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TargetMol | Compound Library

抗卵巢癌化合物库现货

Anti-Ovarian Cancer Compound Library

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产品编号 L2196

卵巢癌是一种恶性肿瘤,起源于女性卵巢组织,其中,90%~95%的卵巢癌是原发性癌,即起源于卵巢本身;另外5%~10%的癌症是从其他部位扩散到卵巢的转移癌。卵巢癌的早期阶段通常没有明显症状,即使有症状也不具备特异性,因此早期诊断相对困难。大约60%~70%的患者在就诊时已经进入晚期,而晚期患者的治疗效果较差。虽然卵巢癌的发病率低于宫颈癌和子宫内膜癌,但卵巢癌的死亡率超过了宫颈癌和子宫内膜癌的总和,并且卵巢癌的死亡率呈逐年上升的趋势,严重威胁着女性的健康。如何有效的提高卵巢癌患者的生存期已成为妇科肿瘤亟待攻克的难题。 近年来,分子靶向药物研发取得了突飞猛进的进展。研究发现,针对卵巢癌相关治疗靶点的药物在提升患者生存期方面发挥了显著作用。靶向药物的开发为卵巢癌患者带来了希望,为他们提供了更有效的治疗策略。 TargetMol 抗卵巢癌化合物库收集了2232 种与卵巢癌相关的化合物,包括已经报道具有治疗卵巢癌作用的化合物,以及潜在治疗卵巢癌的化合物,是抗卵巢癌药物研发的良好工具。

TargetMol 的所有产品和服务仅用于科学研究,不能被用于人体,我们也不向个人提供产品和服务。

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产品编号 L2196

抗卵巢癌化合物库

规格

  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
询价 & 定制

产品描述 产品描述

  • 2232种与卵巢癌相关的化合物,可以用于抗卵巢癌药物研发和药理研究;
  • 通路靶点包含PARP、VEGF、PD-1、HER2等;
  • 部分化合物已上市或进入临床期;
  • 详细的说明书,化合物结构、靶点信息、IC50值、活性描述等;
  • NMR、HPLC/LCMS等多种检测技术保证产品结构正确,纯度高,减少假阳性。

Packaging And Storage | TargetMol 包装和储存

  • 可选用DMSO耐受的96/384孔板或2D 条形码编码管;
  • 干粉蓝冰运输,DMSO溶液干冰运输;
  • 排布:96孔板:1st & 12th 空白对照,384孔板:1st & 2nd & 23th & 24th空白对照。

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Library Customization | TargetMol 化合物库组成

Apoptosis
NF-κB
Autophagy
PI3K
EGFR
Reactive Oxygen Species
VEGFR
Wnt/beta-catenin
mTOR
p38 MAPK
Akt
ERK
Estrogen Receptor/ERR
PARP
Endogenous Metabolite
GSK-3
AMPK
Antibacterial
Raf
TGF-beta/Smad
CDK
MAPK
PDGFR
Estrogen/progestogen Receptor
JNK
Ras
Kras
IκB/IKK
MEK
TNF
FGFR
COX
c-Kit
Src
FLT
NOD
DNA-PK
RIP kinase
HER
S6 Kinase
ATM/ATR
Parasite
Antioxidant
ALK
JAK
IL Receptor
STAT
c-Met/HGFR
Caspase
PKC
PDK
IRAK
Antifungal
DNA/RNA Synthesis
Influenza Virus
Ferroptosis
Antibiotic
PPAR
HIV Protease
Calcium Channel
P450
c-RET
Topoisomerase
NO Synthase
PKA
Rho
Bcr-Abl
Aurora Kinase
Nrf2
Casein Kinase
PI4K
Mitophagy
BCL
MMP
IGF-1R
NOD-like Receptor (NLR)
ROS
Mitochondrial Metabolism
Potassium Channel
Dehydrogenase
Tyrosine Kinases
Chk
Lipoxygenase
Microtubule Associated
FAK
p53
BTK
MNK
TLR
c-Fms
HDAC
AChR
NOS
HIF/HIF Prolyl-Hydroxylase
MLK
HCV Protease
ADC Cytotoxin
Virus Protease
ROCK
SIK
PTEN
Epigenetic Reader Domain
Interleukin
Antiviral
HSP
Beta Amyloid
GABA Receptor
Sodium Channel
Tyrosinase
PDE
Drug Metabolite
Syk
TAM Receptor
Tie-2
Phosphatase
Antifection
AChE
P-gp
Trk receptor
MELK
5-HT Receptor
Transferase
TRP/TRPV Channel
E1/E2/E3 Enzyme
HSV
Prostaglandin Receptor
Ephrin Receptor
ASK
HIF
Anti-infection
Proteasome
ATPase
Carbonic Anhydrase
Histone Methyltransferase
Integrin
DYRK
RAAS
TOPK
GTPase
c-Myc
Serine Protease
Serine/threonin kinase
Adrenergic Receptor
MAO
Aryl Hydrocarbon Receptor
LDL
Opioid Receptor
CCR
Porcupine
Free radical scavengers
GPR
SGK
Cannabinoid Receptor
Mdm2
PROTACs
BACE
Reductase
NADPH
Histamine Receptor
Progesterone Receptor
HBV
Pim
RANKL/RANK
CSF-1R
IAP
Gamma-secretase
Glucosidase
DNA Alkylation
cAMP
GluR
CaMK
DUB
Androgen Receptor
PGE Synthase
transporter
Reverse Transcriptase
Aromatase
KLF
PLK
PD-1/PD-L1
S1P Receptor
Chloride channel
ROR
MyD88
DNA Alkylator/Crosslinker
LTR
Adenosine Receptor
IFNAR
RAR/RXR 
Glutathione Peroxidase
MRP
Nucleoside Antimetabolite/Analog
Liver X Receptor
Leukotriene Receptor
PYK2
Glucocorticoid Receptor
Immunology/Inflammation related
IRE1
Myosin
AAK1 (AP2 associated kinase 1)
NMDAR
ACK
Lipid
Beta-Secretase
Acyltransferase
SARS-CoV
STING
LRRK2
AIM2
PAI-1
RSV
GST
Retinoid Receptor
NADPH-oxidase
BMI-1
AhR
Apelin receptor
Proton pump
Adenylyl cyclase
NPC1L1
DHFR
Dopamine Receptor
YAP
Arginase
LPL Receptor
Histone Demethylase
PERK
Necroptosis
gp120/CD4
VDA
OCT
GNRH Receptor
Cysteine Protease
LIM Kinase
Glucokinase
Stemness kinase
iGluR
PAFR
Haspin Kinase
Phosphorylase
Monoamine Transporter
Smo
Fatty Acid Synthase
Hedgehog/Smoothened
CXCR
Somatostatin
Indoleamine 2,3-Dioxygenase (IDO)
SGLT
Wee1
ATP Citrate Lyase
OXPHOS
BCRP
Glutathione reductase
Aminopeptidase
Sirtuin
Histone Acetyltransferase
Decarboxylase
cGAS
Methionine Adenosyltransferase (MAT)
Hippo pathway
GPX
Ligand for E3 Ligase
CRISPR/Cas9
Phospholipase
Hydroxylase
RXFP receptor
Adenosine deaminase
DAPK
Discoidin Domain Receptor (DDR)
Platelet aggregation
cholecystokinin
Protease-activated Receptor
ROS Kinase
CFTR
PKM
Monoamine Oxidase
Kinesin

Keywords