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Win-62005
还可以产品编号 T13340Cas号 152633-54-0
Win-62005 is an inhibitor of cyclic AMP phosphodiesterase III (PDE III)(Kis: 25 and 26 nM for rat heart and canine aorta).
Win-62005
还可以产品编号 T13340Cas号 152633-54-0
Win-62005 is an inhibitor of cyclic AMP phosphodiesterase III (PDE III)(Kis: 25 and 26 nM for rat heart and canine aorta).
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 25 mg | ¥ 10,600 | 6-8周 | |
| 50 mg | ¥ 13,800 | 6-8周 | |
| 100 mg | ¥ 17,500 | 6-8周 |
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化学信息
| 产品描述 | Win-62005 is an inhibitor of cyclic AMP phosphodiesterase III (PDE III)(Kis: 25 and 26 nM for rat heart and canine aorta). |
| 靶点活性 | PDE3:25 nM (ki), PDE3:ki:25 nM |
| 体外活性 | Win-62005 competitively inhibits cyclic GMP-inhibitable low Km cyclic AMP phosphodiesterase (PDE III) from rat heart and canine aorta (Ki of 25±3 and 26±5 nM, respectively )and is selective (at least 160-fold) for PDE III inhibition relative to other PDE isozymes. |
| 体内活性 | Win-62005(p.o. administration of 1 mg/kg) LVdP/dtmax is significantly increased in 30 min and remains increased for at least 6 h. |
| 分子量 | 226.23 |
| 分子式 | C12H10N4O |
| CAS No. | 152633-54-0 |
| 密度 | 1.292g/cm3 |
储存&溶解度
| 存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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请在以下方框中输入您的动物实验信息后点击计算，可以得到母液配置方法和体内配方的制备方法：
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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