购物车
- 全部删除
- 您的购物车当前为空
PIC1 PA是一种含有15个氨基酸的肽,是一种有效的PIC1类似物,能够抑制经典途径介导的补体激活。它在功能上干扰C1s-C1r-C1r-C1s/MASPs与C1q/MBL胶原样区(CLR)的交互作用。PIC1 PA可以特异性结合C1q的CLR,与纯化的C1q结合时的平均平衡解离常数(KD)为33.3 nM。
PIC1 PA是一种含有15个氨基酸的肽,是一种有效的PIC1类似物,能够抑制经典途径介导的补体激活。它在功能上干扰C1s-C1r-C1r-C1s/MASPs与C1q/MBL胶原样区(CLR)的交互作用。PIC1 PA可以特异性结合C1q的CLR,与纯化的C1q结合时的平均平衡解离常数(KD)为33.3 nM。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
10 mg | 询价 | 期货 | |
50 mg | 询价 | 期货 |
产品描述 | PIC1 PA, a peptide consisting of 15 amino acids, serves as an effective analog of PIC1 that inhibits complement activation mediated by the classical pathway. Functionally, PIC1 PA interferes with the interaction between the C1s-C1r-C1r-C1s/MASPs and the collagen-like region (CLR) of C1q/MBL. It specifically binds to the CLR of C1q, with an average equilibrium dissociation constant (KD) of 33.3 nM when binding purified C1q. |
分子量 | 1642.98 |
分子式 | C71H123N19O21S2 |
CAS No. | 1356469-36-7 |
存储 | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
评论内容