|
TMPH-03291
|
FABP3 Protein, Rat, Recombinant (His & Myc)
Fabp3,Fatty acid-binding protein 3,Heart-type fatty...
|
Rat
|
HEK293 Cells
|
|
FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. |
|
TMPJ-00785
|
FABP3 Protein, Human, Recombinant (His)
H-FABP,FABP11,Fatty Acid-Binding Protein Heart,MDGI...
|
Human
|
E. coli
|
|
Fatty Acid Binding Protein 3 (FABP3) is a small cytoplasmic protein (15 kDa) that is released from cardiac myocytes following an ischemic episode. Like the nine other distinct FABPs that have been identified, FABP3 is involved in active fatty acid metabolism where it transports fatty acids from the cell membrane to mitochondria for oxidation. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-types. They form 14-15 kDa proteins and are thought to p... |
|
TMPH-02055
|
RBPMS Protein, Human, Recombinant (His & Myc)
RBPMS,Heart and RRM expressed sequence,RNA-binding ...
|
Human
|
E. coli
|
|
Acts as a coactivator of transcriptional activity. Required to increase TGFB1/Smad-mediated transactivation. Acts through SMAD2, SMAD3 and SMAD4 to increase transcriptional activity. Increases phosphorylation of SMAD2 and SMAD3 on their C-terminal SSXS motif, possibly through recruitment of TGFBR1. Promotes the nuclear accumulation of SMAD2, SMAD3 and SMAD4 proteins. Binds to poly(A) RNA. RBPMS Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-... |
|
TMPH-01372
|
GJA1 Protein, Human, Recombinant (His)
Gap junction 43 kDa heart protein,GJA1,Connexin-43,...
|
Human
|
E. coli
|
|
GJA1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 20.3 kDa and the accession number is P17302. |
|
TMPH-02669
|
GJA1 Protein, Mouse, Recombinant (His & Myc)
Gap junction 43 kDa heart protein,Gja1,Gap junction...
|
Mouse
|
Baculovirus Insect Cells
|
|
Gap junction protein that acts as a regulator of bladder capacity. A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. Negative regulator of bladder functional capacity: acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles to cholinergic neural stimuli and causing them to contract. May play a role in cell growth inhibi... |
|
TMPJ-00797
|
LDHB Protein, Human, Recombinant (His)
LDH-B,Renal Carcinoma Antigen NY-REN-46,LDH-H,LDH Heart<...
|
Human
|
E. coli
|
|
L-Lactate Dehydrogenase B Chain (LDH-B) is a member of the lactate dehydrogenase family that consists of three members, LDH-A, LDH-B and LDH-C; members of this family function as powerful markers for germ cell tumors. LDH-B is an oxidoreductase that catalyzes the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+. It converts pyruvate to lactate when oxygen is absent or in short supply and it performs the reverse reaction during the Cori cycle in the liver.... |
|
TMPH-03639
|
COX7A1 Protein, Trachypithecus cristatu, Recombinant (hFc)
Cytochrome c oxidase subunit VIIa-H,COX7A1,Cytochrome c oxid...
|
Trachypithecus cristatus
|
HEK293 Cells
|
|
N/A. COX7A1 Protein, Trachypithecus cristatu, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 31.9 kDa and the accession number is Q9N234. |
|
TMPH-00986
|
CORIN Protein, Human, Recombinant (His)
TMPRSS10,Pro-ANP-converting enzyme,Heart-specific s...
|
Human
|
E. coli
|
|
CORIN Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 16.0 kDa and the accession number is Q9Y5Q5. |
|
TMPY-00117
|
FGF-16 Protein, Human, Cynomolgus, Recombinant
fibroblast growth factor 16
|
Human,Cynomolgus
|
Baculovirus Insect Cells
|
|
Fibroblast growth factor 16 (FGF16) is preferentially expressed in the heart after birth, suggesting its regulation is associated with tissue-specific chromatin remodeling and DNA-protein interactions. Mutation of the MEF2 site resulted in a blunting of FGF16 promoter activity in transfected neonatal rat cardiac myocytes, that chromatin remodeling and MEF2 binding in the FGF16 promoter contribute to expression in the postnatal heart. FGF16 involvement in the fine tuning of the human skeleton of ... |
|
TMPY-04544
|
MEK2 Protein, Human, Recombinant (GST)
mitogen-activated protein kinase kinase 2,FLJ26075,MKK2,CFC4...
|
Human
|
Baculovirus Insect Cells
|
|
Dual specificity mitogen-activated protein kinase kinase 2, also known as MAP kinase kinase 2, MAPKK2, ERK activator kinase 2, MAPK / ERK kinase 2, MEK2 and MAP2K2, is a member of the protein kinase superfamily, STE Ser/Thr protein kinase family and MAP kinase kinase subfamily. MAP2K2 / MEK2 contains one protein kinase domain. MEK1 and MEK2 (also known as MAP2K1 and MAP2K2, respectively) are evolutionarily conserved, dual-specificity kinases that mediate Erk1 and Erk2 activation during adhesion ... |
|
TMPY-00545
|
Dermcidin Protein, Human, Recombinant (hFc)
AIDD,PIF,HCAP,dermcidin,DCD-1,DSEP
|
Human
|
HEK293 Cells
|
|
Hepatocellular carcinoma (HCC) is a major contributor to cancer-related deaths due to its often late stage diagnosis, and dermcidin (DCD) may have the potential to be used as a serum biomarker for HCC for more timely diagnoses. Human dermcidin (DCD) is an antimicrobial peptide secreted constitutively by sweat glands. And the role of DCD in ischemic heart disease has drawn increasing attention in particular its relationship with insulin secretion and glycemic control, nitric oxide (NO) synthesis ... |
|
TMPJ-00261
|
TGF beta 2 Protein, Mouse/Rat, Recombinant
transforming growth factor β-2,BSC-1 cell growth inhibitor,G...
|
Mouse,Rat
|
HEK293 Cells
|
|
Transforming growth factor beta 2 (TGF-β2) is a member of TGF-beta superfamily that shares a characteristic cysteine knot structure. Mice with TGF-β2 gene deletion show defects in development of cardiac, lung, craniofacial, limb, spinal column, eye, inner ear and urogenital systems. All TGF-β isoforms signal via the same heteromeric receptor complex, consisting of a ligand binding TGF-β receptor type II (TβR-II), and a TGF-β receptor type I (TβR-I). Signal transduction from the receptor to the n... |
|
TMPJ-00562
|
PDGF-BB Protein, Mouse, Recombinant (His)
PDGFBB,PDGF-BB,血小板源生长因子
|
Mouse
|
E. coli
|
|
Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF growth factor family. Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. PDGFB can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. As growth factor，it plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival... |
|
TMPY-05510
|
BDNF Protein, Mouse, Recombinant (His)
brain-derived neurotrophic factor
|
Mouse
|
HEK293 Cells
|
|
BDNF is a member of thenerve growth factorfamily. It is highly expressed in hippocampus, amygdala, cerebral cortex and cerebellum. It also can be detected in heart, lung, skeletal muscle, testis, prostate and placenta. BDNF is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. During development, BDNF promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. It participates in axonal growth,... |
|
TMPJ-01204
|
TPSAB1 Protein, Human, Recombinant (His)
TPS1,tryptase alpha/beta 1,TPS2,tryptase α/β1,tryptase α/β 1...
|
Human
|
HEK293 Cells
|
|
Tryptases are serine proteases with trypsin-like specificity. Together with chymases and Cathepsin G, tryptases are important players in mast cell mediation of inflammatory and allergic responses. Tryptase alpha/beta-1(TPSAB1), also known as mast cell protease 7 (MCPT7), it exhibits anticoagulant activity due to its ability to degrade fibrinogen in the presence of a diverse array of protease inhibitors in plasma. The two Isoform 1 and isoform 2 are expressed in lung, stomach, spleen, heart and s... |
|
TMPJ-01011
|
FGF-9 Protein, Mouse, Recombinant (His)
heparin-binding growth factor-9,GAF,HBGF-9,Glia-activating f...
|
Mouse
|
E. coli
|
|
Fibroblast growth factor-9 (FGF-9) is an approximately 26 kDa secreted glycoprotein of the FGF family. Secreted mouse FGF-9 lacks the N-terminal 1-3 aa and shares >98% sequence identity with rat, human, equine, porcine and bovine FGF-9. FGF-9 plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. In the mouse embryo the location and timing of FGF-9 expression affects development of the skeleton, cerebellum, lungs, heart, v... |
|
TMPY-01085
|
VLDLR Protein, Human, Recombinant (His)
VLDLRCH,CAMRQ1,CHRMQ1,very low density lipoprotein receptor,...
|
Human
|
HEK293 Cells
|
|
The very low density lipoprotein receptor, known as VLDLR, is a single-pass type 1 integral membrance protein and a member of the LDL receptor family. This receptor family includes LDL receptor, LRP, megalin, VLDLR and ApoER2, and is characterized by a cluster of cysteine-rich class A repeats, epidermal growth factor (EGF)-like repeats, YWTD repeats and an O-linked sugar sdomain. VLDLR contains 3 EGF-like domains, 8 LDL-receptor class A domains, as well as 6 LDL-receptor class B repeats, and is ... |
|
TMPJ-00412
|
VEGFR1/FLT-1 Protein, Human, Recombinant (hFc)
Vascular endothelial growth factor receptor 1,Vascular perme...
|
Human
|
HEK293 Cells
|
|
Human Vascular endothelial growth factor receptor 1(VEGFR-1, FLT-1) is a member of the the class III subfamily of receptor tyrosine kinases (RTKs) and Tyr protein kinase family and CSF-1/PDGF receptor subfamily. VEGFR-1 is widely expressed in human tissues including normal lung, placenta, liver, kidney, heart and brain tissues. It is specifically expressed in most of the vascular endothelial cellsand peripheral blood monocytes. VEGFR-1 contains seven Ig-like C2-type domains and one protein kinas... |
|
TMPJ-00042
|
TSLP Protein, Human, Recombinant
TSLP,Thymic stromal lymphopoietin
|
Human
|
E. coli
|
|
Thymic stromal lymphopoietin (TSLP) is a novel member of the hemopoietic cytokine family that promotes the development of B cells and shares overlapping activity with IL-7. The human TSLP protein comprises a 28 amino acids (aa) signal sequence and 131 aa mature region. Human TSLP has two isoforms lfTSLP and sfTSLP produced by alternative splicing . lfTSLP is expressed in a number of tissues including heart, liver and prostate, and sfTSLP (63aa) is predominantly expressed in keratinocytes of oral... |
|
TMPH-00780
|
CACNA1C Protein, Guinea Pig, Recombinant (His)
CACNA1C,CACNL1A1,CACH2,CACN2,Voltage-dependent L-type calciu...
|
Guinea pig
|
E. coli
|
|
Pore-forming, alpha-1C subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents. Mediates influx of calcium ions into the cytoplasm, and thereby triggers calcium release from the sarcoplasm. Plays an important role in excitation-contraction coupling in the heart. Required for normal heart development and normal regulation of heart rhythm. Required for normal contraction of smooth muscle cells in blood vessels and in the intestine. Essential for normal blood pressur... |
|
TMPJ-00875
|
NPPB Protein, Human, Recombinant (His)
NPPB,γ-Brain Natriuretic Peptide,Gamma-Brain Natriuretic Pep...
|
Human
|
E. coli
|
|
Human Natriuretic peptides B acts as a cardiac hormone; it is associated with many biological actions, such as diuresis, natriuresis, vasorelaxation, which inhibits the secretion of rennin and aldosterone. It acts as a paracrine antifibrotic factor in the heart. Natriuretic peptides B can help restore the body balance of salt and water, improves the heart function. Natriuretic peptides B binds and stimulates the cGMP production of the NPR1 receptor and binds the clearance receptor NPR3. |
|
TMPY-03458
|
Sorcin/SRI Protein, Human, Recombinant
sorcin,SCN,CP22,V19,CP-22
|
Human
|
Baculovirus Insect Cells
|
|
Sorcin was originally identified in multidrug-resistant cells. It is a calcium-binding protein. Sorcin modulates excitation-contraction coupling in the heart, contributes to calcium homeostasis in the heart sarcoplasmic reticulum. Sorcin is overexpressed in the multi-drug resistant chinese hamster ovary cell line CHRC5 and a variety of multidrug-resistant tumor cell lines, but overexpression is not a sufficient or necessary condition for the acquisition of the multidrug-resistant phenotype. Sorc... |
|
TMPY-03267
|
Sorcin/SRI Protein, Human, Recombinant (His & GST)
CP-22,CP22,sorcin,V19,SCN
|
Human
|
Baculovirus Insect Cells
|
|
Sorcin was originally identified in multidrug-resistant cells. It is a calcium-binding protein. Sorcin modulates excitation-contraction coupling in the heart, contributes to calcium homeostasis in the heart sarcoplasmic reticulum. Sorcin is overexpressed in the multi-drug resistant chinese hamster ovary cell line CHRC5 and a variety of multidrug-resistant tumor cell lines, but overexpression is not a sufficient or necessary condition for the acquisition of the multidrug-resistant phenotype. Sorc... |
|
TMPJ-01408
|
HDGFRP3 Protein, Human, Recombinant (His)
HDGF2,HRP-3,HDGF-2,Hepatoma-Derived Growth Factor-Related Pr...
|
Human
|
HEK293 Cells
|
|
Hepatoma-Derived Growth Factor-Related Protein 3 (HDGFRP3) belongs to the HDGF family. HDGFRP3 can be found in testis, heart, spinal cord and brain. HDGFRP3 localizes to the nucleus and contains one PWWP domain. HDGFRP3 enhances DNA synthesis and may have a role in cell proliferation. |
|
TMPJ-01248
|
Cytoglobin/CYGB Protein, Human, Recombinant (His)
Stellate Cell Activation-Associated Protein,Cytoglobin,CYGB,...
|
Human
|
E. coli
|
|
Cytoglobin is a ubiquitously globin protein that belongs to the globin family. The highest expressed in heart, stomach, bladder and small intestine. CYGB acts a protector under conditions of oxidative stress. CYGB may be involved in intracellular oxygen storage or transfer, modulates oxygen and nitric oxide metabolism or scavenging free radicals within a cell. |
|
TMPJ-00386
|
ACE2/ACEH Protein, Human, Recombinant (HEK293, His & Avi), Biotinylated
Metalloprotease MPROT15,ACEH,Angiotensin-Converting Enzyme H...
|
Human
|
HEK293 Cells
|
|
Angiotensin-Converting Enzyme 2 (ACE-2) is an integral membrane protein and a zinc metalloprotease of the ACE family, the ACE family includes somatic and germinal ACE. ACE-2 cleaves angiotensins I and II as a carboxypeptidase, ACE-2 converts angiotensin I to angiotensin 1-9, and angiotensin II to angiotensin 1-7. ACE-2 is also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. ACE-2 can be high expressed in testis, kidney and heart, in colon, small intestine and ovary at moderate... |
|
TMPK-00695
|
N Cadherin Protein, Human, Recombinant (hFc)
CDHN,Neural cadherin,CDH2,N-cadherin,CDw325,CD325,NCAD
|
Human
|
HEK293 Cells
|
|
Neural (N)-cadherin is a calcium-dependent single-chain transmembrane glycoprotein that mediates homotypic and heterotypic cell-cell adhesion. As an important member of the cadherin family, N-cadherin plays an important role in the developmental and functional regulation of the nervous system, brain, heart, skeletal muscles, blood vessels and hematopoietic microenvironment. |
|
TMPJ-01319
|
TINAGL1 Protein, Human, Recombinant (His)
LCN7,Tubulointerstitial nephritis antigen-like (TINAGL1),Oxi...
|
Human
|
HEK293 Cells
|
|
TINAGL1 is a secreted protein and contains one SMB (somatomedin-B) domain. TINAGL1 is expressed in aorta, lymph nodes, heart, bone marrow, placenta, lung, kidney, skeletal muscle, pancreas, thyroid, adrenal gland and so on. TINAGL1 may be implicated in the adrenocortical zonation and in mechanisms for repressing the CYP11B1 gene expression in adrenocortical cells. |
|
TMPY-00569
|
B3GAT3 Protein, Human, Recombinant (His)
beta-1,3-glucuronyltransferase 3,glcUAT-I,GLCATI,β-1,3-glucu...
|
Human
|
E. coli
|
|
B3GAT3, encoding beta-1,3-glucuronyltransferase 3, has an important role in proteoglycan biosynthesis. Homozygous B3GAT3 mutations have been associated with short stature, skeletal deformities, and congenital heart defects. There is a novel B3GAT3-related disorder with craniosynostosis and bone fragility, due to a unique homozygous mutation in B3GAT3. |
|
TMPJ-01298
|
PRADC1 Protein, Human, Recombinant (His)
Protease-associated domain-containing protein of 21 kDa,Prot...
|
Human
|
HEK293 Cells
|
|
PRADC1, also known as C2orf7 or PAP21, is short for Protease-associated domain-containing protein 1. It is a 188 aa. with a 21 aa. signal, and the 171 located Asn can be glycosylated. PRADC1 has two mutagenesis which are N121Q and N171Q. This protein is secreted and highly expressed in skeletal muscle, heart and liver. It is expressed at intermediate level in kidney. |
|
TMPK-01090
|
Transthyretin/Prealbumin Protein, Cynomolgus, Recombinant (His)
Prealbumin,TBPA,CTS,HEL111,Transthyretin,TTR,ATTR,CTS1,HsT26...
|
Cynomolgus
|
HEK293 Cells
|
|
Transthyretin is a highly conserved homotetrameric protein, mainly synthetized by the liver and the choroid plexus of brain. The carrier role of TTR is well-known; however, many other functions have emerged, namely in the nervous system. TTR aggregates are responsible for many amyloidosis such as familial amyloidotic polyneuropathy and cardiomyopathy. Normal TTR can also aggregate and deposit in the heart of old people and in preeclampsia placental tissue. |
|
TMPH-02572
|
TMEM2 Protein, Mouse, Recombinant (His)
Transmembrane protein 2,Cell migration-inducing hyaluronidas...
|
Mouse
|
E. coli
|
|
Cell surface hyaluronidase that mediates the initial cleavage of extracellular high-molecular-weight hyaluronan into intermediate-size hyaluronan of approximately 5 kDa fragments. Acts as a regulator of angiogenesis and heart morphogenesis by mediating degradation of extracellular hyaluronan, thereby regulating VEGF signaling. Is very specific to hyaluronan; not able to cleave chondroitin sulfate or dermatan sulfate. |
|
TMPK-01049
|
CLEC7A Protein, Mouse, Recombinant (hFc)
CLECSF12,DC-associated C-type lectin 1,Dectin-1,Beta-glucan ...
|
Mouse
|
HEK293 Cells
|
|
Dendritic cell-associated C-type lectin-1 (Dectin-1), also known as β-glucan receptor is an emerging pattern recognition receptor (PRR) which belongs to the family of C-type lectin receptor (CLR). Dectin-1 signaling axis has been suggested to be targeted as an effective therapeutic strategy for cancers. Dectin-1 has also been elucidated ascetically in the heart, respiratory, intestinal, neurological and developmental disorders. |
|
TMPY-02961
|
PANP/C12orf53 Protein, Human, Recombinant (hFc)
C12orf53,UNQ828/PRO1755,PILR α associated neural protein,PAN...
|
Human
|
HEK293 Cells
|
|
C12orf53 is mainly expressed in adult brain and cerebellum. It also can be detected in fetal brain and virtually no expression in spleen, heart, kidney, liver and dorsal ganglion relative to brain. C12orf53 acts as a ligand for PILRA in neural tissues, where it may be involved in immune regulation. Chromosome 12 encodes over 1,100 genes within 132 million bases. A number of skeletal deformities are linked to chromosome 12 including hypochondrogenesis, achondrogenesis and Kniest dysplasia. Noonan... |
|
TMPH-03239
|
Angiopoietin-1 Protein, Rat, Recombinant (His)
ANG-1,ANGPT1,Angiopoietin-1
|
Rat
|
HEK293 Cells
|
|
Binds and activates TIE2 receptor by inducing its tyrosine phosphorylation. Implicated in endothelial developmental processes later and distinct from that of VEGF. Appears to play a crucial role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme. Mediates blood vessel maturation/stability. It may play an important role in the heart early development. Angiopoietin-1 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis ... |
|
TMPJ-01193
|
CLM-9 Protein, Human, Recombinant (aa 19-247, His)
TREM4,Triggering Receptor Expressed on Myeloid Cells 4,CD300...
|
Human
|
HEK293 Cells
|
|
CMRF35-Like Molecule 9 (CD300LG) is a single-pass type I membrane protein which belongs to the CD300 family. CD300LG has one Ig-like V-type domain which mediates binding to lymphocyte. CD300LG is highly expressed in heart, skeletal muscle and placenta. CD300LG acts as a receptor which may mediate L-selectin-dependent lymphocyte rollings. CD300LG also binds SELL in a calcium dependent manner and lymphocyte. CD300LG may play a important role in molecular traffic across the capillary endothelium. |
|
TMPJ-01062
|
HAMP Protein, Human, Recombinant (GST)
Liver-expressed antimicrobial peptide 1,HEPC,LEAP1,Putative ...
|
Human
|
E. coli
|
|
Hepcidin（HAMP）is a secreted protein that belongs to the hepcidin family.It is expressed in liver, heart and brain. It is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature peptides of 20, 22 and 25 amino acids, and these active peptides are rich in cysteines, which form intramolecular bonds that stabilize their beta sheet structure... |
|
TMPY-01771
|
Latexin Protein, Mouse, Recombinant (His)
latexin
|
Mouse
|
E. coli
|
|
Latexin, also known as endogenous carboxypeptidase inhibitor, tissue carboxypeptidase inhibitor, TCI, ECI, and LXN, is a cytoplasm protein that belongs to the protease inhibitor I47 (latexin) family. It is highly expressed in the heart, prostate, ovary, kidney, pancreas, and colon. Latexin / LXN is the only known endogenous specific inhibitor of zinc-dependent metallocarboxypeptidases (MCPs) present in mammalians so far. Latexin is originally identified as a molecular marker for the regional spe... |
|
TMPY-01099
|
GPT Protein, Rat, Recombinant (His)
Gpt1,ALAT,glutamic-pyruvate transaminase (alanine aminotrans...
|
Rat
|
Baculovirus Insect Cells
|
|
Alanine aminotransferase (ALT), also known as glutamate pyruvate transaminase (GPT), is a pyridoxal enzyme that belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family, Alanine aminotransferase subfamily. Gpt / Gpt1 / ALT catalyzes the reversible interconversion of L-alanine and 2-oxoglutalate to pyruvate and L-glutamate and plays a key role in the intermediary metabolism of glucose and amino acids. Gpt / Gpt1 / ALT is expressed in the liver, kidney, heart, and skeletal musc... |
|
TMPY-04058
|
RGS5 Protein, Human, Recombinant (His)
MST106,MSTP032,MST092,regulator of G-protein signaling 5,MST...
|
Human
|
E. coli
|
|
RGS5 is a member of the RGS superfamily and acts as a negative regulator of heterotrimeric G protein-mediated signalling through G protein-coupled receptors (GPCRs). The regulator of G-protein signaling (RGS) proteins have recently been identified as signal transduction molecules which have structural homology to SST2 of Saccharomyces cerevisiae and EGL-10 of Caenorhabditis elegans. The messenger RNA of hRGS5 was abundantly expressed in heart, lung, skeletal muscle, and small intestine, and at l... |
|
TMPJ-00963
|
CDKN2C Protein, Human, Recombinant (His)
Cyclin-Dependent Kinase 4 Inhibitor C,p18-INK4c,CDKN2C,p18-I...
|
Human
|
E. coli
|
|
Cyclin-Dependent Kinase 4 Inhibitor C (CDKN2C) is a member of the INK4 family of cyclin dependent kinase inhibitors. CDKN2C contains 4 ANK repeats and interacts with CDK4 or CDK6. Highest levels of CDKN2C can be found in skeletal muscle, pancreas, and heart. CDKN2C inhibits cell growth and proliferation with a correlated dependence on endogenous retinoblastoma protein RB and prevent the activation of the CDK kinases. Studies have been shown the roles of CDKN2C gene in regulating spermatogenesis,... |
|
TMPK-00359
|
Endoglin/CD105 Protein, Human, Recombinant (His & Avi)
CD105,ORW,ORW1,ENG,END,Endoglin,HHT1
|
Human
|
HEK293 Cells
|
|
Endoglin (CD105) is a 90 kDa type I transmembrane glycoprotein of the zona pellucida (ZP) family of proteins. Endoglin is a vascular endothelium glycoprotein that plays an important role in the regulation of angiogenesis. Required for normal structure and integrity of adult vasculature (PubMed:7894484). Regulates the migration of vascular endothelial cells. Required for normal extraembryonic angiogenesis and for embryonic heart development. May regulate endothelial cell shape changes in response... |
|
TMPJ-00687
|
B4GALT4 Protein, Human, Recombinant (His)
UDP-Gal:β-GlcNAc β-1,β4Gal-T4,4-Galactosyltransferase 4,UDP-...
|
Human
|
HEK293 Cells
|
|
β-1,4-galactosyltransferase 4 (B4GALT4) is a single-pass type II membrane protein that belongs to the Glycosyltransferase 7 family. B4GALT4 consist of the following 2 domains: N-Acetyllactosamine Synthase and β-N-Acetylglucosaminyl-Glycolipid β-1,4-Galactosyltransferase. B4GALT4 is highly expressed in the heart, placenta, kidney, and pancreas; it is lowly expressed in the brain, colon, lung, muscle, ovary, testis, and uterus. B4GALT4 function is responsible for the synthesis of complex-type N-li... |
|
TMPJ-01129
|
SMAD1 Protein, Human, Recombinant (GST)
hSMAD1,Transforming Growth Factor-Beta-Signaling Protein 1,T...
|
Human
|
E. coli
|
|
SMAD Family Member 1 (SMAD1) is a member of the dwarfin/SMAD family. SMAD1 has the highest expression in the heart and skeletal muscle, containing one MAD homology 1 domain and one MAD homology 2 domain, As a transcriptional modulator SMAD 1 is activated by bone morphogenetic proteins type 1 receptor kinase. Defects in SMAD1 may cause primary pulmonary hypertension (PPH1), characterized by plexiform lesions of proliferating endothelial cells in pulmonary arterioles. The lesions lead to elevated ... |
|
TMPJ-01388
|
STX8 Protein, Human, Recombinant
STX8,Syntaxin-8
|
Human
|
E. coli
|
|
Syntaxin-8 is a single-pass type IV membrane protein which belongs to the syntaxin family. It contains one t-SNARE coil homology domain. STX8 is highly expressed in heart, also found in brain, kidney, liver, lung, placenta, skeletal muscle, spleen and pancreas. STX8 is involved in protein trafficking from early to late endosomes via vesicle fusion and exocytosis. It as a vesicle trafficking protein functions in the early secretory pathway, possibly mediating retrograde transport form cis-golgi m... |
|
TMPJ-00242
|
PARVA Protein, Human, Recombinant (His)
PARVA,CH-ILKBP,Actopaxin,Alpha-Parvin,Matrix-Remodeling-Asso...
|
Human
|
E. coli
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Alpha-Parvin (PARVA) is a member of the Parvin family. PARVA contains two CH (calponin-homology) domains. PARVA is widely expressed, with highest levels in heart, skeletal muscle, kidney and liver. PARVA interacts with integrin-linked protein kinase and probably with actin and the LD1 and LD4 motifs of PXN. PARVA may play a role in the regulation of cell adhesion and cytoskeleton organization. PARVA is also involved in ciliogenesis. |
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TMPJ-01270
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ZMYND19 Protein, Human, Recombinant (His)
MCH-R1-Interacting Zinc Finger Protein,Zinc Finger MYND Doma...
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Human
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E. coli
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Human Zinc Finger MYND Domain-Containing Protein 19 (ZMYND19) is a protein that contains 1 MYND-Type Zinc Finger. ZMYND19 can be expressed by the brain, testis, placenta, heart, liver, skeletal muscle, kidney, and stomach. ZMYND19 interacts with GPR24/MCH-R1. It binds to the C terminus of Melanin-Concentrating Hormone Receptor-1 and the N Termini of α-Tubulin. ZMYND19 may be involved as a regulatory molecule in GPR24/MCH-R1 signaling. |
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TMPJ-00956
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MDH2 Protein, Human, Recombinant (His)
MDH2,Malate dehydrogenase,mitochondrial
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Human
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HEK293 Cells
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Malate dehydrogenase, mitochondrial is a 338 amino acids protein that belongs to the LDH/MDH superfamily. MDH type 1 family. MDH2 catalyzes the reversible oxidation of malate to oxaloacetate, utilizing the NAD/NADH cofactor system in the citric acid cycle. MDH2 is localized to the mitochondria and takes part in the malate-aspartate shuttle that functions in the metabolic coordination between cytosol and mitochondria. MDH2 is highly expressed in the adrenal system, small intestine, heart and panc... |
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TMPH-00343
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Angiopoietin-1 Protein, Canine, Recombinant (HEK293, His)
Angiopoietin-1,ANG-1,ANGPT1
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Canine
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HEK293 Cells
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Binds and activates TIE2 receptor by inducing its tyrosine phosphorylation. Implicated in endothelial developmental processes later and distinct from that of VEGF. Appears to play a crucial role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme. Mediates blood vessel maturation/stability. It may play an important role in the heart early development. Angiopoietin-1 Protein, Canine, Recombinant (HEK293, His) is expressed in HEK293 mammalian cells wi... |
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TMPJ-00650
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FIBP Protein, Human, Recombinant
FIBP,aFGF Intracellular-Binding Protein,FGF-1 Intracellular-...
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Human
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E. coli
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Acidic Fibroblast Growth Factor Intracellular-Binding Protein (FIBP) is highly expressed in the heart, skeletal muscle, and pancreas. Acidic Fibroblast Growth Factor is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FIBP is an intracellular protein that binds ... |
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