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Search Results for " oxidase "
Targets Recommended: NADPH-oxidase Glutathione Peroxidase stilbene oxidase Xanthine Oxidase Monoamine Oxidase Xanthine Oxidase

342

抑制剂 & 化合物

88

天然产物

1

化合物库

77

重组蛋白

16

同位素标记化合物

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Cat. No. Product Name
L9830 抗帕金森病化合物库

857 compounds
857 种帕金森病相关的化合物集合,可用于高通量和高内涵筛选;

化合物库

抗帕金森病化合物库
Cat.No: L9830
Compounds: 857
Cat. No. Product Name Target Signaling Pathways
T10509 Xanthine oxidase-IN-1

4-(3-Cyano-5,6-difluoroindol-1-yl)-2-hydroxybenzoic acid

Xanthine Oxidase Metabolism
Xanthine oxidase-IN-1是一种有效的黄嘌呤氧化酶抑制剂(IC50值:6.5 nM),是一种利用核酸和核苷酸介质降解产生的生物活性核苷酸在嘌呤分解代谢中起核心作用的化合物,
T76148 Glucose oxidase

Endogenous Metabolite Metabolism
Glucose oxidase 是从真菌黑曲霉中提取的酶,是食品工业中一种重要的工业用酶, 广泛用于葡萄酒、啤酒、果汁、奶粉等食品脱氧、面粉改良、防止食品褐变等方面。Glucose oxidase 具有抗氧化和潜在的抗癌活性。
T78984 Xanthine oxidase-IN-10

XO8 analog

ROS Immunology/Inflammation
Xanthine oxidase-IN-10 (XO8 analog) 是一种黄嘌呤氧化酶 (XO) 抑制剂,可用于研究痛风。
T76104 Xanthine oxidase

黄嘌呤氧化酶

Others Others
Xanthine oxidase 是一种黄嘌呤氧化还原酶,可产生活性氧 (ROS),催化次黄嘌呤氧化为黄嘌呤,进一步催化黄嘌呤氧化为尿酸。
T11429 Glycolic acid oxidase inhibitor 1

Others Others
Glycolic acid oxidase inhibitor 1 is a glycolate oxidase inhibitor.
T78358 Choline oxidase

Others Others
Choline oxidase 通过催化胆碱氧化成甜菜碱醛,在甘氨酸甜菜碱生物合成中扮演关键角色,汲取其作为渗透剂的功能。此酶在促进甜菜碱生产方面展现出潜力。
T75422 Monoamine oxidase

Others Others
Monoamine oxidase 是一种由不同多肽组成的酶。Monoamine oxidase 通过产生过氧化氢催化大脑和外周组织中多种生物胺氧化脱氨。Monoamine oxidase 在维持突触神经传递、情绪行为和其他大脑功能的调节中发挥重要作用。
T76101 Ascorbate oxidase

Others Others
Ascorbate oxidase(即维生素 C 氧化酶),作为一种氧化还原酶,在细胞外基质中的氧化还原调节中起作用。该酶催化抗坏血酸与氧之间的反应,生成脱氢抗坏血酸。
T76143 Pyruvate oxidase

Others Others
Pyruvate oxidase(PoxB) 是一种焦磷酸硫胺素依赖型的氧化酶,可以催化丙酮酸氧化脱羧生成乙酰磷酸、二氧化碳和水。Pyruvate oxidase 是细菌代谢中的一种重要酶,常用于生化研究。
T73617 Urate oxidase

Others Others
Urate oxidase (Uox) 尿酸氧化酶,即尿酸酶,常用于生化研究。Urate oxidase 是一种过氧化物酶,在大多数哺乳动物中催化尿酸氧化为尿囊素。
T78348 Lactate oxidase

Others Others
Lactate oxidase是一种FMN依赖性酶,能催化乳酸转化为丙酮酸并同时释放过氧化氢,常用于乳酸的检测。
T76131 Sarcosine oxidase

Others Others
Sarcosine oxidase(SAO),即肌氨酸氧化酶,可以催化肌氨酸的氧化去甲基化生成甘氨酸,H2O2, 5,10-CH2-四氢叶酸,常用于生化反应。
T76128 Cholesterol oxidase

Others Others
Cholesteroloxidase (ChOx),一种含有FAD的细菌黄素氧化酶,主要应用于生化研究领域。该酶专门催化胆固醇(及其他甾醇)的C(3)-OH基团,氧化生成cholest-5-en-3-one,并进一步异构化为cholest-4-en-3-one。
T76105 Alcohol oxidase

Others Others
Alcohol oxidase 是甲醇利用途径的功能酶,能够从酵母的过氧化物酶体中分离得到。
T76141 Bilirubin oxidase

Others Others
Bilirubin oxidase (BOD) 为一多铜氧化酶,能催化胆红素氧化为胆绿素,同时将分子氧还原成水。该酶在卟啉及叶绿素代谢中起作用,并作为氧还原催化剂在生化研究中广泛应用。
T76150 Galactose oxidase

Others Others
Galactose oxidase (GOase) 半乳糖氧化酶来自真菌,常用于生化研究。Galactose oxidase 是一种 II 型铜金属酶,含有单一多肽。Galactose oxidase 催化伯醇的双电子氧化生成相应的醛,并将二氧还原为过氧化氢。
T60626 Xanthine oxidase-IN-7

Others Others
Xanthine oxidase-IN-7 (compound1h) 是一种口服的黄嘌呤氧化酶(XO)抑制剂 (IC50 = 0.36 μM)。Xanthine oxidase-IN-7 可有效降低血清尿酸水平,在高尿酸血症和痛风的研究中具有潜力。
T61092 Xanthine oxidase-IN-5

Others Others
Xanthine oxidase-IN-5, a powerful and orally active inhibitor of xanthine oxidase (XO), exhibits an IC50 value of 0.70 μM. It possesses favorable drug-like characteristics, with ligand efficiency (LE) and lipophilic ligand efficiency (LLE) values of 0.33 and 3.41, respectively. Moreover, Xanthine oxidase-IN-5 showcases significant hypouricemic effects in a hyperuricemic rat model [1].
T80767 Xanthine oxidase-IN-12

Xanthine Oxidase Metabolism
Xanthine oxidase-IN-12 (Compound 11), 作为一种高效的黄嘌呤氧化酶 (XO) 抑制剂,其IC50值达到91 nM。此外,Xanthine oxidase-IN-12 亦展现出抗氧化活性,能降低细胞内活性氧种 (ROS) 的水平。
T76170 D-Amino acid oxidase

Others Others
D-Amino acid oxidase 是一种酶,主要负责在动物体内代谢外源性 D-氨基酸以进行解毒,并能够调节大脑中D-丝氨酸的水平。
T78356 Fructosyl amino acid oxidase

Others Others
Fructosyl amino acid oxidase是测量糖化蛋白的重要试剂,特别是用于评估糖尿病指标糖化血红蛋白A1c。
T72409 Xanthine oxidase-IN-6

Others Others
Xanthine oxidase-IN-6 是一种强效的、具有口服活性的黄嘌呤氧化酶 (XOD) 混合型抑制剂,其IC50值为1.37 µM。Xanthine oxidase-IN-6 具有很强的抗高尿酸血症 (anti-hyperuricemia) 和肾保护活性。
T76171 L-Amino acid oxidase

Others Others
L-Amino acid oxidase(L-氨基酸氧化酶)是一种含黄素腺嘌呤二核苷酸的同源二聚体,能够将L-氨基酸立体特异性地催化氧化脱氨,生成α-酮酸和氨。
T78985 Xanthine oxidase-IN-11

Xanthine Oxidase Metabolism
Xanthine oxidase-IN-11 (XO8 analog) 是一种有效的黄嘌呤氧化酶 (XO) 抑制剂。
T60632 Xanthine oxidase-IN-4

Others Others
Xanthine oxidase-IN-4 (化合物 19a) 是一种具有口服活性的有效黄嘌呤氧化酶 (XO) 抑制剂,IC50值为0.039 μM,可用于高尿酸血症和痛风的研究。Xanthine oxidase-IN-4 在氧嗪酸钾诱导的高尿酸血症大鼠中表现出降尿酸能力。
T82289 Glycolate oxidase-IN-1

Others Others
Glycolate oxidase-IN-1(化合物26),一种水杨酸衍生物,作为乙醇酸氧化酶 (GO) 抑制剂,展现出38.2 μM的IC50。该化合物能有效降低原发性高草酸尿症 1 型 (PH1) 患者肝细胞中的草酸盐生成,有助于相关疾病的研究。
T8849 PF-9601N

MAO Metabolism; Neuroscience
PF-9601N 是一种单胺氧化酶 B (MAO-B) 抑制剂,在多种体内外模型中表现出抗帕金森病 (PD) 的神经保护作用。它可用于研究兴奋性毒性介导的神经退行性疾病。
T76098 Glycerol-3-phosphate oxidase

Others Others
Glycerol-3-phosphate oxidase,即磷酸甘油氧化酶,是甘油代谢的关键中间体。Glycerol-3-phosphate oxidase 能够从大肠杆菌中提取得到。Glycerol-3-phosphate oxidase 是膜脂质的磷脂的骨架,也是呼吸链的底物。Glycerol-3-phosphate oxidase 通过氧化产生电子。
T60656 Monoamine Oxidase B inhibitor 1

Others Others
Monoamine Oxidase B inhibitor 1 是一种可逆、口服有效和选择性的单胺氧化酶 B 抑制剂 (IC50 = 0.02 nM),可以穿过血脑屏障 (BBB)。Monoamine Oxidase B inhibitor 1 显示出抗氧化和抗神经炎症活性,可用于研究帕金森病。
T60806 Monoamine Oxidase B inhibitor 2

Others Others
Monoamine Oxidase B inhibitor 2 是有可逆并且口服有效的和选择性的单胺氧化酶 B (MAO-B) 抑制剂(IC50 = 1.33 nM) ,可以透过血脑屏障 (BBB)。Monoamine Oxidase B inhibitor 2 显示出抗氧化和抗神经炎症活性,可用于研究帕金森病。
T39280 Nitrofen

Others Others
Nitrofen 是选择性接触除草剂,也是视原卟啉原氧化酶和网膜脱氢酶抑制剂。
T4559 Isocarboxazid

Monoamine Oxidase Neuroscience
Isocarboxazid 是不可逆的、非选择性的单胺氧化酶 monoamine oxidase 抑制剂,其在大鼠大脑中测得的 IC50值为4.8 μM。
T61463 Monoamine oxidase/Aromatase-IN-1

Others Others
Monoamine oxidase/Aromatase-IN-1 (compound 2q) is a potent dual inhibitor of monoamine oxidase (MAO) and aromatase, with IC50 values of 39 nM and 31 nM for MAO-B and aromatase, respectively. It holds significant potential for research in neurological disorders and breast cancer [1].
T0235 Modaline sulfate

MAO; Monoamine Oxidase Metabolism; Neuroscience
Modaline sulfate 是一种 MAO 抑制剂,用于研究抑郁症。
T22605 Bifemelane hydrochloride

MAO; Monoamine Oxidase Metabolism; Neuroscience
Bifemelane hydrochloride 是一种选择性的,有效的,和竞争性的单胺氧化酶A (MAO-A)抑制剂,Ki=4.20 μM,它也非竞争性地抑制MAO-B,Ki=46.0 μM。它具有显著的抗抑郁作用,可用于研究与脑血管疾病有关的认知和情绪障碍。
T39986 LOX-IN-3 dihydrochloride

Lipoxygenase Metabolism
LOX-IN-3 dihydrochloride 是口服有效的赖氨酰氧化酶抑制剂,在纤维化,癌症和/或血管生成方面有研究价值。
T72299 Mtb-cyt-bd oxidase-IN-3

Others Others
Mtb-cyt-bd oxidase-IN-3 是一种结核分枝杆菌细胞色素氧化酶 (Mtb cyt-bd oxidase) 抑制剂,IC50值为 0.36 μM。Mtb-cyt-bd oxidase-IN-3 能有效抑制Mycobacterium tuberculosis 的生长 (MIC=32 μM),其可用于结核病的研究。
T72300 Mtb-cyt-bd oxidase-IN-4

Others Others
Mtb-cyt-bd oxidase-IN-4 是一种结核分枝杆菌细胞色素氧化酶 (Mtb cyt-bd oxidase) 抑制剂,IC50值为 0.25 μM。Mtb-cyt-bd oxidase-IN-4 能有效抑制Mycobacterium tuberculosis 的生长 (MIC=8 μM),其可用于结核病的研究。
T72297 Mtb-cyt-bd oxidase-IN-1

Others Others
Mtb-cyt-bd oxidase-IN-1 是一种结核分枝杆菌细胞色素氧化酶 (Mtb cyt-bd oxidase) 抑制剂,IC50值为 0.13 μM,其可用于结核病的研究。
T72305 Mtb-cyt-bd oxidase-IN-7

Others Others
Mtb-cyt-bd oxidase-IN-7 是一种细胞色素 bd 末端氧化酶 (Cyt-bd) 抑制剂,Kd 值为 4.17 μM。Mtb-cyt-bd oxidase-IN-7 具有抗结核活性。
T72302 Mtb-cyt-bd oxidase-IN-6

Others Others
Mtb-cyt-bd oxidase-IN-6为结核分枝杆菌细胞色素bd氧化酶(cyt-bd)的抑制剂,具有0.35 μM的IC50值,并且在MIC为4 μM时能有效抑制Mtb生长,适用于结核病研究领域。
T0084 Moclobemide

吗氯贝胺,Ro111163

MAO; Monoamine Oxidase Metabolism; Neuroscience
Moclobemide (Ro111163) 是可逆的、可透过血脑屏障的单胺氧化酶 (MAO-A) 抑制剂,能够抑制 hMAO-A (IC50=6.061 μM)。它上调慢性应激小鼠海马祖细胞的增殖。
T12584 PXS-5120A

Others; Monoamine Oxidase Neuroscience; Others
PXS-5120A 是一种不可逆的 Lysyl Oxidase-like 2/3 (LOXL2/3) 的氟代烯丙胺抑制剂,具有抗纤维化活性。
T12585 PXS-5153A

Others; Monoamine Oxidase Neuroscience; Others
PXS-5153A 是一种有效、特异性和速效的Lysyl Oxidase-like 2/3 (LOXL2/3) 抑制剂,其酶活性在 15 分钟内几乎完全阻断。 PXS-5153A 可以减少交联并改善纤维化。
T4359 VAS2870

NADPH Metabolism
VAS2870 是一种NADPH 氧化酶抑制剂。
T16803 RS 8359

MAO Metabolism; Neuroscience
RS 8359 是单胺氧化酶 A (MAO-A) 的可逆抑制剂,对 A:B 酶类型的特异性比约为 2200。 RS 8359 具有抗抑郁活性。
T7626 Budipine

Others Others
Budipine 是抗帕金森病剂的一种。
T1993 J-147

J147

Epigenetic Reader Domain; Dopamine Receptor; Monoamine Oxidase Chromatin/Epigenetic; GPCR/G Protein; Neuroscience
J-147 是一种高效的、具有口服活性的、可透过血脑屏障神经保护剂,可增强认知能力。它抑制单胺氧化酶 B 和多巴胺转运体,EC50分别为 1.88 μM 和 0.649 μM。它有研究阿尔茨海默氏症的潜力。
T8408 GKT136901

AK120765

NADPH-oxidase; NADPH Immunology/Inflammation; Metabolism
GKT136901 (AK120765) 是选择性的和具有口服活性的 NADPH 氧化酶 NOX-1/4抑制剂,Ki 分别为 160 和 165 nM。它具有抗炎症活性。它也是一种选择性和直接的过氧亚硝酸清除剂。它可用于糖尿病肾病,中风和神经退行性疾病的研究。
T8107 GLX351322

NADPH-oxidase; NADPH Immunology/Inflammation; Metabolism
GLX351322 抑制 NADPH 氧化酶 4 (Nox4) 。在 NOX4 过表达的细胞中,抑制过氧化氢的产生,IC50值为 5 μM。

化合物

Xanthine oxidase-IN-1
Cat.No: T10509
Synonym: 4-(3-Cyano-5,6-difluoroindol-1-yl)-2-hydroxybenzoic acid
Target: Xanthine Oxidase
Glucose oxidase
Cat.No: T76148
Synonym:
Target: Endogenous Metabolite
Xanthine oxidase-IN-10
Cat.No: T78984
Synonym: XO8 analog
Target: ROS
Xanthine oxidase
Cat.No: T76104
Synonym: 黄嘌呤氧化酶
Target: Others
Glycolic acid oxidase inhibitor 1
Cat.No: T11429
Synonym:
Target: Others
Choline oxidase
Cat.No: T78358
Synonym:
Target: Others
Monoamine oxidase
Cat.No: T75422
Synonym:
Target: Others
Ascorbate oxidase
Cat.No: T76101
Synonym:
Target: Others
Pyruvate oxidase
Cat.No: T76143
Synonym:
Target: Others
Urate oxidase
Cat.No: T73617
Synonym:
Target: Others
Lactate oxidase
Cat.No: T78348
Synonym:
Target: Others
Sarcosine oxidase
Cat.No: T76131
Synonym:
Target: Others
Cholesterol oxidase
Cat.No: T76128
Synonym:
Target: Others
Alcohol oxidase
Cat.No: T76105
Synonym:
Target: Others
Bilirubin oxidase
Cat.No: T76141
Synonym:
Target: Others
Galactose oxidase
Cat.No: T76150
Synonym:
Target: Others
Xanthine oxidase-IN-7
Cat.No: T60626
Synonym:
Target: Others
Xanthine oxidase-IN-5
Cat.No: T61092
Synonym:
Target: Others
Xanthine oxidase-IN-12
Cat.No: T80767
Synonym:
Target: Xanthine Oxidase
D-Amino acid oxidase
Cat.No: T76170
Synonym:
Target: Others
Fructosyl amino acid oxidase
Cat.No: T78356
Synonym:
Target: Others
Xanthine oxidase-IN-6
Cat.No: T72409
Synonym:
Target: Others
L-Amino acid oxidase
Cat.No: T76171
Synonym:
Target: Others
Xanthine oxidase-IN-11
Cat.No: T78985
Synonym:
Target: Xanthine Oxidase
Xanthine oxidase-IN-4
Cat.No: T60632
Synonym:
Target: Others
Glycolate oxidase-IN-1
Cat.No: T82289
Synonym:
Target: Others
PF-9601N
Cat.No: T8849
Synonym:
Target: MAO
Glycerol-3-phosphate oxidase
Cat.No: T76098
Synonym:
Target: Others
Monoamine Oxidase B inhibitor 1
Cat.No: T60656
Synonym:
Target: Others
Monoamine Oxidase B inhibitor 2
Cat.No: T60806
Synonym:
Target: Others
Nitrofen
Cat.No: T39280
Synonym:
Target: Others
Isocarboxazid
Cat.No: T4559
Synonym:
Target: Monoamine Oxidase
Monoamine oxidase/Aromatase-IN-1
Cat.No: T61463
Synonym:
Target: Others
Modaline sulfate
Cat.No: T0235
Synonym:
Target: MAO, Monoamine Oxidase
Bifemelane hydrochloride
Cat.No: T22605
Synonym:
Target: MAO, Monoamine Oxidase
LOX-IN-3 dihydrochloride
Cat.No: T39986
Synonym:
Target: Lipoxygenase
Mtb-cyt-bd oxidase-IN-3
Cat.No: T72299
Synonym:
Target: Others
Mtb-cyt-bd oxidase-IN-4
Cat.No: T72300
Synonym:
Target: Others
Mtb-cyt-bd oxidase-IN-1
Cat.No: T72297
Synonym:
Target: Others
Mtb-cyt-bd oxidase-IN-7
Cat.No: T72305
Synonym:
Target: Others
Mtb-cyt-bd oxidase-IN-6
Cat.No: T72302
Synonym:
Target: Others
Moclobemide
Cat.No: T0084
Synonym: 吗氯贝胺,Ro111163
Target: MAO, Monoamine Oxidase
PXS-5120A
Cat.No: T12584
Synonym:
Target: Others, Monoamine Oxidase
PXS-5153A
Cat.No: T12585
Synonym:
Target: Others, Monoamine Oxidase
VAS2870
Cat.No: T4359
Synonym:
Target: NADPH
RS 8359
Cat.No: T16803
Synonym:
Target: MAO
Budipine
Cat.No: T7626
Synonym:
Target: Others
J-147
Cat.No: T1993
Synonym: J147
Target: Epigenetic Reader Domain, Dopamine Receptor, Monoamine Oxidase
GKT136901
Cat.No: T8408
Synonym: AK120765
Target: NADPH-oxidase, NADPH
GLX351322
Cat.No: T8107
Synonym:
Target: NADPH-oxidase, NADPH
Cat. No. Product Name Target Signaling Pathways
T75504 Xanthine oxidase-IN-8

Others Others
Xanthine oxidase-IN-8 (Icarisids J) (Compound 7) 是一种 XOD 抑制剂,IC50值为 29.71 μM。
T75505 Xanthine oxidase-IN-9

Others Others
Xanthine oxidase-IN-9 (Icarisids E) (Compound 2),一种黄嘌呤氧化酶 (XOD) 高效抑制剂,具有31.81 μM 的 IC50 值。
T16685 Purpurogallin

红倍酚,红陪酚

Xanthine Oxidase Metabolism
Purpurogallin 是一种从栎属植物中提取的天然酚,具有显著的黄嘌呤氧化酶抑制作用,其IC50=0.2 µM,具有抗氧化和抗炎作用。
TN1120 Osthenol

MAO; Monoamine Oxidase Metabolism; Neuroscience
Osthenol 是一种前酰化香豆素,从独活干根中分离得到。它对重组 hMAO-A 具有潜在的选择性抑制作用,IC50=0.74 µM,对 hMAO-A 和 hMAO-B 表现出较高的选择性指数。它是一种可逆的,选择性的竞争性人单胺氧化酶-A(hMAO-A)抑制剂 (Ki=0.26 µM)。
T1694 Oxypurinol

Oxipurinol,羟基嘌呤

ROS; Xanthine Oxidase; Endogenous Metabolite Immunology/Inflammation; Metabolism
Oxypurinol 是一种黄嘌呤氧化酶 (xanthine oxidase) 抑制剂,是 Allopurinol 的主要特性代谢产物。它能够用于调节血尿酸水平,有潜力用于痛风的研究。
T2900 Paeonol

丹皮酚,Peonol

MAO; Autophagy; Monoamine Oxidase Autophagy; Metabolism; Neuroscience
Paeonol (Peonol) 是一种从牡丹中提取的活性物质,可抑制 MAO-A 和 MAO-B,IC50 分别为 54.6 μM 和 42.5 μM。
T3152 Harmol

哈尔酚(骆驼蓬醇),Methylpyridoindolol

Others; Monoamine Oxidase Neuroscience; Others
Harmol 一种 β-carboline 生物碱,是单胺氧化酶抑制剂,可用作分析参考标准品。
TN2004 Obtusin

1,7-二羟基-2,3,8-三甲氧基-6-甲基蒽-9,10-二酮,决明素

MAO; Monoamine Oxidase Metabolism; Neuroscience
Obtusin 是来自决明子种子,是一种高度选择性和竞争性的人单胺氧化酶-A 抑制剂,IC50=11.12 μM,Ki=6.15 μM。它在神经退行性疾病,尤其是焦虑和抑郁中起预防作用。
T4024 Norharmane

2-Azacarbazole,2,9-Diazafluorene,β-Carboline,去甲哈尔满

DNA; Endogenous Metabolite; Monoamine Oxidase DNA Damage/DNA Repair; Metabolism; Neuroscience
Norharmane (β-Carboline) 是一种有效的选择性单胺氧化酶 A (MAO-A) 抑制剂,Ki=3.34 μM。
T13475 β-Aminopropionitrile

3-氨基丙腈,3-Aminopropionitrile,BAPN

Others; Endogenous Metabolite Metabolism; Others
β-Aminopropionitrile (3-Aminopropionitrile) 是赖氨酰氧化酶的特异性抑制剂。
T3158 Harmane

Loturine,Harman,Aribine,哈尔满碱

Adrenergic Receptor; Monoamine Oxidase; Imidazoline Receptor GPCR/G Protein; Neuroscience
Harmane (Loturine) 是一种在咖啡和烟草烟雾中发现的 β-咔啉生物碱,是有效的神经毒素,可引起严重的动作震颤和精神病学表现。它还是选择性的单胺氧化酶抑制剂,具有致突变作用,对 MAO A/B 的 IC50值分别为 0.5 和 5 μM。
T6862 Isatin

Pseudoisatin,板蓝根,Indoline-2,3-dione,2,3-Indolinedione

Apoptosis; MAO; Monoamine Oxidase Apoptosis; Metabolism; Neuroscience
Isatin (2,3-Indolinedione) 是一种单胺氧化酶抑制剂,IC50为3 μM。它也可作为心钠肽刺激和一氧化氮刺激的鸟苷酸环化酶活性的拮抗剂,显示对血清素系统有影响。
T2858 Baicalein

5,6,7-Trihydroxyflavone,黄芩素,黄芩黄素

Ferroptosis; Influenza Virus; ROS; Xanthine Oxidase Apoptosis; Immunology/Inflammation; Metabolism; Microbiology/Virology
Baicalein (5,6,7-Trihydroxyflavone) 属于黄酮类天然产物,是一种黄嘌呤氧化酶抑制剂,一种 CYP2C9 的抑制剂,也是一种脯氨酰内肽酶抑制剂。Baicalein 具有抗肿瘤、抗炎、抗菌等活性。
TMA0958 Forsythoside F

连翘酯苷F,Arenarioside,三糖苯丙素苷

Xanthine Oxidase Metabolism
Forsythoside F (Arenarioside) 是一种黄嘌呤氧化酶 (xanthine oxidase) 抑制剂,具有抗高尿酸活性。
T10933 D-Cysteine

Endogenous Metabolite; Antibacterial Metabolism; Microbiology/Virology
D-Cysteine 是一种大肠杆菌生长的有力抑制剂,是半胱氨酸的 D 型异构体。它由 D-氨基酸氧化酶介导产生 H2S,是一种对抗小脑共济失调的神经保护剂。 D-半胱氨酸可以抑制由变形链球菌和链球菌血红蛋白形成的两种生物膜的生长和致龋性。
T3885 ROSIRIDIN

6'-O-Deacetylrosiridoside C,络塞定,(-)-Rosiridin

Others; Monoamine Oxidase Neuroscience; Others
Rosiridin (6'-O-Deacetylrosiridoside C) 能够抑制 MAO A 和 MAO B,有潜在的抑郁症和老年性痴呆作用。它在 10 μM 时对 MAO B 的抑制率为 83.8% (pIC50=5.38)。
T5S0734 Desmethoxyyangonin

Desmethoxy yangonin,去甲氧基醉椒素,Demethoxyyangonin,5,6-Dehydrokavain

Others; Monoamine Oxidase Neuroscience; Others
Desmethoxyyangonin (5,6-Dehydrokavain) 是一种MAO-B 可逆性抑制剂。
T2765 Rosmarinic acid

Labiatenic acid,迷迭香酸,Rosemary acid

Apoptosis; IκB/IKK; MAO; Endogenous Metabolite; Transferase; Monoamine Oxidase Apoptosis; Metabolism; Neuroscience; NF-κB
Rosmarinic acid (Labiatenic acid) 广泛存在植物中,具有抗氧化、抗炎和抗菌活性。它抑制 MAO-A,MAO-B 和 COMT,IC50分别为 50.1,184.6 和 26.7 μM。
T2971 Phytic acid

Inositol hexaphosphate,inositol hexakisphosphate,inositol polyphosphate,myo-Inositol, hexakis(dihydrogen phosphate),植酸,Fytic Acid

Xanthine Oxidase; Endogenous Metabolite Metabolism
Phytic acid (Fytic Acid) 是种子和谷粒的磷储存化合物。它被称为食品抑制剂,具有很强的螯合多价金属离子的能力,特别是钙,铁,锌和蛋白质残留物。它抑制超氧化物来源黄嘌呤氧化酶并具有抗氧化,抗炎以及神经保护作用。
T12564 Prudomestin

3,5,7-Trihydroxy-4',8-dimethoxyflavone,3,5,7-三羟基-8,4'-二甲氧基黄酮

Xanthine Oxidase Metabolism
Prudomestin (3,5,7-Trihydroxy-4',8-dimethoxyflavone) 是一种分离自 Prunus domestica 心材中,具有很强的黄嘌呤氧化酶(XO)抑制活性(IC50≈6 µM)。
T16527 Phytic acid dodecasodium salt hydrate

植酸十二钠盐,myo-Inositol, hexakis(dihydrogen phosphate) dodecasodium salt hydrate,Inositol hexaphosphate dodecasodium salt hydrate

Others; Xanthine Oxidase; Endogenous Metabolite Metabolism; Others
Phytic acid dodecasodium salt hydrate (myo-Inositol, hexakis(dihydrogen phosphate) dodecasodium salt hydrate) 是种子和谷物的磷储存化合物。 Phytic acid dodecasodium salt hydrate 抑制酶促超氧化物源黄嘌呤氧化酶,IC50 为 6 mM,并具有抗氧化、神经保护和抗炎作用。
T6S0923 Hypericin

Hypericine,金丝桃素,Cyclosan

Apoptosis; Antiviral; Influenza Virus; Tyrosine Kinases; Antibacterial; PKC Apoptosis; Chromatin/Epigenetic; Cytoskeletal Signaling; Immunology/Inflammation; Microbiology/Virology; Tyrosine Kinase/Adaptors
Hypericin (Cyclosan) 是贯叶连翘的提取物,有抗菌、抗病毒、抗肿瘤和抗抑郁作用。
T6391 Apocynin

香草乙酮,Acetovanillone,Acetoguaiacone,NSC 2146,罗布麻宁

Apoptosis; NADPH; Autophagy Apoptosis; Autophagy; Metabolism
Apocynin (NSC 2146) 是一种选择性NADPH-氧化酶抑制剂,IC50为10 μM。
T21213 Benzylurea

AI3-61350,Benzylcarbamide,Phenylmethylurea,苄脲,1-Benzylurea,N-Benzylurea

Others Others
Benzylurea (AI3-61350) 竞争性地抑制脱氢酶/细胞分裂素氧化酶。
T1363 N-Demethylricinine

4-Methoxy-2-oxo-1,2-dihydro-pyridine-3-carbonitrile,吉莫斯特中间体二

ROS Immunology/Inflammation
N-Demethylricinine (4-Methoxy-2-oxo-1,2-dihydro-pyridine-3-carbonitrile) 被报道为 xanthine oxidase 抑制剂。
T19302 D(-)-2-Aminobutyric acid

Endogenous Metabolite Metabolism
D(-)-2-Aminobutyric acid 是一种 D-氨基酸氧化酶的底物。
TN7211 Tetrahydroharmine

Leptaflorine

MAO Metabolism; Neuroscience
Tetrahydroharmine (Leptaflorine) 是一种天然产物,存在于植物Banisteriopsis caapi cultivar Da Vine 的茎和枝中。四氢骆驼蓬碱是一种Monoamine oxidase A 抑制剂。
Fr12415 Ethyl 4-hydroxyphenylacetate

Others Others
Ethyl 4-hydroxyphenylacetate 是单胺氧化酶 A 的选择性抑制剂。
TN1705 Glycyrrhisoflavone

MAO; Tyrosinase; NO Synthase; Immunology/Inflammation related Immunology/Inflammation; Metabolism; Neuroscience; Proteases/Proteasome
Glycyrrhisoflavone 是一种具有抗炎作用的酪氨酸酶抑制剂。 Glycyrrhisoflavone 抑制 α-葡萄糖苷酶和单胺氧化酶。
TQ0188 Miquelianin

槲皮素-3-O-葡萄糖醛酸苷,Quercetin 3-glucuronide,Quercetin 3-O-glucuronide

stilbene oxidase; Endogenous Metabolite Metabolism
Miquelianin (Quercetin 3-glucuronide) 是槲皮素的代谢产物,属于类黄酮化合物。
TN1002 Blumeatin

ROS Immunology/Inflammation
Blumeatin 是从Blumea balsamiferaDC 中分离得到,对 CCl4 和硫代乙酰胺 (TAA) 所致的肝损伤表现出保护活性。
T5300 Ammonium formate

甲酸铵,Formic acid ammonium salt

Others Others
Ammonium formate (Formic acid ammonium salt) 是最简单的羧酸。它通过抑制细胞色素氧化酶活性(电子传递链的末端电子受体)来负责代谢性酸中毒和破坏线粒体电子传递和能量产生。
T3750 4-Hydroxyacetophenone

对羟基苯乙酮,4-Acetylphenol,Piceol,p-Acetylphenol,4'-Hydroxyacetophenone

HBV; Xanthine Oxidase Metabolism; Microbiology/Virology
4-Hydroxyacetophenone (4-Acetylphenol) 是蒿属植物和木香属植物中的一种黄嘌呤氧化酶抑制剂,具有保肝促胆、抗乙型肝炎病毒和抗炎作用。
T3740 Isovanillin

3-羟基-4-甲氧基苯甲醛,3-Hydroxy-p-anisaldehyde,3-Hydroxy-4-methoxybenzaldehyde,5-Formylguaiacol

Others Others
Isovanillin (5-Formylguaiacol) 是一种醛氧化酶抑制剂,具有解痉挛和止泻活性。
T4716 Pyrrole-2-carboxylic acid

吡咯-2-羧酸,2-Pyrrolecarboxylic acid,Minaline

Endogenous Metabolite Metabolism
Pyrrole-2-carboxylic acid (Minaline) 是一种天然生物碱类,从海洋细菌Pelomonas puraquaesp. Nov 中分离得到。
TN2126 Quercetin-3-O-glucose-6''-acetate

6"-O-Acetylisoquercitrin,槲皮素-3-O-葡萄糖苷-6′′-乙酯

NADPH-oxidase; ROS; NADPH Immunology/Inflammation; Metabolism
Quercetin-3-O-glucose-6''-acetate (6"-O-Acetylisoquercitrin) 是 NADPH 氧化酶的抑制剂。 Quercetin-3-O-glucose-6''-acetate 具有抗氧化活性。
T21164 Sulfentrazone

甲磺草胺,FP-846

Others Others
Sulfentrazone (FP-846) 是苯基三唑啉酮除草剂,能够抑制原卟啉原氧化酶,导致脂质细胞膜破裂,可用于控制某些阔叶和禾本科杂草。
TC0022 Desoxypeganine

Deoxypeganine

AChE Neuroscience
Desoxypeganine (Deoxypeganine) 是胆碱酯酶的抑制剂。它优先作用于丁酰胆碱酯酶,作为单胺氧化酶 A 而不是单胺氧化酶 B 的选择性抑制剂。它在酒精滥用的药理学治疗中的潜在用途,以减少酒精滥用者的渴望和抑郁,并且也可能有用作为戒烟辅助。
TN1962 Myricetin 3-O-galactoside

Myricetin 3-O-beta-D-galactopyranoside

NOS; Xanthine Oxidase Immunology/Inflammation; Metabolism
Myricetin 3-O-galactoside (Myricetin 3-O-beta-D-galactopyranoside) 可抑制黄嘌呤氧化酶 (xanthine oxidase; XO) 活性,脂质过氧化并清除自由基。杨梅素3- o -半乳糖苷具有很多作用包括细胞毒性、抗氧化、抗基因毒性、抗感染性、抗炎作用和抗氧化活性,其主要作用是抑制诱导型一氧化氮合酶(iNOS)的合成。Myricetin 3-O-galactoside 抑制脂质过氧化的 IC50 为 160 μg/mL。
T13354 Xanthoangelol

Apoptosis; Monoamine Transporter; Antibacterial; AMPK Apoptosis; Chromatin/Epigenetic; Membrane transporter/Ion channel; Microbiology/Virology; PI3K/Akt/mTOR signaling
Xanthoangelol 可从 Angelica keiskei 中提取得到,对肥胖引起的炎症反应有抑制作用。Xanthoangelol 具有抗菌活性,对单胺氧化酶有抑制作用,还诱导神经母细胞瘤和白血病细胞凋亡。
T4455 DL-3-Phenyllactic acid

DL-3-苯乳酸,3-Phenyllactic acid,2-Hydroxy-3-phenylpropanoic acid

Others; Endogenous Metabolite; Antibacterial Metabolism; Microbiology/Virology; Others
DL-3-Phenyllactic acid (3-Phenyllactic acid) 是广谱抗菌化合物,对细菌和真菌具有活性。
T0617 Nicotinamide N-oxide

Nicotinamide-N-oxide,Nicotinamide 1-oxide,N-氧代烟酰胺,烟酰胺-N-氧化物,1-oxynicotinamide

c-Myc; Endogenous Metabolite; CXCR; Drug Metabolite Autophagy; Cell Cycle/Checkpoint; GPCR/G Protein; Immunology/Inflammation; Metabolism
Nicotinamide N-oxide (Nicotinamide 1-oxide) 是生物体内烟酰胺分解代谢物,是高效选择性CXCR2受体拮抗剂。
T10938 D-Kynurenine

D-尿嘧啶,(R)-2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid,ZINC901103

GPR; AhR; Endogenous Metabolite Endocrinology/Hormones; GPCR/G Protein; Immunology/Inflammation; Metabolism
D-Kynurenine (ZINC901103) 是 D-色氨酸的代谢物和 GPR109B 的激动剂。 D-Kynurenine 激活 AhR 并促进上皮细胞向间充质的转化。 D-Kynurenine 在 D-氨基酸氧化酶的荧光分析中用作底物。
TN1909 Malvidin-3-glucoside chloride

氯化锦葵色素-3-Β-葡糖苷,Malvidin-3-O-glucoside chloride,Oenin chloride

Others Others
Malvidin-3-glucoside chloride (Oenin chloride) 是一种主要的葡萄酒花青素,能够调节大脑突触可塑性和外周炎症,促进应激反应的发生。
T3933 Jatrorrhizine

Yatrorizine,neprotin,药根碱

MAO; 5-HT Receptor; Antibacterial; AChE GPCR/G Protein; Metabolism; Microbiology/Virology; Neuroscience
Jatrorrhizine (neprotin) 是一种从黄连中分离得到的生物碱,具有抗菌、抗氧化、抗疟原虫和神经保护活性。它通过抑制 uptake-2 transporter 的活性减少血清素和去甲肾上腺素的摄取。它是一种有口服活性的乙酰胆碱酯酶制剂。
TN1470 Cassiaside B2

决明子苷B2

Phosphatase; MAO; 5-HT Receptor GPCR/G Protein; Metabolism; Neuroscience
Cassiaside B2 是蛋白酪氨酸磷酸酶1B (PTP1B) 和人单胺氧化酶A (hMAO-A) 的抑制剂。Cassiaside B2是 5-HT2C 受体的激动剂, 具有抗过敏活性。Cassiaside B2 是萘吡喃酮参比提取物(NRE)的有效成分之一。
T3095 Tyramine

4-hydroxyphenethylamine,酪胺,para-tyramine,p-Tyramine,mydrial,Tocosine,Uteramine

MAO; Endogenous Metabolite Metabolism; Neuroscience
Tyramine (Uteramine) 是天然存在于体内或某些食物中的氨基酸。Tyramine 有助于调节血压。
T0626 Uric Acid

尿酸,2,6,8-Trioxopurine,2,6,8-Trioxypurine,2,6,8-Trihydroxypurine,Lithic acid,Urate

Reactive Oxygen Species; Endogenous Metabolite; Phosphorylase Immunology/Inflammation; Metabolism; NF-κB
Uric Acid (Lithic acid) 是一种重要的抗氧化剂。Uric acid 能清除活性氧(ROS) ,如单线态氧和过氧亚硝酸盐,抑制脂质过氧化。Uric acid 有助于维持血压的稳定和抗氧化应激。
T5S0281 Tubuloside A

NOS Immunology/Inflammation
Tubuloside A 是一种苯乙醇苷,具有抗氧化活性和保肝活性。
T4719 1,4-D-Gulonolactone

D-Gulonic acid γ-lactone,D-(-)-古洛糖酸-1,4-内酯

Others; Endogenous Metabolite Metabolism; Others
1,4-D-Gulonolactone (D-Gulonic acid γ-lactone) (也称为还原性抗坏血酸,RAA) 是 L-gulono-1,4-lactone oxidoreductase (EC 1.1.3.8)的底物,催化植物和动物中l -抗坏血酸(维生素C)生物合成的最后一步。enzyme L-Gulono-1,4-lactone oxidase 在容易患坏血病、缺乏维生素c的动物(如人类)中缺失。1,4-D-Gulonolactone 存在于人体血液中,并被用作比较运动引起的氧化应激变化的标志物之一。
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天然产物

Xanthine oxidase-IN-8
Cat.No: T75504
Synonym:
Target: Others
Xanthine oxidase-IN-9
Cat.No: T75505
Synonym:
Target: Others
Purpurogallin
Cat.No: T16685
Synonym: 红倍酚,红陪酚
Target: Xanthine Oxidase
Osthenol
Cat.No: TN1120
Synonym:
Target: MAO, Monoamine Oxidase
Oxypurinol
Cat.No: T1694
Synonym: Oxipurinol,羟基嘌呤
Target: ROS, Xanthine Oxidase, Endogenous Metabolite
Paeonol
Cat.No: T2900
Synonym: 丹皮酚,Peonol
Target: MAO, Autophagy, Monoamine Oxidase
Harmol
Cat.No: T3152
Synonym: 哈尔酚(骆驼蓬醇),Methylpyridoindolol
Target: Others, Monoamine Oxidase
Obtusin
Cat.No: TN2004
Synonym: 1,7-二羟基-2,3,8-三甲氧基-6-甲基蒽-9,10-二酮,决明素
Target: MAO, Monoamine Oxidase
Norharmane
Cat.No: T4024
Synonym: 2-Azacarbazole,2,9-Diazafluorene,β-Carboline,去甲哈尔满
Target: DNA, Endogenous Metabolite, Monoamine Oxidase
β-Aminopropionitrile
Cat.No: T13475
Synonym: 3-氨基丙腈,3-Aminopropionitrile,BAPN
Target: Others, Endogenous Metabolite
Harmane
Cat.No: T3158
Synonym: Loturine,Harman,Aribine,哈尔满碱
Target: Adrenergic Receptor, Monoamine Oxidase, Imidazoline Receptor
Isatin
Cat.No: T6862
Synonym: Pseudoisatin,板蓝根,Indoline-2,3-dione,2,3-Indolinedione
Target: Apoptosis, MAO, Monoamine Oxidase
Baicalein
Cat.No: T2858
Synonym: 5,6,7-Trihydroxyflavone,黄芩素,黄芩黄素
Target: Ferroptosis, Influenza Virus, ROS, Xanthine Oxidase
Forsythoside F
Cat.No: TMA0958
Synonym: 连翘酯苷F,Arenarioside,三糖苯丙素苷
Target: Xanthine Oxidase
D-Cysteine
Cat.No: T10933
Synonym:
Target: Endogenous Metabolite, Antibacterial
ROSIRIDIN
Cat.No: T3885
Synonym: 6'-O-Deacetylrosiridoside C,络塞定,(-)-Rosiridin
Target: Others, Monoamine Oxidase
Desmethoxyyangonin
Cat.No: T5S0734
Synonym: Desmethoxy yangonin,去甲氧基醉椒素,Demethoxyyangonin,5,6-Dehydrokavain
Target: Others, Monoamine Oxidase
Rosmarinic acid
Cat.No: T2765
Synonym: Labiatenic acid,迷迭香酸,Rosemary acid
Target: Apoptosis, IκB/IKK, MAO, Endogenous Metabolite, Transferase, Monoamine Oxidase
Phytic acid
Cat.No: T2971
Synonym: Inositol hexaphosphate,inositol hexakisphosphate,inositol polyphosphate,myo-Inositol, hexakis(dihydrogen phosphate),植酸,Fytic Acid
Target: Xanthine Oxidase, Endogenous Metabolite
Prudomestin
Cat.No: T12564
Synonym: 3,5,7-Trihydroxy-4',8-dimethoxyflavone,3,5,7-三羟基-8,4'-二甲氧基黄酮
Target: Xanthine Oxidase
Phytic acid dodecasodium salt hydrate
Cat.No: T16527
Synonym: 植酸十二钠盐,myo-Inositol, hexakis(dihydrogen phosphate) dodecasodium salt hydrate,Inositol hexaphosphate dodecasodium salt hydrate
Target: Others, Xanthine Oxidase, Endogenous Metabolite
Hypericin
Cat.No: T6S0923
Synonym: Hypericine,金丝桃素,Cyclosan
Target: Apoptosis, Antiviral, Influenza Virus, Tyrosine Kinases, Antibacterial, PKC
Apocynin
Cat.No: T6391
Synonym: 香草乙酮,Acetovanillone,Acetoguaiacone,NSC 2146,罗布麻宁
Target: Apoptosis, NADPH, Autophagy
Benzylurea
Cat.No: T21213
Synonym: AI3-61350,Benzylcarbamide,Phenylmethylurea,苄脲,1-Benzylurea,N-Benzylurea
Target: Others
N-Demethylricinine
Cat.No: T1363
Synonym: 4-Methoxy-2-oxo-1,2-dihydro-pyridine-3-carbonitrile,吉莫斯特中间体二
Target: ROS
D(-)-2-Aminobutyric acid
Cat.No: T19302
Synonym:
Target: Endogenous Metabolite
Tetrahydroharmine
Cat.No: TN7211
Synonym: Leptaflorine
Target: MAO
Ethyl 4-hydroxyphenylacetate
Cat.No: Fr12415
Synonym:
Target: Others
Glycyrrhisoflavone
Cat.No: TN1705
Synonym:
Target: MAO, Tyrosinase, NO Synthase, Immunology/Inflammation related
Miquelianin
Cat.No: TQ0188
Synonym: 槲皮素-3-O-葡萄糖醛酸苷,Quercetin 3-glucuronide,Quercetin 3-O-glucuronide
Target: stilbene oxidase, Endogenous Metabolite
Blumeatin
Cat.No: TN1002
Synonym:
Target: ROS
Ammonium formate
Cat.No: T5300
Synonym: 甲酸铵,Formic acid ammonium salt
Target: Others
4-Hydroxyacetophenone
Cat.No: T3750
Synonym: 对羟基苯乙酮,4-Acetylphenol,Piceol,p-Acetylphenol,4'-Hydroxyacetophenone
Target: HBV, Xanthine Oxidase
Isovanillin
Cat.No: T3740
Synonym: 3-羟基-4-甲氧基苯甲醛,3-Hydroxy-p-anisaldehyde,3-Hydroxy-4-methoxybenzaldehyde,5-Formylguaiacol
Target: Others
Pyrrole-2-carboxylic acid
Cat.No: T4716
Synonym: 吡咯-2-羧酸,2-Pyrrolecarboxylic acid,Minaline
Target: Endogenous Metabolite
Quercetin-3-O-glucose-6''-acetate
Cat.No: TN2126
Synonym: 6"-O-Acetylisoquercitrin,槲皮素-3-O-葡萄糖苷-6′′-乙酯
Target: NADPH-oxidase, ROS, NADPH
Sulfentrazone
Cat.No: T21164
Synonym: 甲磺草胺,FP-846
Target: Others
Desoxypeganine
Cat.No: TC0022
Synonym: Deoxypeganine
Target: AChE
Myricetin 3-O-galactoside
Cat.No: TN1962
Synonym: Myricetin 3-O-beta-D-galactopyranoside
Target: NOS, Xanthine Oxidase
Xanthoangelol
Cat.No: T13354
Synonym:
Target: Apoptosis, Monoamine Transporter, Antibacterial, AMPK
DL-3-Phenyllactic acid
Cat.No: T4455
Synonym: DL-3-苯乳酸,3-Phenyllactic acid,2-Hydroxy-3-phenylpropanoic acid
Target: Others, Endogenous Metabolite, Antibacterial
Nicotinamide N-oxide
Cat.No: T0617
Synonym: Nicotinamide-N-oxide,Nicotinamide 1-oxide,N-氧代烟酰胺,烟酰胺-N-氧化物,1-oxynicotinamide
Target: c-Myc, Endogenous Metabolite, CXCR, Drug Metabolite
D-Kynurenine
Cat.No: T10938
Synonym: D-尿嘧啶,(R)-2-Amino-4-(2-aminophenyl)-4-oxobutanoic acid,ZINC901103
Target: GPR, AhR, Endogenous Metabolite
Malvidin-3-glucoside chloride
Cat.No: TN1909
Synonym: 氯化锦葵色素-3-Β-葡糖苷,Malvidin-3-O-glucoside chloride,Oenin chloride
Target: Others
Jatrorrhizine
Cat.No: T3933
Synonym: Yatrorizine,neprotin,药根碱
Target: MAO, 5-HT Receptor, Antibacterial, AChE
Cassiaside B2
Cat.No: TN1470
Synonym: 决明子苷B2
Target: Phosphatase, MAO, 5-HT Receptor
Tyramine
Cat.No: T3095
Synonym: 4-hydroxyphenethylamine,酪胺,para-tyramine,p-Tyramine,mydrial,Tocosine,Uteramine
Target: MAO, Endogenous Metabolite
Uric Acid
Cat.No: T0626
Synonym: 尿酸,2,6,8-Trioxopurine,2,6,8-Trioxypurine,2,6,8-Trihydroxypurine,Lithic acid,Urate
Target: Reactive Oxygen Species, Endogenous Metabolite, Phosphorylase
Tubuloside A
Cat.No: T5S0281
Synonym:
Target: NOS
1,4-D-Gulonolactone
Cat.No: T4719
Synonym: D-Gulonic acid γ-lactone,D-(-)-古洛糖酸-1,4-内酯
Target: Others, Endogenous Metabolite
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Cat. No. Product Name Species Expression System
TMPY-00203 LOXL2 Protein, Mouse, Recombinant (His)

1110004B06Rik,4930526G11Rik,9430067E15Rik,lysyl oxidase<...

Mouse HEK293 Cells
Lysyl oxidase homolog 2, also known as Lysyl oxidase-like protein 2, Lysyl oxidase-related protein 2, Lysyl oxidase-related protein WS9-14 and LOXL2, is a secreted protein that belongs to the lysyl oxidase family. LOXL2 contains four SRCR domains. The lysyl oxidase family is made up of five members: lysyl oxidase (LOX) and lysyl oxidase-like 1-4 ( LOXL1, LOXL2, LOXL3, LOXL4 ). All members share conserved C-terminal catalytic domains that provide for lysyl oxidase or lysyl oxidase-like enzyme act...
TMPY-02481 ACOX1 Protein, Human, Recombinant (His)

PALMCOX,ACOX,SCOX,acyl-CoA oxidase 1, palmitoyl

Human Baculovirus Insect Cells
Peroxisomal acyl-coenzyme A oxidase 1(ACOX1 or AOX) is the first enzyme of the fatty acid beta-oxidation pathway and belongs to the Acyl-CoA oxidase family. Human liver peroxisomes contain two acyl-CoA oxidases, namely, palmitoyl-CoA oxidase (ACOX1/AOX) and a branched chain acyl-CoA oxidase. The palmitoyl-CoA oxidase (ACOX1/AOX) oxidizes the CoA esters of straight chain fatty acids and prostaglandins and donates electrons directly to molecular oxygen, thereby producing H2O2. Human ACOX1/AOX is a...
TMPH-00166 Glycine oxidase Protein, Bacillus subtilis, Recombinant (His & SUMO)

thiO,Glycine oxidase

Bacillus subtilis E. coli
Glycine oxidase Protein, Bacillus subtilis, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 56.9 kDa and the accession number is O31616.
TMPH-00103 Probable sarcosine oxidase Protein, Arabidopsis thaliana, Recombinant (His)

Probable sarcosine oxidase

Arabidopsis thaliana E. coli
N/A. Probable sarcosine oxidase Protein, Arabidopsis thaliana, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 49.7 kDa and the accession number is Q9SJA7.
TMPH-00453 L-ascorbate oxidase Protein, Cucurbita maxima, Recombinant (His & SUMO)

L-ascorbate oxidase,AAO

Cucurbita maxima E. coli
L-ascorbate oxidase Protein, Cucurbita maxima, Recombinant (His & SUMO) is expressed in E. coli.
TMPH-00824 Oxalate oxidase 1 Protein, Hordeum vulgare, Recombinant (His & Myc)

Oxalate oxidase 1,Germin

Hordeum vulgare E. coli
Releases hydrogen peroxide in the apoplast which may be important for cross-linking reactions in the cell wall biochemistry. May play an important role in several aspects of plant growth and defense mechanisms. Oxalate oxidase 1 Protein, Hordeum vulgare, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 28.2 kDa and the accession number is P45850.
TMPH-03485 L-saccharopine oxidase Protein, S. pombe, Recombinant (His & Myc)

L-saccharopine oxidase,fap2

Fission yeast E. coli
L-saccharopine oxidase Protein, S. pombe, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 52.2 kDa and the accession number is Q9UTM9.
TMPH-00757 Reticuline oxidase Protein, Eschscholzia californica, Recombinant (His)

BBE1,Tetrahydroprotoberberine synthase,Berberine bridge-form...

Eschscholzia californica E. coli
Essential to the formation of benzophenanthridine alkaloids in the response of plants to pathogenic attack. Catalyzes the stereospecific conversion of the N-methyl moiety of (S)-reticuline into the berberine bridge carbon of (S)-scoulerine.
TMPH-01225 DHODH Protein, Human, Recombinant (His)

DHOdehase,DHODH,Dihydroorotate oxidase,Dihydroorota...

Human E. coli
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
TMPH-00035 Polyphenol oxidase 2 Protein, Agaricus bisporus, Recombinant (His)

Tyrosinase 2,Cresolase 2,PPO2,Polyphenol oxidase 2

Agaricus bisporus Baculovirus Insect Cells
Copper-containing oxidase that catalyzes both the o-hydroxylation of monophenols and the subsequent oxidation of the resulting o-diphenols into reactive o-quinones, which evolve spontaneously to produce intermediates, which associate in dark brown pigments. Involved in the initial step of melanin synthesis. Melanins constitute a mechanism of defense and resistance to stress such as UV radiations, free radicals, gamma rays, dehydratation and extreme temperatures, and contribute to the fungal cell...
TMPH-00127 Glucose oxidase Protein, Aspergillus niger, Recombinant (His)

Glucose oxyhydrase,Glucose oxidase,gox,Beta-D-gluco...

Aspergillus niger Baculovirus Insect Cells
N/A. Glucose oxidase Protein, Aspergillus niger, Recombinant (His) is expressed in Baculovirus insect cells with N-10xHis tag. The predicted molecular weight is 65.6 kDa and the accession number is P13006.
TMPH-00036 Polyphenol oxidase 2 Protein, Agaricus bisporus, Recombinant (His & Myc)

Tyrosinase 2,Polyphenol oxidase 2,PPO2,Cresolase 2

Agaricus bisporus E. coli
Polyphenol oxidase 2 Protein, Agaricus bisporus, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 51.0 kDa and the accession number is O42713.
TMPH-00128 Glucose oxidase Protein, Aspergillus niger, Recombinant (E. coli, His)

gox,Glucose oxidase,Beta-D-glucose:oxygen 1-oxido-r...

Aspergillus niger E. coli
N/A. Glucose oxidase Protein, Aspergillus niger, Recombinant (E. coli, His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 68.6 kDa and the accession number is P13006.
TMPH-02474 HAOX1 Protein, Mouse, Recombinant (His)

Hao1,Glyoxylate oxidase,Glycolate oxidase,...

Mouse E. coli
Has 2-hydroxyacid oxidase activity. Most active on the 2-carbon substrate glycolate, but is also active on 2-hydroxy fatty acids, with high activity towards 2-hydroxy palmitate and 2-hydroxy octanoate. HAOX1 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 45.0 kDa and the accession number is Q9WU19.
TMPH-01968 LOX Protein, Human, Recombinant (His & MBP)

LOX,Protein-lysine 6-oxidase,Lysyl oxidase

Human Baculovirus Insect Cells
LOX Protein, Human, Recombinant (His & MBP) is expressed in Baculovirus.
TMPY-01770 HAO1 Protein, Human, Recombinant (His)

GOX1,hydroxyacid oxidase (glycolate oxidase

Human E. coli
Hydroxyacid oxidase 1, also known as Glycolate oxidase, HAO1, and GOX1, is a member of the FMN-dependent alpha-hydroxy acid dehydrogenase family. HAO1 / GOX1 has 2-hydroxyacid oxidase activity. It is most active on the 2-carbon substrate glycolate, but is also active on 2-hydroxy fatty acids, with high activity towards 2-hydroxy palmitate and 2-hydroxy octanoate. HAO1 / GOX1 is a liver-specific peroxisomal enzyme that oxidizes glycolate to glyoxylate with the concomitant production of H2O2. In H...
TMPH-01746 NOX4 Protein, Human, Recombinant (E. coli, His)

Kidney superoxide-producing NADPH oxidase,NOX4,NADP...

Human E. coli
NOX4 Protein, Human, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 28.8 kDa and the accession number is Q9NPH5.
TMPH-00913 AOX1 Protein, Human, Recombinant (His)

Aldehyde oxidase,AO,Azaheterocycle hydroxylase,Alde...

Human E. coli
AOX1 Protein, Human, Recombinant (His) is expressed in E. coli.
TMPH-01745 NOX4 Protein, Human, Recombinant (Cell-Free, His)

NOX4,Kidney oxidase-1,Renal NAD(P)H-oxidase

Human E. coli
NOX4 Protein, Human, Recombinant (Cell-Free, His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 69.8?kDa and the accession number is Q9NPH5.
TMPH-01969 LOX Protein, Human, Recombinant (His & Myc & SUMO)

Protein-lysine 6-oxidase,LOX,Lysyl oxidase

Human E. coli
Responsible for the post-translational oxidative deamination of peptidyl lysine residues in precursors to fibrous collagen and elastin. Regulator of Ras expression. May play a role in tumor suppression. Plays a role in the aortic wall architecture. LOX Protein, Human, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Myc tag. The predicted molecular weight is 49.0 kDa and the accession number is P28300.
TMPH-03359 LOX Protein, Rat, Recombinant (His)

Lysyl oxidase,Protein-lysine 6-oxidase,Lox

Rat E. coli
Responsible for the post-translational oxidative deamination of peptidyl lysine residues in precursors to fibrous collagen and elastin. Regulator of Ras expression. May play a role in tumor suppression. Plays a role in the aortic wall architecture. LOX Protein, Rat, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 33.0 kDa and the accession number is P16636.
TMPH-02825 ACOX1 Protein, Mouse, Recombinant (Myc)

AOX,Peroxisomal fatty acyl-CoA oxidase,EC:1.3.3.6,P...

Mouse E. coli
Catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. First enzyme of the fatty acid beta-oxidation pathway.; Shows highest activity against medium-chain fatty acyl-CoAs and activity decreases with increasing chain length.; Is active against a much broader range of substrates and shows activity towards very long-chain acyl-CoAs. Is twice as active as isoform 1 against 16-hydroxy-palmitoyl-CoA and is 25% more active against 1,16-hexadecanodioyl-CoA.
TMPH-00926 MAOB Protein, Human, Recombinant (His)

Amine oxidase [flavin-containing] B,Monoamine o...

Human E. coli
MAOB Protein, Human, Recombinant (His) is expressed in E. coli.
TMPH-01630 LOXL3 Protein, Human, Recombinant (GST & His)

LOXL3,Lysyl oxidase homolog 3,Lysyl oxidase

Human E. coli
LOXL3 Protein, Human, Recombinant (GST & His) is expressed in E. coli expression system with N-6xHis-GST tag. The predicted molecular weight is 55.7 kDa and the accession number is P58215.
TMPH-02863 LOX Protein, Mouse, Recombinant (His & Myc)

Ras excision protein,Protein-lysine 6-oxidase,Lysyl...

Mouse Baculovirus Insect Cells
Responsible for the post-translational oxidative deamination of peptidyl lysine residues in precursors to fibrous collagen and elastin. Regulator of Ras expression. May play a role in tumor suppression. Plays a role in the aortic wall architecture.
TMPH-02774 LOXL4 Protein, Mouse, Recombinant (His)

Loxl4,Lysyl oxidase-related protein C,Lysyl oxi...

Mouse E. coli
May modulate the formation of a collagenous extracellular matrix. LOXL4 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 85.9 kDa and the accession number is Q924C6.
TMPH-01744 NOX1 Protein, Human, Recombinant (His)

NADH/NADPH mitogenic oxidase subunit P65-MOX,NADPH ...

Human E. coli
NOH-1S is a voltage-gated proton channel that mediates the H(+) currents of resting phagocytes and other tissues. It participates in the regulation of cellular pH and is blocked by zinc. NOH-1L is a pyridine nucleotide-dependent oxidoreductase that generates superoxide and might conduct H(+) ions as part of its electron transport mechanism, whereas NOH-1S does not contain an electron transport chain. NOX1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-10xHis t...
TMPH-01180 COX5A Protein, Human, Recombinant (GST)

Cytochrome c oxidase polypeptide Va,Cytochrome c

Human E. coli
COX5A Protein, Human, Recombinant (GST) is expressed in E. coli.
TMPJ-00379 AOC3 Protein, Human, Recombinant (hFc)

SSAO,AOC3,Membrane primary amine oxidase,Copper ami...

Human HEK293 Cells
Membrane primary amine oxidase(AOC3), also known as vascular adhesion protein (VAP-1) and HPAO, this protein is a member of the semicarbazide-sensitive amine oxidase (SSAO) family. VAP-1 is a type 1 membrane-bound glycoprotein that has a distal adhesion domain and an enzymatically active amine oxidase site outside of the membrane, VAP-1 has adhesive properties, functional monoamine oxidase activity, and possibly plays a role in glucose handling, leukocyte trafficking, and migration during inflam...
TMPH-03639 COX7A1 Protein, Trachypithecus cristatu, Recombinant (hFc)

Cytochrome c oxidase subunit VIIa-H,COX7A1,Cytochro...

Trachypithecus cristatus HEK293 Cells
N/A. COX7A1 Protein, Trachypithecus cristatu, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 31.9 kDa and the accession number is Q9N234.
TMPH-01628 LOXL1 Protein, Human, Recombinant

Lysyl oxidase-like protein 1,Lysyl oxidase...

Human E. coli
Active on elastin and collagen substrates. LOXL1 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 53.0 kDa and the accession number is Q08397.
TMPH-01629 LOXL1 Protein, Human, Recombinant (His)

Lysyl oxidase-like protein 1,LOXL1,Lysyl oxidas...

Human E. coli
Active on elastin and collagen substrates.
TMPH-02154 SUOX Protein, Human, Recombinant (His & SUMO)

SUOX,Sulfite oxidase, mitochondrial

Human E. coli
N/A. SUOX Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 67.6 kDa and the accession number is P51687.
TMPH-01510 HAO2 Protein, Human, Recombinant (His & SUMO)

Long-chain L-2-hydroxy acid oxidase,Long chain alph...

Human E. coli
Catalyzes the oxidation of L-alpha-hydroxy acids as well as, more slowly, that of L-alpha-amino acids.
TMPJ-00380 AOC3 Protein, Human, Recombinant (His)

Membrane primary amine oxidase,HPAO,VAP-1,Semicarba...

Human HEK293 Cells
Vascular adhesion protein-1(VAP-1) is a copper amine oxidase with a topaquinone cofactor.VAP-1 is a type II integral membrane protein, but a soluble form of the enzyme is present in human serum, and its level increases in diabetes and some inflammatory liver diseases. VAP-1 catalyzes the oxidative deamination of small primary amines such as methylamine, benzylamine, and aminoacetone in a reaction that produces an aldehyde, ammonia, and H2O2. VAP-1 vascular expression is regulated at sites of inf...
TMPH-02617 COX5A Protein, Mouse, Recombinant (His & SUMO)

Cytochrome c oxidase subunit 5A, mitochondrial,COX5...

Mouse E. coli
Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over t...
TMPH-03130 Uricase Protein, Pig, Recombinant (His & SUMO)

Uricase,UOX,Urate oxidase

Sus scrofa (Pig) E. coli
Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin. Uricase Protein, Pig, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 51.0 kDa and the accession number is P16164.
TMPY-03511 COX5B Protein, Human, Recombinant (His)

COXVB,cytochrome c oxidase subunit Vb

Human E. coli
Cytochrome C oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nucl...
TMPH-01179 COX4I1 Protein, Human, Recombinant (His & SUMO)

Cytochrome c oxidase polypeptide IV,COX4I1,Cytochro...

Human E. coli
COX4I1 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli.
TMPH-02880 Renalase Protein, Mouse, Recombinant (His & SUMO)

Monoamine oxidase-C,Renalase,Rnls

Mouse E. coli
Renalase Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 52.0 kDa and the accession number is A7RDN6.
TMPJ-00853 DAO Protein, Human, Recombinant (His)

D-Amino-Acid Oxidase,DAMOX,DAAO,DAO

Human E. coli
D-Amino-Acid Oxidase (DAO) belongs to the DAMOX/DASOX family. DAO is a peroxisomal enzyme which founctions as a homodimer to oxidizes D-amino acids to the corresponding imino acids, producing ammonia and hydrogen peroxide. D-amino-acid oxidase regulates the level of the neuromodulator D-serine in the brain, has a high activity towards D-DOPA and contributes to dopamine synthesis. D-amino-acid oxidase could act as a detoxifying agent which removes D-amino acids accumulated during aging. It also a...
TMPH-03605 CHOD Protein, Streptomyces sp., Recombinant (GST)

choA,Cholesterol isomerase,CHOD,Cholesterol oxidase

Streptomyces E. coli
Bifunctional enzyme that catalyzes the oxidation of the 3-beta-hydroxy group of cholesterol and the isomerization of the double bond of the resulting product. CHOD Protein, Streptomyces sp., Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 81.9 kDa and the accession number is P12676.
TMPH-03276 DAO Protein, Rat, Recombinant (His & Myc)

D-amino-acid oxidase,Dao1,DAMOX,DAO,DAAO

Rat E. coli
Regulates the level of the neuromodulator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent which removes D-amino acids accumulated during aging. Acts on a variety of D-amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups. Does not act on acidic amino acids. DAO Protein, Rat, Recombinant (His & Myc) is expressed in E. coli expression sy...
TMPH-02621 DAO Protein, Mouse, Recombinant (His)

DAMOX,Dao1,DAO,DAAO,D-amino-acid oxidase

Mouse E. coli
Regulates the level of the neuromodulator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent which removes D-amino acids accumulated during aging. Acts on a variety of D-amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups. Does not act on acidic amino acids. DAO Protein, Mouse, Recombinant (His) is expressed in E. coli expression system...
TMPH-02627 DHODH Protein, Mouse, Recombinant (E. coli, His)

Dihydroorotate oxidase,DHODH,Dihydroorotate dehydro...

Mouse E. coli
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
TMPH-03278 DHODH Protein, Rat, Recombinant (His)

DHODH,DHOdehase,Dihydroorotate dehydrogenase (quinone), mito...

Rat E. coli
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
TMPJ-00938 4HPPD Protein, Human, Recombinant (His)

PPD,4HPPD,HPD,4-Hydroxyphenylpyruvate Dioxygenase,HPPDase,4-...

Human E. coli
4-Hydroxyphenylpyruvate Dioxygenase (4HPPD) belongs to the 4HPPD family. 4HPPD is a key enzyme in the degradation of tyrosine, which catalyzes the second reaction in the catabolism of tyrosine the conversation of 4-hydroxyphenylpyruvate to homogentisate. 4HPPD exists in homodimer forms, which uses zinc as a cofactor to catalyze the third step in the conversion of L-phenylalanine to fumarate and acetoacetic acid. When the active 4HPPD enzyme concentration is low in the human body, it results in h...
TMPH-02850 DHODH Protein, Mouse, Recombinant (His)

Dihydroorotate oxidase,Dihydroorotate dehydrogenase...

Mouse E. coli
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
TMPH-01501 HGD Protein, Human, Recombinant (His)

Homogentisicase,Homogentisic acid oxidase,Homogenti...

Human E. coli
HGD Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 54.0 kDa and the accession number is Q93099.
TMPY-00140 ABP1/AOC1 Protein, Human, Recombinant (His)

amine oxidase, copper containing 1,DAO,ABP1,ABP,KAO...

Human HEK293 Cells
Amine oxidase copper-containing 1 (AOC1; formerly known as amiloride-binding protein 1) is a secreted glycoprotein that catalyzes the degradation of putrescine and histamine. Polyamines and their diamine precursor putrescine are ubiquitous to all organisms and fulfill pivotal functions in cell growth and proliferation. That the Wilms tumor protein, WT1, which is necessary for normal kidney development, activates transcription of the AOC1 gene. Expression of a firefly luciferase reporter under co...
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重组蛋白

LOXL2 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-00203
Species: Mouse
Expression System: HEK293 Cells
ACOX1 Protein, Human, Recombinant (His)
Cat.No: TMPY-02481
Species: Human
Expression System: Baculovirus Insect Cells
Glycine oxidase Protein, Bacillus subtilis, Recombinant (His & SUMO)
Cat.No: TMPH-00166
Species: Bacillus subtilis
Expression System: E. coli
Probable sarcosine oxidase Protein, Arabidopsis thaliana, Recombinant (His)
Cat.No: TMPH-00103
Species: Arabidopsis thaliana
Expression System: E. coli
L-ascorbate oxidase Protein, Cucurbita maxima, Recombinant (His & SUMO)
Cat.No: TMPH-00453
Species: Cucurbita maxima
Expression System: E. coli
Oxalate oxidase 1 Protein, Hordeum vulgare, Recombinant (His & Myc)
Cat.No: TMPH-00824
Species: Hordeum vulgare
Expression System: E. coli
L-saccharopine oxidase Protein, S. pombe, Recombinant (His & Myc)
Cat.No: TMPH-03485
Species: Fission yeast
Expression System: E. coli
Reticuline oxidase Protein, Eschscholzia californica, Recombinant (His)
Cat.No: TMPH-00757
Species: Eschscholzia californica
Expression System: E. coli
DHODH Protein, Human, Recombinant (His)
Cat.No: TMPH-01225
Species: Human
Expression System: E. coli
Polyphenol oxidase 2 Protein, Agaricus bisporus, Recombinant (His)
Cat.No: TMPH-00035
Species: Agaricus bisporus
Expression System: Baculovirus Insect Cells
Glucose oxidase Protein, Aspergillus niger, Recombinant (His)
Cat.No: TMPH-00127
Species: Aspergillus niger
Expression System: Baculovirus Insect Cells
Polyphenol oxidase 2 Protein, Agaricus bisporus, Recombinant (His & Myc)
Cat.No: TMPH-00036
Species: Agaricus bisporus
Expression System: E. coli
Glucose oxidase Protein, Aspergillus niger, Recombinant (E. coli, His)
Cat.No: TMPH-00128
Species: Aspergillus niger
Expression System: E. coli
HAOX1 Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02474
Species: Mouse
Expression System: E. coli
LOX Protein, Human, Recombinant (His & MBP)
Cat.No: TMPH-01968
Species: Human
Expression System: Baculovirus Insect Cells
HAO1 Protein, Human, Recombinant (His)
Cat.No: TMPY-01770
Species: Human
Expression System: E. coli
NOX4 Protein, Human, Recombinant (E. coli, His)
Cat.No: TMPH-01746
Species: Human
Expression System: E. coli
AOX1 Protein, Human, Recombinant (His)
Cat.No: TMPH-00913
Species: Human
Expression System: E. coli
NOX4 Protein, Human, Recombinant (Cell-Free, His)
Cat.No: TMPH-01745
Species: Human
Expression System: E. coli
LOX Protein, Human, Recombinant (His & Myc & SUMO)
Cat.No: TMPH-01969
Species: Human
Expression System: E. coli
LOX Protein, Rat, Recombinant (His)
Cat.No: TMPH-03359
Species: Rat
Expression System: E. coli
ACOX1 Protein, Mouse, Recombinant (Myc)
Cat.No: TMPH-02825
Species: Mouse
Expression System: E. coli
MAOB Protein, Human, Recombinant (His)
Cat.No: TMPH-00926
Species: Human
Expression System: E. coli
LOXL3 Protein, Human, Recombinant (GST & His)
Cat.No: TMPH-01630
Species: Human
Expression System: E. coli
LOX Protein, Mouse, Recombinant (His & Myc)
Cat.No: TMPH-02863
Species: Mouse
Expression System: Baculovirus Insect Cells
LOXL4 Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02774
Species: Mouse
Expression System: E. coli
NOX1 Protein, Human, Recombinant (His)
Cat.No: TMPH-01744
Species: Human
Expression System: E. coli
COX5A Protein, Human, Recombinant (GST)
Cat.No: TMPH-01180
Species: Human
Expression System: E. coli
AOC3 Protein, Human, Recombinant (hFc)
Cat.No: TMPJ-00379
Species: Human
Expression System: HEK293 Cells
COX7A1 Protein, Trachypithecus cristatu, Recombinant (hFc)
Cat.No: TMPH-03639
Species: Trachypithecus cristatus
Expression System: HEK293 Cells
LOXL1 Protein, Human, Recombinant
Cat.No: TMPH-01628
Species: Human
Expression System: E. coli
LOXL1 Protein, Human, Recombinant (His)
Cat.No: TMPH-01629
Species: Human
Expression System: E. coli
SUOX Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-02154
Species: Human
Expression System: E. coli
HAO2 Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-01510
Species: Human
Expression System: E. coli
AOC3 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00380
Species: Human
Expression System: HEK293 Cells
COX5A Protein, Mouse, Recombinant (His & SUMO)
Cat.No: TMPH-02617
Species: Mouse
Expression System: E. coli
Uricase Protein, Pig, Recombinant (His & SUMO)
Cat.No: TMPH-03130
Species: Sus scrofa (Pig)
Expression System: E. coli
COX5B Protein, Human, Recombinant (His)
Cat.No: TMPY-03511
Species: Human
Expression System: E. coli
COX4I1 Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-01179
Species: Human
Expression System: E. coli
Renalase Protein, Mouse, Recombinant (His & SUMO)
Cat.No: TMPH-02880
Species: Mouse
Expression System: E. coli
DAO Protein, Human, Recombinant (His)
Cat.No: TMPJ-00853
Species: Human
Expression System: E. coli
CHOD Protein, Streptomyces sp., Recombinant (GST)
Cat.No: TMPH-03605
Species: Streptomyces
Expression System: E. coli
DAO Protein, Rat, Recombinant (His & Myc)
Cat.No: TMPH-03276
Species: Rat
Expression System: E. coli
DAO Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02621
Species: Mouse
Expression System: E. coli
DHODH Protein, Mouse, Recombinant (E. coli, His)
Cat.No: TMPH-02627
Species: Mouse
Expression System: E. coli
DHODH Protein, Rat, Recombinant (His)
Cat.No: TMPH-03278
Species: Rat
Expression System: E. coli
4HPPD Protein, Human, Recombinant (His)
Cat.No: TMPJ-00938
Species: Human
Expression System: E. coli
DHODH Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02850
Species: Mouse
Expression System: E. coli
HGD Protein, Human, Recombinant (His)
Cat.No: TMPH-01501
Species: Human
Expression System: E. coli
ABP1/AOC1 Protein, Human, Recombinant (His)
Cat.No: TMPY-00140
Species: Human
Expression System: HEK293 Cells
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Cat. No. Product Name Target Signaling Pathways
T11270 Febuxostat D9

非布司他D9

Others Others
Febuxostat D9 is deuterium labeled Febuxostat, which is a selective xanthine oxidase inhibitor with Ki of 0.6 nM.
TMID-0196 Allopurinol-d2

Allopurinol-d2 是 Allopurinol 的氘代化合物。Allopurinol 的 CAS 号为 315-30-0。Allopurinol 是一种黄嘌呤氧化酶(XO)抑制剂,IC50=7.82±0.12 μM。
T12693 Rasagiline 13C3 mesylate racemic

TVP1012 13C3 racemic,AGN1135 13C3 racemic

Others Others
Rasagiline 13C3 mesylate racemic is the deuterium labeled Rasagiline, which is an irreversible monoamine oxidase inhibitor.
TMID-0191 Moclobemide-d8

Moclobemide-d8 是 Moclobemide 的氘代化合物。Moclobemide 的 CAS 号为 71320-77-9。Moclobemide 是可逆的、可透过血脑屏障的单胺氧化酶 (MAO-A) 抑制剂,能够抑制 hMAO-A (IC50=6.061 μM)。它上调慢性应激小鼠海马祖细胞的增殖。
T12701 (rel)-Tranylcypromine D5 hydrochloride

2-Phenylcyclopropylamine D5 hydrochloride

Histone Demethylase Chromatin/Epigenetic
(rel)-Tranylcypromine D5 hydrochloride is a deuterium labeled (rel)-Tranylcypromine hydrochloride. (rel)-Tranylcypromine hydrochloride is an irreversible, nonselective inhibitor of monoamine oxidase (MAO) used in the treatment of depression.
TMIH-0352 Moclobemide-d4

Moclobemide-d4 是 Moclobemide 的氘代化合物。Moclobemide 的 CAS 号为 71320-77-9。Moclobemide 是可逆的、可透过血脑屏障的单胺氧化酶 (MAO-A) 抑制剂,能够抑制 hMAO-A (IC50=6.061 μM)。它上调慢性应激小鼠海马祖细胞的增殖。
TMIJ-0161 Febuxostat-d7

Febuxostat-d7 是 Febuxostat 的氘代化合物。Febuxostat 的 CAS 号为 144060-53-7。Febuxostat 是一种选择性黄嘌呤氧化酶(XO)抑制剂,Ki=0.6 nM。
TMIH-0244 Fomesafen-d3

Fomesafen-d3 是 Fomesafen 的氘代化合物。Fomesafen 的 CAS 号为 72178-02-0。Fomesafen 是原卟啉原 IX 氧化酶的选择性抑制剂。Fomesafen用作除草剂,具有低毒性和高选择性的优点。
TMIJ-0129 Topiroxostat-d4

Topiroxostat-d4 是 Topiroxostat 的氘代化合物。Topiroxostat 的 CAS 号为 577778-58-6。Topiroxostat 是一种有效的口服黄嘌呤氧化还原酶 (XOR) 抑制剂,IC50=5.3 nM,Ki=5.7 nM。它还表现出弱的CYP3A4抑制活性 (18.6%)。它有用于高尿酸血症的研究潜力。
T70174 Pirlindole-d4 HCl

Pirlindole-d4 is intended for use as an internal standard for the quantification of pirlindole by GC- or LC-MS. Pirlindole is a selective and reversible monoamine oxidase A (MAO-A) inhibitor. It is selective for MAO-A over MAO-B. In rats, it reverses the depressive-like effects induced by chronic mild stress (CMS), increases proliferation of hippocampal neural progenitor cells, and reverses dendritic atrophy in granule neurons. Pirlindole is also an inhibitor of enterovirus-D68 and coxsackieviru...
T36903 Rasagiline-13C3 (mesylate)

Rasagiline-13C3 (mesylate)

Rasagiline-13C3is intended for use as an internal standard for the quantification of rasagiline by GC- or LC-MS. Rasagiline is an inhibitor of monoamine oxidase B (MAO-B; IC50= 4.43 nM for the rat brain enzyme).1It is selective for MAO-B over MAO-A (IC50= 412 nM for the rat brain enzyme). It inhibits serum and NGF withdrawal-induced apoptosis of PC12 cells when used at concentrations ranging from 0.01 to 100 μM.2Rasagiline inhibits rat brain MAO-Bin vivo(ED50= 0.1 mg/kg).1It reduces cerebral ede...
TMID-0122 Uric acid-13C-15N2

Uric acid-13C-15N2 是 Uric acid 的 13C 和 15 N 的标记化合物。Uric acid 的 CAS 号为 69-93-2。Uric acid 是一种重要的抗氧化剂。Uric acid 能清除活性氧(ROS) ,如单线态氧和过氧亚硝酸盐,抑制脂质过氧化。Uric acid 有助于维持血压的稳定和抗氧化应激。
T35520 Aflatoxin G1-13C17

Aflatoxin G1-13C17

Aflatoxin G1-13C17is intended for use as an internal standard for the quantification of aflatoxin G1by GC- or LC-MS. Aflatoxin G1is a mycotoxin that has been found inA. terricola.1In vivo, aflatoxin G1is lethal to ducklings (LD50= 1.18 mg/kg).2It induces hepatocellular carcinoma tumor formation and lethality in rats when administered at doses of 1.4 and 3 mg/animal, respectively. Aflatoxin G1also inhibits liver and kidney succinate dehydrogenase and fumarase, as well as kidney cytochrome oxidase...
T71328 Theobromine-d6

Theobromine-d6 is intended for use as an internal standard for the quantification of theobromine by GC- or LC-MS. Theobromine is a methylxanthine alkaloid and derivative of caffeine that has been found in cocoa beans and has diverse biological activities. It is an adenosine A1 receptor antagonist. Theobromine increases AMPK phosphorylation and inhibits adipocyte differentiation, ERK and JNK phosphorylation, and IL-6 and TNF-α production in 3T3-L1 preadipocytes cultured in differentiation medium....
TMID-0056 (±)-Mandelic-2,3,4,5,6-d5 Acid

(±)-Mandelic-2,3,4,5,6-d5 Acid 是 (±)-Mandelic Acid 的氘代化合物。(±)-Mandelic Acid 的 CAS 号为 90-64-2。DL-Mandelic acid 是一种 α-羟基羧酸,有抗菌活性,广泛用作医药和精细化学品的中间体,已用于研究尿路感染和阴道滴虫病,还具有较高的精子固定活性和较低的阴道刺激性。
TMID-0167 6-Hydroxypurine-d4

6-Hydroxypurine-d4 是 6-Hydroxypurine 的氘代化合物。6-Hydroxypurine 的 CAS 号为 68-94-0。Hypoxanthine,也被称为 purine-6-ol 或 Hyp,属于嘌呤类有机化合物。Hypoxanthine 是一种天然存在的嘌呤衍生物,是腺苷代谢和核苷酸补救途径形成核酸的反应中间体。在正常情况下,Hypoxanthine 很容易转化为尿酸。Hypoxanthine 首先被氧化为黄嘌呤,黄嘌呤再被黄嘌呤氧化酶氧化为尿酸。

同位素标记化合物

Febuxostat D9
Cat.No: T11270
Synonym: 非布司他D9
Target: Others
Allopurinol-d2
Cat.No: TMID-0196
Synonym:
Target:
Rasagiline 13C3 mesylate racemic
Cat.No: T12693
Synonym: TVP1012 13C3 racemic,AGN1135 13C3 racemic
Target: Others
Moclobemide-d8
Cat.No: TMID-0191
Synonym:
Target:
(rel)-Tranylcypromine D5 hydrochloride
Cat.No: T12701
Synonym: 2-Phenylcyclopropylamine D5 hydrochloride
Target: Histone Demethylase
Moclobemide-d4
Cat.No: TMIH-0352
Synonym:
Target:
Febuxostat-d7
Cat.No: TMIJ-0161
Synonym:
Target:
Fomesafen-d3
Cat.No: TMIH-0244
Synonym:
Target:
Topiroxostat-d4
Cat.No: TMIJ-0129
Synonym:
Target:
Pirlindole-d4 HCl
Cat.No: T70174
Synonym:
Target:
Rasagiline-13C3 (mesylate)
Cat.No: T36903
Synonym: Rasagiline-13C3 (mesylate)
Target:
Uric acid-13C-15N2
Cat.No: TMID-0122
Synonym:
Target:
Aflatoxin G1-13C17
Cat.No: T35520
Synonym: Aflatoxin G1-13C17
Target:
Theobromine-d6
Cat.No: T71328
Synonym:
Target:
(±)-Mandelic-2,3,4,5,6-d5 Acid
Cat.No: TMID-0056
Synonym:
Target:
6-Hydroxypurine-d4
Cat.No: TMID-0167
Synonym:
Target:
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