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Cat. No. | Product Name | ||
---|---|---|---|
D7800 | 新颖已知活性库 | 8118 compounds | |
提高成功率:新增8118种已知活性化合物,提高实验成功率。 | |||
L6750 | 活血化瘀中药单体库 | 580 compounds | |
580种来源于常见活血化瘀中药的单体化合物,是药物开发、药理研究等领域的有效工具。 | |||
L9850 | 口服活性化合物库 | 2427 compounds | |
2427 种口服活性化合物独特集合,可用于高通量筛选和高内涵筛选 | |||
L3980 | DNA损伤/修复库Plus | 667 compounds | |
667 种 DNA 损伤/修复靶向、结构新颖的化合物; | |||
L2194 | 抗结直肠癌化合物库 | 1545 compounds | |
1545 种与结直肠癌相关的化合物,可以用于高通量和高内涵筛选; | |||
L7900 | 成骨分子库 | 317 compounds | |
317 种成骨相关的生物活性小分子化合物的特有集合,用于高通量、高内涵筛选; | |||
L4300 | Wnt/Hedgehog/Notch 通路化合物库 | 237 compounds | |
237 个Wnt & Hedgehog & Notch 靶点相关的生物活性小分子化合物的特有集合,用于相关通路的研究及药物的筛选,可用于高通量、高内涵筛选。 | |||
L3500 | 组蛋白修饰化合物库 | 469 compounds | |
469 个组蛋白修饰相关的小分子化合物的特有集合,用于高通量、高内涵筛选; | |||
L2196 | 抗卵巢癌化合物库 | 1867 compounds | |
1867 种与卵巢癌相关的化合物,可以用于抗卵巢癌药物研发和药理研究 | |||
L3400 | 临床期小分子药物库 | 3404 compounds | |
3404 个临床期化合物集合,可用于高通量筛选和高内涵筛选; | |||
L2191 | 抗乳腺癌化合物库 | 1939 compounds | |
1939 种与乳腺癌相关的化合物,可以用于抗乳腺癌药物研发和药理研究; | |||
L4100 | TGF-β/Smad靶点化合物库 | 184 compounds | |
184 个 TGF-β/Smad 靶点相关的小分子化合物的特有集合,用于高通量、高内涵筛选; | |||
L5900 | 血脑屏障通透化合物库 | 509 compounds | |
509 个 CNS-Penetrant 生物活性小分子化合物的特有集合,用于高通量、高内涵筛选; | |||
L4510 | 抗寄生虫库 | 419 compounds | |
419 种具有抗寄生虫活性的小分子化合物; | |||
L3200 | 自噬库 | 1248 compounds | |
1248 种细胞自噬相关的生物活性小分子化合物的特有集合,用于自噬相关的研究,用于高通量、高内涵筛选; | |||
L7700 | 神经再生化合物库 | 524 compounds | |
524 种神经再生相关化合物的独特集合,可用于高通量筛选和高内涵筛选; | |||
L9200 | 药物功能重定位化合物库 | 4630 compounds | |
4630 种全球上市药物和临床药物的独特集合,可用于高通量筛选和高内涵筛选,是老药新用、新的药物靶点筛选和细胞诱导的有效工具。 | |||
L6740 | 抗结直肠癌中药单体化合物库 | 382 compounds | |
382 种抗结直肠癌相关的中药单体集合,是药物开发、药理研究的有效工具; | |||
L7500 | 凝血与抗凝化合物库 | 144 compounds | |
144 个化合物的独特集合,可用于高通量筛选和高内涵筛选; | |||
L2550 | 谷氨酰胺代谢化合物库 | 565 compounds | |
565 种谷氨酰胺代谢相关的分子,可以用于高通量和高内涵筛选; | |||
L5200 | 抗代谢疾病化合物库 | 1544 compounds | |
1544 个代谢疾病相关的生物活性小分子化合物的特有集合,用于高通量、高内涵筛选; | |||
L3100 | 造血毒性小分子库 | 101 compounds | |
101 种生物活性小分子化合物的特有集合,用于高通量、高内涵筛选; | |||
L2193 | 抗肝癌化合物库 | 1787 compounds | |
1787 种与肝癌相关的化合物,可以用于抗肝癌药物研发和药理研究; | |||
L3800 | NF-κB 通路分子库 | 729 compounds | |
729 个 NF-κB 信号通路相关的小分子化合物的特有集合,用于高通量、高内涵筛选; | |||
L8110 | 细胞重编程化合物库 | 1813 compounds | |
1813 种重编程信号通路相关的生物活性小分子化合物的特有集合,可用于高通量、高内涵筛选 | |||
L2130 | 抗癌细胞代谢库 | 1268 compounds | |
1268 种癌细胞代谢相关的生物活性小分子化合物的特有集合,用于肿瘤相关的研究以及抗肿瘤药物的筛选,用于高通量、高内涵筛选; | |||
L2521 | 糖酵解化合物库 | 555 compounds | |
555 种糖酵解相关的活性化合物,可用于高通量和高内涵筛选 | |||
L1510 | 核受体化合物库 | 531 compounds | |
531 个核受体作用化合物的独特集合,可用于高通量筛选和高内涵筛选; | |||
L3900 | DNA 损伤和修复分子库 | 910 compounds | |
910 个与 DNA 损伤和修复紧密相关的化合物集合,是高通量筛选,高内涵筛选的良好载体; | |||
L8500 | HIF-1化合物库 | 1336 compounds | |
1336 个HIF-1相关小分子的独特集合,可用于缺血性疾病、癌症等相关领域的药物开发和药理研究; | |||
L7110 | 抗高血压化合物库 | 678 compounds | |
678 种高血压相关的小分子,用于高通量和高内涵筛选; | |||
L5510 | 肝脏毒性化合物库 | 1001 compounds | |
1001 个肝脏毒性化合物的特有集合,可用于高通量、高内涵筛选,是毒理学研究的良好工具; | |||
L2700 | 肾上腺素能受体化合物库 | 193 compounds | |
193 种特异靶向肾上腺素受体的生物活性小分子化合物的集合,是相关疾病药物筛选的有效工具; | |||
L4700 | 免疫/炎症分子化合物库 | 4720 compounds | |
4720 种具有抗炎症活性的化合物的特有集合,可用于高通量筛选和高内涵筛选; | |||
L8100 | 细胞周期化合物库 | 677 compounds | |
677 种细胞周期相关的生物活性小分子化合物的特有集合,用于高通量、高内涵筛选; | |||
L4600 | 植物来源化合物库 | 3048 compounds | |
3048 个植物来源天然产物的独特集合,来自277类植物的精心之选; | |||
L3700 | JAK-STAT 化合物库 | 252 compounds | |
252 个 JAK/STAT 靶点相关的小分子化合物的独特集合,用于高通量、高内涵筛选; | |||
L4800 | 血管生成库 | 1353 compounds | |
1353 个高潜力的抑制或促进血管生成的小分子集合,可用于药物靶点开发、血管生成机理研究的高通量筛选,高内涵筛选; | |||
L4150 | 新颖已知活性精选库 | 989 compounds | |
989 种百里挑一的活性化合物; | |||
L1120 | AMPK靶向分子库 | 80 compounds | |
80 个靶向AMPK 的分子集合,可用于高通量和高内涵筛选; | |||
L2510 | 脂代谢化合物库 | 492 compounds | |
492 个脂代谢相关的化合物集合,可用于高通量和高内涵筛选; | |||
L2120 | 抗癌临床化合物库 | 2545 compounds | |
2545 个具有抗癌活性小分子的独特集合,可用于高通量高内涵筛选。 | |||
L7000 | 活性脂质化合物库 | 385 compounds | |
385 种生物活性小分子化合物,用于高通量、高内涵筛选; | |||
L5500 | 毒性化合物库 | 262 compounds | |
262 个细胞毒性化合物的特有集合,可用于高通量、高内涵筛选。 | |||
L1520 | 膜蛋白靶向化合物库 | 4175 compounds | |
L8200 | 抗衰老化合物库 | 3279 compounds | |
3279 个抗衰老化合物的独特集合,可用于高通量筛选和高内涵筛选; | |||
L2140 | 癌细胞分化化合物库 | 406 compounds | |
406 个诱导肿瘤细胞分化化合物的独特集合,可用于高通量筛选和高内涵筛选; | |||
L4520 | 抗菌活性库 | 904 compounds | |
904 种具有抗菌活性的化合物,是抗菌药物研发的有力工具; | |||
L9000 | 细胞凋亡化合物库 | 1760 compounds | |
1760 种与凋亡相关的生物活性小分子化合物的特有集合,多用于研究肿瘤发生发展机制和抗癌药物筛选等。可用于高通量筛选和高内涵筛选; | |||
L2192 | 抗胰腺癌化合物库 | 2238 compounds | |
2238 种与胰腺癌相关的化合物,可以用于高通量和高内涵筛选; | |||
L2610 | 神经递质受体化合物库 | 1513 compounds | |
1513 种与神经递质受体相关的化合物,用于高通量、高内涵筛选; | |||
L2530 | 小鼠代谢化合物库 | 218 compounds | |
218 种小鼠代谢化合物的集合,可用于高通量筛选和高内涵筛选; | |||
L2520 | 糖代谢化合物库 | 702 compounds | |
702 种糖代谢相关的化合物,可用于高通量和高内涵筛选; | |||
L2400 | 内分泌激素分子库 | 784 compounds | |
784 种与内分泌系统相关的生物活性小分子化合物的特有集合,用于高通量、高内涵筛选; | |||
L8300 | 染色质修饰分子库 | 250 compounds | |
250 种染色质化学修饰相关的生物活性小分子化合物的特有集合,用于高通量、高内涵筛选; | |||
L2910 | 抗氧化化合物库 | 1314 compounds | |
氧化应激(Oxidative Stress,OS)是指体内氧化与抗氧化作用失衡的一种状态。氧化应激导致活性氧(ROS)大量积累,氧化程度超出抗氧化物的清除能力,从而引起氧化损伤,氧化应激损伤是许多疾病发生的基础,不同程度的氧化应激造成的细胞效应与心脑血管疾病、神经退行性病变、炎症和肿瘤密切相关。抗氧化剂是一类能够对抗氧化应激,降低氧化损伤的一类化合物。 TargetMol 抗氧化化合物库是1314 种对氧化应激具有抑制作用的小分子特有集合,是研究氧化应激的有用工具,可以用于高通量筛选和高内涵筛选。 | |||
L1500 | GPCR靶点分子库 | 1940 compounds | |
1940 种与 G 蛋白及其耦联受体相关的生物活性小分子化合物,所有小分子都具有良好的生物和药理活性,部分是 FDA 批准的上市药物; | |||
L2501 | 人内源代谢化合物库 Plus | 1283 compounds | |
1283种内源性生物活性化合物的独特集合,用于高通量、高内涵筛选。 | |||
L1300 | PI3K/Akt/mTOR 化合物库 | 420 compounds | |
420 种与PI3K/Akt/mTOR 相关的生物活性小分子化合物的特有集合,用于PI3K/Akt/mTOR 相关研究以及高通量、高内涵筛选; | |||
L9830 | 抗帕金森病化合物库 | 857 compounds | |
857 种帕金森病相关的化合物集合,可用于高通量和高内涵筛选; | |||
L2800 | 5-羟色胺分子库 | 268 compounds | |
268 种生物活性小分子化合物,用于高通量、高内涵筛选; | |||
L6210 | 藏药化合物库 | 747 compounds | |
747 种藏药来源的天然产物分子集合,可以用于高通量和高内涵筛选; | |||
L3510 | 甲基化化合物库 | 128 compounds | |
128 种甲基化相关的化合物,可以用于高通量和高内涵筛选; | |||
L9840 | 抗阿尔茨海默症化合物库 | 986 compounds | |
986 种阿尔茨海默症相关的化合物集合,可用于高通量和高内涵筛选; | |||
L6230 | 苗药化合物库 | 534 compounds | |
534种苗族特色药材的天然产物分子,可用于高通量和高内涵筛选 | |||
L8400 | 血液病分子库 | 514 compounds | |
514 种造血系统疾病相关的生物活性小分子化合物的特有集合,用于高通量、高内涵筛选; | |||
L4500 | 抗真菌库 | 252 compounds | |
252 个抗真菌活性化合物的独特集合,包含作用于真菌相关靶点的化合物和临床中用于真菌类疾病的药物,是相关疾病药物筛选的有效工具。 | |||
L1580 | GPCR库Plus | 338 compounds | |
338 种GPCR 靶向、结构新颖的化合物; | |||
L8700 | 铁死亡化合物库 | 779 compounds | |
779 种与铁死亡通路相关的化合物,可用于高通量和高内涵筛选; | |||
L2640 | 神经保护化合物库 | 990 compounds | |
L8200 | 抗衰老化合物库 | 3279 compounds | |
3279 个抗衰老化合物的独特集合,可用于高通量筛选和高内涵筛选; | |||
L2140 | 癌细胞分化化合物库 | 406 compounds | |
406 个诱导肿瘤细胞分化化合物的独特集合,可用于高通量筛选和高内涵筛选; | |||
L4520 | 抗菌活性库 | 904 compounds | |
904 种具有抗菌活性的化合物,是抗菌药物研发的有力工具; | |||
L9000 | 细胞凋亡化合物库 | 1760 compounds | |
1760 种与凋亡相关的生物活性小分子化合物的特有集合,多用于研究肿瘤发生发展机制和抗癌药物筛选等。可用于高通量筛选和高内涵筛选; | |||
L2192 | 抗胰腺癌化合物库 | 2238 compounds | |
2238 种与胰腺癌相关的化合物,可以用于高通量和高内涵筛选; | |||
L1310 | 细胞骨架化合物库 | 759 compounds | |
759 种细胞骨架相关的化合物,可以用于高通量和高内涵筛选; | |||
L4900 | 心血管毒性化合物库 | 131 compounds | |
131 种心血管毒性化合物的独特集合,可用于毒理学研究; | |||
L5300 | 线粒体靶向库 | 812 compounds | |
812 种具有潜在或确定线粒体靶向活性的化合物,以促进针对线粒体的药物研究; | |||
L8000 | 干细胞分化化合物库 | 1197 compounds | |
1197 种干细胞分化信号通路相关的生物活性小分子化合物的特有集合,可用于高通量、高内涵筛选; | |||
L2195 | 抗前列腺癌化合物库 | 2070 compounds | |
2070 种与前列腺癌相关的化合物,可以用于高通量和高内涵筛选 | |||
L2630 | 神经元分化化合物库 | 672 compounds | |
672 种与神经元分化相关的化合物,可以用于神经系统疾病药物研发 | |||
L1800 | 抗感染化合物库 | 2938 compounds | |
2938 种具有抗感染活性的化合物的特有集合,包括抗细菌、抗真菌、抗巨细胞病毒、抗HIV、抗SARS、抗流感等活性; | |||
L7100 | 抗肥胖化合物库 | 2247 compounds | |
2247 个抗肥胖化合物的独特集合,可用于高通量筛选和高内涵筛选; | |||
L9300 | 大环化合物库 | 210 compounds | |
210 种活性已知的大环化合物,用于高通量、高内涵筛选; | |||
L2100 | 抗癌化合物库 | 7234 compounds | |
7234 种肿瘤相关的生物活性小分子化合物的特有集合,用于高通量、高内涵筛选; | |||
L9700 | 内质网应激化合物库 | 193 compounds | |
193 个内质网应激相关的化合物集合,可用于高通量和高内涵筛选; | |||
L1110 | 微管靶向化合物库 | 142 compounds | |
142 种靶向微管的分子集合,用于高通量筛选和高内涵筛选; | |||
L6710 | 中药抗炎分子库 | 1246 compounds | |
1246 种具有抗炎活性或靶向炎症相关靶点的中药单体集合,是药物开发、药理研究的有效工具; | |||
L7200 | 钙通道分子库 | 140 compounds | |
140 种钙通道相关化合物的独特集合,可用于高通量筛选和高内涵筛选; | |||
L2900 | 氧化还原化合物库 | 1264 compounds | |
1264 个活性化合物,已经验证具有一定的抗氧化活性,包括 ROS 清除剂、iNOS、eNOS、及抗氧化的天然产物,是研究疾病机理以及药物研究的优良载体 | |||
L4020 | NO PAINS 化合物库 | 9384 compounds | |
TargetMol NO PAINS 化合物库包含 9384 个剔除了PAINS 的小分子活性化合物,可用于新药研发,信号通路研究,老药新用等研究。 | |||
L6300 | 药食同源库 | 1290 compounds | |
1290 个药食同源化合物的独特集合,可用于高通量筛选和高内涵筛选; | |||
L4000 | 经典已知活性库 | 14439 compounds | |
14439 个已知活性化合物的集合,可用于高通量筛选、高内涵筛选、细胞诱导和靶点确认; | |||
L9240 | 农药化合物库 | 270 compounds | |
270种农药相关化合物的独特集合,可用于高通量筛选和高内涵筛选; | |||
L9910 | 化妆品原料化合物库 | 800 compounds | |
L8600 | 泛素化化合物库 | 210 compounds | |
210 种泛素化相关的小分子,用于高通量和高内涵筛选; | |||
L1710 | 抗COVID-19化合物库 | 1133 compounds | |
1133 种对SARS-CoV-2有抑制作用或潜在抑制作用的化合物集合,可用于高通量和高内涵筛选; | |||
L2170 | 肿瘤免疫治疗小分子化合物库 | 449 compounds | |
449 种靶向肿瘤免疫治疗靶点的小分子,可用于高通量和高内涵筛选,是研究肿瘤免疫治疗的有力工具; | |||
L6220 | 蒙药化合物库 | 950 compounds | |
950 种蒙药来源的天然产物分子集合,可以用于高通量和高内涵筛选; | |||
L1720 | 核苷类化合物库 | 334 compounds | |
334 种核苷类化合物,包括核苷酸、核苷酸类似物及衍生物等,适用于抗病毒、抗肿瘤、抗真菌、抗抑郁等药物的研发; | |||
L1700 | 抗病毒库 | 1040 compounds | |
1040 种具有抗病毒活性的化合物的特有集合,是筛选新型抗病毒药的有效工具;可用于高通量筛选和高内涵筛选; | |||
L1720 | 核苷类化合物库 | 334 compounds | |
334 种核苷类化合物,包括核苷酸、核苷酸类似物及衍生物等,适用于抗病毒、抗肿瘤、抗真菌、抗抑郁等药物的研发; | |||
L1380 | 转录因子库 | 695 compounds | |
695 种转录因子靶向、结构新颖的化合物; | |||
L2180 | 抗肿瘤库Plus | 1468 compounds | |
1468 种抗肿瘤相关、结构新颖的化合物; | |||
L2190 | 抗肺癌化合物库 | 1702 compounds | |
1702 种与肺癌相关的化合物,可以用于抗肺癌药物研发和药理研究; | |||
L4010 | 已知活性化合物库 | 22555 compounds | |
22555 个已知活性化合物的集合,可用于高通量筛选、高内涵筛选、细胞诱导和靶点确认; | |||
L9810 | 抗纤维化化合物库 | 1180 compounds | |
1180 种潜在的抗纤维化分子,是研究纤维化的有效工具,可以用于高通量筛选和高内涵筛选; | |||
L9420 | 外泌体相关化合物库 | 76 compounds | |
76 种外泌体相关的化合物,可以用于高通量和高内涵筛选; | |||
L6720 | 抗COVID-19中药单体库 | 1147 compounds | |
根据抗新冠肺炎疫情过程中应用于临床治疗的中药方剂,收集了1147 种相关中药来源的单体化合物,可用于高通量和高内涵筛选,是抗新冠病毒药物研发的良好工具; | |||
L8720 | 细胞焦亡化合物库 | 1066 compounds | |
1066 种细胞焦亡相关的化合物,可以用于细胞焦亡相关研究。 | |||
L3300 | 组胺&褪黑色素化合物库 | 153 compounds | |
153 种生物活性小分子化合物,用于高通量、高内涵筛选; | |||
L2560 | 代谢化合物库 | 2320 compounds | |
2320 种代谢途径相关的化合物,可用于高通量和高内涵筛选。 | |||
L9600 | 多肽分子库 | 791 compounds | |
791 种多肽类分子,可用于多肽药物开发及信号转导通路和作用机制研究; | |||
L2600 | 神经信号分子库 | 2540 compounds | |
2540 种CNS 相关的生物活性小分子化合物的特有集合,用于高通量、高内涵筛选; | |||
L9860 | 抗抑郁症化合物库 | 1163 compounds | |
1163 种与抑郁症相关的化合物,可以用于高通量和高内涵筛选 | |||
L2160 | 抗癌活性化合物库 | 3188 compounds | |
3188 种具有抗肿瘤活性的化合物的特有集合,用于高通量、高内涵筛选; | |||
L2620 | 神经退行性疾病化合物库 | 2154 compounds | |
2154 种与神经退行性疾病相关的化合物,可用于高通量和高内涵筛选; | |||
L1200 | 表观遗传库 | 953 compounds | |
953 种表观遗传学研究相关的生物活性小分子的特有集合,用于表观遗传学研究及其相关的检测和高通量、高内涵筛选; | |||
L6170 | 风味化合物库 | 420 compounds | |
L2690 | 疼痛相关化合物库 | 2739 compounds | |
2739种疼痛相关化合物的独特集合,可用于高通量筛选和高内涵筛选 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T76788 |
Demcizumab
OMP 21M18 |
Gamma-secretase | Neuroscience; Proteases/Proteasome; Stem Cells |
Demcizumab (OMP 21M18) 是一种抗 DLL4 单克隆抗体。Demcizumab 是一种有效的 Notch 通路抑制剂。Demcizumab 在多种癌症模型中无论使单独还联合化疗试剂使用都是有效的。 | |||
T77750 |
Rosmantuzumab
OMP-131R10 |
Others | Others |
Rosmantuzumab (OMP-131R10) 是一种 人源化抗 R-spondin 3 (RSPO3)单克隆抗体。Rosmantuzumab 具有潜在的抗肿瘤活性,可用于研究晚期复发难治性实体瘤。 | |||
T77450 |
Vantictumab
OMP-18R5 |
||
Vantictumab (OMP-18R5)为全人源IgG2单克隆抗体,针对FZD1/2/5/7/8受体抑制Wnt信号通路。该抗体适用于研究治疗转移性HER2阴性乳腺癌及转移性胰腺腺癌。 | |||
T82502 |
Efaprinermin alfa
OMP-336B11 |
||
Efaprinermin alfa (OMP-336B11),一种人源化单克隆抗体,靶向TNFRSF18。该化合物为GITR配体-Fc融合蛋白。 | |||
T82436 |
Etigilimab
OMP-313M32 |
||
Etigilimab (OMP-313M32) 为人源化IgG1单克隆抗体,旨在阻断TIGIT与PVR (CD155;脊髓灰质炎病毒受体)间的结合,进而抑制信号传导,通过诱导靶细胞凋亡实现其作用。 | |||
TP2180L |
Compstatin control peptide acetate
|
Complement System | Immunology/Inflammation |
Compstatin control peptide acetate 是补体蛋白 C3 的抑制剂,通过结合和抑制补体 C3 的切割。 | |||
T0550 |
Domperidone EP Impurity A
5-氯-1,3-二氢-1-(4-哌啶基)-2H-苯并咪唑-2-酮 |
Others | Others |
Domperidone EP Impurity A 用作医药中间体。 | |||
T0205 |
Brompheniramine maleate
Dimotane,马来酸溴苯那敏,Rolabromophen,Brompheniramine hydrogen maleate,Dimetane |
5-HT Receptor; Histamine Receptor | GPCR/G Protein; Immunology/Inflammation; Neuroscience |
Brompheniramine maleate (Dimotane) 是一种可口服的丙胺类抗组胺剂,具有抗胆碱能和抗抑郁作用,可用于过敏性鼻炎和缓解疼痛的研究。它是一种选择性组胺 H1 受体拮抗剂,Kd 为 6.06 nM。 | |||
T38332 |
Complement factor D-IN-2
|
Complement System | Immunology/Inflammation |
Complement factor D-IN-2 是 omplement factor D 的有效抑制剂,在替代补体途径的早期和关键时刻靶向 factor D 并抑制补体级联反应。Complement factor D-IN-2在自身免疫疾病的方面有研究的价值。 | |||
T131732 |
Compound AC-542/20643006
|
Others | Others |
Compound AC-542/20643006 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T131732。 | |||
T121064 |
Compound N039-0043
|
Others | Others |
Geminin, Potency: 290.9 nM | |||
T131305 |
Compound N027-0014
|
Others | Others |
Compound N027-0014 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T131305。 | |||
T131725 |
Compound TCFN92660
|
Others | Others |
Compound TCFN92660 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T131725,CAS号为 56070-89-4。 | |||
T98006 |
Compound F0415-0075
|
Others | Others |
Compound F0415-0075 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T98006,CAS号为 2051-07-2。 | |||
TPL0053 |
Compound 227105-11-5
|
Others | Others |
Compound 227105-11-5 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 TPL0053,CAS号为 227105-11-5。 | |||
T9241 |
o-Cresolphthalein Complexone
|
Others | Others |
o-Cresolphthalein Complexone 是一种金属络合指示剂和酸碱指示剂。 | |||
T95359 |
Compound F0433-0067
|
Others | Others |
hiCE inhibitor-1是一种磺胺衍生物,是一种选择性的人体肠道酶 (hiCE) 抑制剂,Ki 值为 53.3 nM。hiCE inhibitor-1可用于改善 Irinotecan 引起的腹泻。 | |||
T0535 |
Memantine Related Compound B
美金刚杂质B,3,5-Dimethyl-1-adamantanol |
Others | Others |
Memantine Related Compound B (3,5-Dimethyl-1-adamantanol) 是Memantine 的杂质。 | |||
T13572 |
Cancer-Targeting Compound 1
|
Others | Others |
Cancer-Targeting Compound 1可用于激素相关癌症的研究,包括治疗或预防肌瘤、子宫平滑肌瘤、多囊卵巢综合征或激素依赖性癌等等。 | |||
T3586 |
Compound 401
2-morpholino-4H-pyrimido[2,1-a]isoquinolin-4-one |
DNA-PK | DNA Damage/DNA Repair; PI3K/Akt/mTOR signaling |
Compound 401 (2-morpholino-4H-pyrimido[2,1-a]isoquinolin-4-one) 是一种可靶向 mTOR 的合成 DNA-PK 抑制剂,IC50为0.28 μM。 | |||
T9853 |
STING activator Compound 53
|
STING | Immunology/Inflammation |
基于 oxindole 核心结构的 STING activator Compound 53 在永生化细胞和原代细胞中表现出强大的 STING(人 EC50 185 nM)的靶向功能激活以及与 STING 激活一致的细胞因子诱导指纹。 | |||
T21769L |
β-Pompilidotoxin Acetate
β-Pompilidotoxin Acetate(216064-36-7 Free base) |
Sodium Channel | Membrane transporter/Ion channel |
β-Pompilidotoxin Acetate 是一种黄蜂毒肽。 它可以减缓钠通道的失活并增加细胞中的稳态钠电流。 | |||
T12262L1 |
NPS ALX Compound 4a hydrochloride(1:1)
|
5-HT Receptor | GPCR/G Protein; Neuroscience |
NPS ALX Compound 4a hydrochloride(1:1)是一种有效、选择性的 5-羟色胺受体 6 (5-HT6) 受体拮抗剂,IC50 值为 7.2 nM,且具有高亲和力,Ki 值为 0.2 nM。 | |||
T9184L |
Compound 3344 hydrochloride
Compound 3344 hydrochloride (2368246-78-8 free base) |
Ras | GPCR/G Protein; MAPK |
Compound 3344 hydrochloride 是 KRAS 效应相互作用的抑制剂,亲和力为 126nm。 | |||
T91266 |
Compound F0401-0089
|
Others | Others |
Compound F0401-0089 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T91266,CAS号为 5468-37-1。 | |||
Fr14571 |
Compound AR0033QU
|
Others | Others |
Compound AR0033QU 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 Fr14571,CAS号为 21436-98-6。 | |||
T131269 |
Compound N039-0033
|
Others | Others |
Compound N039-0033 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T131269。 | |||
T131226 |
Compound N058-0062
|
Others | Others |
Compound N058-0062 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T131226。 | |||
T131284 |
Compound N038-0008
|
Others | Others |
Compound N038-0008 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T131284。 | |||
T50125 |
Compound C749
|
Others | Others |
Compound C749 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T50125,CAS号为 57-03-4。 | |||
T131363 |
Compound N011-0459
|
Others | Others |
Compound N011-0459 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T131363。 | |||
T131633 |
Compound 1554-0035
|
Others | Others |
Compound 1554-0035 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T131633。 | |||
T0547 |
FlutaMide Related CoMpound B
|
Others | Others |
FlutaMide Related CoMpound B 用作医药中间体。 | |||
T9544 |
Compound 1T-0216
|
Others | Others |
Compound 1T-0216 是AKT1-FAK 相互作用的阻滞剂,在不影响基础FAK 磷酸化的情况下,减少对人类SW620结肠癌细胞细胞外压力的FAK 磷酸化的刺激。 | |||
T19963 |
Alizarin Complexone
Alizarin Fluorine Blue,Alizarin-3-methyliminodiacetic acid,茜素络合指示剂 |
Reverse Transcriptase | Microbiology/Virology |
Alizarin Complexone (Alizarin-3-methyliminodiacetic acid) 是 Rous 相关病毒 2 逆转录酶的抑制剂。 Alizarin Complexone 可用作生物研究的钙示踪剂和螯合剂。 | |||
T60198 |
Compound STK672155
|
Others | Others |
Compound STK672155 可用于化学和生命科学领域的研究。 | |||
T0082 |
Domperidone
R33812,多潘立酮 |
Dopamine Receptor | GPCR/G Protein; Neuroscience |
Domperidone (R33812) 是多巴胺 2 受体拮抗剂,能够影响胃和小肠的化学感受器触发区和运动功能,具有止吐和促动力作用。 | |||
T72082 |
Compound T72082(SC)
|
ROS | Immunology/Inflammation |
ROS-IN-1 是线粒体 ROS 抑制剂,可用于减轻氧化应激或抑制活性氧 (ROS) 的产生。 | |||
T13623 |
Compound 48/80 trihydrochloride
C48/80 trihydrochloride |
Phospholipase | Metabolism |
Compound 48/80 trihydrochloride (C48/80 trihydrochloride) 是 N-甲基对甲氧基苯乙胺和甲醛发生缩合反应后的混合物。Compound 48/80 trihydrochloride 是一种肥大细胞 (mast cell) 脱颗粒剂和组胺 (histamine) 释放剂。Compound 48/80 trihydrochloride 对人血小板磷脂酰肌醇特异性磷脂酶 C (phosphatidylinositol-specific phospholipase C) 活性有抑制作用。 | |||
T7944 |
VPS34 inhibitor 1 (Compound 19, PIK-III analogue)
PIK-III analogue |
PI3K | PI3K/Akt/mTOR signaling |
VPS34 inhibitor 1 (Compound 19, PIK-III analogue) (PIK-III analogue) 是一种有效的选择性 VPS34抑制剂( IC50 : 15 nM)。 | |||
T67779 |
Compound TPX-0046
|
c-RET | Apoptosis; Tyrosine Kinase/Adaptors |
Compound TPX-0046 是有效的RET 的抑制剂。化合物TPX-046可以抑制RET 的自磷酸化。 | |||
T67774 |
Compound CDy9
|
Carbonic Anhydrase | Metabolism |
Compound CDy9 是碳酸酐酶(CA)的高选择性抑制剂,对hCA II 的IC50值为0.18μM。 | |||
T38387 |
Compound C108
|
GTPase | GPCR/G Protein |
Compound C108 是 GTPase 激活蛋白 SH3 结构域结合蛋白 2 (G3BP2) 的抑制剂。 Compound C108可用于乳腺肿瘤和食管鳞状细胞癌的研究。 | |||
TP1304 |
Compstatin
坎普他汀 |
Complement System | Immunology/Inflammation |
Compstatin 是一种环状十三肽,是补体系统 C3的特异性抑制剂。它只抑制灵长类补体系统的激活,可结合到狒狒的 C3,并对狒狒血液中的蛋白水解裂解具有抗性。它对补体经典途径和旁路途径的 IC50值分别为 63 和 12 μM。 | |||
T10863 |
Complement C5-IN-1
|
Complement System | Immunology/Inflammation |
Complement C5-IN-1 (Compound 7) 是补体成分蛋白5 (C5) 的小分子抑制剂。 Complement C5-IN-1 与 C5 相互作用以防止其被 C5 转化酶切割, 阻断酵母多糖诱导的 50%人全血 MAC 沉积的 IC50 值为 0.77 μM。 | |||
T131283 |
Compound N038-0206
|
Others | Others |
Compound N038-0206 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T131283。 | |||
T131323 |
Compound N017-0016
|
Others | Others |
Compound N017-0016 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T131323。 | |||
T131321 |
Compound N017-0020
|
Others | Others |
Compound N017-0020 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T131321。 | |||
T131727 |
Compound AK-693/40962731
|
Others | Others |
Compound AK-693/40962731 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T131727。 | |||
T131278 |
Compound N039-0003
|
Others | Others |
Compound N039-0003 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T131278。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TC0036 |
Compound Lup-20(29)-en-3-yl acetate
|
IL Receptor; VEGFR; Others; TNF; COX | Angiogenesis; Apoptosis; Immunology/Inflammation; Neuroscience; Others; Tyrosine Kinase/Adaptors |
Lup-20(29)-en-3-yl acetate 是 Lupeol 的衍生物,通过下调 TNF-α、IL-1β、MCP-1、COX-2、VEGF 和颗粒酶 B 来抑制类风湿性关节炎的进展。 | |||
TPL0186 |
Compound 1769-24-0
|
Others | Others |
Compound 1769-24-0 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TPL0186,CAS号为 1769-24-0。 | |||
T4130 |
Complanatuside
沙苑子苷,Complanatoside |
Others | Others |
Complanatuside (Complanatoside) 是一种黄酮类化合物,存在于中药沙苑子中。 | |||
TN1582 |
Compound TN1582(SC)
|
Antiviral | Immunology/Inflammation |
Dihydromollugin 是在 Rubia cordifolia 中发现的萘甲酸酯,可能具有抗肿瘤、抑制病毒和其他活性。 | |||
TN1259 |
Complanatoside B
3-O-Β-D-芹糖(1-2)-Β-D-葡萄糖-鼠李柠檬素4'-O-Β-D-葡萄糖苷,沙苑子苷B |
Others | Others |
Complanatoside B 是一种黄酮类化合物,具有抗炎作用。 | |||
T11287 |
Filipin complex
|
Antifungal | Microbiology/Virology |
Filipin complex 是一种 28 元环戊烯大环内酯类抗真菌抗生素,由 S. filipinensis、S. avermitilis 和 S. miharaensis 产生的混合物,抑制 PRRSV 病毒进入细胞,通过与膜固醇相互作用发挥作用。 | |||
T3922 |
Complanatoside A
沙苑子苷A,沙苑子苷 A |
Others | Others |
Complanatoside A 是一种黄酮醇糖苷,分离自黄芪,目前是2010版中国药典A. complanatus 的质量控制指数。 | |||
TN6504 |
Complanatoside C
|
||
Complanatoside C 是分离自黄芪的一种黄酮苷。 | |||
TN6407 |
New compound 5
|
||
New compound 5是一种天然产物,属于五味子科五味子属,其产品编号为 TN6407。New compound 5可用作对照参考。 | |||
T19204 | Compound 2 | Others | Others |
Compound 2 is used for the research of metabolic bone diseases. | |||
T82691 |
Complanatin
|
||
Complanatin,一种从黄芪中分离得到的酰基化黄酮醇苷。 | |||
T82738 |
Chisocheton compound F
|
||
Chisocheton compound F,一种从Melia toosendan茎皮中分离的天然产物。 | |||
TN6550 |
New compound 2
|
||
New compound 2 可用于生命科学领域的相关研究,其产品编号为 TN6550。 | |||
TN6434 |
New compound 4
|
||
New compound 4是一种天然产物,属于豆科葛属,其产品编号为 TN6434。New compound 4可用作对照参考。 | |||
T36990 |
Moenomycin Complex
|
Others | Others |
Moenomycin complex is a mixture of moenomycins A, A12, C1, C3 and C4, which are antibiotics isolated from several strains of Streptomyces that directly inhibit bacterial peptidoglycan glycosyltransferases. [1] The minimal inhibitory concentration of moenomycin A against various Gram-positive bacteria ranges from 1-100 nM.[1] | |||
TN6408 |
New compound 6
|
||
New compound 6是一种天然产物,属于五味子科五味子属,其产品编号为 TN6408。New compound 6可用作对照参考。 | |||
T11202 |
Enniatin complex
|
Others | Others |
Enniatin complex, a mixture of cyclohexadepsipeptides predominantly derived from various Fusarium species of fungi, exhibits inhibitory effects on enzymes such as acyl-CoA: cholesterol acyl transferase. Furthermore, it has demonstrated the ability to induce apoptosis in multiple cancer cell lines. In addition to these activities, the Enniatin complex possesses ionophoric, antibiotic, and in vitro hypolipidemic properties. | |||
T82690 |
Complanatin I
|
||
Complanatin I, 一种从Astragalus complanatus中分离出的天然产品,具有特定的化学特性。 | |||
TN6649 |
5'''-O-Feruloyl complanatoside B
|
||
5'''-O-Feruloyl complanatoside B 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6649,CAS号为 142473-98-1。 | |||
TN6410 |
New compound 3
|
||
New compound 3 可用于生命科学领域的相关研究,其产品编号为 TN6410。 | |||
T71896 |
Brevicompanine B
|
Others | Others |
Brevicompanine B is a fungal metabolite that has plant growth and circadian rhythm regulatory activity. Brevicompanine B inhibits primary root growth in Arabidopsis seedlings and disrupts the transcription of various genes involved in the regulation of plant circadian rhythm. It is active against P. falciparum. |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-00485 |
Olfactory Marker Protein Protein, Human, Recombinant (His)
OMP,olfactory marker protein |
Human | E. coli |
OMP (Olfactory Marker Protein) is a Protein Coding gene. OMP is a protein expressed in the mature olfactory and vomeronasal neurons of many vertebrates, such as mammals, amphibians, and bony fishes. Its structure and protein sequence are highly conserved between the mouse, rat, and human. OMP is a ubiquitous, cytoplasmic protein found in mature olfactory receptor neurons of all vertebrates. It participates in the olfactory signal transduction pathway. OMP expression is a hallmark of mature verte... | |||
TMPH-00018 |
29 kDa outer membrane Protein, Acinetobacter baumannii, Recombinant (His & Myc & SUMO)
29 kDa OMP |
Acinetobacter baumannii | E. coli |
May be involved in transporting molecules across the outer membrane. | |||
TMPH-00782 |
OMP P5 Protein, Haemophilus influenzae, Recombinant (His & Myc & SUMO)
Outer membrane porin A,Outer membrane protein P5,Outer membr... |
Haemophilus influenzae | E. coli |
Acts as a fimbriae subunit, allowing adhesion to host cells.; With TolR probably plays a role in maintaining the position of the peptidoglycan cell wall in the periplasm. Acts as a porin with low permeability that allows slow penetration of small solutes; an internal gate slows down solute passage. | |||
TMPH-00389 |
OmcB Protein, Chlamydia trachomatis, Recombinant (His & SUMO)
Large cysteine-rich periplasmic protein OmcB,Cysteine-rich o... |
Chlamydia trachomatis | E. coli |
In elementary bodies (EBs, the infectious stage, which is able to survive outside the host cell) provides the structural integrity of the outer envelope through disulfide cross-links with the small cysteine-rich protein and the major outer membrane protein. It has been described in publications as the Sarkosyl-insoluble COMC (Chlamydia outer membrane complex), and serves as the functional equivalent of peptidoglycan. OmcB Protein, Chlamydia trachomatis, Recombinant (His & SUMO) is expressed in E... | |||
TMPH-00022 |
Outer membrane protein Omp38, Acinetobacter baumannii, Recombinant (His & SUMO)
omp38,Outer membrane protein Omp38 |
Acinetobacter baumannii | E. coli |
Porin. Induces apoptosis in human cells through caspases-dependent and AIF-dependent pathways. Purified Omp38 enters the cells and localizes to the mitochondria, which leads to a release of proapoptotic molecules such as cytochrome c and AIF (apoptosis-inducing factor). Outer membrane protein Omp38, Acinetobacter baumannii, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 52.5 kDa and the accession number is A3M8K2. | |||
TMPH-00021 |
Outer membrane protein Omp38, Acinetobacter baumannii, Recombinant (His)
omp38,Outer membrane protein Omp38 |
Acinetobacter baumannii | P. pastoris (Yeast) |
Porin. Induces apoptosis in human cells through caspases-dependent and AIF-dependent pathways. Purified Omp38 enters the cells and localizes to the mitochondria, which leads to a release of proapoptotic molecules such as cytochrome c and AIF (apoptosis-inducing factor). | |||
TMPH-00023 |
Outer membrane protein Omp38, Acinetobacter baumannii, Recombinant (His & Myc)
Outer membrane protein Omp38,Outer membrane protein... |
Acinetobacter baumannii | E. coli |
Functions as a porin. Induces apoptosis in human cell lines through caspase-dependent and AIF-dependent pathways. Purified Omp38 enters host cell and localizes to the mitochondria, which presumably leads to a release of proapoptotic molecules such as cytochrome c and AIF (apoptosis-inducing factor). Binds peptidoglycan, contributes to cell wall maintenance (Probable). Outer membrane protein Omp38, Acinetobacter baumannii, Recombinant (His & Myc) is expressed in E. coli expression system with N-1... | |||
TMPY-00686 |
Complement C2 Protein, Human, Recombinant (His)
CO2,complement component 2,ARMD14 |
Human | HEK293 Cells |
Complement C2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 82.5 kDa and the accession number is P06681-1. | |||
TMPY-05732 |
Complement C3 Protein, Cynomolgus, Recombinant (His)
complement component 3 |
Cynomolgus | HEK293 Cells |
Complement C3 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 186.40 kDa and the accession number is XP_005587776.1. | |||
TMPY-05057 |
Complement C5 Protein, Human, Recombinant (His & FLAG)
C5b,ECLZB,C5a,CPAMD4,C5D,complement compon... |
Human | HEK293 Cells |
Complement C5 Protein, Human, Recombinant (His & FLAG) is expressed in HEK293 mammalian cells with His and Flag tag. The predicted molecular weight is 188.8 kDa and the accession number is P01031. | |||
TMPY-04921 |
Complement factor B/CFB Protein, Human, Recombinant (His)
ARMD14,GBG,AHUS4,PBF2,complement factor B,FBI12,BF,... |
Human | HEK293 Cells |
Complement factor B/CFB Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 84.5 kDa and the accession number is AAH04143.1. | |||
TMPY-05731 |
Complement C3 Protein, Human, Recombinant (His)
HEL-S-62p,CPAMD1,ARMD9,C3b,ASP,C3a,AHUS5,complement... |
Human | HEK293 Cells |
Complement C3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 186.43 kDa and the accession number is P01024. | |||
TMPY-00653 |
Complement C5 Protein, Human, Recombinant (Complement C5a)
C5D,C5b,CPAMD4,complement component 5,C |
Human | E. coli |
Complement C5 Protein, Human, Recombinant (Complement C5a) is expressed in E. coli expression system. The predicted molecular weight is 8.3 kDa and the accession number is P01031. | |||
TMPY-03012 |
Complement C7 Protein, Human, Recombinant (hFc)
complement component 7,Complement... |
Human | HEK293 Cells |
Complement C7 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 118 kDa and the accession number is P10643. | |||
TMPY-00687 |
Complement C2 Protein, Human, Recombinant (hFc)
ARMD14,complement component 2,CO2 |
Human | HEK293 Cells |
Complement C2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 110 kDa and the accession number is P06681-1. | |||
TMPY-00359 |
C1s-A subcomponent Protein, Mouse, Recombinant (His)
C1s,MGC13283,AI255193,C1sa,AA959438,AI327365 |
Mouse | HEK293 Cells |
C1s-A subcomponent Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 76.6 kDa and the accession number is AAH18319.1. | |||
TMPY-05459 |
Complement C5a Protein, Mouse, Recombinant, Biotinylated
complement component 5 |
Mouse | E. coli |
Complement C5a Protein, Mouse, Recombinant, Biotinylated is expressed in E. coli expression system. The predicted molecular weight is 9 kDa and the accession number is P06684. | |||
TMPY-05325 |
Exosome Component 9/EXOSC9 Protein, Human, Recombinant (His)
exosome component 9,p5,p6,PMSCL1,Rrp45p,RRP45,PM/Sc... |
Human | Baculovirus Insect Cells |
Exosome Component 9/EXOSC9 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 51.3 kDa and the accession number is Q06265-1. | |||
TMPK-00151 |
Complement Factor D/CFD Protein, Mouse, Recombinant (hFc)
C3 convertase activator,AMBP-1,PFD,FACTOR D,CFD,ADN,EC 3.4.2... |
Mouse | HEK293 Cells |
Complement factor D is a serine protease essential for the activation of the alternative pathway and is expressed in the kidney, adipocytes, and macrophages. Factor D is found at relatively high levels in glomeruli suggesting that this component of the complement cascade could influence renal pathophysiology.Complement factor D or alternative pathway activation is needed to prevent spontaneous accumulation of C3 and IgM deposits within the mesangium. Complement Factor D/CFD Protein, Mouse, Recom... | |||
TMPH-01132 |
Complement C8a Protein, Human, Recombinant (His)
C8A,Complement component 8 subunit alpha,C... |
Human | E. coli |
Complement C8a Protein, Human, Recombinant (His) is expressed in E. coli. | |||
TMPH-01133 |
Complement C8b Protein, Human, Recombinant (His)
Complement component C8 beta chain,C8B,C |
Human | E. coli |
Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. Complement C8b Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 67.0 kDa and the accession number is P07358. | |||
TMPY-01041 |
Compound TMPY-01041
|
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TMPH-02604 |
Complement C3 Protein, Mouse, Recombinant (His & SUMO)
C3,Complement C3 |
Mouse | E. coli |
Complement C3 Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 55.3 kDa and the accession number is P01027. | |||
TMPH-01131 |
Complement C4-B Protein, Human, Recombinant (His & SUMO)
C4B,C3 and PZP-like alpha-2-macroglobulin domain-containing ... |
Human | E. coli |
Complement C4-B Protein, Human, Recombinant (His & SUMO) is expressed in E. coli. | |||
TMPY-04902 |
Complement C5a Protein, Mouse, Recombinant
complement component 5 |
Mouse | E. coli |
Complement C5a Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 9 kDa and the accession number is P06684. | |||
TMPH-03107 |
Complement C5a Protein, Pig, Recombinant (His)
Complement C5a anaphylatoxin,C5 |
Sus scrofa (Pig) | P. pastoris (Yeast) |
Derived from proteolytic degradation of complement C5, C5a anaphylatoxin is a mediator of local inflammatory process. Binding to the receptor C5AR1 induces a variety of responses including intracellular calcium release, contraction of smooth muscle, increased vascular permeability, and histamine release from mast cells and basophilic leukocytes. C5a is also a potent chemokine which stimulates the locomotion of polymorphonuclear leukocytes and directs their migration toward sites of inflammation.... | |||
TMPH-02607 |
Complement factor B Protein, Mouse, Recombinant (His)
C3/C5 convertase,Complement factor B,Cfb,Bf,H2-Bf |
Mouse | E. coli |
Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase. | |||
TMPH-03476 |
OmpD Protein, Salmonella typhimurium, Recombinant (His & SUMO)
Outer membrane porin protein OmpD,ompD |
Salmonella typhimurium | E. coli |
Forms pores that allow passive diffusion of small molecules across the outer membrane. OmpD Protein, Salmonella typhimurium, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 53.6 kDa and the accession number is P37592. | |||
TMPH-00695 |
OmpC Protein, E. coli, Recombinant (His)
Outer membrane protein C,ompC,Outer membrane porin ... |
E. coli | E. coli |
Forms pores that allow passive diffusion of small molecules across the outer membrane.; (Microbial infection) Supports colicin E5 entry in the absence of its major receptor OmpF.; (Microbial infection) A mixed OmpC-OmpF heterotrimer is the outer membrane receptor for toxin CdiA-EC536; polymorphisms in extracellular loops 4 and 5 of OmpC confer susceptibility to CdiA-EC536-mediated toxicity. | |||
TMPH-00697 |
OmpF Protein, E. coli, Recombinant (His & Myc)
Outer membrane protein F,Outer membrane porin F,Porin Om... |
E. coli | E. coli |
Forms pores that allow passive diffusion of small molecules across the outer membrane.; (Microbial infection) It is also a receptor for the bacteriophage T2. Is the major receptor for colicin E5.; (Microbial infection) A mixed OmpC-OmpF heterotrimer is the outer membrane receptor for toxin CdiA-EC536; polymorphisms in extracellular loops 4 and 5 of OmpC confer susceptibility to CdiA-EC536-mediated toxicity. | |||
TMPY-06137 |
Complement C5 Protein, Cynomolgus, Recombinant (His)
complement component 5 |
Cynomolgus | HEK293 Cells |
Complement C5 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 188.1 kDa and the accession number is XP_005580972.1. | |||
TMPY-04129 |
Complement factor H/CFH Protein, Mouse, Recombinant (His)
Sas-1,Mud-1,NOM,complement factor H,Sas1 |
Mouse | HEK293 Cells |
Complement factor H/CFH Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 43.8 kDa and the accession number is E9Q8I0. | |||
TMPY-02641 |
Complement C6 Protein, Human, Recombinant (His)
complement component 6 |
Human | HEK293 Cells |
Complement C6 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 104 kDa and the accession number is AAA59668.1. | |||
TMPK-00671 |
Complement Factor D/CFD Protein, Rhesus macaque, Recombinant (His)
Adipsin,CFD,ADN,Complement factor D,DF,AMBP-1,EC 3.... |
Rhesus | HEK293 Cells |
Complement factor D is a serine protease essential for the activation of the alternative pathway and is expressed in the kidney, adipocytes, and macrophages. Factor D is found at relatively high levels in glomeruli suggesting that this component of the complement cascade could influence renal pathophysiology.Complement factor D or alternative pathway activation is needed to prevent spontaneous accumulation of C3 and IgM deposits within the mesangium. Complement Factor D/CFD Protein, Rhesus macaq... | |||
TMPK-00790 |
Complement factor H/CFH Protein, Human, Recombinant (His)
ARMD4,AHUS1,H factor 1,HF1,AMBP1,FH,FHL1,HUS,CFHL3,ARMS1,HF2... |
Human | HEK293 Cells |
Factor H is the major soluble inhibitor of complement, where its binding to self markers (i.e., particular glycan structures) prevents complement activation and amplification on host surfaces. Not surprisingly, mutations and polymorphisms that affect recognition of self by factor H are associated with diseases of complement dysregulation, such as age-related macular degeneration and atypical haemolytic uremic syndrome. In addition, pathogens (i.e., non-self) and cancer cells (i.e., altered-self)... | |||
TMPH-00211 |
OmpA Protein, Borrelia burgdorferi, Recombinant (His)
|
Borrelia burgdorferi | P. pastoris (Yeast) |
OmpA Protein, Borrelia burgdorferi, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 29.9 kDa and the accession number is P0A3N6. | |||
TMPH-03272 |
Complement factor D Protein, Rat, Recombinant (His)
Adipsin,Df,Adn,C3 convertase activator,Complement f... |
Rat | P. pastoris (Yeast) |
Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway. | |||
TMPH-00391 |
MOMP Protein, Chlamydia trachomatis serovar L2, Recombinant (His & SUMO)
ompA,Major outer membrane porin |
Chlamydia trachomatis serovar L2 | E. coli |
In elementary bodies (EBs, the infectious stage, which is able to survive outside the host cell) provides the structural integrity of the outer envelope through disulfide cross-links with the small cysteine-rich protein and the large cysteine-rich periplasmic protein. It has been described in publications as the Sarkosyl-insoluble COMC (Chlamydia outer membrane complex), and serves as the functional equivalent of peptidoglycan.; Permits diffusion of specific solutes through the outer membrane. M... | |||
TMPH-02375 |
OmpK36 Protein, Klebsiella pneumoniae, Recombinant
ompK36 |
Klebsiella pneumoniae | E. coli |
OmpK36 Protein, Klebsiella pneumoniae, Recombinant is expressed in E. coli. | |||
TMPY-06767 |
Complement C3 Protein, Mouse, Recombinant (His)
HSE-MSF,complement component 3,Plp,AI25523... |
Mouse | HEK293 Cells |
Complement C3 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.34 kDa and the accession number is NP_033908.2. | |||
TMPY-06538 |
Complement C5 Protein, Cynomolgus, Recombinant
complement component 5 |
Cynomolgus | HEK293 Cells |
Complement C5 Protein, Cynomolgus, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 8.41 kDa and the accession number is XP_005580972.1. | |||
TMPY-02183 |
Complement Factor D/CFD Protein, Human, Recombinant (His)
PFD,DF,complement factor D (adipsin),ADN,FACTOR D,A... |
Human | HEK293 Cells |
Complement Factor D/CFD Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.8 kDa and the accession number is P00746. | |||
TMPK-00755 |
Complement Factor D/CFD Protein, Human, Recombinant (hFc)
C3 convertase activator,DF,AMBP-1,EC 3.4.21,EC 3.4.21.46,Adi... |
Human | HEK293 Cells |
Complement factor D is a serine protease essential for the activation of the alternative pathway and is expressed in the kidney, adipocytes, and macrophages. Factor D is found at relatively high levels in glomeruli suggesting that this component of the complement cascade could influence renal pathophysiology.Complement factor D or alternative pathway activation is needed to prevent spontaneous accumulation of C3 and IgM deposits within the mesangium. Complement Factor D/CFD Protein, Human, Recom... | |||
TMPJ-00417 |
Complement C3a Protein, Human, Recombinant
Anaphylatoxin,C3a,Complement Component C3a |
Human | E. coli |
Complement C3a Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 13 KDa and the accession number is P01024. | |||
TMPK-00776 |
Complement factor I Protein, Human, Recombinant (His)
FIC3b-INA,KAF,IF,CFI,I factor (complement),EC:3.4.2... |
Human | HEK293 Cells |
Complement factor I (CFI) is a serine protease which plays a key role in the modulation of complement system and the induced-fit factor responsible for controlling the complement-mediated processes. Complement factor I Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 64.58 kDa and the accession number is P05156. | |||
TMPK-01268 |
Complement C2 Protein, Cynomolgus, Recombinant (His)
C2,CO2,Complement C2,C3/C5 convertase,ARMD14 |
Cynomolgus | HEK293 Cells |
Single nucleotide polymorphism (SNP) of complement component 2 (C2) has been found to be significantly associated with hepatocellular carcinoma (HCC). Significantly lower C2 expression was found at HCC compared to healthy controls, and C2 was associated with TNM stages. Higher C2 expression was significantly associated with better prognosis, and multivariate analysis showed that C2 was also an independent factor for the prognosis of HCC. | |||
TMPH-00212 |
OmpA Protein, Borrelia burgdorferi, Recombinant (His & Myc)
|
Borrelia burgdorferi | E. coli |
OmpA Protein, Borrelia burgdorferi, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 32.9 kDa and the accession number is P0A3N6. | |||
TMPH-03270 |
Complement C5 Protein, Rat, Recombinant (His & Myc)
Complement C5,C5 |
Rat | E. coli |
Complement C5 Protein, Rat, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 14.0 kDa and the accession number is P08650. | |||
TMPH-02377 |
OmpA Protein, Klebsiella pneumoniae, Recombinant (His & Myc)
Outer membrane protein 3A,Outer membrane protein A,omp |
Klebsiella pneumoniae | E. coli |
With TolR probably plays a role in maintaining the position of the peptidoglycan cell wall in the periplasm. Acts as a porin with low permeability that allows slow penetration of small solutes; an internal gate slows down solute passage.; Required for conjugation with F-type plasmids; probably serves as the mating receptor on recipient cells. | |||
TMPH-00390 |
MOMP Protein, Chlamydia trachomatis, Recombinant (His & Myc)
ompA,Major outer membrane porin, serovar B |
Chlamydia trachomatis | E. coli |
In elementary bodies (EBs, the infectious stage, which is able to survive outside the host cell) provides the structural integrity of the outer envelope through disulfide cross-links with the small cysteine-rich protein and the large cysteine-rich periplasmic protein. It has been described in publications as the Sarkosyl-insoluble COMC (Chlamydia outer membrane complex), and serves as the functional equivalent of peptidoglycan.; Permits diffusion of specific solutes through the outer membrane. M... | |||
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Cat. No. | Product Name | Target | Signaling Pathways |
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TMID-0231 |
α,α,β,β-d4-Serotonin-Creatinine Sulfate Complex H2O
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α,α,β,β-d4-Serotonin-Creatinine Sulfate Complex H2O 是 α,α,β,β-Serotonin-Creatinine Sulfate Complex H2O 的氘代化合物。 |