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Targets Recommended: Epigenetic Reader Domain

268

抑制剂 & 化合物

88

天然产物

5

化合物库

252

重组蛋白

4

同位素标记化合物

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Cat. No. Product Name
L7900 成骨分子库

317 compounds
317 种成骨相关的生物活性小分子化合物的特有集合,用于高通量、高内涵筛选;
L8400 血液病分子库

514 compounds
514 种造血系统疾病相关的生物活性小分子化合物的特有集合,用于高通量、高内涵筛选;
L9810 抗纤维化化合物库

1180 compounds
1180 种潜在的抗纤维化分子,是研究纤维化的有效工具,可以用于高通量筛选和高内涵筛选;
L6230 苗药化合物库

534 compounds
534种苗族特色药材的天然产物分子,可用于高通量和高内涵筛选
L8000 干细胞分化化合物库

1197 compounds
1197 种干细胞分化信号通路相关的生物活性小分子化合物的特有集合,可用于高通量、高内涵筛选;

化合物库

成骨分子库
Cat.No: L7900
Compounds: 317
血液病分子库
Cat.No: L8400
Compounds: 514
抗纤维化化合物库
Cat.No: L9810
Compounds: 1180
苗药化合物库
Cat.No: L6230
Compounds: 534
干细胞分化化合物库
Cat.No: L8000
Compounds: 1197
Cat. No. Product Name Target Signaling Pathways
T1973 PFI-4

PFI4

Epigenetic Reader Domain Chromatin/Epigenetic
PFI-4是一种可渗透细胞的选择性BRPF1溴结构域抑制剂,IC50为 80 nM,作用于BRPF1比作用于其他溴结构域选择性强 100 多倍。
T1850 Balicatib

AAE581,巴利卡替

Cysteine Protease Proteases/Proteasome
Balicatib (AAE581) 是组织蛋白酶K 抑制剂,其对组织蛋白酶K 的抑制作用是组织蛋白酶B、L 和S 的抑制性的10到100倍。
T8550 NDMC101

Others; NF-κB; Proteasome NF-κB; Others; Proteases/Proteasome; Ubiquitination
NDMC101 是有效的破骨细胞形成抑制剂,通过下调 NFATc1 调控基因表达抑制破骨细胞分化。它与 DPP4底物相似,通过抑制DPP4抑制早期 T 细胞激活。它能够用于骨疾病的研究,如类风湿关节炎、滑膜炎等。
T7469 Alendronic Acid

alendronate,阿仑膦酸

Others Others
Alendronic Acid (alendronate) 是法呢基二磷酸合酶(FDPS)抑制剂,是一种双膦酸盐。它能够抑制破骨细胞介导的骨吸收,对绝经后骨质疏松症,恶性高钙血症和 Paget 病具有疗效。
T22702 CYM 50769

Neuropeptide W GPCR/G Protein; Neuroscience
CYM 50769是神经肽 B/W 受体 1 的一种选择性拮抗剂。CYM 50769可抑制 NPW-23 诱导的 ATDC5 细胞增殖。CYM 50769在软骨内骨形成方面有研究价值。
T39508 KY-02327

Others Others
KY-02327 是 KY-02061的一种类似物,具有代谢稳定性。KY-02327是Dishevelled (Dvl)-CXXC5相互作用抑制剂。KY-02327激活Wnt/β-catenin 途径,从而促进成骨细胞分化。
T2121 SW033291

Dehydrogenase Metabolism
SW033291 是有效的15-PGDH 抑制剂,与15-PGDH 亲和力高,Ki 为 0.1 nM。它增加骨髓和其他组织中前列腺素 PGE2 的水平。它还可促进组织再生。
T21616 L-006235

L 006235

Cysteine Protease Proteases/Proteasome
L-006235 是一种口服有活性的、可逆的cathepsin K 选择性抑制剂,在骨吸收试验中的IC50值为 5 nM。它能够抑制胶原蛋白降解,并较少骨质流失。
T38776 LP-922056

Wnt/beta-catenin Cytoskeletal Signaling; Stem Cells
LP-922056 是 Notum Pectinacetylesterase 的抑制剂,对人和小鼠的 EC50 值分别为 21 nM 和 55 nM。
T1867 Otenaproxesul

ATB 346

Apoptosis; COX Apoptosis; Immunology/Inflammation; Neuroscience
Otenaproxesul (ATB 346) 是一种具有口服活性的非甾体抗炎药,可抑制环氧合酶-1 和 2,具有抗炎生物活性,可用于缓解疼痛的研究。
T8645 PF-06446846

Others Others
PF-06446846 是口服有活性的 PCSK9抑制剂。它能够在密码子区域附近阻断 80S ribosome,选择性地直接抑制 PCSK9 的翻译。
T6574 Lumiracoxib

Prexige,罗美昔布,COX-189

COX Immunology/Inflammation; Neuroscience
Lumiracoxib (Prexige) 是强选择性有口服活性的 COX-2抑制剂,Ki 值为 0.06 μM。它是非选择性非甾体抗炎试剂,具有抗炎和解热活性,可用于骨关节炎和骨癌研究。
T2334 Avanafil

阿伐那非,TA1790

PDE Metabolism
Avanafil (TA1790) 是一种高活性PDE-5抑制剂,IC50=5.2 nM,对PDE1,PDE6和PDE11活性较低。
T13324 VUF11207 fumarate

CXCR; Arrestin Autophagy; GPCR/G Protein; Immunology/Inflammation
VUF11207 fumarate 是一种 CXCR7激动剂和高效CXCR7配体,pKi 为 8.1。它可诱导CXCR7的β-arrestin2募集和随后的内在化,pEC50分别为 8.8 和 7.9。
T1817 GNF-2

GNF2

SARS-CoV; Bcr-Abl Angiogenesis; Cytoskeletal Signaling; Microbiology/Virology; Tyrosine Kinase/Adaptors
GNF-2 是一种高选择性的非 ATP 竞争性 Bcr-Abl 抑制剂。 它抑制 Ba/F3.p210 增殖,IC50为 138 nM。
T23383 SR11237

SR 11237

Others; RAR/RXR  Metabolism; Others
SR11237 是一种泛视黄醇 X 受体 (RXR) 激动剂。 SR11237 导致 RXR/RXR 同源二聚体形成并反式激活包含 RXR 反应元件的报告基因。
T6451 Clodronic acid disodium salt

Loron,Clodronate Disodium,氯屈膦酸二钠,Lodronate

Others Others
Clodronic acid disodium salt (Lodronate) 是一种口服具有活力的破骨细胞骨吸收 (osteoclastic bone resorption) 的抑制剂,是一代双磷酸盐。它可用于高骨转换状态、Paget’s 病和溶骨性骨转移中。
T1944 LDN-214117

ALK; TGF-beta/Smad Angiogenesis; Stem Cells; Tyrosine Kinase/Adaptors
LDN214117 是一种高效的 ALK2 选择性抑制剂(IC50:22nM),也是一种 BMP6 抑制剂(IC50:100nM),对ALK5抑制力弱100倍。
T23146 PHA 568487 free base

PHA 568487

AChR Neuroscience
PHA 568487 free base 是一种选择性的 α7 烟碱乙酰胆碱受体激动剂,可用于减缓神经炎症。
T21460 Teriparatide acetate

hPTH 1-34 (acetate salt),Parathar acetate,Forteo,醋酸立特帕肽

Others Others
Teriparatide acetate (Forteo) 是一种 PHT 激动剂,在 HEK293 细胞中的 IC50 为 2 nM。Teriparatide acetate 是一种重组形式的甲状旁腺激素。它是一种有效的合成代谢(即骨骼生长)剂,用于治疗某些形式的骨质疏松症。间歇使用特立帕肽比破骨细胞更能激活成骨细胞,从而导致骨骼整体增加。
T6374 Alfacalcidol

Bondiol,Etalpha,阿法骨化醇,1-hydroxy Vitamin D3,1.alpha.-Hydroxyvitamin D3,1-hydroxycholecalciferol

Others Others
Alfacalcidol (Etalpha) 是一种维生素 D3 衍生物,是非选择性的维生素 D 受体活化剂,有用于骨质疏松研究的潜力。
T15259 Evatanepag

CP-533536 free acid,2-[3-[N-(4-叔丁基苄基)-N-(吡啶-3-基磺酰基)氨基甲基]苯氧基]乙酸

Prostaglandin Receptor GPCR/G Protein; Immunology/Inflammation
Evatanepag (CP-533536 free acid) 是一种 EP2 受体选择性前列腺素 E2 (PGE2) 激动剂,可诱导局部骨形成,EC50 为 0.3 nM。它在大鼠骨折愈合模型中以单剂量局部给药时表现出愈合骨折的能力。
T6906 Tamoxifen

ICI 46474,他莫昔芬,Z-Tamoxifen,trans-Tamoxifen,ICI47699

Apoptosis; Estrogen Receptor/ERR; HSP; Estrogen/progestogen Receptor; Autophagy Apoptosis; Autophagy; Cytoskeletal Signaling; Endocrinology/Hormones; Metabolism
Tamoxifen (ICI47699) 是一种雌激素受体调节剂 (SERM),具有选择性和口服有效性。Tamoxifen 对雌激素具有抑制活性 (如乳腺细胞) 和激活活性 (如骨、肝和子宫细胞)。
T7566 GRGDSPK

EMD 56574

Others Others
GRGDSPK (EMD 56574) 是一种包含精氨酸-甘氨酸-天冬氨酸 (RGD) 的多肽,也是一种竞争性且可逆的抑制肽,可抑制整联蛋白-纤连蛋白结合,可用于整联蛋白在骨形成和吸收中作用的研究。
T0835 Tamoxifen Citrate

Tamoxifen Z-isomer citrate,ICI 46474,ICI 46474 Citrate,枸橼酸他莫昔芬,他莫昔芬柠檬酸盐

Apoptosis; Estrogen Receptor/ERR; HSP; Estrogen/progestogen Receptor; Autophagy Apoptosis; Autophagy; Cytoskeletal Signaling; Endocrinology/Hormones; Metabolism
Tamoxifen Citrate 是一种口服有效的,选择性雌激素受体调节剂,可阻断乳腺细胞中的雌激素作用,并可激活如骨骼、肝脏和子宫细胞中的雌激素活性。它是 Hsp90激活剂,可增强 Hsp90 分子伴侣 ATPase 的活性,可激活自噬和诱导凋亡。
T20419 Raloxifene

Pharoxifene,雷洛昔芬,Raloxifenum,Keoxifene,LY-139481

Estrogen Receptor/ERR; Others Endocrinology/Hormones; Others
Raloxifene (LY-139481) 是一种苯并噻吩类化合物,是一种选择性雌激素受体 (estrogen receptor) 调节剂 (SERM),对骨、血脂有雌激素激动作用,对乳腺和子宫有雌激素拮抗作用。它用于乳腺癌和骨质疏松症研究。
T16159 Muramyl dipeptide

MDP

NOD Immunology/Inflammation; NF-κB
Muramyl dipeptide (MDP) 是合成的免疫反应肽,由 N-乙酰壁酸与 L-Ala-D-isoGln 的短氨基酸链相连。它通过MAPK 途径上调 Runx2 基因表达,直接促进成骨细胞分化,通过降低 RANKL/OPG 比值间接抑制破骨细胞分化。它是通过Runx2诱导骨形成的诱导因子,也是NLRP1激动剂。
T1925 PLX647

c-Fms; c-Kit Tyrosine Kinase/Adaptors
PLX647 是具有口服活性的、高效的、特异性的FMS 和KIT 双激酶抑制剂,IC50分别为 28 和 16 nM。它 (1 μM) 在 400 个激酶组中显示出对 FMS 和 KIT 有选择性,但 FLT3 和 KDR 除外 (IC50=91 和 130 nM)。
T9026 MEISi-2

Benzoic acid, 4-hydroxy-, 2-[(Z)-(2-oxo-1(2H)-naphthalenylidene)methyl]hydrazide

Others Others
MEISi-2 是 MEIS(造血干细胞自我更新的关键调控因子)选择性抑制剂。它可用于心脏损伤、造血问题、骨髓移植和癌症的研究。
T29978 Amicibone

Amicibono

Others Others
Amicibone is a biochemical.
T8400 Pamidronic acid

Wnt/beta-catenin Cytoskeletal Signaling; Stem Cells
Pamidronic acid 可用于各种骨吸收类疾病的研究。
T0308 Etidronic acid

HEDPA,Etidronate,HEDP,羟乙磷酸

Apoptosis; Phosphatase; Others; HBV Apoptosis; Metabolism; Microbiology/Virology; Others
Etidronic acid (HEDP) 是一种影响钙代谢的二膦酸盐,抑制异位钙化并减缓骨吸收和骨转换,可应用于洗涤,水处理,化妆品和制药业。
T13911 Tacalcitol monohydrate

Curatoderm monohydrate,TV 02 monohydrate,TV-02H monohydrate,1,24(R)-Dihydroxyvitamin D3 monohydrate

Cysteine Protease Proteases/Proteasome
Tacalcitol monohydrate(Curatoderm monohydrate) 是一种维生素 D3 类似物,能通过调节钙离子促进骨发育,可用于研究银屑病。
T19415 Medronic acid

亚甲基二磷酸,Methylenediphosphonic acid

Others Others
Medronic acid (Methylenediphosphonic acid) 是一种亚甲基取代的二膦酸盐。它对骨基质中的羟基磷灰石晶体的表面具有亲和力,并且可粘附在其表面。它能够在类骨质矿化的位点累积,可以在骨成像中与放射性同位素复合使用。
T9603 MNITMT

Others Others
MNITMT 是一种有效的免疫抑制剂 (immunosuppressive agent),没有骨髓毒性。
T25492 Hepln-13

Hepln 13,Hepln13

c-Met/HGFR Tyrosine Kinase/Adaptors
Hepln-13 是具有口服活性的Hepsin 抑制剂(IC50:0.33 µM)。它可用于研究转移性前列腺癌。
T0379 Risedronic Acid

Risedronate,利塞膦酸

Others; Transferase Metabolism; Others
Risedronic Acid (Risedronate) 具有抑制破骨细胞介导的骨重吸收的作用。
T19501 Pamidronate disodium pentahydrate

Others Others
Pamidronate disodium pentahydrate 是一种骨吸收抑制剂,能够预防骨质疏松症的化合物。
T1641 Strontium ranelate

Distrontium renelate,S12911,雷尼酸锶

Calcium Channel; CaSR GPCR/G Protein; Membrane transporter/Ion channel; Metabolism
Strontium ranelate (S12911) 是抗骨质疏松的药物,能够抑制骨吸收,促进骨形成,进而促使正骨平衡。它还能够激活非骨骼细胞中的钙敏感受体 (CaSR),进而促进肌醇 1,4,5-三磷酸的生成及丝裂原活化的蛋白激酶信号转导。
T0575 1-Methylimidazole

Others Others
1-Methylimidazole 是1-methyl-2-thioimidazole (methimazole)的代谢物,可抑制骨吸收。
T20112 Triphenyl bismuth

NSC 465,三苯基铋,NSC-465,NSC465

Others Others
Triphenyl bismuth (NSC-465) 是一种添加剂,用于使生物医学树脂在 X 射线图像上可见,并可用作骨科骨水泥的不透射线剂。
T77581 KM02894

GluR Neuroscience
KM02894 是一种谷氨酸释放抑制剂。癌细胞释放高水平的谷氨酸,能够破坏正常的骨转换,这可能导致癌症引起的骨痛。KM02894 可用于研究肿瘤相关疾病。
T0309 Ipriflavone

Osteofix,依普黄酮

advanced glycation end products Others
Ipriflavone (Osteofix) 是一种合成异黄酮衍生物,可用于抑制骨吸收。
T8489 Minodronic acid monohydrate

Transferase Metabolism
Minodronic acid monohydrate 是一种法尼基二磷酸合成酶抑制剂,可作为骨吸收抑制剂。
T11956L MBC-11

Others Others
MBC-11 通过将阿糖胞苷和依替膦酸盐浓缩在疾病部位来靶向癌症的偶联物。MBC-11 可溶用于研究肿瘤诱发的骨病。
T2188 Thonzonium Bromide

嘧苯十六铵,通佐溴胺

Proton pump; Antibacterial; Autophagy Autophagy; Membrane transporter/Ion channel; Microbiology/Virology
Thonzonium bromide 是一种单阳离子表面活性剂,在结构上与 Farnesol 相似的抗菌剂。它以剂量依赖的方式抑制质子转运 (EC50=69 μM)。在体外可抑制 RANKL 诱导的破骨细胞形成和骨吸收,并在体内阻止 LPS 诱导的骨丢失。
T29071 UR13870

Org 48762-0,POLB 001,UR-13870,UR 13870

p38 MAPK MAPK
UR-13870 (Org 48762-0) 是一种具有口服活性和选择性的 p38 丝裂原活化蛋白激酶(MAPK)抑制剂,可防止小鼠胶原诱导的关节炎中的骨损伤。
T4662 SJ000291942

TGF-beta/Smad Stem Cells
SJ000291942 是一种经典骨形态发生蛋白 (BMP) 信号传导途径的激活剂。其中 BMP 是一种转化生长因子 β 分泌信号分子家族的成员。
T6373 Alendronate sodium hydrate

G-704650,Alendronate,MK 217,Alendronate sodium trihydrate,阿仑膦酸钠,G-704650 Adronat,Fosamax

Transferase Metabolism
Alendronate sodium hydrate (MK 217) 是 farnesyl diphosphate synthase 抑制剂(IC50:460 nM)。
T7566L1 GRGDSPK acetate

GRGDSPK acetate(111119-28-9 Free base)

Beta Amyloid Neuroscience
GRGDSPK acetate 显示出对整合素-纤连蛋白结合的抑制活性,可用于研究整合素在骨形成和吸收中的作用。

化合物

PFI-4
Cat.No: T1973
Synonym: PFI4
Target: Epigenetic Reader Domain
Balicatib
Cat.No: T1850
Synonym: AAE581,巴利卡替
Target: Cysteine Protease
NDMC101
Cat.No: T8550
Synonym:
Target: Others, NF-κB, Proteasome
Alendronic Acid
Cat.No: T7469
Synonym: alendronate,阿仑膦酸
Target: Others
CYM 50769
Cat.No: T22702
Synonym:
Target: Neuropeptide W
KY-02327
Cat.No: T39508
Synonym:
Target: Others
SW033291
Cat.No: T2121
Synonym:
Target: Dehydrogenase
L-006235
Cat.No: T21616
Synonym: L 006235
Target: Cysteine Protease
LP-922056
Cat.No: T38776
Synonym:
Target: Wnt/beta-catenin
Otenaproxesul
Cat.No: T1867
Synonym: ATB 346
Target: Apoptosis, COX
PF-06446846
Cat.No: T8645
Synonym:
Target: Others
Lumiracoxib
Cat.No: T6574
Synonym: Prexige,罗美昔布,COX-189
Target: COX
Avanafil
Cat.No: T2334
Synonym: 阿伐那非,TA1790
Target: PDE
VUF11207 fumarate
Cat.No: T13324
Synonym:
Target: CXCR, Arrestin
GNF-2
Cat.No: T1817
Synonym: GNF2
Target: SARS-CoV, Bcr-Abl
SR11237
Cat.No: T23383
Synonym: SR 11237
Target: Others, RAR/RXR 
Clodronic acid disodium salt
Cat.No: T6451
Synonym: Loron,Clodronate Disodium,氯屈膦酸二钠,Lodronate
Target: Others
LDN-214117
Cat.No: T1944
Synonym:
Target: ALK, TGF-beta/Smad
PHA 568487 free base
Cat.No: T23146
Synonym: PHA 568487
Target: AChR
Teriparatide acetate
Cat.No: T21460
Synonym: hPTH 1-34 (acetate salt),Parathar acetate,Forteo,醋酸立特帕肽
Target: Others
Alfacalcidol
Cat.No: T6374
Synonym: Bondiol,Etalpha,阿法骨化醇,1-hydroxy Vitamin D3,1.alpha.-Hydroxyvitamin D3,1-hydroxycholecalciferol
Target: Others
Evatanepag
Cat.No: T15259
Synonym: CP-533536 free acid,2-[3-[N-(4-叔丁基苄基)-N-(吡啶-3-基磺酰基)氨基甲基]苯氧基]乙酸
Target: Prostaglandin Receptor
Tamoxifen
Cat.No: T6906
Synonym: ICI 46474,他莫昔芬,Z-Tamoxifen,trans-Tamoxifen,ICI47699
Target: Apoptosis, Estrogen Receptor/ERR, HSP, Estrogen/progestogen Receptor, Autophagy
GRGDSPK
Cat.No: T7566
Synonym: EMD 56574
Target: Others
Tamoxifen Citrate
Cat.No: T0835
Synonym: Tamoxifen Z-isomer citrate,ICI 46474,ICI 46474 Citrate,枸橼酸他莫昔芬,他莫昔芬柠檬酸盐
Target: Apoptosis, Estrogen Receptor/ERR, HSP, Estrogen/progestogen Receptor, Autophagy
Raloxifene
Cat.No: T20419
Synonym: Pharoxifene,雷洛昔芬,Raloxifenum,Keoxifene,LY-139481
Target: Estrogen Receptor/ERR, Others
Muramyl dipeptide
Cat.No: T16159
Synonym: MDP
Target: NOD
PLX647
Cat.No: T1925
Synonym:
Target: c-Fms, c-Kit
MEISi-2
Cat.No: T9026
Synonym: Benzoic acid, 4-hydroxy-, 2-[(Z)-(2-oxo-1(2H)-naphthalenylidene)methyl]hydrazide
Target: Others
Amicibone
Cat.No: T29978
Synonym: Amicibono
Target: Others
Pamidronic acid
Cat.No: T8400
Synonym:
Target: Wnt/beta-catenin
Etidronic acid
Cat.No: T0308
Synonym: HEDPA,Etidronate,HEDP,羟乙磷酸
Target: Apoptosis, Phosphatase, Others, HBV
Tacalcitol monohydrate
Cat.No: T13911
Synonym: Curatoderm monohydrate,TV 02 monohydrate,TV-02H monohydrate,1,24(R)-Dihydroxyvitamin D3 monohydrate
Target: Cysteine Protease
Medronic acid
Cat.No: T19415
Synonym: 亚甲基二磷酸,Methylenediphosphonic acid
Target: Others
MNITMT
Cat.No: T9603
Synonym:
Target: Others
Hepln-13
Cat.No: T25492
Synonym: Hepln 13,Hepln13
Target: c-Met/HGFR
Risedronic Acid
Cat.No: T0379
Synonym: Risedronate,利塞膦酸
Target: Others, Transferase
Pamidronate disodium pentahydrate
Cat.No: T19501
Synonym:
Target: Others
Strontium ranelate
Cat.No: T1641
Synonym: Distrontium renelate,S12911,雷尼酸锶
Target: Calcium Channel, CaSR
1-Methylimidazole
Cat.No: T0575
Synonym:
Target: Others
Triphenyl bismuth
Cat.No: T20112
Synonym: NSC 465,三苯基铋,NSC-465,NSC465
Target: Others
KM02894
Cat.No: T77581
Synonym:
Target: GluR
Ipriflavone
Cat.No: T0309
Synonym: Osteofix,依普黄酮
Target: advanced glycation end products
Minodronic acid monohydrate
Cat.No: T8489
Synonym:
Target: Transferase
MBC-11
Cat.No: T11956L
Synonym:
Target: Others
Thonzonium Bromide
Cat.No: T2188
Synonym: 嘧苯十六铵,通佐溴胺
Target: Proton pump, Antibacterial, Autophagy
UR13870
Cat.No: T29071
Synonym: Org 48762-0,POLB 001,UR-13870,UR 13870
Target: p38 MAPK
SJ000291942
Cat.No: T4662
Synonym:
Target: TGF-beta/Smad
Alendronate sodium hydrate
Cat.No: T6373
Synonym: G-704650,Alendronate,MK 217,Alendronate sodium trihydrate,阿仑膦酸钠,G-704650 Adronat,Fosamax
Target: Transferase
GRGDSPK acetate
Cat.No: T7566L1
Synonym: GRGDSPK acetate(111119-28-9 Free base)
Target: Beta Amyloid
Cat. No. Product Name Target Signaling Pathways
T5751 Tigogenin

Others Others
Tigogenin 是甾体皂甙元,普遍用于甾体类药物的合成。它能够阻碍小鼠骨髓基质细胞脂肪细胞分化,促使成骨细胞的分化。
T5S2129 Sciadopitysin

TNF; NF-κB Apoptosis; NF-κB
Sciadopitysin 是一种双黄酮类化合物,来自银杏叶片中。它通过抑制NF-κB 活化并降低c-Fos 和NFATc1的表达来抑制 RANKL 诱导的破骨细胞生成和骨丢失。
T5575 Cycloastragenol

环黄芪醇,Cyclogalegenol,Astramembrangenin

Epigenetic Reader Domain; Telomerase Chromatin/Epigenetic; DNA Damage/DNA Repair
Cycloastragenol (Astramembrangenin) 是一种三萜皂苷类化合物,是黄芪主要活性成分的水解产物,具有抗氧化、抗炎、抗衰老、抗凋亡和心血管保护作用。它是端粒酶激活剂,可以延长端粒,还能缓解与年龄相关的骨丢失,改善骨微结构和生物力学特性。
TN1494 Cimicifugoside H-1

黑升麻苷H-1

Others Others
Cimicifugoside H1 是C. foetidaL.C 提取物的主要成分,是一种环甾烷醇木糖苷。它对骨吸收及卵巢切除术引起的骨质流失具有抑制作用。
T4S0969 Obtusifolin

决明蒽醌,决明蒽醌;美决明子素

Antioxidant; NF-κB NF-κB; oxidation-reduction
Obtusifolin 是分离自决明子的种子中,能够抑制NF-kB 通路,调节气道上皮细胞中 MUC5AC 粘蛋白的基因表达和产生。它通过靶向甲状旁腺激素相关蛋白来抑制邻苯二甲酸酯诱导的乳腺癌骨转移。
T2902 Costunolide

Costus lactone,NSC 106404,Costunolid,(+)-Costunolide,木香烃内酯

Apoptosis; Endogenous Metabolite; Telomerase Apoptosis; DNA Damage/DNA Repair; Metabolism
Costunolide (Costus lactone) 是一种天然的倍半萜内酯,具有抗氧化、抗炎、抗过敏、骨重塑、神经保护、促进毛发生长、抗癌和抗糖尿病的特性,可诱导乳腺癌细胞周期阻滞和凋亡。
T2988 (-)-Epigallocatechin Gallate

Epigallocatechol Gallate,(-)-表没食子儿茶素没食子酸酯,EGCG

Ferroptosis; Reactive Oxygen Species; HIV Protease; Mitochondrial Metabolism; Endogenous Metabolite; Autophagy Apoptosis; Autophagy; Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB; Proteases/Proteasome
(-)-Epigallocatechin Gallate (EGCG) 属于茶类黄酮天然产物,可抑制 EGFR 信号传导,抑制 GLUD 1/2。(-)-Epigallocatechin Gallate 具有抗氧化、抗炎和抗肿瘤活性。(-)-Epigallocatechin Gallate 可以通过激活细胞色素 c 氧化酶来诱导氧化磷酸化。
TN7036 N-(3-Methoxybenzyl)-(9Z,12Z,15Z)-octadecatrienamide

(9Z,12Z,15Z)-N-[(3-Methoxyphenyl)methyl]-9,12,15-octadecatrienamide,间-甲氧基苄基-亚麻酰胺,Macamide Impurity 14

Wnt/beta-catenin Cytoskeletal Signaling; Stem Cells
N-(3-Methoxybenzyl)-(9Z,12Z,15Z)-octadecatrienamide (Macamide Impurity 14) 是一种从玛卡中分离得到的玛卡酰胺。它能够激活典型的Wnt/β‐catenin 信号通路,诱导间充质干细胞成骨分化和随后的骨形成,可用于研究骨质疏松症。
T5712 zerumbone

花薑酮,球姜酮

Antioxidant; HSV Microbiology/Virology; oxidation-reduction
Zerumbone 是从Zingiber zerumbetSmith 的根茎中分离的一种单环倍半萜烯,可有效抑制Epstein-Barr 病毒的激活,IC50为 0.14 mM,具有抗癌、抗炎、抗氧化和抗增殖的作用。
T24744 Rubone

Others Others
Rubone is the tumor suppressor miRNA-34a modulator that acts by inhibiting the growth of hepatocellular carcinoma.
T13768 (+)-Medicarpin

Estrogen/progestogen Receptor Endocrinology/Hormones
(+)-Medicarpin, a pterocarpan, is an isoflavonoid compound derived from multiple medicinal plant species such as Sophora japonica, Zollernia paraensis, Platymiscium yucatamun, Machaerium aristulatum, and Platymiscium floribundum. It exhibits potent inhibition of osteoclastogenesis and facilitates bone healing and increased bone mass through osteoblast differentiation, which is mediated by the estrogen receptor (ER) β.
T3488 Tectorigenin

4',5,7-Trihydroxy-6-methoxyisoflavone,Tectorigenine,鸢尾黄酮,鸢尾黄素

Apoptosis Apoptosis
Tectorigenin (4',5,7-Trihydroxy-6-methoxyisoflavone) 是一种从葛根汤干燥的花中分离出来的植物异黄酮。
T0912 Tetracycline hydrochloride

NCI-c55561,盐酸四环素,Tetracycline HCl

ribosome; Antibacterial; Antibiotic Microbiology/Virology
Tetracycline hydrochloride (NCI-c55561) 是一种广谱抗生素,抑制多种革兰氏阳性和革兰氏阴性细菌。
TN1117 Veraguensin

p38 MAPK; NF-κB; Antibiotic; Parasite; Antifection MAPK; Microbiology/Virology; NF-κB
Veraguensin 来源于 Magnolia sp.。 Veraguensin 抑制骨吸收并显示出高抗寄生虫活性。
TJS0856 Dalbergin

黄檀素,6-Hydroxy-7-Methoxy-4-Phenylcoumarin

Others Others
Dalbergin (6-Hydroxy-7-Methoxy-4-Phenylcoumarin) 是一种 Dalbergia Sissoo Linn. knot wood 提取物的成分。它具有强大的抗氧化活性。
T2820 Glycitin

黄豆黄苷,Glycitein-7-β-O-glucoside,Glycitein 7-O-β-glucoside

Others; Influenza Virus; Antibacterial Microbiology/Virology; Others
Glycitin (Glycitein 7-O-β-glucoside) 是一种从豆类中分离出来的天然异黄酮,有抗菌,抗病毒和雌激素作用,还有促进骨髓基质细胞和成骨细胞的增殖和抑制骨转换的生物学功能。
TN2143 3,7,4'-Trihydroxyflavone

Resokaempferol,5-Deoxykampferol

DNA DNA Damage/DNA Repair
3,7,4'-Trihydroxyflavone(5-Deoxykampferol) 是从黄檀心材中分离得到的一种具有 DNA 断链活性的黄酮类化合物,可抑制 NF-κB 配体 (RANKL) 受体激活剂诱导的 RAW 264.7 细胞和骨髓巨噬细胞中的破骨细胞分化、肌动蛋白环形成和骨吸收。
T8103 H-HoArg-OH

Endogenous Metabolite; Phosphorylase Metabolism
H-HoArg-OH 是人骨和肝脏碱性磷酸酶(alkaline phosphatase)的强效抑制剂,是一种精氨酸的同系物。
T3S2312 Poncirin

枸橘苷,Isosakuranetin-7-neohesperidoside

Apoptosis; Others Apoptosis; Others
Poncirin (Isosakuranetin-7-neohesperidoside) 是从三叶草中分离出来的一种天然产物,具有抗炎活性。 它防止脂肪生成,增强间充质干细胞中的成骨细胞分化,增加骨矿物质密度,改善小梁微结构,可能反映 GIO 小鼠的骨形成增加和骨吸收减少。
T3004 Batilol

鲨肝醇,Batilolum,Stearyl monoglyceride,Batyl alcohol,1-O-Octadecylglycerol

Others; Endogenous Metabolite Metabolism; Others
Batilol (Stearyl monoglyceride) 是内源性代谢产物的一种。
T7437 3-(3-Hydroxyphenyl)propionic Acid

m-Hydroxyphenylpropionic acid,3-Hydroxyhydrocinnamic acid,3-(3-羟基苯基)丙酸

Others; Endogenous Metabolite Metabolism; Others
3-(3-Hydroxyphenyl)propionic Acid (m-Hydroxyphenylpropionic acid) 是一种黄酮类代谢产物,由人体微生物区系形成,具有舒张血管的特性。
T2845 Imperatorin

Ammidin,8-Isoamylenoxypsoralen,欧前胡素,8-Isopentenyloxypsoralene,Marmelosin,Pentosalen

TRP/TRPV Channel; AChR; AChE; NOD Immunology/Inflammation; Membrane transporter/Ion channel; Neuroscience; NF-κB
Imperatorin (8-Isopentenyloxypsoralene) 是NO synthesis 和BChE 的抑制剂,IC50分别为 9.2 μmol 和 31.4 μmol。它也是TRPV1的微弱激动剂,EC50为 12.6±3.2 μM。
T3808 Icariside I

淫羊藿次苷I,Lcariside I,Icariin I,Icarisid I

Others Others
Icariside I (Lcariside I) 是一种 Icarlin 的代谢产物,具有调节骨重塑的作用,可用于研究骨质疏松。
TN3209 3′,4′,7-Trihydroxyflavone 

ATPase; Others; p38 MAPK; NF-κB MAPK; Membrane transporter/Ion channel; NF-κB; Others
3',4',7-Trihydroxyflavone 是分离自蚕豆荚的黄酮苷元化合物。
T5S0662 Gelsemine

钩吻碱,Gelsemin

Antioxidant oxidation-reduction
Gelsemine (Gelsemin) 是一种从中草药 Gelsemium elegans 中获得的生物碱,具有抗伤害和促进睡眠活性,可有效缓解慢性疼痛。
T2980 Chondroitin sulfate

Chonsurid,Chondroitin polysulfate,硫酸软骨素

MMP; Others; Endogenous Metabolite; NO Synthase Immunology/Inflammation; Metabolism; Others; Proteases/Proteasome
Chondroitin sulfate (Chonsurid) 是一种糖胺聚糖,被广泛用于骨关节炎的研究。它能够减少炎症介质和凋亡过程,并能够减少炎性细胞因子,iNOS 和MMPs 产生。
T6S1657 Paeonolide

Others Others
Paeonolide 是一种广泛存在于 Paeonia 属植物根中的植物糖苷,是骨形成细胞中核心结合因子亚基 α-1 的新型调节剂。
T6S1966 Curculigoside

Curculigoside A,仙茅苷

Antioxidant; NF-κB; JAK; STAT Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; NF-κB; oxidation-reduction; Stem Cells
Curculigoside (Curculigoside A) 是仙茅中的主要皂苷,具有显著的抗氧化、抗骨质疏松、抗抑郁和神经保护作用。它通过调节JAK/STAT/NF-κB 信号传导途径,具有抗关节炎作用。
T3662 Eleutheroside E

NF-κB NF-κB
Eleutheroside E 是刺五加的重要成分,具有抗炎,保护缺血心脏的功能。
T3924 Astragaloside II

黄芪皂苷 II,Astrasieversianin VIII

TGF-beta/Smad Stem Cells
Astragaloside II (Astrasieversianin VIII) 是一种分离自黄芪中的天然化合物。
T3S0137 Bavachalcone

Antibacterial; Antibiotic Microbiology/Virology
Bavachalcone 是从补骨脂中分离的化合物,广泛用于中药,具有抗生素和抗癌等活性。
T5770 Alisol B

RANKL/RANK NF-κB
Alisol B 是一种具有用于骨科疾病研究潜力的化合物,通过分化破骨细胞发挥其功能。
T3S1729 Dihydrolycorine

Others Others
Dihydrolycorine 是分离自Lycoris radiate 草药中,是一种真核细胞中蛋白质合成的抑制剂。
TN1711 Gossypetin

Antioxidant; p38 MAPK; MAPK; Antibacterial MAPK; Microbiology/Virology; oxidation-reduction
Gossypetin 是一种可从Rhodiola rosea Linn.中提取的六羟基化的类黄酮,是一种有效的 MKK3 和 MKK6 抑制剂,可强烈减弱 MKK3/6-p38 信号传导途径。Gossypetin 具有抗突变、抗动脉粥样硬化、抗氧化以及细胞保护和抗菌作用,它通过下调溶酶体酪蛋白酶 K 的活性和诱导肌动蛋白环破骨细胞中的自噬相关蛋白来抑制骨吸收。
T6316 Calcitriol

Topitriol,Rocaltrol,Calcijex,RO215535,骨化三醇,1,25-Dihydroxyvitamin D3

Endogenous Metabolite Metabolism
Calcitriol (1,25-Dihydroxyvitamin D3) 是一种维他命 D 的代谢物,一种维他命 D 受体 (VDR) 的激动剂 (IC50=0.4 nM)。Calcitriol 增加肠道对钙和磷的吸收,并与甲状旁腺激素一起增加了骨吸收。
T3777 Praeruptorin A

(+)-Praeruptorin A,白花前胡甲素

CaMK; NF-κB Neuroscience; NF-κB
Praeruptorin A ((+)-Praeruptorin A) 是一种白花前胡的主要生物活性成分。它能够抑制 NF-κB 活化,发挥抗炎作用。
T3804 Neomangiferin

Mangiferin 7-glucoside,新芒果苷

Phosphatase Metabolism
Neomangiferin (Mangiferin 7-glucoside) 是一种天然的 C-glucosyl xanthone,分离自干燥的Anemarrhena asphodeloides 的根茎中。它能够减轻大鼠高脂饮食诱导的非酒精性脂肪性肝病 (NAFLD)。
T4237 Rubiadin-1-methyl ether

Rubiadin 1-methyl ether,3-羟基-1-甲氧基-2-甲基蒽醌

Anti-infection; NF-κB Microbiology/Virology; NF-κB
Rubiadin-1-methyl ether (Rubiadin 1-methyl ether) 是一种巴戟天中的蒽醌类化合物,能够抑制 NF-κB p65 的磷酸化和 IκBα 的降解以及减少 p65 的核转位,阻碍破骨细胞的骨吸收。
T3674 Hydroxysafflor yellow A

藏红花,羟基红花黄色素A,HSYA,Safflomin A

TGF-beta/Smad Stem Cells
Hydroxysafflor yellow A (Safflomin A) 是一种黄酮类天然产物,从中药红花中分离得到,具有抗癌作用。
T2698 Asperosaponin VI

Akebia saponin D,Asperosaponin Ⅵ,川续断皂苷 VI

Apoptosis; Others; Caspase Apoptosis; Others; Proteases/Proteasome
Asperosaponin VI (Akebia saponin D) 是一种来自续断壁的皂苷组分。它通过增加 Bcl-2/Bax 比值,降低活性 caspase-3 表达,以及增强 p-Akt 和 p-CREB,从而抑制缺氧诱导的心肌细胞凋亡。它通过 BMP-2/p38 和 ERK1/2 信号途径诱导成骨细胞分化。
T8194L Soy Isoflavone

Others Others
Soy Isoflavone 是从豆科植物的种子中提取的。大豆中的异黄酮是天然植物雌激素,具有很好的药用价值,可以降低女性乳腺癌的发病率,缓解更年期症状,增加骨密度。
T1257 Bestatin

Ubenimex,乌苯美司

Others; Aminopeptidase; Antibacterial; Antibiotic; LTR Immunology/Inflammation; Metabolism; Microbiology/Virology; Others
Bestatin (Ubenimex) 是 CD13 (Aminopeptidase N)/APN 和 leukotriene A4 hydrolase 抑制剂,可用于癌症研究。
T3O2749 L-Leucine

(S)-Leucine,Leu,L-亮氨酸,亮氨酸

mTOR PI3K/Akt/mTOR signaling
L-Leucine ((S)-Leucine) 是必需的支链氨基酸,能够激活 mTOR 信号通路。
T6S0139 Neobavaisoflavone

Apoptosis; DNA/RNA Synthesis Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair
Neobavaisoflavone 是一种从Psoralea corylifolia 的种子中分离出来的类黄酮。它具有抗炎,抗癌和抗氧化的作用。它在中至高浓度下可抑制 DNA 聚合酶,也可抑制血小板聚集。
T20089 ATP

Atipi,ATP disodium salt hydrate,Triphosphoric acid adenosine ester,Ara-ATP,Triphosphaden,Adenosine triphosphate;Ara-ATP,Adenosine triphosphate

Endogenous Metabolite Metabolism
ATP (Adenosine triphosphate) 可为细胞提供能量,参与整体能量平衡,维持细胞内稳态。ATP 可以通过与特异性嘌呤能受体的相互作用充当细胞外信号分子,以介导神经传递、炎症、细胞凋亡和骨重塑等多种过程。
T1549 Raloxifene hydrochloride

LY156758 hydrochloride,盐酸雷洛昔芬,Raloxifene HCl,LY139481 hydrochloride,Keoxifene hydrochloride,LY156758 (Keoxifene) HCl

Estrogen Receptor/ERR; Others; MAO; Estrogen/progestogen Receptor; Autophagy Autophagy; Endocrinology/Hormones; Metabolism; Neuroscience; Others
Raloxifene hydrochloride (LY156758 hydrochloride) 是一种选择性且可口服的雌激素受体调节剂,用于预防绝经后妇女的骨质疏松症。它对骨骼和胆固醇代谢具有雌激素激动作用,但对乳腺和子宫组织具有完全的雌激素拮抗作用。
T2818 Methyl Vanillate

Reactive Oxygen Species; Wnt/beta-catenin; Endogenous Metabolite Cytoskeletal Signaling; Immunology/Inflammation; Metabolism; NF-κB; Stem Cells
Methyl vanillate 是一种枳椇属植物中的提取物,是Wnt/β-catenin 信号通路活化剂,是一种香草酸的甲酯。它具有抗氧化作用。
T1183 Retinol

all-trans-Retinol,视黄醇,Vitamin A,Vitamin A1,Alphalin

Others Others
Retinol (Vitamin A) 属于天然维生素,具有脂溶性。Retinol 在视网膜的代谢功能、上皮组织的生长和分化、骨骼的生长、生殖和免疫反应中起重要作用。
TN1215 (2S)-2'-Methoxykurarinone

2'-甲氧基苦参黄素,2'-Methoxykurarinone,2'-O-Methylkurarinone

Akt; Antifection Cytoskeletal Signaling; Microbiology/Virology; PI3K/Akt/mTOR signaling
(2S)-2'-Methoxykurarinone 是一种分离自苦参根中的化合物,具有抗炎、解热、抗糖尿病和抗肿瘤活性。它对人髓系白血病 HL-60 细胞具有细胞毒活性。它能够下调 RANKL 信号,抑制破骨细胞形成和骨吸收。
T4S1050 Pristimerin

扁塑藤素,Celastrol methyl ester

NF-κB; Antibacterial Microbiology/Virology; NF-κB
Pristimerin (Celastrol methyl ester) 是一种可逆的单酰基甘油脂肪酶高效抑制剂,IC50值为93 nM。
------------------------ 更多 ------------------------

天然产物

Tigogenin
Cat.No: T5751
Synonym:
Target: Others
Sciadopitysin
Cat.No: T5S2129
Synonym:
Target: TNF, NF-κB
Cycloastragenol
Cat.No: T5575
Synonym: 环黄芪醇,Cyclogalegenol,Astramembrangenin
Target: Epigenetic Reader Domain, Telomerase
Cimicifugoside H-1
Cat.No: TN1494
Synonym: 黑升麻苷H-1
Target: Others
Obtusifolin
Cat.No: T4S0969
Synonym: 决明蒽醌,决明蒽醌;美决明子素
Target: Antioxidant, NF-κB
Costunolide
Cat.No: T2902
Synonym: Costus lactone,NSC 106404,Costunolid,(+)-Costunolide,木香烃内酯
Target: Apoptosis, Endogenous Metabolite, Telomerase
(-)-Epigallocatechin Gallate
Cat.No: T2988
Synonym: Epigallocatechol Gallate,(-)-表没食子儿茶素没食子酸酯,EGCG
Target: Ferroptosis, Reactive Oxygen Species, HIV Protease, Mitochondrial Metabolism, Endogenous Metabolite, Autophagy
N-(3-Methoxybenzyl)-(9Z,12Z,15Z)-octadecatrienamide
Cat.No: TN7036
Synonym: (9Z,12Z,15Z)-N-[(3-Methoxyphenyl)methyl]-9,12,15-octadecatrienamide,间-甲氧基苄基-亚麻酰胺,Macamide Impurity 14
Target: Wnt/beta-catenin
zerumbone
Cat.No: T5712
Synonym: 花薑酮,球姜酮
Target: Antioxidant, HSV
Rubone
Cat.No: T24744
Synonym:
Target: Others
(+)-Medicarpin
Cat.No: T13768
Synonym:
Target: Estrogen/progestogen Receptor
Tectorigenin
Cat.No: T3488
Synonym: 4',5,7-Trihydroxy-6-methoxyisoflavone,Tectorigenine,鸢尾黄酮,鸢尾黄素
Target: Apoptosis
Tetracycline hydrochloride
Cat.No: T0912
Synonym: NCI-c55561,盐酸四环素,Tetracycline HCl
Target: ribosome, Antibacterial, Antibiotic
Veraguensin
Cat.No: TN1117
Synonym:
Target: p38 MAPK, NF-κB, Antibiotic, Parasite, Antifection
Dalbergin
Cat.No: TJS0856
Synonym: 黄檀素,6-Hydroxy-7-Methoxy-4-Phenylcoumarin
Target: Others
Glycitin
Cat.No: T2820
Synonym: 黄豆黄苷,Glycitein-7-β-O-glucoside,Glycitein 7-O-β-glucoside
Target: Others, Influenza Virus, Antibacterial
3,7,4'-Trihydroxyflavone
Cat.No: TN2143
Synonym: Resokaempferol,5-Deoxykampferol
Target: DNA
H-HoArg-OH
Cat.No: T8103
Synonym:
Target: Endogenous Metabolite, Phosphorylase
Poncirin
Cat.No: T3S2312
Synonym: 枸橘苷,Isosakuranetin-7-neohesperidoside
Target: Apoptosis, Others
Batilol
Cat.No: T3004
Synonym: 鲨肝醇,Batilolum,Stearyl monoglyceride,Batyl alcohol,1-O-Octadecylglycerol
Target: Others, Endogenous Metabolite
3-(3-Hydroxyphenyl)propionic Acid
Cat.No: T7437
Synonym: m-Hydroxyphenylpropionic acid,3-Hydroxyhydrocinnamic acid,3-(3-羟基苯基)丙酸
Target: Others, Endogenous Metabolite
Imperatorin
Cat.No: T2845
Synonym: Ammidin,8-Isoamylenoxypsoralen,欧前胡素,8-Isopentenyloxypsoralene,Marmelosin,Pentosalen
Target: TRP/TRPV Channel, AChR, AChE, NOD
Icariside I
Cat.No: T3808
Synonym: 淫羊藿次苷I,Lcariside I,Icariin I,Icarisid I
Target: Others
3′,4′,7-Trihydroxyflavone 
Cat.No: TN3209
Synonym:
Target: ATPase, Others, p38 MAPK, NF-κB
Gelsemine
Cat.No: T5S0662
Synonym: 钩吻碱,Gelsemin
Target: Antioxidant
Chondroitin sulfate
Cat.No: T2980
Synonym: Chonsurid,Chondroitin polysulfate,硫酸软骨素
Target: MMP, Others, Endogenous Metabolite, NO Synthase
Paeonolide
Cat.No: T6S1657
Synonym:
Target: Others
Curculigoside
Cat.No: T6S1966
Synonym: Curculigoside A,仙茅苷
Target: Antioxidant, NF-κB, JAK, STAT
Eleutheroside E
Cat.No: T3662
Synonym:
Target: NF-κB
Astragaloside II
Cat.No: T3924
Synonym: 黄芪皂苷 II,Astrasieversianin VIII
Target: TGF-beta/Smad
Bavachalcone
Cat.No: T3S0137
Synonym:
Target: Antibacterial, Antibiotic
Alisol B
Cat.No: T5770
Synonym:
Target: RANKL/RANK
Dihydrolycorine
Cat.No: T3S1729
Synonym:
Target: Others
Gossypetin
Cat.No: TN1711
Synonym:
Target: Antioxidant, p38 MAPK, MAPK, Antibacterial
Calcitriol
Cat.No: T6316
Synonym: Topitriol,Rocaltrol,Calcijex,RO215535,骨化三醇,1,25-Dihydroxyvitamin D3
Target: Endogenous Metabolite
Praeruptorin A
Cat.No: T3777
Synonym: (+)-Praeruptorin A,白花前胡甲素
Target: CaMK, NF-κB
Neomangiferin
Cat.No: T3804
Synonym: Mangiferin 7-glucoside,新芒果苷
Target: Phosphatase
Rubiadin-1-methyl ether
Cat.No: T4237
Synonym: Rubiadin 1-methyl ether,3-羟基-1-甲氧基-2-甲基蒽醌
Target: Anti-infection, NF-κB
Hydroxysafflor yellow A
Cat.No: T3674
Synonym: 藏红花,羟基红花黄色素A,HSYA,Safflomin A
Target: TGF-beta/Smad
Asperosaponin VI
Cat.No: T2698
Synonym: Akebia saponin D,Asperosaponin Ⅵ,川续断皂苷 VI
Target: Apoptosis, Others, Caspase
Soy Isoflavone
Cat.No: T8194L
Synonym:
Target: Others
Bestatin
Cat.No: T1257
Synonym: Ubenimex,乌苯美司
Target: Others, Aminopeptidase, Antibacterial, Antibiotic, LTR
L-Leucine
Cat.No: T3O2749
Synonym: (S)-Leucine,Leu,L-亮氨酸,亮氨酸
Target: mTOR
Neobavaisoflavone
Cat.No: T6S0139
Synonym:
Target: Apoptosis, DNA/RNA Synthesis
ATP
Cat.No: T20089
Synonym: Atipi,ATP disodium salt hydrate,Triphosphoric acid adenosine ester,Ara-ATP,Triphosphaden,Adenosine triphosphate;Ara-ATP,Adenosine triphosphate
Target: Endogenous Metabolite
Raloxifene hydrochloride
Cat.No: T1549
Synonym: LY156758 hydrochloride,盐酸雷洛昔芬,Raloxifene HCl,LY139481 hydrochloride,Keoxifene hydrochloride,LY156758 (Keoxifene) HCl
Target: Estrogen Receptor/ERR, Others, MAO, Estrogen/progestogen Receptor, Autophagy
Methyl Vanillate
Cat.No: T2818
Synonym:
Target: Reactive Oxygen Species, Wnt/beta-catenin, Endogenous Metabolite
Retinol
Cat.No: T1183
Synonym: all-trans-Retinol,视黄醇,Vitamin A,Vitamin A1,Alphalin
Target: Others
(2S)-2'-Methoxykurarinone
Cat.No: TN1215
Synonym: 2'-甲氧基苦参黄素,2'-Methoxykurarinone,2'-O-Methylkurarinone
Target: Akt, Antifection
Pristimerin
Cat.No: T4S1050
Synonym: 扁塑藤素,Celastrol methyl ester
Target: NF-κB, Antibacterial
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Cat. No. Product Name Species Expression System
TMPY-00680 BMP-2 Protein, Human, Mouse, Rat, Rhesus, Canine, Recombinant (hFc)

bone morphogenetic protein 2

Human,Mouse,Rat,Rhesus,Canine HEK293 Cells
BMP-2 Protein, Human, Mouse, Rat, Rhesus, Canine, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 39.5 kDa and the accession number is C8C060.
TMPY-03235 BST2 Protein, Human, Recombinant (His)

bone marrow stromal cell antigen 2,CD317,TETHERIN

Human HEK293 Cells
BST2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.9 kDa and the accession number is Q10589.
TMPY-00663 Alkaline Phosphatase/ALPL Protein, Human, Recombinant (His)

alkaline phosphatase, liver/bone/kidney,TNSALP,AP-T...

Human HEK293 Cells
Alkaline Phosphatase/ALPL Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 55 kDa and the accession number is A0A024RAB4.
TMPY-06842 BMP-4 Protein, Human, Recombinant (E399D)

OFC11,BMP2B,bone morphogenetic protein 4,BMP2B1,ZYM...

Human E. coli
BMP-4 Protein, Human, Recombinant (E399D) is expressed in E. coli expression system. The predicted molecular weight is 13.25 kDa and the accession number is P12644.
TMPK-00807 Osteopontin Protein, Mouse, Recombinant (His)

ETA-1,SPP1,OPN,Bone sialoprotein 1,BNSP,SPP-1,Osteo...

Mouse HEK293 Cells
Secreted phosphoprotein 1 (SPP1) expression in TAMs isolated from lung adenocarcinoma tissues and PMA-treated THP-1 cells were measured. Macrophage polarization was identified by flow cytometric analysis. Cell migration and apoptosis were assessed by Transwell migration assays and flow cytometric analysis, respectively. SPP1 is highly expressed in tumor tissues and TAMs isolated from patients with an advanced TNM stage, and also in PMA-treated THP-1 cells.
TMPY-01059 BMPR2 Protein, Human, Recombinant (His)

POVD1,PPH1,BMPR3,BRK-3,BMPR-II,bone morphogenetic p...

Human HEK293 Cells
BMPR2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.6 kDa and the accession number is Q13873.
TMPY-00681 BMP-5 Protein, Human, Recombinant (hFc)

bone morphogenetic protein 5

Human HEK293 Cells
Bone Morphogenetic Protein 5 (BMP-5) is a member of the structurally and functionally related bone morphogenetic proteins (BMPs) which constitute a novel subfamily of the transforming growth factor β (TGF-β) superfamily. In agreement with a possible role in the control of cell death, BMP-5 exhibited a regulated pattern of expression in the interdigital tissue. Transcripts of BMP-5 and BMP-5 protein were abundant within the cytoplasm of the fragmenting apoptotic interdigital cells in a way sugges...
TMPY-01136 BMP-2 Protein, Human, Mouse, Rat, Rhesus, Canine, Recombinant

bone morphogenetic protein 2

Human,Mouse,Rat,Rhesus,Canine E. coli
BMP-2 Protein, Human, Mouse, Rat, Rhesus, Canine, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 13 kDa and the accession number is C8C060.
TMPY-03297 BMP-2 Protein, Danio rerio (zebrafish), Recombinant

bone morphogenetic protein 2

Danio rerio (zebrafish) E. coli
BMP-2 Protein, Danio rerio (zebrafish), Recombinant is expressed in E. coli expression system. The predicted molecular weight is 13.2 kDa and the accession number is B3DI86.
TMPY-03038 CD157 Protein, Rat, Recombinant (His)

bone marrow stromal cell antigen 1

Rat HEK293 Cells
CD157 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31.2 kDa and the accession number is Q63072.
TMPH-01016 GDF10 Protein, Human, Recombinant (His)

Bone-inducing protein,Bone morphogenetic p...

Human E. coli
Growth factor involved in osteogenesis and adipogenesis. Plays an inhibitory role in the process of osteoblast differentiation via SMAD2/3 pathway. Plays an inhibitory role in the process of adipogenesis. GDF-10 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 16.1 kDa and the accession number is P55107.
TMPY-00614 BMPR1A/ALK-3 Protein, Canine, Recombinant (hFc)

bone morphogenetic protein receptor, type IA

Canine HEK293 Cells
BMPR1A/ALK-3 Protein, Canine, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 41.2 kDa and the accession number is A0A8C0S7K5.
TMPH-01015 BMP-3 Protein, Human, Recombinant (His)

BMP3A,Bone morphogenetic protein 3A,BMP3,Osteogenin...

Human E. coli
Growth factor of the TGF-beta superfamily that plays an essential role in developmental process by inducing and patterning early skeletal formation and by negatively regulating bone density. Antagonizes the ability of certain osteogenic BMPs to induce osteoprogenitor differentitation and ossification. Initiates signaling cascades by associating with type II receptor ACVR2B to activate SMAD2-dependent and SMAD-independent signaling cascades including TAK1 and JNK pathways. BMP-3 Protein, Human, R...
TMPY-03037 CD157 Protein, Rat, Recombinant (hFc)

bone marrow stromal cell antigen 1

Rat HEK293 Cells
CD157 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 56.8 kDa and the accession number is Q63072.
TMPY-00968 CD157 Protein, Human, Recombinant (His)

bone marrow stromal cell antigen 1,CD157

Human HEK293 Cells
CD157 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31.4 kDa and the accession number is Q10588-1.
TMPH-01014 BMP-2 Protein, Human, Recombinant (His)

BMP-2,Bone morphogenetic protein 2A,BMP2,BMP2A,...

Human E. coli
BMP-2 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 16.9 kDa and the accession number is P12643.
TMPH-01017 BMP-4 Protein, Human, Recombinant (His)

BMP4,Bone morphogenetic protein 4,BMP-4

Human E. coli
BMP-4 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 15.4 kDa and the accession number is P12644.
TMPY-03193 BST2 Protein, Human, Recombinant (hFc)

CD317,TETHERIN,bone marrow stromal cell antigen 2

Human HEK293 Cells
BST2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 41 kDa and the accession number is Q10589.
TMPH-01011 PRG2 Protein, Human, Recombinant (GST & His)

Bone marrow proteoglycan,PRG2,Proteoglycan 2

Human E. coli
Cytotoxin and helminthotoxin. Also induces non-cytolytic histamine release from human basophils. Involved in antiparasitic defense mechanisms and immune hypersensitivity reactions. The proform acts as a proteinase inhibitor, reducing the activity of PAPPA. PRG2 Protein, Human, Recombinant (GST & His) is expressed in E. coli expression system with N-6xHis-GST tag. The predicted molecular weight is 41.2 kDa and the accession number is P13727.
TMPH-02552 BMP3 Protein, Mouse, Recombinant (Myc)

Bone morphogenetic protein 3,Bmp3,BMP-3

Mouse E. coli
Negatively regulates bone density. Antagonizes the ability of certain osteogenic BMPs to induce osteoprogenitor differentitation and ossification.
TMPH-00228 BMP-4 Protein, Bovine, Recombinant (GST)

Bone morphogenetic protein 4,BMP4,BMP-4

Bovine E. coli
BMP-4 Protein, Bovine, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 40.6 kDa and the accession number is Q2KJH1.
TMPJ-00445 IBSP Protein, Mouse, Recombinant (His)

BNSP,IBSP,Integrin binding sialoprotein,Cell binding sialopr...

Mouse HEK293 Cells
Bone sialoprotein 2(IBSP) is a monomeric non‑collagenous member of the SIBLING family of extracellular matrix proteins. It is principally associated with the early stages of bone mineralization. Mouse IBSP is synthesized as a 324 amino acid (aa) precursor that contains a 16 aa signal sequence and a 308 aa mature region. The mature segment is divided into a basic N‑terminus (aa 17 ‑ 62), a central region (aa 63 ‑ 233), and an acidic C‑terminus (aa 234 ‑ 317). IBSP is highly glycosylated, sulfate...
TMPJ-00924 Decorin Protein, Mouse, Recombinant (His)

PG40,Bone proteoglycan II,Decorin,Dcn,PG-S2

Mouse HEK293 Cells
Decorin, also known as PG40 and DCN, is a member of the class I family of small leucine-rich proteoglycans (SLRPs) that is expressed in the stroma of various forms of cancer and has been recently proposed to act as a guardian from the matrix. Mature human Decorin contains 12 tandem LRR and shares 80% and 78% aa sequence identity with mouse and rat Decorin, respectively. Decorin embraces numerous functions including: regulation of collagen fibrillogenesis, hepatic carcinogenesis, fetal membrane a...
TMPH-01414 GDF2 Protein, Human, Recombinant (His)

Growth/differentiation factor 2,Bone morphogenetic ...

Human P. pastoris (Yeast)
Potent circulating inhibitor of angiogenesis. Signals through the type I activin receptor ACVRL1 but not other Alks. Signaling through SMAD1 in endothelial cells requires TGF-beta coreceptor endoglin/ENG. GDF2 Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 16.3 kDa and the accession number is Q9UK05.
TMPY-00431 BMP-4 Protein, Mouse, Recombinant (rFc)

bone morphogenetic protein 4,Bmp-4,Bmp2b-1,Bmp2b,Bm...

Mouse HEK293 Cells
BMP-4 Protein, Mouse, Recombinant (rFc) is expressed in HEK293 mammalian cells with rFc tag. The predicted molecular weight is 40.6 kDa and the accession number is P21275.
TMPH-00264 Decorin Protein, Bovine, Recombinant (His)

Decorin,Bone proteoglycan II,DCN,PG-S2

Bovine E. coli
May affect the rate of fibrils formation. Decorin Protein, Bovine, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 40.5 kDa and the accession number is P21793.
TMPY-03362 BMPRIB Protein, Human, Recombinant (hFc)

ALK6,bone morphogenetic protein receptor, type IB,C...

Human HEK293 Cells
BMPRIB Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 39.7 kDa and the accession number is O00238-1.
TMPY-04367 BMPRIB Protein, Human, Recombinant (aa 149-502, His & GST)

bone morphogenetic protein receptor, type IB,CDw293...

Human Baculovirus Insect Cells
BMPRIB Protein, Human, Recombinant (aa 149-502, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 68.3 kDa and the accession number is O00238-1.
TMPH-00496 Osteocalcin Protein, Canine, Recombinant (His & KSI)

BGLAP,Gamma-carboxyglutamic acid-containing protein,Osteocal...

Canine E. coli
Osteocalcin Protein, Canine, Recombinant (His & KSI) is expressed in E. coli.
TMPH-01413 GDF11 Protein, Human, Recombinant (His & SUMO)

Bone morphogenetic protein 11,GDF11,Growth/differen...

Human E. coli
Secreted signal that acts globally to regulate anterior/posterior axial patterning during development. May play critical roles in patterning both mesodermal and neural tissues. It is required for proper vertebral patterning and orofacial development. Signals through activin receptors type-2, ACVR2A and ACVR2B, and activin receptors type-1, ACVR1B, ACVR1C and TGFBR1 leading to the phosphorylation of SMAD2 and SMAD3. GDF11 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression...
TMPY-00446 Alkaline Phosphatase/ALPL Protein, Mouse, Recombinant (His)

TNSALP,Akp2,alkaline phosphatase, liver/bone/kidney...

Mouse HEK293 Cells
Alkaline Phosphatase/ALPL Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 55 kDa and the accession number is B7XGA6.
TMPH-02548 Biglycan Protein, Mouse, Recombinant (His)

PG-S1,Bone/cartilage proteoglycan I,Bgn,Biglycan

Mouse E. coli
May be involved in collagen fiber assembly. Biglycan Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 43.4 kDa and the accession number is P28653.
TMPH-02818 Osteocalcin Protein, Mouse, Recombinant (His & SUMO)

Bone Gla protein,Gamma-carboxyglutamic acid-contain...

Mouse E. coli
Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium.
TMPY-00594 Alkaline Phosphatase/ALPL Protein, Mouse, Recombinant (hFc)

Akp-2,TNSALP,TNAP,alkaline phosphatase, liver/bone/...

Mouse HEK293 Cells
Alkaline Phosphatase/ALPL Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 80.3 kDa and the accession number is B7XGA6.
TMPY-01764 BMPR1A/ALK-3 Protein, Human, Recombinant (His)

bone morphogenetic protein receptor, type IA,ALK3,A...

Human HEK293 Cells
BMPR1A/ALK-3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.7 kDa and the accession number is P36894.
TMPY-00962 BMPR1A/ALK-3 Protein, Mouse, Recombinant (His & hFc)

Bmpr,bone morphogenetic protein receptor, type IA,B...

Mouse HEK293 Cells
BMPR1A/ALK-3 Protein, Mouse, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 42 kDa and the accession number is P36895.
TMPH-03346 Osteocalcin Protein, Rat, Recombinant (GST)

Bone Gla protein,Osteocalcin,Bglap,Gamma-carboxyglu...

Rat E. coli
Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium. Osteocalcin Protein, Rat, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 32.6 kDa and the accession number is P04640.
TMPH-00380 Osteocalcin Protein, Chicken, Recombinant (His & KSI)

Bone Gla protein,BGLAP,Osteocalcin,Gamma-carboxyglu...

Chicken E. coli
Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium. Osteocalcin Protein, Chicken, Recombinant (His & KSI) is expressed in E. coli expression system with N-6xHis-KSI tag. The predicted molecular weight is 20.7 kDa and the accession number is P02822.
TMPY-05485 BMPR1A/ALK-3 Protein, Human, Recombinant (hFc)

ACVRLK3,SKR5,10q23del,CD292,bone morphogenetic prot...

Human HEK293 Cells
BMPR1A/ALK-3 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 40.9 kDa and the accession number is P36894.
TMPY-01374 BMPR1A/ALK-3 Protein, Mouse, Recombinant (His)

ALK3,BMPR-IA,bone morphogenetic protein receptor, t...

Mouse HEK293 Cells
BMPR1A/ALK-3 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.8 kDa and the accession number is P36895.
TMPJ-00713 GDF-11 Protein, Human, Recombinant

Growth/differentiation factor 11,Bone morphogenetic...

Human HEK293 Cells
Growth/differentiation factor 11(GDF-11) is a secreted protein, which belongs to the transforming growth factor beta superfamily. GDF-11 controls anterior-posterior patterning by regulating the expression of Hox genes. The secreted signal acts globally to specify positional identity along the anterior/posterior axis during development. GDF11 has been shown to suppress neurogenesis through a pathway similar to that of myostatin, including stopping the progenitor cell-cycle during G-phase. The si...
TMPY-01178 CD157 Protein, Mouse, Recombinant (His)

CD157,bone marrow stromal cell antigen 1,BP-3,Bsta1...

Mouse HEK293 Cells
CD157 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 30.9 kDa and the accession number is A0A0R4J190.
TMPY-02674 BST2 Protein, Mouse, Recombinant (hFc)

2310015I10Rik,bone marrow stromal cell antigen 2,C8...

Mouse HEK293 Cells
BST2 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 40 kDa and the accession number is Q8R2Q8.
TMPY-04742 BST2 Protein, Mouse, Recombinant (His)

Bst-2,GREG,bone marrow stromal cell antigen 2,C8704...

Mouse HEK293 Cells
BST2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 13.6 kDa and the accession number is Q8R2Q8.
TMPH-01019 BMP-7 Protein, Human, Recombinant (GST)

BMP-7,OP1,BMP7,OP-1,Bone morphogenetic protein 7,Os...

Human E. coli
BMP-7 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 42.7 kDa and the accession number is P18075.
TMPJ-01473 BMP-7 Protein, Human, Recombinant

Eptotermin alfa,OP-1,OP1,Osteogenic protein 1,Bone ...

Human HEK293 Cells
Bone morphogenetic protein 7 (BMP7), also known as osteogenic protein-1 (OP-1) is a member of Transforming growth factor-β (TGF-β) family of proteins. Bone morphogenetic proteins were discovered in 1965 by Marshal Urist, of which BMP7 is of particular interest in this review being a leptin-independent anorexinogen and having role in energy expenditure in the brown adipose tissue, which makes it a potential target for preventing/treating obesity. As it has been established that Obesity displays a...
TMPH-01013 BMP-15 Protein, Human, Recombinant (His & Myc)

BMP15,GDF-9B,BMP-15,Bone morphogenetic protein 15,G...

Human E. coli
May be involved in follicular development. Oocyte-specific growth/differentiation factor that stimulates folliculogenesis and granulosa cell (GC) growth. BMP-15 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 21.4 kDa and the accession number is O95972.
TMPH-01012 BMP-1 Protein, Human, Recombinant (His)

PCOLC,mTld,Procollagen C-proteinase,Mammalian tolloid protei...

Human E. coli
BMP-1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 102.0 kDa and the accession number is P13497.
TMPK-00676 Osteopontin Protein, Human, Recombinant (aa 17-300, His)

BSP-1,Nephropontin,BNSP,ETA-1,OPN,Bone sialoprotein...

Human HEK293 Cells
Osteopontin Protein, Human, Recombinant (aa 17-300, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 34.8 kDa and the accession number is A0A024RDE6.
TMPK-00538 Osteopontin Protein, Cynomolgus, Recombinant (His)

BSP-1,BNSP,SPP1,Nephropontin,OPN,Bone sialoprotein ...

Cynomolgus HEK293 Cells
Osteopontin Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 33.16 kDa and the accession number is A0A2K5WL90.
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重组蛋白

BMP-2 Protein, Human, Mouse, Rat, Rhesus, Canine, Recombinant (hFc)
Cat.No: TMPY-00680
Species: Human,Mouse,Rat,Rhesus,Canine
Expression System: HEK293 Cells
BST2 Protein, Human, Recombinant (His)
Cat.No: TMPY-03235
Species: Human
Expression System: HEK293 Cells
Alkaline Phosphatase/ALPL Protein, Human, Recombinant (His)
Cat.No: TMPY-00663
Species: Human
Expression System: HEK293 Cells
BMP-4 Protein, Human, Recombinant (E399D)
Cat.No: TMPY-06842
Species: Human
Expression System: E. coli
Osteopontin Protein, Mouse, Recombinant (His)
Cat.No: TMPK-00807
Species: Mouse
Expression System: HEK293 Cells
BMPR2 Protein, Human, Recombinant (His)
Cat.No: TMPY-01059
Species: Human
Expression System: HEK293 Cells
BMP-5 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-00681
Species: Human
Expression System: HEK293 Cells
BMP-2 Protein, Human, Mouse, Rat, Rhesus, Canine, Recombinant
Cat.No: TMPY-01136
Species: Human,Mouse,Rat,Rhesus,Canine
Expression System: E. coli
BMP-2 Protein, Danio rerio (zebrafish), Recombinant
Cat.No: TMPY-03297
Species: Danio rerio (zebrafish)
Expression System: E. coli
CD157 Protein, Rat, Recombinant (His)
Cat.No: TMPY-03038
Species: Rat
Expression System: HEK293 Cells
GDF10 Protein, Human, Recombinant (His)
Cat.No: TMPH-01016
Species: Human
Expression System: E. coli
BMPR1A/ALK-3 Protein, Canine, Recombinant (hFc)
Cat.No: TMPY-00614
Species: Canine
Expression System: HEK293 Cells
BMP-3 Protein, Human, Recombinant (His)
Cat.No: TMPH-01015
Species: Human
Expression System: E. coli
CD157 Protein, Rat, Recombinant (hFc)
Cat.No: TMPY-03037
Species: Rat
Expression System: HEK293 Cells
CD157 Protein, Human, Recombinant (His)
Cat.No: TMPY-00968
Species: Human
Expression System: HEK293 Cells
BMP-2 Protein, Human, Recombinant (His)
Cat.No: TMPH-01014
Species: Human
Expression System: E. coli
BMP-4 Protein, Human, Recombinant (His)
Cat.No: TMPH-01017
Species: Human
Expression System: E. coli
BST2 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-03193
Species: Human
Expression System: HEK293 Cells
PRG2 Protein, Human, Recombinant (GST & His)
Cat.No: TMPH-01011
Species: Human
Expression System: E. coli
BMP3 Protein, Mouse, Recombinant (Myc)
Cat.No: TMPH-02552
Species: Mouse
Expression System: E. coli
BMP-4 Protein, Bovine, Recombinant (GST)
Cat.No: TMPH-00228
Species: Bovine
Expression System: E. coli
IBSP Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-00445
Species: Mouse
Expression System: HEK293 Cells
Decorin Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-00924
Species: Mouse
Expression System: HEK293 Cells
GDF2 Protein, Human, Recombinant (His)
Cat.No: TMPH-01414
Species: Human
Expression System: P. pastoris (Yeast)
BMP-4 Protein, Mouse, Recombinant (rFc)
Cat.No: TMPY-00431
Species: Mouse
Expression System: HEK293 Cells
Decorin Protein, Bovine, Recombinant (His)
Cat.No: TMPH-00264
Species: Bovine
Expression System: E. coli
BMPRIB Protein, Human, Recombinant (hFc)
Cat.No: TMPY-03362
Species: Human
Expression System: HEK293 Cells
BMPRIB Protein, Human, Recombinant (aa 149-502, His & GST)
Cat.No: TMPY-04367
Species: Human
Expression System: Baculovirus Insect Cells
Osteocalcin Protein, Canine, Recombinant (His & KSI)
Cat.No: TMPH-00496
Species: Canine
Expression System: E. coli
GDF11 Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-01413
Species: Human
Expression System: E. coli
Alkaline Phosphatase/ALPL Protein, Mouse, Recombinant (His)
Cat.No: TMPY-00446
Species: Mouse
Expression System: HEK293 Cells
Biglycan Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02548
Species: Mouse
Expression System: E. coli
Osteocalcin Protein, Mouse, Recombinant (His & SUMO)
Cat.No: TMPH-02818
Species: Mouse
Expression System: E. coli
Alkaline Phosphatase/ALPL Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-00594
Species: Mouse
Expression System: HEK293 Cells
BMPR1A/ALK-3 Protein, Human, Recombinant (His)
Cat.No: TMPY-01764
Species: Human
Expression System: HEK293 Cells
BMPR1A/ALK-3 Protein, Mouse, Recombinant (His & hFc)
Cat.No: TMPY-00962
Species: Mouse
Expression System: HEK293 Cells
Osteocalcin Protein, Rat, Recombinant (GST)
Cat.No: TMPH-03346
Species: Rat
Expression System: E. coli
Osteocalcin Protein, Chicken, Recombinant (His & KSI)
Cat.No: TMPH-00380
Species: Chicken
Expression System: E. coli
BMPR1A/ALK-3 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-05485
Species: Human
Expression System: HEK293 Cells
BMPR1A/ALK-3 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01374
Species: Mouse
Expression System: HEK293 Cells
GDF-11 Protein, Human, Recombinant
Cat.No: TMPJ-00713
Species: Human
Expression System: HEK293 Cells
CD157 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01178
Species: Mouse
Expression System: HEK293 Cells
BST2 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-02674
Species: Mouse
Expression System: HEK293 Cells
BST2 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-04742
Species: Mouse
Expression System: HEK293 Cells
BMP-7 Protein, Human, Recombinant (GST)
Cat.No: TMPH-01019
Species: Human
Expression System: E. coli
BMP-7 Protein, Human, Recombinant
Cat.No: TMPJ-01473
Species: Human
Expression System: HEK293 Cells
BMP-15 Protein, Human, Recombinant (His & Myc)
Cat.No: TMPH-01013
Species: Human
Expression System: E. coli
BMP-1 Protein, Human, Recombinant (His)
Cat.No: TMPH-01012
Species: Human
Expression System: E. coli
Osteopontin Protein, Human, Recombinant (aa 17-300, His)
Cat.No: TMPK-00676
Species: Human
Expression System: HEK293 Cells
Osteopontin Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPK-00538
Species: Cynomolgus
Expression System: HEK293 Cells
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Cat. No. Product Name Target Signaling Pathways
TMID-0001 Vitamin K1-d4

Vitamin K1-d4 是 Vitamin K1 的氘代化合物。Vitamin K1 的 CAS 号为 84-80-0。Vitamin K1 (Phylloquinone) 是天然存在的维生素。Vitamin K1是血液凝固,骨和血管代谢所必须的。
TMIJ-0081 L-Leucine-d10

L-Leucine-d10 是 L-Leucine 的氘代化合物。L-Leucine 的 CAS 号为 61-90-5。L-Leucine 是必需的支链氨基酸,能够激活mTOR信号通路。
TMIJ-0374 L-Leucine-d3

L-Leucine-d3 是 L-Leucine 的氘代化合物。L-Leucine 的 CAS 号为 61-90-5。L-Leucine 是必需的支链氨基酸,能够激活mTOR信号通路。
TMID-0303 Vitamin A-d4

Retinol-d4

Vitamin A-d4 是 Vitamin A 的氘代化合物。Vitamin A 的 CAS 号为 68-26-8。Retinol 及其衍生物,在视网膜的代谢功能、上皮组织的生长和分化、骨骼的生长、生殖和免疫反应中起重要作用。膳食维生素 A 来源于植物中发现的多种类胡萝卜素。它富含肝脏、蛋黄和乳制品的脂肪成分。

同位素标记化合物

Vitamin K1-d4
Cat.No: TMID-0001
Synonym:
Target:
L-Leucine-d10
Cat.No: TMIJ-0081
Synonym:
Target:
L-Leucine-d3
Cat.No: TMIJ-0374
Synonym:
Target:
Vitamin A-d4
Cat.No: TMID-0303
Synonym: Retinol-d4
Target:
TargetMol Loading
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