381
117
23
1
87
15
Cat. No. | Product Name | ||
---|---|---|---|
L2130 | 抗癌细胞代谢库 | 1268 compounds | |
1268 种癌细胞代谢相关的生物活性小分子化合物的特有集合,用于肿瘤相关的研究以及抗肿瘤药物的筛选,用于高通量、高内涵筛选; | |||
L2560 | 代谢化合物库 | 2320 compounds | |
2320 种代谢途径相关的化合物,可用于高通量和高内涵筛选。 | |||
L2550 | 谷氨酰胺代谢化合物库 | 565 compounds | |
565 种谷氨酰胺代谢相关的分子,可以用于高通量和高内涵筛选; | |||
L5300 | 线粒体靶向库 | 812 compounds | |
812 种具有潜在或确定线粒体靶向活性的化合物,以促进针对线粒体的药物研究; | |||
L2501 | 人内源代谢化合物库 Plus | 1283 compounds | |
1283种内源性生物活性化合物的独特集合,用于高通量、高内涵筛选。 | |||
L1900 | 抗糖尿病库 | 683 compounds | |
683 种生物活性小分子化合物; | |||
L2540 | 肠道微生物代谢化合物库 | 614 compounds | |
614 种肠道微生物代谢物的集合,可以用于高通量和高内涵筛选; | |||
L5100 | 含氟化合物库 | 574 compounds | |
574 个含氟化合物的独特集合,可用于高通量筛选和高内涵筛选; | |||
L5500 | 毒性化合物库 | 262 compounds | |
262 个细胞毒性化合物的特有集合,可用于高通量、高内涵筛选。 | |||
L1510 | 核受体化合物库 | 531 compounds | |
531 个核受体作用化合物的独特集合,可用于高通量筛选和高内涵筛选; | |||
L3200 | 自噬库 | 1248 compounds | |
1248 种细胞自噬相关的生物活性小分子化合物的特有集合,用于自噬相关的研究,用于高通量、高内涵筛选; | |||
L9610 | 环肽库 | 80 compounds | |
80 种环肽分子,可用于高通量和高内涵筛选; | |||
L1600 | 激酶抑制剂库 | 2720 compounds | |
2720 种激酶抑制剂/调节剂的独特集合,用于特定靶向激酶,可用于高通量筛选和高内涵筛选; | |||
L7000 | 活性脂质化合物库 | 385 compounds | |
385 种生物活性小分子化合物,用于高通量、高内涵筛选; | |||
L6600 | 胃肠炎天然产物库 | 219 compounds | |
219 种胃肠炎相关的生物活性小分子化合物的特有集合,用于高通量、高内涵筛选; | |||
L1120 | AMPK靶向分子库 | 80 compounds | |
80 个靶向AMPK 的分子集合,可用于高通量和高内涵筛选; | |||
L2500 | 人内源代谢化合物库 | 499 compounds | |
499 种内源性生物活性化合物的独特集合,用于高通量、高内涵筛选; | |||
L2510 | 脂代谢化合物库 | 492 compounds | |
492 个脂代谢相关的化合物集合,可用于高通量和高内涵筛选; | |||
L9600 | 多肽分子库 | 791 compounds | |
791 种多肽类分子,可用于多肽药物开发及信号转导通路和作用机制研究; | |||
L2520 | 糖代谢化合物库 | 702 compounds | |
702 种糖代谢相关的化合物,可用于高通量和高内涵筛选; | |||
L7100 | 抗肥胖化合物库 | 2247 compounds | |
2247 个抗肥胖化合物的独特集合,可用于高通量筛选和高内涵筛选; | |||
L6400 | 海洋天然产物库 | 144 compounds | |
144 种海洋来源的单体化合物,是药物开发、药理研究等领域的有力工具; | |||
L7110 | 抗高血压化合物库 | 678 compounds | |
678 种高血压相关的小分子,用于高通量和高内涵筛选; |
Cat. No. | Product Name | Form | Specificity Of Inhibition |
---|---|---|---|
C0048 |
Deacetylase Inhibitor Cocktail (100× in 70% DMSO)
去乙酰化酶抑制剂 Cocktail(100× in 70% DMSO) |
Solution (100× in 70% DMSO) | Class I/II/III HDAC |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T0940 |
Acesulfame Potassium
|
Others | Others |
Acesulfame potassium 是一种人造甜味剂,长期使用会影响认知功能,可能改变小鼠的神经代谢功能。 | |||
TD0093 |
Oil Red O
|
Others | Others |
Oil Red O 用于制备染色溶液,可用于检测组织学冷冻切片中的脂质。 | |||
T8337 |
Nequinate
|
Xanthine Oxidase; Parasite | Metabolism; Microbiology/Virology |
Nequinate 是一种喹啉化合物,是一种抗球虫剂,可预防球虫病。它抑制黄嘌呤氧化还原酶活性。 | |||
T9491 |
Pyraclostrobin
|
Antibacterial; Antifungal | Microbiology/Virology |
Pyraclostrobin 是一种球果苷杀菌剂,可诱导 3T3-L1 细胞内甘油三酯的积累,还可抑制真菌和哺乳动物细胞的线粒体复合物 III 。 | |||
T8511 |
TM38837
|
Cannabinoid Receptor | GPCR/G Protein |
TM38837 是外周选择性大麻素受体1型受体拮抗剂。它减少精神病副作用的倾向。它对大脑的渗透率有限,以降低或防止 CNS 不良反应,并保留潜在的抗肥胖作用。 | |||
T7092 |
NADPH tetrasodium salt
|
Others; Ferroptosis; Endogenous Metabolite | Apoptosis; Metabolism; Others |
NADPH tetrasodium salt 是电子受体烟酰胺腺嘌呤二核苷酸磷酸的还原形式,在各种生物反应中充当电子供体。NADPH tetrasodium salt 也是一种内源性铁死亡抑制剂。 | |||
T9609 |
GRK5-IN-2
|
GRK | GPCR/G Protein |
GRK5-IN-2 是基于吡啶的双环化合物,抑制 G 蛋白偶联受体激酶 5 。它调节胰岛素的表达和/或释放,在代谢疾病中有研究价值。 | |||
T19857 |
Glyphosate
Atila,Lancer,Folusen,草甘膦 |
Apoptosis; Autophagy | Apoptosis; Autophagy |
Glyphosate (Atila) 是氨基酸甘氨酸的衍生物。它是一种除草剂,靶向并阻断植物合成芳香氨基酸所必需的莽草酸途径。 | |||
T2216 |
Entacapone
OR-611,恩他卡朋 |
Transferase | Metabolism |
Entacapone (OR-611) 是可逆的、具有口服活性的、外周作用的儿茶酚-O-甲基转移酶抑制剂。它对大鼠脑、红细胞和肝脏 COMT 有抑制作用。它对 COMT 的选择性优于其他儿茶酚胺代谢酶。它抑制 FTO 去甲基化活性,可用于研究代谢紊乱。它可用于研究帕金森病。 | |||
T12931 |
SLC13A5-IN-1
|
Stearoyl-CoA Desaturase (SCD) | Metabolism |
SLC13A5-IN-1 是柠檬酸钠协同转运蛋白 (SLC13A5)选择性抑制剂,在 HepG2 细胞中阻断 14C-柠檬酸盐摄取的 IC50 : 0.022 μM。 | |||
T12998 |
SR10067
|
Others; Autophagy | Autophagy; Others |
SR10067 是选择性的Rev-Erbα/β的激动剂,其对Rev-Erbβ 和Rev-Erbα 的IC50分别为 160 nM 和 170 nM。SR10067可以透过大脑的。SR10067具有抗焦虑活性。 | |||
T7879 |
TASP0415914
|
Akt; PI3K | Cytoskeletal Signaling; PI3K/Akt/mTOR signaling |
TASP0415914 是一种具有口服活性的 PI3Kγ抑制剂,其 IC50=29 nM。它是一种 Akt 抑制剂,其 IC50=294 nM。它可用于研究炎症性疾病。 | |||
T21679 |
4'-bromo-Resveratrol
|
Sirtuin | Chromatin/Epigenetic; DNA Damage/DNA Repair |
4'-Bromo-resveratrol 是Sirtuin-1和Sirtuin-3的双重抑制剂。它通过线粒体代谢重编程,使黑色素瘤细胞的生长受到抑制。它通过代谢重编程、影响细胞周期以及细胞凋亡的信号传导,使其在黑色素瘤细胞中发挥抗增殖作用。 | |||
T0413 |
Cinromide
醒隆酰胺,trans-3-Bromo-N-ethylcinnamamide |
Others | Others |
Cinromide (trans-3-Bromo-N-ethylcinnamamide) 是抗惊厥药,能够抑制上皮中性氨基酸转运蛋白 B0AT1 (SLC6A19),其 IC50=0.5 μM。 | |||
T7656 |
Apelin-13
|
||
Apelin-13 是存在于中枢和外周神经系统由13个氨基酸组成的多肽序列,是 G 蛋白偶联受体angiotensin II protein J (APJ) 的内源性配体,对 APJ 的 EC50 值为 0.37 nM。Apelin-13 具有扩张血管和降压活性,可用于研究 2 型糖尿病综合征。 | |||
T6574 |
Lumiracoxib
Prexige,罗美昔布,COX-189 |
COX | Immunology/Inflammation; Neuroscience |
Lumiracoxib (Prexige) 是强选择性有口服活性的 COX-2抑制剂,Ki 值为 0.06 μM。它是非选择性非甾体抗炎试剂,具有抗炎和解热活性,可用于骨关节炎和骨癌研究。 | |||
T0686 |
Orlistat
Ro-18-0647,奥利司他,Tetrahydrolipstatin |
Apoptosis; Others; Fatty Acid Synthase | Apoptosis; Metabolism; Others |
Orlistat (Tetrahydrolipstatin) 是一种不可逆的胰腺和胃脂肪酶抑制剂,也是一种脂肪酸合成酶抑制剂,可研究肥胖症,具有抗动脉粥样硬化作用。 | |||
T10035 |
10,12-Tricosadiynoic acid
TDA,TCDA |
Acyltransferase | Metabolism |
10,12-Tricosadiynoic acid 是一种口服有效的酰基辅酶 A 氧化酶-1 (ACOX1) 抑制剂,具有高特异性,选择性,高亲和力的特点。10,12-Tricosadiynoic acid 可改善线粒体脂质和 ROS 代谢,在高脂饮食或肥胖引起的代谢性疾病中有研究的价值。 | |||
T5427 |
GSK1940029
SCD inhibitor 1 |
Dehydrogenase; Stearoyl-CoA Desaturase (SCD) | Metabolism |
GSK1940029 (SCD inhibitor 1) 是酰基-辅酶A 去饱和酶 (SCD) 抑制剂。 | |||
T19700 |
IBC 293
IBC293,1-异丙基-1H-1,2,3-苯并噻唑-5-羧酸,IBC-293 |
GPR | Endocrinology/Hormones; GPCR/G Protein |
IBC 293 对 GPR109B 的选择性高于烟酸受体 GPR109A。 IBC 293 是 GPR109B 的高选择性激动剂,GPR109B 是一种在脂肪细胞中表达的人类孤儿 G 蛋白偶联受体。 | |||
T0773 |
Febuxostat
非布索坦,TMX 67,非布司他,TEI 6720 |
ROS; Xanthine Oxidase | Immunology/Inflammation; Metabolism |
Febuxostat (TEI 6720) 是一种选择性黄嘌呤氧化酶(XO)抑制剂,Ki=0.6 nM。 | |||
T14364 |
AZ-Dyrk1B-33
3-(2-Methyl-4-pyrimidinyl)-1-(phenylmethyl)-1H-pyrrolo[2,3-c]pyridine |
DYRK | Cell Cycle/Checkpoint; Tyrosine Kinase/Adaptors |
AZ-Dyrk1B-33 (3-(2-Methyl-4-pyrimidinyl)-1-(phenylmethyl)-1H-pyrrolo[2,3-c]pyridine) 是高选择性的Dyrk1B 激酶抑制剂,其IC50=7 nM。 | |||
T22276 |
Bis(maltolato)oxovanadium(IV)
双(麦芽醇)氧钒(IV),BMOV,Bis maltolato oxovanadium,Bis(maltolato)oxovanadium (IV),bis maltolato oxo vanadium,Bis(maltolato)oxovanadium (IV) |
Phosphatase; Others | Metabolism; Others |
Bis(maltolato)oxovanadium(IV) (BMOV) 是一种有效的胰岛素增敏剂,也是一种有效的、竞争性的、可逆的、口服具有活性的光谱蛋白酪氨酸磷酸酶 (PTP) 抑制剂。它抑制HCPTPA,PTP1B,HPTPβ和SHP2的IC50分别为 126 nM,109 nM,26 nM 和 201 nM。 | |||
T9733 |
PAL-4
1H-1,2,4-Triazol-5-amine, 3-[[(4-chlorophenyl)methyl]thio]-1-[(2,3-dihydro-5-benzofuranyl)sulfonyl]- |
Others | Others |
PAL-4刺激 LYPLAL1 的活性, 一种特征不佳的丝氨酸水解酶,与人类代谢特征具有复杂的遗传联系。 | |||
T0418 |
Allylthiourea
阿利硫脲,N-Allylthiourea,Thiosinamine,烯丙基硫脲 |
MAO; Reactive Oxygen Species | Immunology/Inflammation; Metabolism; Neuroscience; NF-κB |
Allylthiourea (Thiosinamine) 是一种代谢抑制剂,专门抑制氨氧化。 | |||
T15448 |
GW-1100
GW 1100,GW1100 |
GPR | Endocrinology/Hormones; GPCR/G Protein |
GW-1100是选择性的 GPR40 和 FFAR1 拮抗剂,可用于研究糖尿病和代谢疾病。 | |||
T23209 |
Qc1
Qc 1 |
Dehydrogenase | Metabolism |
Qc1是苏氨酸脱氢酶(TDH)的抑制剂,可用于有关代谢性疾病的研究。 | |||
T5411 |
PDE10-IN-1
SEP-0372814 |
PDE | Metabolism |
PDE10-IN-1 (SEP-0372814) 是一种高效的 PDE10抑制剂。 | |||
T22832 |
H-8 hydrochloride
|
PKA | Tyrosine Kinase/Adaptors |
H-8 hydrochloride 是一种具有可逆性和 ATP 竞争性的 PKA 抑制剂。可用研究代谢疾病。 | |||
T11758 |
KI696 isomer
|
Nrf2 | Immunology/Inflammation |
KI696 isomer 是 KI696 的异构体,是一种亲和力较低的探针,可用于研究免疫和代谢疾病。 | |||
T26701 |
AZ12216052
AZ 12216052,AZ-12216052 |
GPR | Endocrinology/Hormones; GPCR/G Protein |
AZ12216052 是一种 GRP8 拮抗剂,具有抗焦虑和抗炎活性,可用于研究肥胖和代谢紊乱。 | |||
T27019 |
PSB-CB5
CID-85469571,GPR18-IN-32 |
GPR | Endocrinology/Hormones; GPCR/G Protein |
PSB-CB5 (GPR18-IN-32)2 是一种 GRP18 拮抗剂,具有抗炎活性,可用于研究肥胖和代谢紊乱。 | |||
T13673 |
EGTA-AM
EGTA Acetoxymethyl ester |
Others | Others |
EGTA-AM (EGTA Acetoxymethyl ester) 是一种钙离子螯合剂, 是一种膜渗透形式的 EGTA,是早发型子痫前期和晚发性子痫前期的代谢生物学标志物。 | |||
T11741 |
KAN0438757
|
Glucokinase; Autophagy | Autophagy; Metabolism |
KAN0438757 是一种选择性强效的代谢激酶 PFKFB3 抑制剂,IC50值为 0.19 μM。 | |||
T31611 |
Eldacimibe
WAY-ACA-147,UNII-4PBL76O2G8,ANA 147,ACA 147 |
Acyltransferase | Metabolism |
Eldacimibe (WAY-ACA-147) 是一种ACAT2抑制剂,可用于治疗心血管疾病和内分泌与代谢疾病,研究动脉粥样硬化和高胆固醇血症。 | |||
T21457 |
Carbazeran
UK-31557,UK31,557,UK-31,557,UK31557,UK 31557,卡巴折伦,UK 31,557 |
PDE | Metabolism |
Carbazeran (UK-31,557) 是 PDE2 和 PDE3 的抑制剂,可用于代谢疾病的研究。 Carbazeran 在体内显示出正性肌力和变时性作用 (EC50 = 100 μM)。 | |||
T39350 |
Sebetralstat
KVD900 |
Others | Others |
Sebetralstat (KVD900) 是一种血浆激肽释放酶抑制剂,可用于代谢性疾病的研究。 | |||
T34385 |
Ronacaleret HCl
SB 751689,SB 751689A,SB-751689A,SB-751689,SB751689A,SB751689 |
CaSR | GPCR/G Protein |
Ronacaleret HCl (SB-751689) 是一种小分子 CaSR 拮抗剂,可用于治疗内分泌与代谢疾病、皮肤和肌肉骨骼疾病。 | |||
T60908 |
SARM1-IN-2
|
Others | Others |
SARM1-IN-2 是一种有效的 SARM1 抑制剂,可用于研究代谢系统和神经系统相关疾病。 | |||
T19626 |
LHW090-A7
(ALPHAS)-3'-氯-ALPHA-[[(1S)-2-乙氧基-1-甲基-2-氧代乙基]氨基][1,1'-联苯]-4-丙酸 |
Neprilysin | Metabolism |
LHW090-A7 是一种中性肽链内切酶 (NEP) 抑制剂,是一种负责脑啡肽代谢失活的酶。 | |||
T11978 |
McN3716
NSC359682,Methyl palmoxirate |
Mitochondrial Metabolism; CPT | Metabolism |
McN3716 是一种肉碱棕榈酰转移酶 I (CPT-1) 抑制剂,可用于研究代谢疾病。 | |||
T14839 |
Butyrolactone 3
MB-3,MB3,MB 3 |
Epigenetic Reader Domain; Antibacterial | Chromatin/Epigenetic; Microbiology/Virology |
Butyrolactone 3 (MB-3) 是一种具有选择性和高效性的组蛋白乙酰转移酶 Gcn5 抑制剂,对 CBP 亲和力较弱。Butyrolactone 3 具有抗菌活性,可用于癌症、代谢性疾病和和神经系统疾病。 | |||
T0068 |
Fluphenazine dihydrochloride
氟奋乃静盐酸盐,Prolixin,盐酸氟奋乃静,Fluphenazine hydrochloride |
Dopamine Receptor | GPCR/G Protein; Neuroscience |
Fluphenazine dihydrochloride (Prolixin) 是一种多巴胺受体D1/D2抑制剂。 | |||
T6112 |
Doxercalciferol
TSA 840,度骨化醇,Hectorol,1.alpha.-Hydroxyvitamin D2,1α-hydroxyvitamin D2 |
Others | Others |
Doxercalciferol (TSA 840) 是一种维生素 D2 类似物,是一种维生素 D 受体激活剂,能够阻碍肾病的进程。 | |||
T61144 |
Hepcidin antagonist-1
|
Others | Others |
Hepcidin antagonist-1 是一种铁调素拮抗剂。Hepcidin antagonist-1 可用于研究像缺铁疾病和贫血类的代谢紊乱。 | |||
T68132L |
Quercetin-3'-o-phosphate TEA
Quercetin-3'-o-phosphate TEA(1111616-69-3 Free base),3'-quercetin phosphate TEA,Quercetin 3'-phosphate TEA |
Adenosine Receptor | GPCR/G Protein; Neuroscience |
Quercetin-3'-o-phosphate TEA (Quercetin 3'-phosphate TEA)是一种腺苷 A 受体拮抗剂,可用来预防和治疗代谢紊乱。 | |||
T77784 |
WAY-297848
|
Glucokinase | Metabolism |
WAY-297848 是一种新型的 glucokinase 激活剂,可用于预防或治疗高血糖、糖尿病、肥胖症、血脂异常和代谢综合征。 | |||
T40287 |
FATP1-IN-2
|
Others | Others |
FATP1-IN-2 是一种脂肪酸转运蛋白1 (FATP1) 抑制剂,具有口服活性,可用于研究肥胖和代谢疾病。 | |||
T71321 |
(S)-VU0637120
|
Others | Others |
(S)-VU0637120 是一种选择性的神经肽 Y(4)R变构拮抗剂,可用于研究代谢疾病。 | |||
T74041 |
GDP-L-fucose
|
Endogenous Metabolite | Metabolism |
GDP-L-fucose 是一种广泛存在与真菌和植物中的核苷酸糖,参与从头代谢途径和次要的补救代谢途径。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T4862 |
Oxaloacetic acid
|
Endogenous Metabolite | Metabolism |
Oxaloacetic acid 是一种代谢中间体,涉及多种途径,如葡萄糖异生、柠檬酸循环、乙醛酸循环、尿素循环、氨基酸合成和脂肪酸合成。 | |||
T3836 |
Eudesmin
|
MAPK; S6 Kinase | MAPK; PI3K/Akt/mTOR signaling |
Eudesmin 通过抑制S6K1信号通路来干扰成脂分化,具有抗肿瘤、抗炎和抗菌活性。 | |||
T8392 |
L(+)-Asparagine monohydrate
|
Endogenous Metabolite | Metabolism |
L(+)-Asparagine monohydrate 是一种非必需氨基酸,参与组织细胞功能的神经和代谢调节。 | |||
T13795 |
Nicotinamide riboside
|
Sirtuin | Chromatin/Epigenetic; DNA Damage/DNA Repair |
Nicotinamide riboside 是维生素 B3 的来源,可以增强氧化代谢并防止高脂肪饮食诱导的代谢异常。它是具有口服活性的 NAD+的前体,增加 NAD+水平并激活SIRT1和SIRT3,可用于研究阿尔茨海默氏病的认知退化。 | |||
T4733 |
Sucrose
D(+)-Sucrose,D-(+)-Saccharose,蔗糖 |
Others; Endogenous Metabolite | Metabolism; Others |
Sucrose (D-(+)-Saccharose) 是一种二糖,由果糖和葡萄糖组成。Sucrose 能够应用于一些动物模型,包括代谢性疾病、偏食、肥胖、糖尿病等。 | |||
T0846 |
L-Carnitine
L(-)-Carnitine,Levocarnitine,左旋肉碱 |
Endogenous Metabolite; Fatty Acid Synthase | Metabolism |
L-Carnitine (L(-)-Carnitine) 是一种人内源性分子,在人体内以蛋氨酸和赖氨酸为底物进行生物合成,并参与脂肪酸代谢。L-Carnitine 将长链脂肪酰辅酶A 转运到线粒体。L-Carnitine 能够改善许多先天性代谢错误的代谢失衡。 | |||
T2S0271 |
Voacamine
老刺木胺,Voacanginine |
Cannabinoid Receptor; P-gp | GPCR/G Protein; Membrane transporter/Ion channel; Neuroscience |
Voacamine (Voacanginine) 是非洲马铃果中的一种吲哚生物碱,可抑制多药耐药肿瘤细胞中的 P-糖蛋白作用,具有强效的大麻素 CB1受体拮抗活性。 | |||
T2869 |
Emodin
Frangula emodin,大黄素 |
SARS-CoV; Casein Kinase; Autophagy | Autophagy; Metabolism; Microbiology/Virology; Stem Cells |
Emodin (Frangula emodin) 是蒽醌衍生物,有抗SARS-CoV 作用。它阻断 SARS 冠状病毒刺突蛋白和血管紧张素转化酶 2 的相互作用。它抑制酪蛋白激酶 2 ,具有抗炎和抗癌作用。它可改善饮食诱导的肥胖小鼠的代谢紊乱。 | |||
T19081 |
1,3-Dithiane
1,3-Dithian,M-DITHIANE,1,3-Dithiacyclohexane,1,3-二噻烷 |
Anti-infection; Endogenous Metabolite; Antibacterial | Metabolism; Microbiology/Virology |
1,3-Dithiane (1,3-Dithian) 是一种受保护的甲醛阴离子等价物,可用作有用的标记合成子。它是在煮熟的牛肉提取物中发现的含硫美拉德反应产物 。 | |||
T6220 |
Nicotinamide riboside chloride
烟酰胺核糖氯酸盐,烟酰胺核苷 |
Sirtuin; Endogenous Metabolite | Chromatin/Epigenetic; DNA Damage/DNA Repair; Metabolism |
Nicotinamide riboside Chloride 是维生素 B3 的来源,可以增强氧化代谢并防止高脂肪饮食诱导的代谢异常。它是具有口服活性的 NAD+的前体,增加 NAD+水平并激活SIRT1和SIRT3,可用于研究阿尔茨海默氏病的认知退化。 | |||
T4S0554 |
Theaflavine-3,3'-digallate
TFBG,theaflavin digallate,3,3’-二没食子酸酯茶黄素 |
Others | Others |
Theaflavine-3,3'-digallate (theaflavin digallate) 和乳酸一起可以减少单纯疱疹病毒的传播。 | |||
TN2121 |
3,5,7,3′,4′-Pentamethoxyflavone
栎精-3,5,7,3',4'-五甲醚,槲皮素3,5,7,3',4'-五甲基醚,Quercetin 3,5,7,3,4-pentamethyl ether |
Others | Others |
3,5,7,3′,4′-Pentamethoxyflavone (Quercetin 3,5,7,3,4-pentamethyl ether) 是一种分离自小花山奈中的多甲氧基黄酮。在分化早期,它可以调控转录因子,促进 3T3-L1 前脂肪细胞形成脂肪。 | |||
T5588 |
cis,cis-Muconic acid
顺式-已二烯二酸,cis,cis-Muconate,cis,cis-2,4-Hexadienedioic acid |
Others | Others |
cis,cis-Muconic acid (cis,cis-2,4-Hexadienedioic acid) 是肺炎克雷伯菌的代谢中间体,是合成聚合物的重要单体,可以转化为己二酸和对苯二甲酸。它也是一种生物化学材料,可用于生产各种塑料和聚合物。它作为己二酸前体可用于合成 nylon-6,6。 | |||
T1688 |
Pregnanediol
5Beta-Pregnane-3Alpha,20alpha-Diol,孕甾二醇,Pregnandiol,孕二醇 |
Estrogen/progestogen Receptor; Endogenous Metabolite | Endocrinology/Hormones; Metabolism |
Pregnanediol (5Beta-Pregnane-3Alpha,20alpha-Diol) 是一种黄体酮的主要代谢物 (metabolite),能够通过尿液排出。它提供了一种间接测定体内孕激素水平的方法。 | |||
T3604 |
Sodium dichloroacetate
Sodium Dichloroacetate,DCA,bichloroacetic acid,二氯乙酸钠,Sodium dichloroacetate (DCA),二氯醋酸酯 |
Apoptosis; Dehydrogenase; Reactive Oxygen Species; PDK | Apoptosis; Immunology/Inflammation; Metabolism; NF-κB; PI3K/Akt/mTOR signaling |
Sodium dichloroacetate (DCA) 是一种肿瘤细胞线粒体中的代谢调节剂,一种丙酮酸脱氢酶激酶 (PDK) 抑制剂。Sodium dichloroacetate 具有抗肿瘤活性,可以降低肿瘤微环境中的乳酸,增加活性氧的产生并促进肿瘤细胞凋亡。 | |||
T3324 |
Lycorine
Galanthidine,Narcissine,石蒜碱,Amarylline,Belamarine,Licorine,番石榴碱 |
Apoptosis; Virus Protease; Antibacterial; AChR; Fatty Acid Synthase | Apoptosis; Metabolism; Microbiology/Virology; Neuroscience |
Lycorine (Narcissine) 是从金眼科植物科中提取的一种天然生物碱。它是一种具有口服活性的SCAP 抑制剂,Kd 值 15.24 nM。它也是黑色素瘤血管生成抑制剂,有用于前列腺癌和代谢疾病的研究潜力。 | |||
T19127 |
3-Phosphoglyceric acid
|
Others | Others |
3-Phosphoglyceric acid is a metabolic intermediate in both glycolysis and the Calvin cycle. It is involved in alveolar macrophage epigenetic regulation. | |||
T5264 |
Androsterone
5alpha-Androsterone,Androkinin,5α-Androstan-3α-ol-17-one,雄甾酮,雄酮 |
FXR; Endogenous Metabolite; Autophagy | Autophagy; Metabolism |
Androsterone 是睾酮的代谢产物,可以激活法尼醇 X 受体。 | |||
T7450 |
1-Phenylpropane-1,2-dione
1-Phenyl-1,2-propanedione,Acetyl benzoyl,1-苯基-1,2-丙二酮 |
Others | Others |
1-Phenylpropane-1,2-dione (Acetyl benzoyl) 是麻黄素生物碱的生物合成前体,分离自从嫩麻黄中。 | |||
T0529 |
Dulcite
Galactitol,Dulcitol,Euonymit,NSC 1944,D-Galactitol,Melampyrit,半乳糖醇 |
Endogenous Metabolite | Metabolism |
Dulcite (D-Galactitol) 是一种具有微甜味的糖醇,其是半乳糖的代谢分解产物。 | |||
TN7068 |
Sinomenine N-oxide
|
Others | Others |
Sinomenine N-oxide 是青藤碱循环代谢机制的主要代谢产物之一。 | |||
T5071 |
4-Methyl-2-oxopentanoic acid
4-甲基-2-氧代戊酸,4-Methyl-2-oxovaleric acid |
Others; Endogenous Metabolite | Metabolism; Others |
4-Methyl-2-oxopentanoic acid 是一种非正常代谢物,是一种神经毒素和代谢毒素。 | |||
T65172 |
Flavin adenine dinucleotide
FAD |
Endogenous Metabolite | Metabolism |
Flavin adenine dinucleotide (FAD) 是一种氧化还原辅因子,是蛋白质的辅基,参与机体多种代谢反应。 | |||
T5788 |
XYLOBIOSE
|
IL Receptor; TNF | Apoptosis; Immunology/Inflammation |
Xylobiose 是一种木糖单体的二糖,单体之间具有 β-1, 4 键。 | |||
T3S0289 |
Araloside X
|
Calcium Channel | Membrane transporter/Ion channel; Metabolism |
Aralosides possess protective effect against experimental myocardial ischemia and infarction, the mechanism of myocardial protection may be attributed to the amelioration of FFA metabolic deterioration and membrane peroxidation induced by oxygen free radi | |||
TQ0190 |
D-Xylulose
|
Others; Endogenous Metabolite | Metabolism; Others |
D-xylulose 通过葡萄糖醛酸途径中的酶 NAD+ 连接的木糖醇脱氢酶从木糖醇转化,葡萄糖醛酸途径是哺乳动物中重要的木糖醇处理代谢途径。 | |||
T2799 |
(20S)-Protopanaxadiol
20-Epiprotopanaxadiol,20(S)-APPD,20 (S)-原人参二醇,原人参二醇 |
Apoptosis; Reactive Oxygen Species; P-gp | Apoptosis; Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism; Neuroscience; NF-κB |
(20S)-Protopanaxadiol (20-Epiprotopanaxadiol) 是人参皂甙的代谢产物,是一种凋亡诱导剂,抑制Akt 活性并诱导多种肿瘤细胞凋亡。 | |||
T8227 |
5'-Methylthioadenosine
Methylthioadenosine,5-脱氧-5-甲硫腺苷,5'-(Methylthio)-5'-deoxyadenosine,5'-Deoxy-5'-(methylthio)adenosine,5'-S-Methyl-5'-thioadenosine |
Endogenous Metabolite | Metabolism |
5'-Methylthioadenosine 是由 S-腺苷蛋氨酸在多胺合成过程中生成的核苷,通过抑制肿瘤细胞增殖、侵袭和诱导细胞凋亡来抑制肿瘤,同时控制肿瘤组织的炎症微环境。 | |||
TJS1159 |
Chrysosplenetin
猫眼草黄素,Chrysosptertin B |
P450; Ferroptosis; P-gp | Apoptosis; Membrane transporter/Ion channel; Metabolism; Neuroscience |
Chrysosplenetin 是青蒿和其他几种中草药中的一种多甲氧基化黄酮类天然产物,抑制 P-gp 活性并逆转由青蒿素诱导的上调的 P-gp 和 MDR1 水平。 | |||
TN1352 |
N-(3-Methoxybenzyl-(9z,12z)-octadecadienamide
12顺-亚油酸酰胺,(9Z,12Z)-N-(3-Methoxybenzyl)octadeca-9,12-dienamide,n-3-methoxybenzyl-9z-12z-octadecadienamide,玛卡酰胺杂质10 |
Drug Metabolite | Metabolism |
N-(3-Methoxybenzyl-(9z,12z)-octadecadienamide ((9Z,12Z)-N-(3-Methoxybenzyl)octadeca-9,12-dienamide) 是一种 Macamide 杂质,可能用于代谢疾病的研究。 | |||
TN3050 |
4'-Methoxyflavanone
|
Others | Others |
4'-Methoxyflavanone 是一种从天然 Isaria fumosorosea KCH J2中分离得到的黄酮类化合物,可用于研究代谢疾病和心血管疾病。 | |||
T19538 |
(R)-(-)-1,3-Butanediol
|
Endogenous Metabolite | Metabolism |
(R)-(-)-1,3-Butanediol 是一种新型生酮酯,可在短时间内快速增加健康成人循环中 r- 和 s-ß-羟基丁酸浓度,可用于研究代谢系统相关疾病。 | |||
T3O2784 |
Vitamin B6
维生素B6 |
Others | Others |
Vitamin B6 是人体某些辅酶的成分,参与多种代谢反应,特别是与氨基酸代谢有关。维生素B6在防治妊娠和放射病呕吐中的临床应用。 | |||
T1192 |
Protoporphyrin IX
PPIX,原卟啉,原卟啉IX |
Others; Endogenous Metabolite | Metabolism; Others |
Protoporphyrin IX (PPIX) 是一种四吡咯,是血红素、细胞色素 c 和叶绿素的代谢前体。 | |||
TN3820 |
Demethoxydeacetoxypseudolaric acid B
|
Others | Others |
Demethoxydeacetoxypseudolaric acid B 是 pseudolaric acid C2 的一种代谢物。 | |||
T5258 |
Dodecanedioic acid diammonium salt
十二烷二酸 二铵盐,1,10-Decanedicarboxylic acid diammonium salt |
Others | Others |
Dodecanedioic acid diammonium salt (1,10-Decanedicarboxylic acid diammonium salt) 是一种二元羧酸,它是水溶性的,并且参与了脂类和碳水化合物的代谢途径中间体。 | |||
T8073 |
Disodium succinate
丁二酸二钠,Sodium succinate |
Others | Others |
Disodium succinate (Sodium succinate) 是 Succinic acid 的盐形式。Succinic acid 是无氧代谢的发酵产物,也是三羧酸循环的中间产物。 | |||
T3S0381 |
Chrysophanol 8-O-glucoside
|
Serine Protease | Proteases/Proteasome |
Chrysophanol 8-O-glucoside 来自Rumex acetosa 根部,具有中等的弹性蛋白酶抑制特性。它具有温和的细胞毒性和抗糖尿病特性,能够在胰岛素刺激的葡萄糖转运途径中发挥代谢作用。 | |||
TMS2182 |
trans-Zeatinriboside
Ribosylzeatin,Zeatin Riboside,Trans-Zeatin Riboside,玉米素核苷 |
Others | Others |
trans-Zeatinriboside (Ribosylzeatin) 是一种细胞分裂素前体,是木质素导管中主要的长距离信号形式,能够调节叶片大小和分生组织活性相关形状。 | |||
T19262 |
D-Glucose 6-phosphate disodium salt
D-Glucose 6-phosphate disodium salt |
Endogenous Metabolite | Metabolism |
D-Glucose 6-phosphate disodium salt 广泛存在于生物提内的化合物,是葡萄糖第 6 号碳经过磷酸化后生成的分子,参与磷酸戊糖途径与糖酵解途径等体内多种多种代谢调节途径。 | |||
TN1475 |
Caulophyllogenin
Segetalic acid |
IL Receptor; TNF; PPAR; Immunology/Inflammation related | Apoptosis; DNA Damage/DNA Repair; Immunology/Inflammation; Metabolism |
Caulophyllogenin 是一种部分 PPARγ 激动剂 (EC50 = 12.6 μM),来源于 Kalopanax pictus (五加科) 的茎皮。 Caulophyllogenin 抑制促炎细胞因子分泌,可用于预防和治疗炎症性疾病、2 型糖尿病、肥胖和代谢综合征的研究。 | |||
T4A2456 |
Gamabufotalin
Gamabufagin,日本蟾蜍毒苷元 |
COX | Immunology/Inflammation; Neuroscience |
Gamabufotalin (Gamabufagin) 是一种蟾蜍甾烯,存在于蟾酥中。它稳定性高,毒性低,被广泛用于癌症的研究。 | |||
T1039 |
Choline chloride
Biocolina,Biocoline,Hepacholine,氯化胆碱 |
AChR | Neuroscience |
Choline chloride (Biocoline) 是一种必需营养素,可激活 α7 烟碱受体,具有抗炎、镇痛的活性。对动脉粥样硬化、神经系统疾病和肝脏疾病等具有影响。 | |||
T4238 |
Glycocyamine
乙酸胍,2-Guanidinoacetic acid,Guanidoacetic acid |
Others; Endogenous Metabolite | Metabolism; Others |
Glycocyamine (2-Guanidinoacetic acid) 是一种肌酸的前体,能够为鸟类的体内平衡提供能量,也能够成为食用精氨酸的替代物。 | |||
T10939L |
L-Cystathionine
L-胱硫醚,Cystathionine,ZINC1532680,L-(+)-Cystathionine,Cystathionine, L- |
Apoptosis; Endogenous Metabolite | Apoptosis; Metabolism |
L-Cystathionine (Cystathionine, L-) 是一种与含硫氨基酸的代谢条件有关的关键非蛋白质氨基酸。L-Cystathionine 可用于有关心血管保护的研究。 | |||
T2O2774 |
L-Asparagine
alpha-aminosuccinamic acid,L-天门冬氨酸,(-)-Asparagine,Asparamide,2-Aminosuccinamic acid,Asn,Altheine |
Endogenous Metabolite | Metabolism |
L-Asparagine (Asparamide) 是一种非必需氨基酸,可以参与神经和脑组织细胞功能的代谢控制。 | |||
T6S1880 |
Benzoylaconine
苯甲酰乌头原碱,Pikraconitin,Isaconitine,Benzoylaconitine |
Others | Others |
Benzoylaconine (Isaconitine) 是一种中药附子生物碱。 | |||
T6S1683 |
Demethoxycurcumin
Curcumin II,去甲氧基姜黄素,Desmethoxycurcumin,脱甲氧姜黄,Monodemethoxycurcumin |
Apoptosis; Antioxidant; Antibacterial; Autophagy | Apoptosis; Autophagy; Microbiology/Virology; oxidation-reduction |
Demethoxycurcumin (Desmethoxycurcumin) 是姜黄素的主要活性成分,有抗炎和抗癌作用。 | |||
T5231 |
2-Methylsuccinic acid
Pyrotartaric Acid,Methylbutanedioic acid,甲基丁二酸 |
Others; Endogenous Metabolite | Metabolism; Others |
2-Methylsuccinic acid (Pyrotartaric Acid) 是乙基丙二酸脑病的主要生化指标,是人体液中的正常代谢物。 | |||
T4734 |
Suberic acid
Octanedioic acid,1,8-Octanedioic acid,辛二酸 |
Others; Endogenous Metabolite | Metabolism; Others |
Suberic acid (1,8-Octanedioic acid) 被发现和肉毒碱-甲酰基-丙氨酸转位酶缺乏(丙二醇-羧基酶缺乏症)有关。 | |||
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Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPK-00369 |
HGF Protein, Human, Recombinant (hFc)
HGF,F-TCF,HGFB,SF,F-TCFB,肝细胞生长因子,DFNB39,Hepatopoietin-A,HPTA |
Human | HEK293 Cells |
Hepatocyte growth factor (HGF) is an important component of the pathophysiology of IR, with increased levels in most common IR conditions, including obesity. HGF has a role in the metabolic flux of glucose in different insulin sensitive cell types; plays a key role in β-cell homeostasis; and is capable of modulating the inflammatory response.HGF plays a central role in these metabolic disorders,HGF levels could be employed as a biomarker for disease status/progression, and HGF/c-Met signaling pa... | |||
TMPK-00942 |
DLK1 Protein, Mouse, Recombinant (His)
DLK1,DLK,pG2,secredeltin,ZOG,Pref1,DLK-1,FA1 |
Mouse | HEK293 Cells |
paternally inherited genetic defects of DLK1 were identified in four families with nonsyndromic CPP and a metabolic phenotype. DLK1 encodes a transmembrane protein that is important for adipose tissue homeostasis and neurogenesis and is located in the imprinted chromosome 14q32 region associated with Temple syndrome. DLK1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 30.9 kDa and the accession number is Q09163-1. | |||
TMPK-00639 |
Alkaline Phosphatase (Germ type) /ALPG Protein, Rat, Recombinant (His)
GCAP,ALP-1,Alkaline Phosphatase,ALPPL2,PLAP-like,ALPPL,ALPG,... |
Rat | HEK293 Cells |
Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal biology. Few might know, however, that alkaline phosphatase likely represents the most frequently assayed enzyme in all of medicine. Elevated activity in the circulation is universally recognized as a marker for skeletal or hepatobiliary disease. Alkaline Phosphatase (Germ type) /ALPG Protein, Rat, Recombinant (His) is expressed in HEK293... | |||
TMPY-02279 |
Nucleoside phosphorylase/PNP Protein, Human, Recombinant (His)
PUNP,PRO1837,purine nucleoside phosphorylase,NP |
Human | E. coli |
Purine nucleoside phosphorylase (PNP) is a purine-metabolizing enzyme that catalyzes the reversible phosphorolysis of 6-oxypurine (deoxy)nucleosides to their respective bases and (deoxy)ribose-1-phosphate. It is a key enzyme in the purine salvage pathway of mammalian cells. Purine nucleoside phosphorylase is a transferase that catalyzes the addition of phosphate and removal of a purine base from guanosine and similar nucleosides.PNP defects result in metabolic abnormalities and fatal T cell immu... | |||
TMPK-01150 |
Beta Klotho Protein, Mouse, Recombinant (His)
Klotho beta,β-klotho,MGC142213,βKlotho,β Klotho,KLB,beta-klo... |
Mouse | HEK293 Cells |
Beta-klotho (KLB) is a coreceptor required for endocrine fibroblast growth factor (FGF) 15/19 and FGF21 signaling in the brain. Klb is prominent within the hypothalamus, which is consistent with its metabolic functions, but diverse roles for Klb are now emerging. Central Klb expression is low but discrete and may govern FGF-targeted sites. Beta Klotho Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 109.91 kDa and the acce... | |||
TMPK-00347 |
Serum Albumin Protein, Human, Recombinant (His & Avi)
Serum albumin,PRO0903,Albumin,PRO1341,ALB,ANALBA,FDAH,PRO088... |
Human | HEK293 Cells |
Human serum albumin (HSA), the most prominent protein in plasma, binds different classes of ligands at multiple sites. HSA provides a depot for many compounds, affects pharmacokinetics of many drugs, holds some ligands in a strained orientation providing their metabolic modification, renders potential toxins harmless transporting them to disposal sites, accounts for most of the antioxidant capacity of human serum, and acts as a NO-carrier. Serum Albumin Protein, Human, Recombinant (His & Avi) is... | |||
TMPJ-00842 |
FGF-2 Protein, Rat, Recombinant
bFGF,Heparin-Binding Growth Factor 2,FGFB,Fibroblast Growth ... |
Rat | E. coli |
FGF-basic is a members of the Fibroblast Growth Factors (FGFs) family. The family constitutes a large family of proteins involved in many aspects of development including cell proliferation, growth, and differentiation. They act on several cell types to regulate diverse physiologic functions including angiogenesis, cell growth, pattern formation, embryonic development, metabolic regulation, cell migration, neurotrophic effects, and tissue repair. FGF-basic is a non-glycosylated heparin binding g... | |||
TMPY-01460 |
ABHD4 Protein, Human, Recombinant (His)
abhydrolase domain containing 4,ABH4 |
Human | Baculovirus Insect Cells |
Abhydrolase domain containing 4 (ABHD4), also known as alpha/beta-hydrolase 4 (ABH4) , or lyso-N-acylphosphatidylethanolamine lipase, which belongs to the ABHD4/ABHD5 subfamily of peptidase S33 family. Abhydrolase domain containing (ABHD) gene was a small group belongs to alpha/beta hydrolase superfamily. Known members of this group are all found to be involved in important biochemical processes and related to various diseases. The alpha/beta-hydrolase 4 (ABH4) is a lysophospholipase/phospholipa... | |||
TMPY-03962 |
AFM Protein, Human, Recombinant (His)
afamin,ALBA,ALB2,ALF |
Human | HEK293 Cells |
Afamin is an 87 kDa glycoprotein with five predicted N-glycosylation sites. Afamin's glycan abundance contributes to conformational and chemical inhomogeneity presenting great challenges for molecular structure determination. Afamin, a human plasma glycoprotein and putative transporter of hydrophobic molecules, has been shown to act as extracellular chaperone for poorly soluble, acylated Wnt proteins, forming a stable, soluble complex with functioning Wnt proteins. The 2.1-Å crystal structure of... | |||
TMPY-00566 |
CCL18 Protein, Human, Recombinant (His)
PARC,CCL18,CKb7,DC-CK1,chemokine (C-C motif) ligand 18,MIP-4... |
Human | P. pastoris (Yeast) |
CCL18 is a chemotactic cytokine involved in the pathogenesis and progression of various disorders, including cancer. Proof showed high levels of CCL18 in the serum of epithelial ovarian carcinoma patients suggesting its potential as a circulating biomarker. CCL18 chemokine has an important role in chemokine-mediated tumor metastasis, and may serve as a potential predictor for poor survival outcomes for ovarian cancer. (CCL18) is predominantly secreted by M2-tumor associated macrophages (TAMs) a... | |||
TMPH-00016 |
Ferredoxin Protein, Acetoanaerobium sticklandii, Recombinant (His & Myc)
Ferredoxin |
Acetoanaerobium sticklandii | E. coli |
Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. | |||
TMPH-00722 |
PykF Protein, E. coli, Recombinant (His)
Pyruvate kinase I,PK-1,pykF |
E. coli | E. coli |
Catalyzes the formation of pyruvate in the last step of glycolysis, it is irreversible under physiological conditions. The reaction is critical for the control of metabolic flux in the second part of glycolysis. | |||
TMPH-02988 |
UGPA Protein, Musa acuminata, Recombinant (His & Myc)
UGPA,UDP-glucose pyrophosphorylase,UTP--glucose-1-phosphate ... |
Musa acuminata | E. coli |
Plays a central role as a glucosyl donor in cellular metabolic pathways. UGPA Protein, Musa acuminata, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 58.8 kDa and the accession number is Q9SDX3. | |||
TMPH-03464 |
SUS1 Protein, S. cerevisiae, Recombinant (His & SUMO)
Sucrose-UDP glucosyltransferase,SUS1,Sucrose synthase |
Saccharum officinarum | E. coli |
Sucrose-cleaving enzyme that provides UDP-glucose and fructose for various metabolic pathways. SUS1 Protein, S. cerevisiae, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 41.3 kDa and the accession number is P31925. | |||
TMPY-04764 |
PCK2 Protein, Human, Recombinant (His & GST)
PEPCK-M,PEPCK2,PEPCK,phosphoenolpyruvate carboxykinase 2 (mi... |
Human | Baculovirus Insect Cells |
PCK2 promotes tumor initiation by lowering acetyl-CoA level through reducing the mitochondrial tricarboxylic acid (TCA) cycle. The levels of phosphoenolpyruvate carboxykinase isoform 2 (PCK2) are critical for the metabolic switch and the maintenance of TICs in prostate cancer. PCK2 is a potential therapeutic target for aggressive prostate tumors. | |||
TMPJ-01072 |
GALK2 Protein, Human, Recombinant (His)
GalNAc kinase,N-acetylgalactosamine kinase,Galactokinase 2,G... |
Human | HEK293 Cells |
GALK2 acts as a galactokinase when galactose is present at high concentrations. GALK2 may be involved in a salvage pathway for the reutilization of free GalNAc derived from the degradation of complex carbohydrates. GALK2 has been reported to participate in pathways , such as Amino sugar and nucleotide sugar metabolism, Galactose metabolism and Metabolic pathways. | |||
TMPY-04554 |
JNK1 Protein, Human, Recombinant (GST)
PRKM8,JNK,JNK-46,JNK21B1/2,JNK1A2,mitogen-activated protein ... |
Human | Baculovirus Insect Cells |
Mitogen-activated protein kinase 8 (MAPK8), also known as JNK1, is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation, and development. The protein kinases JNK1 has been found to serve as critical molecular links between obesity, metabolic inflammation, and disorders of glucose homeostasis. It is critically involved in ... | |||
TMPH-02509 |
ANGPTL8 Protein, Mouse, Recombinant (E. coli, His)
Angiopoietin-like protein 8,Lipasin,Gm6484,Refeeding-induced... |
Mouse | E. coli |
Hormone that acts as a blood lipid regulator by regulating serum triglyceride levels. May be involved in the metabolic transition between fasting and refeeding: required to direct fatty acids to adipose tissue for storage in the fed state. According to a report, may act by promoting ANGPTL3 cleavage. According to another study, not required for cleavage of ANGPTL3. | |||
TMPK-01274 |
DLK1 Protein, Cynomolgus, Recombinant (His)
FA1,DLK-1,secredeltin,DLK1,ZOG,DLK,Pref1,pG2 |
Cynomolgus | HEK293 Cells |
paternally inherited genetic defects of DLK1 were identified in four families with nonsyndromic CPP and a metabolic phenotype. DLK1 encodes a transmembrane protein that is important for adipose tissue homeostasis and neurogenesis and is located in the imprinted chromosome 14q32 region associated with Temple syndrome. DLK1 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 31.26 kDa and the accession number is A0A2K5TMQ6... | |||
TMPJ-00586 |
SULT1A2 Protein, Human, Recombinant (His)
STP2,Aryl Sulfotransferase 2,ST1A2,Phenol Sulfotransferase 2... |
Human | E. coli |
Sulfotransferase 1A2 (SULT1A2) is a member of the Sulfotransferase 1 family. Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. SULT1A2 is a cytoplasmic protein and exists as a homodimer. SULT1A2 mediates the metabolic activation of carcinogenic N-hydroxyarylamines to DNA binding products and might thus participate as a modulating factor of cancer risk. | |||
TMPH-02104 |
Sestrin-3/SESN3 Protein, Human, Recombinant (His & Myc)
Sestrin-3,SESN3 |
Human | E. coli |
May function as an intracellular leucine sensor that negatively regulates the TORC1 signaling pathway. May also regulate the insulin-receptor signaling pathway through activation of TORC2. This metabolic regulator may also play a role in protection against oxidative and genotoxic stresses. May prevent the accumulation of reactive oxygen species (ROS) through the alkylhydroperoxide reductase activity born by the N-terminal domain of the protein. | |||
TMPH-00735 |
LuxS Protein, E. coli, Recombinant (His & Myc)
luxS,S-ribosylhomocysteine lyase,Autoinducer-2 production pr... |
E. coli | E. coli |
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). | |||
TMPK-00922 |
DLK1 Protein, Human, Recombinant (aa 24-303, His)
FA1,Pref1,DLK1,pG2,DLK,secredeltin,ZOG,DLK-1 |
Human | HEK293 Cells |
paternally inherited genetic defects of DLK1 were identified in four families with nonsyndromic CPP and a metabolic phenotype. DLK1 encodes a transmembrane protein that is important for adipose tissue homeostasis and neurogenesis and is located in the imprinted chromosome 14q32 region associated with Temple syndrome. DLK1 Protein, Human, Recombinant (aa 24-303, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 30.9 kDa and the accession number is P8037... | |||
TMPK-00098 |
FGF-21 Protein, Human, Recombinant (mFc & Avi), Biotinylated
成纤维细胞生长因子,FGF-21,UNQ3115,FGF21,PRO10196 |
Human | HEK293 Cells |
Fibroblast growth factor 21 (FGF21) is a peptide hormone that is synthesized by several organs and regulates energy homeostasis. Excitement surrounding this relatively recently identified hormone is based on the documented metabolic beneficial effects of FGF21, which include weight loss and improved glycemia. FGF-21 Protein, Human, Recombinant (mFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with N-mFc-Avi tag. The predicted molecular weight is 46.9 kDa and the accession number i... | |||
TMPK-00097 |
FGF-21 Protein, Human, Recombinant (mFc & Avi)
FGF-21,PRO10196,FGF21,UNQ3115,成纤维细胞生长因子 |
Human | HEK293 Cells |
Fibroblast growth factor 21 (FGF21) is a peptide hormone that is synthesized by several organs and regulates energy homeostasis. Excitement surrounding this relatively recently identified hormone is based on the documented metabolic beneficial effects of FGF21, which include weight loss and improved glycemia. FGF-21 Protein, Human, Recombinant (mFc & Avi) is expressed in HEK293 mammalian cells with N-mFc-Avi tag. The predicted molecular weight is 46.9 kDa and the accession number is Q9NSA1-1. | |||
TMPJ-00989 |
MTHFS Protein, Human, Recombinant (His)
5-formyltetrahydrofolate cyclo-ligase,10-methenyl-tetrahydro... |
Human | E. coli |
5-formyltetrahydrofolate cyclo-ligase (MTHFS) belongs to the 5-formyltetrahydrofolate cyclo-ligase family. It is an enzyme that catalyzes the conversion of 5-formyltetrahydrofolate to 5,10-methenyltetrahydrofolate, contributes to tetrahydrofolate metabolism. MTHFS helps regulate carbon flow through the folate-dependent one-carbon metabolic network that supplies carbon for the biosynthesis of purines, thymidine and amino acids. An increased activity of the encoded protein can result in an increas... | |||
TMPY-02299 |
ALDH3A1 Protein, Human, Recombinant (His)
ALDHIII,aldehyde dehydrogenase 3 family, member A1,ALDH3 |
Human | Baculovirus Insect Cells |
Aldehyde dehydrogenase 3A1 (ALDH3A1) is a metabolic enzyme that catalyzes the oxidation of various aldehydes. Certain types of epithelial tissues in mammals, especially those continually exposed to environmental stress (e.g., corneal epithelium), express ALDH3A1 at high levels and its abundance in such tissues is perceived to help to maintain cellular homeostasis under conditions of oxidative stress. Metabolic as well as non-metabolic roles for ALDH3A1 have been associated with its mediated resi... | |||
TMPJ-00816 |
FBPase1 Protein, Human, Recombinant (His)
D-fructose-1,FBP,6-bisphosphate 1-phosphohydrolase 1,FBPase ... |
Human | HEK293 Cells |
Fructose-1,6-bisphosphatase 1(FBP1) is a homotetramer protein and belongs to the FBPase class 1 family. It involves in carbohydrate biosynthesis; gluconeogenesis pathway. FBP1 is a gluconeogenesis regulatory protein which catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate. FBP1 deficiency is associated with hypoglycemia and metabolic acidosis. FBP1 regulates mouse endogenous glucose production. FBP1 coupled with phosphofructokinase (PFK) takes p... | |||
TMPJ-00956 |
MDH2 Protein, Human, Recombinant (His)
MDH2,Malate dehydrogenase,mitochondrial |
Human | HEK293 Cells |
Malate dehydrogenase, mitochondrial is a 338 amino acids protein that belongs to the LDH/MDH superfamily. MDH type 1 family. MDH2 catalyzes the reversible oxidation of malate to oxaloacetate, utilizing the NAD/NADH cofactor system in the citric acid cycle. MDH2 is localized to the mitochondria and takes part in the malate-aspartate shuttle that functions in the metabolic coordination between cytosol and mitochondria. MDH2 is highly expressed in the adrenal system, small intestine, heart and panc... | |||
TMPK-00921 |
DLK1 Protein, Human, Recombinant (hFc)
DLK1,FA1,pG2,ZOG,secredeltin,DLK,Pref1,DLK-1 |
Human | HEK293 Cells |
paternally inherited genetic defects of DLK1 were identified in four families with nonsyndromic CPP and a metabolic phenotype. DLK1 encodes a transmembrane protein that is important for adipose tissue homeostasis and neurogenesis and is located in the imprinted chromosome 14q32 region associated with Temple syndrome. DLK1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 56.58 kDa and the accession number is P80370-1. | |||
TMPH-02510 |
ANGPTL8 Protein, Mouse, Recombinant (His)
Rifl,Refeeding-induced fat and liver protein,Betatrophin,Ang... |
Mouse | P. pastoris (Yeast) |
Hormone that acts as a blood lipid regulator by regulating serum triglyceride levels. May be involved in the metabolic transition between fasting and refeeding: required to direct fatty acids to adipose tissue for storage in the fed state. According to a report, may act by promoting ANGPTL3 cleavage. According to another study, not required for cleavage of ANGPTL3. ANGPTL8 Protein, Mouse, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 22.5 kDa and the... | |||
TMPK-00803 |
Alkaline Phosphatase (Germ type) /ALPG Protein, Human, Recombinant (His)
ALPG,ALPPL,Alkaline phosphatase, placental-like,Alkaline Pho... |
Human | HEK293 Cells |
Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal biology. Few might know, however, that alkaline phosphatase likely represents the most frequently assayed enzyme in all of medicine. Elevated activity in the circulation is universally recognized as a marker for skeletal or hepatobiliary disease. Alkaline Phosphatase (Germ type) /ALPG Protein, Human, Recombinant (His) is expressed in HEK2... | |||
TMPK-00796 |
Alkaline phosphatase (Intestinal type) /ALPI Protein, Human, Recombinant (His & Flag)
FLJ40094,ALPI,APTNAP,EC 3.1.3.1,AP-TNAP,IAP,TNAP,HOPS,FLJ930... |
Human | HEK293 Cells |
Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal biology. Few might know, however, that alkaline phosphatase likely represents the most frequently assayed enzyme in all of medicine. Elevated activity in the circulation is universally recognized as a marker for skeletal or hepatobiliary disease. Alkaline phosphatase (Intestinal type) /ALPI Protein, Human, Recombinant (His & Flag) is expr... | |||
TMPK-01326 |
Alkaline Phosphatase (Placental type) /ALPP Protein, Cynomolgus, Recombinant (His)
Alkaline phosphatase,PLAP,PLAP-1,ALPP |
Cynomolgus | HEK293 Cells |
Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal biology. Few might know, however, that alkaline phosphatase likely represents the most frequently assayed enzyme in all of medicine. Elevated activity in the circulation is universally recognized as a marker for skeletal or hepatobiliary disease. Alkaline Phosphatase (Placental type) /ALPP Protein, Cynomolgus, Recombinant (His) is express... | |||
TMPK-00801 |
Alkaline Phosphatase (Germ type) /ALPG Protein, Human, Recombinant (His & Avi), Biotinylated
ALPPL2,PLAP-like,GCAP,ALPG,Alkaline phosphatase, placental-l... |
Human | HEK293 Cells |
Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal biology. Few might know, however, that alkaline phosphatase likely represents the most frequently assayed enzyme in all of medicine. Elevated activity in the circulation is universally recognized as a marker for skeletal or hepatobiliary disease. Alkaline Phosphatase (Germ type) /ALPG Protein, Human, Recombinant (His & Avi), Biotinylated ... | |||
TMPK-00802 |
Alkaline Phosphatase (Germ type) /ALPG Protein, Human, Recombinant (hFc)
GCAP,ALPPL,Alkaline phosphatase, placental-like,Alkaline Pho... |
Human | HEK293 Cells |
Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal biology. Few might know, however, that alkaline phosphatase likely represents the most frequently assayed enzyme in all of medicine. Elevated activity in the circulation is universally recognized as a marker for skeletal or hepatobiliary disease. Alkaline Phosphatase (Germ type) /ALPG Protein, Human, Recombinant (hFc) is expressed in HEK2... | |||
TMPK-00804 |
Alkaline Phosphatase (Germ type) /ALPG Protein, Human, Recombinant (mFc)
GCAP,Alkaline Phosphatase,PLAP-like,Alkaline phosphatase, pl... |
Human | HEK293 Cells |
Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal biology. Few might know, however, that alkaline phosphatase likely represents the most frequently assayed enzyme in all of medicine. Elevated activity in the circulation is universally recognized as a marker for skeletal or hepatobiliary disease. Alkaline Phosphatase (Germ type) /ALPG Protein, Human, Recombinant (mFc) is expressed in HEK2... | |||
TMPH-00734 |
LuxS Protein, E. coli, Recombinant (His)
AI-2 synthesis protein,Autoinducer-2 production protein LuxS... |
E. coli | E. coli |
Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). LuxS Protein, E. coli, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. Th... | |||
TMPK-00684 |
Alkaline phosphatase (Intestinal type) /ALPI Protein, Mouse, Recombinant (His)
IAP,TNSALP,APTNAP,FLJ40094,AP-TNAP,MGC161443,TNAP,Akp2,HOPS,... |
Mouse | HEK293 Cells |
Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal biology. Few might know, however, that alkaline phosphatase likely represents the most frequently assayed enzyme in all of medicine. Elevated activity in the circulation is universally recognized as a marker for skeletal or hepatobiliary disease. Alkaline phosphatase (Intestinal type) /ALPI Protein, Mouse, Recombinant (His) is expressed i... | |||
TMPK-00855 |
Alkaline Phosphatase (Germ type) /ALPG Protein, Mouse, Recombinant (His)
Alkaline Phosphatase,Alppl2,Akp5,Alpg,Alkaline phosphatase, ... |
Mouse | HEK293 Cells |
Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal biology. Few might know, however, that alkaline phosphatase likely represents the most frequently assayed enzyme in all of medicine. Elevated activity in the circulation is universally recognized as a marker for skeletal or hepatobiliary disease. Alkaline Phosphatase (Germ type) /ALPG Protein, Mouse, Recombinant (His) is expressed in HEK2... | |||
TMPK-01078 |
Beta Klotho Protein, Human, Recombinant (His)
beta-klotho,MGC142213,betaKlotho,BKL,β-klotho,KLB,klotho bet... |
Human | HEK293 Cells |
Beta-klotho (KLB) is a coreceptor required for endocrine fibroblast growth factor (FGF) 15/19 and FGF21 signaling in the brain. Klb is prominent within the hypothalamus, which is consistent with its metabolic functions, but diverse roles for Klb are now emerging. Central Klb expression is low but discrete and may govern FGF-targeted sites. Beta Klotho Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 111.6 kDa and the acces... | |||
TMPH-02527 |
ASS1 Protein, Mouse, Recombinant (His & Myc)
Ass,Citrulline--aspartate ligase,Ass1,Argininosuccinate synt... |
Mouse | E. coli |
One of the enzymes of the urea cycle, the metabolic pathway transforming neurotoxic amonia produced by protein catabolism into inocuous urea in the liver of ureotelic animals. Catalyzes the formation of arginosuccinate from aspartate, citrulline and ATP and together with ASL it is responsible for the biosynthesis of arginine in most body tissues. ASS1 Protein, Mouse, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 5... | |||
TMPK-00150 |
FOLR1 Protein, Human, Recombinant (His & Avi)
Folate receptor 1,Folbp1,Folate receptor alpha,FR-alpha,FR a... |
Human | HEK293 Cells |
Folate Receptor 1 (FOLR1), also known as Folate Receptor alpha and Folate Binding Protein (FBP), is a 37 - 42 kDa protein that mediates the cellular uptake of folic acid and reduced folates. Dietary folates are required for many key metabolic processes including nucleotide and methionine synthesis, the interconversion of glycine and serine, and histidine breakdown. FOLR1 binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into t... | |||
TMPK-01319 |
GFRAL/GFR alpha-like Protein, Cynomolgus, Recombinant (His & Avi)
GFR alpha like,GRAL,GFRAL,C6orf144,GFRAL/GFR α-like Protein,... |
Cynomolgus | HEK293 Cells |
GFR alpha -like (GDNF receptor-alpha-like) is a distant member of the GDNFR family of proteins. Mature human GFR alpha-like is a 376 amino acid (aa) type I transmembrane protein. It contains a 333 aa extracellular domain, a 20 aa transmembrane domain and a 23 aa cytoplasmic domain.GFRAL is a brainstem-restricted receptor for GDF15 which regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses. GFRAL/GFR alpha-like Protein, Cynomolgus, Recombin... | |||
TMPK-01053 |
GFRAL/GFR alpha-like Protein, Mouse, Recombinant (His & Avi), Biotinylated
GRAL,GFRAL/GFR α-like Protein,GFR alpha-like,GFR α-like,GFRA... |
Mouse | HEK293 Cells |
GFR alpha -like (GDNF receptor-alpha-like) is a distant member of the GDNFR family of proteins. Mature human GFR alpha-like is a 376 amino acid (aa) type I transmembrane protein. It contains a 333 aa extracellular domain, a 20 aa transmembrane domain and a 23 aa cytoplasmic domain.GFRAL is a brainstem-restricted receptor for GDF15 which regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses. GFRAL/GFR alpha-like Protein, Mouse, Recombinant (... | |||
TMPK-00348 |
Serum Albumin Protein, Human, Recombinant (His & Avi), Biotinylated
ALB,PRO0883,PRO0903,FDAH,ANALBA,PRO1341,Serum albumin,Albumi... |
Human | HEK293 Cells |
Human serum albumin (HSA), the most prominent protein in plasma, binds different classes of ligands at multiple sites. HSA provides a depot for many compounds, affects pharmacokinetics of many drugs, holds some ligands in a strained orientation providing their metabolic modification, renders potential toxins harmless transporting them to disposal sites, accounts for most of the antioxidant capacity of human serum, and acts as a NO-carrier. Serum Albumin Protein, Human, Recombinant (His & Avi), B... | |||
TMPK-01320 |
GFRAL/GFR alpha-like Protein, Cynomolgus, Recombinant (His & Avi), Biotinylated
GRAL,GFRAL,C6orf144,GFRAL/GFR α-like Protein,GFR α-like,GFR ... |
Cynomolgus | HEK293 Cells |
GFR alpha -like (GDNF receptor-alpha-like) is a distant member of the GDNFR family of proteins. Mature human GFR alpha-like is a 376 amino acid (aa) type I transmembrane protein. It contains a 333 aa extracellular domain, a 20 aa transmembrane domain and a 23 aa cytoplasmic domain.GFRAL is a brainstem-restricted receptor for GDF15 which regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses. GFRAL/GFR alpha-like Protein, Cynomolgus, Recombin... | |||
TMPK-01052 |
GFRAL/GFR alpha-like Protein, Mouse, Recombinant (His & Avi)
GFRAL/GFR α-like Protein,GFR α-like,GRAL,C6orf144,GFR alpha-... |
Mouse | HEK293 Cells |
GFR alpha -like (GDNF receptor-alpha-like) is a distant member of the GDNFR family of proteins. Mature human GFR alpha-like is a 376 amino acid (aa) type I transmembrane protein. It contains a 333 aa extracellular domain, a 20 aa transmembrane domain and a 23 aa cytoplasmic domain.GFRAL is a brainstem-restricted receptor for GDF15 which regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses. GFRAL/GFR alpha-like Protein, Mouse, Recombinant (... | |||
TMPY-03055 |
LYG1 Protein, Human, Recombinant (His)
SALW1939,lysozyme G-like 1 |
Human | Baculovirus Insect Cells |
LYG1 (Lysozyme G1) is a Protein Coding gene. It belongs to the glycosyl hydrolase 23 family. Glycoside hydrolases are a widespread group of enzymes that hydrolyze the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. LYG1 exhibits hydrolase activity, acting on glycosyl bonds (inferred); lysozyme activity (inferred). It is found in the extracellular region and may function in the cell wall macromolecule catabolic process, metabolic process... | |||
TMPY-03446 |
ENO3 Protein, Human, Recombinant (His)
enolase 3 (beta, muscle),GSD13,MSE,enolase 3 (β, muscle) |
Human | E. coli |
ENO3 is one of the three enolase isoenzymes found in mammals. As a homodimer, ENO3 is found in skeletal muscle cells in the adult. A switch from alpha enolase to beta enolase occurs in muscle tissue during development in rodents. Mutations in ENO3 gene can be associated with metabolic myopathies that may result from decreased stability of the enzyme. Two transcripts have been identified for ENO3 gene that differ only in their 5' UTR. ENO3 may play a role in muscle development and regenera... | |||
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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T19261 |
D-Glucose-13C6
D-(+)-Glucose-13C6,Glucose-13C6,Dextrose-13C6 |
Endogenous Metabolite | Metabolism |
D-Glucose-13C6 (Dextrose-13C6) 是一种 D-Glucose 的同位素标记物,可作为代谢示踪剂,可用于研究机体代谢相关疾病和部分物质的代谢过程。 | |||
TMID-0064 |
Androsterone-d4
|
||
Androsterone-d4 是 Androsterone 的氘代化合物。Androsterone 的 CAS 号为 53-41-8。Androsterone 是睾酮的代谢产物,可以激活法尼醇 X 受体。 | |||
TMIH-0335 |
Methotrexate-d3
|
ADC Cytotoxin | Antibody-drug Conjugate/ADC Related |
Methotrexate-d3 是 Methotrexate 的氘代化合物。Methotrexate 的 CAS 号为 59-05-2。Methotrexate 是一种叶酸类似物代谢抑制剂,具有免疫抑制剂和抗肿瘤特性,用于类风湿关节炎和研究多种癌症。 | |||
T35790 |
Palmitic acid-1,2,3,4-13C4
Palmitic Acid-13C (C1, C2, C3, and C4 labeled) |
||
Palmitic acid-13C (C1, C2, C3, and C4 labeled) is intended for use as an internal standard for the quantification of palmitic acid by GC- or LC-MS. Palmitic acid is a common 16-carbon saturated fat that represents 10-20% of human dietary fat intake and comprises approximately 25 and 65% of human total plasma lipids and saturated fatty acids, respectively.1,2Acylation of palmitic acid to proteins facilitates anchoring of membrane-bound proteins to the lipid bilayer and trafficking of intracellula... | |||
TMIH-0241 |
Fluphenazine-d8 Dihydrochloride
|
||
Fluphenazine-d8 Dihydrochloride 是 Fluphenazine Dihydrochloride 的氘代化合物。Fluphenazine Dihydrochloride 的 CAS 号为 146-56-5。Fluphenazine hydrochloride 是一种多巴胺受体D1/D2抑制剂。 | |||
TMIJ-0139 |
Ticagrelor-d7
|
||
Ticagrelor-d7 是 Ticagrelor 的氘代化合物。Ticagrelor 的 CAS 号为 274693-27-5。Ticagrelor (AZD6140) 是可逆的,可口服的P2Y12受体拮抗剂,可抑制血小板聚集。 | |||
TMIH-0181 |
Demethoxy Curcumin-d4
|
||
Demethoxy Curcumin-d4 是 Demethoxy Curcumin 的氘代化合物。Demethoxy Curcumin 的 CAS 号为 22608-11-3。Demethoxycurcumin是姜黄素的主要活性成分,有抗炎和抗癌作用。 | |||
TMIJ-0204 |
Betamethasone-d10 Dipropionate
|
||
Betamethasone-d10 Dipropionate 是 Betamethasone Dipropionate 的氘代化合物。Betamethasone Dipropionate 的 CAS 号为 5593-20-4。Betamethasone dipropionate 是糖皮质激素类固醇,具有免疫抑制、抗炎作用。 | |||
TMIJ-0374 |
L-Leucine-d3
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L-Leucine-d3 是 L-Leucine 的氘代化合物。L-Leucine 的 CAS 号为 61-90-5。L-Leucine 是必需的支链氨基酸,能够激活mTOR信号通路。 | |||
TMIJ-0081 |
L-Leucine-d10
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L-Leucine-d10 是 L-Leucine 的氘代化合物。L-Leucine 的 CAS 号为 61-90-5。L-Leucine 是必需的支链氨基酸,能够激活mTOR信号通路。 | |||
TMID-0303 |
Vitamin A-d4
Retinol-d4 |
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Vitamin A-d4 是 Vitamin A 的氘代化合物。Vitamin A 的 CAS 号为 68-26-8。Retinol 及其衍生物,在视网膜的代谢功能、上皮组织的生长和分化、骨骼的生长、生殖和免疫反应中起重要作用。膳食维生素 A 来源于植物中发现的多种类胡萝卜素。它富含肝脏、蛋黄和乳制品的脂肪成分。 | |||
T69395 |
Nicotinamide-d4
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Nicotinamide-d4 is intended for use as an internal standard for the quantification of nicotinamide by GC- or LC-MS. Nicotinamide is an amide form of niacin, which is also known as vitamin B3, that can be biosynthesized in vivo or obtained through the diet. It is a precursor in the synthesis of the metabolic cofactor NAD+ and an inhibitor of sirtuin 1 (SIRT1; IC50 = <50 µM). Nicotinamide (10 µM) increases the activity of serine palmitoyltransferase (SPT) and the biosynthesis of ceramide, glucosyl... | |||
TMIJ-0384 |
L-Cysteine-d3
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L-Cysteine-d3 是 L-Cysteine 的氘代化合物。L-Cysteine 的 CAS 号为 52-90-4。L-Cysteine 是人体非必需的含硫氨基酸。L-Cysteine 对蛋白质合成、解毒和多种代谢功能很重要。L-Cysteine 存在于指甲、皮肤和头发的主要蛋白质-角蛋白中,对胶原蛋白的生成、皮肤弹性和质地都很重要。L-Cysteine 是抗氧化剂谷胱甘肽的一种成分,在辅酶A、肝素和生物素等基本生化物质的代谢中起着重要作用,也是氨基酸牛磺酸的制造所必需的。 | |||
TMIJ-0054 |
Propionic-2,2-d2 acid
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Propionic-2,2-d2 acid 是 Propionic acid 的氘代化合物。Propionic acid 的 CAS 号为 79-09-4。Propionic acid 被广泛用作食品中的抗真菌剂。它以低水平天然存在于乳制品中,并与其他短链脂肪酸 (SCFA) 一起普遍存在于人类和其他哺乳动物的胃肠道中,作为微生物消化碳水化合物的最终产物。在动物体内有显着的生理活性。 | |||
TMIJ-0052 |
Propionicacid-d5
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Propionicacid-d5 是 Propionicacid 的氘代化合物。Propionicacid 的 CAS 号为 79-09-4。Propionic acid 被广泛用作食品中的抗真菌剂。它以低水平天然存在于乳制品中,并与其他短链脂肪酸 (SCFA) 一起普遍存在于人类和其他哺乳动物的胃肠道中,作为微生物消化碳水化合物的最终产物。在动物体内有显着的生理活性。 |