|
TMPY-02342
|
MIF Protein, Mouse, Recombinant
GIF,macrophage migration inhibitory factor (glycosy...
|
Mouse
|
E. coli
|
|
MIF Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 12.5 kDa and the accession number is P34884. |
|
TMPH-00004
|
RAC1 Protein, Human, Recombinant (His)
Ras-like protein TC25,p21-Rac1,RAC1,Cell migration-...
|
Human
|
P. pastoris (Yeast)
|
|
RAC1 Protein, Human, Recombinant (His) is expressed in yeast with C-6xHis tag. The predicted molecular weight is 24.6 kDa; 30 kDa, reducing conditions and the accession number is P63000. |
|
TMPH-00638
|
RuvB Protein, E. coli, Recombinant (His & SUMO)
ruvB,Holliday junction branch migration complex sub...
|
E. coli
|
E. coli
|
|
The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvB Protein, E. coli, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 53.2 kDa and the accession number is ... |
|
TMPY-02145
|
MIF Protein, Mouse, Recombinant (His)
GIF,macrophage migration inhibitory factor (glycosy...
|
Mouse
|
HEK293 Cells
|
|
MIF Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 13.8 kDa and the accession number is P34884. |
|
TMPH-00637
|
RuvA Protein, E. coli, Recombinant (His & SUMO)
ruvA,Holliday junction branch migration complex sub...
|
E. coli
|
E. coli
|
|
RuvA Protein, E. coli, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 38.1 kDa and the accession number is P0A809. |
|
TMPY-02095
|
MIF Protein, Human, Recombinant (His)
macrophage migration inhibitory factor (glycosylati...
|
Human
|
HEK293 Cells
|
|
MIF Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 13.8 kDa and the accession number is P14174. |
|
TMPH-02572
|
TMEM2 Protein, Mouse, Recombinant (His)
Transmembrane protein 2,Cell migration-inducing hya...
|
Mouse
|
E. coli
|
|
Cell surface hyaluronidase that mediates the initial cleavage of extracellular high-molecular-weight hyaluronan into intermediate-size hyaluronan of approximately 5 kDa fragments. Acts as a regulator of angiogenesis and heart morphogenesis by mediating degradation of extracellular hyaluronan, thereby regulating VEGF signaling. Is very specific to hyaluronan; not able to cleave chondroitin sulfate or dermatan sulfate. |
|
TMPJ-00727
|
PGK1 Protein, Human, Recombinant (His)
Phosphoglycerate kinase 1,Primer recognition protein 2,PGK1,...
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Human
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HEK293 Cells
|
|
Phosphoglycerate kinase 1(PGK1) is an enzyme. It is mainly expressed in spermatogonia and Localized on the principle piece in the sperm. Its expression significantly decreased in the testis of elderly men. PGK1 involved in a critical energy-producing process known as glycolysis. It helps carry out a chemical reaction that converts a molecule called 1,3-diphosphoglycerate, which is produced during the breakdown of glucose, to another molecule called 3-phosphoglycerate during glycolysis. PGK1 may ... |
|
TMPH-03358
|
S100A9 Protein, Rat, Recombinant (His & SUMO)
Myeloid-related protein 14,S100a9,Protein S100-A9,Calgranuli...
|
Rat
|
E. coli
|
|
S100A9 Protein, Rat, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 29.0 kDa and the accession number is P50116. |
|
TMPJ-00991
|
S100A8 Protein, Rat, Recombinant (His)
Leukocyte L1 complex light chain,Migration inhibito...
|
Rat
|
E. coli
|
|
Protein S100-A8(Mrp8) contains 2 EF-hand domains and belongs to the S-100 family. Mrp8 binds two calcium ions per molecule with an affinity similar to that of the S-100 proteins. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. It may function in the inhi... |
|
TMPK-00807
|
Osteopontin Protein, Mouse, Recombinant (His)
ETA-1,SPP1,OPN,Bone sialoprotein 1,BNSP,SPP-1,Osteopontin,Ne...
|
Mouse
|
HEK293 Cells
|
|
Secreted phosphoprotein 1 (SPP1) expression in TAMs isolated from lung adenocarcinoma tissues and PMA-treated THP-1 cells were measured. Macrophage polarization was identified by flow cytometric analysis. Cell migration and apoptosis were assessed by Transwell migration assays and flow cytometric analysis, respectively. SPP1 is highly expressed in tumor tissues and TAMs isolated from patients with an advanced TNM stage, and also in PMA-treated THP-1 cells. |
|
TMPK-00022
|
Galectin-1 Protein, Human, Recombinant (hFc)
GAL1,LGALS1,Galectin-1,S-Lac lectin 1,DKFZp686E23103,GBP,Gal...
|
Human
|
HEK293 Cells
|
|
Galectin 1 (Gal-1), a β-galactoside binding mammalian lectin of 14KDa, is implicated in many signalling pathways, immune responses associated with cancer progression and immune disorders. Inhibition of human Gal-1 has been regarded as one of the potential therapeutic approaches for the treatment of cancer, as it plays a major role in tumour development and metastasis by modulating various biological functions viz. apoptosis, angiogenesis, migration, cell immune escape. |
|
TMPH-00010
|
MMP-14 Protein, Human, Recombinant (His & SUMO)
Membrane-type-1 matrix metalloproteinase,MMP14,Membrane-type...
|
Human
|
E. coli
|
|
Endopeptidase that degrades various components of the extracellular matrix such as collagen. Activates progelatinase A. Essential for pericellular collagenolysis and modeling of skeletal and extraskeletal connective tissues during development. May be involved in actin cytoskeleton reorganization by cleaving PTK7. Acts as a positive regulator of cell growth and migration via activation of MMP15. Involved in the formation of the fibrovascular tissues in association with pro-MMP2. Cleaves ADGRB1 to... |
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TMPK-00305
|
TGFBR1 Protein, Human, Recombinant (mFc & Avi)
tbetaR-I,TGFβRI,TGFbetaRI,LDS2A,ALK-5,TGF-beta RI,tβR-I,TGF-...
|
Human
|
HEK293 Cells
|
|
transforming growth factor beta receptor 1 (TGFBR1), a key stimulator of tumor proliferation and metastasis, was a direct target of miR‑98‑5p. miR‑98‑5p overexpression resulted in the downregulation of TGFBR1 and the suppression of the viability, proliferation, migration and invasion of A549 and H1299 cells. TGFBR1 Protein, Human, Recombinant (mFc & Avi) is expressed in HEK293 mammalian cells with C-mFc-Avi tag. The predicted molecular weight is 38.2 kDa and the accession number is P36897-1. |
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TMPJ-00842
|
FGF-2 Protein, Rat, Recombinant
bFGF,Heparin-Binding Growth Factor 2,FGFB,Fibroblast Growth ...
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Rat
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E. coli
|
|
FGF-basic is a members of the Fibroblast Growth Factors (FGFs) family. The family constitutes a large family of proteins involved in many aspects of development including cell proliferation, growth, and differentiation. They act on several cell types to regulate diverse physiologic functions including angiogenesis, cell growth, pattern formation, embryonic development, metabolic regulation, cell migration, neurotrophic effects, and tissue repair. FGF-basic is a non-glycosylated heparin binding g... |
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TMPJ-00090
|
FGF-9 Protein, Human, Recombinant
Fibroblast Growth Factor 9,Heparin-Binding Growth Factor 9,F...
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Human
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E. coli
|
|
Fibroblast Growth Factor 9 (FGF-9) belongs to the Fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF-9 plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. In addition, FGF-9 may have a role in glial c... |
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TMPY-04779
|
BTN3A2 Protein, Human, Recombinant (His)
BTF3,BT3.2,BTF4,BTN3.2,CD277,butyrophilin subfamily 3 member...
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Human
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HEK293 Cells
|
|
The three butyrophilin BTN3A molecules, BTN3A1, BTN3A2, and BTN3A3, are members of the B7/butyrophilin-like group of Ig superfamily receptors, which modulate the function of T cells. BTN3A2 is overexpressed in gastric tumors, and deletion of BTN3A2 inhibited proliferation, migration, and invasion of gastric cancer cells. The butyrophilin 3 (BTN3) receptors are implicated in the T lymphocytes regulation and present a wide plasticity in mammals. A thorough phylogenetic analysis reveals a concerted... |
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TMPJ-00166
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SCF Protein, Mouse, Recombinant
SCF,Hematopoietic growth factor KL,MGF,Steel factor,Mast cel...
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Mouse
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E. coli
|
|
Mouse stem cell factor (SCF), is the ligand for the receptor-type protein-tyrosine kinase KIT. It plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. KITLG/SCF binding can activate several signaling pathways. It also promotes phosphorylation of PIK3R1, which is the regulatory subunit of phosphatidylinositol 3-kinase, and subsequent activation of the ... |
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TMPJ-00562
|
PDGF-BB Protein, Mouse, Recombinant (His)
PDGFBB,PDGF-BB,血小板源生长因子
|
Mouse
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E. coli
|
|
Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF growth factor family. Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. PDGFB can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. As growth factor，it plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival... |
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TMPY-00365
|
GALNT7 Protein, Human, Recombinant (His)
GalNAcT7,polypeptide N-acetylgalactosaminyltransferase 7,GAL...
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Human
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HEK293 Cells
|
|
GalNAc-transferase-7 (GALNT7) is essential for the regulation of cell proliferation and has been implicated in tumorigenesis. Colorectal cancer (CRC) arises in a multistep molecular network process, which is from either discrete genetic perturbation or epigenetic dysregulation. GALNT7 acts as a glycosyltransferase in protein O-glycosylation, involving in the occurrence and development of CRC. GALNT7 silencing significantly attenuated the proliferation, clonogenicity and migration of LSCC cells a... |
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TMPJ-00327
|
M-CSF/CSF1 Protein, Human, Recombinant (His)
Lanimostim,M-CSF,CSF-1,MCSF,CSF1,集落刺激因子,Macrophage Colony-St...
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Human
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HEK293 Cells
|
|
Macrophage Colony-Stimulating Factors (m-csf) are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and themonocytes-macrophages. CSF-1 promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. It also plays an important role in the regulation of osteoclast proliferation and differentiation, the regulatio... |
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TMPJ-01218
|
M-CSF/CSF1 Protein, Rat, Recombinant
CSF1,集落刺激因子,CSF-1,Macrophage colony-stimulating factor 1,M-C...
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Rat
|
HEK293 Cells
|
|
Rat Macrophage colony-stimulating factor 1(MCSF,CSF1) is a single-pass type I membrane cytokine. It is a hematopoietic growth factor that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. MCSF promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. It is involved in the regu... |
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TMPY-00476
|
ITGB1 Protein, Human, Recombinant (His)
VLAB,integrin, beta 1 (fibronectin receptor, beta polypeptid...
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Human
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HEK293 Cells
|
|
ITGB1 (Integrin Subunit Beta 1) is a Protein Coding gene. This gene encodes a beta subunit, which is a type 1 transmembrane protein of the integrin beta chain family. ITGB1 is a heterodimeric cell-surface receptor involved in cell functions such as proliferation, migration, invasion, and survival. ITGB1 has been recognized to play a major role in tumor growth, invasion, and metastasis. Using luciferase assays, the researcher identified ITGB1 as a direct target of miR-134. ITGB1 is a direct targe... |
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TMPY-02953
|
TEM8/ANTXR1 Protein, Human, Recombinant (hFc)
ATR,TEM8,anthrax toxin receptor 1,GAPO
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Human
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HEK293 Cells
|
|
ANTXR1 contains 1 VWFA domain and belongs to the ATR family. ATR (Ataxia telangiectasia and Rad3 related) and ATM (Ataxia telangiectasia mutated) are closely related kinases that are activated by DNA damage. They are serine-threonine protein kinases and belongs to the phosphatidylinositol 3' kinase-like kinase (PIKK) family. Upon recruitment by the DNA damage binding proteins/complexes (ATRIP for ATR; MRN for ATM), ATM/ATR initiate the DNA damage checkpoint by phosphorylating a number of key pro... |
|
TMPY-02030
|
CD82 Protein, Human, Recombinant (His)
CD82 molecule,SAR2,R2,KAI-1,4F9,KAI1,C33,TSPAN27,ST6,IA4,GR1...
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Human
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HEK293 Cells
|
|
CD82, also known as KAI-1, structurally belongs to tetraspanin family while categorised as metastasis suppressor gene on functional grounds. KAI1/CD82 is localized on cell membrane and form interactions with other tetraspanins, integrins and chemokines which are respectively responsible for cell migration, adhesion and signalling. Downregulation of CD82 expression is associated with the advanced stages of many human cancers and correlates with the acquisition of metastatic potential. Recent stud... |
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TMPJ-00865
|
VEGF121 Protein, Human, Recombinant (His)
VEGFA,VEGF-A,Vascular permeability factor,VPF,血管内皮生长因子,Vascu...
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Human
|
HEK293 Cells
|
|
Human VEGF121, also known as Vascular endothelial growth factor A, VEGFA, Vascular permeability factor, VPF and VEGF, is a homodimeric, heparin-binding glycoprotein which belongs to the platelet-derived growth factor (PDGF)/vascular endothelial growth factor (VEGF) family. VEGF-A is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis, permeabilization of blood vessel... |
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TMPJ-01011
|
FGF-9 Protein, Mouse, Recombinant (His)
heparin-binding growth factor-9,GAF,HBGF-9,Glia-activating f...
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Mouse
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E. coli
|
|
Fibroblast growth factor-9 (FGF-9) is an approximately 26 kDa secreted glycoprotein of the FGF family. Secreted mouse FGF-9 lacks the N-terminal 1-3 aa and shares >98% sequence identity with rat, human, equine, porcine and bovine FGF-9. FGF-9 plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. In the mouse embryo the location and timing of FGF-9 expression affects development of the skeleton, cerebellum, lungs, heart, v... |
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TMPY-04830
|
GAS6 Protein, Mouse, Recombinant (His)
growth arrest-specific 6,Gas-6
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Mouse
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HEK293 Cells
|
|
The growth arrest-specific 6 gene (GAS6) is a member of the family of plasma vitamin K-dependent proteins, which are able to bind to phospholipids using an N-terminal gamma-carboxyglutamic acid domain. GAS6 is a vitamin K-dependent protein, plays a role in the survival, proliferation, migration, differentiation, adhesion, and apoptosis of cells. The growth arrest-specific 6 (GAS6) has been implicated in systemic inflammation and coagulation. Growth arrest-specific 6 (GAS6), plays a role in tumor... |
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TMPY-01085
|
VLDLR Protein, Human, Recombinant (His)
VLDLRCH,CAMRQ1,CHRMQ1,very low density lipoprotein receptor,...
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Human
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HEK293 Cells
|
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The very low density lipoprotein receptor, known as VLDLR, is a single-pass type 1 integral membrance protein and a member of the LDL receptor family. This receptor family includes LDL receptor, LRP, megalin, VLDLR and ApoER2, and is characterized by a cluster of cysteine-rich class A repeats, epidermal growth factor (EGF)-like repeats, YWTD repeats and an O-linked sugar sdomain. VLDLR contains 3 EGF-like domains, 8 LDL-receptor class A domains, as well as 6 LDL-receptor class B repeats, and is ... |
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TMPY-02550
|
Eotaxin/CCL11 Protein, Human, Recombinant (His)
SCYA11,chemokine (C-C motif) ligand 11
|
Human
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E. coli
|
|
CCL11 or chemokine (C-C motif) ligand 11 is a member of the chemokine (C-C motif) ligand family. Chemokin (C-C motif) ligand 11 is a member of the chemokine family. There are four members of the chemokine family: C-C kemokines, C kemokines, CXC kemokines and CX3C kemokines. The C-C kemokines have two cysteines nearby the amino terminus. There have been at least 27 distinct members of this subgroup reported for mammals, called C-C chemokine ligands (CCL)-1 to 28. Chemokines are a family of small ... |
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TMPY-04396
|
C-ABL/ABL1 Protein, Human, Recombinant (GST)
v-abl,ABL,JTK7,ABL proto-oncogene 1, non-receptor tyrosine k...
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Human
|
Baculovirus Insect Cells
|
|
c-Abl belongs to the class of tyrosine kinases and is the prototype of a subfamily which includes two members, c-Abl and Arg (Abl-related gene). Both proteins are localized at the cell membrane, actin cytoskeleton and cytosol, and c-Abl is present in the nucleus as well. c-Abl is a non-receptor tyrosine kinase that participates in multiple signaling pathways linking the cell surface, cytoskeleton, and the nucleus. Recent in vitro studies have also linked c-Abl to amyloid-beta-induced toxicity an... |
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TMPH-03764
|
YAP1 Protein, Human, Recombinant (His)
YAP1-2gamma,YAP2L,YAP65
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Human
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P. pastoris (Yeast)
|
|
Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1,... |
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TMPH-03754
|
NAV1 Protein, Human, Recombinant (His)
NAV1,Steerin-1,Pore membrane and/or filament-interacting-lik...
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Human
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E. coli
|
|
May be involved in neuronal migration. |
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TMPK-00988
|
ECSCR Protein, Mouse, Recombinant (hFc)
ECSCR,ARIA,ECSM2
|
Mouse
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HEK293 Cells
|
|
Endothelial cell-specific chemotaxis receptor (ECSCR) is a cell surface protein expressed by blood endothelial cells with roles in endothelial cell migration and signal transduction. Zebrafish ecscr is expressed in angioblasts and in axial vessels during angioblast migration and vasculogenesis. Morpholino-directed ecscr knockdown resulted in defective angioblast migration in the posterior lateral plate mesoderm, a process known to depend on vascular endothelial-derived growth factor (VEGF). ECSC... |
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TMPK-00978
|
ECSCR Protein, Human, Recombinant (hFc)
ECSM2,ECSCR,ARIA
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Human
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HEK293 Cells
|
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Endothelial cell-specific chemotaxis receptor (ECSCR) is a cell surface protein expressed by blood endothelial cells with roles in endothelial cell migration and signal transduction. Zebrafish ecscr is expressed in angioblasts and in axial vessels during angioblast migration and vasculogenesis. Morpholino-directed ecscr knockdown resulted in defective angioblast migration in the posterior lateral plate mesoderm, a process known to depend on vascular endothelial-derived growth factor (VEGF). ECSC... |
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TMPY-03261
|
CNPY2 Protein, Human, Recombinant (His)
canopy FGF signaling regulator 2,HP10390,ZSIG9,MSAP,TMEM4
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Human
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HEK293 Cells
|
|
CNPY2 is a novel MIR-interacting protein that enhances neurite outgrowth and increases myosin regulatory light chain. CNPY2 enhances migration of C6 glioma cells through phosphorylation of the myosin regulatory light chain. It is expressed in different tissues, including brain. Overexpression of CNPY2 enhanced the motility of glioma cells measured in matrigel invasion chambers and using a scratch assay. Downregulation of CNPY2 by RNA interference significantly decreased glioma cell migration and... |
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TMPH-01297
|
DDR1 Protein, Human, Recombinant (aa 21-417, His)
EDDR1,MCK-10,Epithelial discoidin domain-containing receptor...
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Human
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HEK293 Cells
|
|
Tyrosine kinase that functions as cell surface receptor for fibrillar collagen and regulates cell attachment to the extracellular matrix, remodeling of the extracellular matrix, cell migration, differentiation, survival and cell proliferation. Collagen binding triggers a signaling pathway that involves SRC and leads to the activation of MAP kinases. Regulates remodeling of the extracellular matrix by up-regulation of the matrix metalloproteinases MMP2, MMP7 and MMP9, and thereby facilitates cell... |
|
TMPH-02922
|
SRPX2 Protein, Mouse, Recombinant (His & Myc)
Sushi repeat-containing protein SRPX2,Srpx2
|
Mouse
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Baculovirus Insect Cells
|
|
Acts as a ligand for the urokinase plasminogen activator surface receptor. Plays a role in angiogenesis by inducing endothelial cell migration and the formation of vascular network (cords). Involved in cellular migration and adhesion. Increases the phosphorylation levels of FAK. Interacts with and increases the mitogenic activity of HGF. Promotes synapse formation. Required for ultrasonic vocalizations. SRPX2 Protein, Mouse, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N... |
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TMPJ-00157
|
CD82 Protein, Human, Recombinant (hFc)
Tetraspanin-27,KAI1,ST6,TSPAN27,TSPAN274F9,CD82 molecule,Tsp...
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Human
|
HEK293 Cells
|
|
CD82 antigen, also known as Kai-1, is a widely expressed palmitoylated molecule of the tetraspanin superfamily. KAI1/CD82 is localized on cell membrane and form interactions with other tetraspanins, integrins and chemokines which are respectively responsible for cell migration, adhesion and signaling. CD82/Kai-1 is a component of the promiscuous TIMP-1 interacting protein complex on the cell surface of human adenocarcinoma cells and gives insight into tumorigenic metastatic potential. CD82/Kai-1... |
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TMPH-02831
|
PLET1 Protein, Mouse, Recombinant (His & SUMO)
Plet1,Placenta-expressed transcript 1 protein,Antigen mAgK11...
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Mouse
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E. coli
|
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Modulates leading keratinocyte migration and cellular adhesion to matrix proteins during a wound-healing response and promotes wound repair. May play a role during trichilemmal differentiation of the hair follicle. |
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TMPH-01207
|
DOCK8 Protein, Human, Recombinant (His)
DOCK8,Dedicator of cytokinesis protein 8
|
Human
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P. pastoris (Yeast)
|
|
Guanine nucleotide exchange factor (GEF) which specifically activates small GTPase CDC42 by exchanging bound GDP for free GTP. During immune responses, required for interstitial dendritic cell (DC) migration by locally activating CDC42 at the leading edge membrane of DC. Required for CD4(+) T-cell migration in response to chemokine stimulation by promoting CDC42 activation at T cell leading edge membrane. Is involved in NK cell cytotoxicity by controlling polarization of microtubule-organizing c... |
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TMPH-01602
|
LAMA5 Protein, Human, Recombinant (His & SUMO)
LAMA5,Laminin subunit alpha-5,Laminin-15 subunit alpha,Lamin...
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Human
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E. coli
|
|
Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. |
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TMPH-02830
|
PLET1 Protein, Mouse, Recombinant (His)
Plet1,Placenta-expressed transcript 1 protein,Antigen mAgK11...
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Mouse
|
Baculovirus Insect Cells
|
|
Modulates leading keratinocyte migration and cellular adhesion to matrix proteins during a wound-healing response and promotes wound repair. May play a role during trichilemmal differentiation of the hair follicle. |
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TMPH-01228
|
DPYSL3 Protein, Human, Recombinant (His)
ULIP-1,DRP-3,Dihydropyrimidinase-related protein 3,DPYSL3,Un...
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Human
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E. coli
|
|
Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration. |
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TMPH-02623
|
DOCK8 Protein, Mouse, Recombinant (His)
Dedicator of cytokinesis protein 8,DOCK8
|
Mouse
|
P. pastoris (Yeast)
|
|
Guanine nucleotide exchange factor (GEF) which specifically activates small GTPase CDC42 by exchanging bound GDP for free GTP. During immune responses, required for interstitial dendritic cell (DC) migration by locally activating CDC42 at the leading edge membrane of DC. Required for CD4(+) T-cell migration in response to chemokine stimulation by promoting CDC42 activation at T cell leading edge membrane. Is involved in NK cell cytotoxicity controlling polarization of microtubule-organizing cent... |
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TMPH-02923
|
SRPX2 Protein, Mouse, Recombinant (His & Myc & SUMO)
Srpx2,Sushi repeat-containing protein SRPX2
|
Mouse
|
E. coli
|
|
Acts as a ligand for the urokinase plasminogen activator surface receptor. Plays a role in angiogenesis by inducing endothelial cell migration and the formation of vascular network (cords). Involved in cellular migration and adhesion. Increases the phosphorylation levels of FAK. Interacts with and increases the mitogenic activity of HGF. Promotes synapse formation. Required for ultrasonic vocalizations. SRPX2 Protein, Mouse, Recombinant (His & Myc & SUMO) is expressed in E. coli expression syste... |
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TMPH-02622
|
DOCK8 Protein, Mouse, Recombinant (E. coli, His)
DOCK8,Dedicator of cytokinesis protein 8
|
Mouse
|
E. coli
|
|
Guanine nucleotide exchange factor (GEF) which specifically activates small GTPase CDC42 by exchanging bound GDP for free GTP. During immune responses, required for interstitial dendritic cell (DC) migration by locally activating CDC42 at the leading edge membrane of DC. Required for CD4(+) T-cell migration in response to chemokine stimulation by promoting CDC42 activation at T cell leading edge membrane. Is involved in NK cell cytotoxicity controlling polarization of microtubule-organizing cent... |
|
TMPJ-00365
|
GAS6 Protein, Human, Recombinant (Avi & His), Biotinylated
AXLLG,Growth arrest-specific protein 6,AXL receptor tyrosine...
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Human
|
HEK293 Cells
|
|
Human Growth arrest-specific protein 6 (GAS6) is ligand for tyrosine-protein kinase receptors AXL, TYRO3 and MER whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification by preventing apoptosis, optimal cytokine signaling during human natural killer cell development, hepatic regeneration, gonadotropin-releasing hormone neuron survival and migration, plat... |
|
TMPJ-00587
|
NRCAM Protein, Human, Recombinant (hFc)
gCAM-related cell adhesion molecule,hBravo,Ng-CAM-related,Nr...
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Human
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HEK293 Cells
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Neuronal cell adhesion molecule(NRCAM) is a single-pass type I membrane protein ,containing 5 fibronectin type-III domains and 6 Ig-like C2-type (immunoglobulin-like) domains.It belongs to the immunoglobulin superfamily. NrCAM is engaged in such biological processes as axonal fasciculation, cell-cell adhesion, central nervous system development, clustering of voltage-gated sodium channels, neuron migration, positive regulation of neuron differentiation, regulation of axon extension, and synaptog... |
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TMPJ-00366
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GAS6 Protein, Human, Recombinant (hFc)
AXLLG,Gas6,GAS-6,AXLLGAXL stimulatory factor,growth arrest-s...
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Human
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HEK293 Cells
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GAS6 (Growth arrest-specific protein 6) is also known as AXL receptor tyrosine kinase ligand, AXLLG, is a multimodular protein that is up-regulated by a wide variety of cell types in response to growth arrest. Gas6 binds and induces signaling through the receptor tyrosine kinases Axl, Dtk, and Mer whose signaling is implicated in cell growth and survival, cell adhesion and cell migration. GAS6/AXL signaling plays a role in various processes such as endothelial cell survival during acidification ... |
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