用作放射诊断影像材料。
T62738 Chitin synthase inhibitor 6

Others Others
Chitin synthase inhibitor 6 (compound 9b) 是一种 chitin synthase (CHS) 的有效抑制剂 (IC50: 0.21 mM)。Chitin synthase inhibitor 6 对耐药真菌表现出广谱抗真菌效果,能够用于研究真菌感染。
T62246 Chitin synthase inhibitor 8

Others Others
Chitin synthase inhibitor 8 是一种 chitin synthase (CHS) 抑制剂,具有广谱抗真菌作用,能够用于真菌感染相关研究。
T62664 Glucosylceramide synthase-IN-2

Others Others
Glucosylceramide synthase-IN-2 (compound T-690) 是一种有效的、具有血脑屏障通透性的、口服具有活力的 glucosylceramide synthase (GCS) 抑制剂,作用于人 GCS (IC50: 15 nM) 和小鼠 GCS (IC50: 190 nM)。Glucosylceramide synthase-IN-2 能够非竞争性抑制 C8 神经酰胺和 UDP 葡萄糖。Glucosylceramide synthase-IN-2 能够用于研究戈谢病。
T63353 Chitin synthase inhibitor 11

Others Others
Chitin synthase inhibitor 11 是一种高效的几丁质合酶 (CHS) 抑制剂,能够明显抑制 CHS 的活性 (IC50: 0.10 mM),具有广谱体外抑菌作用。Chitin synthase inhibitor 11 能够用于研究侵袭性真菌感染 (IFIs)。
T81109 Squalene synthase-IN-1

Others Others
Squalene synthase-IN-1(compound 1)是一种通过抑制Squalene Synthase来发挥降血脂作用的有效药物。该化合物也展现了卓越的抗氧化和抗炎特性,能显著降低葡萄糖水平和氧化应激,且不引起毒性。
T62068 Chitin synthase inhibitor 1

Others Others
Chitin synthase inhibitor 1 是有效的、选择性的几丁质合酶 (CHS) 抑制剂,IC50值为0.12 mM。Chitin synthase inhibitor 1 强效抑制耐药真菌变体。
T63392 Chitin synthase inhibitor 5

Others Others
Chitin synthase inhibitor 5 是一种几丁质合成酶的抑制剂 (IC50: 0.14 mM)。Chitin synthase inhibitor 5 表现出广谱的真菌抗活性,能够较好的抑制白色念珠菌、黄曲霉、烟毒念珠菌和新生念珠菌,能够用于研究真菌。
T62739 Chitin synthase inhibitor 9

Others Others
Chitin synthase inhibitor 9 是一种几丁质合成酶 (chitin synthase, CHS) 抑制剂,表现出广谱抗真菌效果。Chitin synthase inhibitor 9 能够用于进行真菌感染相关研究。
T78886 Chitin synthase inhibitor 14

Others Others
Chitin synthase inhibitor 14 (compound 4n),一种CHS抑制剂,展现出优异的抗真菌活性和对耐药真菌变异的有效抗性。
T74956 Chitin synthase inhibitor 10

Others Others
Chitin synthase inhibitor 10为一种高效的几丁质合酶(CHS)抑制剂,具有0.11 mM的IC50,表现出显著的CHS抑制活性。作为抗真菌剂,该化合物对包括C. albicans和C. neoformans在内的耐药真菌变体有效,适合用于侵袭性真菌感染(IFI)研究。
T62475 Chitin synthase inhibitor 7

Others Others
Chitin synthase inhibitor 7 (compound 9c) 是一种 chitin synthase (CHS) 的有效抑制剂 (IC50: 0.37 nM)。Chitin synthase inhibitor 7 对耐药真菌具有广谱抗真菌作用。Chitin synthase inhibitor 7 能够用于研究真菌感染。
T79481 Chitin synthase inhibitor 13

Others Others
Chitin synthase inhibitor 13 (compound 12g) 为非竞争性几丁质合酶抑制剂,其IC50为106.7 μM,展现出广谱抗真菌活性。
T61649 ATP synthase inhibitor 2

Others Others
ATP synthase inhibitor2 是一个铜绿假单胞菌 (PA)ATP synthase 抑制剂 (IC50=10 μg/mL),在 128 μg/mL 时可完全抑制铜绿假单胞菌 (PA) 的 ATP 合成活性。
T61398 Chitin synthase inhibitor 3

Others Others
Chitin synthase inhibitor 3 (compound 2d) 是一种高效的chitin synthase抑制剂,具有0.16 mM的IC50值,并对candida albicans显示出1 μg/mL的MIC,表现出抗真菌活性。
T63077 Chitin synthase inhibitor 12

Others Others
Chitin synthase inhibitor 12 是一种几丁质合酶 (CHS) 抑制剂,具有优异的 CHS 抑制作用 (IC50: 0.16 mM)。Chitin synthase inhibitor 12 也是一种广谱抗真菌剂,对耐药真菌变体(如 C. albicans、C. neoformans)具有抗性。Chitin synthase inhibitor 12 能够用于研究侵袭性真菌感染 (IFIs)。
T62898 Glucosylceramide synthase-IN-1

Others Others
Glucosylceramide synthase-IN-1 (T-036) 是一种有效的、口服具有活力的、具有血脑屏障通透性的 glucosylceramide synthase (GCS) 抑制剂,作用于人 GCS (IC50: 31 nM) 和小鼠 GCS (IC50: 51 nM)。Glucosylceramide synthase-IN-1 能够用于研究戈谢病。
T61632 Glucosylceramide synthase-IN-3

Others Others
Glucosylceramide synthase-IN-3 (compound BZ1) is a highly potent, brain-penetrant, and orally active inhibitor of glucosylceramide synthase (GCS), exhibiting an IC50 value of 16 nM for human GCS. This compound, designated as Glucosylceramide synthase-IN-3, finds potential applications in Gaucher's disease research [1] [2].
T61188 Chitin synthase inhibitor 2

Others Others
Chitin synthase inhibitor 2 (compound 2b) is a highly potent inhibitor of chitin synthase, with an IC50 value of 0.09 mM and a K i value of 0.12 mM. This compound exhibits antimicrobial activities in vitro and demonstrates synergistic or additive effects when combined with fluconazole or polyoxin B [1].
TP2195 Nitric Oxide Synthase (599-613) Blocking Peptide, Bovine Endothelial Cell

Others Others
Nitric Oxide Synthase (599-613) Blocking Peptide, Bovine Endothelial Cell (Ac-Pro-Tyr-Asn-Ser-Ser-Pro-Arg-Pro-Glu-Gln-His-Lys-Ser-Tyr-Lys-Cys) is a peptide that inhibits the function of NOSs as a result it blocks the production of NO. Because of the invol
T1866 AT-56

Others; PGE Synthase Immunology/Inflammation; Others
AT56 是口服有活性的脂钙蛋白型前列腺素 D 合酶 (L-PGDS) 选择性抑制剂,其IC50=95 μM,Ki=75 μM。它能够特异性地抑制L-PGDS 催化的 PGD2介导的嗜睡或疼痛反应。
T9987 GSK3-IN-1

GSK-3 PI3K/Akt/mTOR signaling; Stem Cells
GSK3-IN-1是一种 GSK3B-糖原合酶激酶3β抑制剂。
T61598 Polyketide synthase 13-IN-2

Others Others
Polyketide synthase 13-IN-2 (comp 42) is a potent inhibitor of polyketide synthase 13 in Mycobacterium tuberculosis. It demonstrates a minimum inhibitory concentration (MIC) of 0.25 μg/mL [1].
T79004 ATP synthase inhibitor 2 TFA

Others Others
ATP synthase inhibitor2 (Compound 22) TFA 为针对铜绿假单胞菌 (PA) ATP synthase 的抑制剂,具IC50值为10 μg/mL,在浓度达到128 μg/mL 时能够全面阻断铜绿假单胞菌 (PA) ATP的合成活性。
T2681 hPGDS-IN-1

PGE Synthase Immunology/Inflammation
hPGDS-IN-1是 hPGDS 抑制剂,使用荧光偏振检测或通过 EIA 法测得的 IC50值为12 nM。
T1965 Bikinin

Abrasin

Others; GSK-3 Others; PI3K/Akt/mTOR signaling; Stem Cells
Bikinin (Abrasin) 是一种非甾体类的,ATP 竞争性的,植物性 GSK-3/Shaggy-like kinases 抑制剂,可激活 BR 信号通路。
T1741 AZD1080

GSK-3 PI3K/Akt/mTOR signaling; Stem Cells
AZD1080 是一种选择性GSK3抑制剂。它抑制重组人GSK3α和GSK3β,pKi(IC50) 分别为 8.2 (6.9 nM) 和 7.5 (31 nM)。
T10202 A 1070722

GSK-3 PI3K/Akt/mTOR signaling; Stem Cells
A 1070722 是高效的糖原合成酶激酶 3 (GSK-3)选择性抑制剂,与 GSK-3α 和 GSK-3β 结合的Ki 为 0.6 nM。A 1070722 可以穿透血脑屏障并在脑区积聚,具有作为PET 放射性跟踪剂定量测定脑部 GSK-3的潜力。
T61784 GlcN-6-P Synthase-IN-1

Others Others
GlcN-6-P Synthase-IN-1 (Compound 4d) is a potent inhibitor of Glucosamine-6-phosphate (GlcN-6-P) synthase, with an IC50 of 3.47 μM. This compound demonstrates remarkable antimicrobial activity and exhibits excellent penetration in the central nervous system. Additionally, GlcN-6-P Synthase-IN-1 is capable of inhibiting cytochrome P450, specifically the CYP3A4 isoform [1].
T2166 TWS119

GSK-3; Autophagy Autophagy; PI3K/Akt/mTOR signaling; Stem Cells
TWS119 是一种GSK-3β特异性抑制剂,IC50值为 30 nM,它可激活 wnt/β-catenin 信号通路,能够诱导神经元分化。
T5956 VP3.15 dihydrobromide

GSK-3; PDE Metabolism; PI3K/Akt/mTOR signaling; Stem Cells
VP3.15 dihydrobromide 是一种口服具有活力的、高效的、CNS 可渗透的PDE7-GSK3双重抑制剂,对 PDE7 和 GSK3 作用的IC50值分别为 1.59 μM 和 0.88 μM。它具有神经保护和神经修复作用,可用于研究多发性硬化症 (MS) 潜在的抗炎和促髓鞘再生联合。
T3077 SB 216763

SB216763

GSK-3; Autophagy Autophagy; PI3K/Akt/mTOR signaling; Stem Cells
SB 216763 (SB216763) 是一种选择性和ATP 竞争性的GSK-3α/β抑制剂,IC50为34.3 nM。
T2261 IM-12

IM 12

GSK-3 PI3K/Akt/mTOR signaling; Stem Cells
IM-12 是一种 GSK-3β的抑制剂,其 IC50=53 nM,可提高 Wnt 信号传导。
T1957 AZD2858

GSK-3 PI3K/Akt/mTOR signaling; Stem Cells
AZD2858 是具有口服活性的GSK-3抑制剂,可以抑制 GSK-3α (IC50:0.9 nM) 和 GSK-3β (IC50:5 nM) 的活性,可用于骨折愈合的研究。
T5843L (S)-Flurbiprofen

esflurbiprofen,(S)-氟比洛芬

COX; PGE Synthase Immunology/Inflammation; Neuroscience
Esflurbiprofen 是 Flurbiprofen 的活性对映体,是 COX-1 和 COX-2 的抑制剂,对 COX-1和 COX-2的 IC50分别为0.48 和 0.47 μM。
T9213 G140

cGAS Immunology/Inflammation
G140 是选择性环状GMP-AMP 合酶抑制剂,具有抗炎活性,对 h-cGAS 和 m-cGAS 的IC50值分别为 14.0 和 442 nM。
T14066 9-ING-41

Apoptosis; GSK-3; Autophagy Apoptosis; Autophagy; PI3K/Akt/mTOR signaling; Stem Cells
9-ING-41 是基于马来酰亚胺的 ATP 竞争性和选择性的糖原合酶激酶-3β 抑制剂,IC50为 0.71 μM。它显著导致癌细胞的细胞周期停滞,自噬和凋亡,具有增强化疗药物抗肿瘤作用的潜力,有抗癌活性。
T15373 Gboxin

ATPase; Mitochondrial Metabolism Membrane transporter/Ion channel; Metabolism
Gboxin 是一种氧化磷酸化抑制剂,可靶向抑制胶质母细胞瘤生长,还抑制 F0F1 ATP 合成,具有抗肿瘤活性。
T1755 LY2090314

GSK-3 PI3K/Akt/mTOR signaling; Stem Cells
LY2090314 是GSK-3抑制剂,抑制 GSK-3α (IC50:1.5 nM) 和 GSK-3β (IC50:0.9 nM)。
T9611 PF-04802367

GSK-3 PI3K/Akt/mTOR signaling; Stem Cells
PF-04802367是 GSK-3高选择性抑制剂,对 GSK-3β酶的 IC50为 2.1 nM。它抑制两种 GSK-3 亚型(GSK-3α和GSK-3β)效果差不多,IC50值分别为 10.0 和 9.0 nM。它具有理想的中枢神经系统特性和效力。

化合物

ATP synthase inhibitor 1
Cat.No: T10404
Synonym:
Target: ATPase
Ac-CoA Synthase Inhibitor1
Cat.No: T4380
Synonym: ACSS2 inhibitor
Target: RSV, Fatty Acid Synthase
Prostaglandin G/H synthase 1 inhibitor
Cat.No: T27066
Synonym: CP74006,CP 74006,2-Amino-N-(4-chlorophenyl)benzamide
Target: Others
Chitin synthase inhibitor 4
Cat.No: T61147
Synonym:
Target: Antibiotic
Mtb ATP synthase-IN-1
Cat.No: T60877
Synonym:
Target: ATPase
Polyketide synthase 13-IN-1
Cat.No: T39883
Synonym:
Target: Others
Polyketide synthase 13-IN-3
Cat.No: T39693
Synonym:
Target: Others
S.pombe lumazine synthase-IN-1
Cat.No: T38168
Synonym:
Target: Others
Phospho-Glycogen Synthase Peptide-2(substrate)
Cat.No: T40945
Synonym:
Target:
Hyaluronan synthase (PmHAS)
Cat.No: T75397
Synonym:
Target: Others
Dihydropteroate synthase-IN-1
Cat.No: T62701
Synonym:
Target: Others
Chitin synthase inhibitor 6
Cat.No: T62738
Synonym:
Target: Others
Chitin synthase inhibitor 8
Cat.No: T62246
Synonym:
Target: Others
Glucosylceramide synthase-IN-2
Cat.No: T62664
Synonym:
Target: Others
Chitin synthase inhibitor 11
Cat.No: T63353
Synonym:
Target: Others
Squalene synthase-IN-1
Cat.No: T81109
Synonym:
Target: Others
Chitin synthase inhibitor 1
Cat.No: T62068
Synonym:
Target: Others
Chitin synthase inhibitor 5
Cat.No: T63392
Synonym:
Target: Others
Chitin synthase inhibitor 9
Cat.No: T62739
Synonym:
Target: Others
Chitin synthase inhibitor 14
Cat.No: T78886
Synonym:
Target: Others
Chitin synthase inhibitor 10
Cat.No: T74956
Synonym:
Target: Others
Chitin synthase inhibitor 7
Cat.No: T62475
Synonym:
Target: Others
Chitin synthase inhibitor 13
Cat.No: T79481
Synonym:
Target: Others
ATP synthase inhibitor 2
Cat.No: T61649
Synonym:
Target: Others
Chitin synthase inhibitor 3
Cat.No: T61398
Synonym:
Target: Others
Chitin synthase inhibitor 12
Cat.No: T63077
Synonym:
Target: Others
Glucosylceramide synthase-IN-1
Cat.No: T62898
Synonym:
Target: Others
Glucosylceramide synthase-IN-3
Cat.No: T61632
Synonym:
Target: Others
Chitin synthase inhibitor 2
Cat.No: T61188
Synonym:
Target: Others
Nitric Oxide Synthase (599-613) Blocking Peptide, Bovine Endothelial Cell
Cat.No: TP2195
Synonym:
Target: Others
AT-56
Cat.No: T1866
Synonym:
Target: Others, PGE Synthase
GSK3-IN-1
Cat.No: T9987
Synonym:
Target: GSK-3
Polyketide synthase 13-IN-2
Cat.No: T61598
Synonym:
Target: Others
ATP synthase inhibitor 2 TFA
Cat.No: T79004
Synonym:
Target: Others
hPGDS-IN-1
Cat.No: T2681
Synonym:
Target: PGE Synthase
Bikinin
Cat.No: T1965
Synonym: Abrasin
Target: Others, GSK-3
AZD1080
Cat.No: T1741
Synonym:
Target: GSK-3
A 1070722
Cat.No: T10202
Synonym:
Target: GSK-3
GlcN-6-P Synthase-IN-1
Cat.No: T61784
Synonym:
Target: Others
TWS119
Cat.No: T2166
Synonym:
Target: GSK-3, Autophagy
VP3.15 dihydrobromide
Cat.No: T5956
Synonym:
Target: GSK-3, PDE
SB 216763
Cat.No: T3077
Synonym: SB216763
Target: GSK-3, Autophagy
IM-12
Cat.No: T2261
Synonym: IM 12
Target: GSK-3
AZD2858
Cat.No: T1957
Synonym:
Target: GSK-3
(S)-Flurbiprofen
Cat.No: T5843L
Synonym: esflurbiprofen,(S)-氟比洛芬
Target: COX, PGE Synthase
G140
Cat.No: T9213
Synonym:
Target: cGAS
9-ING-41
Cat.No: T14066
Synonym:
Target: Apoptosis, GSK-3, Autophagy
Gboxin
Cat.No: T15373
Synonym:
Target: ATPase, Mitochondrial Metabolism
LY2090314
Cat.No: T1755
Synonym:
Target: GSK-3
PF-04802367
Cat.No: T9611
Synonym:
Target: GSK-3
Cat. No. Product Name Target Signaling Pathways
T2S2335 Dehydroevodiamine

DHED,去氢吴茱萸碱

Others; NF-κB; COX; PGE Synthase; NO Synthase Immunology/Inflammation; Neuroscience; NF-κB; Others
Dehydroevodiamine (DHED) 是从吴茱萸中分离出的一种喹唑啉生物碱,可抑制 LPS 诱导的小鼠巨噬细胞中iNOS、COX-2、PGE2和NF-κB 的表达,对豚鼠心室肌细胞具有抗心律失常作用。
TQ0260 Cerulenin

Antibiotic; Antifungal; Fatty Acid Synthase Metabolism; Microbiology/Virology
Cerulenin 是广泛使用的天然脂肪酸合成酶抑制剂。它是由真菌Cephalosporium caeruleus 产生的。它抑制拓扑异构酶I 催化活性并增强 SN-38 诱导的细胞凋亡。它具有抗真菌和抗肿瘤活性。
T5681 ETHYL CAFFEATE

咖啡酸乙酯,ETHYL 3,4-DIHYDROXYCINNAMATE

NF-κB; COX; PGE Synthase; NO Synthase Immunology/Inflammation; Neuroscience; NF-κB
Ethyl Caffeate (ETHYL 3,4-DIHYDROXYCINNAMATE) 是从鬼针草分离的一种酚类天然产物,在体外或在小鼠皮肤中抑制NF-κB 活化及其下游炎症介质的诱导型一氧化氮合酶、环氧合酶 2 和前列腺素 E2。
TQ0301 Kuwanon A

NO Synthase Immunology/Inflammation
Kuwanon A 抑制一氧化氮的产生 (IC50: 10.5 μM)。Kuwanon A 是从桑树 (Morus alba L.) 中分离出来的黄酮衍生物。
T6S1665 Irisflorentin

Others; NO Synthase Immunology/Inflammation; Others
Irisflorentin 是天然存在的异黄酮,是大量存在于 Rhizoma Belamcandae 中的活性成分。它明显抑制了诱导型一氧化氮合酶的转录和翻译以及 NO 产生。
T4S0227 Sinensetin

Pedalitin permethyl ether,甜橙素

TNF; PGE Synthase Apoptosis; Immunology/Inflammation
Sinensetin (Pedalitin permethyl ether) 是从水果中发现的一种甲基化黄酮,有很强的抗血管和抗炎症的能力。
T6S2023 Harpagoside

Others; COX; NO Synthase Immunology/Inflammation; Neuroscience; Others
Harpagoside 是从爪钩草中分离出来的一种天然产物,可抑制COX-1和COX-2活性,并抑制 NO 的产生。
T5727 CAFESTOL

咖啡醇,咖啡油醇

ERK; NF-κB; COX; PGE Synthase Immunology/Inflammation; MAPK; Neuroscience; NF-κB
Cafestol 是咖啡特有的一种二萜,可靶向 AP-1 抑制ERK,有化学预防、抗肿瘤、保肝、抗氧化和抗炎作用。它通过抑制NF-kB 活化途径强烈的抑制 PGE2的产生,还抑制 LGE 激活的 RAW264.7 细胞中的PGE2产生和环氧合酶(COX-2)的 mRNA 表达。
T2824 Pedunculoside

Others; Fatty Acid Synthase Metabolism; Others
Pedunculoside 是从 Ilex rotunda Thunb 中提取的,通过对脂质形成和脂肪酸 β-氧化的调节而发挥降脂作用。
T7682 Asymmetric dimethylarginine

Endogenous Metabolite; NO Synthase; NOD Immunology/Inflammation; Metabolism; NF-κB
Asymmetric dimethylarginine 是内源性一氧化氮合成酶抑制剂,可以作为内皮功能障碍的标志。
T2S0765 Epibetulinic acid

NO Synthase; Prostaglandin Receptor GPCR/G Protein; Immunology/Inflammation
Epibetulinic acid 对细菌内毒素刺激的小鼠巨噬细胞 (RAW 264.7) 中 NO 和前列腺素 E(2) 的产生具有有效的抑制作用,IC50分别为 0.7 和 0.6 μM,具有抗炎活性。
T3847 Asperuloside

Asperulosid,车叶草苷

Others; NO Synthase Immunology/Inflammation; Others
Asperuloside (Asperulosid) 是一种来源于蛇舌草的环烯醚萜,具有抗炎作用。它可抑制诱导型一氧化氮合酶,抑制 NF-κB 和 MAPK 信号通路。
T5838 L-Canavanine sulfate

NO Synthase; NOD Immunology/Inflammation; NF-κB
L-Canavanine sulfate 是一种诱导型 NO 合酶的选择性抑制剂。
TN6772 Malabaricone C

Others Others
Malabaricone C 是天然的鞘磷脂合成酶抑制剂,对 SMS 1 和 SMS 2 的IC50分别为 3 和 1.5 μM。
T5S0285 Cistanoside A

肉苁蓉苷 A,肉苁蓉苷A

Others Others
Cistanoside A 是一种肉苁蓉中的苯丙素类化合物,能够抑制 NO 的聚集,但不影响诱导型一氧化氮合酶 iNOS 的 mRNA 和蛋白水平及其活性。它具有抗炎作用。
T5S0246 Pseudoprotodioscin

山药

Others; Fatty Acid Synthase Metabolism; Others
Pseudoprotodioscin 是一种呋喃葡糖苷,抑制SREBP1/2和microRNA 33a/b 水平,降低胆固醇和甘油三酯合成相关的基因表达。
TJS0387 Desoxyrhaponticin

去氧土大黄苷,Deoxyrhapontin,脱氧土大黄苷,Deoxyrhaponticin

Apoptosis; Fatty Acid Synthase Apoptosis; Metabolism
Desoxyrhaponticin (Deoxyrhaponticin) 是来自西藏营养食品唐古特大黄中的一种二苯乙烯苷。它是脂肪酸合成酶抑制剂,抑制细胞内 FAS 活性,下调人乳腺癌 MCF-7细胞中 FAS 的表达。它是控制糖尿病餐后高血糖的潜在药物。
T4808 Agmatine sulfate

Agmatine sulfate salt,硫酸胍基丁胺

Endogenous Metabolite; NO Synthase; Imidazoline Receptor Immunology/Inflammation; Metabolism; Neuroscience
Agmatine sulfate (Agmatine sulfate salt) 是咪唑啉受体的内源性激动剂和一氧化氮合酶抑制剂。它靶向神经递质系统,离子通道和一氧化氮合成。
T6323 Oligomycin A

MCH 32,寡霉素A

ATPase; Antibiotic; Antifungal Membrane transporter/Ion channel; Microbiology/Virology
Oligomycin A (MCH 32) 属于天然产物,是一种线粒体 F0F1-ATPase 抑制剂 (Ki=1 μM)。Oligomycin A 可以抑制线粒体氧化磷酸化,诱导细胞凋亡。Oligomycin A 具有抗真菌活性。
T7597 6-Biopterin

L-生物喋呤,L-Biopterin

Endogenous Metabolite; NO Synthase; NOD Immunology/Inflammation; Metabolism; NF-κB
6-Biopterin (L-Biopterin) 是一种蝶呤衍生物,是一氧化氮合酶 (NO synthase) 辅因子。
TN2139 Regaloside B

鸦胆子苦醇,王百合苷 B

NOS; COX; NO Synthase Immunology/Inflammation; Neuroscience
Regaloside B 是从麝香百合中分离出来的一种苯丙烷,可抑制iNOS 和COX-2的表达,具有抗炎活性。
T2791 Pectolinarin

柳穿鱼叶苷,大蓟苷

Apoptosis; Others; NO Synthase; Prostaglandin Receptor; Interleukin Apoptosis; GPCR/G Protein; Immunology/Inflammation; Others
Pectolinarin 抑制 IL-6和 IL-8分泌以及 PGE2和 NO 产生,可通过抑制 PI3K/Akt 途径来抑制细胞增殖和炎症反应并诱导凋亡,具有抗炎活性。
T2980 Chondroitin sulfate

Chonsurid,Chondroitin polysulfate,硫酸软骨素

MMP; Others; Endogenous Metabolite; NO Synthase Immunology/Inflammation; Metabolism; Others; Proteases/Proteasome
Chondroitin sulfate (Chonsurid) 是一种糖胺聚糖,被广泛用于骨关节炎的研究。它能够减少炎症介质和凋亡过程,并能够减少炎性细胞因子,iNOS 和MMPs 产生。
T3S0364 L-Arginine

L-精氨酸,L-Arg,(S)-(+)-Arginine

IL Receptor; Endogenous Metabolite; NO Synthase Immunology/Inflammation; Metabolism
L-Arginine (L-Arg) 是内皮型一氧化氮合酶(eNOS) 的底物。L-Arginine 通过阳离子氨基酸转运体家族转运到血管平滑肌细胞,并被代谢成一氧化氮、多胺或 L-脯氨酸。
T3121 Betulin

Trochol,betulinic alcohol,betuline,betulinol,桦木醇,Betulol,白桦脂醇

Apoptosis; Endogenous Metabolite; Lipid; Fatty Acid Synthase Apoptosis; Metabolism
Betulin (betulinol) 是从桦树树皮中分离出来的一种天然三萜,是 SREBP 抑制剂。
T1310 2-Thiouracil

Thiouracil,硫代由雪,Deracil,2-硫脲嘧啶

Thyroid hormone receptor(THR); NO Synthase Endocrinology/Hormones; Immunology/Inflammation
2-Thiouracil (Deracil) 是神经型一氧化氮合酶 (nNOS) 的选择性抑制剂(Ki:20 μM),是一种抗甲状腺化合物,可用作高度特异性的黑色素瘤探测物。
TN1373 α-Humulene

Alpha-caryophyllene,ALPHA-律草烯

TNF; NOS; COX Apoptosis; Immunology/Inflammation; Neuroscience
α-Humulene (Alpha-caryophyllene) 是 Tanacetum vulgareL. 精油的主要成分,显示出抗炎作用,IC50=15±2 μg/mL。它抑制 iNOS 和COX-2表达。
T5684 Ethyl 3,4-dihydroxybenzoate

Apoptosis; Others; Reactive Oxygen Species; HIF/HIF Prolyl-Hydroxylase; NO Synthase; Autophagy Apoptosis; Autophagy; Chromatin/Epigenetic; Immunology/Inflammation; Metabolism; NF-κB; Others
Ethyl 3,4-dihydroxybenzoate 是从花生种子的种皮中发现的脯氨酰羟化酶抑制剂,是一种抗氧化剂。它是胶原蛋白合成抑制剂,具有骨骼保护作用。它通过激活 NO 合酶并产生线粒体 ROS 来保护心肌,可诱导 ESCC 细胞自噬和凋亡。
T7030 anemarsaponin B

知母皂苷B,知母皂苷 B

p38 MAPK; NF-κB; MEK; COX; NO Synthase Immunology/Inflammation; MAPK; Neuroscience; NF-κB
Anemarsaponin B 是一种甾体皂苷,可降低iNOS 和COX-2的蛋白和 mRNA 水平,减少促炎细胞因子的表达和产生。它通过阻断 IκBα 的磷酸化来抑制NF-κB 的 p65 亚基的核转位,还抑制 MAP 激酶激酶 3/6 (MKK3/6) 和混合谱系激酶 3 的磷酸化。
T7786 Tryptanthrin

DNA gyrase DNA Damage/DNA Repair
Tryptanthrin 是一种口服具有活性的细胞内Leukotriene (LT) biosynthesis 抑制剂。 它能够降低大鼠胸膜炎模型中的 LTB4 水平,并抑制人全血中Leukotriene 的形成 (IC50= 10 µM)。
T3322 trans-Chalcone

Chalcone,反-查耳酮,查尔酮,Cinnamophenone,Chalkone

Apoptosis; Others; Antifungal; Fatty Acid Synthase Apoptosis; Metabolism; Microbiology/Virology; Others
trans-Chalcone (Chalkone) 是从 Aronia melanocarpa 果皮中分离出来的一种天然产物,是类黄酮前体的双酚核心结构。它是脂肪酸合酶和 α-淀粉酶的抑制剂,具有抗真菌和抗癌活性。
T3918 Ginsenoside Rb3

人参皂苷 Rb3,Gypenoside IV,人参皂苷Rb3

NF-κB; COX; NO Synthase Immunology/Inflammation; Neuroscience; NF-κB
Ginsenoside Rb3 (Gypenoside IV) 是从三七中提取的一种天然产物。它在 293T 细胞系中抑制 TNFα 诱导的NF-κB 转录活性,IC50为 8.2 μM。它还抑制COX-2和iNOSmRNA 的诱导。
T0983 Penicillamine

青霉胺,d-penicillamin,Dimethyl Cysteine,D-青霉胺,Artamine,D-(-)-Penicillamine

Antibiotic Microbiology/Virology
Penicillamine (Artamine) 是一种 penicillin 的代谢降解产物,是一种螯合剂,可作用于威尔逊氏病。
T4S1173 Agrimol B

仙鹤草酚B,仙鹤草酚 B

Sirtuin; PPAR Chromatin/Epigenetic; DNA Damage/DNA Repair; Metabolism
Agrimol B 是从仙鹤草中分离得到的一种多酚衍生物,可抑制脂肪形成,降低PPARγ的表达,诱导SIRT1易位和表达。
T3779 Crocin II

Crocin 2,西红花苷II,Crocetin gentiobiosylglucosyl ester,藏红花,Tricrocin,Crocin B

Caspase; COX; NO Synthase Apoptosis; Immunology/Inflammation; Neuroscience; Proteases/Proteasome
Crocin II (Crocetin gentiobiosylglucosyl ester) 是从栀子果实中分离出来的一种天然产物,具有抗氧化、抗癌和抗抑郁活性。它抑制 iNOS 和 COX-2的蛋白质和 m-RNA 的表达,还抑制NO 产生,IC50值为 31.1 μM。
T3811 Ginsenoside C-K

20(S)-人参皂苷 C-K,Ginsenoside compound K,Ginsenoside K,人参皂苷 C-K

P450; cell cycle arrest; COX; NO Synthase Cell Cycle/Checkpoint; Immunology/Inflammation; Metabolism; Neuroscience
Ginsenoside C-K (Ginsenoside K) 是 Ginsenoside Rb1 的细菌代谢物,可通过抑制诱生型一氧化氮合酶和COX-2来发挥抗炎作用。它在人肝微粒体中抑制CYP2C9和CYP2A6活性,IC50分别为 32.0±3.6 和 63.6±4.2 μM。
T3805 Prim-O-glucosylcimifugin

升麻苷,Cimifugin beta-D-glucopyranoside,Cimifugin 7-glucoside

TNF; COX; JAK; NO Synthase Angiogenesis; Apoptosis; Chromatin/Epigenetic; Immunology/Inflammation; JAK/STAT signaling; Neuroscience; Stem Cells
Prim-O-glucosylcimifugin (Cimifugin 7-glucoside) 具有强效的抗炎作用。通过调节 JAK2/STAT3 信号传导可抑制iNOS 和COX-2表达。
T3324 Lycorine

Galanthidine,Narcissine,石蒜碱,Amarylline,Belamarine,Licorine,番石榴碱

Apoptosis; Virus Protease; Antibacterial; AChR; Fatty Acid Synthase Apoptosis; Metabolism; Microbiology/Virology; Neuroscience
Lycorine (Narcissine) 是从金眼科植物科中提取的一种天然生物碱。它是一种具有口服活性的SCAP 抑制剂,Kd 值 15.24 nM。它也是黑色素瘤血管生成抑制剂,有用于前列腺癌和代谢疾病的研究潜力。
T3S0401 Piceatannol 3'-O-glucoside

白皮杉醇 3'-O-葡萄糖苷,Piceatannol 3-glycoside,Quzhaqigan,曲札茋苷、白皮杉醇-3'-O-葡萄糖苷

Arginase; NO Synthase Immunology/Inflammation
Piceatannol 3'-O-glucoside (Piceatannol 3-glycoside) 是大黄的一种活性成分,通过抑制精氨酸酶活性激活内皮细胞一氧化氮合酶,抑制Arginase I 和Arginase II,IC50值分别为 11.22 和 11.06 μM。它可增加肺血氧分压,减少肺间质水肿,从而保护肺损伤。
T2758 Madecassic acid

6-Deoxy-L-Galactose,羟基积雪草酸,L-Fucose,Brahmic acid,L-fucopyranose

Others; TNF; COX; NO Synthase; Interleukin Apoptosis; Immunology/Inflammation; Neuroscience; Others
Madecassic acid (L-fucopyranose) 是分离自积雪草的一种天然产物,抑制iNOS、COX-2、TNF-α、IL-1beta 和IL-6,可通过在 RAW 264.7 巨噬细胞中下调NF-κB 激活而具有抗炎作用。
T5S0754 Isoquercetin

3-Glucosylquercetin,Hirsutrin,Isoquercitrin,异槲皮苷,Quercetin 3-o-glucopyranoside,槲皮素-3-葡萄糖苷

NF-κB; Wnt/beta-catenin; NO Synthase Cytoskeletal Signaling; Immunology/Inflammation; NF-κB; Stem Cells
Isoquercetin (3-Glucosylquercetin) 是天然存在的多酚,具有抗氧化,抗增殖和抗炎特性。它通过调节核因子-κB 转录调节系统调节一氧化氮合酶 2 的表达。它通过 Nrf2/ARE 抗氧化剂信号传导途径减轻乙醇诱导的肝毒性,氧化应激和炎症反应。它具有高生物利用度和低毒性,是预防糖尿病妊娠出生缺陷的有希望的候选药物。
T0670 L-Arginine hydrochloride

(S)-(+)-Arginine hydrochloride,左旋精氨酸单盐酸盐,L-Arginine HCl (L-Arg),L-arginine monohydrochloride

Amino Acids and Derivatives; Endogenous Metabolite; NO Synthase Immunology/Inflammation; Metabolism
L-Arginine hydrochloride 为合成一氧化氮的氮供体,是血管扩张剂。
T4S1421 Praeruptorin B

Praeruptorin D,(+)-川白芷内酯

NPC1L1; Fatty Acid Synthase Membrane transporter/Ion channel; Metabolism
Praeruptorin B 是一种固醇调控元件结合蛋白(SREBPs)的抑制剂。
TN1102 Physalin L

酸浆苦味素L,酸浆苦味素 L

Others; NO Synthase Immunology/Inflammation; Others
Physalin L 抑制巨噬细胞中 LPS 诱导的 NO 生成,平均抑制率是 70.97%。它具有抗炎作用。
TN1109 3-O-Acetyl-16α-hydroxydehydrotrametenolic acid

3-O-Acetyl-16 alpha-hydroxydehydrotrametenolic acid,3-O-乙酰基-16Α-羟基松苓新酸

NOS; NO Synthase; Prostaglandin Receptor GPCR/G Protein; Immunology/Inflammation
3-O-Acetyl-16α-hydroxydehydrotrametenolic acid (3-O-Acetyl-16 alpha-hydroxydehydrotrametenolic acid) 是三萜类化合物。它能够作用于 LPS 刺激的 Raw264.7 细胞,减少NO 产生和 iNOS 表达,具有消炎作用。
T7344 SDMA

NG,NG'-Dimethyl-L-arginine,Symmetric dimethylarginine,对称N,N-二甲基精氨酸

Endogenous Metabolite Metabolism
SDMA (Symmetric dimethylarginine) 是一氧化氮 (NO) 合酶的内源性抑制剂。
T9267 Aureobasidin A

Others; Antifungal Microbiology/Virology; Others
Aureobasidin A 是一种环肽和抗真菌抗生素。它是肌醇磷酸神经酰胺合酶 AUR1 的抑制剂。
T12039 Miglustat

N-Butyldeoxynojirimycin,OGT918,美格鲁特,NB-DNJ,N-丙基脱氧野尻霉素

Others Others
Miglustat (NB-DNJ) 是一种葡萄糖神经酰胺合成酶抑制剂,可用于I 型戈谢病。
T5267 N-Acetyl-L-glutamic acid

Ac-L-Glu-OH,N-乙酰-L-谷氨酰胺,N-Acetylglutamic acid

Others; Endogenous Metabolite Metabolism; Others
N-Acetyl-L-glutamic acid (Ac-L-Glu-OH) 是一种 N-Acyl-L-氨基酸,是动物细胞培养基的组成成分,是一种酿酒酵母和人类的代谢物。
T17056 Tetrahydrobiopterin

Sapropterin,BH4,(Rac)-Sapropterin

NOS; Endogenous Metabolite Immunology/Inflammation; Metabolism
Tetrahydrobiopterin (BH4) 是芳香族氨基酸羟化酶的辅因子, 也是一氧化氮合酶 (NOS) 的必需辅因子,可用于研究如高血压、高胆固醇血症、糖尿病等内皮功能障碍。
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天然产物

Dehydroevodiamine
Cat.No: T2S2335
Synonym: DHED,去氢吴茱萸碱
Target: Others, NF-κB, COX, PGE Synthase, NO Synthase
Cerulenin
Cat.No: TQ0260
Synonym:
Target: Antibiotic, Antifungal, Fatty Acid Synthase
ETHYL CAFFEATE
Cat.No: T5681
Synonym: 咖啡酸乙酯,ETHYL 3,4-DIHYDROXYCINNAMATE
Target: NF-κB, COX, PGE Synthase, NO Synthase
Kuwanon A
Cat.No: TQ0301
Synonym:
Target: NO Synthase
Irisflorentin
Cat.No: T6S1665
Synonym:
Target: Others, NO Synthase
Sinensetin
Cat.No: T4S0227
Synonym: Pedalitin permethyl ether,甜橙素
Target: TNF, PGE Synthase
Harpagoside
Cat.No: T6S2023
Synonym:
Target: Others, COX, NO Synthase
CAFESTOL
Cat.No: T5727
Synonym: 咖啡醇,咖啡油醇
Target: ERK, NF-κB, COX, PGE Synthase
Pedunculoside
Cat.No: T2824
Synonym:
Target: Others, Fatty Acid Synthase
Asymmetric dimethylarginine
Cat.No: T7682
Synonym:
Target: Endogenous Metabolite, NO Synthase, NOD
Epibetulinic acid
Cat.No: T2S0765
Synonym:
Target: NO Synthase, Prostaglandin Receptor
Asperuloside
Cat.No: T3847
Synonym: Asperulosid,车叶草苷
Target: Others, NO Synthase
L-Canavanine sulfate
Cat.No: T5838
Synonym:
Target: NO Synthase, NOD
Malabaricone C
Cat.No: TN6772
Synonym:
Target: Others
Cistanoside A
Cat.No: T5S0285
Synonym: 肉苁蓉苷 A,肉苁蓉苷A
Target: Others
Pseudoprotodioscin
Cat.No: T5S0246
Synonym: 山药
Target: Others, Fatty Acid Synthase
Desoxyrhaponticin
Cat.No: TJS0387
Synonym: 去氧土大黄苷,Deoxyrhapontin,脱氧土大黄苷,Deoxyrhaponticin
Target: Apoptosis, Fatty Acid Synthase
Agmatine sulfate
Cat.No: T4808
Synonym: Agmatine sulfate salt,硫酸胍基丁胺
Target: Endogenous Metabolite, NO Synthase, Imidazoline Receptor
Oligomycin A
Cat.No: T6323
Synonym: MCH 32,寡霉素A
Target: ATPase, Antibiotic, Antifungal
6-Biopterin
Cat.No: T7597
Synonym: L-生物喋呤,L-Biopterin
Target: Endogenous Metabolite, NO Synthase, NOD
Regaloside B
Cat.No: TN2139
Synonym: 鸦胆子苦醇,王百合苷 B
Target: NOS, COX, NO Synthase
Pectolinarin
Cat.No: T2791
Synonym: 柳穿鱼叶苷,大蓟苷
Target: Apoptosis, Others, NO Synthase, Prostaglandin Receptor, Interleukin
Chondroitin sulfate
Cat.No: T2980
Synonym: Chonsurid,Chondroitin polysulfate,硫酸软骨素
Target: MMP, Others, Endogenous Metabolite, NO Synthase
L-Arginine
Cat.No: T3S0364
Synonym: L-精氨酸,L-Arg,(S)-(+)-Arginine
Target: IL Receptor, Endogenous Metabolite, NO Synthase
Betulin
Cat.No: T3121
Synonym: Trochol,betulinic alcohol,betuline,betulinol,桦木醇,Betulol,白桦脂醇
Target: Apoptosis, Endogenous Metabolite, Lipid, Fatty Acid Synthase
2-Thiouracil
Cat.No: T1310
Synonym: Thiouracil,硫代由雪,Deracil,2-硫脲嘧啶
Target: Thyroid hormone receptor(THR), NO Synthase
α-Humulene
Cat.No: TN1373
Synonym: Alpha-caryophyllene,ALPHA-律草烯
Target: TNF, NOS, COX
Ethyl 3,4-dihydroxybenzoate
Cat.No: T5684
Synonym:
Target: Apoptosis, Others, Reactive Oxygen Species, HIF/HIF Prolyl-Hydroxylase, NO Synthase, Autophagy
anemarsaponin B
Cat.No: T7030
Synonym: 知母皂苷B,知母皂苷 B
Target: p38 MAPK, NF-κB, MEK, COX, NO Synthase
Tryptanthrin
Cat.No: T7786
Synonym:
Target: DNA gyrase
trans-Chalcone
Cat.No: T3322
Synonym: Chalcone,反-查耳酮,查尔酮,Cinnamophenone,Chalkone
Target: Apoptosis, Others, Antifungal, Fatty Acid Synthase
Ginsenoside Rb3
Cat.No: T3918
Synonym: 人参皂苷 Rb3,Gypenoside IV,人参皂苷Rb3
Target: NF-κB, COX, NO Synthase
Penicillamine
Cat.No: T0983
Synonym: 青霉胺,d-penicillamin,Dimethyl Cysteine,D-青霉胺,Artamine,D-(-)-Penicillamine
Target: Antibiotic
Agrimol B
Cat.No: T4S1173
Synonym: 仙鹤草酚B,仙鹤草酚 B
Target: Sirtuin, PPAR
Crocin II
Cat.No: T3779
Synonym: Crocin 2,西红花苷II,Crocetin gentiobiosylglucosyl ester,藏红花,Tricrocin,Crocin B
Target: Caspase, COX, NO Synthase
Ginsenoside C-K
Cat.No: T3811
Synonym: 20(S)-人参皂苷 C-K,Ginsenoside compound K,Ginsenoside K,人参皂苷 C-K
Target: P450, cell cycle arrest, COX, NO Synthase
Prim-O-glucosylcimifugin
Cat.No: T3805
Synonym: 升麻苷,Cimifugin beta-D-glucopyranoside,Cimifugin 7-glucoside
Target: TNF, COX, JAK, NO Synthase
Lycorine
Cat.No: T3324
Synonym: Galanthidine,Narcissine,石蒜碱,Amarylline,Belamarine,Licorine,番石榴碱
Target: Apoptosis, Virus Protease, Antibacterial, AChR, Fatty Acid Synthase
Piceatannol 3'-O-glucoside
Cat.No: T3S0401
Synonym: 白皮杉醇 3'-O-葡萄糖苷,Piceatannol 3-glycoside,Quzhaqigan,曲札茋苷、白皮杉醇-3'-O-葡萄糖苷
Target: Arginase, NO Synthase
Madecassic acid
Cat.No: T2758
Synonym: 6-Deoxy-L-Galactose,羟基积雪草酸,L-Fucose,Brahmic acid,L-fucopyranose
Target: Others, TNF, COX, NO Synthase, Interleukin
Isoquercetin
Cat.No: T5S0754
Synonym: 3-Glucosylquercetin,Hirsutrin,Isoquercitrin,异槲皮苷,Quercetin 3-o-glucopyranoside,槲皮素-3-葡萄糖苷
Target: NF-κB, Wnt/beta-catenin, NO Synthase
L-Arginine hydrochloride
Cat.No: T0670
Synonym: (S)-(+)-Arginine hydrochloride,左旋精氨酸单盐酸盐,L-Arginine HCl (L-Arg),L-arginine monohydrochloride
Target: Amino Acids and Derivatives, Endogenous Metabolite, NO Synthase
Praeruptorin B
Cat.No: T4S1421
Synonym: Praeruptorin D,(+)-川白芷内酯
Target: NPC1L1, Fatty Acid Synthase
Physalin L
Cat.No: TN1102
Synonym: 酸浆苦味素L,酸浆苦味素 L
Target: Others, NO Synthase
3-O-Acetyl-16α-hydroxydehydrotrametenolic acid
Cat.No: TN1109
Synonym: 3-O-Acetyl-16 alpha-hydroxydehydrotrametenolic acid,3-O-乙酰基-16Α-羟基松苓新酸
Target: NOS, NO Synthase, Prostaglandin Receptor
SDMA
Cat.No: T7344
Synonym: NG,NG'-Dimethyl-L-arginine,Symmetric dimethylarginine,对称N,N-二甲基精氨酸
Target: Endogenous Metabolite
Aureobasidin A
Cat.No: T9267
Synonym:
Target: Others, Antifungal
Miglustat
Cat.No: T12039
Synonym: N-Butyldeoxynojirimycin,OGT918,美格鲁特,NB-DNJ,N-丙基脱氧野尻霉素
Target: Others
N-Acetyl-L-glutamic acid
Cat.No: T5267
Synonym: Ac-L-Glu-OH,N-乙酰-L-谷氨酰胺,N-Acetylglutamic acid
Target: Others, Endogenous Metabolite
Tetrahydrobiopterin
Cat.No: T17056
Synonym: Sapropterin,BH4,(Rac)-Sapropterin
Target: NOS, Endogenous Metabolite
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Cat. No. Product Name Species Expression System
TMPY-03120 Prostaglandin D2 Synthase Protein, Human, Recombinant (His)

PDS,L-PGDS,PGDS,PGDS2,LPGDS,PGD2,prostaglandin D2 syntha...

Human HEK293 Cells
Prostaglandin D2 Synthase Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.1 kDa and the accession number is P41222.
TMPY-04070 Citrate Synthase Protein, Human, Recombinant (His)

citrate synthase

Human Baculovirus Insect Cells
Chondroitin sulphate (CS) glycosaminoglycan chains on cell and extracellular matrix proteoglycans (PGs) can no longer be regarded as merely hydrodynamic space fillers. Overwhelming evidence over recent years indicates that sulphation motif sequences within the CS chain structure are a source of significant biological information to cells and their surrounding environment. CS sulphation motifs have been shown to interact with a wide variety of bioactive molecules, e.g. cytokines, growth factors, ...
TMPY-04356 GSK3B Protein, Human, Recombinant (His)

glycogen synthase kinase 3 beta,glycogen syntha...

Human Baculovirus Insect Cells
GSK3B Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 50.4 kDa and the accession number is P49841-2.
TMPH-03412 Citrate synthase Protein, Rickettsia australis, Recombinant (His & Myc)

gltA,Citrate synthase

Rickettsia australis E. coli
Citrate synthase Protein, Rickettsia australis, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 53.6 kDa and the accession number is P51039.
TMPY-05069 Prostaglandin D2 Synthase Protein, Rat, Recombinant (His)

prostaglandin D2 synthase 21kDa (brain)

Rat HEK293 Cells
Prostaglandin D2 Synthase Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.3 kDa and the accession number is A6JT70.
TMPH-03585 Dihydropteroate synthase Protein, S. haemolyticus, Recombinant (His)

folP,Dihydropteroate synthase,DHPS,Dihydropteroate ...

Staphylococcus haemolyticus E. coli
Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives. Dihydropteroate synthase Protein, S. haemolyticus, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 33.6 kDa and the accession number is Q59919.
TMPH-00710 PEP synthase Protein, E. coli, Recombinant (His & SUMO)

ppsA,Phosphoenolpyruvate synthase,Pyruvate, water d...

E. coli E. coli
Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.
TMPH-01603 Lanosterol synthase/LSS Protein, Human, Recombinant (His)

Lanosterol synthase,LSS,2,3-epoxysqualene--lanoster...

Human E. coli
Key enzyme in the cholesterol biosynthesis pathway. Catalyzes the cyclization of (S)-2,3 oxidosqualene to lanosterol, a reaction that forms the sterol nucleus. Through the production of lanosterol may regulate lens protein aggregation and increase transparency.
TMPH-00040 EPSP synthase Protein, Agrobacterium sp., Recombinant (His)

3-phosphoshikimate 1-carboxyvinyltransferase,5-enolpyruvylsh...

Agrobacterium HEK293 Cells
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. EPSP synthase Protein, Agrobacterium sp., Recombinant (His) is expressed in HEK293 mammalian cells with N-6xHis-Myc tag. The predicted molecular weight is 51.6 kDa and the accession number is Q9R4E4.
TMPH-00709 DAHP synthase Protein, E. coli, Recombinant (His)

Phospho-2-dehydro-3-deoxyheptonate aldolase, Trp-sensitive,P...

E. coli E. coli
Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP). DAHP synthase Protein, E. coli, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 42.8 kDa and the accession number is P00887.
TMPH-03057 Chorismate synthase Protein, Neurospora crassa, Recombinant (His)

B7F21.10,NCU05420,aro-2,5-enolpyruvylshikimate-3-phosphate p...

Neurospora crassa E. coli
Bifunctional enzyme that possesses chorismate synthase and intrinsic flavin reductase activity, it uses NADPH to reduce FMN.
TMPY-04624 Prostaglandin D2 Synthase Protein, Mouse, Recombinant (His)

Ptgs3,L-PGDS,prostaglandin D2 synthase 21kDa (brain...

Mouse HEK293 Cells
Prostaglandin D2 Synthase Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 19.9 kDa and the accession number is O09114-1.
TMPH-03189 EPSP synthase Protein, Pseudomonas sp., Recombinant (His & Myc)

5-enolpyruvylshikimate-3-phosphate synthase,3-phosp...

Pseudomonas E. coli
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. EPSP synthase Protein, Pseudomonas sp., Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 54.7 kDa and the accession number is P0A2Y4.
TMPH-00041 EPSP synthase Protein, Agrobacterium sp., Recombinant (His & SUMO)

3-phosphoshikimate 1-carboxyvinyltransferase,aroA,5-enolpyru...

Agrobacterium E. coli
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. EPSP synthase Protein, Agrobacterium sp., Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 63.6 kDa and the accession number is Q9R4E4.
TMPH-00566 EPSP synthase Protein, E. coli, Recombinant (His & Myc)

5-enolpyruvylshikimate-3-phosphate synthase,3-phosp...

E. coli E. coli
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. EPSP synthase Protein, E. coli, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 53.5 kDa and the accession number is P0A6D3.
TMPH-03596 Holo-ACP synthase Protein, S. pyogenes serotype M28, Recombinant (His & Myc)

acpS,4'-phosphopantetheinyl transferase AcpS,Holo-[acyl-carr...

Streptococcus pyogenes Baculovirus Insect Cells
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein. Holo-ACP synthase Protein, S. pyogenes serotype M28, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predicted molecular weight is 17.1 kDa and the accession number is Q48RM7.
TMPH-00664 EPSP synthase Protein, E. coli O157:H7, Recombinant (His & Myc)

5-enolpyruvylshikimate-3-phosphate synthase,3-phosp...

E. coli E. coli
Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
TMPH-03597 Holo-ACP synthase Protein, S. pyogenes serotype M28, Recombinant (E. coli, His & Myc)

4'-phosphopantetheinyl transferase AcpS,Holo-[acyl-carrier-p...

Streptococcus pyogenes E. coli
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein. Holo-ACP synthase Protein, S. pyogenes serotype M28, Recombinant (E. coli, His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 18.3 kDa and the accession number is Q48RM7.
TMPY-01736 COX-2 Protein, Human, Recombinant (His)

GRIPGHS,PHS-2,hCox-2,COX-2,PGHS-2,prostaglandin-endoperoxide...

Human Baculovirus Insect Cells
PTGS2, also known as COX-2, is s component of Prostaglandin-endoperoxide synthase (PTGS). PTGS, also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. PTGS2 is overexpressed in many cancers. The overexpression of PTGS2 along with increased angiogenesis and GLUT-1 expression ...
TMPH-02715 HAS2 Protein, Mouse, Recombinant (His)

Hyaluronic acid synthase 2,Hyaluronate synthase...

Mouse E. coli
HAS2 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 39.9 kDa and the accession number is P70312.
TMPH-03714 HAS1 Protein, Xenopus tropicalis, Recombinant (His & Myc)

Hyaluronic acid synthase 1,has1,Hyaluronan synt...

Xenopus tropicalis E. coli
Catalyzes the addition of GlcNAc or GlcUA monosaccharides to the nascent hyaluronan polymer. Therefore, it is essential to hyaluronan synthesis a major component of most extracellular matrices that has a structural role in tissues architectures and regulates cell adhesion, migration and differentiation. Also able to catalyze the synthesis of chito-oligosaccharide depending on the substrate.
TMPJ-00820 Trp B Protein, E. coli, Recombinant (His)

trpB,Tryptophan synthase β chain,Tryptophan syn...

E. coli E. coli
Trp B Protein, E. coli, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 40-50 KDa and the accession number is P0A879.
TMPJ-00520 NANS Protein, Human, Recombinant (His)

N-Acetylneuraminic Acid Synthase,N-Acetylneuraminic...

Human E. coli
Sialic Acid Synthase (NANS) is an enzyme that contains one AFP-like domain. NANS is ubiquitous and plays a role in the biosynthetic pathways of sialic acids. NANS produces N-acetylneuraminic acid (Neu5Ac) and 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN). It also can use N-acetylmannosamine 6-phosphate and mannose 6-phosphate as substrates to generate phosphorylated forms of Neu5Ac and KDN, respectively.
TMPH-02477 ALAS1 Protein, Mouse, Recombinant (His & Myc)

Delta-ALA synthase 1,Delta-aminolevulinate synt...

Mouse E. coli
ALAS1 Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 72.3 kDa and the accession number is Q8VC19.
TMPH-01323 FDPS Protein, Human, Recombinant (His & SUMO)

(2E,6E)-farnesyl diphosphate synthase,Dimethylallyl...

Human E. coli
FDPS Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 64.3 kDa and the accession number is P14324.
TMPJ-00819 Trp A Protein, E. coli, Recombinant

Tryptophan synthase α chain,trpA,Tryptophan syn...

E. coli E. coli
Trp A Protein, E. coli, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 27 KDa and the accession number is P0A877.
TMPY-06686 FASN Protein, Mouse, Recombinant (His)

fatty acid synthase,FAS,A630082H08Rik

Mouse E. coli
FASN Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 34.23 kDa and the accession number is P19096.
TMPJ-00806 HMBS Protein, Human, Recombinant (His)

Pre-Uroporphyrinogen Synthase,PBG-D,Hydroxymethylbi...

Human HEK293 Cells
Porphobilinogen Deaminase (HMBS) is a member of the HMBS family. PBGD is the third enzyme of the heme biosynthetic pathway and catalyzes the head to tail condensation of four porphobilinogen molecules into the linear hydroxymethylbilane. HMBS is involved in the production of heme, which is important for all of the body's organs, although it is most abundant in the blood, bone marrow, and liver. In addition, Heme is an essential component of iron-containing proteins called hemoproteins, including...
TMPH-03045 NadA Protein, MenB, Recombinant (His)

Quinolinate synthase,nadA

MenB E. coli
Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
TMPH-03402 STR1 Protein, Rauvolfia serpentina, Recombinant (His & Myc)

STR1,Strictosidine synthase

Rauvolfia serpentina E. coli
Catalyzes the stereospecific condensation of tryptamine with secologanin to form strictosidine, the key intermediate of indole alkaloid biosynthesis. STR1 Protein, Rauvolfia serpentina, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 43.2 kDa and the accession number is P68175.
TMPH-03047 NadA Protein, MenC, Recombinant (His)

Quinolinate synthase,nadA

MenB E. coli
Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. NadA Protein, MenC, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 44.1 kDa and the accession number is A1KVN9.
TMPH-01166 CGAS Protein, Human, Recombinant (His)

Cyclic GMP-AMP synthase,cGAMP synthase,CGA...

Human E. coli
CGAS Protein, Human, Recombinant (His) is expressed in E. coli.
TMPY-03452 PTS Protein, Human, Recombinant (His)

PTPS,PTS,6-pyruvoyltetrahydropterin synthase

Human E. coli
PTS(6-pyruvoyltetrahydropterin synthase) belongs to the PTPS family. It catalyzes the elimination of inorganic triphosphate from dihydroneopterin triphosphate, which is the second and irreversible step in the biosynthesis of tetrahydrobiopterin from GTP. Tetrahydrobiopterin, also known as BH(4), is an essential cofactor and regulator of various enzyme activities, including enzymes involved in serotonin biosynthesis and NO synthase activity. Mutations in this gene result in hyperphenylalaninemia....
TMPH-02530 ATP5B Protein, Mouse, Recombinant (His & Myc & SUMO)

ATP synthase F1 subunit beta,Atp5b,Atp5f1b,ATP ...

Mouse E. coli
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain ...
TMPH-00565 FabB Protein, E. coli, Recombinant (His & Myc & SUMO)

Beta-ketoacyl-ACP synthase I,3-oxoacyl-[acyl-carrie...

E. coli E. coli
FabB Protein, E. coli, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO and C-Myc tag. The predicted molecular weight is 61.3 kDa and the accession number is P0A953.
TMPH-02717 HMGCS1 Protein, Mouse, Recombinant (His & SUMO)

Hmgcs1,3-hydroxy-3-methylglutaryl coenzyme A synthase

Mouse E. coli
Catalyzes the condensation of acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is converted by HMG-CoA reductase (HMGCR) into mevalonate, a precursor for cholesterol synthesis. HMGCS1 Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 73.6 kDa and the accession number is Q8JZK9.
TMPH-03524 KAS III Protein, S. aureus, Recombinant (His & Myc)

3-oxoacyl-[acyl-carrier-protein] synthase 3,3-oxoac...

Staphylococcus aureus E. coli
Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids. KAS III Protein, S. au...
TMPH-01321 FLAD1 Protein, Human, Recombinant (His)

FLAD1,FMN adenylyltransferase,FAD pyrophosphorylase,FAD ...

Human E. coli
Catalyzes the adenylation of flavin mononucleotide (FMN) to form flavin adenine dinucleotide (FAD) coenzyme. FLAD1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 58.3 kDa and the accession number is Q8NFF5.
TMPY-01113 SGMS2 Protein, Human, Recombinant (mFc)

SMS2,sphingomyelin synthase 2

Human HEK293 Cells
SGMS2 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 35.7 kDa and the accession number is A0A024RDH4.
TMPY-01480 LTC4S Protein, Human, Recombinant (His)

LTC4S,MGC33147,leukotriene C4 synthase

Human Baculovirus Insect Cells
Leukotriene C4 synthase, also known as LTC4 synthase, Leukotriene-C(4) synthase, and LTC4S, is a multi-pass membrane protein that belongs to the MAPEG family. LTC4S is detected in the lung, platelets, and the myelogenous leukemia cell line KG-1 (at protein level). LTC4S activity is present in eosinophils, basophils, mast cells, certain phagocytic mononuclear cells, endothelial cells, vascular smooth muscle cells, and platelets. LTC4S is essential for the production of cysteinyl leukotrienes (Cys...
TMPJ-00982 DHS Protein, Human, Recombinant (His)

DS,Deoxyhypusine Synthase,DHPS,DHS

Human E. coli
Human Deoxyhypusine Synthase (DHS) is vital for the first step of hypusine biosynthesis. DHS catalyzes the NAD-dependent oxidative cleavage of spermidine, the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue.
TMPY-02654 FDPS Protein, Human, Recombinant (His)

FPS,FPPS,Farnesyl pyrophosphate synthase

Human E. coli
FDPS Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 42.4 kDa and the accession number is P14324-2.
TMPH-00967 ATP5F1B Protein, Human, Recombinant (His & Myc & SUMO)

ATP5B,ATP synthase F1 subunit beta,ATP5F1B,ATPSB,AT...

Human E. coli
ATP5F1B Protein, Human, Recombinant (His & Myc & SUMO) is expressed in E. coli.
TMPH-00017 acpS Protein, Acholeplasma laidlawii, Recombinant (His & Myc)

Holo-ACP synthase,Holo-[acyl-carrier-protein] s...

Acholeplasma laidlawii E. coli
Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein. acpS Protein, Acholeplasma laidlawii, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 20.9 kDa and the accession number is A9NHV3.
TMPY-00330 GGPS1 Protein, Human, Recombinant (His)

GGPPS1,geranylgeranyl diphosphate synthase 1,GGPPS

Human HEK293 Cells
GGPS1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.3 kDa and the accession number is A0A024R3R2.
TMPH-00964 ATP5PB Protein, Human, Recombinant (His & Myc)

ATP synthase proton-transporting mitochondrial F(0)...

Human E. coli
ATP5PB Protein, Human, Recombinant (His & Myc) is expressed in E. coli.
TMPH-00966 ATP5F1B Protein, Human, Recombinant (His)

ATP synthase F1 subunit beta,ATP synthase ...

Human P. pastoris (Yeast)
ATP5F1B Protein, Human, Recombinant (His) is expressed in Yeast.
TMPH-00425 DNA ligase Protein, Colwellia psychrerythraea, Recombinant (His)

ligA,DNA ligase,Polydeoxyribonucleotide synthase [N...

Colwellia psychrerythraea E. coli
DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. DNA ligase Protein, Colwellia psychrerythraea, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 42.1 kDa and the accession number is Q47YI0.
TMPH-03249 ATP5F1B Protein, Rat, Recombinant (His & Myc)

ATPMB,ATPSB,ATP synthase subunit beta, mitochondria...

Rat E. coli
ATP5F1B Protein, Rat, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 59.2 kDa and the accession number is P10719.
TMPH-00226 ATPase subunit g Protein, Bovine, Recombinant (His & Myc)

ATP synthase subunit g, mitochondrial,ATP5MG,ATP

Bovine E. coli
ATPase subunit g Protein, Bovine, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 18.7 kDa and the accession number is Q28852.
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重组蛋白

Prostaglandin D2 Synthase Protein, Human, Recombinant (His)
Cat.No: TMPY-03120
Species: Human
Expression System: HEK293 Cells
Citrate Synthase Protein, Human, Recombinant (His)
Cat.No: TMPY-04070
Species: Human
Expression System: Baculovirus Insect Cells
GSK3B Protein, Human, Recombinant (His)
Cat.No: TMPY-04356
Species: Human
Expression System: Baculovirus Insect Cells
Citrate synthase Protein, Rickettsia australis, Recombinant (His & Myc)
Cat.No: TMPH-03412
Species: Rickettsia australis
Expression System: E. coli
Prostaglandin D2 Synthase Protein, Rat, Recombinant (His)
Cat.No: TMPY-05069
Species: Rat
Expression System: HEK293 Cells
Dihydropteroate synthase Protein, S. haemolyticus, Recombinant (His)
Cat.No: TMPH-03585
Species: Staphylococcus haemolyticus
Expression System: E. coli
PEP synthase Protein, E. coli, Recombinant (His & SUMO)
Cat.No: TMPH-00710
Species: E. coli
Expression System: E. coli
Lanosterol synthase/LSS Protein, Human, Recombinant (His)
Cat.No: TMPH-01603
Species: Human
Expression System: E. coli
EPSP synthase Protein, Agrobacterium sp., Recombinant (His)
Cat.No: TMPH-00040
Species: Agrobacterium
Expression System: HEK293 Cells
DAHP synthase Protein, E. coli, Recombinant (His)
Cat.No: TMPH-00709
Species: E. coli
Expression System: E. coli
Chorismate synthase Protein, Neurospora crassa, Recombinant (His)
Cat.No: TMPH-03057
Species: Neurospora crassa
Expression System: E. coli
Prostaglandin D2 Synthase Protein, Mouse, Recombinant (His)
Cat.No: TMPY-04624
Species: Mouse
Expression System: HEK293 Cells
EPSP synthase Protein, Pseudomonas sp., Recombinant (His & Myc)
Cat.No: TMPH-03189
Species: Pseudomonas
Expression System: E. coli
EPSP synthase Protein, Agrobacterium sp., Recombinant (His & SUMO)
Cat.No: TMPH-00041
Species: Agrobacterium
Expression System: E. coli
EPSP synthase Protein, E. coli, Recombinant (His & Myc)
Cat.No: TMPH-00566
Species: E. coli
Expression System: E. coli
Holo-ACP synthase Protein, S. pyogenes serotype M28, Recombinant (His & Myc)
Cat.No: TMPH-03596
Species: Streptococcus pyogenes
Expression System: Baculovirus Insect Cells
EPSP synthase Protein, E. coli O157:H7, Recombinant (His & Myc)
Cat.No: TMPH-00664
Species: E. coli
Expression System: E. coli
Holo-ACP synthase Protein, S. pyogenes serotype M28, Recombinant (E. coli, His & Myc)
Cat.No: TMPH-03597
Species: Streptococcus pyogenes
Expression System: E. coli
COX-2 Protein, Human, Recombinant (His)
Cat.No: TMPY-01736
Species: Human
Expression System: Baculovirus Insect Cells
HAS2 Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02715
Species: Mouse
Expression System: E. coli
HAS1 Protein, Xenopus tropicalis, Recombinant (His & Myc)
Cat.No: TMPH-03714
Species: Xenopus tropicalis
Expression System: E. coli
Trp B Protein, E. coli, Recombinant (His)
Cat.No: TMPJ-00820
Species: E. coli
Expression System: E. coli
NANS Protein, Human, Recombinant (His)
Cat.No: TMPJ-00520
Species: Human
Expression System: E. coli
ALAS1 Protein, Mouse, Recombinant (His & Myc)
Cat.No: TMPH-02477
Species: Mouse
Expression System: E. coli
FDPS Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-01323
Species: Human
Expression System: E. coli
Trp A Protein, E. coli, Recombinant
Cat.No: TMPJ-00819
Species: E. coli
Expression System: E. coli
FASN Protein, Mouse, Recombinant (His)
Cat.No: TMPY-06686
Species: Mouse
Expression System: E. coli
HMBS Protein, Human, Recombinant (His)
Cat.No: TMPJ-00806
Species: Human
Expression System: HEK293 Cells
NadA Protein, MenB, Recombinant (His)
Cat.No: TMPH-03045
Species: MenB
Expression System: E. coli
STR1 Protein, Rauvolfia serpentina, Recombinant (His & Myc)
Cat.No: TMPH-03402
Species: Rauvolfia serpentina
Expression System: E. coli
NadA Protein, MenC, Recombinant (His)
Cat.No: TMPH-03047
Species: MenB
Expression System: E. coli
CGAS Protein, Human, Recombinant (His)
Cat.No: TMPH-01166
Species: Human
Expression System: E. coli
PTS Protein, Human, Recombinant (His)
Cat.No: TMPY-03452
Species: Human
Expression System: E. coli
ATP5B Protein, Mouse, Recombinant (His & Myc & SUMO)
Cat.No: TMPH-02530
Species: Mouse
Expression System: E. coli
FabB Protein, E. coli, Recombinant (His & Myc & SUMO)
Cat.No: TMPH-00565
Species: E. coli
Expression System: E. coli
HMGCS1 Protein, Mouse, Recombinant (His & SUMO)
Cat.No: TMPH-02717
Species: Mouse
Expression System: E. coli
KAS III Protein, S. aureus, Recombinant (His & Myc)
Cat.No: TMPH-03524
Species: Staphylococcus aureus
Expression System: E. coli
FLAD1 Protein, Human, Recombinant (His)
Cat.No: TMPH-01321
Species: Human
Expression System: E. coli
SGMS2 Protein, Human, Recombinant (mFc)
Cat.No: TMPY-01113
Species: Human
Expression System: HEK293 Cells
LTC4S Protein, Human, Recombinant (His)
Cat.No: TMPY-01480
Species: Human
Expression System: Baculovirus Insect Cells
DHS Protein, Human, Recombinant (His)
Cat.No: TMPJ-00982
Species: Human
Expression System: E. coli
FDPS Protein, Human, Recombinant (His)
Cat.No: TMPY-02654
Species: Human
Expression System: E. coli
ATP5F1B Protein, Human, Recombinant (His & Myc & SUMO)
Cat.No: TMPH-00967
Species: Human
Expression System: E. coli
acpS Protein, Acholeplasma laidlawii, Recombinant (His & Myc)
Cat.No: TMPH-00017
Species: Acholeplasma laidlawii
Expression System: E. coli
GGPS1 Protein, Human, Recombinant (His)
Cat.No: TMPY-00330
Species: Human
Expression System: HEK293 Cells
ATP5PB Protein, Human, Recombinant (His & Myc)
Cat.No: TMPH-00964
Species: Human
Expression System: E. coli
ATP5F1B Protein, Human, Recombinant (His)
Cat.No: TMPH-00966
Species: Human
Expression System: P. pastoris (Yeast)
DNA ligase Protein, Colwellia psychrerythraea, Recombinant (His)
Cat.No: TMPH-00425
Species: Colwellia psychrerythraea
Expression System: E. coli
ATP5F1B Protein, Rat, Recombinant (His & Myc)
Cat.No: TMPH-03249
Species: Rat
Expression System: E. coli
ATPase subunit g Protein, Bovine, Recombinant (His & Myc)
Cat.No: TMPH-00226
Species: Bovine
Expression System: E. coli
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Cat. No. Product Name Target Signaling Pathways
T13028 Sulfamerazine D4

Others Others
Sulfamerazine D4, a deuterium-labeled version of Sulfamerazine, acts as a sulfonamide antibacterial. It inhibits the bacterial synthesis of dihydrofolic acid by competing with para-aminobenzoic acid (PABA) for the binding site on dihydropteroate synthase.
T31813 Fludalanine

MK641,D-Alanine-2-d, 3-fluoro-,3-Fluoro-D-(2-2H)alanine

Fludalanine (MK641), an analogue of D-alanine, irreversiably inactivates racemase and also inhibits synthase. When used in combination with cycloserine, it has been found to be more active against a variety of non-mycobacterium organisms than fludalanine
T73716 Miglustat-d9 HCl

Miglustat-d9 (hydrochloride)为Miglustat (hydrochloride)的氘代物,属于葡萄糖神经酰胺合成酶抑制剂,主要用于治疗I型戈谢病。
T36895 5-Fluorouracil-13C,15N2

5-Fluorouracil-13C,15N2

5-Fluorouracil-13C,15N2 is intended for use as an internal standard for the quantification of 5-flurouracil by GC- or LC-MS. 5-Fluorouracil is a pyrimidine analog that irreversibly inhibits thymidylate synthase, blocking the synthesis of thymidine which is required for DNA synthesis. Intracellular metabolites of 5-fluorouracil exert cytotoxic effects by either inhibiting thymidylate synthetase, or through incorporation into RNA and DNA, ultimately initiating apoptosis.
T35697 Lauric Acid-13C

Lauric acid-13C is intended for use as an internal standard for the quantification of lauric acid by GC- or LC-MS. Lauric acid is a medium-chain saturated fatty acid. It has been found at high levels in coconut oil.1Lauric acid induces the activation of NF-κB and the expression of COX-2, inducible nitric oxide synthase (iNOS), and IL-1α in RAW 264.7 cells when used at a concentration of 25 μM.2
TMIH-0361 N,N'-Dimethylarginine-d6

N,N'-Dimethylarginine-d6 是 N,N'-Dimethylarginine 的氘代化合物。N,N'-Dimethylarginine 的 CAS 号为 30344-00-4。SDMA 是一氧化氮 (NO) 合酶的内源性抑制剂。
T71288 Phenylbutazone-d9

Phenylbutazone-d9 is intended for use as an internal standard for the quantification of phenylbutazone by GC- or LC-MS. Phenylbutazone is a non-steroidal anti-inflammatory drug and an inhibitor of the peroxidase activity of COX (IC50 = ~100 µM in the presence of hydrogen peroxide). It also inhibits prostaglandin I synthase (IC50 = ~25 µM in the presence of hydrogen peroxide). Phenylbutazone (2 mg/kg) reduces increases in type II collagen levels in the inflamed joints of an equine model of LPS-in...
T70990 ADMA-d6

NG,NG-dimethyl-L-arginine-d6 (ADMA-d6) (hydrochloride) is intended for use as an internal standard for the quantification of NG,NG-dimethyl-L-arginine by GC- or LC-MS. ADMA is an endogenous inhibitor of nitric oxide synthase (NOS). It is formed from arginine by protein arginine methyltransferases (PRMTs) and degraded by dimethylarginine dimethylaminohydrolases (DDAHs) and alanine-glyoxylate aminotransferase 2 (AGXT2). ADMA levels are increased concomitant with an increase in blood pressure in Da...
TMIH-0457 Proguanil-d6 HCl

Proguanil-d6 HCl 是 Proguanil HCl 的氘代化合物。Proguanil HCl 的 CAS 号为 637-32-1。Proguanil hydrochloride 是一种双胍类抗疟疾剂,在体内代谢形成环胍。它还是一种二氢叶酸还原酶抑制剂。
T69600 Spermidine-d6

Spermidine-d6 is intended for use as an internal standard for the quantification of spermidine by GC- or LC-MS. Spermidine is an endogenous polyamine. It is formed from putrescine by spermidine synthase. Spermidine (25 µM) inhibits the activity of the human inward-rectifying potassium channel Kir2.3 in a patch-clamp assay. It induces autophagy in HeLa cells when used at a concentration of 100 µM and increases the lifespan of D. melanogaster, yeast, and C. elegans. Spermidine (30 mM in the drinki...
T70882 Orlistat-d3

Orlistat-d3 is intended for use as an internal standard for the quantification of orlistat by GC- or LC-MS. Orlistat is a digestive lipase inhibitor. It inhibits diacylglycerol lipase α (DAGLα), DAGLβ, α/β-hydrolase domain-containing protein 12 (ABHD12), ABHD16A, and platelet-activating factor acetylhydrolase (PAF-AH; IC50s = 0.06, 0.1, 0.08, 0.03, and 0.05 µM, respectively), as well as pancreatic lipase and hormone-sensitive lipase (IC50s = 0.65 and 2.1 µg/ml, respectively) but does not inhibit...
T35789 Palmitic acid-1-13C

Palmitic acid-13C is intended for use as an internal standard for the quantification of palmitic acid by GC- or LC-MS. Palmitic acid is a 16-carbon saturated fatty acid. It comprises approximately 25% of human total plasma lipids.1 It increases protein levels of COX-2 in RAW 264.7 cells when used at a concentration of 75 μM.2 Palmitic acid is involved in the acylation of proteins to anchor membrane-bound proteins to the lipid bilayer.2,3,4,5,6 |1. Santos, M.J., López-Jurado, M., Llopis, J., et a...
T35791 Palmitic acid-13C

Palmitic acid-13C is intended for use as an internal standard for the quantification of palmitic acid by GC- or LC-MS. Palmitic acid-13C contains 13C at the C2 position and has been used in the study of free fatty acid incorporation into phospholipid fatty acids in soil microbes.1 Palmitic acid is a 16-carbon saturated fatty acid. It comprises approximately 25% of human total plasma lipids.2 It increases protein levels of COX-2 in RAW 264.7 cells when used at a concentration of 75 μM.3 Palmitic ...

同位素标记化合物

Sulfamerazine D4
Cat.No: T13028
Synonym:
Target: Others
Fludalanine
Cat.No: T31813
Synonym: MK641,D-Alanine-2-d, 3-fluoro-,3-Fluoro-D-(2-2H)alanine
Target:
Miglustat-d9 HCl
Cat.No: T73716
Synonym:
Target:
5-Fluorouracil-13C,15N2
Cat.No: T36895
Synonym: 5-Fluorouracil-13C,15N2
Target:
Lauric Acid-13C
Cat.No: T35697
Synonym:
Target:
N,N'-Dimethylarginine-d6
Cat.No: TMIH-0361
Synonym:
Target:
Phenylbutazone-d9
Cat.No: T71288
Synonym:
Target:
ADMA-d6
Cat.No: T70990
Synonym:
Target:
Proguanil-d6 HCl
Cat.No: TMIH-0457
Synonym:
Target:
Spermidine-d6
Cat.No: T69600
Synonym:
Target:
Orlistat-d3
Cat.No: T70882
Synonym:
Target:
Palmitic acid-1-13C
Cat.No: T35789
Synonym:
Target:
Palmitic acid-13C
Cat.No: T35791
Synonym:
Target:
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