购物车
- 全部删除
- 您的购物车当前为空
Tranylcypromine hemisulfate (Tranylcypromine Sulfate) 是单胺氧化酶(MAO) 和赖氨酸特异性去甲基化酶 1 (LSD1) 的抑制剂,可用于研究抑郁症和子宫内膜异位症。
Tranylcypromine hemisulfate (Tranylcypromine Sulfate) 是单胺氧化酶(MAO) 和赖氨酸特异性去甲基化酶 1 (LSD1) 的抑制剂,可用于研究抑郁症和子宫内膜异位症。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
100 mg | ¥ 415 | 现货 |
产品描述 | Tranylcypromine hemisulfate (Tranylcypromine Sulfate) is an inhibitor of monoamine oxidase (MAO) and lysine-specific demethylase 1 (LSD1) with a rapid onset of activity. |
体内活性 | Tranylcypromine通过诱导转录和表观遗传调节作用,通过促进p38 MAPKγ活性,从而调控了RGC存活。因此,抑制LSD1活性的药理治疗可能是治疗神经退行性疾病的一种新颖治疗策略[1]。 |
动物实验 | The authors evaluated whether tranylcypromine contributes to neuronal survival following stress-induced damage using primary cultured rat RGCs and in vivo N-methyl-D-aspartate (NMDA)-induced excitotoxicity.?Additionally, the molecules associated with tranylcypromine treatment were assessed by microarray and immunoblot analysis[1]. |
别名 | 反苯环丙胺半硫酸盐, Tranylcypromine Sulfate, Tranylcypromine (hemisulfate) |
分子量 | 182.23 |
分子式 | C9H11N 1/2H2SO4 |
CAS No. | 13492-01-8 |
存储 | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
溶解度信息 | H2O: 10 mg/mL (54.8 mM), Sonication is recommended. DMSO: 3.33 mg/mL (18 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
溶液配制表 | ||||||||||||||||||||||||||||||||||||
DMSO/H2O
H2O
|
版权所有©2015-2024 TargetMol Chemicals Inc.保留所有权利.