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406

抑制剂 & 化合物

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天然产物

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化合物库

111

重组蛋白

13

同位素标记化合物

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Cat. No.	Product Name
L2190	抗肺癌化合物库		1702 compounds
	1702 种与肺癌相关的化合物，可以用于抗肺癌药物研发和药理研究；
L4520	抗菌活性库		904 compounds
	904 种具有抗菌活性的化合物，是抗菌药物研发的有力工具；
L4510	抗寄生虫库		419 compounds
	419 种具有抗寄生虫活性的小分子化合物；
L9410	共价抑制剂库		1920 compounds
	1920 种小分子的独特集合，包含已发现的共价抑制剂以及包含某些共价反应基团常见弹头的分子，如氯乙酰基，2-氯丙酰基，丙烯酰基，1-丙-2-炔基，1-丁-2-炔基，酮羰基，二硫键等，可以用于共价抑制剂药物研发；
L3900	DNA 损伤和修复分子库		910 compounds
	910 个与 DNA 损伤和修复紧密相关的化合物集合，是高通量筛选，高内涵筛选的良好载体；
L4400	抗生素库		692 compounds
	692 个具有抗菌活性化合物的独特集合，是医药研究的优良工具库和药物筛选的有效载体；
L3980	DNA损伤/修复库Plus		667 compounds
	667 种 DNA 损伤/修复靶向、结构新颖的化合物；
L7110	抗高血压化合物库		678 compounds
	678 种高血压相关的小分子，用于高通量和高内涵筛选；
L9300	大环化合物库		210 compounds
	210 种活性已知的大环化合物，用于高通量、高内涵筛选；
L2140	癌细胞分化化合物库		406 compounds
	406 个诱导肿瘤细胞分化化合物的独特集合，可用于高通量筛选和高内涵筛选；
L2130	抗癌细胞代谢库		1268 compounds
	1268 种癌细胞代谢相关的生物活性小分子化合物的特有集合，用于肿瘤相关的研究以及抗肿瘤药物的筛选，用于高通量、高内涵筛选；
L9240	农药化合物库		270 compounds
	270种农药相关化合物的独特集合，可用于高通量筛选和高内涵筛选；
L6730	抗病毒中药单体化合物库		268 compounds
	268 种具有抗病毒活性的中药单体集合，是药物开发、药理研究的有效工具；
L2540	肠道微生物代谢化合物库		614 compounds
	614 种肠道微生物代谢物的集合，可以用于高通量和高内涵筛选；
L9700	内质网应激化合物库		193 compounds
	193 个内质网应激相关的化合物集合，可用于高通量和高内涵筛选；
L6610	抗感染天然产物库		1060 compounds
	1060 个抗感染相关的天然产物集合，是药物开发、药理研究的有效工具；
DO2200	共价抑制剂库CD		12000 compounds
	数量多：超过12000种共价结合化合物，并且数量在持续增加；

化合物库

抗肺癌化合物库

Cat.No: L2190

Compounds: 1702

抗菌活性库

Cat.No: L4520

Compounds: 904

抗寄生虫库

Cat.No: L4510

Compounds: 419

共价抑制剂库

Cat.No: L9410

Compounds: 1920

DNA 损伤和修复分子库

Cat.No: L3900

Compounds: 910

Cat.No: L4400

Compounds: 692

DNA损伤/修复库Plus

Cat.No: L3980

Compounds: 667

抗高血压化合物库

Cat.No: L7110

Compounds: 678

大环化合物库

Cat.No: L9300

Compounds: 210

癌细胞分化化合物库

Cat.No: L2140

Compounds: 406

抗癌细胞代谢库

Cat.No: L2130

Compounds: 1268

农药化合物库

Cat.No: L9240

Compounds: 270

抗病毒中药单体化合物库

Cat.No: L6730

Compounds: 268

肠道微生物代谢化合物库

Cat.No: L2540

Compounds: 614

内质网应激化合物库

Cat.No: L9700

Compounds: 193

抗感染天然产物库

Cat.No: L6610

Compounds: 1060

共价抑制剂库CD

Cat.No: DO2200

Compounds: 12000

Cat. No.	Product Name	Target	Signaling Pathways
T83892	33-BCRP Inhibitor 33-Breast Cancer Resistance Protein Inhibitor	Others	Others
	33-BCRP抑制剂是一种乳腺癌耐药蛋白(BCRP)的抑制剂。它使得对米托蒽醌耐药的H460/MX20肺癌细胞对米托蒽醌诱导的细胞死亡更加敏感，无论是单独使用还是与UV辐射联合使用。33-BCRP抑制剂还能够增强表达P-糖蛋白(P-gp，亦称为多药耐药蛋白MDR)的KB-C2表皮癌细胞对秋水仙碱诱导的细胞死亡的敏感性。当使用5 µM浓度时，它能增加米托蒽醌在H460/MX20细胞中的细胞内积累。
T21876	DC_AC50	Apoptosis; Others	Apoptosis; Others
	DC_AC50 是一种 Atox 和 CCS 的双抑制剂，是一种抑制细胞内铜伴侣作为减少/预防获得性化疗耐药性的手段。它与 Atox1 和 CCS 结合并减少癌细胞增殖和肿瘤生长。
T9982	PU23	MRP	Immunology/Inflammation
	PU 23 是一种多药抗性蛋白4(MRP4)的抑制剂。
T4595	YHO-13177 YHO 13177,YHO13177	BCRP	Membrane transporter/Ion channel
	YHO-13177 是高活性乳腺癌耐药蛋白多药转运通道（BCRP）抑制剂，可增强SN-38活性。
TQ0186	Ko 143	BCRP; ABC	Membrane transporter/Ion channel
	Ko 143 有效且选择性抑制 ATP 结合盒亚家族 G 成员 2 (ABCG2/BCRP)
T3581	KS176	Potassium Channel; BCRP	Membrane transporter/Ion channel
	KS176是选择性高活性乳腺癌耐药蛋白多药转运通道抑制剂，在Pheo A 和Hoechst 检测中，IC50值分别为0.59和1.39 μM。
T13383	Zamicastat BIA 5-1058	BCRP; Hydroxylase; P-gp	Membrane transporter/Ion channel; Metabolism; Neuroscience
	Zamicastat (BIA 5-1058) 是多巴胺 β-羟化酶 (DBH) 抑制剂，可透过血脑屏障引起中枢和周边效应，具有降血压作用。它也是一种浓度依赖性的双重 P-gp 和 BCRP 抑制剂，IC50值分别为 73.8 和 17.0 μM。
T38400	Triclabendazole sulfoxide TCBZ-SO,三氯苯达唑亚砜	BCRP; Parasite	Membrane transporter/Ion channel; Microbiology/Virology
	Triclabendazole sulfoxide (TCBZ-SO) 是 Triclabendazole 的主要血浆代谢产物。Triclabendazole sulfoxide 具有抗寄生虫活性。Triclabendazole sulfoxide 可以抑制膜转运蛋白ABCG2/BCRP 的活性。
T1248	Sulfanitran 磺胺硝苯,乙酰磺胺对硝基苯	Antibacterial; Autophagy	Autophagy; Microbiology/Virology
	Sulfanitran 是一种用于家禽业的磺胺类抗生素。它也是一种多药耐药蛋白 2 (MRP2) 激动剂，可增加 MRP2 对雌二醇 17-β-D-葡糖醛酸的亲和力。
T3971	CASIN Pirl1-related Compound 2	CDK; STAT; Ras	Cell Cycle/Checkpoint; GPCR/G Protein; JAK/STAT signaling; MAPK; Stem Cells
	CASIN (Pirl1-related Compound 2) 是选择性GTPase Cdc42抑制剂，IC50值是 2 uM。
T21955	GQ-16	PPAR	DNA Damage/DNA Repair; Metabolism
	GQ-16 是 PPARγ 的部分激动剂，Ki 为 160 nM。 GQ-16 可减少脂肪生成作用并促进胰岛素敏化而不会增加体重。
T27617	Inz-1	P450	Metabolism
	Inz-1 是一种有效的真菌特异性线粒体细胞色素 bc1 抑制剂，对酵母和人类的 IC50 分别为 8.092 和 45.320 μM。 Inz-1 可逆转氟康唑或其他三唑类抗真菌药对致病性真菌白色念珠菌的耐药性。
T2680	NVP-BVU972	c-Met/HGFR	Tyrosine Kinase/Adaptors
	NVP-BVU972 是 Met 选择性抑制剂 (IC50:14 nM) ，它对其它的激酶抑制性较低。
T8157	Centhaquin PMZ-2010,Centhaquine	Others	Others
	Centhaquin (Centhaquine)e 是一种具有研究出血性休克的潜力的试剂。在出血模型中，它能够减少全身血管阻力。
T4628	Seladelpar MBX 8025	PPAR	DNA Damage/DNA Repair; Metabolism
	Seladelpar (MBX 8025) 是一种有效的，具有口服活性的，特异性PPAR-δ激动剂，EC50为 2 nM。
T12832	Amcenestrant SAR439859	Estrogen Receptor/ERR; Estrogen/progestogen Receptor	Endocrinology/Hormones
	Amcenestrant (SAR439859) 是一种有效的 ER 拮抗剂，具有 ER 降解活性，EC50为 0.2 nM。它是一种具有口服活性，非甾体和选择性雌激素受体降解剂 (SERD)。它可在 ER+乳腺癌中表现出强大的抗肿瘤功效和有限的交叉耐药性。
T16561	Polyoxyethylene stearate POES,聚氧乙烯硬脂酸酯	Antibacterial; P-gp	Membrane transporter/Ion channel; Microbiology/Virology; Neuroscience
	Polyoxyethylene stearate (POES) 是一种非离子乳化剂。
T7656	Apelin-13
	Apelin-13 是存在于中枢和外周神经系统由13个氨基酸组成的多肽序列，是 G 蛋白偶联受体angiotensin II protein J (APJ) 的内源性配体，对 APJ 的 EC50 值为 0.37 nM。Apelin-13 具有扩张血管和降压活性，可用于研究 2 型糖尿病综合征。
T8596	Ceefourin 1	MRP	Immunology/Inflammation
	Ceefourin 1 是一种具有高度选择性的多药抗性蛋白 4 (MRP4) 抑制剂。它能够抑制多种 MRP4 底物的转运，但对其他 ABC 转运蛋白无影响。它是苯并噻唑，常作为高危神经母细胞瘤的化学增敏剂。
T4337	PCI 29732 PCI29732,PCI-29732	Others; BCRP; BTK	Angiogenesis; Membrane transporter/Ion channel; Others; Tyrosine Kinase/Adaptors
	PCI 29732 是一种有效的可逆BTK 抑制剂，对 BTK、Lck 和 Lyn 的Kiapp 值分别为 8.2、4.6 和 2.5 nM。它通过竞争性结合ABCG2 的 ATP 结合位点来抑制ABCG2的功能。
T22459	Xanthinol Nicotinate Angioamin,烟酸占替诺,Complamin	Others	Others
	Xanthinol Nicotinate (Complamin) 是血管扩张剂，可直接作用于小动脉和毛细血管的平滑肌，能够扩大血管，改善血液流变学并降低外周血管阻力。
T12341	P-gp inhibitor 1	Others; P-gp	Membrane transporter/Ion channel; Neuroscience; Others
	P-gp inhibitor 1 抑制逆转 P-糖蛋白介导的多药耐药性，EC50 为 57.9 nM（K562/A02 细胞）。
T2620	G-749 G749	Apoptosis; FLT; c-RET; TAM Receptor; Aurora Kinase	Angiogenesis; Apoptosis; Cell Cycle/Checkpoint; Chromatin/Epigenetic; Tyrosine Kinase/Adaptors
	G-749 是一种新型 FLT3 抑制剂，对 FLT3 野生型和突变体有持续的抑制作用，IC50值分别为 0.4 nM 和 0.6 nM。它可用于急性髓系白血病的耐药研究。
T8426	Encequidar HM30181,HM30181A	P-gp	Membrane transporter/Ion channel; Neuroscience
	Encequidar (HM30181A) 是一种选择性 P-糖蛋白抑制剂。
T11071	Dofequidar fumarate MS-209	P-gp	Membrane transporter/Ion channel; Neuroscience
	Dofequidar fumarate (MS-209) 是口服活性的喹啉化合物，通过抑制 ABCB1/P-gp 和 ABCC1/MDR 相关蛋白 1 来克服 MDR。
T2657	Elacridar GW0918,依克立达,GW120918,GF120918,GG918	BCRP; P-gp	Membrane transporter/Ion channel; Neuroscience
	Elacridar (GG918) 是一种有效的 P-糖蛋白和BCRP 的抑制剂。
T0351	Risperidone Risperidal,R 64 766,利培酮	Dopamine Receptor; 5-HT Receptor; Adrenergic Receptor; P-gp	GPCR/G Protein; Membrane transporter/Ion channel; Neuroscience
	Risperidone (R 64 766) 是5-HT2受体阻断剂、P-糖蛋白抑制剂和多巴胺 D2受体的拮抗剂，对 5-HT2A 和多巴胺 D2受体的 Ki 值分别为 4.8 和 5.9 nM。
T6287	Tariquidar XR9576,他立喹达	P-gp	Membrane transporter/Ion channel; Neuroscience
	Tariquidar (XR9576) 是一种特异性有效的P-糖蛋白抑制剂，Kd 为 5.1 nM。
T3071	Olverembatinib GZD 824	Bcr-Abl	Angiogenesis; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors
	Olverembatinib (GZD 824) 是一种高效的、口服具有活性的pan-Bcr-Abl 抑制剂，具有抗肿瘤活性。它能广泛而有效地抑制突变型 Bcr-Abl。它对天然的 Bcr-Abl 和 Bcr-AblT315I 作用的IC50值分别为 0.34 nM 和 0.68 nM。
T8389	Trifluoperazine 三氟拉嗪,trifluoroperazine	CaMK; Dopamine Receptor; Influenza Virus; Adrenergic Receptor; P-gp; Autophagy	Autophagy; GPCR/G Protein; Membrane transporter/Ion channel; Microbiology/Virology; Neuroscience
	Trifluoperazine (trifluoroperazine) 是一种多巴胺 D2 受体抑制剂，可治疗精神分裂症。它是NUPR1抑制剂，具有抗癌活性。它是α1-adrenergic 受体拮抗剂，是流感病毒形态发生的可逆抑制剂。
T4059	Selamectin UK-124114,司拉克丁,塞拉菌素	Chloride channel; P-gp; Parasite	Membrane transporter/Ion channel; Microbiology/Virology; Neuroscience
	Selamectin (UK-124114) 是半合成的大环内酯，是一种驱虫剂，可增强线虫中谷氨酸和 GABA 门控氯离子通道的开放。它还是抗寄生虫剂，可激活神经元和咽肌中的谷氨酸门控氯离子通道，以预防恶丝虫，淋巴丝虫和线虫感染。它还是 P-糖蛋白底物和抑制剂，IC50为 120 nM。
T9179	CLP-3094 2-([2-(4-CHLOROPHENOXY)ETHYL]THIO)-1H-BE	Androgen Receptor	Endocrinology/Hormones
	CLP-3094 (2-([2-(4-CHLOROPHENOXY)ETHYL]THIO)-1H-BE) 是一种雄激素受体 BF3(binding function 3) 抑制剂，是一种选择性GPR142拮抗剂。BF3-IN-1 抑制 AR 转录活性 (IC50:4 μM)。
T7714	Temocapil	Tyrosinase	Proteases/Proteasome
	Temocapil 是一种酪氨酸激酶抑制剂。
T1634	Glibenclamide 格列本脲,Glyburide	Potassium Channel; Mitochondrial Metabolism; CFTR; P-gp; Autophagy	Autophagy; Membrane transporter/Ion channel; Metabolism; Neuroscience
	Glibenclamide (Glyburide) 是一种具有口服活性的 ATP 敏感的 K+通道抑制剂，可研究糖尿病和肥胖。它抑制 P-糖蛋白，可直接结合并阻断 KATP 的 SUR1亚基并抑制囊性纤维化跨膜传导调节蛋白。它通过诱导膜离子通透性干扰线粒体生物能，可诱导自噬。
T2429	Olverembatinib dimesylate GZD824 Dimesylate,HQP1351	Bcr-Abl	Angiogenesis; Cytoskeletal Signaling; Tyrosine Kinase/Adaptors
	Olverembatinib dimesylate (GZD824 Dimesylate) 是一种高效的、口服具有活性的pan-Bcr-Abl 抑制剂，具有抗肿瘤活性。它能广泛而有效地抑制突变型 Bcr-Abl。它对天然的 Bcr-Abl 和 Bcr-AblT315I 作用的IC50值分别为 0.34 nM 和 0.68 nM。
T1275	Phentolamine mesylate Phentolamine methanesulfonate,甲磺酸酚妥拉明,Phentolamine mesilate	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Phentolamine mesylate (Phentolamine methanesulfonate) 是一种非选择性的、可逆的，具有口服活性的 α1 和 α2 肾上腺素能受体阻滞剂，能够扩张使血管，降低周围血管阻力。它可用于研究嗜铬细胞瘤相关的高血压，心力衰竭和勃起功能障碍。
T13416	ZX-29	ALK	Angiogenesis; Tyrosine Kinase/Adaptors
	ZX-29 是一种选择性ALK 抑制剂，对ALK、ALK L1196M 和ALK G1202R 的IC50分别为 2.1 nM、1.3 nM 和 3.9 nM。它还可诱导保护性自噬并具有抗肿瘤作用。它通过诱导内质网应激来诱导细胞凋亡，并克服了由ALK 突变引起的细胞抗性。
T15735	Leptomycin B CI 940,LMB,来普霉素B	CRM1; Antibiotic; Antifungal	Membrane transporter/Ion channel; Microbiology/Virology
	Leptomycin B (LMB) 是一种抗真菌抗生素，可阻断真核细胞周期，抑制蛋白出核转运。Leptomycin 通过半胱氨酸残基处的共价修饰使 CRM1/exportin 1失活。它
T11578L	Encequidar mesylate HM30181 mesylate,HM30181A mesylate	P-gp	Membrane transporter/Ion channel; Neuroscience
	Encequidar mesylate (HM30181A mesylate) 是竞争性有效的 P-糖蛋白抑制剂。
T0100L	Atazanavir Zrivada,Reyataz,Latazanavir,阿扎那韦,BMS-232632	P450; SARS-CoV; HIV Protease; P-gp	Membrane transporter/Ion channel; Metabolism; Microbiology/Virology; Neuroscience; Proteases/Proteasome
	Atazanavir (BMS-232632) 是一种高选择性的HIV-1蛋白酶抑制剂，可研究艾滋病毒感染。它也是SARS-CoV 3CLpro 的抑制剂，IC50为 3.49 μM。它是CYP3A4的底物和抑制剂，也是P-糖蛋白的抑制剂和诱导剂。
T16028	IMB-XH1 Mcl1-IN-2,7-[(2-吡啶基氨基)-2-噻吩基甲基]-8-喹啉醇	BCL; Antibacterial	Apoptosis; Microbiology/Virology
	IMB-XH1 (Mcl1-IN-2) 是一种骨髓细胞因子 1 抑制剂。它也是非竞争性的 Delhi metallo-β-lactamase(NDM-1) 抑制剂。它对金属 β-内酰胺酶 NDM-1，IMP-4，ImiS 和 L1 的 IC50值分别为 0.4637 μM，3.980 μM，0.2287 μM 和 1.158 μM。
T10353	APX-115 free base Ewha-18278 free base	NADPH-oxidase; NADPH	Immunology/Inflammation; Metabolism
	APX-115 free base (Ewha-18278 free base) 是口服具有活性的、非选择性的 Nox 抑制剂，对 Nox1，Nox2和 Nox4的 Ki 分别为 1.08 μM，0.57 μM 和 0.63 μM。它能够有效预防糖尿病小鼠的肾损伤。
T14364	AZ-Dyrk1B-33 3-(2-Methyl-4-pyrimidinyl)-1-(phenylmethyl)-1H-pyrrolo[2,3-c]pyridine	DYRK	Cell Cycle/Checkpoint; Tyrosine Kinase/Adaptors
	AZ-Dyrk1B-33 (3-(2-Methyl-4-pyrimidinyl)-1-(phenylmethyl)-1H-pyrrolo[2,3-c]pyridine) 是高选择性的Dyrk1B 激酶抑制剂，其IC50=7 nM。
T2330	Rilpivirine TMC278,R278474,利匹韦林,DB08864	HIV Protease; Reverse Transcriptase	Microbiology/Virology; Proteases/Proteasome
	Rilpivirine (R278474) 是一种二芳基嘧啶衍生物和非核苷逆转录酶抑制剂，具有抗 HIV-1 的抗病毒活性，用于治疗 HIV 感染。
T16339	Norverapamil hydrochloride (±)-Norverapamil hydrochloride,D591 hydrochloride,盐酸去甲维拉帕米	Calcium Channel; P-gp; Drug Metabolite	Membrane transporter/Ion channel; Metabolism; Neuroscience
	Norverapamil hydrochloride (D591 hydrochloride) 是 Verapamil 的 N-去甲基代谢物，是 L 型钙通道阻滞剂和 P-糖蛋白 (P-gp) 功能抑制剂。
T1967	AZD-3463 ALK/IGF1R inhibitor	Apoptosis; IGF-1R; ALK; Autophagy	Angiogenesis; Apoptosis; Autophagy; Tyrosine Kinase/Adaptors
	AZD-3463 (ALK/IGF1R inhibitor) 是一种具有口服活性的ALK/IGF1R 抑制剂，对 ALK 作用的Ki 值为 0.75 nM。它可诱导神经母细胞瘤细胞凋亡和自噬。
T1010	Verapamil hydrochloride Manidon,盐酸维拉帕米,(±)-Verapamil hydrochlorid,Verapamil HCl,Calcan hydrochloride	P450; Calcium Channel; P-gp	Membrane transporter/Ion channel; Metabolism; Neuroscience
	Verapamil hydrochloride (Verapamil HCl) 是一种钙通道阻滞剂，是一种可口服的 P 糖蛋白 (P-gp) 抑制剂，可抑制CYP3A4，用于高血压、心律不齐和心绞痛的研究。
T20656	Verapamil NSC 135784,维拉帕米,NSC-135784,CP-16533-1,(±)-Verapamil	P450; Calcium Channel; P-gp	Membrane transporter/Ion channel; Metabolism; Neuroscience
	Verapamil (CP-16533-1) 是一种非二氢吡啶类钙通道阻滞剂，一种 P-gp 抑制剂，也是一种 CYP3A4 抑制剂，具有口服活性。Verapamil 可以用于治疗高血压、心绞痛、心肌梗塞等。
T1222	Trifluoperazine dihydrochloride Trifluoperazine 2HCl,盐酸三氟拉嗪,SKF5019,Urinox	CaMK; Dopamine Receptor; Influenza Virus; Adrenergic Receptor; P-gp; Autophagy	Autophagy; GPCR/G Protein; Membrane transporter/Ion channel; Microbiology/Virology; Neuroscience
	Trifluoperazine dihydrochloride (SKF5019) 是一种抗精神病药物，靶向中枢多巴胺受体。它是流感病毒形态发生的可逆抑制剂，是NUPR1抑制剂，具有抗癌活性。它是钙调蛋白抑制剂，还可抑制 P-糖蛋白，可研究精神分裂症。
T0100	Atazanavir sulfate 阿扎那韦硫酸盐,BMS-232632,BMS-232632 sulfate,硫酸阿扎那韦	P450; SARS-CoV; HIV Protease; P-gp	Membrane transporter/Ion channel; Metabolism; Microbiology/Virology; Neuroscience; Proteases/Proteasome
	Atazanavir sulfate (BMS-232632 sulfate) 是一种氮杂肽和 HIV 蛋白酶抑制剂，与其他抗 HIV 药物联合用于治疗 HIV 感染和艾滋病。它也是SARS-CoV 3CLpro 抑制剂，IC50为 3.49 μM。

化合物

33-BCRP Inhibitor

Cat.No: T83892

Synonym: 33-Breast Cancer Resistance Protein Inhibitor

Target: Others

Cat.No: T21876

Target: Apoptosis, Others

Cat.No: T9982

Target: MRP

Cat.No: T4595

Synonym: YHO 13177,YHO13177

Target: BCRP

Cat.No: TQ0186

Target: BCRP, ABC

Cat.No: T3581

Target: Potassium Channel, BCRP

Cat.No: T13383

Synonym: BIA 5-1058

Target: BCRP, Hydroxylase, P-gp

Triclabendazole sulfoxide

Cat.No: T38400

Synonym: TCBZ-SO,三氯苯达唑亚砜

Target: BCRP, Parasite

Cat.No: T1248

Synonym: 磺胺硝苯,乙酰磺胺对硝基苯

Target: Antibacterial, Autophagy

Cat.No: T3971

Synonym: Pirl1-related Compound 2

Target: CDK, STAT, Ras

Cat.No: T21955

Target: PPAR

Cat.No: T27617

Target: P450

Cat.No: T2680

Target: c-Met/HGFR

Cat.No: T8157

Synonym: PMZ-2010,Centhaquine

Target: Others

Cat.No: T4628

Synonym: MBX 8025

Target: PPAR

Cat.No: T12832

Synonym: SAR439859

Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor

Polyoxyethylene stearate

Cat.No: T16561

Synonym: POES,聚氧乙烯硬脂酸酯

Target: Antibacterial, P-gp

Cat.No: T7656

Cat.No: T8596

Target: MRP

Cat.No: T4337

Synonym: PCI29732,PCI-29732

Target: Others, BCRP, BTK

Xanthinol Nicotinate

Cat.No: T22459

Synonym: Angioamin,烟酸占替诺,Complamin

Target: Others

P-gp inhibitor 1

Cat.No: T12341

Target: Others, P-gp

Cat.No: T2620

Synonym: G749

Target: Apoptosis, FLT, c-RET, TAM Receptor, Aurora Kinase

Cat.No: T8426

Synonym: HM30181,HM30181A

Target: P-gp

Dofequidar fumarate

Cat.No: T11071

Synonym: MS-209

Target: P-gp

Cat.No: T2657

Synonym: GW0918,依克立达,GW120918,GF120918,GG918

Target: BCRP, P-gp

Cat.No: T0351

Synonym: Risperidal,R 64 766,利培酮

Target: Dopamine Receptor, 5-HT Receptor, Adrenergic Receptor, P-gp

Cat.No: T6287

Synonym: XR9576,他立喹达

Target: P-gp

Cat.No: T3071

Synonym: GZD 824

Target: Bcr-Abl

Trifluoperazine

Cat.No: T8389

Synonym: 三氟拉嗪,trifluoroperazine

Target: CaMK, Dopamine Receptor, Influenza Virus, Adrenergic Receptor, P-gp, Autophagy

Cat.No: T4059

Synonym: UK-124114,司拉克丁,塞拉菌素

Target: Chloride channel, P-gp, Parasite

Cat.No: T9179

Synonym: 2-([2-(4-CHLOROPHENOXY)ETHYL]THIO)-1H-BE

Target: Androgen Receptor

Cat.No: T7714

Target: Tyrosinase

Cat.No: T1634

Synonym: 格列本脲,Glyburide

Target: Potassium Channel, Mitochondrial Metabolism, CFTR, P-gp, Autophagy

Olverembatinib dimesylate

Cat.No: T2429

Synonym: GZD824 Dimesylate,HQP1351

Target: Bcr-Abl

Phentolamine mesylate

Cat.No: T1275

Synonym: Phentolamine methanesulfonate,甲磺酸酚妥拉明,Phentolamine mesilate

Target: Adrenergic Receptor

Cat.No: T13416

Target: ALK

Cat.No: T15735

Synonym: CI 940,LMB,来普霉素B

Target: CRM1, Antibiotic, Antifungal

Encequidar mesylate

Cat.No: T11578L

Synonym: HM30181 mesylate,HM30181A mesylate

Target: P-gp

Cat.No: T0100L

Synonym: Zrivada,Reyataz,Latazanavir,阿扎那韦,BMS-232632

Target: P450, SARS-CoV, HIV Protease, P-gp

Cat.No: T16028

Synonym: Mcl1-IN-2,7-[(2-吡啶基氨基)-2-噻吩基甲基]-8-喹啉醇

Target: BCL, Antibacterial

APX-115 free base

Cat.No: T10353

Synonym: Ewha-18278 free base

Target: NADPH-oxidase, NADPH

Cat.No: T14364

Synonym: 3-(2-Methyl-4-pyrimidinyl)-1-(phenylmethyl)-1H-pyrrolo[2,3-c]pyridine

Target: DYRK

Cat.No: T2330

Synonym: TMC278,R278474,利匹韦林,DB08864

Target: HIV Protease, Reverse Transcriptase

Norverapamil hydrochloride

Cat.No: T16339

Synonym: (±)-Norverapamil hydrochloride,D591 hydrochloride,盐酸去甲维拉帕米

Target: Calcium Channel, P-gp, Drug Metabolite

Cat.No: T1967

Synonym: ALK/IGF1R inhibitor

Target: Apoptosis, IGF-1R, ALK, Autophagy

Verapamil hydrochloride

Cat.No: T1010

Synonym: Manidon,盐酸维拉帕米,(±)-Verapamil hydrochlorid,Verapamil HCl,Calcan hydrochloride

Target: P450, Calcium Channel, P-gp

Cat.No: T20656

Synonym: NSC 135784,维拉帕米,NSC-135784,CP-16533-1,(±)-Verapamil

Target: P450, Calcium Channel, P-gp

Trifluoperazine dihydrochloride

Cat.No: T1222

Synonym: Trifluoperazine 2HCl,盐酸三氟拉嗪,SKF5019,Urinox

Target: CaMK, Dopamine Receptor, Influenza Virus, Adrenergic Receptor, P-gp, Autophagy

Atazanavir sulfate

Cat.No: T0100

Synonym: 阿扎那韦硫酸盐,BMS-232632,BMS-232632 sulfate,硫酸阿扎那韦

Target: P450, SARS-CoV, HIV Protease, P-gp

Cat. No.	Product Name	Target	Signaling Pathways
T3881	Vaccarin	Integrin; Akt; PERK; AMPK	Apoptosis; Chromatin/Epigenetic; Cytoskeletal Signaling; PI3K/Akt/mTOR signaling
	Vaccarin 是从王不留行中提取的一种黄酮糖苷，可显著促进伤口愈合以及伤口部位的内皮和成纤维细胞增殖。它通过激活 AMPK 信号通路改善胰岛素抵抗和脂肪变性。
T10815	Cinnamoylglycine	Endogenous Metabolite	Metabolism
	Cinnamoylglycine 是肉桂酸和的甘氨酸结合物，是人体尿液代谢物。它被用作的尿液标志物，能够作为在抗生素研究期之后定殖耐药性的标志物。
TN1651	Furanodiene	Apoptosis; PARP; Reactive Oxygen Species; Caspase; CDK; P-gp	Apoptosis; Cell Cycle/Checkpoint; Chromatin/Epigenetic; DNA Damage/DNA Repair; Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism; Neuroscience; NF-κB; Proteases/Proteasome
	Furanodiene 是从姜黄中提取的一种萜类天然产物，可抑制外排转运蛋白Pgp 功能并降低 Pgp 蛋白水平。它通过抗血管生成和诱导ROS 产生，DNA 链断裂和细胞凋亡发挥抗癌作用。
T3S0012	coniferyl ferulate	P-gp; GST	Membrane transporter/Ion channel; Neuroscience; oxidation-reduction
	Coniferyl ferulate 是从川芎中提取的一种天然产物，是强效的谷胱甘肽 S-转移酶抑制剂，强抑制人胎盘型谷胱甘肽 S-转移酶，IC50为 0.3 μM。它还可逆转多药耐药性并下调 P-糖蛋白。
T6670	Silymarin Silybin B,水飞蓟素	SARS-CoV	Microbiology/Virology
	Silymarin (Silybin B) 是一种多酚类黄酮，是从水飞蓟或水飞蓟的种子中提取的一种 SARS-CoV-2 主蛋白酶抑制剂。它可降低肿瘤细胞的增殖，血管生成以及胰岛素抵抗，用于预防和治疗肝脏疾病，有潜力研究 COVID-19 。
TN4761	Phellamurin	P-gp	Membrane transporter/Ion channel; Neuroscience
	Phellamurin 是一种来自黄檗叶的黄酮糖苷，可诱导细胞凋亡，具有抗肿瘤活性。它抑制肠道 P-糖蛋白，还抑制凤蝶的产卵。
T2S0223	Isosinensetin 异橙黄酮,6-Demethoxynobiletin	Antioxidant; HIV Protease; Antibacterial; P-gp	Membrane transporter/Ion channel; Microbiology/Virology; Neuroscience; oxidation-reduction; Proteases/Proteasome
	Isosinensetin (6-Demethoxynobiletin) 是从青皮中提取的一种甲氧基黄酮，具有抗氧化和抑制 HIV-1 蛋白酶的活性。
T2S0271	Voacamine 老刺木胺,Voacanginine	Cannabinoid Receptor; P-gp	GPCR/G Protein; Membrane transporter/Ion channel; Neuroscience
	Voacamine (Voacanginine) 是非洲马铃果中的一种吲哚生物碱，可抑制多药耐药肿瘤细胞中的 P-糖蛋白作用，具有强效的大麻素 CB1受体拮抗活性。
T3002	Piperine 胡椒碱,1-Piperoylpiperidine,Bioperine	P450; Endogenous Metabolite; P-gp; Autophagy	Autophagy; Membrane transporter/Ion channel; Metabolism; Neuroscience
	Piperine (Bioperine) 是从胡椒中分离的一种生物碱，可以抑制P-糖蛋白和 CYP3A4 的活性，在HeLa 细胞中的IC50值为61.94±0.054 μg/mL。它已用于研究治疗多发性骨髓瘤和吞咽障碍的试验。
T2869	Emodin Frangula emodin,大黄素	SARS-CoV; Casein Kinase; Autophagy	Autophagy; Metabolism; Microbiology/Virology; Stem Cells
	Emodin (Frangula emodin) 是蒽醌衍生物，有抗SARS-CoV 作用。它阻断 SARS 冠状病毒刺突蛋白和血管紧张素转化酶 2 的相互作用。它抑制酪蛋白激酶 2 ，具有抗炎和抗癌作用。它可改善饮食诱导的肥胖小鼠的代谢紊乱。
T3392	Sinapine thiocyanate	P-gp; AChE	Membrane transporter/Ion channel; Neuroscience
	Sinapine thiocyanate 是萝卜中分离出来的一种生物碱，具有抗炎、抗氧化、抗肿瘤、抗血管生成和放射防护作用。它还是乙酰胆碱酯酶抑制剂，可用于研究阿尔茨海默症，共济失调，重症肌无力和帕金森氏病。
TJS1159	Chrysosplenetin 猫眼草黄素,Chrysosptertin B	P450; Ferroptosis; P-gp	Apoptosis; Membrane transporter/Ion channel; Metabolism; Neuroscience
	Chrysosplenetin 是青蒿和其他几种中草药中的一种多甲氧基化黄酮类天然产物，抑制 P-gp 活性并逆转由青蒿素诱导的上调的 P-gp 和 MDR1 水平。
T2S1200	Sinapine	Antioxidant; P-gp; AChE	Membrane transporter/Ion channel; Neuroscience; oxidation-reduction
	Sinapine 是萝卜中分离出来的一种生物碱，具有抗炎、抗氧化、抗肿瘤、抗血管生成和放射防护作用。它还是乙酰胆碱酯酶抑制剂，可用于研究阿尔茨海默症，共济失调，重症肌无力和帕金森氏病。
TL0006	Cichoric Acid 菊苣酸,Dicaffeoyltartaric acid,Chicoric Acid	Reactive Oxygen Species; HIV Protease	Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB; Proteases/Proteasome
	Cichoric Acid (Dicaffeoyltartaric acid) 是一种天然化合物，具有抗氧化作用。
T19458	N-Hydroxypipecolic acid 1-Hydroxy-2-piperidinecarboxylic acid,NHP	Others	Others
	N-Hydroxypipecolic acid (NHP) 是植物代谢产物和系统性获得性抗性调节剂，可与免疫信号水杨酸协调建立系统性获得性抗性，诱导系统获得性耐药对细菌和卵菌感染。它在植物叶片中系统地积累，以应对病原菌的侵袭。
TN6339	(R)-5-Hydroxy-1,7-diphenylheptan-3-one (5R)-Dihydroyashabushiketol,(R)-5-羟基-1,7-二苯基-3-庚酮	Others	Others
	(R)-5-Hydroxy-1,7-diphenylheptan-3-one ((5R)-Dihydroyashabushiketol) 是从中药材高良姜的根茎中提取的。它抑制茶碱刺激的鼠 B16 黑色素瘤 4A5 细胞中的黑色素生成。
T4034	Solamargine Solamargin,δ-Solanigrine,澳洲茄边碱	Apoptosis; p38 MAPK; P-gp; STAT	Apoptosis; JAK/STAT signaling; MAPK; Membrane transporter/Ion channel; Neuroscience; Stem Cells
	Solamargine (δ-Solanigrine) 是一种来源于茄属植物的类固醇 Solasodine 的衍生物，诱导非选择性细胞毒性和 P-gp 抑制作用。它通过下调 MMP-2 和 MMP-9 的表达和活性来显著抑制 HepG2 细胞的迁移和侵袭，在多种癌症中均表现出抗癌活性。
TN1757	Hypophyllanthin 叶下珠次素,(7S,8S,9R)-9-(3,4-二甲氧基苯基)-6,7,8,9-四氢-4-甲氧基-7,8-双(甲氧基甲基)萘并[1,2-D]-1,3-二恶茂	Potassium Channel; Calcium Channel; P-gp	Membrane transporter/Ion channel; Metabolism; Neuroscience
	Hypophyllanthin 是珠子草中的一种木脂素，能直接抑制 P-gp 的活性，具有很强的抗炎活性。
TN1525	Convallatoxin K-毒毛旋花子配质-3-L-鼠李糖甙,铃兰毒苷	NF-κB; P-gp; PPAR	DNA Damage/DNA Repair; Membrane transporter/Ion channel; Metabolism; Neuroscience; NF-κB
	Convallatoxin 是从铃兰分离得到的一种强心苷。它是 P-糖蛋白底物，并识别 Val982 是参与其转运的重要氨基酸。它是配体诱导的 MOR 胞吞作用的增强剂，通过激活PPARγ和抑制NF-κB 改善结肠炎，具有抗炎和抗增殖特性。
T2799	(20S)-Protopanaxadiol 20-Epiprotopanaxadiol,20(S)-APPD,20 (S)-原人参二醇,原人参二醇	Apoptosis; Reactive Oxygen Species; P-gp	Apoptosis; Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism; Neuroscience; NF-κB
	(20S)-Protopanaxadiol (20-Epiprotopanaxadiol) 是人参皂甙的代谢产物，是一种凋亡诱导剂，抑制Akt 活性并诱导多种肿瘤细胞凋亡。
TCS2336	Evodine	P-gp	Membrane transporter/Ion channel; Neuroscience
	Evodine 是吴茱萸中的主要柠檬苦素，是P-gp 有效抑制剂，可通过保留抗氧化剂防御系统，针对谷氨酸诱导的毒性具有保护作用。
T19768	γ-Tocotrienol gamma Tocotrienol,gammaTocotrienol,gamma-Tocotrienol,D-gamma-Tocotrienol,Plastochromanol,γ-生育三烯酚	Others	Others
	γ-Tocotrienol (Plastochromanol) 是一种维生素 E 的活性形式。
T4085	Paris saponin VII 重楼皂苷 VII,Chonglou Saponin VII,Polyphyllin-VII,Dioscinin,Paris saponin-VII	Apoptosis; BCL; Others; PARP; p38 MAPK; Akt; Caspase; P-gp; Autophagy	Apoptosis; Autophagy; Chromatin/Epigenetic; Cytoskeletal Signaling; DNA Damage/DNA Repair; MAPK; Membrane transporter/Ion channel; Neuroscience; Others; PI3K/Akt/mTOR signaling; Proteases/Proteasome
	Paris saponin VII (Dioscini) 是从延龄草的根和根茎中分离的一种甾体皂苷。它减弱线粒体膜电位，增加凋亡相关蛋白的表达，并降低Bcl-2、caspase-9、caspase-3、PARP-1和p-Akt 的蛋白表达水平。它在 K562/ADR 细胞中诱导强烈的自噬，可研究白血病。
T15355	Fumitremorgin C 烟曲霉毒素c,12α-Fumitremorgin C	BCRP; Antibacterial; Antibiotic; ABC	Membrane transporter/Ion channel; Microbiology/Virology
	Fumitremorgin C (12α-Fumitremorgin C) 是ABCG2/BRCP 的选择性抑制剂。
TN3150	6,8-Diprenylnaringenin 6,8-二异戊二烯基柚皮素,Senegalensin,Lonchocarpol A	BCRP; ABC	Membrane transporter/Ion channel
	6,8-Diprenylnaringenin (Senegalensin) 是来自蛇麻草 Humulus lupulus 的天然产物。 6,8-Diprenylnaringenin 是一种乳腺癌耐药蛋白 (BCRP) 抑制剂，具有一定雌激素作用。
T2831	Glycocholic acid Glycocholate,甘氨胆酸,cholylglycine	Others; Endogenous Metabolite	Metabolism; Others
	Glycocholic acid (Glycocholate) 是一种胆汁酸，具有抗肿瘤活性，能够靶向作用于耐药泵和非耐药泵通路。
T3S2019	Lathyrol	Others	Others
	Lathyrol 是一种具有抗癌功能的天然产物。
T4461	3,5-Diiodo-L-thyronine 3,5-二碘-L-甲状腺素,Diiodothyronine	Thyroid hormone receptor(THR); Endogenous Metabolite	Endocrinology/Hormones; Metabolism
	3,5-Diiodo-L-thyronine (Diiodothyronine) 是内源性代谢产物的一种。
T3S2381	Perillene 3-Isohexenylfuran,紫苏烯,Perillen	Others; Antibacterial	Microbiology/Virology; Others
	Perillene (3-Isohexenylfuran) 是促进肠蠕动的药物中的活性成分，它对金黄色葡萄球菌和大肠杆菌具有很强的抗药性。
T5777	Phaseoloidin	Others	Others
	Phaseoloidin 是来自烟草细毛虫的高纯酸苷，有助于植物抵抗鳞翅目草食动物。它能够抑制Manduca sexta 和Spodoptera littoralis 的幼虫生长。它具有抗补体特性。
T4797	DEHP Bis(2-ethylhexyl) phthalate,邻苯二甲酸二(2-乙基己)酯	Others; Endogenous Metabolite	Metabolism; Others
	DEHP (Bis(2-ethylhexyl) phthalate) 是内源性代谢产物的一种。
T6S1842	Tenacissoside G Tenacissimoside A,通关藤苷G	Others; P-gp	Membrane transporter/Ion channel; Neuroscience; Others
	Tenacissoside G 是一种 C21 甾体，来自于Marsdenia tenacissima茎部。它可逆转 P-糖蛋白过度表达的多药耐药癌细胞的多药耐药。
T2A2486	3',4',5',5,7-Pentamethoxyflavone 5,7,3',4',5'-Pentamethoxyflavone	Nrf2	Immunology/Inflammation
	3',4',5',5,7-Pentamethoxyflavone 是从 Rutaceae 中发现的的一种天然黄铜类化合物，通过抑制Nrf2 通路克服化疗活性分子从而对癌细胞展现出耐药性。
T4A2399	Cinobufotalin 华蟾毒它灵,华蟾素	IL Receptor; Akt; MRP; P-gp	Cytoskeletal Signaling; Immunology/Inflammation; Membrane transporter/Ion channel; Neuroscience; PI3K/Akt/mTOR signaling
	Cinobufotalin 是一种从蟾蜍的皮肤分泌物中提取的强心类固醇或丁二烯内酯。它已被用作强心药，利尿药和止血药，也是潜在的抗肺癌药物。
T4785	Oxfenicine 4-羟基-L-苯甘氨酸,4-Hydroxy-L-phenylglycine	Others	Others
	Oxfenicine (4-Hydroxy-L-phenylglycine) 是具有口服活性的肉碱棕榈酰转移酶-1 抑制剂。它在缺血期间保护心脏免受坏死组织的损害。它可抑制心脏中脂肪酸的氧化。
T3208	Brevianamide F Cyclo-L-tryptophyl-L-proline,cyclo-(L-Trp-L-Pro),Cyclo(L-Pro-L-Trp)	BCRP; PI3K; Antibacterial	Membrane transporter/Ion channel; Microbiology/Virology; PI3K/Akt/mTOR signaling
	Brevianamide F (Cyclo(L-Pro-L-Trp)) 是一种从Colletotrichum gloeosporioides 中分离得到的真菌毒素，属于天然存在的 2,5-二酮哌嗪类，具有抗菌活性。它具有PI3Kα抑制活性，IC50值为 4.8 µM。
T6S0095	Genkwanin 7-O-Methylapigenin,Puddumetin,Apigenin 7-methyl ether,芫花素	Virus Protease	Microbiology/Virology
	Genkwanin (Apigenin 7-methyl ether) 是一种O-甲基化黄酮，有抗炎活性，通过被动扩散和多药耐药蛋白介导的外排机制转运。
TN1921	Meloside A 异牡荆素-2''-O-葡萄糖苷,Isovitexin 2''-O-glucoside,Isovitexin 2''-O-β-D-glucoside	Others	Others
	Meloside A (Isovitexin 2''-O-β-D-glucoside) 是一种从大麦中提取的苯丙烷类天然产物。 Meloside A 对过量的 UV-B 辐射具有抗氧化和保护作用，并与对病原体的抵抗力有关。
T15091	Decoyinine Decynylene,Angustmycin A
	Decoyinine (Decynylene) 是一种选择性的GMP 合成酶抑制剂，是一种新型的潜在微生物杀虫剂，是一种由透明链霉菌产生的次级代谢产物。Decoyinine 诱导水稻对小棕瓢虫Laodelphax striatellus 的抗性。
TN2256	Taccalonolide B 根薯酮内酯B,根薯酮内酯 B	Microtubule Associated	Cytoskeletal Signaling
	Taccalonolide B 是从广西裂果薯中分离得到的一种微管稳定剂，具有抗肿瘤活性。它抑制 SK-OV-3 细胞的生长，IC50 为 208 nM，在体外对过表达 P-糖蛋白 (Pgp) 和多药耐药蛋白 (MRP7) 的细胞系有效。
T0950	Neomycin sulfate Framycin sulfate,硫酸新霉素	Phospholipase; ribosome; Antibacterial; Antibiotic	Metabolism; Microbiology/Virology
	Neomycin sulfate (Framycin sulfate) 是一种广谱的氨基糖苷类抗生素。Neomycin sulfate 可以阻断细菌蛋白质的合成以发挥抗菌活性。Neomycin sulfate 常用于筛选具有 Neo 抗性基因的原核和真核细胞。
T1273	Diacerein 双醋瑞因,Diacerhein,Fisiodar,Diacetylrhein	IL Receptor; Interleukin	Immunology/Inflammation
	Diacerein (Fisiodar) 是一种慢效具有白介素-1β 抑制效果的蒽醌类化合物。
T2S0265	Robinin NSC 9222,刺槐素	TLR	Immunology/Inflammation
	Flavone glycoside from Robinia with antibacterial and diuretic properties; derived from kaempferol.The ability of robinin to reverse the multidrug resistance of the human colon cancer cell line Colo 320 expreβing MDR1/LRP was explored by monitoring their uptake of Rhodamine 123, but was shown to have minimal effect. Robinin (NSC-9222) was detected in lysates of the human breast cancer cell line MCF-7 using liquid chromatography-tandem maβ spectrometry.
T4S2128	Bilobetin 白果双黄酮,白果素	PKA; PPAR	DNA Damage/DNA Repair; Metabolism; Tyrosine Kinase/Adaptors
	Bilobetin 是银杏的活性成分，可改善胰岛素抵抗，增加肝脏对脂质的吸收和氧化，降低极低密度脂蛋白甘油三酯分泌和血液甘油三酯水平，增强组织中 β-氧化的酶的表达和活性，并减弱甘油三酯及其代谢产物的积累。它还增加了 PPARα的磷酸化，核转位和活性，并伴随着 cAMP 水平和 PKA 活性的升高。
TN6551	Tectoruside	Antioxidant	oxidation-reduction
	Tectoruside 是一种从鸢尾和豹纹百合中提取得到的酚酸糖苷，具有抗诱变和抗氧化活性，通过靶向ROS相关炎症和IRS-1通路来减弱棕榈酸酯诱导的内皮胰岛素抵抗。Tectoruside 可用于研究癌症。
T1022	Hygromycin B 潮霉素B,Hygrovetine	ribosome; Antibacterial; Antibiotic; Antifungal	Microbiology/Virology
	Hygromycin B (Hygrovetine) 是一种氨基糖苷类抗生素，通过干扰易位并导致 70S 核糖体的错误翻译来抑制蛋白质合成。Hygromycin B 可用于筛选转染 hph 或 hyg 抗性基因的原核或者真核细胞。
T6S1885	Benzoylmesaconine Mesaconine 14-benzoate,苯甲酰新乌头原碱	Others	Others
	Benzoylmesaconine (Mesaconine 14-benzoate) 是乌头汤最丰富的组分。其中乌头汤可用于研究类风湿性关节炎。
T6S0232	Eriodictyol 圣草酚,Huazhongilexone	Influenza Virus; DNA/RNA Synthesis; Nrf2; Endogenous Metabolite	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Immunology/Inflammation; Metabolism; Microbiology/Virology
	Eriodictyol (Huazhongilexone) 是从中草药中得到的一种黄酮类天然产物，具有抗氧化、抗炎和抗糖尿病作用。它还是一种流感依赖 RNA 的RNA 聚合酶抑制剂，IC50为 18 nM。它可诱导Nrf2信号通路。
T1181	Gefitinib ZD1839,吉非替尼	EGFR; Tyrosine Kinases; Autophagy	Angiogenesis; Autophagy; JAK/STAT signaling; Tyrosine Kinase/Adaptors
	Gefitinib (ZD1839) 是一种 EGFR 一代抑制剂，具有口服活性，抑制 EGFR 19 Del 和 L858R 突变。Gefitinib 具有抗肿瘤活性，用于治疗 EGFR 突变的非小细胞肺癌。Gefitinib 用药会产生 EGFR C797S 耐药突变。
T15097	Deoxynivalenol Vomitoxin,4-Deoxynivalenol
	Deoxynivalenol (Vomitoxin) 是一种单端孢菌素家族镰刀菌属产生的霉菌毒素，常见于受到污染的食物和饲料中。Deoxynivalenol 通过紧密连接处的细胞旁路来穿过肠粘膜。Deoxynivalenol 转运不受P-糖蛋白 (PgP) 或多药耐药相关蛋白 (MRP) 抑制剂的影响。Deoxynivalenol 通常会导致人类和动物腹泻、呕吐和胃肠道炎症。
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天然产物

Cat.No: T3881

Target: Integrin, Akt, PERK, AMPK

Cinnamoylglycine

Cat.No: T10815

Target: Endogenous Metabolite

Cat.No: TN1651

Target: Apoptosis, PARP, Reactive Oxygen Species, Caspase, CDK, P-gp

coniferyl ferulate

Cat.No: T3S0012

Target: P-gp, GST

Cat.No: T6670

Synonym: Silybin B,水飞蓟素

Target: SARS-CoV

Cat.No: TN4761

Target: P-gp

Cat.No: T2S0223

Synonym: 异橙黄酮,6-Demethoxynobiletin

Target: Antioxidant, HIV Protease, Antibacterial, P-gp

Cat.No: T2S0271

Synonym: 老刺木胺,Voacanginine

Target: Cannabinoid Receptor, P-gp

Cat.No: T3002

Synonym: 胡椒碱,1-Piperoylpiperidine,Bioperine

Target: P450, Endogenous Metabolite, P-gp, Autophagy

Cat.No: T2869

Synonym: Frangula emodin,大黄素

Target: SARS-CoV, Casein Kinase, Autophagy

Sinapine thiocyanate

Cat.No: T3392

Target: P-gp, AChE

Chrysosplenetin

Cat.No: TJS1159

Synonym: 猫眼草黄素,Chrysosptertin B

Target: P450, Ferroptosis, P-gp

Cat.No: T2S1200

Target: Antioxidant, P-gp, AChE

Cat.No: TL0006

Synonym: 菊苣酸,Dicaffeoyltartaric acid,Chicoric Acid

Target: Reactive Oxygen Species, HIV Protease

N-Hydroxypipecolic acid

Cat.No: T19458

Synonym: 1-Hydroxy-2-piperidinecarboxylic acid,NHP

Target: Others

(R)-5-Hydroxy-1,7-diphenylheptan-3-one

Cat.No: TN6339

Synonym: (5R)-Dihydroyashabushiketol,(R)-5-羟基-1,7-二苯基-3-庚酮

Target: Others

Cat.No: T4034

Synonym: Solamargin,δ-Solanigrine,澳洲茄边碱

Target: Apoptosis, p38 MAPK, P-gp, STAT

Hypophyllanthin

Cat.No: TN1757

Synonym: 叶下珠次素,(7S,8S,9R)-9-(3,4-二甲氧基苯基)-6,7,8,9-四氢-4-甲氧基-7,8-双(甲氧基甲基)萘并[1,2-D]-1,3-二恶茂

Target: Potassium Channel, Calcium Channel, P-gp

Cat.No: TN1525

Synonym: K-毒毛旋花子配质-3-L-鼠李糖甙,铃兰毒苷

Target: NF-κB, P-gp, PPAR

(20S)-Protopanaxadiol

Cat.No: T2799

Synonym: 20-Epiprotopanaxadiol,20(S)-APPD,20 (S)-原人参二醇,原人参二醇

Target: Apoptosis, Reactive Oxygen Species, P-gp

Cat.No: TCS2336

Target: P-gp

Cat.No: T19768

Synonym: gamma Tocotrienol,gammaTocotrienol,gamma-Tocotrienol,D-gamma-Tocotrienol,Plastochromanol,γ-生育三烯酚

Target: Others

Paris saponin VII

Cat.No: T4085

Synonym: 重楼皂苷 VII,Chonglou Saponin VII,Polyphyllin-VII,Dioscinin,Paris saponin-VII

Target: Apoptosis, BCL, Others, PARP, p38 MAPK, Akt, Caspase, P-gp, Autophagy

Fumitremorgin C

Cat.No: T15355

Synonym: 烟曲霉毒素c,12α-Fumitremorgin C

Target: BCRP, Antibacterial, Antibiotic, ABC

6,8-Diprenylnaringenin

Cat.No: TN3150

Synonym: 6,8-二异戊二烯基柚皮素,Senegalensin,Lonchocarpol A

Target: BCRP, ABC

Glycocholic acid

Cat.No: T2831

Synonym: Glycocholate,甘氨胆酸,cholylglycine

Target: Others, Endogenous Metabolite

Cat.No: T3S2019

Target: Others

3,5-Diiodo-L-thyronine

Cat.No: T4461

Synonym: 3,5-二碘-L-甲状腺素,Diiodothyronine

Target: Thyroid hormone receptor(THR), Endogenous Metabolite

Cat.No: T3S2381

Synonym: 3-Isohexenylfuran,紫苏烯,Perillen

Target: Others, Antibacterial

Cat.No: T5777

Target: Others

Cat.No: T4797

Synonym: Bis(2-ethylhexyl) phthalate,邻苯二甲酸二(2-乙基己)酯

Target: Others, Endogenous Metabolite

Tenacissoside G

Cat.No: T6S1842

Synonym: Tenacissimoside A,通关藤苷G

Target: Others, P-gp

3',4',5',5,7-Pentamethoxyflavone

Cat.No: T2A2486

Synonym: 5,7,3',4',5'-Pentamethoxyflavone

Target: Nrf2

Cat.No: T4A2399

Synonym: 华蟾毒它灵,华蟾素

Target: IL Receptor, Akt, MRP, P-gp

Cat.No: T4785

Synonym: 4-羟基-L-苯甘氨酸,4-Hydroxy-L-phenylglycine

Target: Others

Cat.No: T3208

Synonym: Cyclo-L-tryptophyl-L-proline,cyclo-(L-Trp-L-Pro),Cyclo(L-Pro-L-Trp)

Target: BCRP, PI3K, Antibacterial

Cat.No: T6S0095

Synonym: 7-O-Methylapigenin,Puddumetin,Apigenin 7-methyl ether,芫花素

Target: Virus Protease

Cat.No: TN1921

Synonym: 异牡荆素-2''-O-葡萄糖苷,Isovitexin 2''-O-glucoside,Isovitexin 2''-O-β-D-glucoside

Target: Others

Cat.No: T15091

Synonym: Decynylene,Angustmycin A

Taccalonolide B

Cat.No: TN2256

Synonym: 根薯酮内酯B,根薯酮内酯 B

Target: Microtubule Associated

Neomycin sulfate

Cat.No: T0950

Synonym: Framycin sulfate,硫酸新霉素

Target: Phospholipase, ribosome, Antibacterial, Antibiotic

Cat.No: T1273

Synonym: 双醋瑞因,Diacerhein,Fisiodar,Diacetylrhein

Target: IL Receptor, Interleukin

Cat.No: T2S0265

Synonym: NSC 9222,刺槐素

Target: TLR

Cat.No: T4S2128

Synonym: 白果双黄酮,白果素

Target: PKA, PPAR

Cat.No: TN6551

Target: Antioxidant

Cat.No: T1022

Synonym: 潮霉素B,Hygrovetine

Target: ribosome, Antibacterial, Antibiotic, Antifungal

Benzoylmesaconine

Cat.No: T6S1885

Synonym: Mesaconine 14-benzoate,苯甲酰新乌头原碱

Target: Others

Cat.No: T6S0232

Synonym: 圣草酚,Huazhongilexone

Target: Influenza Virus, DNA/RNA Synthesis, Nrf2, Endogenous Metabolite

Cat.No: T1181

Synonym: ZD1839,吉非替尼

Target: EGFR, Tyrosine Kinases, Autophagy

Cat.No: T15097

Synonym: Vomitoxin,4-Deoxynivalenol

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Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-03139	MDR1 Protein, Plasmodium falciparum, Recombinant (His & SUMO) Chloroquine resistance protein,MDR1,Multidrug r...	Plasmodium falciparum	E. coli
	Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells. MDR1 Protein, Plasmodium falciparum, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 54.2 kDa and the accession number is P13568.
TMPH-03609	Phosphinothricin N-acetyltransferase Protein, S. viridochromogenes, Recombinant (His & SUMO) pat,Phosphinothricin N-acetyltransferase,Phosphinothricin-	Streptomyces viridochromogenes	E. coli
	Inactivates phosphinothricin (PPT) by transfer of an acetyl group from acetyl CoA. This enzyme is an effector of phosphinothricin tripeptide (PTT or bialaphos) resistance. Phosphinothricin N-acetyltransferase Protein, S. viridochromogenes, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 36.6 kDa and the accession number is Q57146.
TMPJ-00871	BAR Protein, S. hygroscopicus, Recombinant bar,PPT N-acetyltransferase,Phosphinothricin-resistance<...	Streptomyces hygroscopicus	E. coli
	Phosphinothricin N-acetyltransferase (PAT) is an enzyme that acetylates the free NH2 group of L-phosphinothricin (L-PPT) in the presence of acetyl-CoA as a co-substrate. It is highly specific for L-PPT and does not acetylate other L-amino acids or structurally similar molecules. L-PPT is a glutamate analog that can inhibit glutamine synthetase activity in plants, resulting in the accumulation of ammonia to toxic levels and impairment of photosynthesis. The introduction of a PAT gene into a plant...
TMPH-03608	Phosphinothricin N-acetyltransferase Protein, S. viridochromogenes, Recombinant (His) Phosphinothricin N-acetyltransferase,Phosphinothricin-re...	Streptomyces viridochromogenes	P. pastoris (Yeast)
	Inactivates phosphinothricin (PPT) by transfer of an acetyl group from acetyl CoA. This enzyme is an effector of phosphinothricin tripeptide (PTT or bialaphos) resistance. Phosphinothricin N-acetyltransferase Protein, S. viridochromogenes, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 22.6 kDa and the accession number is Q57146.
TMPH-03604	Phosphinothricin N-acetyltransferase Protein, Streptomyces hygroscopicus, Recombinant (His) Phosphinothricin-resistance protein,Phosphinothrici...	Streptomyces hygroscopicus	E. coli
	Inactivates phosphinothricin (PPT) by transfer of an acetyl group from acetyl CoA. Can also acetylate demethylphosphinothricin but not PTT or glutamate. This enzyme is an effector of phosphinothricin tripeptide (PTT or bialaphos) resistance. Phosphinothricin N-acetyltransferase Protein, Streptomyces hygroscopicus, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 24.6 kDa and the accession number is P16426.
TMPH-00715	Mcr-1 Protein, E. coli, Recombinant (His & SUMO) Probable phosphatidylethanolamine transferase Mcr-1,Polymyxi...	E. coli	E. coli
	Mcr-1 Protein, E. coli, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 56.7 kDa and the accession number is A0A0R6L508.
TMPH-03678	Vaccinia virus (strain Copenhagen) OPG125 Protein (His & Myc) 62 kDa protein,Rifampicin resistance protein,Scaffo...	VACV	E. coli
	Vaccinia virus (strain Copenhagen) OPG125 Protein (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 33.2 kDa and the accession number is P68441.
TMPH-03750	SLC7A11 Protein, Human, Recombinant (His) SLC7A11,Calcium channel blocker resistance protein ...	Human	E. coli
	Sodium-independent, high-affinity exchange of anionic amino acids with high specificity for anionic form of cystine and glutamate.
TMPH-00981	ABCB1 Protein, Human, Recombinant (His) Multidrug resistance protein 1,P-glycoprotein 1,ATP...	Human	E. coli
	ABCB1 Protein, Human, Recombinant (His) is expressed in E. coli.
TMPH-01711	ABCC1 Protein, Human, Recombinant (His) MRP,ATP-binding cassette sub-family C member 1,Leukotriene C...	Human	E. coli
	ABCC1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 35.9 kDa and the accession number is P33527.
TMPH-00856	RPSA Protein, Human, Recombinant (His & Myc) 67 kDa laminin receptor,RPSA,Laminin-binding protein precurs...	Human	E. coli
	RPSA Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 37.7 kDa and the accession number is P08865.
TMPY-04069	Neurotrophin 3 Protein, Human, Recombinant NGF2,HDNF,NT-3,neurotrophin 3,NGF-2,NT3	Human	E. coli
	NTF3 (Neurotrophin 3) is a Protein Coding gene. The protein encoded by this gene is a member of the neurotrophin family, that controls the survival and differentiation of mammalian neurons. This protein is closely related to both nerve growth factor and brain-derived neurotrophic factor. NTF3 is a key mediator of neuronal development during the early neurogenic period. NTF3 is a novel target gene of POU3F2 and that the POU3F2/NTF3 pathway plays a role in the process of neuronal differentiation. ...
TMPY-01009	TGFBI Protein, Human, Recombinant (His) CDG2,CSD,EBMD,CSD1,CDGG1,CSD3,transforming growth factor, be...	Human	HEK293 Cells
	TGFBI is an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. TGFBI plays a role in cell-collagen interactions and may be involved in endochondral bone formation in cartilage. TGFBI is induced by transforming growth factor-beta and acts to inhibit cell adhesion. Mutations in TGFBI are associated with multiple types of corneal dys...
TMPY-03962	AFM Protein, Human, Recombinant (His) afamin,ALBA,ALB2,ALF	Human	HEK293 Cells
	Afamin is an 87 kDa glycoprotein with five predicted N-glycosylation sites. Afamin's glycan abundance contributes to conformational and chemical inhomogeneity presenting great challenges for molecular structure determination. Afamin, a human plasma glycoprotein and putative transporter of hydrophobic molecules, has been shown to act as extracellular chaperone for poorly soluble, acylated Wnt proteins, forming a stable, soluble complex with functioning Wnt proteins. The 2.1-Å crystal structure of...
TMPY-00566	CCL18 Protein, Human, Recombinant (His) PARC,CCL18,CKb7,DC-CK1,chemokine (C-C motif) ligand 18,MIP-4...	Human	P. pastoris (Yeast)
	CCL18 is a chemotactic cytokine involved in the pathogenesis and progression of various disorders, including cancer. Proof showed high levels of CCL18 in the serum of epithelial ovarian carcinoma patients suggesting its potential as a circulating biomarker. CCL18 chemokine has an important role in chemokine-mediated tumor metastasis, and may serve as a potential predictor for poor survival outcomes for ovarian cancer. (CCL18) is predominantly secreted by M2-tumor associated macrophages (TAMs) a...
TMPH-00753	UspD Protein, E. coli, Recombinant (His) uspD,Universal stress protein D	E. coli	E. coli
	Required for resistance to DNA-damaging agents.
TMPH-02373	Metallo-beta-lactamase type 2 Protein, Klebsiella pneumoniae, Recombinant (His) Metallo-beta-lactamase type 2,B2 metallo-beta-lactamase,Meta...	Klebsiella pneumoniae	E. coli
	Confers resistance to the different beta-lactams antibiotics (penicillin, cephalosporin and carbapenem) via the hydrolysis of the beta-lactam ring. Does not confer resistance to the polymixin colistin or the fluoroquinolone ciprofloxacin.
TMPH-03717	YopE Protein, Yersinia enterocolitica, Recombinant (His) yopE,Outer membrane virulence protein YopE	Yersinia enterocolitica	E. coli
	Essential virulence determinant; cytotoxic effector, involved in resistance to phagocytosis.
TMPH-00738	TetR5 Protein, E. coli, Recombinant (His) Tetracycline repressor protein class E,tetR	E. coli	E. coli
	TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites. TetR5 Protein, E. coli, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 27.7 kDa and the accession number is P21337.
TMPH-00737	TetR2 Protein, E. coli, Recombinant (His & SUMO) tetR,Tetracycline repressor protein class B from transposon ...	E. coli	E. coli
	TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites. TetR2 Protein, E. coli, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 39.4 kDa and the accession number is P04483.
TMPH-00584	Beta-lactamase CTX-M-1 Protein, E. coli, Recombinant (His) men1,Beta-lactamase MEN-1,Cefotaximase 1,Beta-lactamase CTX-...	E. coli	E. coli
	Broad spectrum beta-lactamase which confers resistance to penicillins, as well as first, second and third-generation cephalosporins.
TMPH-00585	Beta-lactamase CTX-M-1 Protein, E. coli, Recombinant (Yeast, His) Beta-lactamase MEN-1,Cefotaximase 1,bla,men1,Beta-lactamase ...	E. coli	P. pastoris (Yeast)
	Broad spectrum beta-lactamase which confers resistance to penicillins, as well as first, second and third-generation cephalosporins.
TMPH-02371	SHV-5 Protein, Klebsiella pneumoniae, Recombinant (His & Myc) Beta-lactamase SHV-5,bla	Klebsiella pneumoniae	E. coli
	SHV enzymes hydrolyze broad spectrum cephalosporins notably cefotaxime and ceftazidime. SHV-5 causes particularly high levels of resistance to aztreonam and ceftazidime.
TMPH-00774	SAM22 Protein, Glycine max, Recombinant (His) Pathogenesis-related protein 10,PR-10,Stress-induced protein...	Glycine max	P. pastoris (Yeast)
	Involved in disease resistance. SAM22 Protein, Glycine max, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 18.8 kDa and the accession number is P26987.
TMPH-00587	Beta-lactamase TEM Protein, E. coli, Recombinant (His & SUMO) IRT-4,TEM-16/CAZ-7,Penicillinase,Beta-lactamase TEM,TEM-2,TE...	E. coli	E. coli
	TEM-type are the most prevalent beta-lactamases in enterobacteria; they hydrolyze the beta-lactam bond in susceptible beta-lactam antibiotics, thus conferring resistance to penicillins and cephalosporins. TEM-3 and TEM-4 are capable of hydrolyzing cefotaxime and ceftazidime. TEM-5 is capable of hydrolyzing ceftazidime. TEM-6 is capable of hydrolyzing ceftazidime and aztreonam. TEM-8/CAZ-2, TEM-16/CAZ-7 and TEM-24/CAZ-6 are markedly active against ceftazidime. IRT-4 shows resistance to beta-lacta...
TMPH-00586	Beta-lactamase TEM Protein, E. coli, Recombinant (His) IRT-4,Penicillinase,TEM-2,TEM-16/CAZ-7,Beta-lactamase TEM,TE...	E. coli	P. pastoris (Yeast)
	TEM-type are the most prevalent beta-lactamases in enterobacteria; they hydrolyze the beta-lactam bond in susceptible beta-lactam antibiotics, thus conferring resistance to penicillins and cephalosporins. TEM-3 and TEM-4 are capable of hydrolyzing cefotaxime and ceftazidime. TEM-5 is capable of hydrolyzing ceftazidime. TEM-6 is capable of hydrolyzing ceftazidime and aztreonam. TEM-8/CAZ-2, TEM-16/CAZ-7 and TEM-24/CAZ-6 are markedly active against ceftazidime. IRT-4 shows resistance to beta-lacta...
TMPH-03360	PTMA Protein, Rat, Recombinant (His) Prothymosin alpha,Ptma	Rat	P. pastoris (Yeast)
	Prothymosin alpha may mediate immune function by conferring resistance to certain opportunistic infections. PTMA Protein, Rat, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 14.3 kDa and the accession number is P06302.
TMPH-03473	UspA Protein, Salmonella typhi, Recombinant (His) Universal stress protein A,uspA	Salmonella typhi	E. coli
	Required for resistance to DNA-damaging agents. UspA Protein, Salmonella typhi, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 19.9 kDa and the accession number is Q8Z268.
TMPH-00035	Polyphenol oxidase 2 Protein, Agaricus bisporus, Recombinant (His) Tyrosinase 2,Cresolase 2,PPO2,Polyphenol oxidase 2	Agaricus bisporus	Baculovirus Insect Cells
	Copper-containing oxidase that catalyzes both the o-hydroxylation of monophenols and the subsequent oxidation of the resulting o-diphenols into reactive o-quinones, which evolve spontaneously to produce intermediates, which associate in dark brown pigments. Involved in the initial step of melanin synthesis. Melanins constitute a mechanism of defense and resistance to stress such as UV radiations, free radicals, gamma rays, dehydratation and extreme temperatures, and contribute to the fungal cell...
TMPH-02379	arnT Protein, Klebsiella pneumoniae, Recombinant (His) Lipid IV(A) 4-amino-4-deoxy-L-arabinosyltransferase,4-amino-...	Klebsiella pneumoniae	E. coli
	Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.
TMPY-03049	GALNT10 Protein, Human, Recombinant (His) GALNACT10,PPGANTASE10,polypeptide N-acetylgalactosaminyltran...	Human	HEK293 Cells
	Ectopic expression and knockdown studies showed that GALNT10 indeed promotes proliferation and apoptosis resistance of hepatoma cells in a glycosyltransferase-dependent manner. The genetic variants on LEKR1 and GALNT10 genes have been associated with control of adiposity and weight.
TMPH-03518	ACP Protein, S. aureus, Recombinant (GST) acpP,Fatty acid synthase acyl carrier protein,Acyl carrier p...	Staphylococcus aureus	E. coli
	Carrier of the growing fatty acid chain in fatty acid biosynthesis. Is able to confer high methicillin resistance to S.aureus when overproduced. ACP Protein, S. aureus, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 35.5 kDa and the accession number is P0A001.
TMPH-03519	ACP Protein, S. aureus, Recombinant (His) Cytosolic-activating factor,Fatty acid synthase acyl carrier...	Staphylococcus aureus	P. pastoris (Yeast)
	Carrier of the growing fatty acid chain in fatty acid biosynthesis. Is able to confer high methicillin resistance to S.aureus when overproduced. ACP Protein, S. aureus, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 10.5 kDa and the accession number is P0A001.
TMPH-03520	ACP Protein, S. aureus, Recombinant (His & SUMO) acpP,Cytosolic-activating factor,Fatty acid synthase acyl ca...	Staphylococcus aureus	E. coli
	Carrier of the growing fatty acid chain in fatty acid biosynthesis. Is able to confer high methicillin resistance to S.aureus when overproduced. ACP Protein, S. aureus, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 24.5 kDa and the accession number is P0A001.
TMPJ-00710	ALDH1A2 Protein, Human, Recombinant (His) RALDH(II),Retinal dehydrogenase 2,RALDH2,ALDH1A2,Retinaldehy...	Human	E. coli
	Aldehyde dehydrogenase 1 family member A2 (ALDH1A2), also known as retinaldehyde dehydrogenase 2 (RALDH2), belongs to the aldehyde dehydrogenase family which contains two members, the ALDH1 s (ALDH1A1, ALDH1A2 and ALDH1A3) and the 9-cis retinaldehyde dehydrogenase ALDH8 s. ALDH1A2 is key enzyme that catalyzes the synthesis of retinoic acid (RA) from retinaldehyde. RA is a paracrine hormone signaling molecule that functions in developing and adult tissues. ALDH1A2 was also found to regulate norma...
TMPY-02660	Resistin Protein, Mouse, Recombinant (hFc) resistin,Xcp4,ADSF,Fizz3,Rstn	Mouse	HEK293 Cells
	Resistin is an adipocytokine, which has been studied for its role in insulin resistance and recently in inflammation. The RETN and CAP1 polymorphisms and gene expression may be potential biomarkers for breast cancer risk. Resistin (RETN), recently found to be relevant to inflammation and inflammatory disorders.
TMPH-01847	Parathymosin Protein, Human, Recombinant (His & Myc) Parathymosin,PTMS	Human	E. coli
	Parathymosin may mediate immune function by blocking the effect of prothymosin alpha which confers resistance to certain opportunistic infections. Parathymosin Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 18.8 kDa and the accession number is P20962.
TMPH-03488	Metallo-beta-lactamase type 2 Protein, Serratia marcescens, Recombinant (His & Myc) Metallo-beta-lactamase type 2,BLA-IMP,Metallo-beta-lactamase...	Serratia marcescens	E. coli
	Confers resistance to the different beta-lactams antibiotics (penicillin, cephalosporin and carbapenem) via the hydrolysis of the beta-lactam ring. Metallo-beta-lactamase type 2 Protein, Serratia marcescens, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 32.6 kDa and the accession number is P52699.
TMPH-03053	Hydrophobin Protein, Neosartorya fumigata, Recombinant (B2M & His) rodA,Rodlet protein,Hydrophobin	Neosartorya fumigata	E. coli
	Cell wall protein regularly arranged in interwoven fascicules of clustered proteinaceous microfibrils, or rodlets, to form the outer spore coat protein. It is involved in resistance to environmental stress and may well be associated with conidial hydrophobicity. It is important in the morphogenesis of the dispersible conidia.
TMPH-02463	HMf-2 Protein, Methanothermus fervidus, Recombinant (His) Archaeal histone B,hmfB,DNA-binding protein HMf-2	Methanothermus fervidus	E. coli
	Binds and compacts DNA (95 to 150 base pairs) to form nucleosome-like structures that contain positive DNA supercoils. Increases the resistance of DNA to thermal denaturation in vitro. HMf-2 Protein, Methanothermus fervidus, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 11.7 kDa and the accession number is P19267.
TMPH-02462	HMf-1 Protein, Methanothermus fervidus, Recombinant (His & Myc) Archaeal histone A,hmfA,DNA-binding protein HMf-1	Methanothermus fervidus	E. coli
	Binds and compacts DNA (95 to 150 base pairs) to form nucleosome-like structures that contain positive DNA supercoils. Increases the resistance of DNA to thermal denaturation. HMf-1 Protein, Methanothermus fervidus, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 14.9 kDa and the accession number is P48781.
TMPH-00714	SapA Protein, E. coli, Recombinant (His & Myc) sapA,Probable ABC transporter periplasmic-binding protein Sa...	E. coli	E. coli
	Not part of a putrescine export system. Very similar to a S.typhimurium protein implicated in antimicrobial peptide resistance, but the SapBCDF operon in E.coli is implicated in putrescine export. SapA Protein, E. coli, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 66.9 kDa and the accession number is Q47622.
TMPH-02153	Sulfiredoxin-1 Protein, Human, Recombinant (His & Myc) SRXN1,Sulfiredoxin-1	Human	E. coli
	Contributes to oxidative stress resistance by reducing cysteine-sulfinic acid formed under exposure to oxidants in the peroxiredoxins PRDX1, PRDX2, PRDX3 and PRDX4. Does not act on PRDX5 or PRDX6. May catalyze the reduction in a multi-step process by acting both as a specific phosphotransferase and a thioltransferase.
TMPK-00516	BST1 Protein, Cynomolgus, Recombinant (His) Bp-3,CD157,Bst1,BST-1,Ly65,Bp3,Antigen BP3	Cynomolgus	HEK293 Cells
	BST1 overexpression conferred resistance to sphingosine in yeast. BST1 deletion produced sensitivity to exogenous D-erythro-sphingosine and phytosphingosine and intracellular accumulation of sphingosine 1-phosphate upon exposure to exogenous sphingosine. sphingoid base metabolism is similar in all eukaryotes and suggests that yeast genetics may be useful in the isolation and identification of other genes involved in sphingolipid signaling and metabolism.
TMPH-00079	Beta-amylase 3, chloroplastic Protein, Arabidopsis thaliana, Recombinant (His) BAM3,CTBMY,1,4-alpha-D-glucan maltohydrolase,Beta-amylase 3,...	Arabidopsis thaliana	E. coli
	Beta-amylase activity. No alpha-amylase activity. Involved in cold resistance. Mediates the accumulation of maltose upon freezing stress, thus contributing to the protection of the photosynthetic electron transport chain. Plays a role in the circadian-regulated starch degradation and maltose metabolism in chloroplasts, especially at night. More active on phosphorylated glucan. Interacts directly with starch or other alpha-1,4-glucan.
TMPJ-00932	PBLD Protein, Human, Recombinant (His) MAWBP,MAWD-Binding Protein,PBLD,MAWDBP,Unknown Protein 32 Fr...	Human	E. coli
	Phenazine Biosynthesis-Like Domain-Containing protein (PBLD) belongs to the phenazine biosynthesis-like protein (PhzF) family, which is expressed in most tissues. PBLD takes part in the MAPK signaling pathway, and is involved in multiple basic cellular functions. The expression of PBLD can be increased in several disease processes, including insulin resistance, folate deficiency and hypotension.
TMPH-00169	PBP 3 Protein, Bacillus subtilis, Recombinant (His) Penicillin-binding protein 3,PSPB20,Penicillin-binding prote...	Bacillus subtilis	E. coli
	Penicillin-binding proteins (PBPs) function in the late steps of murein biosynthesis. Probably required for both cortical and vegetative peptidoglycan synthesis. Although not usually required for cell division, in the absence of PBP 2B (pbpB) it becomes essential. Confers resistance to oxacillin and cephalexin. PBP 3 Protein, Bacillus subtilis, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 29.2 kDa and the accession number is P429...
TMPY-00481	AKR1C4 Protein, Human, Recombinant (His) aldo-keto reductase family 1, member C4,3-alpha-HSD,DD4,CHDR...	Human	E. coli
	Aldo-keto reductases comprise of AKR1C1-AKR1C4, four enzymes that catalyze NADPH dependent reductions and have been implicated in biosynthesis, intermediary metabolism, and detoxification. there is a strong correlation between the expression levels of these family members and the malignant transformation as well as the resistance to cancer therapy. Type I human hepatic 3alpha-hydroxysteroid dehydrogenase (AKR1C4) plays a significant role in bile acid biosynthesis, steroid hormone metabolism, an...
TMPH-02866	RBBP9 Protein, Mouse, Recombinant (His) Retinoblastoma-binding protein 9,Putative hydrolase RBBP9,B5...	Mouse	P. pastoris (Yeast)
	Serine hydrolase whose substrates have not been identified yet. May negatively regulate basal or autocrine TGF-beta signaling by suppressing SMAD2-SMAD3 phosphorylation. May play a role in the transformation process due to its capacity to confer resistance to the growth-inhibitory effects of TGF-beta through interaction with RB1 and the subsequent displacement of E2F1. RBBP9 Protein, Mouse, Recombinant (His) is expressed in yeast with C-6xHis tag. The predicted molecular weight is 22.4 kDa and t...
TMPH-00175	YuaB Protein, Bacillus subtilis, Recombinant (His & SUMO) Biofilm-surface layer protein A,bslA,ORF-1	Bacillus subtilis	E. coli
	Involved in biofilm formation. Self-polymerizes and forms a layer on the surface of biofilms that confers hydrophobicity to the biofilm. The layer is stable and capable of resistance to high mechanical force compression. Required for complex colony architecture. May function synergistically with exopolysaccharides and TasA amyloid fibers to facilitate the assembly of the biofilm matrix. YuaB Protein, Bacillus subtilis, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xH...
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重组蛋白

MDR1 Protein, Plasmodium falciparum, Recombinant (His & SUMO)

Cat.No: TMPH-03139

Species: Plasmodium falciparum

Expression System: E. coli

Phosphinothricin N-acetyltransferase Protein, S. viridochromogenes, Recombinant (His & SUMO)

Cat.No: TMPH-03609

Species: Streptomyces viridochromogenes

Expression System: E. coli

BAR Protein, S. hygroscopicus, Recombinant

Cat.No: TMPJ-00871

Species: Streptomyces hygroscopicus

Expression System: E. coli

Phosphinothricin N-acetyltransferase Protein, S. viridochromogenes, Recombinant (His)

Cat.No: TMPH-03608

Species: Streptomyces viridochromogenes

Expression System: P. pastoris (Yeast)

Phosphinothricin N-acetyltransferase Protein, Streptomyces hygroscopicus, Recombinant (His)

Cat.No: TMPH-03604

Species: Streptomyces hygroscopicus

Expression System: E. coli

Mcr-1 Protein, E. coli, Recombinant (His & SUMO)

Cat.No: TMPH-00715

Species: E. coli

Expression System: E. coli

Vaccinia virus (strain Copenhagen) OPG125 Protein (His & Myc)

Cat.No: TMPH-03678

Species: VACV

Expression System: E. coli

SLC7A11 Protein, Human, Recombinant (His)

Cat.No: TMPH-03750

Species: Human

Expression System: E. coli

ABCB1 Protein, Human, Recombinant (His)

Cat.No: TMPH-00981

Species: Human

Expression System: E. coli

ABCC1 Protein, Human, Recombinant (His)

Cat.No: TMPH-01711

Species: Human

Expression System: E. coli

RPSA Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-00856

Species: Human

Expression System: E. coli

Neurotrophin 3 Protein, Human, Recombinant

Cat.No: TMPY-04069

Species: Human

Expression System: E. coli

TGFBI Protein, Human, Recombinant (His)

Cat.No: TMPY-01009

Species: Human

Expression System: HEK293 Cells

AFM Protein, Human, Recombinant (His)

Cat.No: TMPY-03962

Species: Human

Expression System: HEK293 Cells

CCL18 Protein, Human, Recombinant (His)

Cat.No: TMPY-00566

Species: Human

Expression System: P. pastoris (Yeast)

UspD Protein, E. coli, Recombinant (His)

Cat.No: TMPH-00753

Species: E. coli

Expression System: E. coli

Metallo-beta-lactamase type 2 Protein, Klebsiella pneumoniae, Recombinant (His)

Cat.No: TMPH-02373

Species: Klebsiella pneumoniae

Expression System: E. coli

YopE Protein, Yersinia enterocolitica, Recombinant (His)

Cat.No: TMPH-03717

Species: Yersinia enterocolitica

Expression System: E. coli

TetR5 Protein, E. coli, Recombinant (His)

Cat.No: TMPH-00738

Species: E. coli

Expression System: E. coli

TetR2 Protein, E. coli, Recombinant (His & SUMO)

Cat.No: TMPH-00737

Species: E. coli

Expression System: E. coli

Beta-lactamase CTX-M-1 Protein, E. coli, Recombinant (His)

Cat.No: TMPH-00584

Species: E. coli

Expression System: E. coli

Beta-lactamase CTX-M-1 Protein, E. coli, Recombinant (Yeast, His)

Cat.No: TMPH-00585

Species: E. coli

Expression System: P. pastoris (Yeast)

SHV-5 Protein, Klebsiella pneumoniae, Recombinant (His & Myc)

Cat.No: TMPH-02371

Species: Klebsiella pneumoniae

Expression System: E. coli

SAM22 Protein, Glycine max, Recombinant (His)

Cat.No: TMPH-00774

Species: Glycine max

Expression System: P. pastoris (Yeast)

Beta-lactamase TEM Protein, E. coli, Recombinant (His & SUMO)

Cat.No: TMPH-00587

Species: E. coli

Expression System: E. coli

Beta-lactamase TEM Protein, E. coli, Recombinant (His)

Cat.No: TMPH-00586

Species: E. coli

Expression System: P. pastoris (Yeast)

PTMA Protein, Rat, Recombinant (His)

Cat.No: TMPH-03360

Species: Rat

Expression System: P. pastoris (Yeast)

UspA Protein, Salmonella typhi, Recombinant (His)

Cat.No: TMPH-03473

Species: Salmonella typhi

Expression System: E. coli

Polyphenol oxidase 2 Protein, Agaricus bisporus, Recombinant (His)

Cat.No: TMPH-00035

Species: Agaricus bisporus

Expression System: Baculovirus Insect Cells

arnT Protein, Klebsiella pneumoniae, Recombinant (His)

Cat.No: TMPH-02379

Species: Klebsiella pneumoniae

Expression System: E. coli

GALNT10 Protein, Human, Recombinant (His)

Cat.No: TMPY-03049

Species: Human

Expression System: HEK293 Cells

ACP Protein, S. aureus, Recombinant (GST)

Cat.No: TMPH-03518

Species: Staphylococcus aureus

Expression System: E. coli

ACP Protein, S. aureus, Recombinant (His)

Cat.No: TMPH-03519

Species: Staphylococcus aureus

Expression System: P. pastoris (Yeast)

ACP Protein, S. aureus, Recombinant (His & SUMO)

Cat.No: TMPH-03520

Species: Staphylococcus aureus

Expression System: E. coli

ALDH1A2 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00710

Species: Human

Expression System: E. coli

Resistin Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-02660

Species: Mouse

Expression System: HEK293 Cells

Parathymosin Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-01847

Species: Human

Expression System: E. coli

Metallo-beta-lactamase type 2 Protein, Serratia marcescens, Recombinant (His & Myc)

Cat.No: TMPH-03488

Species: Serratia marcescens

Expression System: E. coli

Hydrophobin Protein, Neosartorya fumigata, Recombinant (B2M & His)

Cat.No: TMPH-03053

Species: Neosartorya fumigata

Expression System: E. coli

HMf-2 Protein, Methanothermus fervidus, Recombinant (His)

Cat.No: TMPH-02463

Species: Methanothermus fervidus

Expression System: E. coli

HMf-1 Protein, Methanothermus fervidus, Recombinant (His & Myc)

Cat.No: TMPH-02462

Species: Methanothermus fervidus

Expression System: E. coli

SapA Protein, E. coli, Recombinant (His & Myc)

Cat.No: TMPH-00714

Species: E. coli

Expression System: E. coli

Sulfiredoxin-1 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-02153

Species: Human

Expression System: E. coli

BST1 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-00516

Species: Cynomolgus

Expression System: HEK293 Cells

Beta-amylase 3, chloroplastic Protein, Arabidopsis thaliana, Recombinant (His)

Cat.No: TMPH-00079

Species: Arabidopsis thaliana

Expression System: E. coli

PBLD Protein, Human, Recombinant (His)

Cat.No: TMPJ-00932

Species: Human

Expression System: E. coli

PBP 3 Protein, Bacillus subtilis, Recombinant (His)

Cat.No: TMPH-00169

Species: Bacillus subtilis

Expression System: E. coli

AKR1C4 Protein, Human, Recombinant (His)

Cat.No: TMPY-00481

Species: Human

Expression System: E. coli

RBBP9 Protein, Mouse, Recombinant (His)

Cat.No: TMPH-02866

Species: Mouse

Expression System: P. pastoris (Yeast)

YuaB Protein, Bacillus subtilis, Recombinant (His & SUMO)

Cat.No: TMPH-00175

Species: Bacillus subtilis

Expression System: E. coli

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Cat. No.	Product Name	Target	Signaling Pathways
TMID-0058	Glycocholic acid-d4
	Glycocholic acid-d4 是 Glycocholic acid 的氘代化合物。Glycocholic acid 的 CAS 号为 475-31-0。Glycocholic acid 是一种胆汁酸，具有抗肿瘤活性，能够靶向作用于耐药泵和非耐药泵通路。
TMIH-0297	Ledipasvir-d6
	Ledipasvir-d6 是 Ledipasvir 的氘代化合物。Ledipasvir 的 CAS 号为 1256388-51-8。Ledipasvir 是一种丙型肝炎病毒 NS5A 抑制剂。它也是 P-糖蛋白抑制剂和乳腺癌抗性蛋白抑制剂。
TMIJ-0506	Bis(2-ethylhexyl) Phthalate-d4
	Bis(2-ethylhexyl) Phthalate-d4 是 Bis(2-ethylhexyl) Phthalate 的氘代化合物。Bis(2-ethylhexyl) Phthalate 的 CAS 号为 117-81-7。Bis(2-ethylhexyl) phthalate 是内源性代谢产物的一种。
T70808	Cabazitaxel-d6
	Cabazitaxel-d6 is a deuterium labeled cabazitaxel. Cabazitaxel is a semi-synthetic derivative of the natural taxoid 10-deacetylbaccatin III with potential antineoplastic activity. Cabazitaxel binds to and stabilizes tubulin, resulting in the inhibition of microtubule depolymerization and cell division, cell cycle arrest in the G2/M phase, and the inhibition of tumor cell proliferation. Unlike other taxane compounds, this agent is a poor substrate for the membrane-associated, multidrug resistance...
TMIJ-0051	Hexanoic-d11 acid
	Hexanoic-d11 acid 是 Hexanoic acid 的氘代化合物。Hexanoic acid 的 CAS 号为 142-62-1。Caproic acid 是一种无色油状液体，闻起来像奶酪。它是一种天然存在于各种动物脂肪和油中的脂肪酸。它是一种抗性引发诱导剂，可保护番茄植物免受灰霉病菌的侵害。
TMID-0070	Amiodarone-d10 Hydrochloride
	Amiodarone-d10 Hydrochloride 是 Amiodarone Hydrochloride 的氘代化合物。Amiodarone Hydrochloride 的 CAS 号为 19774-82-4。Amiodarone hydrochloride是一种抗心绞痛和 III 类抗心律失常药物，通过抑制钾通道和电压门控钠通道来增加心室和心房肌肉作用的持续时间，可导致心率和血管阻力降低。它通过成纤维细胞中的ERK1/2和p38 MAPK信号传导诱导细胞增殖和肌成纤维细胞分化，可研究室上性和室性心律失常。
TMID-0069	Amiodarone-d4 HCl
	Amiodarone-d4 HCl 是 Amiodarone HCl 的氘代化合物。Amiodarone HCl 的 CAS 号为 19774-82-4。Amiodarone hydrochloride是一种抗心绞痛和 III 类抗心律失常药物，通过抑制钾通道和电压门控钠通道来增加心室和心房肌肉作用的持续时间，可导致心率和血管阻力降低。它通过成纤维细胞中的ERK1/2和p38 MAPK信号传导诱导细胞增殖和肌成纤维细胞分化，可研究室上性和室性心律失常。
T71981	Gliclazide-d4
	Gliclazide-d4 is intended for use as an internal standard for the quantification of gliclazide by GC- or LC-MS. Gliclazide is a sulfonylurea and an inhibitor of pancreatic β-cell ATP-sensitive potassium (KATP) channels. It is selective for pancreatic β-cell over cardiac and arterial smooth muscle cell KATP channels. Gliclazide (5 μM) increases insulin-induced glucose uptake and glucose transporter 4 (GLUT4) translocation to the plasma membrane in a differentiated 3T3L1 adipocyte model of insulin...
T71402	Nicorandil-d4
	Nicorandil-d4 is intended for use as an internal standard for the quantification of nicorandil by GC- or LC-MS. Nicorandil is an activator of sulfonylurea receptor 2B (SUR2B) linked to ATP-sensitive potassium channel Kir6.2 (EC50 = ~10 µM) and a nitric oxide (NO) donor. It is selective for SUR2B/Kir6.2 over the SUR2A/Kir6.2 channel (EC50 = >500 µM). Nicorandil activates soluble guanylate cyclase in a cell-free assay and relaxes partially depolarized isolated bovine coronary artery strips (EC50 =...
TMIJ-0199	Tauroursodeoxycholic-d4 Acid Tauroursodiol-d4
	Tauroursodeoxycholic-d4 Acid 是 Tauroursodeoxycholic Acid 的氘代化合物。Tauroursodeoxycholic Acid 的 CAS 号为 14605-22-2。Tauroursodeoxycholate，又称 ursodoxicoltaurine，是一种高度亲水性的三级胆汁酸，在人体内以低浓度产生。Tauroursodeoxycholate 是 ursodeoxycholic acid 更亲水的形式，而 ursodeoxycholic acid 是人类体内自然产生的更丰富的胆汁酸。Tauroursodeoxycholate 正在研究用于几种疾病，如原发性胆汁性肝硬化(PBC)、胰岛素抵抗、淀粉样变性、囊性纤维化、胆汁淤滞和肌萎缩性侧索硬化症。
TMIH-0552	Tauroursodeoxycholic Acid-d4 Sodium Salt
	Tauroursodeoxycholic Acid-d4 Sodium Salt 是 Tauroursodeoxycholic Acid Sodium Salt 的氘代化合物。Tauroursodeoxycholic Acid Sodium Salt 的 CAS 号为 14605-22-2。Tauroursodeoxycholate，又称 ursodoxicoltaurine，是一种高度亲水性的三级胆汁酸，在人体内以低浓度产生。Tauroursodeoxycholate 是 ursodeoxycholic acid 更亲水的形式，而 ursodeoxycholic acid 是人类体内自然产生的更丰富的胆汁酸。Tauroursodeoxycholate 正在研究用于几种疾病，如原发性胆汁性肝硬化(PBC)、胰岛素抵抗、淀粉样变性、囊性纤维化、胆汁淤滞和肌萎缩性侧索硬化症。
TMIJ-0197	Tauroursodeoxycholic-2,2,3,4,4-d5 Acid
	Tauroursodeoxycholic-2,2,3,4,4-d5 Acid 是 Tauroursodeoxycholic Acid 的氘代化合物。Tauroursodeoxycholic Acid 的 CAS 号为 14605-22-2。Tauroursodeoxycholate，又称 ursodoxicoltaurine，是一种高度亲水性的三级胆汁酸，在人体内以低浓度产生。Tauroursodeoxycholate 是 ursodeoxycholic acid 更亲水的形式，而 ursodeoxycholic acid 是人类体内自然产生的更丰富的胆汁酸。Tauroursodeoxycholate 正在研究用于几种疾病，如原发性胆汁性肝硬化(PBC)、胰岛素抵抗、淀粉样变性、囊性纤维化、胆汁淤滞和肌萎缩性侧索硬化症。
TMID-0254	Linalool-d3
	Linalool-d3 是 Linalool 的氘代化合物。Linalool 的 CAS 号为 78-70-6。Linalool 是存在芫荽等植物中的单萜类天然产物，是竞争性NMDA受体拮抗剂，具有抗肿瘤和抗心脏毒性的作用。它通过激活 Nrf2 诱导抗氧化防御和通过抑制 NF-κB 减少炎症反应来保护其免受 LPS/GalN 诱导的肝损伤，具有镇痛、抗菌和抗炎的特性。

同位素标记化合物

Glycocholic acid-d4

Cat.No: TMID-0058

Cat.No: TMIH-0297

Bis(2-ethylhexyl) Phthalate-d4

Cat.No: TMIJ-0506

Cat.No: T70808

Hexanoic-d11 acid

Cat.No: TMIJ-0051

Amiodarone-d10 Hydrochloride

Cat.No: TMID-0070

Amiodarone-d4 HCl

Cat.No: TMID-0069

Cat.No: T71981

Cat.No: T71402

Tauroursodeoxycholic-d4 Acid

Cat.No: TMIJ-0199

Synonym: Tauroursodiol-d4

Tauroursodeoxycholic Acid-d4 Sodium Salt

Cat.No: TMIH-0552

Tauroursodeoxycholic-2,2,3,4,4-d5 Acid

Cat.No: TMIJ-0197

Cat.No: TMID-0254

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